Formed Inside Natural Blood Vessel Patents (Class 623/1.21)
  • Patent number: 10314593
    Abstract: An implant can include a single- or dual-layer braided body having a variable porosity. In a dual-layer body, first and second longitudinal sections, having respective first and second porosities, can be overlapped such that the first and second porosities overlap each other. The dual-layer construction can cumulatively provide a third porosity at a distal portion and a fourth porosity at a proximal portion. The third and fourth porosities can each be greater than each of the first and second porosities.
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: June 11, 2019
    Assignee: Covidien LP
    Inventors: Earl Bardsley, Richard Rhee
  • Patent number: 10265204
    Abstract: Provided is a synthetic resin stent that has resistance to pressure externally applied from the radial direction while in an enlarged diameter state even when the synthetic resin fibers are thin. The synthetic resin stent comprises: a stent main section that is formed by synthetic resin fibers into a cylinder and that can deform from a reduced diameter state to an enlarged diameter state; and a restricting mechanism that keeps the stent main section in the enlarged diameter state by restricting the stent main section from reducing in diameter when in the enlarged diameter state. The synthetic resin stent preferably further comprises a diameter enlarging mechanism that is connected to the stent main section and that deforms the stent main section from a reduced diameter state to an enlarged diameter state.
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: April 23, 2019
    Assignee: JMS CO., LTD.
    Inventors: Junichi Ide, Takashi Yamamoto, Shuji Fukutaki, Yuka Yamashina
  • Patent number: 10188500
    Abstract: A scaffolded stent-graft includes a graft material comprising an inner surface and an outer surface. The inner surface defines a lumen within the graft material. The scaffolded stent-graft further includes a scaffold comprising a mesh coupled to the graft material at the outer surface. The scaffold is configured to promote tissue ingrowth therein. In this manner, the scaffold enhances tissue integration into the scaffolded stent-graft. The tissue integration enhances biological fixation of the scaffolded stent-graft in vessels minimizing the possibility of endoleaks and migration.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: January 29, 2019
    Assignee: Medtronic Vascular, Inc.
    Inventors: Keith Perkins, Jeffery Argentine, Matt Petruska, Samuel Robaina, Darren Galligan, Rajesh Radhakrishnan
  • Patent number: 9227041
    Abstract: A medical device comprises a catheter with an expandable member, fibers extending from the outer surface of the expandable member, and therapeutic agent coated on the fibers or carried in the spaces between the fibers. Upon expansion of the expandable member, the therapeutic agent is delivered from the medical device. A surfactant may be coated on the fibers. A method of manufacturing comprises coating the outer surface of an expandable member with a metallic layer, coating the metallic layer with at least one polymeric layer, forming a plurality of holes in at least one polymeric layer, forming fibers in the holes, and removing at least one polymeric layer.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: January 5, 2016
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Jan Weber, John T. Clarke, Aiden Flanagan
  • Patent number: 9192490
    Abstract: There is disclosed a method for maintaining a patent paranasal sinus ostium. In an embodiment, the method includes delivering a tubular element in an insertion state to the sinus ostium. The tubular element includes a proximal end, a distal end, and a center region between the proximal end and distal end. The method includes expanding the tubular element from the insertion state to a deployment state when located in the sinus ostium. In the deployment state, the center region confronts the sinus ostium with an outward radial force.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: November 24, 2015
    Assignee: Audubon Technologies, LLC
    Inventors: Edward J. Hepworth, Corey B. Kashiwa, Steven P. Tyrrell
  • Publication number: 20150142094
    Abstract: Deflection devices, systems, and methods for the prevention of stroke. Devices hereof comprise an extension portion and an anchor portion, both of which are configured to prevent the device from advancing into the artery extending from the aortic arch in which the device may be positioned. Additionally, a retrieval system is provided, the system comprising a sleeve catheter and a retrieval device slidably disposed therein. The distal end of the retrieval device comprises one or more attachment portions configured to engage at least a portion of the anchor portion of a device positioned within an artery extending from the aortic arch.
    Type: Application
    Filed: November 18, 2014
    Publication date: May 21, 2015
    Inventors: Ghassan S. Kassab, Hyo Won Choi, Jose A. Navia, SR.
