Implantable Prosthesis Patents (Class 623/11.11)
  • Patent number: 11357975
    Abstract: A cylindrical microelectrode array having an elongated cylindrical core, and a multilayer structure conformally folded around and affixed to the cylindrical core so as to extend between opposite ends of the core. The multilayer structure has integrated sections including an electrode section with electrodes exposed through electrically insulating layers, a connector section with conductive bond pads for interfacing with external electronics, and a cable section with conductive traces encapsulated in electrically insulating layers and which connect between the electrodes and their corresponding bond pads. The array may be fabricated using a planar multilayer structure having the electrode, connector, and cable sections, and conformally folding the multilayer structure around and affixing to the cylindrical core. The cable section in particular may be conformally coiled around and affixed to the cylindrical core so that the electrical conduits helically extend between the connector and electrode sections.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: June 14, 2022
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Kedar G. Shah, Supin Chen, Sarah H. Felix, Satinderpall S. Pannu, Susant Patra, Vanessa Tolosa, Angela C. Tooker, Jason Jones
  • Patent number: 11280006
    Abstract: The present invention provides a method for preparing an implant including preparing a mixed etching composition including hydrogen peroxide and a water-soluble carbonate compound and oxidatively etching an implant made of titanium or a titanium alloy by immersing the same in the etching composition; a titanium or titanium alloy implant prepared by oxidative etching with a mixed etching composition including hydrogen peroxide and a water-soluble carbonate compound; and a composition for treating surface of an implant containing hydrogen peroxide and a water-soluble carbonate compound. Further, the present invention relates to a titanium or titanium alloy implant which is prepared by oxidative etching with a mixed etching composition including hydrogen peroxide and a basic solution and on which surface bumps having continuous or discontinuous line-shaped open channel structures in nanoscale are irregularly formed, and a preparation method thereof.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: March 22, 2022
    Assignee: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Kyo Han Kim, Tae Yub Kwon, Jun Sik Son
  • Patent number: 11266450
    Abstract: The invention relates to an arthrodesis plate for the stiffening of joints, in particular finger joints, comprising a proximal and distal anchoring region which are connected to one another in a mechanically rigid manner, characterised in that at least one outer contour of one of the two anchoring regions has a cross-section which is undulating, for example roof-shaped, or is provided with alternating crests and troughs by means of coating, and/or has a transversal-sagittal cross-section.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: March 8, 2022
    Assignee: WALDEMAR LINK GmbH & Co. KG
    Inventors: Helmut D. Link, Jan Teuber
  • Patent number: 11248304
    Abstract: A method for producing a transparent electrode for oxygen production having a Ta nitride layer on a transparent substrate, including: a step of forming a Ta nitride precursor layer on the transparent substrate; and a step of nitriding the Ta nitride precursor layer with a mixed gas containing ammonia and a carrier gas.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: February 15, 2022
    Assignees: Mitsubishi Chemical Corporation, THE UNIVERSITY OF TOKYO, JAPAN TECHNOLOGICAL RESEARCH ASSOCIATION OF ARTIFICIAL PHOTOSYNTHETIC CHEMICAL PROCESS, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Hiroshi Nishiyama, Tomohiro Higashi, Yutaka Sasaki, Taro Yamada, Kazunari Domen, Yohichi Suzuki, Seiji Akiyama
  • Patent number: 11246497
    Abstract: The disclosure relates to a method and system for processing a heart sensor output, wherein a blood flow and a simulated aortic blood pressure are derived from a sensed blood pressure using an arterial flow model and values for arterial flow parameters. The simulated aortic blood pressure is matched to a part of the sensed blood pressure in the cardiac cycle by manipulating at least one of the values for the arterial flow parameters of the arterial flow model.
    Type: Grant
    Filed: June 4, 2015
    Date of Patent: February 15, 2022
    Inventors: Jozef Reinier Cornelis Jansen, Johannes Jacobus Schreuder
  • Patent number: 11234827
    Abstract: A medical grade thermoplastic or polymer implant with an osteoconductive coating is provided, specifically for corrections of the distal and proximal interphalangeal toe joints of the foot. The implant can be either straight or angled, and can be either solid or cannulated for insertion. The implant is sized and shaped depending on the specific anatomy and desired correction. End portions of the implant may be coated with an osteoconductive coating that promotes bone growth, but may reduce radiolucency. Thus, a central portion of the implant may remain uncoated to increase radiolucency of the implant at the region where two bones come together.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: February 1, 2022
    Assignee: TRIDENT ORTHOPEDICS, INC.
