Formed Inside Natural Blood Vessel Patents (Class 623/1.21)
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Patent number: 11724124Abstract: Systems and methods for restructure and stabilization of bones that provide an anti-microbial effect are disclosed herein. A device includes a delivery catheter having an inner void for passing at least one light sensitive liquid, and an inner lumen; an expandable member releasably engaging the distal end of the delivery catheter; at least one channel positioned in the expandable member; and a light conducting fiber sized to pass through the inner lumen of the delivery catheter and into the expandable member, wherein, when the light conducting fiber is in the at least one channel, the light conducting fiber is able to disperse light energy to provide an anti-microbial effect. When the light conducting fiber is in the expandable member, the light conducting fiber is able to disperse the light energy to initiate hardening of the light sensitive liquid within the expandable member to form a photodynamic implant.Type: GrantFiled: October 12, 2021Date of Patent: August 15, 2023Assignee: IlluminOss Medical, Inc.Inventors: Robert A. Rabiner, Daniel E. Rabiner, Gene P. DiPoto, Augustus C. Shanahan, Franklin D. Shuler
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Patent number: 11607310Abstract: In a representative embodiment, a method comprises implanting first and second inflatable bodies within an annulus of a native heart valve by securing the inflatable bodies to tissue of the native heart valve with sutures, and implanting a prosthetic heart valve between the inflatable bodies such that the prosthetic heart valve is retained within the annulus by the inflatable bodies.Type: GrantFiled: November 12, 2020Date of Patent: March 21, 2023Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: David M. Taylor, Alexander J. Siegel, Thomas V. Doherty, Christopher J. Olson, Yoon Hee Kwon
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Patent number: 10893964Abstract: The present disclosure describes implantable medical devices comprising covers, such as a balloon cover. Such devices can comprise a first layer of a porous polymeric material, such as ePTFE, surrounded by layers of a porous polymeric material having an imbibed elastomer, such as polyurethane. The cover can be used to assist in deployment of an expandable implant, such as a stent-graft, within the body of the patient.Type: GrantFiled: March 1, 2017Date of Patent: January 19, 2021Assignee: W. L. Gore & Associates, Inc.Inventors: Deenu G. Kanjickal, James J. Nickerson, Thomas G. Triebes
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Patent number: 10888443Abstract: A tack device for holding plaque against blood vessel walls in treating atherosclerotic occlusive disease is formed as a thin, annular band of durable, flexible material having a plurality of focal elevating elements on its outer annular periphery for holding loose plaque under a spring or other expansion force against a blood vessel wall. The focal elevating elements are designed to exert a holding force on a plaque position while minimizing the amount of material surface area in contact with the plaque or blood vessel wall and reducing the potential of friction with the intraluminal surface. This approach offers clinicians the ability to perform a minimally invasive post-angioplasty treatment and produce a stent-like result without using a stent.Type: GrantFiled: January 28, 2019Date of Patent: January 12, 2021Assignee: Intact Vascular, Inc.Inventors: Peter Schneider, Robert Giasolli
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Patent number: 10835403Abstract: The present disclosure describes implantable medical devices comprising covers, such as a balloon cover. Such devices can comprise a first layer of a porous polymeric material, such as ePTFE, surrounded by layers of a porous polymeric material having an imbibed elastomer, such as polyurethane. The cover can be used to assist in deployment of an expandable implant, such as a stent-graft, within the body of the patient.Type: GrantFiled: March 1, 2017Date of Patent: November 17, 2020Assignee: W. L. Gore & Associates, Inc.Inventors: Deenu G. Kanjickal, James J. Nickerson, Thomas G. Triebes
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Patent number: 10314593Abstract: An implant can include a single- or dual-layer braided body having a variable porosity. In a dual-layer body, first and second longitudinal sections, having respective first and second porosities, can be overlapped such that the first and second porosities overlap each other. The dual-layer construction can cumulatively provide a third porosity at a distal portion and a fourth porosity at a proximal portion. The third and fourth porosities can each be greater than each of the first and second porosities.Type: GrantFiled: September 23, 2015Date of Patent: June 11, 2019Assignee: Covidien LPInventors: Earl Bardsley, Richard Rhee
