Bladder, Kidney, Lung, Or Stomach Patents (Class 623/23.65)
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Patent number: 7628821Abstract: A prosthetic device is described that is positionable within the gastro-esophageal junction region of a patient. The prosthetic device includes a proximal opening and a distal orifice that is adjustable in size prior to and/or following implantation. During use, the prosthetic device is attached to tissue of the gastro-esophageal junction region of the patient, with the device positioned such that food ingested by the patient passes from the esophagus through the proximal opening into the interior of the prosthetic device, and eventually exits the prosthetic device via the distal opening.Type: GrantFiled: August 2, 2005Date of Patent: December 8, 2009Assignee: Barosense, Inc.Inventors: Richard S. Stack, Fred E. Silverstein, Nathan Every, William L. Athas, Michael S. Williams, Richard A. Glenn, John Lunsford, Dan Balbierz
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Publication number: 20090299486Abstract: Gastrointestinal prosthesis for restraining the rate of the gastric digestion consists of a compressible proximal member connected by a string to a distal member, to be introduced into the intestine. The proximal member has an internal space, which is opened to the gastric lumen and may include passageways for the gastric content as well as open grooves or niches disposed on its external wall. The volume of a proximal member compressed by the gastric wall cannot get smaller than a lower threshold. Anchoring the gastrointestinal prosthesis at its desired location is accomplished by means of the proximal member the geometrical shape of which conforms the geometrical shape of a portion of the gastric lumen; as well as by means of the geometrical shape of the distal member which conforms the geometrical shape of a segment of the duodenum and/or a segment of the intestine.Type: ApplicationFiled: June 28, 2007Publication date: December 3, 2009Applicant: Slimedics Ltd.Inventors: Shaul Shohat, Raz Bar-On
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Publication number: 20090299487Abstract: A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.Type: ApplicationFiled: August 10, 2009Publication date: December 3, 2009Inventors: Richard S. Stack, Richard A. Glenn, Trevor J. Moody, Fred E. Silverstein, Nathan Every, William S. Eubanks, JR.
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Publication number: 20090281634Abstract: A prosthetic device for the intestine is disclosed that bypasses an enterocutaneous fistula so that the intestinal tract can properly function without bowel contents leaking onto the skin. The prosthetic device includes means to securely connect and seal it to the intestine, means to push bowel contents through it, and means to prevent the backflow of bowel contents through the digestive tract.Type: ApplicationFiled: May 8, 2009Publication date: November 12, 2009Applicant: The University of Mississippi Medical Center Research Development FoundationInventors: Thomas L. Abell, Christopher J. Lahr, Derek F. Lahr
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Patent number: 7608578Abstract: A method of controlling obesity by injecting bio-compatible bulking material into the pyloric sphincter area of the stomach. The injection of this material bulks the pyloric sphincter, retarding stomach emptying and producing a feeling of satiation in the patient. The method may be supplemental and augmented by inducing flaccid paralysis of the stomach by injecting botulinum toxin into the muscle tissue of the antrum or fundus of the stomach.Type: GrantFiled: August 9, 2001Date of Patent: October 27, 2009Assignee: Temple University - Of the Commonwealth System of Higher EducationInventor: Larry S. Miller
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Patent number: 7608114Abstract: Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal implant device is anchored in the stomach and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor for anchoring the device to the stomach and a flexible sleeve. When implanted within the intestine, the sleeve can limit the absorption of nutrients, delay the mixing of chyme with digestive enzymes, altering hormonal triggers, providing negative feedback, and combinations thereof. The anchor is collapsible for endoscopic delivery and removal.Type: GrantFiled: December 13, 2005Date of Patent: October 27, 2009Assignee: GI Dynamics, Inc.Inventors: Andy H. Levine, John F. Cvinar, David A. Melanson, John C. Meade
