Implantable Prosthesis Patents (Class 623/11.11)
  • Patent number: 10492899
    Abstract: A full-function artificial organ fitting body comprises a cortex layer and an organ body tissue area. The organ body tissue area comprises a growth area, a differentiation area, a docking area, a branch arterial system, a branch nervous system and a branch venous system. The branch arterial system, the branch nervous system and the branch venous system are distributed in the differentiation area and form a main body three-dimensional skeleton structure with the outer growth area and the middle docking area.
    Type: Grant
    Filed: September 4, 2017
    Date of Patent: December 3, 2019
    Inventor: Chang Liu
  • Patent number: 10485665
    Abstract: Apparatus and method for constructing a cartilage structure preferably has a first plate, and a blade mounted over the first plate. The blade preferably has (i) a predetermined shape, and (ii) a cutting edge protruding from the first plate and configured to cut a cartilage into the predetermined shape. A second plate preferably has a guide imprint adjacent a surface thereof, the guide imprint having a shape complimentary to the predetermined shape of the blade. A press preferably has (i) a first surface configured to mount the first plate, and (ii) a second surface configured to mount the second plate. Actuation structure is preferably configured to press together the press first and second surfaces to thereby cause the blade to cut the cartilage in the predetermined shape. The method utilizes similar structure to prepare at least two cartilages, which are joined together to form a three-dimensional cartilage structure.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: November 26, 2019
    Assignee: ReconstratA, LLC
    Inventors: Anirudh Arun, Angelo Alberto Leto Barone
  • Patent number: 10342663
    Abstract: Embodiments of the invention include a disc or vertebral defect packing tape for use in disc fusion, disc regeneration or for the creation of artificial disks. The tape comprises a tape body and one or more support members. Each of the support members is contained within the tape body and/or adhered to an external surface of the tape or tape body. The tape body is configured as a packing material and each of the support members is configured to hold the tape body together.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: July 9, 2019
    Assignee: Perumala Corporation
    Inventor: Madhavan Pisharodi
  • Patent number: 10179129
    Abstract: A method of treating or preventing capsular contracture in a patient resulting from surgical insertion of a silicone breast implant in a surgically created implant pocket. The method includes administering to the patient a therapeutically effective amount of a leukotriene receptor antagonist prior to the formation of a capsular contracture in the patient. The method further includes administering a therapeutically effective amount of displacement of the breast implant within the surgically created implant pocket, the therapeutically effective amount of displacement of the breast implant being administered post-surgically but prior to the formation of a capsular contracture in the patient.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: January 15, 2019
    Inventor: Stephen David Bresnick
  • Patent number: 10179180
    Abstract: The invention relates in various embodiments to a composite useful as e.g. a medical implant device, and a method of treating fouling, including biofouling as may occur on an implant. The composite comprises a matrix phase and a patterned phase that comprises an energetically activatable wire intermixed with the matrix phase, the wire when energetically activated, which includes thermal activation, causes modification of at least a portion of the matrix phase to treat fouling that might otherwise occur. The method of treating biofouling may be practiced on a patent while the medical implant of the invention is in situ.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: January 15, 2019
    Assignee: UT-BATTELLE, LLC
    Inventors: Steve L. Allman, Mitchel J Doktycz, Scott T Retterer, David P. Allison
  • Patent number: 10137014
    Abstract: A stent (32) configured to be placed in a body lumen and having a tubular shape formed by a structure that is expandable and contractible skeleton (18, 19) in a radial direction, the skeleton (18, 19) having a heteromorphic structure due to changes of a cross section shape thereof in a thickness direction. A stent (10) that is expandable and contractible in the radial direction while being configured to be placed in a body lumen, the stent (10) having a heteromorphic tubular shape, a cross section shape of which changes in a lengthwise direction, and having a metal skeleton (18, 19) formed by at least one of electroforming and etching.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: November 27, 2018
    Assignee: NIPRO Corporation
    Inventors: Yoshihiko Sano, Yasushi Ooyama, Katsuhiro Hiejima, Kouji Akimoto
  • Patent number: 10130737
    Abstract: The present invention provides tissues derived from animals, which lack any expression of functional alpha 1,3 galactosyltransferase (alpha-1,3-GT). Such tissues can be used in the field of xenotransplantation, such as orthopedic reconstruction and repair, skin repair and internal tissue repair or as medical devices.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: November 20, 2018
    Assignee: Revivicor, Inc.