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Patent number: 10265204Abstract: Provided is a synthetic resin stent that has resistance to pressure externally applied from the radial direction while in an enlarged diameter state even when the synthetic resin fibers are thin. The synthetic resin stent comprises: a stent main section that is formed by synthetic resin fibers into a cylinder and that can deform from a reduced diameter state to an enlarged diameter state; and a restricting mechanism that keeps the stent main section in the enlarged diameter state by restricting the stent main section from reducing in diameter when in the enlarged diameter state. The synthetic resin stent preferably further comprises a diameter enlarging mechanism that is connected to the stent main section and that deforms the stent main section from a reduced diameter state to an enlarged diameter state.Type: GrantFiled: August 31, 2015Date of Patent: April 23, 2019Assignee: JMS CO., LTD.Inventors: Junichi Ide, Takashi Yamamoto, Shuji Fukutaki, Yuka Yamashina
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Patent number: 10188500Abstract: A scaffolded stent-graft includes a graft material comprising an inner surface and an outer surface. The inner surface defines a lumen within the graft material. The scaffolded stent-graft further includes a scaffold comprising a mesh coupled to the graft material at the outer surface. The scaffold is configured to promote tissue ingrowth therein. In this manner, the scaffold enhances tissue integration into the scaffolded stent-graft. The tissue integration enhances biological fixation of the scaffolded stent-graft in vessels minimizing the possibility of endoleaks and migration.Type: GrantFiled: February 12, 2016Date of Patent: January 29, 2019Assignee: Medtronic Vascular, Inc.Inventors: Keith Perkins, Jeffery Argentine, Matt Petruska, Samuel Robaina, Darren Galligan, Rajesh Radhakrishnan
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Patent number: 9227041Abstract: A medical device comprises a catheter with an expandable member, fibers extending from the outer surface of the expandable member, and therapeutic agent coated on the fibers or carried in the spaces between the fibers. Upon expansion of the expandable member, the therapeutic agent is delivered from the medical device. A surfactant may be coated on the fibers. A method of manufacturing comprises coating the outer surface of an expandable member with a metallic layer, coating the metallic layer with at least one polymeric layer, forming a plurality of holes in at least one polymeric layer, forming fibers in the holes, and removing at least one polymeric layer.Type: GrantFiled: April 8, 2011Date of Patent: January 5, 2016Assignee: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Jan Weber, John T. Clarke, Aiden Flanagan
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Patent number: 9192490Abstract: There is disclosed a method for maintaining a patent paranasal sinus ostium. In an embodiment, the method includes delivering a tubular element in an insertion state to the sinus ostium. The tubular element includes a proximal end, a distal end, and a center region between the proximal end and distal end. The method includes expanding the tubular element from the insertion state to a deployment state when located in the sinus ostium. In the deployment state, the center region confronts the sinus ostium with an outward radial force.Type: GrantFiled: September 25, 2014Date of Patent: November 24, 2015Assignee: Audubon Technologies, LLCInventors: Edward J. Hepworth, Corey B. Kashiwa, Steven P. Tyrrell
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Publication number: 20150142094Abstract: Deflection devices, systems, and methods for the prevention of stroke. Devices hereof comprise an extension portion and an anchor portion, both of which are configured to prevent the device from advancing into the artery extending from the aortic arch in which the device may be positioned. Additionally, a retrieval system is provided, the system comprising a sleeve catheter and a retrieval device slidably disposed therein. The distal end of the retrieval device comprises one or more attachment portions configured to engage at least a portion of the anchor portion of a device positioned within an artery extending from the aortic arch.Type: ApplicationFiled: November 18, 2014Publication date: May 21, 2015Inventors: Ghassan S. Kassab, Hyo Won Choi, Jose A. Navia, SR.