  • Patent number: 8951298
    Abstract: A multi-component endovascular stent-graft system (10) includes a body portion (16), which includes a plurality of stent-grafts (20), which include: (a) respective stent members (22), which are shaped, when the stent-grafts (20) are in respective radially-expanded states, so as to define respective tubes, each of which is circumferentially complete at at least one longitudinal location therealong; and (b) respective graft members (24), which circumscribe respective circumferential arcs (40) of the respective stent members (22). The circumferential arcs (40) have respective extents that are less than entire circumferences of the respective stent members (22) at least partially along respective axial lengths of the stent members (22).
    Type: Grant
    Filed: June 19, 2012
    Date of Patent: February 10, 2015
    Assignee: Endospan Ltd.
    Inventor: Alon Shalev
  • Patent number: 8911491
    Abstract: A stent graft extends in a flow lumen to span a defective portion of the flow lumen and seal the defective portion from further blood contact. The stent graft includes a pair of apertures, from which extensions project into the renal arteries to seal the passage of blood into the renal arteries from the abnormality. The apertures are larger than the opening of the renal arteries, such that the apertures need not be centered with the renal arteries to enable placement of the extensions. The aperture opening and side branch extensions contain hook and loop structures to provide a variably positionable seal of the aperture opening.
    Type: Grant
    Filed: September 2, 2005
    Date of Patent: December 16, 2014
    Assignee: Medtronic Vascular, Inc.
    Inventors: Curtis Hanson, Scott Cook, Joseph Lessar
  • Patent number: 8906084
    Abstract: Embodiments provide methods and systems for treating aneurysms using filling structures filled with a curable medium. An embodiment of a method comprises positioning at least one double-walled filling structure across the aneurysm and filling the structure(s) with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device while and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint. The medium is hardened while the lumen remains supported by the balloon. The balloon is then removed after the medium hardens.
    Type: Grant
    Filed: January 7, 2010
    Date of Patent: December 9, 2014
    Assignee: Nellix, Inc.
    Inventors: Michael A. Evans, Gwendolyn A. Watanabe, Amy Lee, Steven L. Herbowy
  • Patent number: 8859934
    Abstract: A method of removing slag formed during laser cutting a hypotube may include flowing cooling gas into a laser nozzle, directing flow of the cooling gas onto an external surface of the hypotube, and injecting cooling fluid into an inner lumen of the hypotube at a velocity. Flowing the cooling gas and injecting the cooling fluid may at least partially remove slag from the external surface of the hypotube.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: October 14, 2014
    Assignee: Insera Therapeutics, Inc.
    Inventors: Vallabh Janardhan, Vikram Janardhan
  • Publication number: 20140277385
    Abstract: A method for forming a material in an in situ medical device by initiating polymerization of water soluble polymer precursors in an aqueous solution during or after transport of the polymerizable solution from its storage container to a space inside the in situ medical device is described. The stored aqueous solution with water soluble precursors lacks a free radical initiator which, in a powder form, is introduced into the aqueous solution during or after its transport into the space inside the in situ medical device. This storage and delivery system provides greater stability to the stored aqueous solution, allowing it to be stored at ambient temperature and providing extended shelf life over the solutions used in existing in situ polymerization systems. The flexibility to store and deliver/transport only one aqueous solution, instead of requiring the use of two different solutions, is also a benefit.
    Type: Application
    Filed: March 7, 2014
    Publication date: September 18, 2014
    Applicant: Endologix, Inc.
    Inventors: Charles Bankert, Paolo Mendoza, Stefan Schreck
  • Patent number: 8814928
    Abstract: An apparatus for repairing an aneurysm comprises a device having an inner graft tube and an inflatable outer balloon attached to an outer surface of the inner graft tube, and an inflatable deployment balloon. The inner graft tube is expandable within an artery to form a seal with the arterial wall above and/or below an aneurysm. The outer balloon is inflatable within the aneurysm with a rapidly settable substance to fill the aneurysm and support the device. The deployment balloon has an uninflated condition to fit within the inner graft tube and is inflatable within the inner graft tube to expand the inner graft tube within the artery and to maintain the inner graft tube expanded within the artery during inflation of the outer balloon.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: August 26, 2014
    Assignee: Vortex Innovation Limited
    Inventor: Marie Therese Robin
  • Patent number: 8747345
    Abstract: A bypass provided by a bypass conduit disposed in a vessel which is collateral to an occluded vessel. The bypass conduit comprises a helical wire body having a plurality of connectors connecting adjacent turns of the helical body.
