Applied For Interferential Effect In Body Patents (Class 607/67)
  • Patent number: 10485977
    Abstract: An interferential current system for cardiac treatment of a patient, includes a controller, a stimulation power supply and a plurality of electrodes. The electrodes supply transcutaneous electrical impulses when supplied power by the stimulation power supply, the plurality of electrodes including at least two electrodes supplying transcutaneous electrical impulses at two different frequencies, the transcutaneous electrical impulses provided at two different frequencies giving rise to at least one beat impulse having an interference frequency. At least one sensor in communication with the controller provides data to the controller indicative of various cardiac pathologic conditions, including but not limited to, rhythm abnormalities, muscle wall contraction abnormalities, and ischemic heart disease abnormalities of the patient.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: November 26, 2019
    Assignee: Feinstein Patents, LLC
    Inventor: Peter A. Feinstein
  • Patent number: 10173065
    Abstract: Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions are disclosed. A method in accordance with a particular embodiment includes selecting a target stimulation frequency that is above a threshold frequency, with the threshold frequency corresponding to a refractory period for neurons of a target sensory neural population. The method can further include producing a patient sensation of paresthesia by directing an electrical signal to multiple sensory neurons of the target sensory neural population at the stimulation frequency, with individual neurons of the sensory neural population completing corresponding individual refractory periods at different times, resulting in an asynchronous sensory neuron response to the electrical signal.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: January 8, 2019
    Assignee: Nevro Corp.
    Inventors: Andre B. Walker, Zi-Ping Fang, Anthony V. Caparso
  • Patent number: 9039674
    Abstract: Cells that are in the process division are vulnerable to damage by AC electric fields that have specific frequency and field strength characteristics. The selective destruction of rapidly dividing cells can therefore be accomplished by imposing an AC electric field in a target region for extended periods of time at particular frequencies with particular filed strengths. Some of the cells that divide while the field is applied will be damaged, but the cells that do not divide will not be harmed. This selectively damages rapidly dividing cells like bacteria, but does not harm normal cells that are not dividing. Since the vulnerability of the dividing cells is strongly related to the alignment between the long axis of the dividing cells and the lines of force of the electric field, improved results can be obtained when the field is sequentially imposed in different directions.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: May 26, 2015
    Assignee: Novocure Limited
    Inventors: Yoram Palti, Moshe Giladi
  • Publication number: 20150127070
    Abstract: Embodiments of dermalogical cell treatment are described generally herein. Other embodiments may be described and claimed.
    Type: Application
    Filed: January 15, 2015
    Publication date: May 7, 2015
    Inventor: Jongu Na
  • Patent number: 8934983
    Abstract: The present invention is a system for mapping a high resolution image to a lower resolution electrode array and, by applying varying stimulus to neighboring electrodes, creating a perceived image greater in resolution than the electrode array. The invention is applicable to a wide range of neural stimulation devices including artificial vision and artificial hearing. By applying a sub-threshold stimulus to two neighboring electrodes where the sum of the stimuli is above the threshold of perception, a perception is created in neural tissue between the two electrodes. By adjusting the stimulus on neighboring electrodes, the location of stimulation can be altered. Further, noise can be applied to the stimulating electrode or its neighboring electrodes to reduce the threshold of stimulation.
    Type: Grant
    Filed: October 10, 2012
    Date of Patent: January 13, 2015
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Robert J Greenberg, Richard Williamson
  • Publication number: 20140330345
    Abstract: Stimulation treatments for various medical disorders, such as neurological disorders, comprise novel systems, strategies, and methods for providing TMS, electrical, magnetic, optical and other stimulation. Some stimulation methods comprise varying the stimulation parameters to improve the therapeutic efficacy of stimulation, and decrease risk of habituation and side-effects such as interference with normal brain, sensory, motor, and cognitive processes. The creation, and subsequent variation, of stimulation parameters can use sensed data in order to match, adjust, or avoid matching characteristics of the stimulation therapy relative to certain endogenous brain activities. Novel methods are described for choosing, creating and subsequently stimulating with partial signals which summate to produce therapeutic vector fields having unique temporal patterns and low- or high-frequency spectral content.
    Type: Application
    Filed: July 17, 2014
    Publication date: November 6, 2014
    Inventor: Michael Sasha John
  • Patent number: 8880178
    Abstract: Disclosed herein is a functional electrical stimulation (FES) device and system. In one embodiment, sequential bipolar pulse stimulation may be provided to an area of a living body via one or more electrode leads applied to the area via a FES device comprising a current pulse generating circuit comprising output nodes for operative coupling to the one or more electrode leads, and configured for operative coupling to a voltage supply. The current pulse generating circuit generally comprises positive and negative stimulation paths drawing from the voltage supply to respectively apply positive and negative currents through the area via the one or more electrode leads. In one example, the stimulation paths comprise respective capacitive elements, a capacitance ratio of which dictating, at least in part, an amplitude ratio of the positive and negative currents, wherein periodic alternative activation of the stimulation paths provides the sequential bipolar pulse stimulation.
