Made Of Synthetic Material Patents (Class 623/1.49)
  • Patent number: 10792391
    Abstract: A biodegradable magnesium alloy nerve conduit for nerve defect repair has multiple lines of through holes in the tube wall thereof, the through holes in each line are axially arranged along a circular tube at equal distances, and the through holes in adjacent lines are arranged in a staggered way. A method for preparing the nerve conduit includes steps of: (step 1) processing a 45-degree conical surface at one end of a magnesium alloy tube blank, carrying out extrusion, and obtaining a magnesium alloy intermediate tube material; (step 2) obtaining a capillary tube after carrying out multi-pass rolling and drawing on the magnesium alloy intermediate tube material; (step 3) carrying out stress relief annealing on the capillary tube, laser cutting and punching, and obtaining a porous conduit; and (step 4) carrying out acid pickling on the porous conduit, and then carrying out electrochemical polishing treatment, and obtaining the nerve conduit.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: October 6, 2020
    Assignees: SHANGHAI JIAO TONG UNIVERSITY, SHANGDONG ZHONGBAOKANG MEDICAL DEVICES CO., LTD
    Inventors: Guangyin Yuan, Wenjiang Ding
  • Patent number: 10323144
    Abstract: L-Polylactic acid and D-Polylactic acid biodegradable biopolymers are combined with torrefied biomass and a plasticizer to create a biodegradable cardstock composition. The biodegradable cardstock composition provides an alternative to conventional plastic cardstocks, which are manufactured using petroleum-based materials such polyvinyl chloride (PVC) or polystyrene (PS). The biodegradable cardstock described herein can be incorporated into a variety of end products such as key cards, driver licenses, security badges, calling cards, and other plastic cards, including those that have a magnetic strip containing stored data such as credit and debit cards.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: June 18, 2019
    Assignees: The United States of America, as represented by The Secretary of Agriculture, Lapol, LLC
    Inventors: William J. Orts, Allison Flynn, Lennard F. Torres, William E. Kelly
  • Patent number: 10279010
    Abstract: The present invention discloses methods and compositions for treating or ameliorating a condition associated with increased or decreased myofibroblast activities and use thereof.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: May 7, 2019
    Assignee: The Regents of the University of California
    Inventors: B. Chia Soo, Kang Ting, Zhong Zheng
  • Patent number: 10213583
    Abstract: Treating a treatment area in the vasculature includes a first catheter adapted for positioning at the treatment area, said first catheter including a first balloon having a transient radiopaque material corresponding to the treatment area. A second catheter adapted for positioning at the treatment area includes a treatment that substantially matches the transient radiopaque material, preferably so that the length and/or position of the treatment corresponds to the length and/or position of the transient radiopaque material. Related kits, assemblies, and methods are also described.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: February 26, 2019
    Assignee: CLEARSTREAM TECHNOLOGIES LIMITED
    Inventors: Stephanie Klocke, Rob Righi
  • Patent number: 9585985
    Abstract: An object to be solved by the present invention is to provide a method for preparing a composition prepared by firmly coating the surface of a material with a biopolymer, and a composition prepared by this method wherein the surface of a material is firmly coated with a biopolymer. The present invention provides a method for coating with a biopolymer, which comprises coating the surface of a synthetic polymer with a biopolymer dissolved in a solvent comprising an organic fluorine compound.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: March 7, 2017
    Assignee: FUJIFILM Corporation
    Inventors: Shouji Ooya, Tetsuo Hiratou
  • Patent number: 9427317
    Abstract: This device includes a hollow support delimiting, in the vicinity of a distal end, a transverse retention opening. It further includes an endoprosthesis which can be deployed between a state retracted against the support and an expanded state. The device further includes a filamentary connection forming a clamping ring surrounding the endoprosthesis and forming a loop engaged in the support through the retention opening. A retention rod mounted to be movable in the support, and the retention rod has a hook for retaining the loop. The displacement of the retention rod from a release position to a retention position brings about the tightening of the clamping ring.