    Inventors: David Ayares, Paul Rohricht
  • Patent number: 10098681
    Abstract: A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust the release of the substance. In various embodiments, the covering may be formed of a collagen material and is suitable for a variety of procedure specific uses.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: October 16, 2018
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Guobao Wei, Todd M. Boyce, Robert Cohen, Cristy Richards, Lawrence A. Shimp
  • Patent number: 10092409
    Abstract: A device and method of manufacturing and implanting a custom subtalar arthroereisis implant having side surfaces which are mirrored in topography with the sinus tarsi of a patient. The implant is formed using images of the patient standing in a weight bearing position with their sinus tarsi and the surrounding bone structure in an anatomically correct alignment. Once implanted, the implant urges and maintains the anatomically correct alignment thereby minimizing any patient tendency for abnormal motion between said patent's talus and calcaneus.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: October 9, 2018
    Inventor: Kent A. Feldman
  • Patent number: 10052186
    Abstract: A prosthetic implant includes an anterior surface, configured for at least partial contact with an underside of a patient's facial soft tissue. A posterior surface is oppositely placed to the anterior surface. The posterior surface is configured for at least partial contact with a patient's facial bony tissue when the anterior surface is in at least partial contact with the patient's facial soft tissue. An implant body is defined by the anterior and posterior surfaces and extends transversely therebetween. A selected portion of the posterior surface has a texture that mechanically differs from a texture of a majority of the anterior surface.
    Type: Grant
    Filed: October 9, 2014
    Date of Patent: August 21, 2018
    Inventors: Francis A. Papay, Jessie San, Nicholas T. Wilkins, Cameron J. Fordyce
  • Patent number: 10034373
    Abstract: An electronic device having a circuit board and a battery is disclosed. The circuit board may include a through hole and an electrical pad surrounding the through hole. In order to electrically couple the circuit board to the battery, and in particular, an electrode of the battery, a tab (or plaque) is placed between the electrical pad and the electrode. The tab electrically couples with the electrical pad by a soldering operation. To couple (electrically and mechanically) the tab with the electrode, a welding operation is used. The welding operation may include a laser weld providing thermal energy through a laser beam. In this regard, the laser beam passes through the through hole, thereby (partially) melting the tab and forming a weld between the tab and the electrode. Accordingly, the tab covers the through hole such that the tab is positioned to receive the laser beam.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: July 24, 2018
    Assignee: Apple Inc.
    Inventors: Charles W. Werley, Haran Balaram, Richard L. Winslow
  • Patent number: 9949742
    Abstract: The invention concerns an accessory for removing material, in particular a file (3) or a cutting block, for prosthesis implantation surgery, in particular for hip or knee prostheses. The invention is characterised in that it comprises at least partly one plastic part and at least one insert (4, 10, 5) made of a material harder than the bone material, in particular of metal, which is fixed to the plastic material such that if the device is brought to a temperature Ti, the insert is separated from the plastic material.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: April 24, 2018
    Inventor: Jean-Francois Biegun
  • Patent number: 9867686
    Abstract: The implantable hernia prosthesis of the present invention comprises at least one piece of mesh (1) arranged to cover at least a portion of the hernia, at least one support element (2) attached to said piece of mesh (1), said support element (2) comprising at least one resilient, deformable biasing filament, characterized by said support element (2) being an uninterrupted tension providing ring surrounding a portion of said mesh (1) and further comprising an indentation directed towards the center of said ring.
