Method Of Implanting Patents (Class 623/902)
  • Patent number: 9486312
    Abstract: A prosthetic valve for implantation in a stenosed aortic valve. The prosthetic valve includes a metallic frame formed with intersecting bars having diameters in the range of 0.1 to 0.6 mm. The frame is radially collapsible for advancement into a native aortic valve using a catheterization technique. The frame is radially expandable for embedding the frame within the native aortic valve. The frame has sufficient radial strength to resist the recoil forces of the native aortic valve after implantation. The prosthetic valve includes a collapsible valvular structure made with pericardium. The prosthetic valve also includes an internal cover which forms a substantially impermeable tubular sleeve. The internal cover preferably extends between a lower extremity of the frame and the valvular structure. The internal cover is preferably sutured to the valvular structure. The valvular structure and internal cover are sutured to the bars of the frame.
    Type: Grant
    Filed: October 21, 2011
    Date of Patent: November 8, 2016
    Assignee: Edwards Lifesciences PVT, Inc.
    Inventors: Brice Letac, Alain Cribier
  • Patent number: 9028548
    Abstract: A prosthesis replaces all or a portion of a natural facet joint on a vertebral body. The prosthesis has a prosthesis body accommodating fixation to the vertebral body at or near a pedicle and without support by a lamina. The prosthesis body has a fastening element installed within the vertebral body at or near a pedicle. The prosthesis further has an artificial facet joint structure carried by the prosthesis body at a location spaced from the fastening element. The artificial facet joint structure is adapted and configured to replace all or a portion of a natural facet joint.
    Type: Grant
    Filed: October 21, 2011
    Date of Patent: May 12, 2015
    Assignee: GMEDELAWARE 2 LLC
    Inventor: Mark A Reiley
  • Patent number: 8986385
    Abstract: An expandable implant for treating bone preferably in a minimally invasive manner includes a preferably cylindrical core element extending along a longitudinal axis and preferably a plurality of nestable, expandable sleeves extending along a longitudinal axis for placement radially about the core element. The plurality of nestable sleeves are sequentially insertable over the core element in such a manner that a first nestable sleeve is inserted over the core element and each subsequently inserted nestable sleeve is received between the core element and the previously inserted nestable sleeve such that the insertion of each additional sleeve causes each previously inserted sleeve to outwardly expand.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: March 24, 2015
    Assignee: DePuy Synthes Products, LLC
    Inventor: Harry Thomas Hall
  • Patent number: 8939145
    Abstract: An apparatus and method for treating sleep apnea and/or snoring is provided. The apparatus includes an appliance sized and structured to be placed in the pharyngeal region of a human or animal and being effective in treating sleep apnea and/or snoring, for example in maintaining openness of an oropharyngeal region of a human or animal during natural sleep, advantageously while not interfering with normal functioning of the epiglottis. Preferably, the appliance is non-circumferential in form and includes rounded, spaced apart end portions.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: January 27, 2015
    Assignee: Quiescence Medical, Inc.
    Inventors: D. Russell Pflueger, Christopher Paul Thompson
  • Patent number: 8808378
    Abstract: A prosthesis replaces all or a portion of a natural facet joint on a vertebral body. The prosthesis has a prosthesis body accommodating fixation to the vertebral body at or near a pedicle and without support by a lamina. The prosthesis body has a fastening element installed within the vertebral body at or near a pedicle. The prosthesis further has an artificial facet joint structure carried by the prosthesis body at a location spaced from the fastening element. The artificial facet joint structure is adapted and configured to replace all or a portion of a natural facet joint.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: August 19, 2014
    Assignee: GMEDELAWARE 2 LLC
    Inventor: Mark A Reiley
  • Patent number: 8685427
    Abstract: A medical device for placement in a body of a mammal is provided. The medical device comprises (1) a polymeric matrix forming the device and defining a lumen through the device, the matrix comprising polymer macromolecules and defining spaces between the polymer macromolecules; (2) a drug contained within at least some of the spaces of the matrix; and (3) a material contained within at least some of the spaces of the matrix to affect diffusion of the drug out of the polymeric matrix when the medical device is placed in the body of the mammal.