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: November 4, 2014
    Assignee: University Health Network
    Inventors: Milos R. Popovic, Massimo Tarulli, Aleksandar Prodic, Peter Lehn
  • Patent number: 8750984
    Abstract: A device for stimulation via electric and magnetic fields is provided. The autonomic/vegetative nervous system can be controlled by signals in the frequency ranges of 0.05 to 0.15 Hz and 0.15 to 0.30 Hz, respectively. By addition of characteristic sinusoidal oscillations between the head and a peripheral area with the corresponding low-frequency sympathetic or parasympathetic control frequency as base oscillation and with application-typical EEG frequencies and higher-frequency sinusoidal oscillations in the range of ca. 250 to 1500 Hz, characteristic stimulation programs are established. These are applied by field applicators in the upper body area and in the lower body. The associated mat applicators distribute field energy. The field applicator is equipped with a combination of a magnetic-field-generating coil arrangement and an electrode arrangement generating the electric field. The electrode generating the electric field can at the same time be designed as a magnetic-field-generating coil.
    Type: Grant
    Filed: August 31, 2006
    Date of Patent: June 10, 2014
    Assignee: Actegy Ltd.
    Inventors: Stewart Penny, Manfred Krauss, Roland Fischer, Werner Schmidt, Mario Mobius
  • Publication number: 20130296975
    Abstract: A method and neurostimulator for providing therapy to a patient is provided. In one technique, an electrical pulsed waveform is conveyed between a caudal electrode and spinal cord tissue, thereby evoking action potentials that are orthodromically propagated along dorsal column fibers and evoking action potentials that are antidromically propagated along the DC fibers. Electrical energy is conveyed between a rostral electrode and the spinal cord tissue, thereby modulating times that the action potentials orthodromically propagated along the DC fibers arrive at the brain. In another technique, an electrical pulsed waveform is conveyed through a first electrode, thereby evoking action potentials that are propagated along a neural axon, and electrical energy is conveyed through the second electrode. The electrical energy has a frequency that is greater than a pulse rate of the electrical pulsed waveform, such that the action potentials propagated along the neural axon are blocked by the electrical energy.
    Type: Application
    Filed: July 8, 2013
    Publication date: November 7, 2013
    Inventors: Dongchul Lee, Kerry Bradley
  • Patent number: 8560082
    Abstract: Methods and devices for providing computerized adjustment to therapy parameters using real time and retrospective data processing is provided. Embodiments include receiving a respective data set from an infusion device and an analyte monitoring device for a predetermined time duration, user notification and reminder of the predetermined time duration, time synchronizing the received respective data set, detecting one or more marked data from the one or more respective data set received, establishing one or more filtering criteria to filter of retrospective or historical data based on certain condition, performing automated data analysis based on the detected one or more marked data or the data achieving certain predetermined condition to generate a modification to a therapy profile, generating and modifying rules for profile modification, and providing the generated modification to the therapy profile for reporting and transmission.
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: October 15, 2013
    Assignee: Abbott Diabetes Care Inc.
    Inventor: Charles Wei
  • Patent number: 8515551
    Abstract: An electrical interferential device comprises a circuit for delivering electrical interferential energy into the body of a patient. A sensor detects a function of the autonomic nervous system of the patient and provides an output indicative of the response of the autonomic nervous system to the electrical interferential energy. A treatment regimen is selected which uses a combination of carrier and beat frequencies and electrode placement pattern that produce a desired response in the autonomic nervous system of the patient. In one embodiment of the invention, a diagnostic tool is used to determine which combination of carrier and beat frequencies are desirable and treatment is provided by a second electrical interferential device. In another embodiment of the invention, the same diagnostic tool or a portion of the same diagnostic tool may be used to treat the patient.
    Type: Grant
    Filed: November 10, 2010
    Date of Patent: August 20, 2013
    Inventor: Donald A. Rhodes
  • Patent number: 8412345
    Abstract: A method and system for stimulating tissue using a plurality of electrodes is provided. Desired electrical parameter (e.g., field potential) values are determined at a plurality of spatial points. A plurality of constituent current sources is selected at the locations of the electrodes. The relative strengths of the constituent current sources that, when combined, result in estimated electrical parameter (e.g., field potential)|values at the spatial points that best matches the desired electrical parameter values at the spatial points are determined. The polarity and percentage of electrical current to be associated with each of the electrodes is selected based on the determined strengths of the constituent current sources. Electrical current is conveyed through the plurality of electrodes in accordance with the selected electrical current magnitudes to stimulate the tissue.
