Fiber Patents (Class 623/1.54)
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Patent number: 9867690Abstract: A system for applying a fiber matrix on a tubular member is provided. A mandrel, configured for atraumatic placement within the tubular member, is included. Methods for atraumatic placement of a mandrel into a tubular member are also provided.Type: GrantFiled: February 8, 2012Date of Patent: January 16, 2018Assignee: NEOGRAFT TECHNOLOGIES, INC.Inventors: Lorenzo Soletti, Mohammed S. El-Kurdi, Jon McGrath, J. Christopher Flaherty, Liem Vu, Jerry Brightbill, Stephen Evans, Joseph Ting, David Rezac, Timothy Robinson
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Patent number: 9526639Abstract: A stent, for example, is provided with a plurality of frame elements, which may have an undulating form. The stent is provided with a plurality of magnetic elements between adjacent stent elements. The magnetic elements on opposing circumferentially facing portions or sides of the strut elements have the same polarities so as to produce repulsive forces biasing the stent structure into a radially expanded configuration. The magnetic elements provide an alternative opening force on the stent, enabling the stent to be made of struts of thinner and weaker material or of a non-sprung material. The magnetic elements also provide a constant opening force in order to retain the stent reliably in position within a vessel. The stent could be made of a biodegradable material.Type: GrantFiled: May 11, 2015Date of Patent: December 27, 2016Assignee: COOK MEDICAL TECHNOLOGIES LLCInventors: Palle M. Hansen, Torben P. Andersen
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Patent number: 8992594Abstract: A tubular graft device is provided comprising a tubular member and a fiber matrix of one or more polymers about a circumference of the tubular member. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a harvested saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft and connecting the graft between a first body space and a second body space, such as the aorta and a location on an occluded coronary artery, distal to the occlusion.Type: GrantFiled: December 16, 2010Date of Patent: March 31, 2015Assignee: Neograft Technologies, Inc.Inventors: Lorenzo Soletti, Mohammed S. El-Kurdi, Jon McGrath, J. Christopher Flaherty
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Publication number: 20150086607Abstract: A synthetic construct suitable for implantation into a biological organism that includes at least one polymer scaffold; wherein the at least one polymer scaffold includes at least one layer of polymer fibers that have been deposited by electrospinning; wherein the orientation of the fibers in the at least one polymer scaffold relative to one another is generally parallel, random, or both; and wherein the at least one polymer scaffold has been adapted to function as at least one of a substantially two-dimensional implantable structure and a substantially three-dimensional implantable tubular structure.Type: ApplicationFiled: September 25, 2014Publication date: March 26, 2015Inventors: Jed K. JOHNSON, Ross KAYUHA
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Patent number: 8986393Abstract: A radiation and radiochemically sterilized, multi-component, fiber-reinforced composite, absorbable/disintegratable urinogenital stent, such as an endoureteral stent, with radiomodulated residence time in the biological site of 1 to 10 weeks depending on the high energy radiation dose used for sterilization.Type: GrantFiled: November 22, 2011Date of Patent: March 24, 2015Assignee: Poly-Med, Inc.Inventors: Shalaby W. Shalaby, Kenneth W. Clinkscales, Kenneth D. Gray
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Patent number: 8940041Abstract: The disclosure relates to a woven fabric for use in an implantable medical device. The woven fabric has shape memory element strands woven with textile strands. At least one of the shape memory element strands has at least one float of at least five textile strands between binding points.Type: GrantFiled: April 23, 2012Date of Patent: January 27, 2015Assignee: Cook Medical Technologies LLCInventors: James M. Carlson, Shyam S.V. Kuppurathanam, Fred T. Parker, Rebecca Sue Todd