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Patent number: 8951298Abstract: A multi-component endovascular stent-graft system (10) includes a body portion (16), which includes a plurality of stent-grafts (20), which include: (a) respective stent members (22), which are shaped, when the stent-grafts (20) are in respective radially-expanded states, so as to define respective tubes, each of which is circumferentially complete at at least one longitudinal location therealong; and (b) respective graft members (24), which circumscribe respective circumferential arcs (40) of the respective stent members (22). The circumferential arcs (40) have respective extents that are less than entire circumferences of the respective stent members (22) at least partially along respective axial lengths of the stent members (22).Type: GrantFiled: June 19, 2012Date of Patent: February 10, 2015Assignee: Endospan Ltd.Inventor: Alon Shalev
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Patent number: 8911491Abstract: A stent graft extends in a flow lumen to span a defective portion of the flow lumen and seal the defective portion from further blood contact. The stent graft includes a pair of apertures, from which extensions project into the renal arteries to seal the passage of blood into the renal arteries from the abnormality. The apertures are larger than the opening of the renal arteries, such that the apertures need not be centered with the renal arteries to enable placement of the extensions. The aperture opening and side branch extensions contain hook and loop structures to provide a variably positionable seal of the aperture opening.Type: GrantFiled: September 2, 2005Date of Patent: December 16, 2014Assignee: Medtronic Vascular, Inc.Inventors: Curtis Hanson, Scott Cook, Joseph Lessar
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Patent number: 8906084Abstract: Embodiments provide methods and systems for treating aneurysms using filling structures filled with a curable medium. An embodiment of a method comprises positioning at least one double-walled filling structure across the aneurysm and filling the structure(s) with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device while and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint. The medium is hardened while the lumen remains supported by the balloon. The balloon is then removed after the medium hardens.Type: GrantFiled: January 7, 2010Date of Patent: December 9, 2014Assignee: Nellix, Inc.Inventors: Michael A. Evans, Gwendolyn A. Watanabe, Amy Lee, Steven L. Herbowy
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Patent number: 8859934Abstract: A method of removing slag formed during laser cutting a hypotube may include flowing cooling gas into a laser nozzle, directing flow of the cooling gas onto an external surface of the hypotube, and injecting cooling fluid into an inner lumen of the hypotube at a velocity. Flowing the cooling gas and injecting the cooling fluid may at least partially remove slag from the external surface of the hypotube.Type: GrantFiled: March 25, 2014Date of Patent: October 14, 2014Assignee: Insera Therapeutics, Inc.Inventors: Vallabh Janardhan, Vikram Janardhan
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Publication number: 20140277385Abstract: A method for forming a material in an in situ medical device by initiating polymerization of water soluble polymer precursors in an aqueous solution during or after transport of the polymerizable solution from its storage container to a space inside the in situ medical device is described. The stored aqueous solution with water soluble precursors lacks a free radical initiator which, in a powder form, is introduced into the aqueous solution during or after its transport into the space inside the in situ medical device. This storage and delivery system provides greater stability to the stored aqueous solution, allowing it to be stored at ambient temperature and providing extended shelf life over the solutions used in existing in situ polymerization systems. The flexibility to store and deliver/transport only one aqueous solution, instead of requiring the use of two different solutions, is also a benefit.Type: ApplicationFiled: March 7, 2014Publication date: September 18, 2014Applicant: Endologix, Inc.Inventors: Charles Bankert, Paolo Mendoza, Stefan Schreck
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Patent number: 8814928Abstract: An apparatus for repairing an aneurysm comprises a device having an inner graft tube and an inflatable outer balloon attached to an outer surface of the inner graft tube, and an inflatable deployment balloon. The inner graft tube is expandable within an artery to form a seal with the arterial wall above and/or below an aneurysm. The outer balloon is inflatable within the aneurysm with a rapidly settable substance to fill the aneurysm and support the device. The deployment balloon has an uninflated condition to fit within the inner graft tube and is inflatable within the inner graft tube to expand the inner graft tube within the artery and to maintain the inner graft tube expanded within the artery during inflation of the outer balloon.Type: GrantFiled: November 12, 2009Date of Patent: August 26, 2014Assignee: Vortex Innovation LimitedInventor: Marie Therese Robin
