Stent Structure Patents (Class 623/1.15)
  • Patent number: 10433987
    Abstract: Preferred embodiments of a stent with a high degree of flexibility are shown and described. The stent can include a continuous helical winding having interconnected struts joined at vertices, and having bridges connecting sections of the helical winding to each other. An annular ring can be provided at one or both ends of the helical winding, and the annular ring can have extensions extending to connect to the helical winding. One of the extensions can connect to a bridge and another extension can connect to a vertex. The struts at the ends of the helical winding can have strut lengths that differ from the strut lengths of the struts in a central portion of the winding between the ends of the winding.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: October 8, 2019
    Assignee: C. R. Bard, Inc.
    Inventors: Thomas O. Bales, Jr., Scott L. Jahrmarkt, Charles R. Slater, Peter K. Kratsch
  • Patent number: 10433954
    Abstract: The present invention relates to a radially collapsible frame (1) for a prosthetic valve, the frame (1) comprising an outflow end region (3) at a proximal end of the frame (1) and an inflow end region (2) at a distal end of the frame (1), opposite to the outflow end region (3). The frame (1) further includes at least two radially spaced commissure attachment regions (10, 10?, 10?) and a cell structure (30), composed of a plurality of lattice cells being arranged radially around a flow axis of the frame (1) and connecting the at least two commissure attachment regions (10, 10?, 10?). Finally, at least one anchoring/positioning arch (20, 20?, 20?) is provided, wherein said at least one anchoring/positioning arch (20, 20?, 20?) radially overlaps the cell structure (30) at least partially.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: October 8, 2019
    Assignee: JenaValve Technology, Inc.
    Inventors: Michael J. Girard, Martin Schlun
  • Patent number: 10426592
    Abstract: Medical devices and methods for making and using a medical device are disclosed. An example medical device may include a stent that comprises a first covered region formed of one or more interwoven filaments and a covering. The stent may also comprise a second uncovered region adjacent the first covered region. The second uncovered region may include a knitted filament. A first end of the knitted filament may be attached to the first covered region. The knitted filament is configured to be unraveled to remove both the first covered region and the second uncovered region of the stent while the first end of the knitted stent remains attached to the first covered region.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: October 1, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Martyn G. Folan, Thomas M. Keating
  • Patent number: 10420862
    Abstract: Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms are disclosed. The systems include an insertable medical device and an in-situ forming foam that is formed from a polymer that reacts in an aqueous environment. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: September 24, 2019
    Assignee: Aresenal AAA, LLC.
    Inventors: Upma Sharma, Gregory Zugates, Rany Busold, Toby Freyman
  • Patent number: 10390930
    Abstract: An aortic graft assembly includes a tubular component that defines a wall aperture having a proximal end that extends perpendicular to a major longitudinal axis of the tubular aortic component, and a tunnel graft connected to the wall of the tubular aortic component and extending from the wall aperture toward a proximal end of the tubular aortic component. The method for delivery of the aortic graft assembly includes delivering the aortic graft assembly through the wall aperture and into interfering relation with the tunnel graft.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: August 27, 2019
    Assignee: Bolton Medical, Inc.
    Inventors: Samuel Arbefeuille, Fletcher Christian, Joseph A. Manguno, Jr., John C. Canning
  • Patent number: 10390978
    Abstract: Preferred embodiments of a stent with a high degree of flexibility are shown and described. The stent can include a continuous helical winding and at least one bridge. The continuous helical winding has a plurality of circumferential sections that circumscribe a longitudinal axis from a first end to a second end to define a tube. The circumferential sections are spaced apart along the axis. The at least one bridge is configured to connect one circumferential section to an axially-spaced adjacent circumferential section. The at least one bridge extends on a plane generally orthogonal with respect to the axis.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: August 27, 2019
    Assignee: Angiomed GmbH & Co. Medizintechnik KG
    Inventors: Thomas O. Bales, Jr., Scott L. Jahrmarkt, Charles R. Slater, Peter K. Kratsch
  • Patent number: 10383749
    Abstract: Stents and method of inserting a stent into a delivery catheter are disclosed. In a disclosed embodiment, a stent for redirecting blood flow away from an aneurysmal sac is provided. The stent comprises an elongate frame that is radially contractable from a fully radially expanded state to a radially contracted state in a process involving elongation of the frame, wherein: the fully radially expanded state represents the state of the frame at body temperature when no external force is applied to the frame; in the radially contracted state the frame has a maximum lateral dimension that is at least 30% smaller than the maximum lateral dimension of the frame in the fully radially expanded state; and the frame comprises a low porosity region for positioning at the opening to the aneurysmal sac, the low porosity region having a porosity of less than 50% when the frame is in the fully radially expanded state.