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Patent number: 7601178Abstract: The invention relates to an implantable stomach prosthesis for surgically replacing or augmenting all or part of the antrum and/or pylorus of a stomach. The prosthesis controls the passage of food from the stomach to the small intestine. The prosthesis may be configured to chum ingested material and release it from the stomach through a prosthetic pyloric valve. At least one expandable member is arranged to be expanded to control the passage of food and/or to mimic the churning action of a patient's stomach. The prosthesis includes an outer support structure, a flexible inner member forming a conduit for the movement of material, and at least one expandable member located between the outer support structure and inner member. An implantable pump system is provided for inflating and deflating the expandable member(s).Type: GrantFiled: February 6, 2006Date of Patent: October 13, 2009Assignee: Python Medical, Inc.Inventor: Mir A. Imran
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Publication number: 20090248171Abstract: Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal implant device is anchored in the stomach and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor for anchoring the device to the stomach and a flexible sleeve. When implanted within the intestine, the sleeve can limit the absorption of nutrients, delay the mixing of chyme with digestive enzymes, altering hormonal triggers, providing negative feedback, and combinations thereof. The anchor is collapsible for endoscopic delivery and removal.Type: ApplicationFiled: May 26, 2009Publication date: October 1, 2009Applicant: GI Dynamics, Inc.Inventors: Andy H. Levine, John F. Cvinar, David A. Melanson, John C. Meade
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Publication number: 20090240340Abstract: Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal implant device is anchored in the stomach and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor for anchoring the device to the stomach and a flexible sleeve. When implanted within the intestine, the sleeve can limit the absorption of nutrients, delay the mixing of chyme with digestive enzymes, altering hormonal triggers, providing negative feedback, and combinations thereof. The anchor is collapsible for endoscopic delivery and removal.Type: ApplicationFiled: May 26, 2009Publication date: September 24, 2009Applicant: GI Dynamics, Inc.Inventors: Andy H. Levine, John F. Cvinar, David A. Melanson, John C. Meade
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Publication number: 20090234461Abstract: A prosthetic mesh and method of use in surgical methods for closure of abdominal incisions and prosthetics for repair of ventral hernias. The mesh provides for a new prosthetic that can be used for closure of laparotomy incisions, in patients at high risk for hernia formation, and in the repair of existing ventral hernias. The mesh utilizes existing multi laminar technology for intra peritoneal mesh, and fashions it in the shape of an intact Rectus Sheath. The mesh matrix can be made of any of the various absorbable or permanent polymer filaments that are woven or knitted into a scaffold for added strength to the abdominal wall closure during the healing phase, and for delivery of bio active substances that contribute to a biochemical milieu that contributes to favorable healing. A permanent non absorbable prosthesis will be desirable in certain circumstances and for particular patients, a slowly dissolving mesh would be ideal in most cases.Type: ApplicationFiled: March 14, 2008Publication date: September 17, 2009Inventor: Robert D. Rehnke
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Patent number: 7572221Abstract: A cartilaginous structural member (CSM) for use in penile reconstruction, for the correction of developmental defects, postoperative reconstruction, and for reconstructive preprosthetic surgery. The cartilaginous structural member (CSM) comprise of live cells seeded onto pre-formed shaped structure which may be biodegradable. The live cells may comprise chondrocyte and the cartilaginous structural member (CSM) for use in reconstructive surgery may be constructed of polyglycolic acid. The implant structure is applicable to use for the regeneration and reconstruction or augmentation of semirigid members of the body such as the penis, nose, ear and locations which naturally has cartilage. Further, the cartilaginous structural member (CSM) may be used in plastic surgery such as, for example, breast augmentation or pectoral augmentation.Type: GrantFiled: March 25, 2003Date of Patent: August 11, 2009Assignee: Children's Medical Center CorporationInventors: Anthony Atala, James J. Yoo
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Patent number: 7569076Abstract: The invention is directed to methods and devices for the reconstruction, repair, augmentation or replacement of laminarily organized organs or tissue structures in a patient in need of such treatment. The device comprises a biocompatible synthetic or natural polymeric matrix shaped to conform to at least a part of the luminal organ or tissue structure with a first cell population on or in a first area and a second cell population such as a smooth muscle cell population in a second area of the polymeric matrix. The method involves grafting the device to an area in a patient in need of treatment. The polymeric matrix comprise a biocompatible and biodegradable material.Type: GrantFiled: March 21, 2003Date of Patent: August 4, 2009Assignee: Children's Medical Center CorporationInventor: Anthony Atala
