Stent Structure Patents (Class 623/1.15)
  • Patent number: 11185405
    Abstract: The present invention relates to a radially collapsible frame (1) for a prosthetic valve, the frame (1) comprising an outflow end region (3) at a proximal end of the frame (1) and an inflow end region (2) at a distal end of the frame (1), opposite to the outflow end region (3). The frame (1) further includes at least two radially spaced commissure attachment regions (10, 10?, 10?) and a cell structure (30), composed of a plurality of lattice cells being arranged radially around a flow axis of the frame (1) and connecting the at least two commissure attachment regions (10, 10?, 10?). Finally, at least one anchoring/positioning arch (20, 20?, 20?) is provided, wherein said at least one anchoring/positioning arch (20, 20?, 20?) radially overlaps the cell structure (30) at least partially.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: November 30, 2021
    Assignee: JenaValve Technology, Inc.
    Inventors: Michael J. Girard, Martin Schlun
  • Patent number: 11169142
    Abstract: In some embodiments, the invention provides a method for identifying a patient suffering from or suspected of suffering in from a disease associated with the cardiovascular system that is having a subnormal response to the treatment for the disease comprising: subjecting a blood sample from a patient being treated for a disease to a viscoelastic analysis in the presence of a known amount of a thrombolytic agent, to obtain a coagulation characteristic value of the patient; and comparing the coagulation characteristic value of the patient to a coagulation characteristic value of a healthy individual, wherein a difference in the coagulation characteristic value of the patient as compared to the coagulation characteristic value of the healthy individual identifies the patient as a patient having a subnormal response to treatment.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: November 9, 2021
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventor: Michael P. Chapman
  • Patent number: 11160654
    Abstract: Apparatus and method are described including identifying a subject as suffering from a condition that causes the subject to have elevated central venous pressure. In response thereto, a device is placed inside the subject's vena cava such that an upstream end of the device is placed at a location upstream of junctions of the vena cava with all of the subject's renal veins. The device defines a passage through the device, at least a portion of the passage converging in a direction from an upstream end of the device to downstream end of the device. Other applications are also described.
    Type: Grant
    Filed: February 12, 2019
    Date of Patent: November 2, 2021
    Assignee: MAGENTA MEDICAL LTD.
    Inventor: Yosi Tuval
  • Patent number: 11160506
    Abstract: This invention relates to an implantable device for a physiologic sensor, comprising an implantable expandable anchor, a bridge on which the sensor is secured, as well as an optional adapting ring. The invention also relates to a method of monitoring bodily functions using the anchor and sensor. The anchor is compressed and the bridge assumes an elongated shape during delivery to a target lumen. Upon deployment at the target site, the anchor expands and the bridge bows into the interior lumen of the expanded anchor, distancing the sensor from the vessel wall. This invention also relates to a method of manufacturing said device and a method of implanting a sensor.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: November 2, 2021
    Assignee: Microtech Medical Technologies Ltd
    Inventors: Yekaterina Dlugach, Nadav Agian
  • Patent number: 11154287
    Abstract: A stent retractor has a radially flexibly expandable tubular sheath divided in the peripheral direction into at least two sections, specifically a reinforcing section and an expanding section, with radial flexibilities that differ from one another, these sections being interconnected integrally. The stent retractor includes axial segments that are connected by a puzzle-type connection allowing simple separation or length adjustment in the axial direction (including when in situ) while also being made integrally, for example by a laser or water jet cutting method, preferably from a tubular blank.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: October 26, 2021
    Assignee: AESCULAP AG
    Inventors: Jens Beger, Susanne Klingseis, Christian Grimm, Mario Serpa
  • Patent number: 11152087
    Abstract: A method, system and computer program product for ensuring quality in electronic health data. Data processing pipelines among different tenants are monitored for data artifacts generated from electronic health data, where a “data artifact” refers to the tangible by-products produced during the processing of the electronic health record datasets generated by the electronic health record systems as well as the datasets themselves. Out of the generated data artifacts, those data artifacts that are produced from the same stage of the data processing pipelines among the different tenants are aggregated. A set of metrics at various levels of a dataset hierarchy are produced from the aggregated data artifacts. Such metrics provide information about a quality of the electronic health data. A quality report, which may include flagged issues with the datasets, is then generated and presented to a user based on an analysis of the produced set of metrics.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: October 19, 2021
    Assignee: International Business Machines Corporation
    Inventors: Matthew Hagenbuch, Yifan Xu, James Natale, Matthew M. Pohlman
  • Patent number: 11147696
    Abstract: A multilayer bioresorbable stent having sustained drug delivery is disclosed herein. The bioresorbable stent releases a therapeutic substance from the body of the bioresorbable stent starting when the bioresorbable stent is implanted within an anatomical lumen and ending when the entire mass of the bioresorbable stent is no longer present within the anatomical lumen. The bioresorbable stent releases the therapeutic substance gradually during the treatment as the mass of the each layer of the bioresorbable stent erodes. Methods of making the therapeutic layers within the bioresorbable sent are further disclosed. Sustained drug delivery reduces the risk of late and very late stent thrombosis.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: October 19, 2021
    Inventors: John James Scanlon, Catherine Ann Scanlon
  • Patent number: 11135074
    Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: October 5, 2021
    Assignee: ABBOTT CARDIOVASCULAR SYSTEMS INC.