    Type: Grant
    Filed: April 5, 2016
    Date of Patent: August 20, 2019
    Assignee: Oxford University Innovation Limited
    Inventors: Xiang Zhou, Zhong You, James Byrne
  • Patent number: 10376354
    Abstract: A joining arrangement between a main tube (3) and a side arm (5) in a side arm stent graft (1). The side arm (5) is stitched into an aperture (11) in the main tube and is in fluid communication with it. The aperture is triangular, elliptical or rectangular and the side arm is cut off at an angle to leave an end portion having a circumferential length equal to the circumference of the aperture. The side arm can also include a connection socket (76) comprising a first resilient ring (79) around the arm at its end, a second resilient ring (80) spaced apart along the arm from the first ring and a zig zag resilient stent (82) between the first and second rings. The zig-zag resilient stent can be a compression stent. Both the main tube and the side arm are formed from seamless tubular biocompatible graft material.
    Type: Grant
    Filed: September 2, 2015
    Date of Patent: August 13, 2019
    Assignee: Cook Medical Technologies LLC
    Inventor: David Ernest Hartley
  • Patent number: 10376397
    Abstract: The present invention relates to tissue-supporting medical devices and drug delivery systems, and more particularly to tubular flexible stents that are implanted within a body lumen of a living animal or human to support the organ, maintain patency and/or deliver drugs or agents. The tubular flexible stent has a cylindrical shape defining a longitudinal axis and includes a helical section having of a plurality of longitudinally oriented strut members and a plurality of circumferentially oriented hinge members connecting circumferentially adjacent strut members to form a band. The band is wrapped about the longitudinal axis in a substantially helical manner to form a plurality of helical windings. At least one connector member extends between longitudinally adjacent helical windings of the band.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: August 13, 2019
    Assignee: CARDINAL HEALTH SWITZERLAND 515 GMBH
    Inventors: Ryan Donovan, John F. Shanley, Prasanna Muralidharan, David W. Overaker, Ramesh Marrey, Robert Burgermeister
  • Patent number: 10376361
    Abstract: Apparatus is provided for use with a native valve of a heart of a subject. The apparatus includes: (1) an annular upstream support portion, comprising an expandable first frame, the upstream support portion configured to be placed against an upstream surface of the native valve; (2) a flexible polyester connector; and (3) an anchoring element, flexibly coupled to the upstream support portion by the connector, and configured to anchor the upstream support portion to the native valve by engaging tissue of the native valve.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: August 13, 2019
    Assignee: CARDIOVALVE LTD.
    Inventors: Yossi Gross, Gil Hacohen, Eran Miller, Yuval Zipory
  • Patent number: 10369029
    Abstract: There is disclosed a method of treating hypoxia in tissue of a blood vessel, the method comprising placing a stent in the vessel, the stent having a center line which curves in three dimensions to promote the supply of oxygen from the blood flowing in the lumen of the stented vessel to the vessel wall. There is disclosed a method of treating a subject with diabetic atherosclerosis, the method comprising placing a stent in a blood vessel of the subject, the stent having a center line which curves in three dimensions to promote the supply of oxygen from the blood flowing in the lumen of the stented vessel to the vessel wall.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: August 6, 2019
    Assignee: Veryan Medical Limited
    Inventors: Colin Gerald Caro, Martin G. Burke, Paul Gilson, Kevin B. Heraty, Nicholas Yeo
  • Patent number: 10368990
    Abstract: A prosthetic mitral valve includes an anchor assembly, a strut frame, and a plurality of replacement leaflets secured to the annular strut frame. The anchor assembly includes a ventricular anchor, an atrial anchor, and a central portion therebetween. The ventricular anchor and the atrial anchor are configured to flare radially outwards relative to the central portion. The annular strut frame is disposed radially within the anchor assembly and is attached to the anchor assembly. The central portion is configured to align with a native valve orifice and the ventricular anchor and the atrial anchor are configured to compress native cardiac tissue therebetween.
    Type: Grant
    Filed: June 19, 2018
    Date of Patent: August 6, 2019
    Assignee: Cephea Valve Technologies, Inc.