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Publication number: 20090164028Abstract: An intragastric member and method of delivery thereof are described. Delivery of the intragastric member is enabled by partitioning the intragastric member into discrete bundles with retaining members that are circumferentially disposed along the longitudinal length of the intragastric member. Formation of the intragastric member into bundles facilitates controlled delivery into the gastric lumen. The use of suture ties enables deployment of the intragastric member into the gastric lumen. The distal ends of the suture ties are affixed to the bundles. Pulling on the proximal free end of each of the suture ties enables the corresponding bundles to be advanced distally along a delivery tube.Type: ApplicationFiled: December 21, 2007Publication date: June 25, 2009Applicant: Wilson-Cook Medical Inc.Inventor: Steve Kaipin Chen
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Publication number: 20090138094Abstract: A medical implant is disclosed, said implant having a flexible hollow body (1) which can be implanted inside the stomach (8) of a patient and which has a first tube-like end section (2) and a second tube-like end section (3), wherein the first tube-like end section (2) is dimensioned such that it can be fitted into the esophagus (7) of the patient, and the second tube-like end section (3) is dimensioned such that it can be connected to the small intestine loop (9) of the patent in a sealing manner.Type: ApplicationFiled: January 27, 2009Publication date: May 28, 2009Inventor: Marc O. Schurr
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Publication number: 20090125119Abstract: Described are medical graft products, systems, and methods useful for treating fistulae, particularly enterocutaneous fistulae. Certain products of the invention are configured to have portions residing in and around a primary fistula opening in a wall of the alimentary canal. One such product includes a biocompatible graft body which is configured to block at least the primary opening. The graft body includes a capping member connected to an elongate plug member. The capping member is configured to contact portions of the alimentary canal wall adjacent to the primary opening, and the elongate plug member is configured to extend into at least a portion of the fistula. A graft product of this sort may be particularly adapted to allow a portion of the capping member to be positioned alongside an exterior, lateral surface of the plug member, e.g., when placed in a delivery device lumen. Such a capping member may be hingedly or non-hingedly coupled to the elongate plug member.Type: ApplicationFiled: November 12, 2008Publication date: May 14, 2009Inventors: F. Joseph Obermiller, Steve Chen
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Patent number: 7513914Abstract: A medical implant is disclosed, said implant having a flexible hollow body (1) which can be implanted inside the stomach (8) of a patient and which has a first tube-like end section (2) and a second tube-like end section (3), wherein the first tube-like end section (2) is dimensioned such that it can be fitted into the esophagus (7) of the patient, and the second tube-like end section (3) is dimensioned such that it can be connected to the small intestine loop (9) of the patent in a sealing manner.Type: GrantFiled: November 25, 2003Date of Patent: April 7, 2009Inventor: Marc O. Schurr
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Publication number: 20090076622Abstract: A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.Type: ApplicationFiled: September 12, 2008Publication date: March 19, 2009Applicant: PNEUMRX, INC.Inventors: David Thompson, Patrick Wu, David Lehrberg, Mark L. Mathis, Michael Boutillette
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Publication number: 20090076623Abstract: The invention provides improved medical devices, therapeutic treatment systems, and treatment methods for treatment of the lung. A lung volume reduction system includes an implantable device having an elongate body that is sized and shaped for delivery via the airway system to a lung airway of a patient. The implant is inserted and positioned while the implant is in a delivery configuration, and is reconfigured to a deployed configuration so as to locally compress adjacent tissue of the lung, with portions of the elongate body generally moving laterally within the airway so as to laterally compress lung tissue. A plurality of such implants will often be used to treat a lung of a patient.Type: ApplicationFiled: September 12, 2008Publication date: March 19, 2009Applicant: PNEUMRX, INC.Inventors: Mark L. Mathis, David Thompson, Nathan Aronson, Patrick Wu