    Type: Grant
    Filed: November 2, 2010
    Date of Patent: April 2, 2013
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: Michael A. Moffitt
  • Publication number: 20130035659
    Abstract: An infusion pump, including: a specially programmed microprocessor; a drip chamber for connection to a source of fluid and to an output tubing; a pumping section including a plurality of fingers and a first actuator, controllable using the microprocessor, for sequentially displacing the plurality of finger to compress a first portion of the output tubing to displace fluid from the drip chamber through the output tubing; an inlet valve disposed between the drip chamber and the pumping section and arranged to compress the output tubing to restrict or block flow through the output tubing; and a second actuator, controllable using the microprocessor, for opening or closing the inlet valve independent of the displacement of the plurality of fingers; or for operating the inlet valve to control a rate of flow of fluid from the drip chamber to the portion of the output tubing.
    Type: Application
    Filed: August 2, 2011
    Publication date: February 7, 2013
    Applicant: SIGMA INTERNATIONAL GENERAL MEDICAL APPARATUS, LLC
    Inventors: Roger L. Hungerford, Tuan Bui
  • Patent number: 8311635
    Abstract: The present invention is a system for mapping a high resolution image to a lower resolution electrode array and, by applying varying stimulus to neighboring electrodes, creating a perceived image greater in resolution than the electrode array. The invention is applicable to a wide range of neural stimulation devices including artificial vision and artificial hearing. By applying a sub-threshold stimulus to two neighboring electrodes where the sum of the stimuli is above the threshold of perception, a perception is created in neural tissue between the two electrodes. By adjusting the stimulus on neighboring electrodes, the location of stimulation can be altered. Further, noise can be applied to the stimulating electrode or its neighboring electrodes to reduce the threshold of stimulation.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: November 13, 2012
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Robert J. Greenberg, Richard Williamson
  • Patent number: 8301248
    Abstract: A patient's ejection fraction is maximized through simultaneous sensing and stimulating across multiple electrodes. In one exemplary embodiment, a catheter or lead having multiple electrodes connected to a pulse generator is used. The pulse generator provides individual current control of the stimulus applied to each electrode, and further includes the ability to sense intrinsic and evoked depolarization through multiple electrodes. In another exemplary embodiment, a multiplicity of individual implantable microstimulators, each having its own current source and/or sensor and electrodes, cooperate in concert to provide multi-site stimulation and sensing.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: October 30, 2012
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: James R. Thacker, Kelly H. McClure, Todd K. Whitehurst
  • Patent number: 8224431
    Abstract: Methods and apparatus for storing data records associated with a medical monitoring event in a data structure. An implanted device obtains data and stores the data in the data record in a first data structure that is age-based. Before an oldest data record is lost, the oldest data record may be stored in a second data structure that is priority index-based. The priority index may be determined by a severity level and may be further determined by associated factors. The implanted device may organize, off-load, report, and/or display a plurality of data records based on an associated priority index. Additionally, the implanted device may select a subset or composite of physiologic channels from the available physiologic channels based on a selection criterion.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: July 17, 2012
    Assignee: Medtronic, Inc.
    Inventor: Touby A. Drew
  • Patent number: 8214033
    Abstract: Exemplary systems, devices, and methods pertaining to cardiac related therapy and particularly to interferential cardiac preconditioning and depolarization are described. A cardiac arrhythmia is detected from electrogram data sensed from a patient's heart and a region of the heart affected by the cardiac arrhythmia is determined. The affected region is interferentially energized by multiple cycles of two concurrently delivered alternating currents which are offset in frequency.
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: July 3, 2012
    Assignee: Pacesetter, Inc.
    Inventors: Jay Snell, Mary Elizabeth Bush
  • Publication number: 20120078326
    Abstract: An electromedical device for the non-invasive reduction or removal of subcutaneous adipose tissue, comprising an energy source which provides a high-frequency alternating current, comprising at least two individual emitters which are fed by the energy source and which are designed to emit high-frequency electromagnetic waves into subcutaneous adipose tissue, and comprising a directivity control which is coupled with the individual emitters and which controls the individual emitters in such a way that, by direction and field concentration of the high-frequency electromagnetic waves emitted by the individual emitters, a total electromagnetic field with a desired field geometry can be produced in the subcutaneous adipose tissue.
    Type: Application
    Filed: September 29, 2011
    Publication date: March 29, 2012
    Applicant: Zimmer MedizinSysteme GmbH
    Inventor: Karlheinz Bussek
  • Publication number: 20110295341
    Abstract: Systems and methods for the delivery and monitoring of a medication, such as insulin, to a recipient are provided. An exemplary feature-rich system comprises an infusion pump with a control system for controlling medication delivery by the infusion pump and a bolus estimator for estimating an appropriate amount of medication for delivery by the control system with the infusion pump. Estimating the appropriate amount of medication for delivery is based upon one or more settings which each vary according to a setting profile. In other embodiments, the control system comprises a suspend function for temporarily suspending medication delivery by the infusion pump, an alarm profile function for programming a variable alarm volume of the alarm and a simplified menu for controlling the dual wave bolus delivery function.
    Type: Application
    Filed: August 5, 2011
    Publication date: December 1, 2011
    Applicant: MEDTRONIC MINIMED, INC.
