Abstract: A system for treating a bifurcation includes first and second delivery catheters, each having an expandable member and a stent. The stent on the second delivery catheter has a side hole. A portion of the first delivery catheter is disposed under a portion of the stent on second delivery catheter. The first delivery catheter is slidable relative to the second delivery catheter, and the first delivery catheter passes through the side hole.

Abstract: A prosthetic valve assembly includes a support structure and a valve component. The support structure includes a first frame and a sealing member. The first frame includes a lumen extending between inflow and outflow ends. The sealing member extends inwardly into the lumen of the first frame and includes a first end wall defining a first orifice, a second end wall axially spaced from the first end wall and defining a second orifice, and an inner sleeve extending axially from the first end wall to the second end wall and spaced radially inwardly from the first frame. The valve component includes a second frame and a valve structure supported inside of the second frame for permitting blood flow through the valve component in one direction and blocking blood flow in the opposite direction. The valve component is configured to expand within and engage the inner sleeve of the sealing member.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that include a cord that is flexible and elongated defining a length. The cord may include a core having a porous surface and a porosity-reducing element on at least a portion of the core.

Abstract: An endovascular system includes an elongate delivery shaft assembly, which, when a stent-graft is removably constrained in a radially-compressed delivery state along a distal end portion of the delivery shaft assembly, is shaped so as to define a self-orienting portion, which is shaped so as to define (a) at least proximal and distal curved portions, the proximal curved portion disposed more proximal than the distal curved portion, and (b) at least one point of inflection on a central longitudinal axis of the delivery shaft assembly longitudinally between the proximal and the distal curved portions. Upon positioning of a distal tip of the system near a bifurcation of a brachiocephalic artery from an aortic arch, the self-orienting portion automatically rotationally orients itself in the aortic arch to a rotational orientation in which an inferior lateral opening of the stent-graft faces upstream in the aortic arch. Other embodiments are also described.

Abstract: The vascular prosthesis includes a luminal graft component having at least one fenestration. At least one fenestration ring borders the at least one fenestration and is fixed to the luminal graft component. The fenestration ring includes a main component with two opposing ends and a connecting component. The diameter of the fenestration ring can expand upon insertion of a branch prosthesis through the fenestration ring during implantation at a surgical site. The vascular prosthesis can be implanted in a patient to thereby treat, for example, an arterial aneurysm, spanning a region of an aneurysm that includes at least one arterial branch.

Abstract: A method and devices for relieving pressure in the left atrium of a patient's heart is disclosed. The method includes using an ablative catheter in a minimally invasive procedure to prepare an opening from the coronary sinus into a left atrium of the patient's heart. Once the opening is prepared, the opening may be enlarged by a technique such as expanding a balloon within the opening. A stent is then placed within the coronary sinus of the patient, with a transverse portion expanding within the opening, allowing blood to flow from the left atrium to the coronary sinus and then to the right atrium. Pressure within the left atrium is thus relieved.

Abstract: A prosthetic assembly configured for endovascular placement within an aortic arch and method of use thereof. The prosthetic assembly includes a proximal aortic stent-graft prosthesis configured to be positioned within a proximal portion of the aortic arch adjacent to the brachiocephalic artery, a distal aortic stent-graft prosthesis configured to be positioned within a distal portion of the aortic arch adjacent to the left subclavian artery, a first branch stent-graft prosthesis configured to be positioned within the brachiocephalic artery and a second branch stent-graft prosthesis configured to be positioned in one of the left common carotid and the left subclavian artery. When deployed, a proximal end of the first branch stent-graft prosthesis is disposed within a lumen of the proximal aortic stent-graft prosthesis to proximally displace the ostium of the brachiocephalic artery.

Abstract: A system for treating a bifurcation includes first and second delivery catheters. The first catheter has a first shaft, a first expandable member adjacent the distal end of the first shaft, an auxiliary expandable member disposed under the first expandable member, and a first radially expandable stent disposed over both the first expandable member and the auxiliary expandable member. The second delivery catheter has a second shaft, and a second expandable member adjacent the distal end of the second shaft. A portion of the second catheter is disposed under a portion of the first stent, and a portion of the second delivery catheter passes through a side hole in the first stent. The first stent is crimped over the first and second catheters such that the first stent remains attached to the first and the second catheters during advancement of the catheters through a blood vessel.