    Type: Grant
    Filed: September 25, 2012
    Date of Patent: January 16, 2018
    Assignee: Bard Shannon Limited
    Inventors: Rui Manuel De Melo Soares Da Costa, Augusto Manuel De Almeida Lourenço
  • Patent number: 9848994
    Abstract: The present application generally relates to orthopedic systems, and in particular, to systems including independent plates and spacers. A plating system can include a spacer and a plate that is independent from the spacer. A number of locking mechanisms can be provided to secure the plate to the spacer. In some cases, the spacer includes a pair of notches that extend on an outer surface of the spacer. The plate can include a pair of lateral extensions that can engage the notches to secure the plate to the spacer. In other cases, the spacer includes an opening including a pair of inlets. The plate can include an enclosed posterior extension that can be received in the pair of inlets to secure the plate to the spacer.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: December 26, 2017
    Assignee: GLOBUS MEDICAL, INC.
    Inventors: Samuel Petersheim, Jason Cianfrani, Aditya Ingalhalikar, Jennifer Klimek, Jason Gray
  • Patent number: 9808616
    Abstract: The present disclosure provides a regenerative peripheral nerve interface (RPNI) for a subject comprising an insulating substrate, at least one metallic electrode deposited onto the insulating substrate forming a thin-film array; a portion of the at least one metallic electrode surface having a layer of a first conductive polymer and a layer of decellularized small intestinal submucosa (SIS) coating a portion of the electrode, wherein a second conductive polymer is electrochemically polymerized through the SIS to form the regenerative peripheral nerve interface. The present disclosure also provides that a layer of muscle tissue contacts the regenerative peripheral nerve interface.
    Type: Grant
    Filed: January 13, 2012
    Date of Patent: November 7, 2017
    Inventors: Paul S. Cederna, Melanie G. Urbanchek, David C. Martin
  • Patent number: 9789458
    Abstract: The invention provides a method for increasing the order of an array of polymeric micelles or of nanoparticles on a substrate surface comprising a) providing an ordered array of micelles or nanoparticles coated with a polymer shell on a substrate surface and b) annealing the array of micelles or nanoparticles by ultrasonication in a liquid medium which is selected from the group comprising H2O, a polar organic solvent and a mixture of H2O and a polar organic solvent. In a related aspect, the invention provides the highly ordered arrays of micelles or nanoparticles obtainable by the methods of the invention.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: October 17, 2017
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Christian Williges, Christoph Morhard, Joachim P. Spatz, Robert Brunner
  • Patent number: 9782515
    Abstract: A method for treating an oral condition of a subject by grafting cultured tissue constructs to the oral tissue. The cultured tissue constructs comprise cultured cells and endogenously produced extracellular matrix components without the requirement of exogenous matrix components or network support or scaffold members. Some tissue constructs of the invention are comprised of multiple cell layers or more than one cell type. The tissue constructs of the invention have morphological features and functions similar to tissues their cells are derived and their strength makes them easily handleable. Preferred cultured tissue constructs of the invention comprise cells derived from human tissue.
    Type: Grant
    Filed: March 5, 2007
    Date of Patent: October 10, 2017
    Assignee: Organogenesis, Inc.
    Inventor: Dario C. Eklund
  • Patent number: 9713524
    Abstract: Human implantable tissue expanders are provided, that comprise an inner foam filling enclosed within a substantially non-stretchable resilient expansion restricting layer configured to retain a shape and/or volume of said foam filling upon changes of ambient pressure and/or temperature, and an outer shell comprising one or more layers formed of a resilient material.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: July 25, 2017
    Assignee: IMPLITE LTD.
    Inventor: Ami Glicksman
  • Patent number: 9687332
    Abstract: A method and device for treating hernia by implanting at least one collapsible hernia repair patch, such as a planar mesh body at least partially enveloped by one or more elastic collars. A posterior end of an applicator carrying the repair patch may be inserted through a hernia and into the wall of the abdominal cavity, and the patch may be released into the cavity, e.g., so as to helically deploy the patch such that the patch lies in parallel to the abdominal wall. A balloon, which is removably attached to the patch, may be inflated to help move the patch to a deployed configuration, and thereafter the balloon removed from the hernia site.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: June 27, 2017
    Assignee: Davol, Inc.
