Eye Patents (Class 623/905)
  • Patent number: 8961600
    Abstract: A fiber matrix is provided for maintaining space in soft tissue, for example for use in procedures for assisting drainage of aqueous humor from an eye to treat glaucoma. The fiber matrix comprises a plurality of crossing fibers forming a mesh with a plurality of void spaces. The fibers and void spaces are sized and arranged so as to permit passage of fluid through the fiber matrix and to inhibit formation of scar tissue through the fiber matrix. The fibers may comprise a polymeric material, and the fiber matrix may be manufactured by electrospinning. The fibers may comprise a biostable and/or a biodegradable material. In one method of using a fiber matrix, the fiber matrix is positioned under a scleral flap, with at least part of the fiber matrix under the scleral flap.
    Type: Grant
    Filed: June 25, 2010
    Date of Patent: February 24, 2015
    Assignee: Optonol Ltd.
    Inventors: Oded Nissan, Ira Yaron, Jonathan Ben-Zvi
  • Patent number: 8920357
    Abstract: Treating glaucoma utiilizing a shunt having an elastormeric plate and a non-valved elastomeric drainage tube. The plate is positioned over a sclera with an outflow end of the elastomeric drainage tube open to an outer surface of the plate. An inflow end of the drainage tube tunnels through the sclera and cornea to the anterior chamber of the eye. The drainage tube collapses upon initial insertion within an incision in the sclera and cornea, or at a kink on the outside of the incision, but has sufficient resiliency to restore its patency over time. The effect is a flow restrictor that regulates outflow from the eye until a bleb forms around the plate. The plate desirably has a peripheral ridge and a large number of fenestrations, and a longer suturing tab extending from one side of the plate to enhance visibility and accessibility when suturing the shunt to the sclera.
    Type: Grant
    Filed: December 13, 2012
    Date of Patent: December 30, 2014
    Assignee: Abbott Medical Optics Inc.
    Inventor: George Baerveldt
  • Patent number: 8900299
    Abstract: A method for prevention of migration of epithelial cells in a capsular bag of an eye of a mammal is provided. The method comprises removing the natural lens of the eye from the capsular bag; introducing an object with at least one sharp edge into the capsular bag, in such a way that said sharp edge contacts the inside of the capsular bag to form a barrier preventing migration of epithelial cells across said barrier; and injecting a lens-forming composition into the capsular bag.
    Type: Grant
    Filed: August 31, 2009
    Date of Patent: December 2, 2014
    Assignee: AMO Groningen B.V.
    Inventor: Thomas Terwee
  • Patent number: 8834406
    Abstract: A biocompatible glaucoma drainage device, comprising a non-porous element, a porous element, an anchoring assembly disposed around the non-porous element, wherein the anchoring assembly comprises a plurality of barbs extending outwardly therefrom.
    Type: Grant
    Filed: October 22, 2012
    Date of Patent: September 16, 2014
    Assignee: Snyder Biomedical Corporation
    Inventors: Robert W. Snyder, John A. Martens, Robert Munger
  • Patent number: 8808219
    Abstract: Implants and methods for treating ocular disorders are described. One method involves providing an elongated delivery device and an implant mounted at a distal end of the delivery device. An incision is formed in eye tissue and the implant is inserted the through the incision using the delivery device. The implant is implanted at a location communicating with a physiologic outflow pathway of an eye such that a distal end portion of the implant and a proximal end portion of the delivery device are relatively disposed in a non-linear orientation during implantation. In one method, the implant is non-linear after insertion.