    Inventors: Spencer Noe, Dan Wallace, Jonathan Oakden
  • Patent number: 10368983
    Abstract: A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, and a plurality of commissure features disposed between the proximal end and the distal end. The stent includes a plurality of struts, selected ones of the struts having multiple widths along their length and being wider adjacent the commissure features than at locations spaced away from the commissure features. A collapsible and expandable valve assembly includes a plurality of leaflets connected to the plurality of commissure features.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: August 6, 2019
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventor: Kristopher Henry Vietmeier
  • Patent number: 10364487
    Abstract: The present invention relates to a high entropy alloy having more improved mechanical properties by controlling contents of additive elements in a NiCoFeMnCr 5-element alloy to control stacking fault energy, thereby controlling stability of a ? austenite phase to control a transformation mechanism, wherein the stacking fault energy is controlled in a composition range of NiaCobFecMndCre (a+b+c+d+e=100, 1?a?50, 1?b?50, 1?c?50, 1?d?50, 10?e?25, and 77a?42b?22c+73d?100e+2186?1500), and thus, the ? austenite phase exhibits a twin-induced plasticity (TWIP) property or a transformation induced-plasticity (TRIP) property in which the ? austenite phase is subjected to phase transformation into an ? martensite phase or an ?? martensite phase, under stress, thereby having improved strength and elongation at the same time to have excellent mechanical properties.
    Type: Grant
    Filed: February 9, 2017
    Date of Patent: July 30, 2019
    Assignee: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Eun Soo Park, Hyun Seok Oh, Sangjun Kim, Kooknoh Yoon, Chae Woo Ryu
  • Patent number: 10349947
    Abstract: The present disclosure provides occlusion devices which comprise (a) a self-expanding support frame having a longitudinal axis comprising a plurality of loops each having an orifice, the support frame being self-expandable from a constrained shape to an unconstrained shape, and (b) a covering material covering an orifice of at least one of the loops. Also provided are assemblies and kits that contain such occlusion devices, and methods of delivering such occlusion devices to a patient.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: July 16, 2019
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Patrick A. Haverkost, Joseph Michael Connolly, Joel N. Groff
  • Patent number: 10342685
    Abstract: A stent includes a series of helical windings defining an outer circumference of a cylinder. The helical windings include a plurality of struts having straight portions connected by curved portions. The straight portions may be substantially aligned with a longitudinal axis of the stent when the stent is in a reduced state. A plurality of bridges connect adjacent windings. The bridges may be substantially orthogonal to the longitudinal axis of the stent in the reduced state. A plurality of radiopaque members extend from a terminal helical winding. The radiopaque members include an extension portion and an end portion. The extension portion may have a first width and the end portion may have a second width greater than the first width. The end portion may include an extreme end substantially orthogonal to the longitudinal axis of the stent.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: July 9, 2019
    Assignee: Angiomed GmbH & Co. Medizintechnik KG
    Inventors: Thomas O. Bales, Jr., Charles R. Slater, Scott Jahrmarkt
  • Patent number: 10335153
    Abstract: Implantable therapeutic devices and methods for endovascular placement of devices at a target site, such an opening at a neck of an aneurysm, are disclosed. Selected embodiments of the present technology have closures that at least partially occlude the neck of an aneurysm to stabilize embolic or coagulative treatment of the aneurysm. In one embodiment, for example, an aneurysm closure device comprises a closure structure and a supplemental stabilizer. The closure structure can have a curved portion configured to extend along a first vessel, such as a side branch of a bifurcated vessel that extends along a lateral axis. The supplemental stabilizer extends from the closure structure along a longitudinal axis transverse to the lateral axis of the first vessel. The supplemental stabilizer is configured to exert an outward force against a second vessel, such as a parent vessel, that extends transversely to the first vessel.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: July 2, 2019
    Assignee: PULSAR VASCULAR, INC.