    Inventors: Mordehai Sholev, Ibrahim Matter, Ziv Tamir
  • Patent number: 9687347
    Abstract: A percutaneous implant (10) comprises a bone-fixation portion (20), a spigot portion (50) for the attachment of an external prosthesis, and a pear-shaped portion (40) having a porous outer region (44) comprising a mesh of wire mesh material around a central core. The portion (40) is disposed between the spigot portion (50) and a collar (30) which has a plurality of through holes (34) adjacent to its edge. The bone-fixation portion (20) may have extending parallel thereto a plate (72) for attachment to the side of a bone.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: June 27, 2017
    Inventor: Martin Noel Fitzpatrick
  • Patent number: 9659152
    Abstract: A technique for generating a data set that geometrically defines a bone cut configuration for transverse maxillary distraction is using a computer-implemented method. An aspect of the technique comprises creating a numeric model of a maxilla based on patient-specific data of the maxilla. The numeric model is representative of mechanical properties of the maxilla. Based on the numeric model thus generated, one or more cut configurations for one or more bone cuts on at least one of a left hand side and a right hand side of the maxilla are determined. Each cut configuration has been determined to compensate for asymmetric mechanical properties of the maxilla. In a further step, a data set indicative of the one or more cut configurations thus determined is generated. The data set may be used to create a surgical template or jig, for computer-assisted surgery or a surgical navigation system.
    Type: Grant
    Filed: April 10, 2014
    Date of Patent: May 23, 2017
    Inventor: Christoph Mueller
  • Patent number: 9636438
    Abstract: The present invention relates to a temporary composite scaffold comprising discrete ECM particles formed as a fistula plug. We demonstrate that when using scaffolds containing ECM material, higher concentrations of ECM surprisingly do not give better cell morphology. Concentrations lower than 60% (w/w) are sufficient to obtain the best cell morphology and distribution.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: May 2, 2017
    Assignee: Coloplast A/S
    Inventors: Lene Feldskov Nielsen, Jens Hoeg Truelsen, Hanne Everland
  • Patent number: 9629946
    Abstract: A polymeric product including at least two layers, wherein a functional layer includes a polymeric material and at least one anti-microbial substance, and a protective layer, including a polymeric material arranged outside the functional layer and completely covering the functional layer, wherein the protective layer does not include any anti-microbial substances. A method of producing the product, the use of the same and a kit for producing the product.
    Type: Grant
    Filed: September 13, 2011
    Date of Patent: April 25, 2017
    Assignee: NANEXA AB
    Inventors: Anders Johansson, Marten Rooth
  • Patent number: 9605349
    Abstract: Methods of manufacturing produce metal implants having nano-modified surfaces that contain antimicrobial properties. The methods may include immersing the implant in an acid, rinsing the acid-treated implant in an aqueous cleaner, and thereafter heating the rinsed implant. The nano-modified implants described herein may contain an increased surface roughness; surface features with increased width or height; and/or decreased surface energy. The implants that result from these methods contain a nano-modified surface that is resistant to microbial cell adhesion and ultimately reduce biomaterials-related infections at the implant site.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: March 28, 2017
    Assignee: Howmedica Osteonics Corp.
    Inventors: Thomas J. Webster, Godofredo R. Dimaano, Kevor Shane Tenhuisen, Gene Kulesha, John Muth
  • Patent number: 9566168
    Abstract: The present invention provides an expandable fusion device capable of being installed inside an intervertebral disc space to maintain normal disc spacing and restore spinal stability, thereby facilitating an intervertebral fusion. In an exemplary embodiment, the present invention provides an intervertebral implant. The intervertebral implant may be configured to transition from a collapsed configuration having a first height and a first width to an expanded configuration having a second height and a second width.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: February 14, 2017
    Assignee: GLOBUS MEDICAL, INC.