    Inventors: Albert Eugene Austin, Steven K. Neufeld, Adam D. McQueen, Simon J. Mest, Paul S. Cooper
  • Patent number: 11197749
    Abstract: A fabric or mesh construct, and process for making same, which allows for early wound stability and then transitions to a more compliant state exhibiting a substantially constant macro-porous pore structure through the life of the implant to promote good tissue incorporation without bridging.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: December 14, 2021
    Assignee: POLY-MED, INC.
    Inventors: Michael Scott Taylor, Seth Dylan McCullen, Kenneth W. Clinkscales, Georgios T. Hilas
  • Patent number: 11160900
    Abstract: The invention is directed to a biodegradable tissue-adhesive device for sealing tissue, said device comprising a tissue-adhesive layer which comprises a blend of a tissue-reactive polymer and a biodegradable carrier polyurethane according to the formula of A-B-C-Bn, wherein A denotes a polyol, B denotes a diisocyanate moiety, C denotes a diol component and n denotes the number of recurring units, and wherein the B-C-B segment is bioresorbable.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: November 2, 2021
    Assignee: Polyganics IP B.V.
    Inventors: Martin Franke Tooren, Justin Van Der Veen, Dirk Erik Muller, Don Theo Hertsig, Harmen Hendrikus de Vries, Romke Stephan Rudolf Ribbels
  • Patent number: 11154704
    Abstract: A system for drawing blood from a heart of a patient, includes a blood pump, an outflow cannula and a flexible cannula assembly. The cannula assembly further includes a flexible cannula body including a proximal end, a distal end, an inner wall defining a lumen, and an outer wall. A tip is coupled with the distal end of the cannula body, and an anchor is coupled to the tip. The anchor is configured to engage an internal structure of the heart and resists movement of the cannula assembly in at least one direction along the flexible cannula body. A ring member is configured to be coupled to the heart wall and is positioned at least partially around the outer wall of the cannula body proximally relative to the tip. The ring member is further configured to provide hemostasis between the heart wall and the cannula body.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: October 26, 2021
    Assignee: CircuLite, Inc.
    Inventors: Robert C. Farnan, Robert G. Hudgins, John Dockter
  • Patent number: 11129701
    Abstract: The embodied invention is a lip implant that includes small eyelets on either end of a small diameter rod located inside, and extends beyond, the cosmetic volume of the implant. Sutures connected to eyelets on the rod ends, allow the implant to be pulled into a minimal lip cavity that is created for the implant. The implant is readily positioned by using the sutures. Only two small incisions are needed as well as the creation of a small cavity needed for the implant. The use of the embodied invention is also extended to vein implants to enhance the appearance of veins on arms, legs, or to other surfaces.
    Type: Grant
    Filed: March 11, 2021
    Date of Patent: September 28, 2021
    Inventor: Steve A. Haworth
  • Patent number: 11123903
    Abstract: A method for manufacturing a breast implant includes producing an elastic filler material including foam, by applying a source of gas bubbles to a silicone monomer to create a mixture. The mixture is inserted into a sealed chamber. After inserting the mixture, a pressure inside the sealed chamber is set to a first pressure, and a temperature of the mixture inside the sealed chamber is set to a first temperature. Then, following a preset time duration, the pressure is lowered to a second pressure that is lower than the first pressure, and after a given time, the temperature is lowered to a second temperature that is lower than the first temperature. A flexible shell, configured for implantation within a breast of a human subject, is filled with the elastic filler material.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: September 21, 2021
    Assignee: BIOSENSE WEBSTER (ISRAEL) LTD.