Abstract: A system for deploying a prosthesis over a Carina between an ipsilateral lumen and a contralateral lumen includes a guidewire, a guidewire capture catheter, a self-expanding tubular prosthesis, and a delivery catheter. The guidewire is first placed in the ipsilateral lumen. The guidewire capture catheter is then advanced from the contralateral lumen to a position at or above the ipsilateral lumen. The guidewire is typically advanced through an occlusion, which may be a total occlusion, and captured by a capture element on the guidewire capture catheter. The guidewire capture catheter pulls the guidewire out through the contralateral side, and the guidewire is used to advance a delivery catheter from the ipsilateral side. The delivery catheter delivers a first segment of the tubular prosthesis in the ipsilateral lumen and a second segment of the prosthesis in the contralateral lumen.

Abstract: A variable flow stent is described for use with AV fistulas, TIPS procedures or dialysis grafts. The flow may be varied by adjusting the diameter of the stent. Embodiments include: a covered stent having a secondary chamber that functions as an air or fluid bladder; an expandable chamber within an interior stent covering; a retractable jack device with hooks that engage (snag) opposing walls of the stent; and, a stent with a hollow chamber or pocket in the interior stent covering into which an expandable balloon can be inserted. A self-healing valve is described for inflating or deflating expandable elements within the stent and may be implemented using a self-healing membrane. A radiopaque collar may be used to provide a marker surrounding the self-healing valve. If under-shunting or over-shunting occurs over time, the variable diameter stent may be adjusted using a second procedure.

Abstract: The techniques of this disclosure generally relate to an assembly including a single multibranch stent device. The single multibranch stent device includes a main body, a proximal coupling extending radially from the main body, and a distal coupling extending radially from the main body. The main body, the proximal coupling, and the distal coupling are permanently coupled to one another and the single multibranch stent device is a single piece. By forming the single multibranch stent device as a single piece, the single multibranch stent device can be deployed in a single deployment thus simplifying the deployment procedure.

Abstract: The present disclosure includes an endoprosthesis delivery system comprising an elongate member, such as a catheter, an endoprosthesis, and an end cap having one or more protrusions extending therefrom. The protrusions may assist in retraction of end cap into an outer sheath, such as an introducer sheath. In some examples, the protrusion includes fins. In some embodiments, the endoprosthesis delivery system further includes a covering member disposed about the endoprosthesis. The protrusions may support the covering member, which may extend beyond the distal end of the endoprosthesis and onto the end cap. In some embodiments, the end cap comprises a tapered profile, which may assist in retraction of the catheter tip and end cap into an outer sheath.

Abstract: A method of producing an arteriovenous (AV) fistula includes producing an anastomosis between a primary blood vessel (e.g., a vein) and a secondary blood vessel (e.g., an artery). A collateral (or competing) blood vessel in fluid communication with one of the primary blood vessel or the secondary blood vessel is identified. A reversible flow restrictor is then applied to the collateral blood vessel to reduce a blood flow rate through the collateral blood vessel. In some embodiments, the anastomosis can be produced percutaneously. In some embodiments, the reversible flow restriction (or a portion thereof) can be removed from the collateral blood vessel. In other embodiments, the reversible flow restriction (or a portion thereof) can be adjusted to allow increased blood flow therethrough while within the collateral blood vessel.

Abstract: Described herein are methods and apparatus for constructing tissue replacements, such as bone replacements that may be used to repair damaged or missing segments of bone, such as may occur in wound repair or as a repair of a congenital anomaly. These methods involve a three-dimensional (3D) cell growth medium made from a yield stress material that allows cells and structures to be easily deposited and positioned.

Abstract: An aortic graft assembly includes a tubular component that defines a wall aperture having a proximal end that extends perpendicular to a major longitudinal axis of the tubular aortic component, and a tunnel graft connected to the wall of the tubular aortic component and extending from the wall aperture toward a proximal end of the tubular aortic component. The aortic graft assembly is delivered to a patient through the wall aperture and into interfering relation with the tunnel graft to treat aortic aneurysms.

Abstract: A prosthetic assembly configured for endovascular placement within an aortic arch and method of use thereof. The prosthetic assembly includes a proximal aortic stent-graft prosthesis configured to be positioned within a proximal portion of the aortic arch adjacent to the brachiocephalic artery, a distal aortic stent-graft prosthesis configured to be positioned within a distal portion of the aortic arch adjacent to the left subclavian artery, a first branch stent-graft prosthesis configured to be positioned within the brachiocephalic artery and a second branch stent-graft prosthesis configured to be positioned in one of the left common carotid and the left subclavian artery. When deployed, a proximal end of the first branch stent-graft prosthesis is disposed within a lumen of the proximal aortic stent-graft prosthesis to proximally displace the ostium of the brachiocephalic artery.