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Patent number: 8741201Abstract: Polymeric composite stents reinforced with fibers for implantation into a bodily lumen are disclosed.Type: GrantFiled: September 9, 2010Date of Patent: June 3, 2014Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Bin Huang, David C. Gale
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Patent number: 8733274Abstract: Inkjet print head dies are directly seated upon an exterior of a tubular member so as to face different directions.Type: GrantFiled: October 20, 2006Date of Patent: May 27, 2014Assignee: Hewlett-Packard Development Company, L.P.Inventors: David R. Otis, Jr., Jeffrey A. Nielsen, Casey T. Miller, Gerald F. Meehan, Isaac Farr, Joseph W. Dody
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Publication number: 20140074225Abstract: A medical appliance or prosthesis may comprise one or more layers of rotational spun nanofibers, including rotational spun polymers. The rotational spun material may comprise layers including layers of polytetrafluoroethylene (PTFE). Rotational spun nanofiber mats of certain porosities may permit tissue ingrowth into or attachment to the prosthesis. Additionally, one or more cuffs may be configured to allow tissue ingrowth to anchor the prosthesis.Type: ApplicationFiled: November 15, 2013Publication date: March 13, 2014Applicant: Merit Medical Systems, Inc.Inventors: John William Hall, Zeke Eller, Robert S. Kellar, Rachel Lynn Simmons, Bart Dolmatch, Wayne Mower, Robert J. Radford
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Publication number: 20130211497Abstract: The present embodiments provide an endoluminal prosthesis, such as a stent-graft, having a relatively low delivery profile. In one embodiment, the prosthesis comprises a membrane, and at least one stent having contracted and expanded states, where the stent is coupled to the membrane and maintains patency in the expanded state. The prosthesis further may comprise selectively oriented axial and/or circumferential fibers arranged at predetermined locations along the length and circumference of the prosthesis. An increased population density of the circumferential and/or axial fibers may be provided in areas in which the at least one stent portion is attached to the membrane, or in areas of higher physiological loads imposed upon the endoluminal prosthesis.Type: ApplicationFiled: August 10, 2010Publication date: August 15, 2013Applicant: COOK MEDICAL TECHNOLOGIES LLCInventors: Steven J. Charlebois, William Kurt Dierking, Matthew S. Huser, Keith Milner, Jichao Sun
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Publication number: 20130184810Abstract: A medical appliance or prosthesis may comprise one or more layers of rotational spun nanofibers, including rotational spun polymers. The rotational spun material may comprise layers including layers of polytetrafluoroethylene (PTFE). Rotational spun nanofiber mats of certain porosities may permit tissue ingrowth into or attachment to the prosthesis. Additionally, one or more cuffs may be configured to allow tissue ingrowth to anchor the prosthesis.Type: ApplicationFiled: January 15, 2013Publication date: July 18, 2013Applicant: Merit Medical Systems, Inc.Inventor: Merit Medical Systems, Inc.
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Publication number: 20130184808Abstract: A medical appliance or prosthesis may comprise one or more layers of rotational spun nanofibers, including rotational spun polymers. The rotational spun material may comprise layers including layers of polytetrafluoroethylene (PTFE). Rotational spun nanofiber mats of certain porosities may permit tissue ingrowth into or attachment to the prosthesis. Additionally, one or more cuffs may be configured to allow tissue ingrowth to anchor the prosthesis.Type: ApplicationFiled: January 15, 2013Publication date: July 18, 2013Applicant: MERIT MEDICAL SYSTEMS, INC.Inventor: MERIT MEDICAL SYSTEMS, INC.