    Inventors: Gilbert Clarke, Brent Gerberding, Robert M. Abrams, Masoud Molaei
  • Patent number: 10335298
    Abstract: The invention relates to a medical device and a method of using it. The device is a stent which can be percutaneously deliverable with (or on) an endovascular catheter or via other surgical or other techniques and then expanded. The stent is configured to have a central portion defined by “open” cells and at least two end portions, defined by “closed” cells, spaced apart and directly connected to the distal and proximal ends of the central portion of the stent. The stent may also optionally have a covering or a lattice with openings.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: July 2, 2019
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Joseph R. Armstrong, Edward H. Cully, Michael W. Franklin, Mark Y. Hansen, Brandon A. Lurie, Craig R. McMurray, William D. Montgomery, Wendy J. Terry, Eric M. Tittelbaugh
  • Patent number: 10335259
    Abstract: The present invention relates to implantable endoluminal prosthesis for preventing stroke. The endoluminal prosthesis (1) consists of a braided framework (20) defining a cylindrical lumen (21) devoid of impermeable membrane. Said braided framework (20) is self-expandable comprising a plurality of layers (22, 23, 24) of wires (25) made of biocompatible material. Each layer forms a mesh. The meshes form a lattice with a plurality of wires (2) of given layers (22, 23, 24). The lattice defines polygonal opening units (26) when observed normal to a wall of the implantable endoluminal prosthesis (1). The diameter (Ø25) of wire (25) being at least 30 ?m and at most 150 ?m, the mean diameter (Ø27) of the inscribed circle (27) of the polygonal opening units (26) being at least 75 ?m and at most 200 ?m in fully expanded state. The braided framework (20) consists of at least 128 and at most 512 wires (25).
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: July 2, 2019
    Assignee: FRID MIND TECHNOLOGIES
    Inventor: Noureddine Frid
  • Patent number: 10322017
    Abstract: A medical implant such as a self-expanding shape memory alloy stent with a strut matrix formed by cut patterns in a wall of a tubular workpiece can be enhanced by arranging for the line of the laser beam when cutting the struts to be one that does not pass through the longitudinal rotational axis of the tubular workpiece. Such “off-axis” cutting can modify the cross-sectional shape and area of each strut, along its length. Such modulation can enhance the fatigue resistance of the stent matrix, or increase the radial force that the stent matrix is capable of exerting on bodily tissue within which it is implanted.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: June 18, 2019
    Assignee: Angiomed GmbH & Co. Medizintechnik KG
    Inventor: Thiemo Blank
  • Patent number: 10314703
    Abstract: Disclosed herein are embodiments of a balloon shaped to have one or more enlarged regions to selectively increase expansion forces on an implant. For example, the balloon may have a central portion that is enlarged to exert more force on the center of a stent-mounted prosthetic heart valve. This overcomes the stent-mounted prosthetic heart valve's tendency to expand with flared ends. This forms a more cylindrical or barrel shaped stent frame during expansion of the balloon—reducing or eliminating the instance wherein the cylindrical stent frame has flared ends. Alternatively, the balloon may have conical flares placed to cause or enhance flared ends of the cylindrical implant to enhance its anchoring capabilities.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: June 11, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: David Maimon, Michael R. Bialas, Mindy Lee Ann Black, Tamir S. Levi, Linda Thai, Yidong M. Zhu
  • Patent number: 10292854
    Abstract: Devices and methods can be used for the endoscopic treatment of conditions such as obesity and metabolic diseases. For example, this document provides devices and methods for bypassing portions of the gastrointestinal tract to reduce nutritional uptake. The devices provided herein can be endoscopically implanted such that direct visualization of the entire implant location within the gastrointestinal tract is attained. In some embodiments, the device is distally deployed utilizing a technique that is like that of single or double-balloon enteroscopy.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: May 21, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Barham K. Abu Dayyeh
  • Patent number: 10292813
    Abstract: Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.
    Type: Grant
    Filed: December 7, 2016
    Date of Patent: May 21, 2019
    Assignee: St. Jude Medical, LLC
    Inventors: Peter N. Braido, Andrea L. McCarthy, Rubem L. Figueiredo, Julia Schraut
  • Patent number: 10286120
    Abstract: In-vivo biodegradable medical implants, containing at least in part at least partially fine-grained metallic materials provide a strong, tough, stiff and lightweight implant. The in-vivo biodegradable implants are used in a number of stent applications, for fracture fixation, sutures and the like. The in-vivo biodegradable medical implants enable the reduction of implant size and weight and consequently result in reducing the release of implant degradation products into the body.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: May 14, 2019
    Assignee: INTEGRAN TECHNOLOGIES, INC.
    Inventors: Klaus Tomantschger, Gino Palumbo, Diana Facchini
  • Patent number: 10285809
    Abstract: An implant system may include a delivery sheath having an actuator mechanism, an anchoring assistance device including an expandable scaffold including a mid-body section, a cusp interface section, and a crown end arrangement, and a replacement heart valve implant. The cusp interface section includes a plurality of loop portions arranged at radial intervals about the expandable scaffold. Each loop portion is circumferentially spaced apart from another loop portion by a region having a deployment ring, the region being configured to span a commissure of the aortic valve and extending distally a shorter distance from the distal end than the loop portions. An elongate deployment member is configured to releasably engage with the deployment rings to actuate the expandable scaffold from a delivery configuration to a deployed configuration. The replacement heart valve implant is configured to be at least partially disposed within the expandable scaffold in the deployed configuration.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: May 14, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED INC.
