Lens Has Specific Glass Transition Temperature Patents (Class 623/6.58)
  • Patent number: 9414908
    Abstract: According to a first aspect, the invention relates to an intraocular variable focus implant comprising a non-conducting liquid with a melting temperature above 0° C., a conducting liquid, a liquid interface formed by the non-conducting and conducting liquids, a first electrode in contact with the conducting liquid, a second electrode insulated from the conducting liquid, wherein the liquid interface is movable by electro wetting according to a change in a voltage applied between the first and second electrodes.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: August 16, 2016
    Assignee: PARROT DRONES
    Inventor: Mathieu Maillard
  • Patent number: 9289531
    Abstract: High refractive index acrylic device materials with reduced glistenings are disclosed. The device materials are particularly suitable for use as ophthalmic or otorhhinolaryngological device materials and comprises a poly(phenyl ether)-containing monomer and/or a poly(phenyl ether)-containing cross-linking agent.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: March 22, 2016
    Assignee: Novartis AG
    Inventors: Xuwei Jiang, Douglas Schlueter, Walter Laredo
  • Publication number: 20140277438
    Abstract: Ophthalmic devices suitable for implantation into the eye through small incisions or insertion into an existing orifice are disclosed. These devices are made from a composition comprising crystalline or semi-crystalline polymeric materials which have a glass transition temperature (Tg) of from about ?100° C. to about 37° C., and wherein Tg for the material is lower than Tm for the composition. Disclosed devices include intraocular lenses, corneal inlays, drug delivery devices and implants for reducing intraocular pressure in glaucoma patients.
    Type: Application
    Filed: March 11, 2014
    Publication date: September 18, 2014
    Applicant: Medennium, Inc.
    Inventors: Christopher WILCOX, Christine Liau, Stephen Zhou, Igor Valyunin
  • Patent number: 8685089
    Abstract: A shape memory polymer (SMP) intraocular lens may have a refractive index above 1.45, a Tg between 10° C. and 60° C., inclusive, de minimis or an absence of glistening, and substantially 100% transmissivity of light in the visible spectrum. The intraocular lens is then rolled at a temperature above Tg of the SMP material. The intraocular device is radially compressed within a die to a diameter of less than or equal to 1.8 mm while maintaining the temperature above Tg. The compressed intraocular lens device may be inserted through an incision less than 2 mm wide in a cornea or sclera or other anatomical structure. The lens can be inserted into the capsular bag, the ciliary sulcus, or other cavity through the incision. The SMP can substantially achieve refractive index values of greater than or equal to 1.45.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: April 1, 2014
    Assignee: The Regents of the University of Colorado
    Inventors: Malik Y. Kahook, Naresh Mandava, Robin Shandas, Bryan Rech
  • Patent number: 8247511
    Abstract: The current invention provides a method of forming a foldable intraocular having a high refractive index from a copolymer comprising a first monomer comprising an aryl acrylate or an aryl methacrylate; a second monomer comprising an aromatic ring comprising a substituent having one ethylenic unsaturation, provided that the second monomer is not an aryl acryate or aryl methacrylate, and a third monomer comprising one ethylenic unsaturation that, if polymerized into a homopolymer, forms a high water content hydrogel; and, optionally, a cross-linking agent.
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: August 21, 2012
    Assignee: Advanced Vision Science, Inc.
    Inventor: Khalid Mentak
  • Patent number: 7923520
    Abstract: The present invention relates to high refractive index monomers according to formula (I) and (co)polymers comprising such high refractive index monomers. The 5 (co)polymers are highly suitable for the manufacture of optical articles, in particular flexible optical articles, more in particular intraocular lenses.
    Type: Grant
    Filed: February 14, 2007
    Date of Patent: April 12, 2011
    Assignee: Procornea Holding B.V.
    Inventors: Bernardus Franciscus Maria Wanders, Henk Haitjema
  • Patent number: 7763682
    Abstract: Intraocular lenses comprised of an acrylic-silicone hybrid polymer are disclosed. The intraocular lenses described herein are suitable for insertion through incisions of 2 mm or less.
    Type: Grant
    Filed: March 27, 2006
    Date of Patent: July 27, 2010
    Assignee: Abbott Medical Optics Inc.
    Inventors: Michael D. Lowery, Harish C. Makker
  • Patent number: 7652076
    Abstract: Disclosed are soft, high refractive index device materials having improved strength. The materials contain a monofunctional or difunctional, acrylate or methacrylate terminated aromatic functional methacrylic or acrylic macromer.
    Type: Grant
    Filed: June 12, 2006
    Date of Patent: January 26, 2010
    Assignee: Alcon, Inc.
    Inventors: Douglas C. Schlueter, Mutlu Karakelle
  • Patent number: 7232896
    Abstract: A colorant for ocular lenses represented by the formula (I) defined herein or a colorant for ocular lenses represented by the formula (II) defined herein.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: June 19, 2007
    Assignee: Nidek Co., Ltd.
    Inventors: Sadao Miki, Masaki Kuwahara, Yoshihiro Nakahata, Tsutomu Sunada
  • Patent number: 7083645
    Abstract: A high refractive index, foldable polymer suitable for use in ophthalmic devices, such as intraocular lenses, is provided. The polymer may be produced from a polymerization reaction of first, second and third monomeric components and a crosslinking agent. The first monomeric component includes an aryl acrylate or an aryl methacrylate. The second monomeric component, which is not an acrylate, includes a monomer having an aromatic ring with a substituent having at least one site of ethylenic unsaturation. The third monomeric component includes a high water content hydrogel-forming monomer. The resulting high refractive index copolymer is durable enough to be cut and polished when dry, and becomes soft and foldable when hydrated.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: August 1, 2006
    Assignee: Advanced Vision Science, Inc.