    Inventors: Yehuda Algawi, Assaf Govari
  • Patent number: 11116533
    Abstract: A medical manipulator is disclosed, which includes a multiple-degree freedom arm, which can be mounted with a medical instrument; a memory configured to retain an insertion port position indicating a spatial position of an insertion port for inserting the medical instrument mounted in the multiple-degree freedom arm into a human body; and a controller configured to determine an insertion posture of the medical instrument so as to cause an extended line of a major axis of the medical instrument to pass through the spatial position indicated by the insertion port position, and configured to move the multiple-degree freedom arm to the determined insertion posture.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: September 14, 2021
    Assignee: MEDICAROID CORPORATION
    Inventors: Makoto Jinno, Hiroaki Sano
  • Patent number: 11110204
    Abstract: A method of producing a bioabsorbable membrane includes: forming a liquid membrane by spin-coating a coating liquid containing a first bioabsorbable polymer and a solvent; and forming a dense layer by causing a porous membrane containing a second bioabsorbable polymer to contact the liquid membrane.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: September 7, 2021
    Assignee: GC Corporation
    Inventors: Yuuhiro Sakai, Yusuke Shigemitsu, Kyohei Toyonaga, Hidetoshi Funabashi
  • Patent number: 11109939
    Abstract: An intravascular treatment device is presented having an expandable frame made up of circular struts, straight struts, and bent struts forming a frame with circumference that varies over the length of the frame. Radiopaque markers can be positioned on the bent struts to indicate outer circumferences of the frame along the length of the frame. The device can be a stent or a clot retriever. If the device is a clot retriever, the proximal end of the expandable frame can be attached to a guide wire and the distal end of the expandable frame can be free to slide over the guide wire when the frame moves from a collapsed state to an expanded state and vice versa.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: September 7, 2021
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventor: Juan Lorenzo
  • Patent number: 11108284
    Abstract: A wireless power transmitting device is provided. The wireless power transmitting device may comprise an antenna, a memory, and a processor configured to control to store, as reference information, information of a first reflected signal of a pilot signal sent out through the antenna at a first time in the memory and control to compare the reference information with information about second reflected signals of a pilot signal sent out through the antenna at a second time, and determine a position of a target for detection based on a result of the comparison.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: August 31, 2021
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Chong-Min Lee, Kyung-Woo Lee, Sung-Bum Park, Jae-Hyun Park, Jae-Hyuck Shin, Young-Ho Ryu, Sang-Wook Lee
  • Patent number: 11071617
    Abstract: A multi-laminar electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a first layer formed by a first plurality of electrospun polymeric fibers, and a second layer formed by a second plurality of electrospun polymeric fibers. The second layer is combined with the first layer. A first portion of the scaffold includes a higher density of fibers than a second portion of the scaffold, and the first portion has a higher tensile strength than the second portion. The scaffold is configured to degrade via hydrolysis after at least one of a predetermined time or an environmental condition. The scaffold is configured to be applied to the tissue substrate containing the defect, and is sufficiently flexible to facilitate application of the scaffold to uneven surfaces of the tissue substrate, and to enable movement of the scaffold by the tissue substrate.
    Type: Grant
    Filed: October 6, 2020
    Date of Patent: July 27, 2021
    Assignee: Washington University
    Inventors: Matthew R. MacEwan, Jingwei Xie, Zack Ray, Younan Xia
  • Patent number: 11028285
    Abstract: Provided is a compound capable of forming a coating layer that has excellent scratch resistance and still has stain resistance (in particular, stain resistance against hair dyes) and workability (impact resistance) both at satisfactory levels. The urethane (meth)acrylate has a cyclic structure in a molecule. The urethane (meth)acrylate has a total weight of carbon, oxygen, nitrogen, and sulfur atoms constituting the ring or rings of the cyclic structure of 10 percent by weight or more based on the total amount (100 percent by weight) of the urethane (meth)acrylate. The urethane (meth)acrylate also has an average number of functional groups of 3.5 to 4.5.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: June 8, 2021
    Assignee: DAICELL-ALLNEX LTD.
    Inventor: Fumio Tanabiki
  • Patent number: 11011943
    Abstract: Embodiments disclosed herein describe a wireless power receiving system for an electronic device includes: a first inductor coil configured to receive power primarily at a first frequency and from magnetic fields propagating in a first direction; and a second inductor coil configured to receive power primarily at a second frequency and from magnetic fields propagating in a second direction, wherein the first frequency is different than the second frequency.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: May 18, 2021
    Assignee: Apple Inc.