    Inventors: Syed Hossainy, Chad J. Abunassar, Michael Huy Ngo, Erik David Eli, Santosh V. Prabhu, Mikael Trollsas, Richard Rapoza
  • Patent number: 11123461
    Abstract: A method and device for localized treatment of tissues or organs that were exposed to ischemia and reperfusion (IR) injury, in order to reduce their structural damage and loss of function. The method further includes intra-arterial treatment of transplanted tissues or organs, which are exposed to similar damage of IR and are at risk of impaired function. Leptin antagonist is administered as a bolus injection directly into a re-opened artery, which supplies blood to the tissue or organ involved, immediately after reperfusion. In some cases, after administering a bolus injection of leptin antagonist, the effect of leptin antagonist in the involved organ can be prolonged by deploying a double function drug eluting stent, which elutes leptin antagonist into the lumen, e.g., by sustained release, while eluting antiproliferative drug into the vessel wall to prevent local stenosis, which may appear due to stent deployment.
    Type: Grant
    Filed: October 8, 2018
    Date of Patent: September 21, 2021
    Assignee: REMODELESS CV LTD
    Inventor: Jacob Schneiderman
  • Patent number: 11116877
    Abstract: Aspects include methods of fabricating antibacterial surfaces for medical implant devices including patterning a photoresist layer on a silicon substrate and etching the silicon to generate a plurality of nanopillars. Aspects also include removing the photoresist layer from the structure and coating the plurality of nanopillars with a biocompatible film. Aspects also include a system for preventing bacterial infection associated with medical implants including a thin silicon film including a plurality of nanopillars.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: September 14, 2021
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stacey M. Gifford, Huan Hu, Emily R. Kinser, Roy R. Yu, Sufi Zafar
  • Patent number: 11103371
    Abstract: An implantable prosthesis designed to transition from a contracted state to an expanded state, including a continuous tubular helical winding and a plurality of bridges. The helical winding includes a plurality of circumferential sections spaced apart along a helical axis, each of the plurality of circumferential sections forming a non-orthogonal helical angle relative to the helical axis. The plurality of bridges connect adjacent circumferential sections, each having a length extending from a first end to a second end on a plane orthogonal to the helical axis, the length being equal to a circumferential offset between the adjacent circumferential sections in both the contracted state and the expanded state. The implantable prosthesis also includes a first annular ring orthogonal to the helical axis, and a first marker having a first end connected to the first annular ring, and a second end coupled to the first end of the helical winding.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: August 31, 2021
    Assignee: Angiomed GmbH & Co. Medizintechnik KG
    Inventors: Thomas O. Bales, Jr., Scott L. Jahrmarkt, Charles R. Slater, Peter K. Kratsch
  • Patent number: 11103832
    Abstract: According to one embodiment, a composition of matter includes: a first system of continuous voids arranged in a three-dimensional matrix; a second system of continuous voids arranged in the three-dimensional matrix; and a nanoporous barrier separating the first system of continuous voids and the second system of continuous voids. The first system of continuous voids and the second system of continuous voids are interwoven but independent so as to form a plurality of channels through the three-dimensional matrix. Corresponding methods for forming the composition of matter are also disclosed.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: August 31, 2021
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Jianchao Ye, Andreas C. Baumgaertel, Juergen Biener, Monika M. Biener, Sangil Kim
  • Patent number: 11103252
    Abstract: The device includes a braided component formed from a network of wires having at least two different diameters. The outer surface of the braided component has roughness from about 30 microns to about 90 microns and the wires of different diameters provide the desired porosity to the device. The network of wires includes a biocompatible shape memory alloy and a noble metal as a coating material.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: August 31, 2021
    Inventor: Swaminathan Jayaraman
  • Patent number: 11083576