    Inventor: Khalid Mentak
  • Patent number: 6679605
    Abstract: Ophthalmic devices suitable for implantation into the eye through small incisions are disclosed. These devices are made from a composition comprising crystalline or semi-crystalline polymeric materials which have a glass transition temperature (Tg) of from about −100° C. to about 20° C., a melting point temperature (Tm) of from about 0° C. to about 37° C., and wherein Tg for the material is lower than Tm for the composition. Disclosed devices include intraocular lenses, corneal inlays, ocular drug delivery devices and implants for reducing intraocular pressure in glaucoma patients; intraocular lenses are preferred.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: January 20, 2004
    Assignee: Medennium, Inc.
    Inventors: Stephen Q. Zhou, Christopher D. Wilcox, Christine Liau, Igor Valyunin
  • Patent number: 6635731
    Abstract: A high refractive index, foldable polymer suitable for use in ophthalmic devices, such as intraocular lenses, is provided. The polymer may be produced from a polymerization reaction of first, second and third monomeric components and a crosslinking agent. The first monomeric component includes an aryl acrylate or an aryl methacrylate. The second monomeric component, which is not an acrylate, includes a monomer having an aromatic ring with a substituent having at least one site of ethylenic unsaturation. The third monomeric component includes a high water content hydrogel-forming monomer. The resulting high refractive index copolymer is durable enough to be cut and polished when dry, and becomes soft and foldable when hydrated.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: October 21, 2003
    Assignee: Surgidev Corporation
    Inventor: Khalid Mentak
  • Patent number: 6635732
    Abstract: A high refractive index, foldable polymer suitable for use in ophthalmic devices, such as intraocular lenses, is provided. The polymer may be produced from a polymerization reaction of first, second and third monomeric components and a crosslinking agent. The first monomeric component includes an aryl acrylate or an aryl methacrylate. The second monomeric component, which is not an acrylate, includes a monomer having an aromatic ring with a substituent having at least one site of ethylenic unsaturation. The third monomeric component includes a high water content hydrogel-forming monomer. The resulting high refractive index copolymer is durable enough to be cut and polished when dry, and becomes soft and foldable when hydrated.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: October 21, 2003
    Assignee: Surgidev Corporation
    Inventor: Khalid Mentak
  • Patent number: 6541572
    Abstract: Disclosed is a two-step method of making soft, high refractive index, acrylic ophthalmic device materials. In the first step, a copolymer containing pendant oxirane groups is formed by copolymerizing one or more aryl acrylic hydrophobic monomers with one or more compounds of the formula wherein X is H or CH3; and n is 1-4. In the second step, the copolymer containing pendant oxirane groups formed in the first step is reacted with a compound of the formula W—T—H wherein W is H, CH3(CH2)a, or Z(OCH2CH2)b; a is 0-3; b is 1-5; Z is H, or CH3(CH2)p; p is 0-3; and T is O, NH, S; provided that if T≠O, then W≠H.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: April 1, 2003
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Albert R. LeBoeuf
  • Publication number: 20020161437
    Abstract: Ophthalmic devices suitable for implantation into the eye through small incisions are disclosed. These devices are made from a composition comprising crystalline or semi-crystalline polymeric materials which have a glass transition temperature (Tg) of from about −100° C. to about 20° C., a melting point temperature (Tm) of from about 0° C. to about 37° C., and wherein Tg for the material is lower than Tm for the composition. Disclosed devices include intraocular lenses, corneal inlays, ocular drug delivery devices and implants for reducing intraocular pressure in glaucoma patients; intraocular lenses are preferred.
    Type: Application
    Filed: February 28, 2001
    Publication date: October 31, 2002
    Applicant: Medennium, Inc.
    Inventors: Stephen Q. Zhou, Christopher D. Wilcox, Christine Liau, Igor Valyunin
  • Publication number: 20020019492
    Abstract: Disclosed is a two-step method of making soft, high refractive index, acrylic ophthalmic device materials.
    Type: Application
    Filed: September 17, 2001
    Publication date: February 14, 2002
    Inventor: Albert R. LeBoeuf
  • Publication number: 20020016629
    Abstract: The present invention relates to methods of implementing an optical element having a refraction modulating composition. The methods include using a wavefront sensor to provide an optical measurement of the optical element. The present invention also relates to systems comprising an optical element having a refraction modulating composition and a wavefront sensor.
    Type: Application
    Filed: March 20, 2001
    Publication date: February 7, 2002
    Inventors: Christian A. Sandstedt, Jagdish M. Jethmalani, Robert H. Grubbs, Julia A. Kornfield, Daniel M. Schwartz, Robert Maloney
  • Publication number: 20010037150
    Abstract: IOL bodies comprising materials having a Fibronectin/Vitronectin Compatibility Index>1 and a Lens Epithelial Cell Growth Biocompatibility Index≧1 on their posterior surface have a low incidence of posterior capsule opacification.
    Type: Application
    Filed: April 5, 2001
    Publication date: November 1, 2001
    Inventors: Kwan Y. Chan, Mutlu Karakelle, Reijo Linnola
  • Publication number: 20010000351
    Abstract: A method of selecting an intraocular lens material for reducing the risk of posterior capsule opacification is disclosed. The method comprises determining the tack of the material.
    Type: Application
    Filed: December 1, 2000
    Publication date: April 19, 2001
    Inventor: Charles Freeman