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: June 10, 2014
    Assignee: Vanderbilt University
    Inventor: Joseph G Salloum
  • Patent number: 8641746
    Abstract: Apparatus and methods for delivering stents and other prostheses to body lumens include a prosthesis forming and deploying mechanism carried at the distal end of a catheter shaft. The mechanism is adapted to form and deploy prostheses of a variable length, and to form and deploy multiple prostheses during a single interventional procedure.
    Type: Grant
    Filed: May 31, 2005
    Date of Patent: February 4, 2014
    Assignee: J.W. Medical Systems Ltd.
    Inventors: Bernard Andreas, Craig Welk, David Sanderson
  • Publication number: 20130211500
    Abstract: Disclosed are liquid cast biodegradable arterial stents and methods for preparing liquid cast biodegradable arterial stents. The typically includes a biodegradable polymer and may include an agent for treating neointimal hyperplasia.
    Type: Application
    Filed: April 14, 2011
    Publication date: August 15, 2013
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Melina R. Kibbe, Guillermo A. Ameer
  • Publication number: 20130204351
    Abstract: The present invention provides methods and apparatus for the endoluminal positioning of an intraluminal prosthesis at a target location within a body lumen. The device may comprise a porous, multi-layer prosthesis that can include several different tubular mesh components such as an everted tubular component, an tubular component that expands to various different sizes, a bifurcated tubular component, and a tubular component with an undulating expanded shape, among others. Various components can have different densities or pore sizes and can be overlaid on each other to selectively block different regions of a vessel.
    Type: Application
    Filed: February 4, 2013
    Publication date: August 8, 2013
    Applicant: Inceptus Medical LLC
    Inventor: Inceptus Medical LLC
  • Patent number: 8479742
    Abstract: Medical devices and related methods are disclosed for delivering an implant into the body of a patient. The devices include a damping assembly having an internal chamber with a varying inner diameter, and a piston slideably disposed therein. The piston is operably connected with a catheter portion such that movement of the piston is associated with concurrent movement of the catheter for implant delivery. The varying inner diameter of the damping assembly results in a decrease in damping force during implant delivery, thus providing a substantially constant velocity of implant delivery.
    Type: Grant
    Filed: February 28, 2011
    Date of Patent: July 9, 2013
    Assignee: Hologic, Inc.
    Inventor: Matthew LaPlaca
  • Patent number: 8465436
    Abstract: An implant centering system includes a sensor connected to a hollow cylindrical anchor via at least two struts. The hollow cylindrical anchor is transformable between a radially compressed configuration for delivery and a radially expanded configuration for lodging against a vessel wall. The struts longitudinally relocate the sensor between a first position in which the sensor is longitudinally spaced apart from the radially compressed anchor, and a second position in which the sensor is at least partially within a lumen of the radially expanded anchor and radially centered within vessel. In one embodiment, the struts are heat-set into a curved configuration and an externally applied force longitudinally relocates the sensor until the struts lock over center into their heat-set configuration. In another embodiment, radial expansion of the anchor longitudinally relocates the sensor without an externally applied force.
    Type: Grant
    Filed: April 27, 2010
    Date of Patent: June 18, 2013
    Assignee: Medtronic Vascular, Inc.
    Inventor: Erik Griswold
  • Patent number: 8460357
    Abstract: Apparatus and methods for delivering stents and other prostheses to body lumens include a prosthesis forming and deploying mechanism carried at the distal end of a catheter shaft. The mechanism is adapted to form and deploy prostheses of a variable length, and to form and deploy multiple prostheses during a single interventional procedure.
    Type: Grant
    Filed: May 31, 2005
    Date of Patent: June 11, 2013
    Assignee: J.W. Medical Systems Ltd.