    Type: Grant
    Filed: April 3, 2007
    Date of Patent: August 30, 2016
    Assignee: CORMOVE
    Inventor: Mikolaj Styrc
  • Patent number: 9402755
    Abstract: The present disclosure describes systems for endoluminal devices utilizing a sleeve for constraining an expandable device toward a constrained configuration suitable for endoluminal delivery to a treatment site along vasculature; and a mechanism for retracting at least a portion of the sleeve.
    Type: Grant
    Filed: January 16, 2013
    Date of Patent: August 2, 2016
    Assignee: W. L. GORE & ASSOCIATES, INC.
    Inventors: Patrick M. Norris, Matthew G. Sondreaal
  • Patent number: 9254350
    Abstract: Implantable medical devices having a metallic surface coated with a bioabsorbable primer polymer layer under a bioabsorbable drug polymer layer. Thus, in addition to the degradation of the drug polymer layer, there is degradation of the primer layer. The underlying metallic framework may or may not degrade depending on whether bioabsorbable or biostable metals are chosen.
    Type: Grant
    Filed: April 10, 2009
    Date of Patent: February 9, 2016
    Assignee: Medtronic Vascular, Inc.
    Inventors: Kishore Udipi, Ya Guo
  • Patent number: 9138335
    Abstract: A sealable vascular system includes an endovascular implant to be delivered in a compressed or folded state to an implantation site. The endovascular implant includes a tubular implant body and a sealable circumferential collar at said tubular implant body and including a variable sealing device and a control lead traversing from said variable sealing device to a user for controlling said variable sealing device by the user, said variable sealing device and said control lead being cooperatively operable to reversibly expand and contract said sealable circumferential collar such that said sealable circumferential collar is circumferentially adjustable during deployment thereof to achieve a repositionable fluid-tight seal between said sealable circumferential collar and the internal walls of the implantation site.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: September 22, 2015
    Assignee: Syntheon Cardiology, LLC
    Inventors: Richard George Cartledge, John P. Cartledge, Ralph Edward Gaskins
  • Patent number: 9101455
    Abstract: A system may include an endoluminal prosthesis and a guide wire. The prosthesis may include a tubular body including a graft material wall, a proximal end opening, a distal end opening, and a lumen extending longitudinally therein. The prosthesis may include first and second fenestrations in the graft material wall. The first and second fenestrations may be spaced from one another circumferentially about the tubular body. The guide wire may have a first end and a second end both extending from a region proximal of the proximal end opening. The guide wire may enter the proximal end opening, exit the first fenestration, partially traverse an exterior surface of the prosthesis, enter the second fenestration, and exit the proximal end opening. No portion of the guide wire may extend distally beyond the distal end opening.
    Type: Grant
    Filed: December 18, 2012
    Date of Patent: August 11, 2015
    Assignee: Cook Medical Technologies LLC
    Inventors: Blayne A. Roeder, Matthew S. Huser, Kelly Coverdale
  • Patent number: 9032607
    Abstract: A medical device-includes a polymer stent crimped to a catheter having an expansion balloon. The stent is crimped to the balloon by a process that includes heating the stent to a temperature below the polymer's glass transition temperature to improve stent retention without adversely affecting the mechanical characteristics of the stent when later deployed to support a body lumen.
    Type: Grant
    Filed: August 15, 2014
    Date of Patent: May 19, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Kevin F. Jow, Arlene Sucy Yang, Yunbing Wang, Kathleen W. Yan
  • Patent number: 9011516
    Abstract: Medical devices, such as endoprostheses, and methods of making the devices are described. In some embodiments, a medical device includes an elongated hollow body formed of a polymeric matrix containing one or more regions of a pre-determined weight percent of carbon nanotubes in general alignment in a pre-determined orientation. The medical device can have a compressed state with a first transverse dimension and an expanded state with a second relatively greater transverse dimension.
    Type: Grant
    Filed: June 15, 2007
    Date of Patent: April 21, 2015
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Jan Weber, Thomas J. Holman, Tracee Eidenschink
  • Patent number: 8992594
    Abstract: A tubular graft device is provided comprising a tubular member and a fiber matrix of one or more polymers about a circumference of the tubular member. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a harvested saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft and connecting the graft between a first body space and a second body space, such as the aorta and a location on an occluded coronary artery, distal to the occlusion.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: March 31, 2015
    Assignee: Neograft Technologies, Inc.