    Abstract: A method of implanting a replacement mitral valve can include expanding a replacement mitral valve to a first expanded configuration. The replacement mitral valve can include a force-expanding mitral valve lattice and a self-expanding valve trampoline lattice. The mitral valve lattice has an inflow end portion and an outflow end portion, and the valve trampoline lattice is attached to the outflow end portion of the mitral valve lattice. The method can also include rotating a plurality of jack screws connected to the mitral valve lattice. The jack screws can be configured to expand the mitral valve lattice from the first expanded configuration to a second expanded configuration.
    Type: Grant
    Filed: February 14, 2019
    Date of Patent: August 10, 2021
    Assignee: Edwards Lifesciences CardiAQ LLC
    Inventors: Richard George Cartledge, Derek Dee Deville, Kevin W. Smith, James L. Greene, Jorge H. Jimenez
  • Patent number: 11083473
    Abstract: Intraluminal devices and methods for removing an obstruction from a blood vessel using an intraluminal device are provided. The intraluminal device can include a flexible shaft and an expandable wire mesh structure extending from the flexible shaft, the wire mesh structure including at least one first expandable section having a first wire arrangement pattern and at least one second expandable section having a second wire arrangement pattern different from the first wire arrangement pattern. In addition, interstices in the at least one first expandable section can differ in size from interstices in the at least one second expandable section.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: August 10, 2021
    Assignee: Rapid Medical Ltd.
    Inventors: Yuri Sudin, Aharon Friedman, Ronen Eckhouse
  • Patent number: 11058564
    Abstract: A stent for vascular interventions having a hybrid open cell geometry. Variants of the stent include bare metal stents and drug-eluting stents. Embodiments of the stent include end projections for radiopaque markers or a discontinuous partial radiopaque coating on low-stress or low-strain regions of the peripheral stent. The stents of the invention are characterized by having thin walls, nested rows of struts, high expansion ratio, high and uniform radial force over entire diametric size and length of device, crush resistance up to and including about 90% of its fully expanded diameter, high fatigue resistance and high corrosion resistance.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: July 13, 2021
    Assignee: Vactronix Scientific LLC
    Inventors: Scott P. Carpenter, Christian G. Palmaz
  • Patent number: 11051958
    Abstract: A biodegradable in vivo supporting device is disclosed. In one embodiment, a coated stent device includes a biodegradable metal alloy scaffold made from a magnesium alloy, iron alloy, zinc alloy, or combination thereof, and the metal scaffold comprises a plurality of metal struts. The metal struts are at least partially covered with a biodegradable polymer coating. A method for making and a method for using a biodegradable in vivo supporting device are also disclosed.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: July 6, 2021
    Assignee: Q3 MEDICAL DEVICES LIMITED
    Inventor: Eric K. Mangiardi
  • Patent number: 11045313
    Abstract: A prosthesis for placement within a native mitral valve includes an expandable frame having locking tabs disposed along a proximal end. A plurality of distal anchors are disposed along a distal end of the frame. Each distal anchor is provided with a cushion cover. An outer fabric member surrounds the frame and may extend outwardly from the frame in an expanded condition for providing an improved seal in the region of a mitral annulus. A valve body is positioned within an interior of the expandable from for allowing blood flow in only one direction. In preferred embodiments, the cushions are positioned over enlarged head portions of the distal anchors for further reducing trauma on surrounding tissue.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: June 29, 2021
    Assignee: Edwards Lifesciences CardiAQ LLC
    Inventors: J. Brent Ratz, Luca Pesce, Glen T. Rabito, Christine Thanh Nguyen
  • Patent number: 11039915
    Abstract: Apparatus and methods are described including a tube (20) that defines a flared downstream portion (30) that diverges toward a downstream end (32) of the tube, and a flared upstream portion (26) that diverges toward an upstream end (28) of the tube, such that a central portion (34) of the tube is narrower than at the ends of the tube. The tube defines a plurality of lateral openings (36). A support frame (24) supports the tube within a subject's vena cava, such that the downstream portion is sealed with respect to the wall of the vena cava downstream of junctions of the vena cava with all of the subject's renal veins, and the upstream portion is sealed with respect to the inner wall of the vena cava upstream of junctions of the vena cava with all of the subject's renal veins. Other applications are also described.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: June 22, 2021
    Assignee: MAGENTA MEDICAL LTD.