Abstract: Features for a restraint, such as a cap, are described. The restraint secures a cardiac device in a collapsed, delivery configuration for transcatheter delivery to a heart. The restraint may have a tubular sidewall extending from a proximal end to a distal end, a proximal opening defined by the sidewall at the proximal end and a channel defined by the sidewall and extending distally from the proximal opening. The restraint is configured to receive the implant in the collapsed configuration through the proximal opening to radially restrain the implant within the channel. The restraint eliminates the need for a surrounding sheath, reducing the delivery profile and size of the overall delivery system, among other advantages. The restraint may have an atraumatic leading edge to reduce the risk of injury to the patient.

Abstract: A covered stent includes a tubular main stent and a connection stent disposed on the main stent. An opening is formed in a side wall of the main stent. The connection stent includes a fixed segment connected to the side wall of the main stent and a free segment connected to the fixed segment. Each of the fixed segment and the free segment further includes a stent and a coating covering the surface of the stent. One end of the free segment distant from the fixed segment is connected to the edge of the opening, and a gap is formed between one side of the free segment near to the side wall of the main stent and the side wall of the main stent. This stent can effectively resolve the problem of the limitation of an adjusted angle at a connection segment of an external connection stent and has better flexibility.

Abstract: A valved endoprosthesis releasing device and a valved endoprosthesis pertaining to the medicine area, more particularly a device for releasing valved endoprosthesis specifically developed for the combined endovascular treatment of aortic valve disease and ascending aorta segment, said device allowing the assembly to travel endovascularly until the valved endoprosthesis is specifically coupled to repair injured segments of the ascending aorta and replace the calcified aortic valve, besides restoring the anatomy and assuring the consolidation of a suitable blood flow in the region to be treated. The invention comprises a valved endoprosthesis releasing device consisting of several overlapped tubular segments, wherein the movement of the sheath tube releases the valved endoprosthesis coupled to the proximal region for endovascular implantation by expanding the balloon or self-expanding a valved endoprosthesis provided with a tubular body coupled to an aortic valve.

Abstract: Universal endovascular grafts are provided for evaluation and repair of damaged or aneurismal blood vessels. More particularly, the present invention relates to universal fenestrated and universal branched endografts for repair of blood vessels with branches, methods for implanting the endografts in the vessel and for making connection with one or more branches. The universal fenestrated endografts have a body with a first end, a second end, a first wall, a second wall, and an interior passage or lumen. The body further includes openings in communication with the passage at the first and second ends and one or more lateral fenestrations in communication with the lumen. The body further has a necked portion between the ends and a cannulation member. The universal branched endografts have a tubular body with a main lumen and four branch lumens. A large branch extends from the body. The four lumens are positioned about a circumference of the tubular body.

Abstract: The vascular prosthesis includes a luminal graft component that defines at least one fenestration and a crimped adapter at the at least one fenestration. The crimped adapter includes a perimeter and an opening with a diameter smaller than the diameter of the fenestration, and includes a crimped portion of generally concentric folds about the opening. The opening can move relative to the perimeter region of the crimped adapter to accommodate positioning of a branch prosthesis extending through the crimped adaptor. The vascular prosthesis is implanted in a patient to thereby treat, for example, an arterial aneurysm that spans a region of an artery that includes at least one arterial branch.

Abstract: A method for treating a subject includes providing an endovascular system that includes a stent-graft and an elongate delivery shaft assembly. When the delivery shaft assembly is unconstrained and the stent-graft is removably constrained along a distal end portion of the delivery shaft assembly, the delivery shaft assembly is shaped so as to define a self-orienting portion, which is shaped so as to define at least proximal and distal curved portions. The delivery shaft assembly is transvascularly introduced into a descending aorta of the subject and a distal end of the delivery shaft assembly is advanced to an aortic arch, such that the self-orienting portion assumes a desired rotational orientation in the aortic arch. While the distal end of the delivery shaft assembly is positioned in the aortic arch, the stent-graft is released from the distal end portion of the delivery shaft assembly. Other embodiments are also described.