    Inventors: Michael C. McGarry, Craig Welk
  • Patent number: 8366764
    Abstract: By a contrast means contained in an inventive stent which has a greater permeability for x-radiation features than the body tissue surrounding the stent in a relevant body conduit, this stent can be clearly detected in its position on an x-ray image of the relevant body conduit while at the same time exhibiting good biological compatibility; a gas, especially one contained in cavities of the stent is provided as a contrast means. The inventive production method for this stent with the aid of a catheter embodied specially for the purpose enables the production of the stent from a malleable polymer mass in the relevant body conduit so that the stent is adapted especially precisely to the shape of the relevant body conduit.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: February 5, 2013
    Assignee: Siemens Aktiengesellschaft
    Inventor: Mathias Hörnig
  • Patent number: 8292947
    Abstract: In order to create a stent, which despite being simple to guide in the relevant body conduit allows flexible adaptability to the body conduit in a simple manner while avoiding undesirably high expansion forces on the wall of the body conduit, in accordance with the invention a catheter is provided, with an essentially tubular filling area surrounding the part of the catheter which can be introduced into the body conduit, which can be filled with a plastic mass which forms the stent by a process of hardening; there is provision for positioning the filling area at the position intended for the stent in the body conduit, for hardening the plastic mass in the filling area, for creating the stent and for removing the catheter from the body conduit with the stent remaining in the body conduit.
    Type: Grant
    Filed: May 25, 2006
    Date of Patent: October 23, 2012
    Assignee: Siemens Aktiengesellschaft
    Inventor: Mathias Hörnig
  • Publication number: 20120265287
    Abstract: Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms are disclosed. The systems include an insertable medical device and an in-situ forming foam that is formed from a polymer that reacts in an aqueous environment. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.
    Type: Application
    Filed: June 25, 2012
    Publication date: October 18, 2012
    Applicant: Arsenal Medical, Inc.
    Inventors: Upma Sharma, Gregory Zugates, Rany Busold, Toby Freyman
  • Publication number: 20120245674
    Abstract: A vascular remodeling device is provided. The device includes an anchor portion, sized for deployment in a blood vessel, that is radially expandable from a collapsed state to an expanded state. The device also includes a distal portion that is sized for deployment in a blood vessel. The distal portion is radially expandable from a collapsed state to an expanded state and, in some embodiments, has a distal face that is sufficiently occlusive in the distal-to-proximal direction to perform a therapeutic blocking function at an aneurysm. Some embodiments have an intermediate portion that connects a distal end of the anchor portion and a proximal end of the distal portion, and in some embodiments, the anchor portion and distal portion are able to pivot relative to each other at or near the intermediate portion.
    Type: Application
    Filed: March 23, 2012
    Publication date: September 27, 2012
    Applicant: TYCO HEALTHCARE GROUP LP
    Inventors: Masoud Molaei, Evan David Epstein, Gabriel Francis Wilgus Newell, Quang Tran
  • Patent number: 8206433
    Abstract: A stent is described that is capable of expanding and thereafter recoiling to its initial coiled state within a biliary duct. A delivery system is utilized to deploy the stent in its natural coiled state into a targeted site of an occluded biliary duct. A balloon from the delivery system is positioned within a lumen defined by the inner coiled arm of the stent. The inflation of a balloon from the delivery system causes the inner coiled arm to radially move outward and engage the outer coiled arm to form an expanded stent. The expanded stent can revert back to its recoiled state by deploying a balloon through a lumen of the expanded stent. Inflation of the balloon disengages the inner coiled arm from the outer coiled arm thereby collapsing the inner coiled arm radially outward and onto the outer coiled arm to form a recoiled stent. The recoiled stent can be removed from the biliary duct.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: June 26, 2012
    Assignee: Cook Medical Technologies LLC
    Inventor: Brian K. Rucker
  • Patent number: 8044137
    Abstract: Certain embodiments of the invention include forming a material in situ by introducing into a space within a patient a water soluble polymer precursor of at least about 10,000 molecular weight solubilized in a flowable aqueous solution. Functional groups on the polymer precursor undergo covalent bonding in situ to form a solid and nonbiodegradable material having a swellability less than about 20% v/v and a Young's modulus of at least about 100 kPa within about 30 seconds to about 30 minutes of initiating a chemical reaction of the functional groups to form the solid material.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: October 25, 2011
    Assignee: Incept LLC
    Inventors: Farhad Khosravi, James Dreher
  • Patent number: 8029556
    Abstract: The present disclosure concerns embodiments of a reshaping apparatus and methods for restoring the conical shape of a dilated heart ventricle, or at least reshaping the ventricle to a more conical shape to counter the effects of dilation, thereby improving pumping efficiency. In an exemplary embodiment, a reshaping apparatus comprises an implantable body that can be delivered to a dilated left ventricle via the patient's vasculature in a minimally-invasive procedure. When deployed inside the left ventricle, the body is adapted to apply a longitudinal (downward) force against the inner surface of the left ventricle that causes the ventricle to distend or elongate downwardly relative to the base of the heart so as to at least partially restore the conical shape of the heart. In other embodiments, one or more tension members can be secured to heart tissue inside a heart chamber or on the outside of the heart and placed in tension to reshape the geometry of the heart.