    Type: Grant
    Filed: February 5, 2009
    Date of Patent: August 19, 2014
    Assignee: Glaukos Corporation
    Inventors: Olav B Bergheim, Morteza Gharib
  • Patent number: 8128228
    Abstract: Axial distances between ocular structures can be measured by focusing an optical unit on focus planes corresponding to the ocular structures and using the distance between focus planes to determine the distance between the ocular structures. The method is particularly useful during eye surgery, e.g., cataract surgery, where the distance between ocular structures, particularly an aphakic pupil, can be used to more accurately predict the effective lens position for an intraocular lens.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: March 6, 2012
    Assignee: WF Systems LLC
    Inventor: Anthony Y. Van Heugten
  • Patent number: 8122596
    Abstract: An image is captured or otherwise converted into a signal in an artificial vision system. The signal is transmitted to the retina utilizing an implant. The implant consists of a polymer substrate made of a compliant material such as poly(dimethylsiloxane) or PDMS. The polymer substrate is conformable to the shape of the retina. Electrodes and conductive leads are embedded in the polymer substrate. The conductive leads and the electrodes transmit the signal representing the image to the cells in the retina. The signal representing the image stimulates cells in the retina.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: February 28, 2012
    Assignees: Lawrence Livermore National Security, LLC, Doheny Eye Institute
    Inventors: Peter Krulevitch, Dennis L. Polla, Mariam N. Maghribi, Julie Hamilton, Mark S. Humayun, James D. Weiland
  • Patent number: 8002828
    Abstract: Various polymers are provided that can be polymerized in the lens capsule with the ability to covalently bond an intraocular lens implant to the posterior capsule of the eye such that there is no space available between the intraocular lens implant and the lens capsule for lens epithelial cells to proliferate and thereby significantly reducing posterior capsule opacification.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: August 23, 2011
    Inventor: Leonard Pinchuk
  • Patent number: 7981154
    Abstract: The present invention is in the field of ophthalmic surgery and relates to a method for the prevention of capsular opacification, especially after extraction of the natural lens from the lens capsule of the eye. Particular methods disclosed include replacing the natural lens with a capsule filling implant comprising an injectable material and injecting an agent capable of inhibiting the proliferation of lens epithelial cells, migration of lens epithelial cells, and/or production of extra-cellular matrix by lens epithelial cells into a space between the inserted capsule filling implant and the lens capsule using an instrument having a hydrophobic outer surface such that the composition reaches a germinative zone of the capsular bag.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: July 19, 2011
    Assignee: AMO Groningen B.V.
    Inventor: Thomas Terwee
  • Patent number: 7785285
    Abstract: A punctal plug inserted into the punctum-canaliculus, includes a shaft, a tip portion attached to one end of said shaft and a brim attached to the other end of said shaft, and a thin member penetrated into either one or all 3 out of said tip portion, shaft and brim, or said tip portion and shaft, or said shaft and brim. The thin member is thread 0.05 mm or less in diameter. The brim is disk shaped and the diameter of the brim is far smaller than the diameter of the tip. A protuberance is attached to the tip portion.
    Type: Grant
    Filed: May 26, 2004
    Date of Patent: August 31, 2010
    Assignee: MLC Limited Company
    Inventor: Katsuaki Kurihashi
  • Patent number: 7278999
    Abstract: The present invention relates to an ophthalmic surgery device comprising a handle presenting, at one of its ends, a first active part and, at the other of its ends, a second active part, characterized in that removable protection means are associated with at least one of the active parts. Therefore, the functional zones of the device thus protected do not risk being altered before use.
    Type: Grant
    Filed: March 24, 2003
    Date of Patent: October 9, 2007
    Assignee: Promepla S.A.
    Inventors: Marc Danchin, Alain Brocq
  • Patent number: 7160324
    Abstract: A method for prevention of migration of epithelial cells in a capsular bag of an eye of a mammal is provided. The method comprises removing the natural lens of the eye from the capsular bag; introducing an object with at least one sharp edge into the capsular bag, in such a way that said sharp edge contacts the inside of the capsular bag to form a barrier preventing migration of epithelial cells across said barrier; and injecting a lens-forming composition into the capsular bag.
    Type: Grant
    Filed: May 15, 2003
    Date of Patent: January 9, 2007
    Assignee: AMO Groningen, B.V.
    Inventor: Thomas Terwee
  • Patent number: 7060095
    Abstract: The present invention is directed to a supplemental endo capsular lens (SECL) and the method of inserting and embedding the SECL within either a gel or polymer, inside the capsule of the crystalline lens, during phaco-ersatz or similar surgical procedures in order to supplement the refractive power of the eye with a view to (1) correcting ametropia while (2) maintaining a useable amplitude of accommodation.