    Inventors: Martyn G. Folan, Juan F. Granada
  • Patent number: 10285832
    Abstract: A system for treating a bifurcation includes first and second delivery catheters. The first catheter has a first shaft, a first expandable member adjacent the distal end of the first shaft, an auxiliary expandable member disposed under the first expandable member, and a first radially expandable stent disposed over both the first expandable member and the auxiliary expandable member. The second delivery catheter has a second shaft, and a second expandable member adjacent the distal end of the second shaft. A portion of the second catheter is disposed under a portion of the first stent, and a portion of the second delivery catheter passes through a side hole in the first stent. The first stent is crimped over the first and second catheters such that the first stent remains attached to the first and the second catheters during advancement of the catheters through a blood vessel.
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: May 14, 2019
    Assignee: Advanced Bifurcation Systems Inc.
    Inventor: Henry Bourang
  • Patent number: 10272183
    Abstract: The present invention relates to an implant, in particular an intraluminal endoprothesis, comprising a body containing a metallic material, and comprising at least one functional element that is fastened to the body and has a material composition in at least a portion of its volume that differs from the material of the body, the material composition preferably including radio-opaque and/or x-ray opaque material. To effectively prevent accelerated degradation due to the formation of a local cell of the material of the body and the functional element, the at least one functional element includes a first layer at least in the region of its surface where it is bonded to the body, the first layer primarily containing at least one metal oxide. Furthermore, the manufacture of an implant of this type is described.
    Type: Grant
    Filed: June 20, 2011
    Date of Patent: April 30, 2019
    Assignee: BIOTRONIK AG
    Inventors: Ullrich Bayer, Wolfgang Schultz, Nils Venohr, Johannes Riedmueller, Martina Schroeder
  • Patent number: 10271974
    Abstract: A helical stent is provided that is wound in a zig-zag pattern along a pitch angle with respect to a plane transverse to the axis of the stent. A bisecting line extending through a bend and between two adjacent angular struts is also angled with respect to the longitudinal axis of the stent.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: April 30, 2019
    Assignee: Cook Medical Technologies LLC
    Inventors: Siddharth U. Vad, Mark R. Frye, Sean D. Chambers
  • Patent number: 10271971
    Abstract: Provided is a thin, narrow tube for use in a biodegradable medical device formed from a round tube made of a magnesium material as the base material, in which a desired outer diameter and an inner diameter are provided with good precision over the entire region in a longitudinal direction and a circumferential direction, and the length of biodegradation time can be controlled without changing a material composition. The thin, narrow tube is a thin, narrow tube of a biodegradable medical device, in which the thin, narrow tube is a round tube made of crystals containing magnesium (Mg) having a hexagonal crystal structure, and when the crystals forming the round tube are viewed in a round tube axis direction of the round tube, a hexagonal basal plane (0001) is oriented at a predetermined inclination angle with respect to a circumferential direction perpendicular to a radial direction (a direction from an inner surface to an outer surface) of the round tube.
    Type: Grant
    Filed: August 2, 2013
    Date of Patent: April 30, 2019
    Assignee: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Kotaro Hanada, Kunio Matsuzaki
  • Patent number: 10251972
    Abstract: A wound dressing and a method for production thereof. The wound dressing includes a collagen-containing sheet-like structure, which is made of magnesium or a magnesium alloy. The sheet-like structure has openings and is embedded in a collagen-containing sheet-like structure. The wound dressing is embodied as a geometrically stable bioresorbable membrane and includes a support made of a collagen membrane, on which the collagen-containing sheet-like structure is arranged.
    Type: Grant
    Filed: January 11, 2016
    Date of Patent: April 9, 2019
    Assignee: BOTISS BIOMATERIALS GMBH
    Inventors: Oliver Bielenstein, Drazen Tadic
  • Patent number: 10232092
    Abstract: Provided herein are devices comprising a stent; and a coating on said stent comprising a polymer and an active agent, wherein the active agent comprises at least one of: extracellular matrix and an extracellular matrix component. Provided herein are methods of preparing a device comprising a stent and a coating on said stent; said method comprising: providing a stent; and forming a plurality of layers on said stent; wherein the coating comprises a polymer and at least one of said layers comprises one or more active agents; wherein at least a portion of the active agent comprises at least one of extracellular matrix and an extracellular matrix component.