    Inventors: Yosi Tuval, Ehud Schwammenthal, Daniel Glozman, Gad Lubinsky
  • Patent number: 11033662
    Abstract: A method and device for localized treatment of tissues or organs that were exposed to ischemia and reperfusion (IR) injury, in order to reduce their structural damage and loss of function. The method further includes intra-arterial treatment of transplanted tissues or organs, which are exposed to similar damage of IR and are at risk of impaired function. Leptin antagonist is administered as a bolus injection directly into a re-opened artery, which supplies blood to the tissue or organ involved, immediately after reperfusion. In some cases, after administering a bolus injection of leptin antagonist, the effect of leptin antagonist in the involved organ can be prolonged by deploying a double function drug eluting stent, which elutes leptin antagonist into the lumen, e.g., by sustained release, while eluting antiproliferative drug into the vessel wall to prevent local stenosis, which may appear due to stent deployment.
    Type: Grant
    Filed: October 8, 2018
    Date of Patent: June 15, 2021
    Assignee: REMODELESS CV LTD
    Inventor: Jacob Schneiderman
  • Patent number: 11027046
    Abstract: A substantially fluid impermeable textile graft may be produced by selective application of a substantially water-soluble material or masking agent, and optionally selective removal of excess substantially water-soluble material, followed by the application of a substantially water-insoluble sealant. The inner surface of the graft includes a coating of the substantially water-soluble material thereon. The outer surface includes a coating of the substantially water-insoluble sealant disposed thereon. The tubular wall having the coating of the substantially water-insoluble sealant is, after curing thereof, substantially impermeable to liquid. The substantially water-soluble material is removed from the graft after the application of the substantially water-insoluble sealant.
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: June 8, 2021
    Assignee: Hothouse Medical Limited
    Inventors: David Granville Stevenson, Timothy Rawden Ashton, Brian McMurray, Chadd Clark, Lindsey Calcutt, Kayla Wilson, Josh Davidson
  • Patent number: 11020164
    Abstract: The current invention concerns systems, devices and methods for the ablation of a ablation of the wall of one or more pulmonary veins (PV) from the inside, preferably transmural ablation and preferably at the level of the antrum. Hereby, one or more implant devices can be implanted in the vessels and can subsequently be heated by external energy-providing means.
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: June 1, 2021
    Assignee: MEDICAL DEVELOPMENT TECHNOLOGIES S.A.
    Inventor: Glenn Van Langenhove
  • Patent number: 11020215
    Abstract: A venous anchor device operably coupled by graft material to form an anastomotic connector is provided. The venous anchor device includes a tubular main body having a metal frame structure and including a distal end and a proximal end, the distal end including a plurality of barbs thereon wherein said distal end has an outer diameter greater than the proximal end. The venous anchor device is fluidly connected by a graft to form an anastomotic connector.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: June 1, 2021
    Assignee: PHRAXIS, INC.