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Patent number: 8419788Abstract: A woven, self-expanding stent device has one or more strands and is configured for insertion into an anatomical structure. The device includes a coupling structure secured to two different strand end portions that are substantially aligned with each other. The two different strand end portions include nickel and titanium. The coupling structure is not a strand of the device.Type: GrantFiled: July 13, 2012Date of Patent: April 16, 2013Assignee: IDev Technologies, Inc.Inventors: Jeffery Sheldon, Richard Booth, Ken Bueche
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Patent number: 8388679Abstract: A prosthetic aortic conduit for replacing a root portion of an aorta is provided. The conduit comprises a continuous tubular conduit along a substantially common axis. A portion of the tubular conduit does not substantially deform in a longitudinal direction and has resilient means which allow said another portion of the conduit to be expandable in a lateral direction. The portion that is able to deform laterally mimics the function of the sinuses of Valsalva. The method of manufacturing such a conduit comprises the steps of having a continuous weave of rows of yarn or the equivalent with a change in tightness of the rows so that in some portion of the conduit it is expandable in the lateral direction and in some portion of the conduit it is expandable in the longitudinal direction.Type: GrantFiled: June 8, 2010Date of Patent: March 5, 2013Assignee: Maquet Cardiovascular LLCInventor: George Du
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Patent number: 8367148Abstract: Methods for making collagen based biocomposite constructs and related devices include: (a) winding at least one collagen fiber a number of revolutions about a length of a support member having a long axis, the winding having at least one defined pitch and/or fiber angle relative to the long axis of the support member to form an elongate construct; and (b) applying a fluid polymeric material, such as, for example, an acrylate emulsion and/or other thermoplastic material, onto the collagen fiber during the winding step. Optionally, the fluid polymeric material can include antibiotics and/or other therapeutic agents for additional function/utility.Type: GrantFiled: October 9, 2009Date of Patent: February 5, 2013Assignee: MiMedx Group, Inc.Inventors: Kerriann Greenhalgh, Mengyan Li, Thomas J. Koob
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Patent number: 8343568Abstract: A stent fixture for supporting a stent during formation of a coating is provided.Type: GrantFiled: September 24, 2010Date of Patent: January 1, 2013Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Yung-Ming Chen, Allan Bradshaw, Philip C. Foreman, Greg Teaby
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Patent number: 8252064Abstract: Absorbable/disintegratable endourological stents, specifically endoureteral stents, and applicators for their introduction into the biological site, are formed from fiber-reinforced elastomeric films configured to prevent their migration from the application site.Type: GrantFiled: February 2, 2006Date of Patent: August 28, 2012Assignee: Poly-Med, Inc.Inventors: Shalaby W. Shalaby, Kenneth W. Clinkscales
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Patent number: 8197537Abstract: The present invention provides an implantable prosthesis and more specifically, an implantable tubular textile prosthesis comprising a biocompatible fabric having inner and outer surfaces and first and second ends; the fabric having a textile construction comprising cold drawn PTFE yarns having a substantially uniform denier and high molecular orientation. Use of cold drawn PTFE yarns result in implantable prostheses that have excellent abrasion resistance, strength and lubricity properties. Useful textile constructions include weaves, knits, braids, filament windings, spun windings and combinations thereof. The prostheses of the present invention are lubricious and have characteristics that closely resemble the properties of a natural body lumen.Type: GrantFiled: August 4, 2006Date of Patent: June 12, 2012Assignee: Boston Scientific Scimed, Inc.Inventors: Wesley I. Edens, Charles B. Hebert
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Patent number: 8083805Abstract: This invention deals with an absorbable/disintegratable endo-urological stent and applicators for introduction into biological conduits, including such as urethras and ureters, with said stent comprising a fiber-reinforced, multicomponent tube made of polyesters having a range of physicochemical properties.Type: GrantFiled: August 16, 2005Date of Patent: December 27, 2011Assignee: Poly-Med, Inc.Inventor: Shalaby W. Shalaby