    Type: Grant
    Filed: April 2, 2007
    Date of Patent: October 4, 2011
    Assignee: Edwards Lifesciences Corporation
    Inventor: Stanton J. Rowe
  • Patent number: 7872068
    Abstract: Certain embodiments of the invention include forming a material in situ by introducing into a space within a patient a water soluble polymer precursor of at least about 10,000 molecular weight solubilized in a flowable aqueous solution. Functional groups on the polymer precursor undergo covalent bonding in situ to form a solid and nonbiodegradable material having a swellability less than about 20% v/v and a Young's modulus of at least about 100 kPa within about 30 seconds to about 30 minutes of initiating a chemical reaction of the functional groups to form the solid material.
    Type: Grant
    Filed: May 30, 2006
    Date of Patent: January 18, 2011
    Assignee: Incept LLC
    Inventors: Farhad Khosravi, James Dreher
  • Publication number: 20100331947
    Abstract: A medical device comprising a compartment capable of receiving and holding a substance in a liquid form is disclosed. The compartment is inflatable from a deflated state to an inflated state, such that when the compartment is in the deflated state, the outer wall of the membrane is substantially impermeable to the substance, and when the compartment is in the inflated state, the substance is allowed to permeate through the outer wall.
    Type: Application
    Filed: February 16, 2006
    Publication date: December 30, 2010
    Inventors: Alon Shalev, Alexander Dubson
  • Patent number: 7857748
    Abstract: Methods of manufacture of endoprostheses comprising one or more photocurable materials are disclosed. The endoprostheses may comprise regions wherein the photocurable materials are selectively disposed about the endoprosthesis and are cured according to desired parameters to achieve varying desired properties. Photolithographic masking material may be selectively disposed about an inflatable balloon and exposed to a radiation emitting catheter.
    Type: Grant
    Filed: October 19, 2006
    Date of Patent: December 28, 2010
    Assignee: Syne Cor, LLC
    Inventors: Michael S. Williams, Kevin D. Holbrook, Richard A. Glenn, Jeffrey A. Smith, Joseph M. DeSimone
  • Patent number: 7857766
    Abstract: A system and method that minimizes plaque accumulation on a stent and thereby restenosis that could require a subsequent invasive medical procedure following implantation of the stent in a patient. A plurality of electrically-powered, biocompatible devices, implantable via injection, are positioned within the patient proximate to the stent and under control of a externally-placed controller are commanded to emit ultrasonic waves corresponding to the mechanical resonance of the stent. By controlling the frequency and the relative phases of the ultrasonic waves, the accumulation of plaque on the stent can thus be minimized.
    Type: Grant
    Filed: June 20, 2005
    Date of Patent: December 28, 2010
    Assignee: Alfred E. Mann Foundation for Scientific Research
    Inventors: Brian J. Lasater, Lee J. Mandell
  • Patent number: 7803178
    Abstract: The present invention provides inflatable porous implants, such as grafts, stent-grafts, and bladders, as well as methods and kits for drug delivery. In particular, the grafts and stent-grafts of the present invention provide for the delivery of a therapeutic agent into a flow conduit in the body. The inflatable porous implants provide for direct delivery of larger, more precise dosages of drugs over longer administration periods into the body. Moreover, these inflatable porous implants are often flexible when inserted and have a low profile delivery configuration for easy placement. The implants of the present invention further provide a mechanical or structural function in addition to drug delivery in a single integrated structure.
    Type: Grant
    Filed: January 30, 2004
    Date of Patent: September 28, 2010
    Assignee: TriVascular, Inc.