    Inventors: Chad Glerum, Andrew Iott, Mark Adams
  • Patent number: 9566169
    Abstract: Structural allograft fusion devices containing a single integral piece of cortical bone in combination with one or more pieces of cancellous bone, wherein the cortical and cancellous pieces are pinned together.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: February 14, 2017
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Michael Mazzuca, Thomas Gamache
  • Patent number: 9554725
    Abstract: Embodiments relate to a method of monitoring physiological parameters of a patient with renal dysfunction. The method includes electrically connecting one or more medical device electrodes with a measurement site of a patient, generating one or more first stimulation signals sufficient to provide input physiological parameters specific to the patient, measuring one or more first bioimpedance values from the generated signals, analyzing at least one of the input physiological parameters within the one or more first bioimpedance values and generating a personalized dialysis program. The systems and methods can further provide essentially real-time data of patient undergoing treatment and control of treatment to a patient.
    Type: Grant
    Filed: September 9, 2010
    Date of Patent: January 31, 2017
    Assignee: Medtronic Monitoring, Inc.
    Inventors: Rodolphe Katra, Niranjan Chakravarthy, Imad Libbus
  • Patent number: 9545321
    Abstract: This specification describes technologies relating to an intervertebral disc prosthesis used to strengthen and stabilize the spine. Implementations of the technology described herein comprise a surgical device that is implanted through a small surgical incision into a portion of a human intervertebral disc, various support tools used to insert such a surgical device, and a method by which the device is used to strengthen and stabilize the spine.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: January 17, 2017
    Inventors: Nadi Salah Hibri, James Douglas Lutz
  • Patent number: 9498626
    Abstract: A system and method of generating electrode stimulation signals for electrode contacts in an electrode array associated with a hearing implant is presented. An input audio signal is processed to generate a plurality of band pass channel signals each representing an associated band of audio frequencies. A stationary noise reduction is applied so as to provide a stationary noise reduced channel envelope from each channel signal. A transient in one or more of the channel envelopes is detected. The channel envelopes are modified as a function of whether the transient is transient noise or transient speech, so as to form transient modified envelope. The transient modified envelopes are used to generate electrode stimulation signals to the electrode contacts.
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: November 22, 2016
    Assignee: MED-EL Elektromedizinische Geraete GmbH
    Inventors: Florian Frühauf, Ernst Aschbacher
  • Patent number: 9492588
    Abstract: A calcium phosphate/copper coating for an implant is provided which includes highly porous calcium phosphate and predominantly discontinuously distributed copper. The highly porous calcium phosphate first forms a highly porous calcium phosphate layer in which the copper has been incorporated so as to be discontinuously distributed, to form the calcium phosphate/copper coating. Further provided are a method of producing such a calcium phosphate/copper coating and an implant coated therewith.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: November 15, 2016
    Assignee: DOT GMBH
    Inventors: Hans-Georg Neumann, Cornelia Prinz
  • Patent number: 9474559
    Abstract: A bone anchor compatible for use with a neural integrity monitoring systems includes a bone-engaging portion extending between a first end portion and a second end portion. The first end portion includes a resorbable non-electrically conductive polymer defining an insulated region. The second end portion includes a conductive region having reduced electrical resistance relative to the insulated region. The insulated region is contiguous with the conductive region. Methods of use are disclosed.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: October 25, 2016
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Hai H Trieu, Matthew Morrison
  • Patent number: 9457133
    Abstract: An implant comprises a structure that may be implanted into tissue and that has a first material property at normal body temperature. The first material property is variable at elevated temperatures above normal body temperature. The implant also has a plurality of particles dispersed in the structure that are adapted to convert incident radiation into heat energy when irradiated with electromagnetic radiation. The particles are in thermal contact with the structure such that exposure of the particles to incident radiation raises the temperature of the structure thereby changing the first material property relative to the first material property at normal body temperature.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: October 4, 2016
    Assignee: J.W. Medical Systems Ltd.
    Inventors: Patrick H. Ruane, Cameron L. Wilson
  • Patent number: 9452064
    Abstract: The invention relates to a spinal implant composed of a plurality of parallel plates. The deliberate introduction of contours in the plates allows for the creation of biomechanically advantageous functions and adjustment options. The elasticity of the anchoring elements enables the disclosed implant to be adjusted to the osseous endplates, resulting in uniform force distribution and thus prevention of the risk of compaction or endplate compression fracture. The plate structure allows for the use of production methods in which hook-like undercut contours can be created, thus enabling the implant to be superbly anchored in the bone without causing damage thereto. Furthermore, the plates can be interconnected by an actuator in such a way that the height and/or the angular position can be adjusted. The vertical adjustment can vary along the length of the implant such that the segment can also be angularly adjusted.