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Publication number: 20090062927Abstract: The present invention relates to devices used in the management of bodily airways including tracheostomy tubes, laryngectomy tubes, bronchial stents, bronchial Y-tubes, bronchial TY-tubes, and nasal stents. The devices may comprise a protective coating to prevent the accumulation of mucus, crusting and granulation on or around airway management devices, as well as prevent adhesion to tissues which can cause bleeding upon removal, and prevent build-up of blood, or blood clots, to the stent.Type: ApplicationFiled: September 19, 2008Publication date: March 5, 2009Inventors: Lewis H. Marten, Dennis Creedon
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Patent number: 7479161Abstract: An artificial urinary diversion system is disclosed, which consists of a first area with at least one outlet, a second area, and a third area with at least one inlet for accommodating a urinary bladder. The second area is arranged between the first area and the third area, and that the cross-sectional surfaces of the first and/or second areas which are perpendicular to the axial alignment of the urinary diversion system are smaller than the cross-sectional surface of the third area, thereby providing a shape that can be adapted to almost any patient. These artificial urinary diversion systems provide adaptable systems that can be produced without previous direct or indirect determination of the potentially available volume for the system, and that facilitate an as effective as possible determination and utilization during the surgical phase of the volume available in the patient.Type: GrantFiled: March 17, 2000Date of Patent: January 20, 2009Inventors: Helmut Wassermann, Dieter Jocham
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Publication number: 20090018668Abstract: The invention relates to a method of separating components of a fluid mixture comprising the steps of providing a fluid, providing a sorbent structure (120), sorbing a first component of the fluid, desorbing the first component, and electrokinetically biasing the first component in a direction other than the vector of the fluid mixture.Type: ApplicationFiled: December 8, 2004Publication date: January 15, 2009Applicant: SEPARATION DESIGN GROUP, LLCInventor: Stephen Douglas Galbraith
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Publication number: 20090012626Abstract: A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.Type: ApplicationFiled: July 2, 2008Publication date: January 8, 2009Applicant: PNEUMRX, INC.Inventors: David THOMPSON, Nathan ARONSON, Patrick WU, David LEHRBERG, Mark L. MATHIS, Michael BOUTILLETTE, Jaime VASQUEZ
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Patent number: 7462162Abstract: This is directed to methods and devices suited for maintaining an opening in a wall of a body organ for an extended period. More particularly devices and methods are directed maintaining patency of channels that alter gaseous flow within a lung to improve the expiration cycle of, for instance, an individual having chronic obstructive pulmonary disease.Type: GrantFiled: July 19, 2004Date of Patent: December 9, 2008Assignee: Broncus Technologies, Inc.Inventors: Loc Phan, Ed Roschak
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Publication number: 20080283065Abstract: A mechanical device and/or chemical process is utilized to maintain luminal patency in conduits or other devices implanted in the lung or lungs of a patient. The mechanical device and/or chemical process ensures that air flows freely through a conduit implanted through an anastomosis into a lung. The device is suitable for use in conjunction with ventilation bypass treatments for chronic obstructive pulmonary disease.Type: ApplicationFiled: February 21, 2008Publication date: November 20, 2008Applicant: PORTAERO, INC.Inventors: Asia Chang, Scott M. Russell, Don Tanaka
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Patent number: 7442546Abstract: A method of immunomodulation by contacting the bodily fluid of a patient with renal tubule cells outside of the kidney.Type: GrantFiled: February 25, 2003Date of Patent: October 28, 2008Assignee: The Regents of the University of MichiganInventor: H. David Humes
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Publication number: 20080255678Abstract: The invention relates to a medical apparatus including a device used in the treatment of weight loss, obesity and potentially other associated health problems, e.g., type II diabetes. The device is used to impede absorption of nutrients within the gastrointestinal tract, i.e., bypassing a portion of the gastrointestinal tract. The medical apparatus enables implantation of the device using minimally invasive techniques, such a transesophageal approach under visualization. The device may be implanted via a working channel of a medical scope, e.g., an endoscope or in combination with a medical scope.Type: ApplicationFiled: April 11, 2008Publication date: October 16, 2008Inventors: Edward H. Cully, James Goepfrich, Joanne Hopmeyer, Edward E. Shaw