    Inventors: Robert G. Whirley, James M. Shapiro
  • Patent number: 7749265
    Abstract: A radio frequency antenna is provided for use with a medical device for implantation into an animal. The antenna comprises a coil formed by a wire that includes a core formed of a shape-memory material with an electrically conductive first layer applied to an outer surface of the core. A second layer, of an electrically insulating and biologically compatible material, extends around the first layer. If necessary to reduce friction a lubricant is place between the first and second layers. If second layer is formed of porous material or a non-biological compatible material, a biological compatible outer layer surrounds the second layer thereby providing a barrier that is impermeable to body fluids of the animal.
    Type: Grant
    Filed: October 5, 2005
    Date of Patent: July 6, 2010
    Assignee: Kenergy, Inc.
    Inventors: Stephen Denker, Cherik Bulkes, Arthur J. Beutler
  • Patent number: 7704276
    Abstract: A woven tubular endoprosthesis comprising means for locking the endoprosthesis in a deployed configuration is disclosed. The means for locking the endoprosthesis may comprise locking protrusions, notches, a chemical bond, a curable bond, or other mechanism. The woven fibers comprising the endoprosthesis may be hollow and comprise circumferentially oriented polymeric chains, and may be filled with a curable material. A method of treatment using an endoprosthesis according to the invention is also disclosed.
    Type: Grant
    Filed: September 30, 2006
    Date of Patent: April 27, 2010
    Assignee: SyneCor, LLC
    Inventors: Michael S. Williams, Richard A. Glenn, Jeffrey A. Smith, Kevin D. Holbrook, Joseph M. DeSimone
  • Patent number: 7682383
    Abstract: A device for repairing an aneurysm by deployment within the aneurysm comprises a graft tube, at least part thereof having an inflatable wall whereby the tube can be deployed in an artery and inflated to grip at least part of the arterial wall.
    Type: Grant
    Filed: June 17, 2002
    Date of Patent: March 23, 2010
    Inventor: Marie Therese Robin
  • Patent number: 7615046
    Abstract: A urological medical system for performing a controlled hydrodistention of the urinary bladder for treating a bladder dysfunction problem comprised of a programmed CPU with associated computer equipment for facilitating an automatic control of a treatment procedure to be performed on a patient, a saline solution warmer, a saline solution pump, a four-way catheter wherein a channel is provided for monitoring the pressure within the bladder during the procedure, a syringe for infusing a medicine through the catheter and a strapping device to secure the syringe and to slidingly engage the catheter to a leg of the patient. Desired parameters are monitored during the procedure and a desired pressure is maintained in the bladder for a predetermined time to perform the controlled hydrodistention of the urinary bladder.
    Type: Grant
    Filed: October 25, 2006
    Date of Patent: November 10, 2009
    Inventor: Sobhy Shehata
  • Patent number: 7611887
    Abstract: The invention concerns a micro-muscle designed to be immersed in a biological liquid, comprising a deformable chamber whereof one portion at least consists of a semipermeable membrane, said chamber containing a solution capable of osmotic activity. The solution is preferably activated by a product to be injected into the biological liquid.
    Type: Grant
    Filed: July 17, 2002
    Date of Patent: November 3, 2009
    Assignee: Universite Joseph Fourier
    Inventors: Philippe Cinquin, Olivier Cinquin, Denis Favier, Laurent Orgeas, Matthieu Pecher, Sonia Pujol
  • Patent number: 7530988
    Abstract: Aneurysms are treated by filling a double-walled filling structure with a curable medium. The structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. The filling structures are preferably used in pairs for providing flow into the iliac arteries when treating abdominal aortic aneurysm.
    Type: Grant
    Filed: July 22, 2005
    Date of Patent: May 12, 2009
    Assignee: Nellix, Inc.
    Inventors: Michael A. Evans, Thomas Howell, Gwendolyn A. Watanabe, Bhupendra Shah, James McKinley
  • Publication number: 20080312733
    Abstract: An implantable, radially distensible stent includes a plurality of helically wound elongate members. The members include an overlapping portion having a longitudinal extent, opposed and convexly rounded sides defining a width of the members and opposed luminal and exterior surfaces. The members include shape memory polymer. The side of one elongate member slidingly overlaps the side of an adjacent elongate member to form a self-supporting wall structure of a stent. The stent wall is self-supporting without other support structure incorporated into or abutting the elongate members. Further, the shape memory polymer may comprise a biodegradable or bioabsorbable elements.