    Inventors: Michael B. Wittenberg, Makiko K. Brzezinski, Stefan A. Kowalski, Christopher S. Graham, Morgan T. McClure, Erik G. de Jong, Trevor J. Ness, Peter J. Kardassakis, Jayesh Nath, Adam T. Clavelle, Rex Tyler Ehman
  • Patent number: 10966929
    Abstract: The present invention provides: a freeze-dried composition which comprises (a) a monovalent metal alginate and (b) a salt selected from a monovalent metal salt and an ammonium salt; and a method of producing a freeze-dried monovalent metal alginate composition which comprises the steps of freezing an aqueous solution formed by dissolving at least the component (a) and the component (b), performing first drying, and then performing second drying as desired to reduce a water content to 3% by mass or less. This is a freeze-dried monovalent metal alginate composition with suppressed viscosity decrease with the lapse of time.
    Type: Grant
    Filed: September 6, 2016
    Date of Patent: April 6, 2021
    Assignee: MOCHIDA PHARMACEUTICAL CO., LTD.
    Inventors: Shuichi Endo, Naoya Yoshioka
  • Patent number: 10946487
    Abstract: A method for producing a turbomachine impeller, which has a radially inner hub body, a radially outer shroud body and blades extending between the hub body and the shroud body. The blades, the hub body and the shroud body are designed as an integral, monolithic assembly includes providing a blank; milling the blank to form a basic contour of the hub body, the shroud body, and the blades; performing build-up welding or additive manufacturing at least once on the main contour that is formed and subsequently performing milling at least once on portions that are formed by the build-up welding.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: March 16, 2021
    Assignee: MAN Energy Solutions SE
    Inventors: Matthias Dommermuth, Sascha Schob
  • Patent number: 10874763
    Abstract: This invention provides porated cartilage products, methods of producing porated cartilage products, and methods of treating subjects by administering cartilage products. Optionally, the cartilage products are sized, porated, and digested to provide a flexible cartilage product. Optionally, the cartilage products comprise viable chondrocytes, bioactive factors such as chondrogenic factors, and a collagen type II matrix. Optionally, the cartilage products are non-immunogenic.
    Type: Grant
    Filed: August 20, 2014
    Date of Patent: December 29, 2020
    Assignee: Osiris Therapeutics, Inc.
    Inventors: Dana Yoo, Jin-Qiang Kuang, Jaime Paden, Scott Maxson, Alla Danilkovitch, Erasmo Lopez, Samson Tom
  • Patent number: 10835663
    Abstract: A subcutaneous implantable device for guiding a vascular access member, the device including a channel defined by a through-hole in the device, wherein the channel is configured to guide the vascular access member there-through to a vascular site; and anchoring means adapted for fixedly attaching, in a form of using suture, tissue ingrowth, tissue encapsulation or tissue adhesion, the device to at least one of a dermis or a subcutaneous tissue at a position underneath the dermis to allow repeated access of the vascular access member through the channel to the vascular site, wherein the device is dimensioned to allow the device to be attached through the anchoring means for anchoring the entire device at a distance away from the vascular site, A method of creating scar tissue track for vascular access is also disclosed where the subcutaneous implantable device for guiding vascular access member is first implanted sub-dermally, the dermis is palpated to feel for the device location and orientation, the guiding
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: November 17, 2020
    Assignees: Agency for Science, Technology and Research, Singapore Health Services Pte Ltd
    Inventors: Ruey Feng Peh, Soo Ghim Lim, Yee Han Kuan, Yanling Toh, Hsien Ts'ung Tay, Seck Guan Tan
  • Patent number: 10814124
    Abstract: An electrical connector, in particular for a medical device that is intended to be secured to the skin of a user, the connector comprising a base intended to be solidly connected to the device and a plug intended to be solidly connected to an electric conductor, wherein the plug comprises a connection means and the base comprises a plurality of connection means, each being adapted to engage with the connection means of the plug in order to establish a connection between the base and the plug comprising a base secured to the device and a plug configured to be secured to an electrical conductor, wherein the base includes a plurality of protuberances and the plug includes a cavity.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: October 27, 2020
    Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Simon Perraud, Fabrice Emieux, Nicolas Karst, Philippe Pantigny
  • Patent number: 10756043
    Abstract: Plural medical device formed from one or more layers of thin film polymer are assembled from a single polymer coupon. Initially the coupon is bonded to a rigid substrate. Force, heat and a suction are selectively applied to the coupon to ensure that it has a consistent height across its exposed surface. Once the polymer coupon is bonded the components forming the medical device are attached to the coupon and the coupon is shaped to form the individual medical devices. Shaped sections of the coupon are then lifted off the rigid backing. The lifted off sections on which the components were attached are the medical devices.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: August 25, 2020
    Assignee: Stryker Corporation
    Inventors: John Janik, Robert Brindley, Edward Chia-Ning Tang
  • Patent number: 10575959
    Abstract: An orthopedic device for implanting between adjacent vertebrae comprising: an arcuate balloon and a hardenable material within said balloon. In some embodiments, the balloon has a footprint that substantially corresponds to a perimeter of a vertebral endplate. An inflatable device is inserted through a cannula into an intervertebral space and oriented so that, upon expansion, a natural angle between vertebrae will be at least partially restored. At least one component selected from the group consisting of a load-bearing component and an osteobiologic component is directed into the inflatable device through a fluid communication means.