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Publication number: 20080249635Abstract: An obesity treatment device comprises a filament filler material movable between a substantially straight insertion/removal configuration and an operative configuration in which the filament extends along a predetermined curve to occupy a selected volume within the stomach and a retrieval device connected to a proximal end of the filler material facilitating grasping and withdrawal of the filler material. A method of treating obesity, comprises inserting to a desired position within the GI tract a filament filler in a substantially straight configuration and moving the filler into an operative configuration in which the filler curves along a predetermined path to define a desired volume in combination with, after a predetermined treatment period has elapsed, collapsing the filler into the substantially straight configuration for trans-oral removal.Type: ApplicationFiled: March 20, 2008Publication date: October 9, 2008Inventors: Barry Weitzner, Stephen Moreci
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Publication number: 20080234834Abstract: A gastrointestinal implant device includes a flexible, floppy sleeve, open at both ends, that extends into the duodenum. The device further includes a collapsible anchor coupled to the proximal portion of the sleeve. The device further includes a drawstring that is threaded through a proximal end of the anchor, and barbs that extend from the exterior surface of the anchor. The collapsible anchor can be a wave anchor. The drawstring can be used to collapse at least a proximal portion of the implant device. This is useful in removing or repositioning the implant device.Type: ApplicationFiled: December 20, 2007Publication date: September 25, 2008Applicant: GI Dynamics, Inc.Inventors: John C. Meade, Andy H. Levine, David A. Melanson, Ronald B. Lamport, John F. Cvinar
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Publication number: 20080221703Abstract: Devices for loading a collapsible implant onto a delivery catheter. In one aspect, a loading device comprises an outer tubular structure and an inner tubular structure. The outer tubular structure comprises a narrowing passage configured to receive a catheter at one end and a collapsible implant at another end. The inner tubular structure is configured to move slidably and co-axially within the outer tubular structure. The inner tubular structure comprises a carrier pin configured to move within the narrowing passage as the inner tubular structure slides into the outer tubular structure. The sliding of the inner tubular structure into the outer tubular structure causes an implant mounted on the carrier pin to collapse as the implant moves through the narrowing passage and into the distal end of a catheter.Type: ApplicationFiled: March 6, 2008Publication date: September 11, 2008Applicant: PULMONxInventors: LIKE QUE, Hoang Nguyen, Son Gia, Ajitkumar Nair, Roger Farnholtz, George Surjan, Andrew Huffmaster, Jeffrey Lee
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Publication number: 20080221702Abstract: An intragastric and/or intragastrointestinal device may include a prosthesis, which may reside within the gastrointestinal tract lumen. The device may include a restrictive element that constricts or restricts the gastrointestinal tract lumen, limiting the amount of food and/or fluid an individual consumes.Type: ApplicationFiled: November 8, 2005Publication date: September 11, 2008Inventors: Jeffrey M. Wallace, Peter J. Lukin, Donald Coelho, Gregory Amante
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Publication number: 20080208356Abstract: A device for inducing weight loss in a patient includes a tubular prosthesis positionable at the gastro-esophageal junction region, preferably below the z-line. In a method for inducing weight loss, the prosthesis is placed such that an opening at its proximal end receives masticated food from the esophagus, and such that the masticated food passes through the pouch and into the stomach via an opening in its distal end.Type: ApplicationFiled: December 18, 2007Publication date: August 28, 2008Inventors: Richard S. STACK, Richard A. GLENN, William L. Athas, Michael S. Williams