    Inventors: Lorenzo Soletti, Mohammed S. El-Kurdi, Jon McGrath, J. Christopher Flaherty
  • Patent number: 8986393
    Abstract: A radiation and radiochemically sterilized, multi-component, fiber-reinforced composite, absorbable/disintegratable urinogenital stent, such as an endoureteral stent, with radiomodulated residence time in the biological site of 1 to 10 weeks depending on the high energy radiation dose used for sterilization.
    Type: Grant
    Filed: November 22, 2011
    Date of Patent: March 24, 2015
    Assignee: Poly-Med, Inc.
    Inventors: Shalaby W. Shalaby, Kenneth W. Clinkscales, Kenneth D. Gray
  • Patent number: 8904619
    Abstract: A medical device- includes a polymer stent crimped to a catheter having an expansion balloon. The stent is crimped to the balloon by a process that includes heating the stent to a temperature below the polymer's glass transition temperature to improve stent retention without adversely affecting the mechanical characteristics of the stent when later deployed to support a body lumen.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: December 9, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Kevin F. Jow, Arlene Sucy Yang, Yunbing Wang, Kathleen W. Yan
  • Patent number: 8901248
    Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: December 2, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Shaina Brito, Frederick Strickler
  • Patent number: 8888838
    Abstract: An endoprosthesis fabricated from multi-phase ferrous steel. Endoprostheses can include a variety of devices such as staples, orthodontic wires, heart valves, filter devices, and stents, many of which devices are diametrically expandable devices. Multi-phase ferrous steels include dual phase steels and transformation induced plasticity steels (TRIP steels).
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: November 18, 2014
    Assignee: W. L. Gore & Associates, Inc.
    Inventor: Jeffrey S. Blanzy
  • Patent number: 8884184
    Abstract: An apparatus for athermal ablation of a workpiece. The apparatus may include a laser device to direct a laser beam at the workpiece to remove a plurality of sections from the workpiece by athermal ablation. The removal may occur in a plurality of discrete motions that cause the laser beam to trace along outer perimeters of the sections in a specific order maintaining mechanical stability of the plurality of sections. The apparatus may further include a process gas nozzle to deliver process gas coaxially with the laser beam to clear debris and cool the workpiece, and a workpiece holder to hold and maneuver the workpiece during the removal of the plurality of sections.
    Type: Grant
    Filed: August 11, 2011
    Date of Patent: November 11, 2014
    Assignee: Raydiance, Inc.
    Inventors: David Gaudiosi, Michael Greenberg, Michael Mielke, Tim Booth, Gordon Masor
  • Patent number: 8858618
    Abstract: Provided is a stent wherein the water-swellable polymer fine particles applied thereto rarely peel off even when the stent is deformed or when the water-swellable polymer fine particles are swollen. A stent wherein a plurality of water-swellable polymer fine particles are chemically fixed on the stent surface in a dispersed state is provided.
    Type: Grant
    Filed: September 6, 2010
    Date of Patent: October 14, 2014
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Takao Anzai, Yosuke Kuruma
  • Patent number: 8852263
    Abstract: The use of nucleating agents to manufacture polymeric stents is disclosed. The resulting stents may have increased crystallinity, decreased crystal size, increased mechanical properties, and faster degradation times.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: October 7, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventor: Yunbing Wang
  • Publication number: 20140271774
    Abstract: Coatings for a surface, especially a priming coating, of the present invention have been found to be durable, resistant to oxidative degradation, erosion and depolymerisation, stable to sterilization and low particulating, and are easily applied to the required surface of a substrate in a surface-independent manner. Such coatings, when used as priming coatings to be coated with a subsequent coating, in at least some embodiments, form exterior coatings which are also highly durable and are stable to sterilisation and aging.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: W. L, Gore & Associates, Inc,
    Inventors: Paul D. Drumheller, Charles D. Claude
  • Publication number: 20140257275
    Abstract: A method of creating a thermochromic artificial blood vessel includes physically cross-linking a polyvinyl alcohol solution in a mold shaped to mimic a blood vessel to create an artificial blood vessel. The artificial tissue is then chemically cross-linked with a solution including a chemical cross-linking reagent. A coagulation solution is then applied to the artificial blood vessel to both inhibit the chemical cross-linking and promote physical cross-linking of the artificial blood vessel. The artificial blood vessel can be used to test an ablation catheter. The vessel, when heated by the ablation catheter, changes color and/or transparency at locations where the temperature of artificial blood vessel increases.