    Inventors: James V. Donadio, III, Steven E. Scott, Alexander S. Yevzlin, Robert Ziebol, Reed A. Houge, Doug S. Wahnschaffe, Steve Berhow, Jeff M. Welch
  • Patent number: 10973668
    Abstract: A valve device includes a valve, a scaffold connected coaxially to an external surface of the valve, a luminal prosthesis that is adapted to be implanted into a lumen of a patient, with the scaffold and the valve removably attachable inside of the luminal prosthesis.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: April 13, 2021
    Assignee: Coloplast A/S
    Inventor: Niall Behan
  • Patent number: 10966771
    Abstract: An expandable implant for treating bone preferably in a minimally invasive manner includes a preferably cylindrical core element extending along a longitudinal axis and preferably a plurality of nestable, expandable sleeves extending along a longitudinal axis for placement radially about the core element. The plurality of nestable sleeves are sequentially insertable over the core element in such a manner that a first nestable sleeve is inserted over the core element and each subsequently inserted nestable sleeve is received between the core element and the previously inserted nestable sleeve such that the insertion of each additional sleeve causes each previously inserted sleeve to outwardly expand.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: April 6, 2021
    Assignee: DePuy Synthes Products, Inc.
    Inventor: Harry Thomas Hall
  • Patent number: 10966813
    Abstract: Urologic stents that are adapted for temporary use to provide relief following treatments for benign prostatic hyperplasia and other disorders of the prostate, urethra and ureters.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: April 6, 2021
    Inventor: John H. Shadduck
  • Patent number: 10959715
    Abstract: The present disclosure describes medical devices comprising a bio-corrodible stent member and a graft member. The bio-corrodible stent member can comprise a metal applied directly to the graft member via a vapor deposition process, such as a chemical or physical vapor deposition process.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: March 30, 2021
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Edward H. Cully, Sherif A. Eskaros
  • Patent number: 10959845
    Abstract: An implant that includes a ring, anchors, and adjustment elements is advanced to a subject's heart valve. The ring includes hinges, and struts arranged in a pattern of alternating peaks and troughs. The ring circumscribes a central axis. At least one hinge is disposed at each trough. Each strut has a first end-portion and a second end-portion. Each peak is defined by convergence of adjacent first end-portions. Each trough is defined by convergence of adjacent second end-portions. Each anchor has a longitudinal axis. Within the heart, the longitudinal axis of at least one of the anchors is deflected with respect to the central axis, and each of the anchors is driven along its longitudinal axis with respect to the trough and into tissue of the heart. Subsequently, tissue of the heart is contracted by rotating the plurality of adjustment elements. Other embodiments are also described.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: March 30, 2021
    Assignee: Valtech Cardio, Ltd.
    Inventors: Meir Kutzik, Haim Brauon, Michael Levin, Alon Fogel, Ilia Hariton, Tal Reich
  • Patent number: 10959840
    Abstract: Systems and methods recited herein provide for affixation of a prosthetic valve to surrounding tissue, by at least one anchor and an anchor deployment device. The prosthetic valve device may be compliant with native tissue and may receive the at least one anchor in at least one anchor receptacle to affix the prosthetic valve to native tissue. The anchor may include a distal tip, a proximal head, and a tension component, such that upon deployment into tissue the tension component is situated in a tensioned state to exert a pulling force on the distal end of the anchor.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: March 30, 2021
    Assignee: MICRO INTERVENTIONAL DEVICES, INC.
    Inventor: Michael P. Whitman
  • Patent number: 10952724
    Abstract: Stapling assemblies for use with a surgical stapler and methods for manufacturing the same are provided. Three dimensional adjuncts for use with a surgical stapling assembly and methods for manufacturing the same are also provided.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: March 23, 2021
    Assignee: Ethicon LLC
    Inventors: Frederick E. Shelton, IV, Jason L. Harris, Michael J. Vendely, Peyton Hopson, Rao Bezwada
  • Patent number: 10940294
    Abstract: A balloon catheter includes an elongated catheter shaft, an expandable balloon connected to the elongated catheter shaft, and a sheath that defines a lumen and includes a therapeutic agent disposed within the lumen. The balloon catheter further includes a first configuration and a second configuration. When in the first configuration, the expandable balloon is disposed distally from the sheath such that an outer surface of the expandable balloon does not contact the lumen. Further, when in the second configuration, at least a portion of the outer surface of the expandable balloon is disposed within the lumen of the sheath such that it contacts the therapeutic agent. At least a portion of the therapeutic agent that contacts the outer surface of the expandable balloon is transferred from the lumen of the sheath to the outer surface of the expandable balloon when the balloon catheter is in the second configuration.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: March 9, 2021
    Assignee: MEDTRONIC VASCULAR, INC.