    Inventors: Mark C. Estes, Leif N. Bowman, DeNetta Malave, Cary Dean Talbot
  • Patent number: 7971998
    Abstract: The present invention relates to an apparatus and a method for measuring a displacement in vivo in situ of an eye, along with a method of assessing of an eye condition. More particularly, the apparatus and method of the present invention permits measurements of a displacement of at least two points in proximity of an optic disc, in the eye of a patient. For doing so, the apparatus uses a probing unit, an analog/digital converter and an analyzer. The displacement measured may include a pulsatile displacement of the lamina cribrosa, so as to perform early assessment of an eye condition.
    Type: Grant
    Filed: November 14, 2007
    Date of Patent: July 5, 2011
    Assignee: RSEM, Limited Partnership
    Inventors: Mark Lesk, Marcelo Wajszilber, Tsuneyuki Ozaki
  • Patent number: 7974703
    Abstract: Techniques for shifting between two electrode combinations. An amplitude of a first electrode combination is incrementally decreased while an amplitude of a second, or subsequent, electrode combination is concurrently incrementally increased. Alternatively, an amplitude of the first electrode combination is maintained at a target amplitude level while the amplitude of the second electrode combination is incrementally increased. The stimulation pulses of the electrode combinations are delivered to the patient interleaved in time. In this manner, the invention provides for a smooth, gradual shift from a first electrode combination to a second electrode combination, allowing the patient to maintain a continual perception of stimulation. The shifting techniques described herein may be used during programming to shift between different electrode combinations to find an efficacious electrode combination.
    Type: Grant
    Filed: March 18, 2009
    Date of Patent: July 5, 2011
    Assignee: Medtronic, Inc.
    Inventors: Steven M. Goetz, Andrew H. Houchins, Jeffrey T. Keacher, Gary W. King, Kenneth T. Heruth, Roy L. Testerman, Michael T. Lee, Nathan A. Torgerson, Joseph J. Nolan
  • Patent number: 7957814
    Abstract: The disclosure is directed to techniques for shifting between two electrode combinations. An amplitude of a first electrode combination is incrementally decreased while an amplitude of a second, or subsequent, electrode combination is concurrently incrementally increased. Alternatively, an amplitude of the first electrode combination is maintained at a target amplitude level while the amplitude of the second electrode combination is incrementally increased. The stimulation pulses of the electrode combinations are delivered to the patient interleaved in time. In this manner, the invention provides for a smooth, gradual shift from a first electrode combination to a second electrode combination, allowing the patient to maintain a continual perception of stimulation. The shifting techniques described herein may be used during programming to shift between different electrode combinations to find an efficacious electrode combination.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: June 7, 2011
    Assignee: Medtronic, Inc.
    Inventors: Steven M. Goetz, Andrew H. Houchins, Jeffrey T. Keacher, Gary W. King, Kenneth T. Heruth, Roy L. Testerman, Michael T. Lee, Nathan A. Torgerson, Joseph J. Nolan
  • Publication number: 20110125225
    Abstract: New effective emergency non invasive pacing technique and apparatus is designed to improve the heart rate, cardiac output in patients during bradycardia. It also overcomes the existing disadvantages of unwanted transcutaneous muscular stimulation in the process of cardiac stimulation. This method uses interferential high frequency currents to selectively produce pulsed stimulus to the desirable area of myocardium is introduced.
    Type: Application
    Filed: August 12, 2008
    Publication date: May 26, 2011
    Inventor: Narayanan Lakshimanan
  • Publication number: 20100280573
    Abstract: A method of stimulating sensory nerves is disclosed that comprises the steps of providing an electrode plate with a pattern of needle-like (NL) electrodes and conductive plate (CP) electrodes disposed on a front face of the plate element, the NL electrodes being configured to apply electrical stimulation to cutaneous A?/C fibers, and the CP electrodes being configured to apply electrical stimulation to cutaneous A? fibers; mounting the electrode plate on a patient's skin with the front face in an abutting relationship with the patient's skin, the abutting relationship causing the NL electrodes to penetrate the epidermis of the patient's skin; and applying electrical stimulation to the patient's skin via the pattern of NL electrodes and CP electrodes, the electrical stimulation being applied so that A? fiber input from the CP electrodes overlaps in time at the patient's spinal cord and/or brain stem with A?/C fiber input from the NL electrodes.
    Type: Application
    Filed: May 7, 2010
    Publication date: November 4, 2010
    Applicant: Meagan Medical, Inc.
    Inventor: Jens Olaf Roe SCHOUENBORG
  • Patent number: 7787955
    Abstract: The muscle training apparatus includes: conductors to be mounted on a body of a user; an operation section for receiving an instruction from the user; a memory section for storing a current-and-frequency-correlation data which indicates a relationship between a magnitude of an electrical stimulation signal and a supply frequency of the electrical stimulation signal; a control section for determining the supply frequency based on the magnitude of the electrical stimulation signal input from the operation section, and the current-and-frequency-correlation data; and an electrical stimulation output section for generating the electrical stimulation signal based on the magnitude of the electrical stimulation signal and the supply frequency of the electrical stimulation signal which are instructed by the control section, and generating an interference wave by providing the electrical stimulation signal to the body of the user via the conductors.