    Type: Grant
    Filed: July 3, 2016
    Date of Patent: March 3, 2020
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Thomas M. DiMauro, Michael Andrew Slivka
  • Patent number: 10524973
    Abstract: A movement assistance device is provided with thigh frames, lower leg frames, and knee joint mechanisms which are disposed on the outer side and the inner side, respectively, of each knee of a person to be assisted. Each of the thigh frames has a first main frame, which extends in the longitudinal direction of a thigh from a base disposed on one side of the hip of the person to be assisted to the outer knee joint mechanism, a second main frame, which obliquely extends on the front side of the thigh from the base to the inner knee joint mechanism, and a body support member, which is extended between the two main frames on the rear surface side of the thigh.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: January 7, 2020
    Assignee: Honda Motor Co., Ltd.
    Inventors: Yoshinao Sodeyama, Toru Takenaka, Hiroshi Gomi, Yosuke Ikedo, Kenichi Katagiri
  • Patent number: 10492899
    Abstract: A full-function artificial organ fitting body comprises a cortex layer and an organ body tissue area. The organ body tissue area comprises a growth area, a differentiation area, a docking area, a branch arterial system, a branch nervous system and a branch venous system. The branch arterial system, the branch nervous system and the branch venous system are distributed in the differentiation area and form a main body three-dimensional skeleton structure with the outer growth area and the middle docking area.
    Type: Grant
    Filed: September 4, 2017
    Date of Patent: December 3, 2019
    Inventor: Chang Liu
  • Patent number: 10485665
    Abstract: Apparatus and method for constructing a cartilage structure preferably has a first plate, and a blade mounted over the first plate. The blade preferably has (i) a predetermined shape, and (ii) a cutting edge protruding from the first plate and configured to cut a cartilage into the predetermined shape. A second plate preferably has a guide imprint adjacent a surface thereof, the guide imprint having a shape complimentary to the predetermined shape of the blade. A press preferably has (i) a first surface configured to mount the first plate, and (ii) a second surface configured to mount the second plate. Actuation structure is preferably configured to press together the press first and second surfaces to thereby cause the blade to cut the cartilage in the predetermined shape. The method utilizes similar structure to prepare at least two cartilages, which are joined together to form a three-dimensional cartilage structure.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: November 26, 2019
    Assignee: ReconstratA, LLC
    Inventors: Anirudh Arun, Angelo Alberto Leto Barone
  • Patent number: 10342663
    Abstract: Embodiments of the invention include a disc or vertebral defect packing tape for use in disc fusion, disc regeneration or for the creation of artificial disks. The tape comprises a tape body and one or more support members. Each of the support members is contained within the tape body and/or adhered to an external surface of the tape or tape body. The tape body is configured as a packing material and each of the support members is configured to hold the tape body together.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: July 9, 2019
    Assignee: Perumala Corporation
    Inventor: Madhavan Pisharodi
  • Patent number: 10179180
    Abstract: The invention relates in various embodiments to a composite useful as e.g. a medical implant device, and a method of treating fouling, including biofouling as may occur on an implant. The composite comprises a matrix phase and a patterned phase that comprises an energetically activatable wire intermixed with the matrix phase, the wire when energetically activated, which includes thermal activation, causes modification of at least a portion of the matrix phase to treat fouling that might otherwise occur. The method of treating biofouling may be practiced on a patent while the medical implant of the invention is in situ.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: January 15, 2019
    Assignee: UT-BATTELLE, LLC
    Inventors: Steve L. Allman, Mitchel J Doktycz, Scott T Retterer, David P. Allison
  • Patent number: 10179129
    Abstract: A method of treating or preventing capsular contracture in a patient resulting from surgical insertion of a silicone breast implant in a surgically created implant pocket. The method includes administering to the patient a therapeutically effective amount of a leukotriene receptor antagonist prior to the formation of a capsular contracture in the patient. The method further includes administering a therapeutically effective amount of displacement of the breast implant within the surgically created implant pocket, the therapeutically effective amount of displacement of the breast implant being administered post-surgically but prior to the formation of a capsular contracture in the patient.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: January 15, 2019