    Inventors: Shyam Nagasrinivasa, Claudio Silvestro
  • Patent number: 10932924
    Abstract: A degradation data generator is used with a scaffold for delivery within a patient. The degradation data generator includes a driving circuit electrically coupled to drive an impedance of the scaffold. A detection circuit generates degradation data based on the impedance of the scaffold or other properties such as RF or lightwave transmission, conductance or absorption. The degradation data indicates an amount of biodegradation of the scaffold. A wireless transmitter is coupled to transmit the degradation data to a wireless degradation data receiver, while the scaffold is within the patient.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: March 2, 2021
    Assignee: Memory Effect Medical, LLC
    Inventors: Christine Laramy, Bruce Stuckman
  • Patent number: 10926002
    Abstract: Orthopedic replacements include are formed at least partially of composite materials including a metal matrix with reinforcing carbon fiber integrated into the matrix. The composite materials have substantially lower density than metal, and are expected to have appreciable strength. The orthopedic replacements can include a bone attachment portion and a load bearing portion. In some versions, the orthopedic replacements can include a core formed of the composite material, with a shape completion portion, formed for example from plastic, at least partially coating the core.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: February 23, 2021
    Assignee: Toyota Motor Engineering & Manufacturing North America, Inc.
    Inventor: Michael Paul Rowe
  • Patent number: 10918504
    Abstract: Methods and devices relate to the use and construction of a vascular stent. A stent assembly includes mesh structure that is at least partially attached to a support or stent structure. The stent structure is formed of one or more struts that collectively form a tubular body sized to fit within a blood vessel. The mesh structure is formed of one or more filaments or sutures that are interwoven or knit to form a structure that is coupled to the stent structure. The mesh structure can at least partially cover or at least be partially covered by the stent structure.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: February 16, 2021
    Assignee: Silk Road Medical, Inc.
    Inventors: Michael P. Wallace, Herbert Mendoza, Roy Leguidleguid
  • Patent number: 10905541
    Abstract: An endoluminal prosthesis system for being deployed in a patient's aorta near the heart, includes a graft having a main body with a proximal end configured to be deployed near a patient's heart and a distal end configured to be deployed away from the patient's heart. The main body defines a proximal portion of the graft including the proximal end; a distal portion of the graft including the distal end; a middle portion of the graft extending between the proximal portion and the distal portion. A connection branch attached to the middle portion has an inner end attached to the middle portion and an outer end disposed radially outwardly from the inner end. The outer end of the connection branch includes a terminal ring composed of at least two partial rings pivotable relative to each other and including at least one radially outward barb.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: February 2, 2021
    Assignee: Cook Medical Technologies LLC
    Inventors: Ryan C. Bradway, Woong Kim, Jarin A. Kratzberg, Kevin D. Wilger
  • Patent number: 10905578
    Abstract: A percutaneous, transluminal, angioplasty system includes a non-foreshortening stent and a stent anchor to hold the stent in place until delivery. The stent comprises rings and fused rings comprising various motifs such as butterfly or pinched ellipsoid motifs. Stent anchors can release the stent after an outer sheath uncovers the stent or uncovers the stent and biased or bent fingers of the stent anchors.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: February 2, 2021
    Assignee: C. R. Bard, Inc.
    Inventor: Andrzej J. Chanduszko
  • Patent number: 10898266
    Abstract: For personalizing a vessel stent, images associated with a subject generated by various imaging modalities are aggregated. The images are then processed for identifying Regions of Interest (ROIs) and various parameters associated with the ROIs. Further, a model and a composition of the vessel stent to be administered to the subject to alleviate the condition in the vessel are computed. Thereafter, the model is verified for compatibility using information derived from patient stratification parameters. Upon successful verification of the model, a format of the model is generated that can be used directly for fabricating the vessel stent using additive manufacturing processes known in the art.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: January 26, 2021
    Assignee: Siemens Healthcare GmbH
    Inventors: Yogesh Bathina, Antony Louis Piriyakumar Douglas, Rajendra Prasad Jadiyappa, Amit Kale
  • Patent number: 10874606
    Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: December 29, 2020
    Assignee: Mati Therapeutics Inc.