    Type: Grant
    Filed: May 8, 2001
    Date of Patent: June 13, 2006
    Assignee: Unisearch Limited
    Inventors: Arthur Ho, Paul Erickson, Fabrice Manns, Jean-Marie Parel
  • Patent number: 7009024
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.
    Type: Grant
    Filed: September 18, 2003
    Date of Patent: March 7, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
  • Patent number: 6989430
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.
    Type: Grant
    Filed: October 23, 2003
    Date of Patent: January 24, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler
  • Patent number: 6881809
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based silyl monomers or the copolymerization of one or more aromatic-based silyl monomers with one or more aromatic or non-aromatic non-siloxy-based monomers, hydrophobic monomers or hydrophilic monomers.
    Type: Grant
    Filed: May 18, 2004
    Date of Patent: April 19, 2005
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye, David P. Vanderbilt
  • Patent number: 6844414
    Abstract: Relatively high refractive index polymeric compositions and ophthalmic devices such as for example intraocular lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the copolymerization of one or more aromatic-substituted polysiloxane prepolymers with one or more aromatic monomers, alkylated monomers or hydrophilic monomers.
    Type: Grant
    Filed: January 26, 2004
    Date of Patent: January 18, 2005
    Assignee: Bausch and Lamb, Inc.
    Inventors: Yu-Chin Lai, Edmond T. Quinn
  • Publication number: 20040216749
    Abstract: A method of minimizing blood reflux from an episcleral vein during an ab interno eye surgery includes advancing an applicator from an anterior chamber through trabecular meshwork toward Schlemm's canal, and administering a vasoconstrictive agent to about Schlemm's canal for minimizing the blood reflux. The vasoconstrictive agent may be an alpha-adrenergic agonist.
    Type: Application
    Filed: January 23, 2004
    Publication date: November 4, 2004
    Inventor: Hosheng Tu
  • Publication number: 20040143324
    Abstract: Eye implant, comprising a flat element made of biocompatible material, said element being made at least partly opaque or light reflecting, such that in use the eye implant shall be visible, once implanted in an eye.
    Type: Application
    Filed: October 31, 2003
    Publication date: July 22, 2004
    Applicant: Medical Technology Transfer Holding B.V.
    Inventor: Gerrit Reinold Melles
  • Publication number: 20040118414
    Abstract: Disclosed are surface modified viscoelastics and methods of performing viscosurgery using polymer-containing irrigating solution to reduce cohesiveness of the viscoelastic agent at the interface, thereby improving its performance by reducing the occurrence of unintentional aspiration, especially in ocular surgery.
    Type: Application
    Filed: March 11, 2003
    Publication date: June 24, 2004
    Inventor: Mandar V Shah
  • Patent number: 6699210
    Abstract: A glaucoma shunt including first and second porous regions laminated together, and a third region having edge areas fused to edge areas of the second region so as to form a hollow reservoir therebetween. Also included is a catheter having a first end sandwiched between the second and third regions and a second end to be implanted into an anterior region of an eye. A method of making and surgically implanting such a glaucoma shunt is also included.
    Type: Grant
    Filed: April 27, 1999
    Date of Patent: March 2, 2004
    Assignee: The Arizona Board of Regents
    Inventors: Stuart K. Williams, Robert Snyder
  • Publication number: 20040034415
    Abstract: The present invention refers to a method of restoring the vision of an eye having an impaired lens with an artificial lens implant. The method involves replacing the lens by a polymerizable material injected into the emptied lens capsule and thereby providing a new lens implant with a predetermined refractive value, while admitting the possibility of controlling and adjusting the refractive value of the eye during the surgical process.
    Type: Application
    Filed: May 12, 2003
    Publication date: February 19, 2004
    Inventors: Thomas Henricus Marie Terwee, Hendrick Albert Weeber, Patricia Ann Piers
  • Patent number: 6692526
    Abstract: Improved ophthalmological surgical methods, systems and devices, employing a colorant.
    Type: Grant
    Filed: March 15, 2000
    Date of Patent: February 17, 2004
    Inventors: Michael E. Snyder, Robert J. Cionni, Scott E. Burk
  • Publication number: 20030216808
    Abstract: A method for prevention of migration of epithelial cells in a capsular bag of an eye of a mammal is provided. The method comprises removing the natural lens of the eye from the capsular bag; introducing an object with at least one sharp edge into the capsular bag, in such a way that said sharp edge contacts the inside of the capsular bag to form a barrier preventing migration of epithelial cells across said barrier; and injecting a lens-forming composition into the capsular bag.