    Type: Application
    Filed: March 6, 2013
    Publication date: September 11, 2014
    Applicant: ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
    Inventors: Euhnee Cho, Valentine Kozov, Sukanya Varadharajan, Steven N. Willard
  • Patent number: 8795221
    Abstract: A bypass device for influencing blood pressure, including an implant with a volumetric chamber, having a connector or connecting means for connecting the volumetric chamber to a natural cardiovascular system, and having an adaptor or adaptation means, by which a change in volume of a volume of the volumetric chamber is enabled or effected upon a pressure change in the cardiovascular system or in the volumetric chamber. According to this invention, a change in volume in a lower pressure range between 50 mmHg and a pressure threshold value amounting to at least 100 mmHg amounts to at most 10 cm3, and in an upper pressure range between the pressure threshold value and 150 mmHg amounts to at least 10 cm3. With the device according to this invention, high blood pressure can be reduced in a carefully directed way.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: August 5, 2014
    Assignee: E.S. Bio-Tech Limited
    Inventor: Mirko Doss
  • Patent number: 8784477
    Abstract: A vascular prosthesis and method are disclosed comprising a first flexible stent having a lattice structure with a compacted configuration and an expanded configuration, a second flexible stent inside the first flexible stent to form a tubular structure, a first film layer of graft material such as expanded polytetrafluoroethylene sandwiched between the first and second flexible stents, and a second film layer of expanded polytetrafluoroethylene sandwiched between the first and second flexible stents, the second layer having a higher rigidity and a lower plasticity than the first layer.
    Type: Grant
    Filed: January 5, 2011
    Date of Patent: July 22, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Rainer Bregulla, Gunther Stockert
  • Patent number: 8772368
    Abstract: A bioabsorbable blend comprising poly(L-lactide) (PLLA) and a phosphorylcholine group-containing copolymer (PPCP) capable of enduring the mechanical strength of blood vessel walls and applicable for fabricating cardiovascular devices was developed. The blend acts as a scaffold to support blood vessel walls during vascular healing and undergoes biodegradation in vivo after vascular healing is complete. Furthermore, the blend can prevent the formation and adsorption of thrombi.
    Type: Grant
    Filed: September 11, 2013
    Date of Patent: July 8, 2014
    Assignees: Suntech Co., Ltd.
    Inventors: Hyung-Il Kim, Kazuhiko Ishihara
  • Patent number: 8752266
    Abstract: A medical device-includes a polymer stent crimped to a catheter having an expansion balloon. The stent is crimped to the balloon by a process that includes heating the stent to a temperature below the polymer's glass transition temperature to improve stent retention without adversely affecting the mechanical characteristics of the stent when later deployed to support a body lumen.
    Type: Grant
    Filed: August 22, 2012
    Date of Patent: June 17, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Kevin F. Jow, Arlene Sucy Yang, Yunbing Wang, Kathleen W. Yan
  • Patent number: 8752265
    Abstract: A medical device-includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the balloon by a process that includes inflating the delivery balloon during a diameter reduction to improve scaffold retention. A crimping temperature is maintained at about the onset of glass transition of the polymer material to facilitate more rapid stabilization of mechanical properties in the scaffold following crimping.