    Type: Grant
    Filed: July 31, 2002
    Date of Patent: April 1, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Jianmin Li, Weenna Bucay Couto
  • Patent number: 8470049
    Abstract: A femoral prosthesis. The femoral prosthesis includes an implant body having a proximal end and a distal end and a shoulder at the proximal end, the shoulder being structured and dimensioned for a tight press fit into the neck of a femur. The implant body includes a trunk at the distal end, the trunk having a wedge formed by a tapered portion extending in the direction of the distal end of the implant body. The implant body also includes a medial column extending from the shoulder toward the distal end and a lateral column extending from the shoulder toward the distal end. The wedge, the medial column, and the lateral column to provide multi-planar stability for the implant body and surface area for fixation of the implant body.
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: June 25, 2013
    Assignee: Concept, Design and Development, LLC
    Inventors: Bradley Walter, Declan Brazil, Timothy McTighe
  • Patent number: 8398719
    Abstract: A femoral prosthesis. The femoral prosthesis includes an implant body having a proximal end and a distal end and a shoulder at the proximal end, the shoulder being structured and dimensioned for a tight press fit into the neck of a femur. The implant body includes a trunk at the distal end, the trunk having a wedge formed by a tapered portion extending in the direction of the distal end of the implant body. The implant body also includes a medial column extending from the shoulder toward the distal end and a lateral column extending from the shoulder toward the distal end. The wedge, the medial column, and the lateral column to provide multi-planar stability for the implant body and surface area for fixation of the implant body.
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: March 19, 2013
    Assignee: Concept, Design and Development, LLC
    Inventors: Bradley Walter, Declan Brazil, Timothy McTighe
  • Patent number: 8343212
    Abstract: A medical device, for example a stent, has a surface which in use contacts body tissue, wherein said surface has on it a biocompatible coating layer comprising a polymer having covalently bound allyl-terminated pendent groups, said pendent groups comprising a moiety selected from -0-CH2—CH?CH2—S—CH2—CH?CH2—S(=0)-CH2—CH?CH2—Se—CH2—CH?CH2 and —Se (=0 J-CH2—CH?CH2. This surface has good biocompatibility and can bind strongly to a metallic surface. The polymer may be made from an electropolymerisable monomer, e.g. a pyrrole.
    Type: Grant
    Filed: May 15, 2008
    Date of Patent: January 1, 2013
    Assignee: Biotectix, LLC
    Inventors: Christopher John Pickett, Timothy James Boote, Saad Khalil Ibrahim, Jane Marie Knott, John Douglas Tolland
  • Patent number: 8340379
    Abstract: Presented herein are methods, systems, and computer-readable medium for presenting imaging data related to an anatomical site. These include obtaining a first set of imaging data related to the anatomical site and tracking units at the anatomical site and, thereafter, optionally, obtaining a second set of imaging data related to the anatomical site. A deformed version of the first set of imaging data is then determined based on the relative arrangements of one or more of the tracking units at the time when the first set of imaging data is obtained and when the second set of imaging data is obtained. Then the relative emplacements of the second set of imaging data set and of the deformed version of the first set of imaging data set are determined and used, along with the second set of imaging data set and the deformed version of the first set of imaging data, as a basis for displaying image guidance data.
    Type: Grant
    Filed: March 6, 2009
    Date of Patent: December 25, 2012
    Assignee: Inneroptic Technology, Inc.
    Inventors: Sharif Razzaque, Andrei State
  • Patent number: 8160678
    Abstract: A method for repairing or modifying an area of a patient's anatomy that comprises directing at least a portion of a scanning beam assembly to an area of a patient's anatomy, applying a radiation-responsive agent to portion of the anatomy, and exposing the radiation-responsive agent to radiation directed onto the agent by the reflector to cause the agent to therapeutically interact with the site. The scanning beam assembly including a radiation source capable of emitting radiation, a reflector that receives the radiation from the radiation source to direct the radiation onto the anatomy, wherein the reflector oscillates in at least two directions to create a scan of the anatomy, a detector to detect radiation returned from the anatomy, and a controller to convert the detected radiation into a displayable anatomy image.