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Patent number: 8083806Abstract: A radiation and radiochemically sterilized, multi-component, fiber-reinforced composite, absorbable/disintegratable urinogenital stent, such as an endoureteral stent, with radiomodulated residence time in the biological site of 1 to 10 weeks depending on the high energy radiation dose used for sterilization.Type: GrantFiled: February 12, 2009Date of Patent: December 27, 2011Assignee: Poly-Med, Inc.Inventors: Shalaby W Shalaby, Kenneth W Clinkscales, Kenneth David Gray
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Patent number: 7993391Abstract: Medical devices, for example, implantable devices such as endoprostheses, include a composite material having a polymer.Type: GrantFiled: January 5, 2006Date of Patent: August 9, 2011Assignee: Boston Scientific SciMed, Inc.Inventor: Jonathan S. Stinson
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Patent number: 7993383Abstract: A stent assembly (42) adapted for endoluminal placement by endovascular deployment for the treatment of a false lumen (10) associated with a vascular dissection. The stent assembly has a number of self expanding stents (35) connected together to define an elongate substantially cylindrical lumen wall engaging surface. The stents are adapted to provided pressure on the wall of the lumen adjacent to and extending away from a rupture. A deployment device (40) for the stent assembly includes a sheath (48) and a retention and release arrangement (50) to retain the proximal end (37) of the stent graft to the deployment device. Release of the stent assembly is by withdrawal of the sheath before release of its proximal end by the use of a trigger wire (54) of the retention and release arrangement.Type: GrantFiled: September 28, 2005Date of Patent: August 9, 2011Assignees: William A. Cook Australia Pty. Ltd., Cook Medical Technologies lLCInventors: David Ernest Hartley, Erik E. Rasmussen, Thomas C. McIntyre
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Publication number: 20100324646Abstract: A system for treating a vascular condition includes a stent including hydroxyapatite fibers interwoven to define a stent lumen. Another aspect of the invention is a method of manufacturing a stent by forming hydroxyapatite fibers and biodegradable polymeric fibers, and interweaving the fibers to form a stent wall. The hydroxyapatite fibers can be formed by a sol-gel process, followed by spinning of the gel to form the hydroxyapatite fibers.Type: ApplicationFiled: June 18, 2009Publication date: December 23, 2010Applicant: Medtronic Vascular, Inc.Inventor: Iskender Bilge
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Publication number: 20100268331Abstract: The invention relates to a gel-spinning process for producing a high tensile strength ultra high molecular weight polyethylene (UHMWPE) multifilament yarn comprising ultra-low dtex filaments, the process being characterized in that the draw ratio DRfluid applied to fluid filaments obtained by spinning a solution of UHMWPE through a spinneret and into an air gap, is at least 450, wherein DRfluid=DRsp*DRag, the DRsp and DRag being the draw ratios in the spinholes and in the air gap, respectively; and provided that DRag is at least 30. The UHMWPE multifilament yarns produced thereof were characterized by a tensile strength of at least 3.5 GPa and contained filaments having a dtex of at most 0.5. The invention further relates to products comprising said yarns, e.g. fabrics, medical devices and composite and ballistic articles.Type: ApplicationFiled: December 17, 2008Publication date: October 21, 2010Inventors: Joseph Arnold Paul Maria J.A.P.M Simmelink, Roelof Marissen
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Patent number: 7815763Abstract: The present invention involves porous polymer membranes, suitable for use in medical implants, having controlled pore sizes, pore densities and mechanical properties. Methods of manufacturing such porous membranes are described in which a continuous fiber of polymer is extruded through a reciprocating extrusion head and deposited onto a substrate in a predetermined pattern. When cured, the polymeric material forms a stable, porous membrane suitable for a variety of applications, including reducing emboli release during and after stent delivery, and providing a source for release of bioactive substances to a vessel or organ and surrounding tissue.Type: GrantFiled: December 19, 2005Date of Patent: October 19, 2010Assignee: Abbott Laboratories Vascular Enterprises LimitedInventors: Joost J. Fierens, Erhard Huesler, Arik Zucker, Eric Marcoux, Philippe Nicaise, Sebastien Dubois
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Patent number: 7785363Abstract: The ePTFE structure includes an ePTFE tubular structure having opposite ends and a longitudinal axis. The ePTFE tubular structure is formed from rotating the opposite ends relative to one another in a direction of rotation about the longitudinal axis. The ePTFE tubular structure has a node and fibril micro-structure in which substantially all of the fibrils are oriented in the direction of rotation.Type: GrantFiled: August 15, 2007Date of Patent: August 31, 2010Assignee: Boston Scientific Scimed, Inc.Inventors: Julio Duran, Krzysztof Sowinski, Jamie S. Henderson