    Type: Grant
    Filed: April 22, 2005
    Date of Patent: August 31, 2010
    Assignee: Ito Co., Ltd.
    Inventors: Atsumi Ohta, Nobuo Ogiwara
  • Publication number: 20100198314
    Abstract: Methods and devices for providing computerized adjustment to therapy parameters using real time and retrospective data processing is provided. Embodiments include receiving a respective data set from an infusion device and an analyte monitoring device for a predetermined time duration, user notification and reminder of the predetermined time duration, time synchronizing the received respective data set, detecting one or more marked data from the one or more respective data set received, establishing one or more filtering criteria to filter of retrospective or historical data based on certain condition, performing automated data analysis based on the detected one or more marked data or the data achieving certain predetermined condition to generate a modification to a therapy profile, generating and modifying rules for profile modification, and providing the generated modification to the therapy profile for reporting and transmission.
    Type: Application
    Filed: January 30, 2009
    Publication date: August 5, 2010
    Applicant: Abbott Diabetes Care, Inc.
    Inventor: Charles Wei
  • Patent number: 7689289
    Abstract: The locus of electrically excitable tissue where action potentials are induced can be controlled using the physiological principle of electrotonus. Substantially non-simultaneous first and second pulses are applied to first and second electrodes, respectively, to generate both first and second action potentials and first and second subthreshold potential areas, within the tissue. The locus within the tissue where additional action potentials are induced may be determined by a superposition of the first and second subthreshold areas according to the physiological principle of electrotonus. Superposition of the first and second subthreshold areas provides deep tissue suprathreshold potential areas of adjustable locus wherein additional action potentials are induced.
    Type: Grant
    Filed: March 22, 2006
    Date of Patent: March 30, 2010
    Assignee: Medtronic, Inc.
    Inventor: Gary W. King
  • Patent number: 7676270
    Abstract: A fixation device for holding stimulating electrodes in electrical contact with the wall of a portion of the gastrointestinal tract is provided. The fixation device includes an expandable member that fixes the electrodes in electrical contact with the gastrointestinal tract wall.
    Type: Grant
    Filed: November 16, 2005
    Date of Patent: March 9, 2010
    Assignee: IntraPace, Inc.
    Inventor: Mir A. Imran
  • Patent number: 7565202
    Abstract: The present invention is a system for mapping a high resolution image to a lower resolution electrode array and, by applying varying stimulus to neighboring electrodes, creating a perceived image greater in resolution than the electrode array. The invention is applicable to a wide range of neural stimulation devices including artificial vision and artificial hearing. By applying a sub-threshold stimulus to two neighboring electrodes where the sum of the stimuli is above the threshold of perception, a perception is created in neural tissue between the two electrodes. By adjusting the stimulus on neighboring electrodes, the location of stimulation can be altered. Further, noise can be applied to the stimulating electrode or its neighboring electrodes to reduce the threshold of stimulation.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: July 21, 2009
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Robert J. Greenberg, Richard Williamson
  • Patent number: 7519431
    Abstract: The disclosure is directed to techniques for shifting between two electrode combinations. An amplitude of a first electrode combination is incrementally decreased while an amplitude of a second, or subsequent, electrode combination is concurrently incrementally increased. Alternatively, an amplitude of the first electrode combination is maintained at a target amplitude level while the amplitude of the second electrode combination is incrementally increased. The stimulation pulses of the electrode combinations are delivered to the patient interleaved in time. In this manner, the invention provides for a smooth, gradual shift from a first electrode combination to a second electrode combination, allowing the patient to maintain a continual perception of stimulation. The shifting techniques described herein may be used during programming to shift between different electrode combinations to find an efficacious electrode combination.
    Type: Grant
    Filed: April 10, 2006
    Date of Patent: April 14, 2009
    Assignee: Medtronic, Inc.
    Inventors: Steven M. Goetz, Andrew H. Houchins, Jeffrey T. Keacher, Gary W. King, Kenneth T. Heruth, Roy L. Testerman, Michael T. Lee, Nathan A. Torgerson, Joseph J. Nolan
  • Patent number: 7291107
    Abstract: A system for recommending insulin bolus quantities to an insulin user includes a display unit and memory unit coupled to a control circuit with a user blood glucose target stored in the memory unit. The control circuit is programmed to receive the user's current blood glucose value, to determine and display via the display unit a recommended correction insulin bolus quantity if the current blood glucose value exceeds the blood glucose target, to compute a difference value as the current blood glucose value less the blood glucose target, and to produce a modified blood glucose target as a sum of the blood glucose target and the difference value for a lock-out time period if the difference value is positive. Additional correction insulin bolus quantities may be recommended during the lock-out time period if the user's current blood glucose value exceeds the modified blood glucose target.