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Patent number: 8747345Abstract: A bypass provided by a bypass conduit disposed in a vessel which is collateral to an occluded vessel. The bypass conduit comprises a helical wire body having a plurality of connectors connecting adjacent turns of the helical body.Type: GrantFiled: April 28, 2011Date of Patent: June 10, 2014Assignee: Vanderbilt UniversityInventor: Joseph G Salloum
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Patent number: 8641746Abstract: Apparatus and methods for delivering stents and other prostheses to body lumens include a prosthesis forming and deploying mechanism carried at the distal end of a catheter shaft. The mechanism is adapted to form and deploy prostheses of a variable length, and to form and deploy multiple prostheses during a single interventional procedure.Type: GrantFiled: May 31, 2005Date of Patent: February 4, 2014Assignee: J.W. Medical Systems Ltd.Inventors: Bernard Andreas, Craig Welk, David Sanderson
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Publication number: 20130211500Abstract: Disclosed are liquid cast biodegradable arterial stents and methods for preparing liquid cast biodegradable arterial stents. The typically includes a biodegradable polymer and may include an agent for treating neointimal hyperplasia.Type: ApplicationFiled: April 14, 2011Publication date: August 15, 2013Applicant: NORTHWESTERN UNIVERSITYInventors: Melina R. Kibbe, Guillermo A. Ameer
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Publication number: 20130204351Abstract: The present invention provides methods and apparatus for the endoluminal positioning of an intraluminal prosthesis at a target location within a body lumen. The device may comprise a porous, multi-layer prosthesis that can include several different tubular mesh components such as an everted tubular component, an tubular component that expands to various different sizes, a bifurcated tubular component, and a tubular component with an undulating expanded shape, among others. Various components can have different densities or pore sizes and can be overlaid on each other to selectively block different regions of a vessel.Type: ApplicationFiled: February 4, 2013Publication date: August 8, 2013Applicant: Inceptus Medical LLCInventor: Inceptus Medical LLC
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Patent number: 8479742Abstract: Medical devices and related methods are disclosed for delivering an implant into the body of a patient. The devices include a damping assembly having an internal chamber with a varying inner diameter, and a piston slideably disposed therein. The piston is operably connected with a catheter portion such that movement of the piston is associated with concurrent movement of the catheter for implant delivery. The varying inner diameter of the damping assembly results in a decrease in damping force during implant delivery, thus providing a substantially constant velocity of implant delivery.Type: GrantFiled: February 28, 2011Date of Patent: July 9, 2013Assignee: Hologic, Inc.Inventor: Matthew LaPlaca
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Patent number: 8465436Abstract: An implant centering system includes a sensor connected to a hollow cylindrical anchor via at least two struts. The hollow cylindrical anchor is transformable between a radially compressed configuration for delivery and a radially expanded configuration for lodging against a vessel wall. The struts longitudinally relocate the sensor between a first position in which the sensor is longitudinally spaced apart from the radially compressed anchor, and a second position in which the sensor is at least partially within a lumen of the radially expanded anchor and radially centered within vessel. In one embodiment, the struts are heat-set into a curved configuration and an externally applied force longitudinally relocates the sensor until the struts lock over center into their heat-set configuration. In another embodiment, radial expansion of the anchor longitudinally relocates the sensor without an externally applied force.Type: GrantFiled: April 27, 2010Date of Patent: June 18, 2013Assignee: Medtronic Vascular, Inc.Inventor: Erik Griswold
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Patent number: 8460357Abstract: Apparatus and methods for delivering stents and other prostheses to body lumens include a prosthesis forming and deploying mechanism carried at the distal end of a catheter shaft. The mechanism is adapted to form and deploy prostheses of a variable length, and to form and deploy multiple prostheses during a single interventional procedure.Type: GrantFiled: May 31, 2005Date of Patent: June 11, 2013Assignee: J.W. Medical Systems Ltd.Inventors: Michael C. McGarry, Craig Welk