    Type: Grant
    Filed: October 5, 2011
    Date of Patent: September 27, 2016
    Inventors: Frank Trautwein, Frank Heuer, Jorg Franke, Ralph Kothe, Ulf Liljenqvist, Guy Matge, Michael Putzier
  • Patent number: 9447304
    Abstract: Coatings for a surface, especially a priming coating, of the present invention have been found to be durable, resistant to oxidative degradation, erosion and depolymerization, stable to sterilization and low particulating, and are easily applied to the required surface of a substrate in a surface-independent manner. Such coatings, when used as priming coatings to be coated with a subsequent coating, in at least some embodiments, form exterior coatings which are also highly durable and are stable to sterilization and aging.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: September 20, 2016
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Paul D. Drumheller, Charles D. Claude
  • Patent number: 9439790
    Abstract: An intraluminal prosthesis includes an outer three-dimensional (3D) anti-migration structure that is attached to the outer wall of a fully covered or partially covered stent to prevent migration and still allow stent removal at a later period of time. A method of manufacturing the intraluminal prosthesis includes attaching the anti-migration structure by usage of a polymer such as polyurethane.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: September 13, 2016
    Inventors: Claude Clerc, Sri Tupil
  • Patent number: 9414867
    Abstract: The present application is directed to devices and methods for treating vertebral fractures with one or more bone pins. In one embodiment of a method, a fractured vertebral body may he accessed through a pedicle portion and an opening may be created therethrough. One or more bone pins may be inserted through the opening. In one embodiment, at least one of the inserted bone pins is inserted to extend across a fracture zone with a proximal portion of the pin engaging a first bone segment and a distal portion engaging a second bone segment. The pin or pins may be manipulated to immobilize the first and second portions of the fractured vertebra.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: August 16, 2016
    Assignee: GLOBUS MEDICAL, INC.
    Inventors: David C. Paul, Sean Suh
  • Patent number: 9414905
    Abstract: A muscle prosthesis with a suspension fixing apparatus for implantation into a human body and production method thereof; the muscle prosthesis comprises a muscle prosthesis main body and the suspension fixing apparatus; the suspension fixing apparatus consists of at least one stretchable part and at least two fasteners; the suspension fixing apparatus can fix the muscle prosthesis to a human bone or human muscle tendon and fascia. The suspension fixing system can change the thickness and outer shape of the prosthesis according to the direction and intensity of a tensile force, thus satisfying the requirements of different body parts and different muscle thicknesses. Use of the suspension fixing apparatus allows the prosthesis to be fixed firmly and be structurally stable, thus solving the technical problem of drooping and shifting prostheses.
    Type: Grant
    Filed: January 16, 2012
    Date of Patent: August 16, 2016
    Inventor: Jiangning Wang
  • Patent number: 9399091
    Abstract: A medical device system including a physiological sensor and ultrafiltration unit senses a physiological signal in a patient and computes a fluid status measurement of the patient using the physiological signal. Ultrafiltration therapy is delivered to the patient according to a therapy delivery control parameter established in response to the fluid status measurement.
    Type: Grant
    Filed: September 30, 2009
    Date of Patent: July 26, 2016
    Assignee: Medtronic, Inc.