    Type: Grant
    Filed: April 20, 2011
    Date of Patent: March 19, 2019
    Assignee: Micell Technologies, Inc.
    Inventors: James B. McClain, Arthur J. Benvenuto
  • Patent number: 10232091
    Abstract: Provided are a stent in which a surface of a stent strut is treated by femtosecond laser radiation and is modified by a natural polymer and a method of preparing the stent. The stent and the preparing method may inhibit restenosis and stimulate reendothelialization.
    Type: Grant
    Filed: December 27, 2016
    Date of Patent: March 19, 2019
    Assignees: CHONNAM NATIONAL UNIVERSITY HOSPITAL, JEONNAM TECHNOPARK
    Inventors: In Ho Bae, Dae Sung Park, So Youn Lee, Eun Jae Jang, Jae Won Shim, Kyung Seob Lim, Jun Kyu Park, Kwang Hwan Oh, Myung Ho Jeong
  • Patent number: 10233427
    Abstract: The development and construction of implantable artificial organs, and a process for manufacturing three-dimensional polymer microscale and nanoscale structures for use as scaffolds in the growth of biological structures such as hollow organs, luminal structures, or other structures within the body are disclosed.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: March 19, 2019
    Assignee: NANOFIBER SOLUTIONS, LLC
    Inventor: Jed Johnson
  • Patent number: 10231855
    Abstract: The present invention relates to tubular stents that are implanted within a body lumen. The stent has a cylindrical shape defining a longitudinal axis and includes a helical section and a closed endless ring section within the helical section. The helical section has of a plurality of longitudinally oriented strut members and a plurality of circumferentially oriented hinge members connecting circumferentially adjacent strut members to form a band, the band being wrapped about the longitudinal axis in a substantially helical manner to form a plurality of helical windings. The closed ring section interrupts the repeating helical pattern and separates the helical section into a proximal helical section and a distal helical section. The intermediate ring section includes a plurality of longitudinally oriented strut members and a plurality of circumferentially oriented hinge members connecting circumferentially adjacent strut members to form an endless ring.
    Type: Grant
    Filed: August 2, 2011
    Date of Patent: March 19, 2019
    Assignee: CARDINAL HEALTH SWITZERLAND 515 GMBH
    Inventor: Valeska Schroeder
  • Patent number: 10226335
    Abstract: A mitral valve implant includes a force-expanding mitral valve lattice having an interior orifice and a self-expanding valve trampoline attached at the interior orifice of the force-expanding mitral valve lattice. The mitral valve lattice is self-expandable to a first configuration and force expandable from the first configuration to a second configuration. The configurations can be circular or D-shaped. The mitral valve lattice comprises jack screws adjusting configurations of the mitral valve lattice. The valve trampoline has a cylindrical central region comprising valve leaflets. An outwardly flaring implant skirt is attached to the mitral valve lattice exterior. Wall-retaining wires are attached to the mitral valve lattice, are petal-shaped, and have a pre-set, radially outward, memory shape. The wires and skirt impart a force on a respective side of the native mitral valve when the mitral valve lattice is expanded within an annulus of the native mitral valve.
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: March 12, 2019
    Assignee: Edwards Lifesciences CardiAQ LLC
    Inventors: Richard Cartledge, Derek Dee Deville, Kevin W. Smith, James L. Greene, Jorge Jimenez
  • Patent number: 10213326
    Abstract: An endovascular prosthesis and method of constructing a prosthesis device for implantation into the lumen of a body vessel. The endovascular prosthesis includes a fenestration in the device surrounded by an inner edge, and the inner edge further surrounded by an outer edge of larger diameter. A shaped protrusion of semi-rigid graft material spans the distance between the inner edge and the outer edge connecting the two edges. The shape protrusion has a surface area larger than the plane of the tubular body between the edges and therefore will have excess material. This excess material allows the inner edge and the fenestration to move within the circumference of the outer edge. The shaped protrusion may also form a semi-rigid dome.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: February 26, 2019
    Assignee: Cook Medical Technologies LLC
    Inventors: Brandon Davis, Matthew S. Huser, Jarin Kratzberg, Kimberly Ringenberger
  • Patent number: 10213328
    Abstract: A method of making an implantable medical device includes extruding a first ePTFE tube and a second ePTFE tube, cutting a plurality of slits in the first ePTFE tube, positioning a radially expandable support layer between the first and second ePTFE tubes so that the slits span portions of the support layer, and laminating the first ePTFE tube to the second ePTFE tube through openings in the support layer.