    Type: Grant
    Filed: June 18, 2007
    Date of Patent: April 17, 2012
    Assignee: Ethicon Endo-Surgery, Inc.
    Inventors: Michael S. Cropper, Thomas W. Huitema, Michael P. Weir, Robert J. Dunki-Jacobs, Jere J. Brophy, Robert M. Trusty, Randal T. Byrum, David C. Youmans, Sean P. Conlon, Gary L. Long, Paul G. Ritchie, Jane A. Sheetz
  • Patent number: 8057396
    Abstract: Devices for assessing the size, shape, and topography of vessel lumens and hollow portions of organs are described. The devices are particularly adapted for determining the size, shape, topography, and compliance of the native heart valves to facilitate the later implantation of a prosthetic heart valve. The devices are typically catheter-based having an assessment mechanism fixed to a distal end of the catheter. The assessment mechanism generally includes an expandable member, such as a balloon. The assessment mechanism may also include an imaging member, a physical assessment member, an electronic mapping construction, an alignment mechanism, a valvuloplasty balloon, or any combination thereof.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: November 15, 2011
    Assignee: Phoenix Biomedical, Inc.
    Inventors: David C. Forster, Brian Beckey, Brandon Walsh, Scott Heneveld
  • Patent number: 7992566
    Abstract: An apparatus and methods for treating sleep apnea and/or snoring are provided. The apparatus includes an appliance sized and structured to be placed in the pharyngeal region of a human or animal. The appliance, when so placed is effective in treating sleep apnea and/or snoring, for example in maintaining openness of an oropharyngeal region of a human or animal during natural sleep. Preferably, the appliance is non-circumferential in form and includes rounded, spaced apart end portions.
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: August 9, 2011
    Assignee: Quiescence Medical, Inc.
    Inventors: D. Russell Pflueger, Christopher Paul Thompson
  • Patent number: 7963992
    Abstract: The present invention provides methods and devices for treating the annulus of an intervertebral disc. The methods and devices can employ an expandable treatment device which is deployed at least partially in the subannular space. Fixation devices and methods are also disclosed, which help to secure the treatment device in place.
    Type: Grant
    Filed: October 8, 2008
    Date of Patent: June 21, 2011
    Assignee: Anulex Technologies, Inc.
    Inventors: Joseph C. Cauthen, III, Matthew M. Burns, Lawrence W. Wales, Brian L. Dukart, Bradley J. Wessman, Rodney L. Houfburg, Ishmael Bentley
  • Patent number: 7951201
    Abstract: The present invention provides methods and devices for treating the annulus of an intervertebral disc. The methods and devices employ a fixation device delivery tool having a curved body portion. Fixation devices and methods are also disclosed for placement in intervertebral disc tissue.
    Type: Grant
    Filed: January 12, 2007
    Date of Patent: May 31, 2011
    Assignee: Anulex Technologies, Inc.
    Inventors: Joseph C. Cauthen, Matthew M. Burns, Lawrence W. Wales, Rodney L. Houfburg, Joseph D. Farrell
  • Patent number: 7909868
    Abstract: A gel cap is loaded on a folded flange of a voice prosthesis which is loaded on an end portion of an inserter, wherein a tip of the end portion is pressed against a valve flap of the voice prosthesis. The voice prosthesis includes a strap that is stretched for engagement with an attachment portion on the inserter. The voice prosthesis, gel cap, and inserter are inserted into the tracheoesophageal puncture. The patient then swallows fluids to cause the gel cap to dissolve to allow the esophageal flange to deploy, whereby upon deployment of the esophageal flange, the tip of the end portion of the inserter presses the valve flap open, allowing the inserter to move axially relative to the voice prosthesis until a stop collar of the inserter engages the voice prosthesis providing external visual confirmation to the user that the gel cap has dissolved and the esophageal flange has deployed.