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Publication number: 20080208357Abstract: Method for treating a Roux-en-Y patient having fistulas and leaks as a result of bariatric surgery. A gastrointestinal implant device is anchored in the esophagus and extends through a stomach pouch into an intestine anastomosed to the stomach pouch to prevent fistulas and other damaged tissue from making contact with food and fluids entering the esophagus. The gastrointestinal implant device includes an unsupported flexible sleeve and an anchor coupled to a proximal portion of the sleeve. The flexible sleeve is open at both ends, and adapted to extend below a jejunum. The anchor is adapted to be retained within the esophagus, preferably just above the gastroesophageal (GE) Junction. The anchor can include a stent such as a wave anchor and is collapsible for catheter-based delivery and removal.Type: ApplicationFiled: February 21, 2008Publication date: August 28, 2008Applicant: GI Dynamics, Inc.Inventors: David A. Melanson, Manoel dos Passos Galvao Neto
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Publication number: 20080208355Abstract: A gastric implant system includes a gastric implant such as a restrictive pouch or a gastric balloon, an anchor passable through the mouth and stomach and further through the stomach wall into engageable with abdominal wall tissue. When the anchor is engaged to abdominal wall tissue, the stomach wall and abdominal wall are brought into contact with one another such that a proximal portion of the anchor extends into the stomach interior while a distal portion of the anchor remains engaged to the abdominal wall. A locking element coupled to the proximal section of the anchor is used to maintain contact between the stomach wall and abdominal wall. The gastric implant is advanced through the oral cavity into the stomach and is coupled to the anchor.Type: ApplicationFiled: September 14, 2007Publication date: August 28, 2008Inventors: Richard S. Stack, William L. Athas
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Publication number: 20080195225Abstract: A method for treating morbid obesity in a body of a mammal having a gastrointestinal tract extending through a stomach and a pyloric sphincter and a wall forming the stomach and pyloric sphincter. At least one implant is formed in the wall in the vicinity of the pyloric sphincter to inhibit emptying of the stomach.Type: ApplicationFiled: April 14, 2008Publication date: August 14, 2008Applicant: Scimed Life Systems, Inc.Inventors: David E. SILVERMAN, Alan Stein
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Publication number: 20080167614Abstract: Apparatus is provided, including a first rotating member configured to be implanted in an airway of a subject and rotated in an inhalation direction by an inhaled flow of fluid in the airway. A mechanical energy accumulator is configured to accumulate energy from the rotation of the first rotating member. Other embodiments are also described.Type: ApplicationFiled: January 8, 2008Publication date: July 10, 2008Inventors: David Tolkowsky, Aharon Shapira
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Publication number: 20080161935Abstract: A method for inducing weight loss in a patient by providing an implant for placement within the stomach. The implant having a member with an undeployed shape for delivery to the stomach and a deployed shape for implantation therein. The member has a plurality of links pivotably connected to each other, and a flexible elongated tether connected to the member. The method then involves delivering the member to the stomach while in its undeployed shape, and placing the member in its deployed shape by applying tension to the tether. The method also involves exerting an outward force against an interior of the stomach so as to bring together two substantially opposing surfaces of the hollow body by placing the member in its deployed position.Type: ApplicationFiled: March 14, 2008Publication date: July 3, 2008Inventors: Thomas E. Albrecht, Mark S. Zeiner
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Publication number: 20080109086Abstract: Expanding or foaming adhesives are used to reduce the stomach volume to reduce the caloric intake and weight of a patient. A web structure is attached inside the stomach and an expanding or foaming adhesive is applied to the web structure. The expanding or foaming adhesive attaches to the web structure and to the stomach to partition the stomach. The partition barrier divides the stomach volume into a reduced volume available for food storage and an empty volume that the food cannot enter. The reduced volume enables the patient to feel full faster and reduce caloric intake. A passageway can be provided between the two volumes near the base of the stomach to allow food or fluids to exit from the empty volume.Type: ApplicationFiled: November 8, 2006Publication date: May 8, 2008Inventors: James W. Voegele, Douglas J. Turner, Mark S. Ortiz, Frederick E. Shelton