Abstract: A deployment apparatus and method for deploying one or more stents to a bifurcated vessel is provided. The invention is particularly suited for T-type bifurcated vessels where a side branch extends from a main branch. The deployment apparatus has a primary inflatable portion for engagement within the main branch and a secondary inflatable portion for engagement within the side branch. A main stent is arranged on the primary inflatable portion and radially expanded within the main branch while the secondary inflatable portion maintains registration with the side branch. A side branch stent is then arranged on the secondary inflatable portion and expanded within the side branch while the primary inflatable portion maintains registration with the expanded main stent. A bifurcated stent system suitable for bifurcated lesions is also provided comprising a side branch stent with a shaped end designed to engage a similarly shaped side opening in a main stent.

Abstract: An arteriovenous graft and methods of reducing the risk of graft thrombosis and extending patency of the arteriovenous graft are provided herein. The arteriovenous graft is operable for attaching to a vein at a venous anastomosis. In some aspects, the arteriovenous graft includes a plurality of grooves at a venous anastomosis end of the arteriovenous graft and the venous anastomoses may be arranged such that the arteriovenous graft and the vein meet at an angle of 30° or less.

Abstract: In one embodiment according to the present invention, a stent is described having a generally cylindrical body formed from a single woven nitinol wire. The distal and proximal ends of the stent include a plurality of loops, some of which include marker members used for visualizing the position of the stent. In another embodiment, the previously described stent includes an inner flow diverting layer.

Abstract: A transcatheter valve assembly replacement device includes an improved paravalvular seal.

Abstract: A delivery system for delivering and deploying stents with proximal and distal apices includes a guidewire catheter, a nose cone assembly, a proximal capture portion and a stent graft with proximal and distal stents. The nose cone assembly is at the distal end of the guidewire catheter and includes a nose cone and a distal capture portion. The proximal capture portion is proximal to the distal capture portion of the nose cone assembly. The proximal stent is releasably secured to the distal capture portion and the distal stent is releasably secured to the proximal capture portion. The stent graft can be deployed by releasing the proximal stent and the distal stent from proximal and distal capture portions of the delivery system.

Abstract: A medical device is provided in which one or both ends of the device encourage the formation of tissue across substantially the entire area of the respective end that is exposed to the blood flow for reducing the risk of a thrombotic embolism. The medical device further includes stabilizing wires configured to engage tissue at a target site when the medical device is in an expanded configuration and to at least partially retract into the medical device when the medical device is in a collapsed configuration.

Abstract: An implantable device includes an outer tubular member defining a longitudinal axis and a lumen. The outer tubular member includes: an outer wall portion having a plurality of first strands defining a plurality of first openings therebetween, the outer wall portion having a first porosity; and an inner baffle portion disposed within the lumen, the inner baffle portion including a plurality of second strands defining a plurality of second openings therebetween, the inner baffle portion having a second porosity that is lower than the first porosity of the outer wall portion.

Abstract: A suture to be used in producing a medical instrument provided with a sutured site such as a stent graft, an artificial blood vessel or an artificial heart valve, has two components, i.e., a high melting-point component and a low-melting point component, the difference between the melting points of components being 30° C. or more and the low-melting point component is exposed on the suture surface entirely along the length direction. When a medical material formed of a fabric or a film is sutured or knotted with the suture and then the suture site is heated at such a temperature not allowing the high-melting point component but the low-melting point component alone to melt, the sutured site is fused and fixed. Thus, a knot or a seam, which sustains the fiber shape and strength and never becomes loose, can be formed.

Abstract: Described herein are methods and apparatus for constructing tissue replacements, such as bone replacements that may be used to repair damaged or missing segments of bone, such as may occur in wound repair or as a repair of a congenital anomaly. These methods involve a three-dimensional (3D) cell growth medium made from a yield stress material that allows cells and structures to be easily deposited and positioned.

Abstract: An occlusive implant for bifurcation aneurysms (A), with the implant (1) being in an expanded state in which it is implanted in the blood vessel and in a contracted state in which it is movable through the blood vessel, with the implant (1) having a proximal fixing section (3) by means of which the implant (1) can be secured to the wall of a blood vessel, a distal section (5) where the implant (1) in expanded state is radially widened relative to the fixing section (3) and which is intended for placement in or in front of the aneurysm (A), and having a transition section (4) located between the fixing section (3) and the distal section (5), wherein fixing section (3) is attached to an delivery wire (2) in a detachable manner and wherein the transition section (4) has a second detachment point (7) which enables the distal section (5) to be detached.