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Patent number: 7722578Abstract: Medical devices and related methods are disclosed.Type: GrantFiled: September 8, 2004Date of Patent: May 25, 2010Assignee: Boston Scientific Scimed, Inc.Inventors: Michael S. Arney, Scott R. Schewe
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Patent number: 7722914Abstract: Pharmacologically active, easy-to-deploy, biomechanically compatible, inflatable endovascular, drug-eluting stent are formed of a primary expandable polymeric or metallic construct, intimately mantled with a biomechanically compatible, polymeric microporous, microfibrous, compliant, stretchable fabric formed by direct electrospinning onto the outside surface of the primary construct using at least one polymer solution containing at least one active compound, selected from those expected to control key biological events leading to in-stent restenosis.Type: GrantFiled: May 14, 2008Date of Patent: May 25, 2010Assignee: Poly-Med, IncInventor: Shalaby W. Shalaby
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Patent number: 7666496Abstract: The ePTFE structure includes an ePTFE structure which has a node and fibril micro-structure. The micro-structure includes specific nodes which are connected to the fibrils. One or more of the specific nodes are sintered and the fibrils are un-sintered. A method for making the ePTFE structure includes identifying and sintering one or more of the specific nodes.Type: GrantFiled: May 24, 2006Date of Patent: February 23, 2010Assignee: Boston Scientific Scimed, Inc.Inventor: Julio Duran
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Patent number: 7659219Abstract: The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting proportionally increased mechanical strength in one or more directions. The web materials often possess a high degree of loft. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof. The web materials possess haemostatic properties.Type: GrantFiled: January 30, 2006Date of Patent: February 9, 2010Assignee: Gore Enterprise Holdings, Inc.Inventors: Roy Biran, Edward H. Cully, Ted R. Farnsworth, Charles Flynn, Philip P. Off, Charles F. White
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Patent number: 7655584Abstract: The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a very high degree of porosity. The web materials are very supple and soft, while exhibiting proportionally increased mechanical strength in one or more directions. The web materials often possess a high degree of loft. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof. In some embodiments, the web materials exhibit significant thrombogenic properties.Type: GrantFiled: July 29, 2005Date of Patent: February 2, 2010Assignee: Gore Enterprise Holdings, Inc.Inventors: Roy Biran, Edward H. Cully, Ted R. Farnsworth, Charles Flynn, Charles F. White
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Patent number: 7651522Abstract: The invention relates to a medicinal implant or instrument, more particularly to a vascular endoprosthesis (1), having a radially dilatable hose part (2) comprised of a tubular knitted fabric of interdigitating meshes composed of one or more individual fibres (9). To provide such an implant or instrument that allows for MR-imaging of the interior of the implant or instrument, the invention proposes that the fibres (9) of the knitted fabric be electrically conductive and form an inductor (7, 8) within a high-frequency resonant circuit.Type: GrantFiled: October 2, 2006Date of Patent: January 26, 2010Inventors: Martin Busch, Dietrich H. W. Grönemeyer
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Publication number: 20090048658Abstract: The ePTFE structure includes an ePTFE tubular structure having opposite ends and a longitudinal axis. The ePTFE tubular structure is formed from rotating the opposite ends relative to one another in a direction of rotation about the longitudinal axis. The ePTFE tubular structure has a node and fibril micro-structure in which substantially all of the fibrils are oriented in the direction of rotation.Type: ApplicationFiled: August 15, 2007Publication date: February 19, 2009Inventors: Julio Duran, Krzysztof Sowinski, Jamie S. Henderson
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Publication number: 20080306585Abstract: A thread for forming a vascular stent implanted in vessels is provided. This thread is formed by melt-spinning a biodegradable polymer. On the surface of the thread, there is formed a layer of a drug-containing biodegradable polymer of the same sort as the biodegradable polymer constituting the thread.Type: ApplicationFiled: March 20, 2008Publication date: December 11, 2008Applicant: KABUSHIKIKAISHA IGAKI IRYO SEKKEIInventor: Igaki Keiji