    Type: Application
    Filed: June 10, 2008
    Publication date: December 18, 2008
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventor: Gary Jordan
  • Publication number: 20080294237
    Abstract: Methods and systems for preventing aneurysm rupture and reducing the risk of migration and endoleak are disclosed. Specifically, an inflatable liner is applied directly to treat the interior of the aneurysm site. Also disclosed are methods to deliver the inflatable liner directly to treatment sites.
    Type: Application
    Filed: February 26, 2008
    Publication date: November 27, 2008
    Inventor: Jack Fa-De Chu
  • Publication number: 20080146489
    Abstract: The present invention relates to the regional delivery of therapeutic agents for the treatment of vascular diseases wherein regional delivery refers to delivery of a therapeutically effective amount of the therapeutic agent to an area of the vessel that includes not only afflicted tissue but non-afflicted tissue at the periphery of the afflicted tissue as well.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 19, 2008
    Inventors: Stephen D. Pacetti, Paul M. Consigny, Ronald W. Heil, Florian Niklas Ludwig, Dariush Davalian, Li Zhao, Irina Astafieva, Jinping Wan, Fozan El-Nounou, Katsuyuki Murase, Syed F.A. Hossainy, Rachel Bright, Jeffrey Ellis
  • Publication number: 20070282366
    Abstract: Certain embodiments of the invention include forming a material in situ by introducing into a space within a patient a water soluble polymer precursor of at least about 10,000 molecular weight solubilized in a flowable aqueous solution. Functional groups on the polymer precursor undergo covalent bonding in situ to form a solid and nonbiodegradable material having a swellability less than about 20% v/v and a Young's modulus of at least about 100 kPa within about 30 seconds to about 30 minutes of initiating a chemical reaction of the functional groups to form the solid material.
    Type: Application
    Filed: May 30, 2006
    Publication date: December 6, 2007
    Inventors: Farhad Khosravi, James Dreher
  • Patent number: 7198637
    Abstract: The invention provides a method of manufacturing a system for treating a vascular condition. A catheter including an inflatable balloon is provided. A stent is positioned over the balloon. An adhesive material is applied between an inner surface of the stent and an outer surface of the balloon. The adhesive material is heated to above a melting point of the adhesive material. The adhesive material is cooled to below a melting point of the adhesive material to provide an adhesive bond that retains the stent to the catheter during vascular delivery, wherein the stent is released from the balloon following inflation and deflation of the balloon at a treatment site.
    Type: Grant
    Filed: April 21, 2003
    Date of Patent: April 3, 2007
    Assignee: Medtronic Vascular, Inc.
    Inventors: Susheel R. Deshmukh, Kaushik A. Patel, Ronan Rogers
  • Patent number: 7141061
    Abstract: Novel endoprostheses comprising one or more photocurable materials are disclosed. Said endoprostheses may comprise regions wherein said photocurable materials are selectively disposed about said endoprosthesis and are cured according to desired parameters to achieve varying desired properties. Said properties may include but are not limited to cross-linking density, material density, modulus of elasticity, rate of erosion, extensibility, compressibility, mechanical strength, tensile strength, crystallinity, diffusion coefficient, and permeability.
    Type: Grant
    Filed: January 15, 2003
    Date of Patent: November 28, 2006
    Assignee: SyneCor, LLC
    Inventors: Michael S. Williams, Kevin D. Holbrook, Richard A. Glenn, Jeffrey A. Smith, Joseph M. DeSimone
  • Patent number: 7108715
    Abstract: A graft (1) which is in the form of an inflatable member adapted to be formed into a predetermined and/or selected shape when deployed in situ by filling with a filler material (6) which can be made rigid in situ and deployed on a balloon catheter (12). The deployment balloon (13) is formed from a non-compliant material.
    Type: Grant
    Filed: October 24, 2002
    Date of Patent: September 19, 2006
    Assignees: Cook Incorporated, William A. Cook Australia Pty Ltd.