Abstract: An endoluminal prosthesis system for being deployed in a patient's aorta near the heart includes a graft having a tubular body with a lumen extending from proximal end configured to be deployed near a patient's heart to a distal end configured to be deployed away from the patient's heart. A collar around the graft is sized and configured to be sutured to a patient's aorta. Passageways in the middle portion of the graft permit fluid communication from the lumen of the graft to an exterior of the graft. A respective bridging branch is disposed at each of the passageways, each of the bridging branches having an inner opening and an outer opening so that the bridging branches provide fluid communication from the lumen of the graft to the exterior of the graft. A respective bridging graft is sized and arranged to mate with each of the bridging branches.

Abstract: A spiral-based thin-film mesh for medical devices and related methods is provided. The spiral-based thin-film mesh may be used as a stent cover for a stent device. The thin-film mesh may include a plurality of spirals. The spirals allow the thin-film mesh to expand omni-directionally. In one or more embodiments, the spirals may be logarithmic spirals, golden spirals, approximated golden spirals, box Phi spirals, or Fibonacci spirals. The thin-film mesh may be formed from thin-film Nitinol (TFN), and may be fabricated via sputter deposition on a micropattemed wafer.

Abstract: A transcatheter valve assembly replacement device includes a paravalvular seal that includes outwardly extending fibers that create a seal with the annulus when the valve assembly is deployed. An inwardly extending seal is attached to an outer frame. The inwardly extending seal is engaged with prosthetic valve leaflets.

Abstract: The abstract has been amended to the following: “A heart valve replacement device for endovascular repair is provided. The heart valve replacement device includes a plurality of fibers for creating a seal with an anatomy of the patient. A heart valve carried by an inner graft covering. The plurality of fibers form an outer seal for preventing paravalvular leaks between the replacement heart valve and the native valve of a patient.

Abstract: The techniques of this disclosure generally relate to a modular stent device that is deployed via supra aortic access through the brachiocephalic artery. The modular stent device is a base or anchor component to which additional modular stent devices can be attached to exclude diseased areas of the aorta while at the same time allowing perfusion of the left common carotid artery and the left subclavian artery.

Abstract: The techniques of this disclosure generally relate to an assembly including a single multibranch stent device. The single multibranch stent device includes a main body, a proximal coupling extending radially from the main body, and a distal coupling extending radially from the main body. The main body, the proximal coupling, and the distal coupling are permanently coupled to one another and the single multibranch stent device is a single piece. By forming the single multibranch stent device as a single piece, the single multibranch stent device can be deployed in a single deployment thus simplifying the deployment procedure.

Abstract: Medical procedures and devices suitable for reducing the risk of embolic cerebrovascular events, including but not limited to cardioembolic stroke, that result from emboli entering the right or left common carotid artery. The invention uses a combination of intracranial flow diverting stent technologies and carotid stent technologies to achieve clinical objectives of embolic stroke prevention without thromboembolic and/or vascular stenosis complication. Such a stent has struts that generate high radial forces for endothelial apposition, and a mesh with interstices sufficiently small to prevent clinically significant-sized embolic material from passing therethrough from the common carotid artery into the internal carotid artery, but sufficiently large to enable blood and small clinically insignificant-sized embolic material to pass therethrough from the common carotid artery into the internal carotid artery.

Abstract: The present application discloses a stent-graft prosthesis and a method for navigating such stent-graft prosthesis e.g. to a branch vessel. A first stent-graft prosthesis may include a main body and at least one lateral side branch connected to the main body. A further stent-graft prosthesis according to examples has a body having a generally tubular wall structure, the wall structure of the further stent-graft prosthesis including an orifice element for receiving a guiding element. Preferably the wall structure has an overlap region for interconnection, e.g. to the first stent-graft prosthesis. The orifice element is then arranged at said overlap region, wherein said overlap region is preferably arranged at a proximal end region of said body. The guiding element preferably is a textile thread or suture thread, optionally with a radiopaque marker, such as a fiducial marker and/or a radiopaque elongate marker extending at least along a portion of a length of said guiding element.

Abstract: An endovascularly deployed prosthetic includes a portion for being positioned within an ascending aorta. The prosthesis includes a replacement aortic valve on a proximal end thereof. The prosthesis includes an increased diameter portion that seals against the aorta at a more distal portion, and a pair of conduits extend from the increased diameter portion to the coronaries for fluidly coupling the coronaries to the prosthesis.