    Inventor: Stephen David Bresnick
  • Patent number: 10137014
    Abstract: A stent (32) configured to be placed in a body lumen and having a tubular shape formed by a structure that is expandable and contractible skeleton (18, 19) in a radial direction, the skeleton (18, 19) having a heteromorphic structure due to changes of a cross section shape thereof in a thickness direction. A stent (10) that is expandable and contractible in the radial direction while being configured to be placed in a body lumen, the stent (10) having a heteromorphic tubular shape, a cross section shape of which changes in a lengthwise direction, and having a metal skeleton (18, 19) formed by at least one of electroforming and etching.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: November 27, 2018
    Assignee: NIPRO Corporation
    Inventors: Yoshihiko Sano, Yasushi Ooyama, Katsuhiro Hiejima, Kouji Akimoto
  • Patent number: 10130737
    Abstract: The present invention provides tissues derived from animals, which lack any expression of functional alpha 1,3 galactosyltransferase (alpha-1,3-GT). Such tissues can be used in the field of xenotransplantation, such as orthopedic reconstruction and repair, skin repair and internal tissue repair or as medical devices.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: November 20, 2018
    Assignee: Revivicor, Inc.
    Inventors: David Ayares, Paul Rohricht
  • Patent number: 10098681
    Abstract: A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust the release of the substance. In various embodiments, the covering may be formed of a collagen material and is suitable for a variety of procedure specific uses.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: October 16, 2018
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Guobao Wei, Todd M. Boyce, Robert Cohen, Cristy Richards, Lawrence A. Shimp
  • Patent number: 10092409
    Abstract: A device and method of manufacturing and implanting a custom subtalar arthroereisis implant having side surfaces which are mirrored in topography with the sinus tarsi of a patient. The implant is formed using images of the patient standing in a weight bearing position with their sinus tarsi and the surrounding bone structure in an anatomically correct alignment. Once implanted, the implant urges and maintains the anatomically correct alignment thereby minimizing any patient tendency for abnormal motion between said patent's talus and calcaneus.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: October 9, 2018
    Inventor: Kent A. Feldman
  • Patent number: 10052186
    Abstract: A prosthetic implant includes an anterior surface, configured for at least partial contact with an underside of a patient's facial soft tissue. A posterior surface is oppositely placed to the anterior surface. The posterior surface is configured for at least partial contact with a patient's facial bony tissue when the anterior surface is in at least partial contact with the patient's facial soft tissue. An implant body is defined by the anterior and posterior surfaces and extends transversely therebetween. A selected portion of the posterior surface has a texture that mechanically differs from a texture of a majority of the anterior surface.
    Type: Grant
    Filed: October 9, 2014
    Date of Patent: August 21, 2018
    Assignees: OSTEOSYMBIONICS LLC, THE CLEVELAND CLINIC FOUNDATION
    Inventors: Francis A. Papay, Jessie San, Nicholas T. Wilkins, Cameron J. Fordyce
  • Patent number: 10034373
    Abstract: An electronic device having a circuit board and a battery is disclosed. The circuit board may include a through hole and an electrical pad surrounding the through hole. In order to electrically couple the circuit board to the battery, and in particular, an electrode of the battery, a tab (or plaque) is placed between the electrical pad and the electrode. The tab electrically couples with the electrical pad by a soldering operation. To couple (electrically and mechanically) the tab with the electrode, a welding operation is used. The welding operation may include a laser weld providing thermal energy through a laser beam. In this regard, the laser beam passes through the through hole, thereby (partially) melting the tab and forming a weld between the tab and the electrode. Accordingly, the tab covers the through hole such that the tab is positioned to receive the laser beam.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: July 24, 2018
    Assignee: Apple Inc.