    Type: Grant
    Filed: August 26, 2004
    Date of Patent: November 6, 2007
    Assignees: Roche Diagnostics Operations, Inc., Disetronic Licensing AG
    Inventors: Robert Hellwig, Stefan Weinert
  • Patent number: 7283877
    Abstract: A new method of recording and processing neural responses (“NR”) is provided, wherein the method does not assume a linear system response and does not assume a linear response at the interface between electrodes and tissue. The method of the present invention cancels out non-linearities and/or system hysteresis. Other artifacts such as system cross-talk between stimulation and recording circuits are also canceled out. The method provided uses at least two stimulating electrodes simultaneously in one recording step.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: October 16, 2007
    Assignee: Advanced Bionics Corporation
    Inventors: Leonid M Litvak, Edward H Overstreet
  • Patent number: 7133723
    Abstract: The cell enhancing device for an electrical pulse cosmetic meter, wherein the composite pulse generating device comprising an electrical pulse generating device, generating an electrical pulse sequence of a predetermined electrical pulse amplitude, wherein a frequency of said electrical pulse sequence is adjustable, a waveform adjuster, converting said electrical pulse sequence to a composite pulse sequence, and outputting said composite pulse sequence to a cosmetic head of said electrical pulse cosmetic meter. The present invention has the advantages of being small in size and light in weight. Furthermore, it greatly enhances circulation in skin structure of body, so as to achieve effective cosmetic results.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: November 7, 2006
    Assignee: Misty Li-Ming Chang
    Inventor: Eukki Qi Yu
  • Patent number: 7130696
    Abstract: A method of producing percutaneous electrode array is disclosed for applying therapeutic electrical energy to a treatment site in the body of a patient. The array comprises a plurality of electrode microstructures which are inserted into the epidermis, thereby overcoming the inherent electrical impedance of the outer skin layers and obviating the need to prepare the skin surface prior to an electro-therapy treatment. The array preferably includes an adhesion layer to help keep the electrode microstructures inserted into the epidermis during the duration of the therapeutic treatment, and temperature and condition monitoring devices to ensure proper treatment and enhance patient safety.
    Type: Grant
    Filed: October 4, 2004
    Date of Patent: October 31, 2006
    Assignee: Biowave Corporation
    Inventors: John Carter, Bradford Siff
  • Patent number: 7013179
    Abstract: A percutaneous electrode array is disclosed for applying therapeutic electrical energy to a treatment site in the body of a patient. The array comprises a plurality of electrode microstructures which are inserted into the epidermis, thereby overcoming the inherent electrical impedance of the outer skin layers and obviating the need to prepare the skin surface prior to an electro-therapy treatment. The array preferably includes an adhesion layer to help keep the electrode microstructures inserted into the epidermis during the duration of the therapeutic treatment, and temperature and condition monitoring devices to ensure proper treatment and enhance patient safety.
    Type: Grant
    Filed: June 10, 2003
    Date of Patent: March 14, 2006
    Assignee: Biowave Corporation
    Inventors: John Carter, Bradford Siff
  • Patent number: 6988005
    Abstract: A multi-functional portable electro-medical device that is capable of providing muscle stimulation and interferential current stimulation. The multi-functional portable electro-medical device includes a multitude of safety features which are designed to prevent injury to the user while at the same time to ensure that the portable power electro-medical device is easy to use. The portable electro-medical device can be programmed to impart any combination of wave therapy to the patient.
    Type: Grant
    Filed: April 29, 2002
    Date of Patent: January 17, 2006
    Assignee: International Rehabilitative Sciences, Inc.
    Inventors: Michael B. McGraw, William A. Rux, William J. Carroll, Richard M. Terrell, Randy Alan Murphy
  • Patent number: 6937905
    Abstract: A stimulator and a method for electrical stimulation of bone to promote osteogenesis is disclosed in which surface electrodes positioned around an incision site transmit an interferential current that has a base medium frequency alternating current between 1K-20 KHz. A digital signal processor generates a sine-wave-like waveform from a pulse generator which after further processing is used to generate two circuits for use in producing the interferential current. The effective area of stimulation is controlled by placement of electrodes and electrode orientation. Amplitude modulation of electrical circuits created at the electrode placements also augments the effective area of stimulation.
    Type: Grant
    Filed: August 1, 2003
    Date of Patent: August 30, 2005
    Assignee: International Rehabilitative Coion Sciences, Inc.
    Inventors: William J. Carroll, Michael B. McGraw, William A. Rux
  • Patent number: 6853863
    Abstract: An apparatus for providing therapeutic electric current to a treatment site of a patient is disclosed, which provides two oscillating or pulsing electric alternating currents, of frequencies which differ from each other by as little as 1 Hz and up to about 250 Hz, but each being of frequency at least about 1 KHz. The apparatus requires only one feed electrode adapted to feed the electric currents to selected feed sites on or beneath the epidermal or mucous surface of the patient, and only one return electrode adapted to be positioned on or beneath the epidermal or mucous surface of the patient, locally to the treatment site. The apparatus includes a feedback subsystem to detect impedance changes in the patient and accordingly adjust the output of the apparatus.