    Inventors: Daniel C. Sigg, Sarah Anne Audet, Tommy D. Bennett, Dwight H. Warkentin
  • Patent number: 9393195
    Abstract: Neo-cartilage constructs suitable for implantation into a joint cartilage lesion in situ and a method for repair and restoration of function of injured, traumatized, aged or diseased cartilage. The construct comprises at least chondrocytes incorporated into a support matrix processed according to the algorithm comprising variable hydrostatic or atmospheric pressure or non-pressure conditions, variable rate of perfusion, variable medium composition, variable temperature, variable cell density and variable time to which the chondrocytes are subjected.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: July 19, 2016
    Assignee: Histogenics Corporation
    Inventors: Shuichi Mizuno, Akihiko Kusanagi, Laurence J. B. Tarrant, Toshimasa Tokuno, Robert Lane Smith
  • Patent number: 9364309
    Abstract: According to an aspect of the present invention, surgical films for soft tissue repair are provided. The surgical films comprise at least one sheet of a non-filamentous material within which pores are formed. Further aspects of the invention, among others, pertain to methods of using such surgical films and to kits containing such surgical films.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: June 14, 2016
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Jianmin Li, James Goddard, Timothy P. Harrah, Doreen Rao, Alfred Intoccia, Leo James Lichte
  • Patent number: 9352146
    Abstract: The present disclosure provides nerve interface devices, such as passive or active nerve caps or regenerative peripheral nerve interface devices (RPNI), for a subject in need thereof. The nerve interface devices include nerve interface cap devices capable of treating, minimizing, or preventing formation of neuromas in severed or damaged nerve endings. Such a nerve interface device includes a housing that may be formed of a scaffold, such as a biotic material or hydrogel, an autograft, and optionally an electrode and/or conducting polymer. The autograft may be free muscle or free skin tissue, which is attached to the nerve ending to permit reinnervation. The present disclosure also provides methods for treating, minimizing, or preventing neuroma formation in a subject having a severed or damaged nerve, especially a peripheral nerve.
    Type: Grant
    Filed: July 17, 2013
    Date of Patent: May 31, 2016
    Assignee: The Regents Of The University Of Michigan
    Inventors: Nicholas B. Langhals, Paul S. Cederna, Melanie G. Urbanchek
  • Patent number: 9333062
    Abstract: A bodily implant is provided that includes a support member and an arm member. The support member is configured to be placed within a body of a patient such that the support member surrounds a rectum of the patient. The arm member extends from the support member and is configured to be coupled to a portion of the body of the patient to help retain the support member in place within the body of the patient.
    Type: Grant
    Filed: June 5, 2012
    Date of Patent: May 10, 2016
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: Jianmin Li
  • Patent number: 9326858
    Abstract: An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves. Cable allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. In addition, selective placement of point-welds or other such control points locally control other parameters such as the amount and direction of displacement as the ring undergoes external loading. Cable with well-placed control points result in a MIS annuloplasty ring with sufficient flexibility in the x-y plane to allow a surgeon to squeeze the ring into a small incision, such as for example 1 cm×1 cm, while maintaining structural rigidity under forces exerted on the implanted ring by the cardiac cycle and allowing for asymmetrical deflection to be designed into the product.
    Type: Grant
    Filed: February 5, 2013
    Date of Patent: May 3, 2016
    Assignee: Edwards Lifesciences Corporation
    Inventors: John F. Migliazza, Bob Crockett, Tim Abram
  • Patent number: 9314944
    Abstract: A tissue displacement/separation device is provided. The device includes a bladder which is expandable between a first tissue and a second tissue of a body. The bladder has an expanded shape which is selected capable of displacing or separating the first tissue from the second tissue in a manner suitable for protecting the first tissue from an effect of a treatment applied to the second tissue.
    Type: Grant
    Filed: June 13, 2012
    Date of Patent: April 19, 2016
    Assignee: BIOPROTECT LTD.