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Patent number: 8366764Abstract: By a contrast means contained in an inventive stent which has a greater permeability for x-radiation features than the body tissue surrounding the stent in a relevant body conduit, this stent can be clearly detected in its position on an x-ray image of the relevant body conduit while at the same time exhibiting good biological compatibility; a gas, especially one contained in cavities of the stent is provided as a contrast means. The inventive production method for this stent with the aid of a catheter embodied specially for the purpose enables the production of the stent from a malleable polymer mass in the relevant body conduit so that the stent is adapted especially precisely to the shape of the relevant body conduit.Type: GrantFiled: November 7, 2008Date of Patent: February 5, 2013Assignee: Siemens AktiengesellschaftInventor: Mathias Hörnig
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Patent number: 8292947Abstract: In order to create a stent, which despite being simple to guide in the relevant body conduit allows flexible adaptability to the body conduit in a simple manner while avoiding undesirably high expansion forces on the wall of the body conduit, in accordance with the invention a catheter is provided, with an essentially tubular filling area surrounding the part of the catheter which can be introduced into the body conduit, which can be filled with a plastic mass which forms the stent by a process of hardening; there is provision for positioning the filling area at the position intended for the stent in the body conduit, for hardening the plastic mass in the filling area, for creating the stent and for removing the catheter from the body conduit with the stent remaining in the body conduit.Type: GrantFiled: May 25, 2006Date of Patent: October 23, 2012Assignee: Siemens AktiengesellschaftInventor: Mathias Hörnig
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Publication number: 20120265287Abstract: Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms are disclosed. The systems include an insertable medical device and an in-situ forming foam that is formed from a polymer that reacts in an aqueous environment. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.Type: ApplicationFiled: June 25, 2012Publication date: October 18, 2012Applicant: Arsenal Medical, Inc.Inventors: Upma Sharma, Gregory Zugates, Rany Busold, Toby Freyman
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Publication number: 20120245674Abstract: A vascular remodeling device is provided. The device includes an anchor portion, sized for deployment in a blood vessel, that is radially expandable from a collapsed state to an expanded state. The device also includes a distal portion that is sized for deployment in a blood vessel. The distal portion is radially expandable from a collapsed state to an expanded state and, in some embodiments, has a distal face that is sufficiently occlusive in the distal-to-proximal direction to perform a therapeutic blocking function at an aneurysm. Some embodiments have an intermediate portion that connects a distal end of the anchor portion and a proximal end of the distal portion, and in some embodiments, the anchor portion and distal portion are able to pivot relative to each other at or near the intermediate portion.Type: ApplicationFiled: March 23, 2012Publication date: September 27, 2012Applicant: TYCO HEALTHCARE GROUP LPInventors: Masoud Molaei, Evan David Epstein, Gabriel Francis Wilgus Newell, Quang Tran
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Patent number: 8206433Abstract: A stent is described that is capable of expanding and thereafter recoiling to its initial coiled state within a biliary duct. A delivery system is utilized to deploy the stent in its natural coiled state into a targeted site of an occluded biliary duct. A balloon from the delivery system is positioned within a lumen defined by the inner coiled arm of the stent. The inflation of a balloon from the delivery system causes the inner coiled arm to radially move outward and engage the outer coiled arm to form an expanded stent. The expanded stent can revert back to its recoiled state by deploying a balloon through a lumen of the expanded stent. Inflation of the balloon disengages the inner coiled arm from the outer coiled arm thereby collapsing the inner coiled arm radially outward and onto the outer coiled arm to form a recoiled stent. The recoiled stent can be removed from the biliary duct.Type: GrantFiled: February 28, 2006Date of Patent: June 26, 2012Assignee: Cook Medical Technologies LLCInventor: Brian K. Rucker
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Patent number: 8044137Abstract: Certain embodiments of the invention include forming a material in situ by introducing into a space within a patient a water soluble polymer precursor of at least about 10,000 molecular weight solubilized in a flowable aqueous solution. Functional groups on the polymer precursor undergo covalent bonding in situ to form a solid and nonbiodegradable material having a swellability less than about 20% v/v and a Young's modulus of at least about 100 kPa within about 30 seconds to about 30 minutes of initiating a chemical reaction of the functional groups to form the solid material.Type: GrantFiled: December 16, 2010Date of Patent: October 25, 2011Assignee: Incept LLCInventors: Farhad Khosravi, James Dreher