    Type: Application
    Filed: May 15, 2003
    Publication date: November 20, 2003
    Inventor: Thomas Terwee
  • Publication number: 20030208265
    Abstract: The present invention is directed to a supplemental endo capsular lens (SECL) and the method of inserting and embedding the SECL within either a gel or polymer, inside the capsule of the crystalline lens, during phaco-ersatz or similar surgical procedures in order to supplement the refractive power of the eye with a view to (1) correcting ametropia while (2) maintaining a useable amplitude of accommodation.
    Type: Application
    Filed: April 4, 2003
    Publication date: November 6, 2003
    Inventors: Arthur Ho, Paul Erickson, Fabrice Manns, Jean-Marie Parel
  • Patent number: 6626538
    Abstract: A method of deriving a prediction model and calculating a predicted lens power to provide a desired post-operative spherical equivalent to correct myopia in a phakic eye of a patient using an intraocular lens includes measuring and determining the predictive significance of certain pre-operative characteristics of the eye, including cycloplegic and manifest spherical equivalent, vertex distance, anterior chamber depth, and keratometry. The prediction model is derived using multiple regression analysis on the pre-operative and post operative data. Measured data corresponding to a particular patient is used in the lens power prediction model to calculate the predicted lens power for implantation in the patient.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: September 30, 2003
    Inventor: Peter N. Arrowsmith
  • Publication number: 20030139809
    Abstract: For attaching an intraocular implant having pincher like clamping arms forming a pinching area between end portions of the clamping arms to an iris of an eye, the implant is positioned against a surface of the iris in the anterior chamber of the eye, a passage in a distal end portion of an ophthalmologic surgical instrument in the anterior chamber of the eye is positioned against a surface portion of the iris closely adjacent the pinching area, and suction is applied to the passage and at least one of the end portions of the clamping arms is urged towards the iris, causing a tuck of iris material adhered to the passage to be inserted into the pinching area. Thus, a tuck adhering to the passage can easily be introduced into the pinching area between the clamping arms. An instrument and an implant specifically adapted for this method are described as well.
    Type: Application
    Filed: January 23, 2002
    Publication date: July 24, 2003
    Inventors: Jan Gerben Frans Worst, Harry Franciscus Simon
  • Patent number: 6582465
    Abstract: An integrated rigid fixation orbital expander has a coupling tunnel, an injection port, and a substantially spherically shaped expansion chamber. The coupling tunnel is configured with opposing side walls, a top wall and a bottom wall. The top wall of the coupling tunnel may have a depression denoting a mid-point of the coupling tunnel and serves as an entry point to introduce a needle for injection. The depression lines up with a hole on the vertical arm of a plate. The plate may glide within the coupling tunnel to align the depression with a desired hole in the plate. The injection port has a floor and a dome and a plurality of channels. The floor of the injection port may have a backstop plate to block a needle from further penetration. The dome of the injection port is connected to the bottom wall of the coupling tunnel.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: June 24, 2003
    Assignee: University of Miami
    Inventor: David T. Tse
  • Publication number: 20030028248
    Abstract: Surgical correction of presbyopia and hyperopia by a circularly distributed assembly of mini-bridges implanted between the interior surfaces of the ciliary muscle and the exterior surface of the lens capsule, for augmenting the transmission of the contraction force of the ciliary muscle/zonule assembly to the lens capsule. The lens is symmetrically squeezed by mini-bridges acting in concert with the ciliary muscle thus changing the curvature of the lens. The mini-bridges are composite synthetic muscles comprising either passive biocompatible mini-bridges made with polymeric gels, silicone polymers or a composite, electromagnetically or mechanically deployable mini-bridges, inflatable balloons or synthetic muscles. The surgical procedure comprises using a ciliary muscle relaxant to stretch the lens/zonules/ciliary muscle assembly.