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Patent number: 7413575Abstract: The present invention provides a bioactive, small-diameter (typically less than 6 mm in internal diameter) vascular graft prosthesis, and is a textile conduit preferably manufactured using a novel electrospinning perfusion methodology. One preferred embodiment is a nanofibrous biocomposite textile conduit which comprises a prepared liquid admixture of polyester (Dacron), a biodurable implantable synthetic polymer, and Type IV collagen, an extracellular matrix protein. This prepared admixture and blending of diverse fibrous matter is utilized in a novel electrospinning perfusion process to form a small-diameter (less than 6 mm) fabricated textile conduit, a discrete article of manufacture, which then serves as an antecedent tangible workpiece for a subsequently-made prosthetic vascular graft construct.Type: GrantFiled: August 25, 2005Date of Patent: August 19, 2008Inventors: Matthew D. Phaneuf, Philip J. Brown, Martin J. Bide
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Publication number: 20080154357Abstract: A vascular prosthesis, comprising a primary tubular structure of non-woven polymer fibers and a secondary tubular structure of non-woven polymer fibers, the primary and the secondary tubular structures being in fluid communication via an anastomosis such that the primary tubular structure terminates at the anastomosis and the secondary tubular structure continues at the anastomosis.Type: ApplicationFiled: January 25, 2006Publication date: June 26, 2008Applicant: Nicast Ltd.Inventor: Alon Shalev
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Publication number: 20080058916Abstract: A method of manufacturing a radially expandable an implantable medical device, the method comprising: providing a plurality of fibers, the fibers comprising a polymer; disposing the plurality of fibers on a cylindrical support element to form a tubular structure, the tubular structure having an initial diameter; heat setting the tubular structure such that the temperature of the tubular structure is between Tg to Tm of the polymer while heat setting, wherein the tubular structure is maintained at a heat set diameter which is equal to or substantially equal to the initial diameter; and fabricating an implantable medical device from the tubular structure.Type: ApplicationFiled: May 31, 2006Publication date: March 6, 2008Inventors: Bin Huang, David C. Gale
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Patent number: 7318838Abstract: The smart textile vascular graft is used with an electrical control unit. The vascular graft includes a tube structure formed of a textile material. At least one active fiber is incorporated in the textile material. The active fiber provides electrical coupling thereof to the electrical control unit to provide for transmission of a control signal between the active fiber and control unit. The active fiber has at least one physical characteristic which is variable and corresponds to the control signal to provide communication between the active fiber and electrical control unit relating to the physical characteristic.Type: GrantFiled: December 31, 2004Date of Patent: January 15, 2008Assignee: Boston Scientific Scimed, Inc.Inventor: Jamie Henderson
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Publication number: 20040098110Abstract: Novel endoprostheses comprising one or more photocurable materials are disclosed. Said endoprostheses may comprise regions wherein said photocurable materials are selectively disposed about said endoprosthesis and are cured according to desired parameters to achieve varying desired properties. Said properties may include but are not limited to cross-linking density, material density, modulus of elasticity, rate of erosion, extensibility, compressibility, mechanical strength, tensile strength, crystallinity, diffusion coefficient, and permeability.Type: ApplicationFiled: January 15, 2003Publication date: May 20, 2004Inventors: Michael S. Williams, Kevin D. Holbrook, Richard A. Glenn, Jeffrey A. Smith, Joseph M. DeSimone
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Publication number: 20040024442Abstract: This invention relates to an elastomerically recoverable PTFE material that includes a longitudinally compressed fibrils of ePTFE material penetrated by elastomeric material within the pores defining the elastomeric matrix. The elastomeric matrix and the compressed fibrils cooperatively expand and recover without plastic deformation of the ePTFE material. This invention was used for various prosthesis, such as a vascular prosthesis like a patch, a graft and an implantable tubular stents. Furthermore, this invention discloses a method of producing the elastomerically recoverable PTFE material which include the steps of: providing the specified ePTFE, defined by the nodes and fibrils, to meet the desired end use; longitudinally compressing the fibrils of the ePTFE, the pore size sufficiently enough to permit penetration of the elastomeric material; applying the elastomeric material within the pores to provide a structurally integral elastomerically recoverable PTFE material defining an elastomeric matrix.Type: ApplicationFiled: June 25, 2002Publication date: February 5, 2004Applicant: SCIMED Life Systems, Inc.Inventors: Krzysztof Sowinski, Ronald Rakos