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: March 22, 2011
    Assignee: Helix Medical, LLC
    Inventor: Eric D. Blom
  • Patent number: 7879102
    Abstract: A minimally invasive spinal disc defect repair method is disclosed. The method relates to insertion of disc defect repair materials that are substantially two-dimensionally shaped and which allow for insertion and preferably self retention within the disc defect with plugging of the annulus fibrosis.
    Type: Grant
    Filed: September 30, 2003
    Date of Patent: February 1, 2011
    Assignee: Depuy Acromed, Inc.
    Inventors: Michael Slivka, Hassan Serhan
  • Patent number: 7749273
    Abstract: The present invention provides methods and devices for treating the annulus of an intervertebral disc. The methods and devices can employ an expandable treatment device which is deployed at least partially in the subannular space. Fixation devices and methods are also disclosed, which help to secure the treatment device in place.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: July 6, 2010
    Assignee: Anulex Technologies, Inc.
    Inventors: Joseph C. Cauthen, III, Matthew M. Burns, Lawrence W. Wales, Brian L. Dukart, Bradley J. Wessman, Rodney L. Houfburg, Ishmael Bentley
  • Patent number: 7670380
    Abstract: A stent, or device for repair and reconstruction of the spinal disc wall, or annulus fibrosus, after surgical incision or pathologic rupture, which is inserted through an aperture into the subannular space. The stent has radial extensions which are caused or allowed to expand into an expanded configuration to bridge the aperture. The stent thereby occludes the defective region from the inside of the vertebral disc and prevents the migration of nucleus pulposus therethrough, while also providing a scaffold for tissue growth.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: March 2, 2010
    Assignee: Anulex Technologies, Inc.
    Inventor: Joseph C. Cauthen, III
  • Patent number: 7670379
    Abstract: A stent, or device for repair and reconstruction of the spinal disc wall, or annulus fibrosus, after surgical incision or pathologic rupture, which is inserted through an aperture into the subannular space. The stent has radial extensions which are caused or allowed to expand into an expanded configuration to bridge the aperture. The stent thereby occludes the defective region from the inside of the vertebral disc and prevents the migration of nucleus pulposus therethrough, while also providing a scaffold for tissue growth.
    Type: Grant
    Filed: February 16, 2006
    Date of Patent: March 2, 2010
    Assignee: Anulex Technologies, Inc.
    Inventor: Joseph C. Cauthen
  • Patent number: 7491180
    Abstract: A method of determining the size and/or placement of a prosthetic disc in a disc space between adjacent endplates of two vertebrae in a selected spinal area, comprising: using a computer to identify the disc space parameters of height, width, depth and lordosis between the adjacent vertebral endplates; using a computer to create an artificial volume corresponding to an actual prosthetic disc that can be positioned in the disc space in accordance with a manufacturer's size and lordosis specifications for prosthesis; using a computer to determine the center of the disc space and the center of rotation of the prosthetic disc volume; using a computer to position the prosthetic disc volume in the disc space such that the center of rotation of the prosthetic disc volume is positioned posterior to the center of the disc space; and using a computer to determine the prosthetic disc volume that fits within the disc space in accordance with a surgeon's or manufacturer's specification for prosthesis.
    Type: Grant
    Filed: June 27, 2007
    Date of Patent: February 17, 2009
    Inventor: Hector O. Pacheco
  • Patent number: 7172625
    Abstract: Suturing rings and methods of use thereof facilitating initial implantation of new and replacement of dysfunctional tissue or mechanical heart valve mechanisms supported by the suturing ring are disclosed. The suturing ring annulus is adjustable to receive and engage the valve frame of the heart valve mechanism within the annulus. An interlocking mechanism applies restraint to fix the adjusted suturing ring annulus engaged against the valve frame to support the heart valve mechanism during chronic implantation. Sutures affixing the suturing ring to the valvar rim can be routed and entrapped between the suturing ring annulus and the valve frame when the suturing ring is restraint is applied. The restraint is released to replace a dysfunctional heart valve mechanism and reapplied when a new heart valve mechanism is fitted into the annulus.