    Type: Grant
    Filed: March 10, 2003
    Date of Patent: February 8, 2005
    Assignee: Biowave Corporation
    Inventors: John Carter, Bradford Siff
  • Patent number: 6826429
    Abstract: An apparatus for treating patients using electrical interferential therapy is disclosed. The apparatus uses multiple electrodes to define multiple treatment channels, with each channel having a discrete frequency and an adjustable beat frequency between all or selected channel pairs. This adjustment can be done between treatment sessions or can be done during the treatment session by the technician or by the apparatus as programmed. The multiple treatment channels can be used on the same patient, or can be used by the same or a different technician to treat additional patient(s).
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: November 30, 2004
    Assignees: Dynatronics Corporation, Alan Neuromedical Technologies, LLC
    Inventors: Benjamin Glade Johnson, Donald Alan Rhodes
  • Patent number: 6792315
    Abstract: An apparatus for providing therapeutic electric current to a treatment site of a patient is disclosed, which provides two oscillating or pulsing electric alternating currents, of frequencies which differ from each other by as little as 1 Hz and up to about 250 Hz, but each being of frequency at least about 1 KHz. The apparatus requires only one feed electrode adapted to feed the electric currents to selected feed sites on or beneath the epidermal or mucous surface of the patient, and only one return electrode adapted to be positioned on or beneath the epidermal or mucous surface of the patient, locally to the treatment site. The apparatus includes a feedback subsystem to detect impedance changes in the patient and accordingly adjust the output of the apparatus.
    Type: Grant
    Filed: April 21, 2003
    Date of Patent: September 14, 2004
    Assignee: Biowave Corporation
    Inventors: John Carter, Bradford Siff
  • Patent number: 6760627
    Abstract: An electro-therapy apparatus and method for providing therapeutic electric current to a treatment site of a patient, having means for providing two oscillating or pulsing electric alternating currents, of frequencies which differ from each other by as little as 1 Hz and up to about 250 Hz, but each being of frequency at least about 1 KHz. The apparatus and method requires only one feed electrode adapted to feed the electric currents to selected feed sites on or beneath the epidermal or mucous surface of the patient, and only one return electrode adapted to be positioned on or beneath the epidermal or mucous surface of the patient, locally to the treatment site. The apparatus includes a feedback subsystem to detect impedance changes in the patient and accordingly adjust the output of the apparatus.
    Type: Grant
    Filed: March 10, 2003
    Date of Patent: July 6, 2004
    Assignee: Biowave Corporation
    Inventors: John Carter, Bradford Siff
  • Patent number: 6675046
    Abstract: A system and method is described for preferentially stimulating dorsal column fibers while avoiding stimulation of dorsal root fibers. The invention applies hyperpolarizing pre-pulses and depolarizing pre-pulses to neural tissue, such as spinal cord tissue, through a lead placed over the spinal cord having the electrodes arranged on a line approximately transverse to the axis of the spine. To increase the threshold needed to stimulate dorsal root fibers, the anodal pulse given by each lateral contact of the electrodes has to be preceded by a depolarizing pre-pulse and simultaneously, the central electrode contact gives a hyperpolarizing pre-pulse, thereby reducing the stimulation threshold for the dorsal column fibers to subsequent depolarizing pulses.
    Type: Grant
    Filed: May 7, 2002
    Date of Patent: January 6, 2004
    Assignee: Medtronic, Inc.
    Inventor: Jan Holsheimer
  • Patent number: 6564103
    Abstract: A system and method for performing multiple modes of electro-therapy with a portable electro-therapy device are disclosed. Preferably, the modes include an interferential mode, a pre-modulated interferential mode, a neuromuscular mode and a high volt pulse current mode. Additional protocols may be defined by combining or varying modes. The electro-therapy device uses a microprocessor to generate and control output signals. The microprocessor is contained within the housing of the electro-therapy device. The device includes a display and at least one keypad. The device also includes an electrode jack for attaching at least one pair of electrodes for outputting signals to a patient.
    Type: Grant
    Filed: December 1, 2000
    Date of Patent: May 13, 2003
    Assignee: VisionQuest Industries, Inc.
    Inventors: Wallace Ray Fischer, Raymond Charles Fischer
  • Patent number: 6512955
    Abstract: A system and method for generating high voltage, pulsed electrical stimulation to a patient for therapeutic treatment. The apparatus includes a voltage controlled pulse generator network that provides an output waveform including three monophasic pulses. This waveform is output to an electrode set including two active electrodes and one ground electrode. The triple pulse monophasic wave pattern is capable of reverse polarities. Each electrode in the electrode set generates independently variable intensities, while still using the common ground element. The voltage output of each active electrode is independently variable with respect to each other. The pulse generator network may be controlled using a processor, and in particular, a microprocessor, for example. A common control pulse is initially generated. The control pulse triggers dual trigger pulses. Each trigger pulse includes three monophasic pulses. These pulses may be spaced 100 microseconds apart in accordance with one embodiment of the invention.