    Inventors: Shaul Shohat, Abraham Jackob Domb, Adrian Paz
  • Patent number: 9308090
    Abstract: The present disclosure relates, at least in part, to a surgical implant and a method for manufacturing the surgical implant. In one embodiment, the surgical implant comprises a metallic substrate; a tantalum interlayer disposed adjacent to the metallic substrate and comprising ?-tantalum and amorphous tantalum; at least one DLC layer disposed adjacent the tantalum interlayer; wherein the amorphous tantalum has a phase gradient increasing from the metallic substrate side to the DLC side; wherein the DLC layer has a hardness value and an elastic modulus value; and wherein the hardness value has a gradient increasing away from the tantalum side; and wherein the elastic modulus value has a gradient from the tantalum side.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: April 12, 2016
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Kerstin Thorwarth, Roland Hauert, Gotz Thorwarth
  • Patent number: 9302103
    Abstract: A method improving or restoring neural function in a mammalian subject in need thereof, the method including: using an input receiver to record an input signal generated by a first set of nerve cells; using an a encoder unit including a set of encoders to generate a set of coded outputs in response to the input signal; using the encoded outputs to drive an output generator; and using an output generator to activate a second set of nerve cells wherein the second set of nerve cells is separated from the first set of nerve cells by impaired set of signaling cells. In some embodiments, the second set of nerve cells produces a response that is substantially the same as the response in an unimpaired subject.
    Type: Grant
    Filed: September 12, 2011
    Date of Patent: April 5, 2016
    Assignee: Cornell University
    Inventor: Sheila Nirenberg
  • Patent number: 9283309
    Abstract: A device for supplying energy to hydraulically or pneumatically actuated active implants. The device can take the form of pumping systems, metering systems, and/or occlusion systems. The device comprises a receiving coil for generating an electric voltage due to a changing magnetic flux that is generated by an extracorporeal transmitting coil. The receiving coil is designed such that said coil can be implanted into subcutaneous tissue. Furthermore, an electric line is provided for transmitting the electric current that is generated by the receiving coil from the receiving coil to the active implant. The device further comprises a compensation container for temporarily receiving a transmitter fluid, by means of which the active implant is activated. The compensating container is mounted on the receiving coil and/or on the electric line such that the compensating container together with the receiving coil and/or the electric line can be implanted into a common tissue or muscle pocket in the body of a patient.
    Type: Grant
    Filed: March 18, 2011
    Date of Patent: March 15, 2016
    Assignee: Deutsches Zentrum Fuer Luft-Und Raumfahrt E.V.
    Inventors: Thomas Schmid, Bernhard Vodermayer, Cornelia Riecke, Annika Rybak, Matthias Grzeski
  • Patent number: 9259435
    Abstract: Materials capable of delivering stabilized free radicals to targeted treatment sites. The materials comprise semi-crystalline, hydrolytically degradable polymers that are subjected to ionizing radiation to create stabilized free radicals therein. Upon exposure to oxygen containing aqueous media, the materials generate reactive oxidative species which are useful in biological processes.
    Type: Grant
    Filed: August 29, 2013
    Date of Patent: February 16, 2016
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Tiffany J. Brown, Adam S. Lafleur, Kenneth Mazich, Jeffrey C. Towler, Ji Zhang
  • Patent number: 9248011
    Abstract: A method of treating a vaginal prolapse is provided. The method includes accessing a vaginal prolapse, inserting an implant comprising a knitted mesh into a patient, and securing the knitted mesh in place such that the implant supports the pelvic floor of the patient. The knitted mesh has a mass density of less than 20 g/m2.
    Type: Grant
    Filed: December 11, 2011
    Date of Patent: February 2, 2016
    Assignee: Coloplast A/S
    Inventor: James Browning
  • Patent number: 9247910
    Abstract: An implant system and a method for controlling the natural and artificial microenvironments surrounding an implanted device using an artificial tissue system (ATS) and includes methods of diagnostic and testing related thereto. The ATS, among other things, induce better integration, function, and extended lifespan of the devices at the site of implantation. The ATS includes cells, such as naturally occurring, engineered, and/or artificial cells; matrices such as natural, engineered, artificial and/or hybrid matrices; tissue response modifiers (TRM); and/or cell response modifiers (CRM). The specific composition of the ATS is based on the nature of the tissue in which ATS-device combination is implanted and the nature of the implant device, as well as the required function and lifespan of the implanted device. Additionally, the ATS, as well as ATS-device combinations can be utilized in vitro to aid in the design of improved ATS, devices and ATS-device combinations for in vivo uses.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: February 2, 2016
    Assignee: University of Connecticut
    Inventors: Ulrike W Klueh, David I Dorsky, Donald L Kreutzer