    Inventors: Eugene de Juan, Jr., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S. Gifford, Mark Deem
  • Patent number: 10857267
    Abstract: An absorbable iron-based alloy implantable medical device includes an iron-based alloy matrix, a degradable polymer coating disposed on the surface of the iron-based alloy matrix, and a corrosion inhibition layer disposed on the surface of the iron-based alloy matrix. The corrosion inhibition layer can delay early-stage corrosion of the iron-based alloy matrix, ensure mechanical performance of a medical device in the early stage of the implantation, prevent degradation of a polymer in the early stage of the implantation of the medical device, and reduce the usage of the degradable polymer, thereby reducing risks of inflammatory reactions.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: December 8, 2020
    Assignee: LIFETECH SCIENTIFIC (SHENZHEN) CO., LTD
    Inventors: Wenjiao Lin, Li Qin, Deyuan Zhang, Hongtao Sun, Gui Zhang
  • Patent number: 10858740
    Abstract: The present disclosure presents a method and a system for modifying a surface of a substrate. The method includes an act of abrasive blasting of a part of the surface of the substrate. In the abrasive blasting, an abrasive media is provided to the part of the surface. The abrasive media is carried to the part by a first carrier. The abrasive media collides with the part of the surface and causes abrasion to the part of the surface. In the method, the first carrier includes steam. The steam of the first carrier heats the part of the surface.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: December 8, 2020
    Assignee: Siemens Aktiengesellschaft
    Inventors: Per Möller, Asger Andersen, Sara Eisenhardt, Kasper Bondo Hansen, Martin Kalmar Hansen, Melanie Thyrhaug
  • Patent number: 10849770
    Abstract: A tubular prosthesis having at least two helical loops or discrete loops, linked by a bridge, includes at least two regular struts connected by a regular inflection point forming a regular gap between the regular struts and at least two stagger struts connected by a stagger inflection point forming a stagger gap wherein the regular gap has a size different from the stagger gap.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: December 1, 2020
    Assignee: C. R. Bard, Inc.
    Inventors: Martin Schlun, Achim Zipse, Thilo Wack, Andreas Block
  • Patent number: 10842918
    Abstract: A length extensible implantable device includes a porous member and a longitudinal constraining member. The longitudinal constraining member can constrain at least a portion, up to the entire length of, the porous member in the longitudinal direction. The length of the longitudinally constrained portion can be expanded by applying force to the porous member. The porous member may be a porous tubular member.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: November 24, 2020
    Assignee: W.L. Gore & Associates, Inc.
    Inventors: Edward H. Cully, Jeffrey B. Duncan
  • Patent number: 10842620
    Abstract: A method of implanting a prosthetic heart valve includes advancing a prosthetic heart valve to an implantation location within a patient's body, positioning the prosthetic heart valve within a native heart valve annulus, expanding a frame of the prosthetic heart valve from a first contracted configuration to a first expanded configuration, and then contracting the frame to a second contracted configuration. The prosthetic heart valve may be repositioned and then re-expanded from the second contracted configuration to a second expanded configuration. The prosthetic heart valve is preferably released from the delivery apparatus while in the second expanded configuration. Releasing the prosthetic heart valve from the delivery apparatus may result in radial expansion of a flange portion of the prosthetic heart valve.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: November 24, 2020
    Assignee: Edwards Lifesciences CardiAQ LLC
    Inventors: Jorge H. Jimenez, James L. Greene
  • Patent number: 10842657
    Abstract: Disclosed herein is a stent which is compressible to small diameter and usable in neurovascular applications. The device is a braided stent and has a crown geometry which enables compression to small diameter without cracking or tangling. Also disclosed is a method of deploying a stent to a body vessel and its use in a coiling procedure.