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Patent number: 8029556Abstract: The present disclosure concerns embodiments of a reshaping apparatus and methods for restoring the conical shape of a dilated heart ventricle, or at least reshaping the ventricle to a more conical shape to counter the effects of dilation, thereby improving pumping efficiency. In an exemplary embodiment, a reshaping apparatus comprises an implantable body that can be delivered to a dilated left ventricle via the patient's vasculature in a minimally-invasive procedure. When deployed inside the left ventricle, the body is adapted to apply a longitudinal (downward) force against the inner surface of the left ventricle that causes the ventricle to distend or elongate downwardly relative to the base of the heart so as to at least partially restore the conical shape of the heart. In other embodiments, one or more tension members can be secured to heart tissue inside a heart chamber or on the outside of the heart and placed in tension to reshape the geometry of the heart.Type: GrantFiled: April 2, 2007Date of Patent: October 4, 2011Assignee: Edwards Lifesciences CorporationInventor: Stanton J. Rowe
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Patent number: 7872068Abstract: Certain embodiments of the invention include forming a material in situ by introducing into a space within a patient a water soluble polymer precursor of at least about 10,000 molecular weight solubilized in a flowable aqueous solution. Functional groups on the polymer precursor undergo covalent bonding in situ to form a solid and nonbiodegradable material having a swellability less than about 20% v/v and a Young's modulus of at least about 100 kPa within about 30 seconds to about 30 minutes of initiating a chemical reaction of the functional groups to form the solid material.Type: GrantFiled: May 30, 2006Date of Patent: January 18, 2011Assignee: Incept LLCInventors: Farhad Khosravi, James Dreher
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Publication number: 20100331947Abstract: A medical device comprising a compartment capable of receiving and holding a substance in a liquid form is disclosed. The compartment is inflatable from a deflated state to an inflated state, such that when the compartment is in the deflated state, the outer wall of the membrane is substantially impermeable to the substance, and when the compartment is in the inflated state, the substance is allowed to permeate through the outer wall.Type: ApplicationFiled: February 16, 2006Publication date: December 30, 2010Inventors: Alon Shalev, Alexander Dubson
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Patent number: 7857766Abstract: A system and method that minimizes plaque accumulation on a stent and thereby restenosis that could require a subsequent invasive medical procedure following implantation of the stent in a patient. A plurality of electrically-powered, biocompatible devices, implantable via injection, are positioned within the patient proximate to the stent and under control of a externally-placed controller are commanded to emit ultrasonic waves corresponding to the mechanical resonance of the stent. By controlling the frequency and the relative phases of the ultrasonic waves, the accumulation of plaque on the stent can thus be minimized.Type: GrantFiled: June 20, 2005Date of Patent: December 28, 2010Assignee: Alfred E. Mann Foundation for Scientific ResearchInventors: Brian J. Lasater, Lee J. Mandell
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Patent number: 7857748Abstract: Methods of manufacture of endoprostheses comprising one or more photocurable materials are disclosed. The endoprostheses may comprise regions wherein the photocurable materials are selectively disposed about the endoprosthesis and are cured according to desired parameters to achieve varying desired properties. Photolithographic masking material may be selectively disposed about an inflatable balloon and exposed to a radiation emitting catheter.Type: GrantFiled: October 19, 2006Date of Patent: December 28, 2010Assignee: Syne Cor, LLCInventors: Michael S. Williams, Kevin D. Holbrook, Richard A. Glenn, Jeffrey A. Smith, Joseph M. DeSimone
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Patent number: 7803178Abstract: The present invention provides inflatable porous implants, such as grafts, stent-grafts, and bladders, as well as methods and kits for drug delivery. In particular, the grafts and stent-grafts of the present invention provide for the delivery of a therapeutic agent into a flow conduit in the body. The inflatable porous implants provide for direct delivery of larger, more precise dosages of drugs over longer administration periods into the body. Moreover, these inflatable porous implants are often flexible when inserted and have a low profile delivery configuration for easy placement. The implants of the present invention further provide a mechanical or structural function in addition to drug delivery in a single integrated structure.Type: GrantFiled: January 30, 2004Date of Patent: September 28, 2010Assignee: TriVascular, Inc.Inventors: Robert G. Whirley, James M. Shapiro