    Inventors: Michael Lawrence-Brown, Kurt Liffman, David Ernest Hartley
  • Patent number: 7008446
    Abstract: A prosthesis for insertion into a body passage is disclosed. The prosthesis includes a plastic or polymer base material which is compatible with living tissue and which possesses a memory of a predetermined configuration. The base material further has a glass transition temperature at which the prosthesis can be molded intravascularly from the predetermined configuration to a larger-radius implant configuration, which is sized and shaped to conform to an internal anatomy of the body passage to expand a narrow segment of or to occlude an opening of an out pouch of the body passage. The glass transition temperature is greater than a temperature of the body passage so that the prosthesis after being molded can be allowed to cool to the temperature of the body passage.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: March 7, 2006
    Inventors: James Peter Amis, Hoi Sang U
  • Patent number: 6958073
    Abstract: The invention provides a method of manufacturing a system for treating a vascular condition. A catheter including an inflatable balloon is provided. A stent is positioned over the balloon. An adhesive material is applied between an inner surface of the stent and an outer surface of the balloon. The adhesive material is heated to above a melting point of the adhesive material. The adhesive material is cooled to below a melting point of the adhesive material to provide an adhesive bond that retains the stent to the catheter during vascular delivery, wherein the stent is released from the balloon following inflation and deflation of the balloon at a treatment site.
    Type: Grant
    Filed: April 13, 2004
    Date of Patent: October 25, 2005
    Assignee: Medtronic Vascular, Inc.
    Inventors: Ronan Rogers, Susheel R. Deshmukh, Kaushik A. Patel
  • Publication number: 20040236410
    Abstract: A system for forming a polymeric body includes a non-perforated irrigating shaped form, such as a catheter balloon, fluidly coupled with a container storing a first component. The irrigating shaped form is sized and dimensioned for positioning within a patient's body. A second component is disposed at the irrigating shaped form. The second component can either be supplied separately to the irrigating shaped form, pre-exist within the irrigating shaped form, exist as a coating or other residual element on the irrigating shaped form, or the like. In a corresponding method, a first component reacts with the second component upon delivery of the first component from the first component container through the irrigating shaped form. The reaction of the components forms a compound emitted from the irrigating shaped form to a targeted location within the patient's body. The compound cures to form the polymeric body.
    Type: Application
    Filed: May 22, 2003
    Publication date: November 25, 2004
    Applicant: ATRIUM MEDICAL CORP.
    Inventors: Steve A. Herweck, Paul Martakos
  • Publication number: 20040230316
    Abstract: Methods of treating the prostate include administering a thermal ablation therapy and inhibiting the obstruction or closure of the prostatic urethral opening by forming a biodegradable stent in situ in the subject such that the stent attaches to the walls of the prostatic urethra. A related method of treating BPH includes thermally treating or ablating localized tissue in the prostate with a treatment catheter and inserting flowable stent material via the treatment catheter into the prostate (either before, during, or after the thermal treatment), forming the flowable stent material so that it defines a stent that remains in position after removal of the treatment catheter to inhibit the closure of the urinary passage. Associated stents and catheters are included.
    Type: Application
    Filed: May 12, 2003
    Publication date: November 18, 2004
    Inventors: Iulian Cioanta, Richard Barry Klein
  • Publication number: 20040215321
    Abstract: Percutaneous treatment of aortic aneurysms and like vascular anomalies by an apparatus and method wherein the apparatus is delivered via catheter and comprises a sleeve with at least one peripheral conduit which is caused to assume an expanded, rigid configuration by the introduction of a chemical or mechanical hardening means, whereby the sleeve is caused to assume an open cylindrical configuration for fluid flow therethrough.
    Type: Application
    Filed: May 11, 2004
    Publication date: October 28, 2004
    Inventors: Thomas J. Holman, Darlene A. Thometz, Fertac Bilge, Paul J. Buscemi, David H. Donabedian
  • Publication number: 20040215331
    Abstract: Blood vessels and other body lumens are stented using multiple, discreet stent structures, or continuous coiled or mesh stent structures. Stent structures may be balloon expandable or self-expanding and are delivered by a delivery catheter which is repositioned to spaced-apart delivery sights. By coating the stents with particular biologically active substances, hyperplasia within and between the implanted stents can be inhibited. An exemplary delivery catheter comprises a catheter body having a deployment mechanism for deploying one or more stents of selectable length into the vessel.
    Type: Application
    Filed: July 21, 2003
    Publication date: October 28, 2004
    Applicant: XTENT, INC.
    Inventors: Sunmi Chew, Bernard Andreas, Hanson S. Gifford, Ron French, Mark E. Deem, Allan Will