    Type: Grant
    Filed: May 13, 2011
    Date of Patent: June 17, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventor: Yunbing Wang
  • Patent number: 8747879
    Abstract: The invention provides a method for fabricating an implantable medical device to increase biocompatibility of the device, the method comprising: heat setting a polymer construct, wherein the polymer construct is at a temperature range of from about Tg to about 0.6(Tm?Tg)+Tg such that the set polymer construct comprises a crystalline structure having crystals at a size less than about 2 microns; and fabricating an implantable medical device from the heat set polymer construct.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: June 10, 2014
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, David C. Gale
  • Patent number: 8747878
    Abstract: A method of fabricating an implantable medical device that includes deforming and heating setting a polymer construct, for use in fabricating the device, in a temperature range in which the crystal nucleation rate is greater than the crystal growth rate is disclosed.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: June 10, 2014
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, David C. Gale
  • Patent number: 8709074
    Abstract: A device for treatment of mitral annulus dilation is disclosed, wherein the device comprises two states. In a first of these states the device is insertable into the coronary sinus and has a shape of the coronary sinus. When positioned in the coronary sinus, the device is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced.
    Type: Grant
    Filed: February 6, 2012
    Date of Patent: April 29, 2014
    Assignee: Edwards Lifesciences AG
    Inventors: Jan Otto Solem, Per-Ola Kimblad, Randolf von Oepen, Bodo Quint, Gerd Seibold, Kenneth J. Michlitsch, Suk-Woo Ha, Karl-Ludwig Eckert, Ib Joergensen, Stevan Nielsen
  • Patent number: 8703293
    Abstract: Provided herein re a composition and a coating or a device (e.g., absorbable stent) that includes a PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid biocompatible polymer and the methods of use thereof.
    Type: Grant
    Filed: April 1, 2010
    Date of Patent: April 22, 2014
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Lothar W. Kleiner, Connie S. Kwok
  • Patent number: 8696733
    Abstract: An implantable prosthesis, including a generally tubular substrate and a continuous shape memory member disposed over the outer surface of the substrate. The shape memory member may include a series of zig-zag struts alternating between a first strut with a first length and a second strut with a second length different from the first length. A graft member may be positioned over the substrate and shape memory member.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: April 15, 2014
    Assignee: C. R. Bard, Inc.
    Inventors: David L. Bogert, Chris Steadham
  • Patent number: 8685082
    Abstract: The present invention provides a base material which can be formed into valved lumen shape tissue having an ampulla and a leaflet consisting of body tissue. Specifically, the base material includes a first column 5 that forms an upstream tubular section 4 of a blood vessel 3, a second column 7 that forms a downstream tubular section 6 of the blood vessel 3, a plurality of bulges 10 for forming an ampulla 8 and a leaflet 9 of the blood vessel 3, and engagement means 11 that causes the bulge 10 to engage the first column 5 and/or the second column 7. The engagement means 11 includes recesses 15a and 15b in axial end surfaces of one or both of the first column 5 and the second column 7, and an engagement section 18 that overhangs from a bulge body 17 and engages the recesses. An outer peripheral surface of the body 17 of the bulge 10 is an ampulla forming surface 20, and a gap provided between the bulge body 17 and the first column 5 and/or the second column 7 is a leaflet forming section 22.
    Type: Grant
    Filed: November 16, 2011
    Date of Patent: April 1, 2014
    Assignee: National Cerebral and Cardiovascular Center
    Inventors: Yasuhide Nakayama, Tomonori Oie
  • Patent number: 8652284
    Abstract: A self-sealing vascular graft with kink resistance is described. The vascular graft includes a substrate that can be ePTFE, having a self-sealing region that may include several layers of material. The central section of the vascular graft may be constructed differently from surrounding self-sealing regions, in order to provide kink resistance following the clamping of the graft. Also described is a graft with a flared cuff attached to one or both ends, the attachment or transition region including reinforcement beading.
    Type: Grant
    Filed: November 21, 2011
    Date of Patent: February 18, 2014
    Assignee: C. R. Bard, Inc.
    Inventors: David L. Bogert, Jamie Abbott
  • Patent number: 8636792
    Abstract: The disclosure provides biodegradable implantable devices such as a stent comprising a biodegradable polymeric wherein the polymeric material is treated to control crystallinity and/or Tg. The stent is capable to expand at body temperature from a crimped configuration to a deployed diameter and have sufficient strength to support a body lumen.