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Patent number: 7749265Abstract: A radio frequency antenna is provided for use with a medical device for implantation into an animal. The antenna comprises a coil formed by a wire that includes a core formed of a shape-memory material with an electrically conductive first layer applied to an outer surface of the core. A second layer, of an electrically insulating and biologically compatible material, extends around the first layer. If necessary to reduce friction a lubricant is place between the first and second layers. If second layer is formed of porous material or a non-biological compatible material, a biological compatible outer layer surrounds the second layer thereby providing a barrier that is impermeable to body fluids of the animal.Type: GrantFiled: October 5, 2005Date of Patent: July 6, 2010Assignee: Kenergy, Inc.Inventors: Stephen Denker, Cherik Bulkes, Arthur J. Beutler
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Patent number: 7704276Abstract: A woven tubular endoprosthesis comprising means for locking the endoprosthesis in a deployed configuration is disclosed. The means for locking the endoprosthesis may comprise locking protrusions, notches, a chemical bond, a curable bond, or other mechanism. The woven fibers comprising the endoprosthesis may be hollow and comprise circumferentially oriented polymeric chains, and may be filled with a curable material. A method of treatment using an endoprosthesis according to the invention is also disclosed.Type: GrantFiled: September 30, 2006Date of Patent: April 27, 2010Assignee: SyneCor, LLCInventors: Michael S. Williams, Richard A. Glenn, Jeffrey A. Smith, Kevin D. Holbrook, Joseph M. DeSimone
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Patent number: 7682383Abstract: A device for repairing an aneurysm by deployment within the aneurysm comprises a graft tube, at least part thereof having an inflatable wall whereby the tube can be deployed in an artery and inflated to grip at least part of the arterial wall.Type: GrantFiled: June 17, 2002Date of Patent: March 23, 2010Inventor: Marie Therese Robin
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Patent number: 7615046Abstract: A urological medical system for performing a controlled hydrodistention of the urinary bladder for treating a bladder dysfunction problem comprised of a programmed CPU with associated computer equipment for facilitating an automatic control of a treatment procedure to be performed on a patient, a saline solution warmer, a saline solution pump, a four-way catheter wherein a channel is provided for monitoring the pressure within the bladder during the procedure, a syringe for infusing a medicine through the catheter and a strapping device to secure the syringe and to slidingly engage the catheter to a leg of the patient. Desired parameters are monitored during the procedure and a desired pressure is maintained in the bladder for a predetermined time to perform the controlled hydrodistention of the urinary bladder.Type: GrantFiled: October 25, 2006Date of Patent: November 10, 2009Inventor: Sobhy Shehata
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Patent number: 7611887Abstract: The invention concerns a micro-muscle designed to be immersed in a biological liquid, comprising a deformable chamber whereof one portion at least consists of a semipermeable membrane, said chamber containing a solution capable of osmotic activity. The solution is preferably activated by a product to be injected into the biological liquid.Type: GrantFiled: July 17, 2002Date of Patent: November 3, 2009Assignee: Universite Joseph FourierInventors: Philippe Cinquin, Olivier Cinquin, Denis Favier, Laurent Orgeas, Matthieu Pecher, Sonia Pujol
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Patent number: 7530988Abstract: Aneurysms are treated by filling a double-walled filling structure with a curable medium. The structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. The filling structures are preferably used in pairs for providing flow into the iliac arteries when treating abdominal aortic aneurysm.Type: GrantFiled: July 22, 2005Date of Patent: May 12, 2009Assignee: Nellix, Inc.Inventors: Michael A. Evans, Thomas Howell, Gwendolyn A. Watanabe, Bhupendra Shah, James McKinley
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Publication number: 20080312733Abstract: An implantable, radially distensible stent includes a plurality of helically wound elongate members. The members include an overlapping portion having a longitudinal extent, opposed and convexly rounded sides defining a width of the members and opposed luminal and exterior surfaces. The members include shape memory polymer. The side of one elongate member slidingly overlaps the side of an adjacent elongate member to form a self-supporting wall structure of a stent. The stent wall is self-supporting without other support structure incorporated into or abutting the elongate members. Further, the shape memory polymer may comprise a biodegradable or bioabsorbable elements.Type: ApplicationFiled: June 10, 2008Publication date: December 18, 2008Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventor: Gary Jordan