    Inventors: Charles W. Werley, Haran Balaram, Richard L. Winslow
  • Patent number: 9949742
    Abstract: The invention concerns an accessory for removing material, in particular a file (3) or a cutting block, for prosthesis implantation surgery, in particular for hip or knee prostheses. The invention is characterised in that it comprises at least partly one plastic part and at least one insert (4, 10, 5) made of a material harder than the bone material, in particular of metal, which is fixed to the plastic material such that if the device is brought to a temperature Ti, the insert is separated from the plastic material.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: April 24, 2018
    Inventor: Jean-Francois Biegun
  • Patent number: 9867686
    Abstract: The implantable hernia prosthesis of the present invention comprises at least one piece of mesh (1) arranged to cover at least a portion of the hernia, at least one support element (2) attached to said piece of mesh (1), said support element (2) comprising at least one resilient, deformable biasing filament, characterized by said support element (2) being an uninterrupted tension providing ring surrounding a portion of said mesh (1) and further comprising an indentation directed towards the center of said ring.
    Type: Grant
    Filed: September 25, 2012
    Date of Patent: January 16, 2018
    Assignee: Bard Shannon Limited
    Inventors: Rui Manuel De Melo Soares Da Costa, Augusto Manuel De Almeida Lourenço
  • Patent number: 9848994
    Abstract: The present application generally relates to orthopedic systems, and in particular, to systems including independent plates and spacers. A plating system can include a spacer and a plate that is independent from the spacer. A number of locking mechanisms can be provided to secure the plate to the spacer. In some cases, the spacer includes a pair of notches that extend on an outer surface of the spacer. The plate can include a pair of lateral extensions that can engage the notches to secure the plate to the spacer. In other cases, the spacer includes an opening including a pair of inlets. The plate can include an enclosed posterior extension that can be received in the pair of inlets to secure the plate to the spacer.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: December 26, 2017
    Assignee: GLOBUS MEDICAL, INC.
    Inventors: Samuel Petersheim, Jason Cianfrani, Aditya Ingalhalikar, Jennifer Klimek, Jason Gray
  • Patent number: 9808616
    Abstract: The present disclosure provides a regenerative peripheral nerve interface (RPNI) for a subject comprising an insulating substrate, at least one metallic electrode deposited onto the insulating substrate forming a thin-film array; a portion of the at least one metallic electrode surface having a layer of a first conductive polymer and a layer of decellularized small intestinal submucosa (SIS) coating a portion of the electrode, wherein a second conductive polymer is electrochemically polymerized through the SIS to form the regenerative peripheral nerve interface. The present disclosure also provides that a layer of muscle tissue contacts the regenerative peripheral nerve interface.
    Type: Grant
    Filed: January 13, 2012
    Date of Patent: November 7, 2017
    Assignees: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, UNIVERSITY OF DELAWARE
    Inventors: Paul S. Cederna, Melanie G. Urbanchek, David C. Martin
  • Patent number: 9789458
    Abstract: The invention provides a method for increasing the order of an array of polymeric micelles or of nanoparticles on a substrate surface comprising a) providing an ordered array of micelles or nanoparticles coated with a polymer shell on a substrate surface and b) annealing the array of micelles or nanoparticles by ultrasonication in a liquid medium which is selected from the group comprising H2O, a polar organic solvent and a mixture of H2O and a polar organic solvent. In a related aspect, the invention provides the highly ordered arrays of micelles or nanoparticles obtainable by the methods of the invention.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: October 17, 2017
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Christian Williges, Christoph Morhard, Joachim P. Spatz, Robert Brunner
  • Patent number: 9782515
    Abstract: A method for treating an oral condition of a subject by grafting cultured tissue constructs to the oral tissue. The cultured tissue constructs comprise cultured cells and endogenously produced extracellular matrix components without the requirement of exogenous matrix components or network support or scaffold members. Some tissue constructs of the invention are comprised of multiple cell layers or more than one cell type. The tissue constructs of the invention have morphological features and functions similar to tissues their cells are derived and their strength makes them easily handleable. Preferred cultured tissue constructs of the invention comprise cells derived from human tissue.
    Type: Grant
    Filed: March 5, 2007
    Date of Patent: October 10, 2017
    Assignee: Organogenesis, Inc.