    Type: Grant
    Filed: July 2, 2012
    Date of Patent: January 28, 2014
    Assignee: Elixir Medical Corporation
    Inventors: Xiaoxia Zheng, John Yan, Vinayak Bhat
  • Publication number: 20140018909
    Abstract: Disclosed is a medical device treated with a phenolic compound and a process for treating a device with the phenolic compound. For example, a collagen or elastin-based scaffold can be treated with pentagalloyl glucose (PGG). The treated scaffold can become resistant to glycoxidative stress associated with advanced glycation end products (AGEs) that are present in a hyperglycemic environments associated with diabetes mellitus. The treated scaffold can exhibit a reduced increase in stiffness as compared to an untreated scaffold. The treated scaffold can also exhibit reduced inflammation without negatively affecting the ability of the scaffold to remodel in vivo.
    Type: Application
    Filed: July 10, 2013
    Publication date: January 16, 2014
    Inventors: Agneta Simionescu, Dan Simionescu, James Chow
  • Publication number: 20130338762
    Abstract: Bioabsorbable scaffolds having high crush recoverability, high fracture resistance, and reduced or no recoil due to self expanding properties at physiological conditions are disclosed The scaffolds are made from a block copolymer of PLLA and a hydrophilic polymer.
    Type: Application
    Filed: June 15, 2012
    Publication date: December 19, 2013
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Dudley S. Jayasinghe, Dariush Davalian, Ronald A. Farnbach
  • Patent number: 8597716
    Abstract: Methods for increasing the fracture resistance of a polymer stent's drug-polymer coating and scaffolding including applying a coating and crimping using techniques that increase the resistance to fracture in the coating layer and scaffolding and scaffolding.
    Type: Grant
    Filed: June 23, 2009
    Date of Patent: December 3, 2013
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Dan Castro, Yunbing Wang
  • Publication number: 20130317601
    Abstract: The present invention is directed to a device that permits a permanent aperture to be formed in a wall, or other partition, of an implantable medical device. The present invention maintains the continuity and fluid-retaining properties of the implantable medical device by providing a breachable barrier material fully covering an opening delimited by a deformable framework. The invention is accessed with conventional interventional surgical instruments that disrupt and displace the barrier material. Following disruption of the barrier material, the opening is enlarged with surgical instruments to form a permanent framed aperture in the wall of the implantable medical device. The permanent framed aperture provides fluid communication across the wall of the implantable medical device.
    Type: Application
    Filed: July 31, 2013
    Publication date: November 28, 2013
    Applicant: W. L. Gore & Associates, Inc.
    Inventors: Edward H. Cully, Warren J. Cutright, Craig T. Nordhausen, Michael J. Vonesh, James T. Walter
  • Patent number: 8562671
    Abstract: The invention relates to scaffolds for artificial heart valves and vascular structures comprising a biocompatible block copolymer. A method and means for producing said scaffold are also provided.
    Type: Grant
    Filed: June 4, 2007
    Date of Patent: October 22, 2013
    Assignee: Eidgenossische Technische Hochschule Zurich
    Inventor: Peter Neuenschwander
  • Publication number: 20130261735
    Abstract: Stents or scaffolds made from magnesium or magnesium alloys including additives or barrier coatings that modify the corrosion rate of the stent are disclosed. Methods of forming barrier coatings that modify the corrosion rate of the stent are disclosed.
    Type: Application
    Filed: March 30, 2012
    Publication date: October 3, 2013
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Stephen D. Pacetti, Yunbing Wang, Ni Ding
  • Publication number: 20130197628
    Abstract: Copolymer-modified nanoparticles produced by a process in which nanoparticles are ablated by laser radiation from a surface of a substrate in a liquid include an amphiphilic copolymer.
    Type: Application
    Filed: April 19, 2011
    Publication date: August 1, 2013
    Applicants: AESCULAP AG, Max Planck Gesellschaft zur Foerderung der Wissenschaften e.V., LASER ZENTRUM HANNOVER E.V.
    Inventors: Stephan Barcikowski, Christin Menneking, Markus Klapper, Klaus Müllen, Michael Hoffmann, Simon Stelzig, Dennis Langanke, Helmut Goldmann
  • Patent number: 8486135
    Abstract: This invention relates to implantable medical devices, such as stents, fabricated from hyperbranched-like polymers, comb-like polymers, star polymers, dendrimer-like star polymers, dendrimers, and mixtures thereof.