    Type: Grant
    Filed: August 1, 2018
    Date of Patent: November 24, 2020
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventors: Melissa Lonn, Shuo Yang
  • Patent number: 10835398
    Abstract: Devices that can be delivered into a vascular system to divert flow are disclose herein. According to some embodiments, devices are provided for treating aneurysms by diverting flow. An expandable device can comprise, for example, first a plurality of strut regions and a plurality of bridge regions. Each of the bridge regions may connect a first strut of a first strut region to a second strut of a second strut region. The first strut region may comprise a first plurality of apices defining a first circumferential plane, and the second strut region may comprise a second plurality of apices defining a second circumferential plane. A first curved segment of the bridge may extend across the first circumferential plane towards the first strut region, and a second curved segment of the bridge may extend across the second circumferential plane towards the second strut region.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: November 17, 2020
    Assignee: COVIDIEN LP
    Inventor: Animesh Choubey
  • Patent number: 10828181
    Abstract: Apparatus and methods are described for use with a blood vessel of a subject. An annular antenna is placed inside the blood vessel such that radial expansion of the antenna is limited by a circumference of the blood vessel. A transmitter generates an inductive current in the antenna, by transmitting RF energy toward the antenna. A control unit measures the inductive current in the antenna, and, in response thereto, determines a physiological parameter of the subject. Other applications are also described.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: November 10, 2020
    Assignee: Enopace Biomedical Ltd.
    Inventors: Amir Dagan, Nitai Hanani, Gal Ariav, Igor Gindin, Yossi Gross
  • Patent number: 10828184
    Abstract: A vascular stent may be used to maintain or enhance patency of a blood vessel. By using multiple, separate stent elements that are balloon expandable, the multi-element stent may be stronger than a traditional self-expanding stent but may also be more flexible, due to its multiple-element configuration, than a traditional balloon-expandable stent. The stent elements are formed from a bioresorbable polymer material. The radial rigidity of the stent is configured to decrease after implantation in a vessel as the polymer is absorbed. The thickness of the stent, cell shape, polymer material, and/or treatment of the polymer material may be configured to provide a high initial radial rigidity to the vessel upon implantation and a decrease in the radial rigidity of the vessel over time.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: November 10, 2020
    Assignee: EFEMORAL MEDICAL LLC
    Inventor: Lewis B. Schwartz
  • Patent number: 10813777
    Abstract: A stent composed by a bioabsorbable network of polymer fibers that can be rearranged upon expansion, accommodating for diameter enlargement without the need of a strut or strut pattern and providing temporary support to a biological duct, is provided. Additionally, a stent is provided where the rearranged fibrous network of its expanded state can act as a scaffold for cell infiltration and promote autologous tissue formation.
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: October 27, 2020
    Assignees: STENTIT B.V., TECHNISCHE UNIVERSITEIT EINDHOVEN
    Inventors: Bart Sanders, Maria Sol Cabrera, Franciscus Petrus Thomas Baaijens, Patricia Yvonne Wilhelmina Dankers
  • Patent number: 10814046
    Abstract: Aspects include methods of fabricating antibacterial surfaces for medical implant devices including patterning a photoresist layer on a silicon substrate and etching the silicon to generate a plurality of nanopillars. Aspects also include removing the photoresist layer from the structure and coating the plurality of nanopillars with a biocompatible film. Aspects also include a system for preventing bacterial infection associated with medical implants including a thin silicon film including a plurality of nanopillars.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: October 27, 2020
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stacey M. Gifford, Huan Hu, Emily R. Kinser, Roy R. Yu, Sufi Zafar
  • Patent number: 10813740
    Abstract: An embolic protection device includes a shaft, a first magnet fixedly coupled to a distal portion of the shaft, a second magnet slidingly coupled to the shaft proximal to the first magnet, and a filter including a distal portion coupled to the first magnet and a proximal portion coupled to the second magnet. The first and second magnets are magnetically attracted to each other such that in a radially compressed configuration of the filter, the second magnet is spaced from the first magnet a first distance, and in a radially expanded configuration of the filter, the second magnet slides towards the first magnet such that the second magnet is spaced a second distance from the first magnet, wherein the second distance is smaller than the first distance.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: October 27, 2020
    Assignee: Medtronic, Inc.
    Inventors: Elizabeth Schotzko, Joel Racchini, Jeffrey Sandstrom