    Type: Application
    Filed: January 12, 2001
    Publication date: February 6, 2003
    Inventors: Mohsen Shahinpoor, David Soltanpour
  • Publication number: 20030014106
    Abstract: An ophthalmic surgical lens to prevent retinopathy caused by microscopic illumination during cataract or intra-ocular lens surgery. The lens is soft and includes a transparent lens portion placed on a cornea, at least one haptic that extends from the base of the lens portion, and at least one aperture formed by the at least one haptic and the base of the lens portion. The at least one aperture exposes the ocular surface to allow for surgical incisions. The lens portion prevents incisions from being made on the cornea during surgery. The lens also absorbs a patient's corneal refraction so as to prevent the retinopathy.
    Type: Application
    Filed: October 3, 2001
    Publication date: January 16, 2003
    Inventor: Kiyoshi Kita
  • Publication number: 20020169505
    Abstract: The present invention relates to a method for creating shaped implants, such as intraocular lenses in vivo, as well as the novel implants themselves. Utilizing the method of the invention, it is possible to create an implant in vivo and to adjust either the physical properties such as refractive index, viscosity, etc., mechanical properties such as modulus, tensile strength, tear, etc., or the shape of the implant by noninvasive means. For example, using the method of the patent it is possible to create an intraocular lens in vivo and then adjust the shape and power of the lens through no invasion means. The novel implants are also addressed in this application.
    Type: Application
    Filed: March 21, 2002
    Publication date: November 14, 2002
    Inventors: Jagdish M. Jethmalani, Shiao H. Chang, Robert H. Grubbs, Julia A. Kornfield, Daniel M. Schwartz, Christian A. Sandstedt, F. Richard Christ
  • Publication number: 20020161437
    Abstract: Ophthalmic devices suitable for implantation into the eye through small incisions are disclosed. These devices are made from a composition comprising crystalline or semi-crystalline polymeric materials which have a glass transition temperature (Tg) of from about −100° C. to about 20° C., a melting point temperature (Tm) of from about 0° C. to about 37° C., and wherein Tg for the material is lower than Tm for the composition. Disclosed devices include intraocular lenses, corneal inlays, ocular drug delivery devices and implants for reducing intraocular pressure in glaucoma patients; intraocular lenses are preferred.
    Type: Application
    Filed: February 28, 2001
    Publication date: October 31, 2002
    Applicant: Medennium, Inc.
    Inventors: Stephen Q. Zhou, Christopher D. Wilcox, Christine Liau, Igor Valyunin
  • Publication number: 20020138139
    Abstract: The invention discloses methods and apparatus that reverse or eliminate presbyopia by affecting a change in the shape of the sclera. The change can be designed to reduce tension placed on the lens from the zonules, thereby allowing the lens to bulge about its central axis.
    Type: Application
    Filed: March 22, 2002
    Publication date: September 26, 2002
    Inventor: Jonathan S. Till
  • Publication number: 20020133168
    Abstract: Disclosed are an apparatus and method for placing a fluid shunt, for the treatment of glaucoma, from inside the anterior chamber of an eye, through the trabecular meshwork, and into Schlemm's canal. The apparatus can include a handpiece having a distal end and a proximal end; an elongate tip connected to the distal end of said handpiece, the elongate tip having a distal portion and being configured to be placed through a corneal incision and into an anterior chamber of said eye; a holder attached to the distal portion of the elongate tip, the holder configured to hold and release said inlet section of the trabecular shunt; and an actuator on the handpiece that actuates the holder to release the inlet section of the trabecular shunt from the holder.
    Type: Application
    Filed: March 18, 2002
    Publication date: September 19, 2002
    Inventors: Gregory T. Smedley, Morteza Gharib, Hosheng Tu
  • Publication number: 20020120330
    Abstract: The present disclosure relates generally to a refractive anterior chamber ocular implant for placement in the anatomic angle of a phakic eye, the implant having an artificial lens or optic with an anterior surface and a posterior surface and having a haptic for engaging and positioning the optic in the anatomic angle, wherein the haptic possesses in an extension pad that extends and tapers in thickness from the haptic in an axial direction. The disclosure is further directed to methods for correcting refractive errors in a patient in need thereof having a phakic eye and an anatomic angle by surgically implanting an angle supported anterior chamber ocular implant having an optic with the desired refractive properties and a haptic having an extension pad that extends and tapers in thickness from the haptic in an axial direction, and anchoring the extension pad into the anatomic angle of the eye.