    Type: Grant
    Filed: December 12, 2013
    Date of Patent: February 26, 2019
    Assignee: Bard Peripheral Vascular, Inc.
    Inventors: Richard E. Layne, Sandra M. Cundy, Debra A. Bebb
  • Patent number: 10201639
    Abstract: Disclosed are medical implants for placement within a lumen of a patient. The implants comprise a polymer and drug-coated metal structure having a tubular configuration and designed to deliver the drug to target tissue at tailored linear drug elution rate.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: February 12, 2019
    Assignee: 480 Biomedical, Inc.
    Inventors: Danny Concagh, Changcheng You
  • Patent number: 10195027
    Abstract: A heart valve system, the system including a radially self-expandable tubular body and a valve. The tubular body having an inflow end and an outflow end such that the outflow end includes a proximal section and a plurality of beams. The plurality of beams being disposed distally of the proximal section in an outflow direction. Additionally, the tubular body including struts with peaks and valleys at the inflow end of the tubular body such that the proximal section of the outflow end is disposed distally of the peaks and valleys in the outflow direction. Furthermore, the tubular body being configured such that movement of the proximal section of the outflow end radially inward causes the inflow end to flare radially outward, and an arrangement of the struts being configured such that movement of the peaks radially inward causes the valleys to flare radially outward.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: February 5, 2019
    Assignee: HIGHLIFE SAS
    Inventor: Malek Nasr
  • Patent number: 10188375
    Abstract: Several unique intra-cardiac pressure vents, placement catheters, methods of placement and methods of treating heart failure are presented. The intra-cardiac pressure vents presented remain partially open under normal intra-cardiac pressures to allow sufficient flow from the left atrium to the right atrium to enable the relief of elevated left atrial pressure and resulting patient symptoms, and also limit the amount of flow from the right atrium to the left atrium by closing when the pressure in the right atrium exceeds the pressure in the left atrium by a predetermined amount.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: January 29, 2019
    Assignee: Corvia Medical, Inc.
    Inventors: Edward McNamara, David Celermajer, Stephen J. Forcucci, Hiroatsu Sugimoto, Matthew J. Finch
  • Patent number: 10184195
    Abstract: A knitted component may include a knit element that has an auxetic portion configured to move between a first position and a second position as the knitted component stretches. The knitted component may also include a tensile strand inlaid within at least one of a course and a wale of the knit element, where the tensile strand extends through the auxetic portion, and where the tensile strand is selectively securable to the knit element via a securement device. The securement device may be spaced from the auxetic portion.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: January 22, 2019
    Assignee: NIKE, Inc.
    Inventors: Tory M. Cross, Daniel A. Podhajny
  • Patent number: 10172735
    Abstract: A device for treating obesity by limiting absorption of food through a wall of a duodenum of a patient including a sleeve inserted into the duodenum of a patient. The sleeve includes a plurality of first blocking areas and a plurality of first food absorption areas, the first blocking areas providing duodenum wall covers to prevent food absorption through the duodenum wall and the first blocking areas together defining a first total blocking area. The first food absorption areas providing access to the duodenum wall to enable food absorption through the duodenum wall and the first food absorption areas together defining a first total absorption area.
    Type: Grant
    Filed: February 21, 2015
    Date of Patent: January 8, 2019
    Assignee: Rex Medical, L.P
    Inventor: James F. McGuckin, Jr.
  • Patent number: 10159537
    Abstract: The present invention provides a human tissue radiation protector with auxiliary method of radiotherapy, wherein said human tissue radiation protector comprises an interconnected expander, a syringe and a marker set onto the expander; said marker is made of radiopaque materials, which could assist the expander in positioning; as well as multiple radiation dosage detector capable of measurement the radiation dosage at different positions of the expander; said method allows to place the expander of the human tissue radiation protector between the tumor and nearby human tissues or organs so as to separate them, and assist the expander in positioning via the marker and measurement the radiation dosage via the radiation dosage detector.
    Type: Grant
    Filed: August 9, 2016
    Date of Patent: December 25, 2018
    Inventor: Hsiao-Hsu Cheng
  • Patent number: 10154916
    Abstract: A support structure includes strut members interconnected by rotatable joints to form a series of linked scissor mechanisms. The structure can be remotely actuated to compress or expand its shape by adjusting the scissor joints within a range of motion. In particular, the support structure can be repositioned within the body lumen or retrieved from the lumen. The support structure can be employed to introduce and support a prosthetic valve within a body lumen.