    Inventor: Dario C. Eklund
  • Patent number: 9713524
    Abstract: Human implantable tissue expanders are provided, that comprise an inner foam filling enclosed within a substantially non-stretchable resilient expansion restricting layer configured to retain a shape and/or volume of said foam filling upon changes of ambient pressure and/or temperature, and an outer shell comprising one or more layers formed of a resilient material.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: July 25, 2017
    Assignee: IMPLITE LTD.
    Inventor: Ami Glicksman
  • Patent number: 9687332
    Abstract: A method and device for treating hernia by implanting at least one collapsible hernia repair patch, such as a planar mesh body at least partially enveloped by one or more elastic collars. A posterior end of an applicator carrying the repair patch may be inserted through a hernia and into the wall of the abdominal cavity, and the patch may be released into the cavity, e.g., so as to helically deploy the patch such that the patch lies in parallel to the abdominal wall. A balloon, which is removably attached to the patch, may be inflated to help move the patch to a deployed configuration, and thereafter the balloon removed from the hernia site.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: June 27, 2017
    Assignee: Davol, Inc.
    Inventors: Mordehai Sholev, Ibrahim Matter, Ziv Tamir
  • Patent number: 9687347
    Abstract: A percutaneous implant (10) comprises a bone-fixation portion (20), a spigot portion (50) for the attachment of an external prosthesis, and a pear-shaped portion (40) having a porous outer region (44) comprising a mesh of wire mesh material around a central core. The portion (40) is disposed between the spigot portion (50) and a collar (30) which has a plurality of through holes (34) adjacent to its edge. The bone-fixation portion (20) may have extending parallel thereto a plate (72) for attachment to the side of a bone.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: June 27, 2017
    Assignee: FITZBIONICS LIMITED
    Inventor: Martin Noel Fitzpatrick
  • Patent number: 9659152
    Abstract: A technique for generating a data set that geometrically defines a bone cut configuration for transverse maxillary distraction is using a computer-implemented method. An aspect of the technique comprises creating a numeric model of a maxilla based on patient-specific data of the maxilla. The numeric model is representative of mechanical properties of the maxilla. Based on the numeric model thus generated, one or more cut configurations for one or more bone cuts on at least one of a left hand side and a right hand side of the maxilla are determined. Each cut configuration has been determined to compensate for asymmetric mechanical properties of the maxilla. In a further step, a data set indicative of the one or more cut configurations thus determined is generated. The data set may be used to create a surgical template or jig, for computer-assisted surgery or a surgical navigation system.
    Type: Grant
    Filed: April 10, 2014
    Date of Patent: May 23, 2017
    Inventor: Christoph Mueller
  • Patent number: 9636438
    Abstract: The present invention relates to a temporary composite scaffold comprising discrete ECM particles formed as a fistula plug. We demonstrate that when using scaffolds containing ECM material, higher concentrations of ECM surprisingly do not give better cell morphology. Concentrations lower than 60% (w/w) are sufficient to obtain the best cell morphology and distribution.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: May 2, 2017
    Assignee: Coloplast A/S
    Inventors: Lene Feldskov Nielsen, Jens Hoeg Truelsen, Hanne Everland
  • Patent number: 9629946
    Abstract: A polymeric product including at least two layers, wherein a functional layer includes a polymeric material and at least one anti-microbial substance, and a protective layer, including a polymeric material arranged outside the functional layer and completely covering the functional layer, wherein the protective layer does not include any anti-microbial substances. A method of producing the product, the use of the same and a kit for producing the product.
    Type: Grant
    Filed: September 13, 2011
    Date of Patent: April 25, 2017
    Assignee: NANEXA AB
    Inventors: Anders Johansson, Marten Rooth
  • Patent number: 9605349
    Abstract: Methods of manufacturing produce metal implants having nano-modified surfaces that contain antimicrobial properties. The methods may include immersing the implant in an acid, rinsing the acid-treated implant in an aqueous cleaner, and thereafter heating the rinsed implant. The nano-modified implants described herein may contain an increased surface roughness; surface features with increased width or height; and/or decreased surface energy. The implants that result from these methods contain a nano-modified surface that is resistant to microbial cell adhesion and ultimately reduce biomaterials-related infections at the implant site.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: March 28, 2017
    Assignee: Howmedica Osteonics Corp.
    Inventors: Thomas J. Webster, Godofredo R. Dimaano, Kevor Shane Tenhuisen, Gene Kulesha, John Muth