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Publication number: 20080294237Abstract: Methods and systems for preventing aneurysm rupture and reducing the risk of migration and endoleak are disclosed. Specifically, an inflatable liner is applied directly to treat the interior of the aneurysm site. Also disclosed are methods to deliver the inflatable liner directly to treatment sites.Type: ApplicationFiled: February 26, 2008Publication date: November 27, 2008Inventor: Jack Fa-De Chu
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Publication number: 20080146489Abstract: The present invention relates to the regional delivery of therapeutic agents for the treatment of vascular diseases wherein regional delivery refers to delivery of a therapeutically effective amount of the therapeutic agent to an area of the vessel that includes not only afflicted tissue but non-afflicted tissue at the periphery of the afflicted tissue as well.Type: ApplicationFiled: December 15, 2006Publication date: June 19, 2008Inventors: Stephen D. Pacetti, Paul M. Consigny, Ronald W. Heil, Florian Niklas Ludwig, Dariush Davalian, Li Zhao, Irina Astafieva, Jinping Wan, Fozan El-Nounou, Katsuyuki Murase, Syed F.A. Hossainy, Rachel Bright, Jeffrey Ellis
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Publication number: 20070282366Abstract: Certain embodiments of the invention include forming a material in situ by introducing into a space within a patient a water soluble polymer precursor of at least about 10,000 molecular weight solubilized in a flowable aqueous solution. Functional groups on the polymer precursor undergo covalent bonding in situ to form a solid and nonbiodegradable material having a swellability less than about 20% v/v and a Young's modulus of at least about 100 kPa within about 30 seconds to about 30 minutes of initiating a chemical reaction of the functional groups to form the solid material.Type: ApplicationFiled: May 30, 2006Publication date: December 6, 2007Inventors: Farhad Khosravi, James Dreher
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Patent number: 7198637Abstract: The invention provides a method of manufacturing a system for treating a vascular condition. A catheter including an inflatable balloon is provided. A stent is positioned over the balloon. An adhesive material is applied between an inner surface of the stent and an outer surface of the balloon. The adhesive material is heated to above a melting point of the adhesive material. The adhesive material is cooled to below a melting point of the adhesive material to provide an adhesive bond that retains the stent to the catheter during vascular delivery, wherein the stent is released from the balloon following inflation and deflation of the balloon at a treatment site.Type: GrantFiled: April 21, 2003Date of Patent: April 3, 2007Assignee: Medtronic Vascular, Inc.Inventors: Susheel R. Deshmukh, Kaushik A. Patel, Ronan Rogers
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Patent number: 7141061Abstract: Novel endoprostheses comprising one or more photocurable materials are disclosed. Said endoprostheses may comprise regions wherein said photocurable materials are selectively disposed about said endoprosthesis and are cured according to desired parameters to achieve varying desired properties. Said properties may include but are not limited to cross-linking density, material density, modulus of elasticity, rate of erosion, extensibility, compressibility, mechanical strength, tensile strength, crystallinity, diffusion coefficient, and permeability.Type: GrantFiled: January 15, 2003Date of Patent: November 28, 2006Assignee: SyneCor, LLCInventors: Michael S. Williams, Kevin D. Holbrook, Richard A. Glenn, Jeffrey A. Smith, Joseph M. DeSimone
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Patent number: 7108715Abstract: A graft (1) which is in the form of an inflatable member adapted to be formed into a predetermined and/or selected shape when deployed in situ by filling with a filler material (6) which can be made rigid in situ and deployed on a balloon catheter (12). The deployment balloon (13) is formed from a non-compliant material.Type: GrantFiled: October 24, 2002Date of Patent: September 19, 2006Assignees: Cook Incorporated, William A. Cook Australia Pty Ltd.Inventors: Michael Lawrence-Brown, Kurt Liffman, David Ernest Hartley
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Patent number: 7008446Abstract: A prosthesis for insertion into a body passage is disclosed. The prosthesis includes a plastic or polymer base material which is compatible with living tissue and which possesses a memory of a predetermined configuration. The base material further has a glass transition temperature at which the prosthesis can be molded intravascularly from the predetermined configuration to a larger-radius implant configuration, which is sized and shaped to conform to an internal anatomy of the body passage to expand a narrow segment of or to occlude an opening of an out pouch of the body passage. The glass transition temperature is greater than a temperature of the body passage so that the prosthesis after being molded can be allowed to cool to the temperature of the body passage.Type: GrantFiled: August 19, 2002Date of Patent: March 7, 2006Inventors: James Peter Amis, Hoi Sang U