    Type: Grant
    Filed: April 4, 2016
    Date of Patent: December 18, 2018
    Assignee: Edwards Lifesciences CardiAQ LLC
    Inventor: Jennifer K. White
  • Patent number: 10149789
    Abstract: A material engagement element sheet formed from a sheet material (10) incorporates a pattern of material engagement element slots (14), each slot containing an array of material engagement elements (20) which have a tapered distal section (30), a flange section (34) and a proximal section (32) which is attached to an edge of the slots in the sheet material.. The material engagement element sheet material may be a single layer of shape memory material, or the sheet material may be a composite of different layers some of which may include pre-strained shape memory materials with distinguishable activation parameters. The material engagement element slot configuration allows for the simultaneous processing of the material engagement elements. The material engagement elements may be processed such that they are in a state that is substantially perpendicular to the surface of the material engagement element sheet.
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: December 11, 2018
    Assignee: MicoKoll, Inc.
    Inventor: Steven Craig Anderson
  • Patent number: 10137013
    Abstract: An endoluminal device can be configured for precise positioning during deployment within a vessel. The endoluminal device can be a tack, stent, vascular implant or other type of implant. The endoluminal device can have circumferential member with an undulating configuration having multiple inward and outward apexes and struts extending therebetween. Two of the struts can be used to establish a foot for the precise positioning of the device during deployment. A method of placing the endoluminal device can include withdrawing an outer sheath such that a portion of the endoluminal device is expanded prior to the rest of the endoluminal device.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: November 27, 2018
    Assignee: Intact Vascular, Inc.
    Inventors: Robert Giasolli, Peter Schneider
  • Patent number: 10130350
    Abstract: The pupil expander 1 of the present invention is used to maintain a pupil in an expanded state during ophthalmologic surgery such as, e.g., cataract surgery. The pupil expander 1 is equipped with four arm sections 10 arranged serially in a manner as to form a circular shape as a whole and joint sections 20 which connect end sections of adjacent arm sections in a movable manner. With this, since the end sections of adjacent arm sections 10 are connected in a movable manner and therefore the entire shape of the pupil expander 1 can be deformed in an eye via the joint section 20, the pupil expander can be arranged safely without damaging an iris I, which enables easy and assured maintenance of a sufficiently expanded state of a pupil.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: November 20, 2018
    Assignee: Junsuke Akura
    Inventor: Junsuke Akura
  • Patent number: 10117763
    Abstract: A stent of the present disclosure has a variable radial force along the longitudinal length of the stent. In particular, the radial force of the center is greater than the radial force of the ends of the stent. Without being bound by theory, the radial force is affected by the strut angle ?, the wall thickness t, the number of strut pairs, and combinations thereof. In one aspect of the present disclosure, the stent has a variable strut angle ?, a variable wall thickness t, and a variable number of strut pairs. By adjusting the strut angle ?, the wall thickness t, and the number of strut pairs of the serpentine bands, the stent will have a variable radial force without the need for additional processing steps.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: November 6, 2018
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Sean P. Fleury, Dane T. Seddon, Barry Weitzner
  • Patent number: 10117762
    Abstract: An endoluminal device can be configured for precise positioning during deployment within a vessel. The endoluminal device can be a tack, stent, vascular implant or other type of implant. The endoluminal device can have circumferential member with an undulating configuration having multiple inward and outward apexes and struts extending therebetween. Two of the struts can be used to establish a foot for the precise positioning of the device during deployment. A method of placing the endoluminal device can include withdrawing an outer sheath such that a portion of the endoluminal device is expanded prior to the rest of the endoluminal device.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: November 6, 2018
    Assignee: Intact Vascular, Inc.
    Inventors: Robert Giasolli, Peter Schneider
  • Patent number: 10098651
    Abstract: Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a fenestrated structure, a substantially cylindrical portion formed of a net-like filament mesh structure having a proximal end coupled to a distal end of the fenestrated structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction device by stacking a portion of the net-like filament mesh structure outside of the catheter by distally advancing the self-expanding member until the self-expanding member is beyond a distal end of the catheter; retracting the self-expanding member to unstack the portion of the net-like filament mesh structure and to capture the portion of the thrombus; and withdrawing the thrombus extraction device from the body.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: October 16, 2018
    Assignee: Inari Medical, Inc.
    Inventors: Phil Marchand, Benjamin E. Merritt, John C. Thress, Jacob F. Louw, Paul Lubock, Brian J. Cox