    Type: Grant
    Filed: August 7, 2000
    Date of Patent: January 28, 2003
    Inventors: Thomas J. McEnany, Michael Carroll
  • Patent number: 6505078
    Abstract: The locus of electrically excitable tissue where action potentials are induced can be controlled using the physiological principle of electrotonus. In one embodiment, first and second pulses are applied to first and second electrodes, respectively, to generate first and second subthreshold potential areas, respectively, within the tissue. The locus within the tissue where action potentials are induced is determined by a superposition of the first and second subthreshold areas according to the physiological principle of electrotonus. In another embodiment, a two-dimensional array of electrodes are formed. The cathode may be positioned near the center of the two-dimensional array or may be left out. The first and second subthreshold areas may thereby be steered. An array of anodal rings may be used to contain the field of excitation.
    Type: Grant
    Filed: March 10, 2000
    Date of Patent: January 7, 2003
    Assignee: Medtronic, Inc.
    Inventors: Gary W. King, Robert Leinders, Greg Hrdlicka, Michael D. Baudino
  • Patent number: 6463330
    Abstract: A device for canceling unwanted excitation waves in an excitable tissue, particularly those causing cardiac tachyarrhythmias, which comprises circuitry for generating a unidirectional Device-Generated Excitation Wave (DGEW) in the tissue. The device comprises first and second stimulation electrodes, each fed by a power supply, which generate current impulses having magnitudes respectively lower and higher than the threshold level of the excitable tissue. The positions and activation timing of the electrodes are set so that the two impulses interact with each other only in one desired direction and every impulse except the desired DGEW decays.
    Type: Grant
    Filed: October 8, 1999
    Date of Patent: October 8, 2002
    Assignee: Ben-Gurion University of the Negev
    Inventors: Avinoam Rabinovitch, Eli Ovsyshcher
  • Publication number: 20020099425
    Abstract: An apparatus for treating patients using electrical interferential therapy is disclosed. The apparatus uses multiple electrodes to define multiple treatment channels, with each channel having a discrete frequency and an adjustable beat frequency between all or selected channel pairs. This adjustment can be done between treatment sessions or can be done during the treatment session by the technician or by the apparatus as programmed. The multiple treatment channels can be used on the same patient, or can be used by the same or a different technician to treat additional patient(s).
    Type: Application
    Filed: January 19, 2001
    Publication date: July 25, 2002
    Inventors: Benjamin Glade Johnson, Donald Alan Rhodes
  • Patent number: 6421566
    Abstract: A system and method is described for preferentially stimulating dorsal column fibers while avoiding stimulation of dorsal root fibers. The invention applies hyperpolarizing pre-pulses and depolarizing pre-pulses to neural tissue, such as spinal cord tissue, through a lead placed over the spinal cord having the electrodes arranged on a line approximately transverse to the axis of the spine. To increase the threshold needed to stimulate dorsal root fibers, the anodal pulse given by each lateral contact of the electrodes has to be preceded by a depolarizing pre-pulse and simultaneously, the central electrode contact gives a hyperpolarizing pre-pulse, thereby reducing the stimulation threshold for the dorsal column fibers to subsequent depolarizing pulses.
    Type: Grant
    Filed: June 12, 2000
    Date of Patent: July 16, 2002
    Assignee: Medtronic, Inc.
    Inventor: Jan Holsheimer
  • Patent number: 6393328
    Abstract: A multi-functional portable electro-medical device that is capable of providing muscle stimulation and interferential current stimulation. The multi-functional portable electro-medical device includes a multitude of safety features which are designed to prevent injury to the user while at the same time to ensure that the portable power electro-medical device is easy to use. The portable electro-medical device can be programmed to impart any combination of wave therapy to the patient.
    Type: Grant
    Filed: May 8, 2000
    Date of Patent: May 21, 2002
    Assignee: International Rehabilitative Sciences, Inc.
    Inventors: Michael B. McGraw, William A. Rux, William J. Carroll, Richard M. Terrell, Randy Alan Murphy
  • Patent number: 6122548
    Abstract: Undesirable cross-conduction between electrode pairs in a human-implantable dual channel neurostimulator is prevented. The first and second pairs of electrodes may, optionally, share a common electrode. The first electrode pair is stimulated and then recharged. Then, after a finite waiting period has elapsed, the second electrode pair is stimulated and then recharged. Then, after a finite waiting period, the process is repeated. A high impedance state is established across one of the electrode pairs while the other electrode pair is being stimulated and recharged. Such a high impedance state prevents current from flowing through one of the electrode pairs while the other electrode pair is being stimulated or recharged.
    Type: Grant
    Filed: July 7, 1999
    Date of Patent: September 19, 2000
    Assignee: Medtronic, Inc.
    Inventors: Warren Starkebaum, Mark T. Rise, Donald L. Hall, Marc T. Stein