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Publication number: 20080109087Abstract: The pyloric obesity valve includes a tubular valve body having proximal and distal ends. The valve body has an intermediate section which is between the proximal and distal ends. The proximal end is enlarged transversely relative to the intermediate section. The valve body has an inner surface and a lumen. The inner surface which is within the intermediate section has a cross-sectional area which is smaller than a cross-sectional area of the inner surface which coincides with the proximal end to resist a flow through the lumen of the valve body from the proximal end to the intermediate section.Type: ApplicationFiled: November 8, 2006Publication date: May 8, 2008Inventor: Russ Durgin
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Patent number: 7364591Abstract: A method for treating morbid obesity in a body of a mammal having a gastrointestinal tract extending through a stomach and a pyloric sphincter and a wall forming the stomach and pyloric sphincter. At least one implant is formed in the wall in the vicinity of the pyloric sphincter to inhibit emptying of the stomach.Type: GrantFiled: May 16, 2006Date of Patent: April 29, 2008Assignee: Scimed Life Systems, Inc.Inventors: David E. Silverman, Alan Stein
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Apparatus and method for treating obesity using neurotoxins in conjunction with bariatric procedures
Publication number: 20080092910Abstract: The present invention provides methods for facilitating weight loss in a patient. The methods of the present invention comprise the steps of administering a neurotoxin to a stomach tissue of an obese patient and performing one of several types of bariatric surgeries in the patient, thereby reducing or eliminating unwanted side effects, such as nausea and vomiting.Type: ApplicationFiled: October 18, 2006Publication date: April 24, 2008Inventor: Gregory F. Brooks -
Publication number: 20080097510Abstract: A method for inducing weight loss with a patient, using the step of providing an implant for placement within the stomach wherein the implant is a member having an undeployed shape for delivery to the stomach and a deployed shape for implantation therein. The method also involves the step of delivering the member to the stomach while in its undeployed shape. The method further involves the step of exerting an outward force against an interior of the stomach so as to bring together two substantially opposing surfaces of the hollow body by placing the member in its deployed position.Type: ApplicationFiled: September 1, 2006Publication date: April 24, 2008Inventors: Thomas E. Albrecht, Mark S. Ortiz, David N. Plescia, Michael J. Stokes, Katherine L. Youmans, James W. Voegele, Mark S. Zeiner, Jason L. Harris
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Patent number: 7354454Abstract: A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.Type: GrantFiled: July 16, 2004Date of Patent: April 8, 2008Assignee: Synecor, LLCInventors: Richard S. Stack, Richard A. Glenn, Trevor J. Moody, Fred E. Silverstein, Nathan Every, William S. Eubanks, Jr.
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Patent number: 7347875Abstract: Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal implant device is anchored in the stomach and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor for anchoring the device to the stomach and a flexible sleeve to limit absorption of nutrients in the duodenum. The anchor is collapsible for endoscopic delivery and removal.Type: GrantFiled: November 30, 2004Date of Patent: March 25, 2008Assignee: GI Dynamics, Inc.Inventors: Andy H. Levine, John Cvinar
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Patent number: 7320710Abstract: A urethral prosthesis with prostatic and bulbar segments connected by two types of ties allows the prosthesis to assume at least two configurations different with inter-segmental distances adapted to situations where the patient either has or does not have normal control of the external sphincter. This is particularly useful for a patient undergoing an anesthetic procedure that affects the external sphincter muscles. When the muscles are anesthetized, the prosthesis may provide constant urine voiding, and when the anesthetic effects wear off, the prosthesis may assume a different configuration to allow the sphincter to reassert control over urinary voiding.Type: GrantFiled: September 14, 2005Date of Patent: January 22, 2008Assignee: Boston Scientific Scimed, Inc.Inventors: Robert F. Rioux, Christopher R. O'Keefe
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Patent number: 7316716Abstract: A device (10) for treatment of obesity of a patient comprises an annular element (12) having a relatively large outer boundary and a relatively small inner boundary, and an elongated flexible tube (14) extending from the relatively small inner boundary of the annular element to a distal end. The relatively large outer boundary is adapted to be attached to an inner wall of a stomach (100) of a patient, such that the annular element divides the stomach (100) into two chambers, an esophagus-end chamber close to an esophagus of the patient, and a pylorus-end chamber close to a pylorus of the patient. The invention also provides a method for treatment of obesity of a patient which includes inserting an annular element having a relatively large outer boundary and a relatively small inner boundary into a stomach of the patient, and attaching the relatively large outer boundary of the annular element to an inner circumference of the stomach of the patient.Type: GrantFiled: May 9, 2003Date of Patent: January 8, 2008Assignee: Gastrix Medical, LLCInventor: Thomas D. Egan