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Patent number: 6663667Abstract: A woven vascular graft having a texturized outer surface to promote tissue ingrowth into the graft. The outer surface of the graft is equipped with a plurality of threads that are woven into, and extend from, the outer surface. The threads may be arranged in rows, lines or a geometric pattern. Alternatively, the threads may be towel-like. Such towel-like threads may be arranged in the form of a cuff at each end of the graft, or may cover larger portions of the exterior of the graft. The graft may be equipped with only one texture, or with a plurality of different textures.Type: GrantFiled: October 31, 2001Date of Patent: December 16, 2003Assignee: Edwards Lifesciences CorporationInventors: Mark Dehdashtian, Jens Allenberg
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Patent number: 6605294Abstract: Pharmaceutically acceptable hydrogel polymers of natural, recombinant or synthetic origin, or hybrids thereof, are introduced in a dry, less hydrated, or substantially deswollen state and rehydrate in a physiological environment to undergo a volumetric expansion and to affect sealing, plugging, or augmentation of tissue, defects in tissue, or of organs. The hydrogel polymers may deliver therapeutic entities by controlled release at the site. Methods to form useful devices from such polymers, and to implant the devices are provided.Type: GrantFiled: August 14, 1998Date of Patent: August 12, 2003Assignee: Incept LLCInventor: Amarpreet S. Sawhney
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Publication number: 20030097174Abstract: A prosthesis, and method for forming same, are provided which includes expanded polytetrafluoroethylene (ePTFE) tubes having angularly offset node and fibril configurations. Also, the node and fibril configurations are angularly offset from the longitudinal axes of the respective tubes, providing resistance against failure in the longitudinal direction.Type: ApplicationFiled: November 21, 2001Publication date: May 22, 2003Applicant: Scimed Life Systems, Inc.Inventor: Jamie S. Henderson
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Publication number: 20030009215Abstract: A body compatible stent is formed of multiple filaments arranged in at least two sets of oppositely directed helical windings interwoven with one another in a braided configuration. Each of the filaments is a composite including a central core and a case surrounding the core. In the more preferred version, the core is formed of a radiopaque and relatively ductile material, e.g. tantalum or platinum. The outer case is formed of a relatively resilient material, e.g. a cobalt/chromium based alloy. Favorable mechanical characteristics of the stent are determined by the case, while the core enables in vivo imaging of the stent. The composite filaments are formed by a drawn filled tubing process in which the core is inserted into a tubular case of a diameter substantially more than the intended final filament diameter. The composite filament is cold-worked in several steps to reduce its diameter, and annealed between successive cold working steps.Type: ApplicationFiled: June 19, 2002Publication date: January 9, 2003Applicant: Schneider (USA) Inc., a Minnesota CorporationInventor: David W. Mayer
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Publication number: 20020052660Abstract: Leak and tear resistant grafts for repair and replacement of living animal tissue are disclosed. The grafts, which may be flat or tubular, are formed of interlaced filamentary members and have reinforced attachment regions defined by interlaced filamentary members of higher tensile strength. Higher strength is provided by use of high strength material, increased denier or number of plies of the filamentary members. High strength members inhibit propagation of tears which occur in the graft when the attachment region is pierced by sutures or staples. Filamentary members formed of textured, elastic or heat shrinkable yarns interlaced in the graft inhibit leakage.Type: ApplicationFiled: October 31, 2001Publication date: May 2, 2002Inventor: E. Skott Greenhalgh
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Patent number: 6190407Abstract: A variety of new ways can be used for associating antimicrobial elemental metal with a medical article. The associated antimicrobial metal reduces the risk of infection associated with the medical use of the medical article. New medical articles are produced by some of these new approaches. Some of the methods involve ways of adjusting the dissociation rate of associated elemental metal such that desired degrees of antimicrobial activity can be achieved over selected periods of time.Type: GrantFiled: December 31, 1998Date of Patent: February 20, 2001Assignee: St. Jude Medical, Inc.Inventors: Matthew F. Ogle, William R. Holmberg, Richard F. Schroeder, Donald S. Guzik, M. William Mirsch, II, Darrin J. Bergman, Hallie A. Finucane, Katherine S. Tweden