    Type: Grant
    Filed: April 9, 2007
    Date of Patent: July 16, 2013
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, David C. Gale, Bin Huang, Mikael O. Trollsas, Thierry Glauser, Florian Ludwig
  • Publication number: 20130166019
    Abstract: The present invention relates to a medical device or implant made at least in part of a high strength, low modulus metal alloy comprising Niobium, Tantalum, and at least one element selected from the group consisting of Zirconium, Tungsten, and Molybdenum. The medical devices according to the present invention provide superior characteristics with regard to bio-compatibility, radio-opacity and MRI compatibility.
    Type: Application
    Filed: February 21, 2013
    Publication date: June 27, 2013
    Inventors: Hans Jurgen Wachter, Jens Trötzschel, Randolf Von Oepen
  • Publication number: 20130150952
    Abstract: A biodegradable polymer stent with radiopacity and a method of making and using a stent with enhanced mechanical strength and/or controlled degradation for use in a bodily lumen is described.
    Type: Application
    Filed: February 12, 2013
    Publication date: June 13, 2013
    Applicant: Biosensors International Group Ltd.
    Inventor: Biosensors International Group Ltd.
  • Patent number: 8460693
    Abstract: The invention relates to an intraluminal device, in particular an intraluminal prosthesis, shunt, catheter or local drug delivery device. In order to increase the bio-compatibility of this device, it is provided with at least one coating. The coating contains a therapeutic agent which is comprised in a matrix that sticks to the intraluminal device. Instead of being formed by a little bio-compatible polymer, the matrix is formed by a bio-compatible oil or fat, such as cod-liver oil or olive oil. Preferably, the bio-compatible oil or fat further comprises alfa-tocopherol.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: June 11, 2013
    Assignee: Atrium Medical Corporation
    Inventors: Maria Dhondt, Ivan De Scheerder, Pierre Jacobs, Johan Martens
  • Publication number: 20130144377
    Abstract: A tubular conduit is disclosed. The tubular conduit comprises a tubular portion made from a flexible material and an axially extending external helical formation located around the outside of the tubular portion. The external helical formation is for supporting the tubular portion. Optionally the tubular portion also comprises an axially extending internal helical protrusion, which imparts a helical flow to a fluid passing through the tubular portion. It is preferred that the tubular conduit is a vascular graft.
    Type: Application
    Filed: November 12, 2012
    Publication date: June 6, 2013
    Applicant: VASCULAR FLOW TECHNOLOGIES LIMITED
    Inventor: VASCULAR FLOW TECHNOLOGIES LIMITED
  • Patent number: 8449601
    Abstract: Medical devices including an organic-inorganic composite material, including methods of making the devices, are disclosed.
    Type: Grant
    Filed: November 19, 2002
    Date of Patent: May 28, 2013
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: Jan Weber
  • Patent number: 8377533
    Abstract: A bioabsorbable stent and method of forming the same including a stent scaffolding formed from polymer layers with different degradation rates is disclosed. The polymer layers include an abluminal layer, a luminal layer, and optionally one or more middle layers. A degradation rate of the layers increases from the luminal layer to the abluminal layer.
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: February 19, 2013
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventor: Yunbing Wang
  • Patent number: 8318618
    Abstract: A mat having a highly uniform porosity distribution is produced by consolidating 15 or more layers of melt blown webs (or the like) having different orientations. Control over the porosity is provided by using webs that exhibit a narrow, unimodal distribution of fiber diameters over the bulk of its distribution, such as in the top 80%. A compliance of the mats can be chosen by selecting a number and orientation of the webs. It is thus possible to produce mats that are good candidates for vascular grafts, for example. The uniformity of the porosity within the range of 6 ?m to 30 ?m permits seeding of the vascular graft with endothelial and smooth muscle cells. The mats have the demonstrated ability to retain, and support growth of, smooth muscle cells and endothelial cells.
    Type: Grant
    Filed: May 21, 2008
    Date of Patent: November 27, 2012
    Assignee: National Research Council of Canada
    Inventors: Abdellah Ajji, Marie Moreno, Martin Bureau