    Type: Application
    Filed: February 27, 2001
    Publication date: August 29, 2002
    Inventor: Miles A. Galin
  • Publication number: 20020107567
    Abstract: The present invention relates to a method of manufacturing an intraocular lens inside a capsular bag (28;73) after that the natural lens has been removed and to a sealing device (21;41;61;71) comprising a plug part (23;43;63;77) adapted to seal a rhexis (30;75) in a capsular bag (28;73) and thus preventing displacement through the rhexis (30;75) of a lens-forming liquid material injected through the rhexis (30;75) and adapted to replace the natural lens and form an intraocular lens implant.
    Type: Application
    Filed: November 28, 2001
    Publication date: August 8, 2002
    Inventors: Thomas Terwee, Steven Koopmans
  • Publication number: 20020055778
    Abstract: The present invention relates to polysiloxanes suitable for the preparation of intraocular lenses by a crosslinking reaction, having a specific gravity of greater than about 1.0, a refractive index suitable for restoring the refractive power of the natural crystalline lens and a viscosity suitable for injection through a standard cannula. The present invention includes an injectable intraocular lens material based on said polysiloxanes and methods of preparing intraocular lenses by direct injection into the capsular bag of the eye.
    Type: Application
    Filed: December 10, 2001
    Publication date: May 9, 2002
    Inventors: Peter P. Huo, Stephen Q. Zhou, Christine J. Y. Liau
  • Publication number: 20020045938
    Abstract: An intraocular lens for implantation in an eye comprising an optic configured so that the optic can be deformed to permit the intraocular lens to be passed through an incision into the eye. A peripheral zone circumscribes the optical zone of the optic and one or more fixation members coupled to the peripheral zone and extending outwardly from the peripheral zone to retain the optic in the eye are provided. In one embodiment the fixation member or members are located so that the optical zone is free of such member or members. The peripheral zone preferably has a maximum axial thickness which is larger than the maximum axial thickness of the periphery of the optical zone.
    Type: Application
    Filed: February 18, 2000
    Publication date: April 18, 2002
    Inventors: Daniel G Brady, Christopher Doyle, Bernard F. Grisoni
  • Publication number: 20020042653
    Abstract: A surgically implantable synthetic intraocular lens having a wavelength blocker for blocking transmission of 100% or at least a portion of blue light of wavelengths between about 400 and 510 nanometers, as well as for blocking ultraviolet A and B wavelengths and optionally infrared wavelength transmissions. A preferred wavelength transmission blocker is a tint composition either disposed exteriorly upon the lens or blended interiorly within the lens. Lens utility is found in replacement of the natural crystalline lens to achieve visual correction of aphakia, as well as in correcting refractive errors of the eye through implantation without removal of the natural crystalline lens to thereby provide filtering properties that yield maximum visual acuity along with blockage of untoward wavelength transmissions. The lens implants thereby support vision health by protecting eyes from damage caused through the transmission of untoward wavelengths to the interior of the eye.
    Type: Application
    Filed: December 11, 2001
    Publication date: April 11, 2002
    Inventors: Victor L. Copeland, Steven G. Pratt
  • Publication number: 20020042652
    Abstract: A process for inhibiting vascular proliferation introduces a composition into the eye inducing posterior vitreous detachment. The composition includes a combination of plasminogen, a collagen crosslinking agent and at least one plasminogen activator selected from the group consisting of urokinase, streptokinase, tissue plasminogen activator, chondroitinase, pro-urokinase, retavase, metaloproteinase, and thermolysin. The composition is introduced into the vitreous in an amount effective to induce crosslinking of the vitreous and to induce substantially complete or partial posterior vitreous detachment from the retina without causing inflammation of the retina. In one embodiment, a gaseous material is introduced into the vitreous before or simultaneously with the composition to compress the vitreous against the retina while the composition induces the posterior vitreous detachment.