Abstract: A double-layer blood vessel stent. A skirt-sided stent is provided on a main body stent. A first developing member and a second developing member are provided on the main body stent. The first developing member includes a first developing portion and a second developing portion, where the first developing portion and the second developing portion are flush with a free end at a position where the distance between the intersections on a plane perpendicular to the direction of an axis of the main body stent is the minimum distance; and an end, away from a first end, of the second developing member is flush with an end away from a tapered section of an extending section. This structure allows for accurate positioning of the double-layer vessel stent.

Abstract: A transcatheter aortic valve replacement (TAVR) device includes a paravalvular seal that includes outwardly extending fibers that create a seal with the aortic annulus when the TAVR is deployed.

Abstract: An endovascular stent-graft is provided that includes a flexible stent member and a tubular fluid flow guide. The tubular fluid flow guide includes first and second fabrics. The first fabric includes a first biologically-compatible substantially blood-impervious material, and is attached to and covers the stent member along a first longitudinal portion of the stent-graft. The second fabric includes a second biologically-compatible substantially blood-impervious material different from the first material, and is attached to and covers the stent member along a second longitudinal portion of the stent-graft. The second longitudinal portion is at least partially non-longitudinally-overlapping with the first longitudinal portion. Other embodiments are also described.

Abstract: A prosthetic assembly for repairing a target tissue defect within a target vessel region configured includes an exclusion structure sized to substantially bypass target tissue defect, and includes a branch assembly. The branch assembly can include a self-expanding outer branch prosthesis having an inflow region configured to deform to a non-circular cross-sectional-shape when deployed, and a support structure at least partially disposed within the inflow region. The support structure preserves blood flow to the branch vessel while the deformed inflow region inhibits blood leakage between and/or around the prosthetic assembly.

Abstract: This prosthesis (1), comprises an expandable tubular frame (2) with a mesh structure and a prosthetic valve (3) mounted on this frame; the ventricular portion (2v) of the frame (2) has a large indentation (6) on one side, extending lengthwise from the end of this ventricular portion (2v) that is opposite said annular portion (2i) to the part of this ventricular portion (2v) close to the annular portion (2i), this indentation (6) extending over a sector of the circumference of the prosthesis (1) of about 90 to 140°; said atrial portion (2a) flares toward the outside of the prosthesis, from said annular portion (2i) toward the end of this atrial portion opposite this annular portion, and comprises anchoring spikes (5a) on the side of said annular portion (2i); and said ventricular portion (2v) has a substantially spherical or ovoid shape and comprises anchoring spikes (5v) on the side of said annular portion (2i).

Abstract: The present embodiments describe a multi-component endograft having a first endograft with first and second wall openings, a second endograft with a third wall opening, a third endograft with a fourth wall opening, where during an adjustment state the second and third endografts are independently adjustable, both vertically along a longitudinal axis and rotationally relative to the longitudinal axis, (1) while keeping the perimeter of the third wall opening primarily encompassed by the perimeter of the first wall opening and (2) while keeping the perimeter of the fourth wall opening primarily encompassed by the perimeter of the second wall opening.

Abstract: An external vascular support for shaping a vein-artery junction between an artery and a vein anastomosed to the artery, the support comprising: an arterial portion that is shaped to be in apposition with an exterior wall of the artery when the artery is accommodated within a lumen of the arterial portion, and a venous portion that is shaped to be in apposition with an exterior wall of the vein when the vein is accommodated within a lumen of the venous portion, wherein the arterial and venous portions are physically connected at an acute angle, and the corner of the acute angle is shaped as a rounding having a radius of curvature in the range of 0.25 mm to 4 mm.

Abstract: An endovascularly deployed prosthetic includes a portion for being positioned within an ascending aorta. The prosthesis includes a replacement aortic valve on a proximal end thereof. The prosthesis includes an increased diameter portion that seals against the aorta at a more distal portion, and a pair of conduits extend from the increased diameter portion to the coronaries for fluidly coupling the coronaries to the prosthesis.

Abstract: An intraluminal vascular prosthesis assembly, having a hollow cylindrical body with a first end and a second end is provided. The assembly includes, at its first end, a first vascular prosthesis portion, and at its second end, a second vascular prosthesis portion which has only a prosthesis material. The vascular prosthesis assembly has a stent portion which is provided between the first vascular prosthesis portion and the second vascular prosthesis portion, the stent portion being free of prosthesis material to allow fluid flow there through and received within the aortic arch and spanning the brachiocephalic artery, left common carotid artery, and left subclavian artery when placed within the aortic arch of a patient.