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Patent number: 7314489Abstract: A method and apparatus to facilitate nutritional malabsorption by diverting digestive secretions, such as bile or pancreatic secretions. A tube is positioned substantially within the small intestine. The tube comprises a proximal end which when deployed is operative to receive digestive secretions, a distal end which when deployed is operative to discharge the digestive secretions into the alimentary tract, and a tube wall having an inner surface and an outer surface, the tube wall inner surface defining passage extending between the proximal and distal ends. When deployed the passage is operative to transfer the digestive secretions from the proximal end to the distal end thereby reducing digestive contact between the digestive secretions and food in the small intestine.Type: GrantFiled: August 20, 2003Date of Patent: January 1, 2008Assignee: Ethicon Endo-Surgery, Inc.Inventors: Robert Hugh McKenna, Jean Michael Beaupre
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Publication number: 20070282454Abstract: The anti-obesity diverter structure includes a laminate structure having papilla-supplied and pylorus-supplied surfaces. The laminate structure is sized to fit longitudinally within a duodenum such that a transverse clearance is provided between the papilla-supplied surface and papilla of Vater. The laminate structure is secured within the duodenum to define papilla-supplied and pylorus-supplied lumens therein. The papilla-supplied lumen receives the digestive fluid from the papilla of Vater, and provides a conduit for the digestive fluid therein. The pylorus-supplied lumen receives the chyme from the pylorus and provides a conduit for the chyme therein. The laminate structure is impervious or semi-permeable to the chyme and digestive fluid.Type: ApplicationFiled: May 30, 2006Publication date: December 6, 2007Inventors: Katie Krueger, Harold M. Martins
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Patent number: 7299805Abstract: An improved method of implanting cells in the body of a patient includes positioning viable cells on a support structure. One or more blood vessels may be connected with the support structure to provide a flow of blood through the support structure. A support structure may be positioned at any desired location in a patient's body. The support structure may be configured to replace an entire organ or a portion of an organ. An organ or portion of an organ may be removed from a body cells and/or other tissue is removed to leave a collagen matrix support structure having a configuration corresponding to the configuration of the organ or portion of an organ. Alternatively, a synthetic support structure may be formed. The synthetic support structure may have a configuration corresponding to a configuration of an entire organ or only a portion of an organ.Type: GrantFiled: June 6, 2003Date of Patent: November 27, 2007Assignee: MarcTec, LLCInventor: Peter M. Bonutti
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Patent number: 7291180Abstract: A medical stent is sized for placement in a ureter. The stent includes a first section which includes a first material, defines a lumen, and includes a first coil completing at least one revolution. A second section of the stent includes a second material, defines a lumen, and includes a second coil completing at least one revolution. A third section defines a lumen and is located between the first and second sections. The third section includes a co-extrusion of the first and second materials. One of the first or second sections is harder than the other section.Type: GrantFiled: January 27, 2004Date of Patent: November 6, 2007Assignee: Boston Scientific Scimed, Inc.Inventor: Ernest J. St. Pierre
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Patent number: 7267694Abstract: Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal implant device is anchored in the stomach and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor for anchoring the device to the stomach and a flexible sleeve to limit absorption of nutrients in the duodenum. The anchor is collapsible for endoscopic delivery and removal.Type: GrantFiled: November 30, 2004Date of Patent: September 11, 2007Assignee: GI Dynamics, Inc.Inventors: Andy H. Levine, John Cvinar, Dave Melanson, John C. Meade