    Type: Application
    Filed: October 18, 2001
    Publication date: April 11, 2002
    Inventor: Gholam A. Peyman
  • Publication number: 20020035399
    Abstract: The present invention refers to a method of restoring the vision of an eye having an impaired lens with an artificial lens implant. The method involves replacing the lens by a polymerizable material injected into the emptied lens capsule and thereby providing a new lens implant with a predetermined refractive value, while admitting the possibility of controlling and adjusting the refractive value of the eye during the surgical process.
    Type: Application
    Filed: May 24, 2001
    Publication date: March 21, 2002
    Inventors: Thomas Henricus Marie Terwee, Hendrick Albert Weeber, Patricia Ann Piers
  • Patent number: 6342051
    Abstract: A method and implantable device for treating anoxic tissue. A substrate supporting an angiogenesis factor in an amount for treating anoxic tissue is implanted so as to promote revascularization of the tissue. The substrate is a physiologically compatible polymer and may have different configurations such as a fiber, a filament, a microsphere, a needle or a pin. The implantable device may be transported through a catheter or implanted directly in the anoxic tissue. The anoxic tissue may be heart, eye, brain, brain stem, spinal cord, bone and combinations of tissues.
    Type: Grant
    Filed: June 12, 1997
    Date of Patent: January 29, 2002
    Inventor: Gholam A. Peyman
  • Publication number: 20020002402
    Abstract: An integrated rigid fixation orbital expander has a coupling tunnel, an injection port, and a substantially spherically shaped expansion chamber. The coupling tunnel is configured with opposing side walls, a top wall and a bottom wall. The top wall of the coupling tunnel may have a depression denoting a mid-point of the coupling tunnel and serves as an entry point to introduce a needle for injection. The depression lines up with a hole on the vertical arm of a plate. The plate may glide within the coupling tunnel to align the depression with a desired hole in the plate. The injection port has a floor and a dome and a plurality of channels. The floor of the injection port may have a backstop plate to block a needle from further penetration. The dome of the injection port is connected to the bottom wall of the coupling tunnel.
    Type: Application
    Filed: March 23, 2001
    Publication date: January 3, 2002
    Applicant: University of Miami
    Inventor: David T. Tse
  • Publication number: 20010047204
    Abstract: A method for selecting the size of a phakic intraocular lens positioned in the eye between the iris and the natural lens, is disclosed. In this method, the white to white distance of the patient's eye is measured and the length of the lens is based on that measurement. A photographic method of measurement is disclosed.
    Type: Application
    Filed: February 28, 2001
    Publication date: November 29, 2001
    Applicant: Medennium, Inc.
    Inventors: Stephen Q. Zhou, George W. Rozakis
  • Patent number: 6280468
    Abstract: Presbyopia is treated by implanting within a plurality of elongated pockets formed in the tissue of the sclera of the eye transverse to a meridian of the eye, a prosthesis having an elongated body having a first surface and a second surface opposite the first surface to contact the base and flap of the scleral pocket. The first and second surfaces are spaced apart a distance so that the implanted prosthesis exerts an outward force on the flap of the scleral pocket which results in an outward traction on at least the anterior margin of the scleral pocket. The combined effect of the implanted prostheses is to exert a radially outward traction on the sclera in the region overlying the ciliary body which expands the sclera in the affected region together with the underlying ciliary body. The expansion of the ciliary body restores the effective working distance of the ciliary muscle in the presbyopic eye and thereby increases the amplitude of accommodation.
    Type: Grant
    Filed: April 16, 1998
    Date of Patent: August 28, 2001
    Assignee: RAS Holding Corp
    Inventor: Ronald A. Schachar
  • Patent number: 6280469
    Abstract: An implantable artificial iris device which takes the form of a thin, generally annular, single-radially-split wafer, or web, of a bio-compatible, flexible material which can be colored in various ways to replicate the appearance of its predecessor, damaged natural iris. The device permits and encourages a surgical procedure which involves gentle and very simple circular threading (or snaking) of the device circularly longitudinally through a tiny slit created as an incision near the periphery of a cornea. The device is suitable for easy placement within the environment of an eye, either within the region known as the ciliary sulcus or in the region of meeting or joinder of the anterior and posterior capsules and within the realm of the capsular bag.
    Type: Grant
    Filed: May 11, 1999
    Date of Patent: August 28, 2001
    Inventors: Mark A. Terry, Paula J. Ousley