    Type: Grant
    Filed: July 16, 2002
    Date of Patent: February 6, 2007
    Assignee: Medtronic, Inc.
    Inventors: Mark C. S. Shu, Luis A. Salazar
  • Patent number: 7100617
    Abstract: Minimally invasive techniques utilized in bypass grafting are disclosed. For instance, a method of implanting an end portion of a graft in the body of a patient during a bypass grafting procedure includes the steps of (i) advancing a medical instrument within a circulatory system of said body, (ii) guiding a distal end of said medical instrument out of said circulatory system through an opening defined in said circulatory system after said medical instrument advancing step, (iii) advancing said end portion of said graft within said medical instrument after said guiding step, and (iv) securing said end portion of said graft to a blood vessel of said circulatory system after said end portion advancing step.
    Type: Grant
    Filed: December 2, 2003
    Date of Patent: September 5, 2006
    Assignee: CardioThoracic Systems, Inc.
    Inventor: Thomas J. Maginot
  • Patent number: 7087084
    Abstract: A prosthesis replaces all or a portion of a natural facet joint on a vertebral body. The prosthesis has a prosthesis body that accommodates fixation to the vertebral body at or near a pedicle and without support by a lamina. The prosthesis also has an artificial facet joint structure carried by the prosthesis body. The artificial facet joint structure is adapted and configured to replace all or a portion of a natural facet joint.
    Type: Grant
    Filed: September 9, 2003
    Date of Patent: August 8, 2006
    Assignee: Archus Orthopedics, Inc.
    Inventor: Mark A Reiley
  • Patent number: 7063722
    Abstract: A method of implanting a resilient self-molding annuloplasty ring including stretching it to an expanded diameter and attaching it to a heart valve annulus, then permitting the ring to contract to reduce the diameter of the annulus. The ring may be positioned on an insertion device that maintains the ring in its expanded diameter while attaching to the annulus. The resilient self molding annuloplasty ring which may be enlarged prior to implantation to facilitate implantation within a dilated or otherwise incompetent valve annulus having sufficient contractive force to render a valve competent. The self molding annuloplasty ring of the invention may further comprise integral attachment devices to aid in the implantation process.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: June 20, 2006
    Assignee: Edwards Lifesciences, LLC
    Inventor: Salvador Marquez
  • Patent number: 7052516
    Abstract: A spinal disc annulus repair stent for repair and reconstruction of the spinal disc wall (annulus) after surgical invasion or pathologic rupture, which may incorporate suture closure or other means of stent insertion and fixation, designed to reduce the failure rate of conventional surgical procedures on the spinal discs. In an illustrative embodiment, the design of the spinal disc annulus stent advantageously allows ingrowth of normal cells of healing in an enhanced fashion strengthening the normal reparative process.
    Type: Grant
    Filed: April 29, 2002
    Date of Patent: May 30, 2006
    Assignee: Anulex Technologies, Inc.
    Inventors: Joseph C. Cauthen, III, Matthew M. Burns, Thomas R. Hektner, Paul Burmeister, Lawrence W. Wales, Daniel O. Adams, Rodney L. Houfburg
  • Patent number: 7044964
    Abstract: A catheter system has a balloon angioplasty device disposed about a common lumen near its distal end. The balloon catheter is pre-fitted with a stent which is deployed when the balloon is inflated. The common lumen is in communication with multiple lumens within a proximal region of the catheter body to allow for positioning of the catheter over a movable guide wire and convenient delivery of imaging or interventional devices to a desired region of a body passageway being treated. The procedure for stent deployment optionally includes steps of imaging a lumen by ultrasound before and after stent deployment to identify the site at which a stent is needed, to confirm that the stent is being and has been deployed at a longitudinal position which does not overlap a branched segment of the body passageway, and to ensure that the stent has been radially opened to an optimum diameter.
    Type: Grant
    Filed: November 27, 2002
    Date of Patent: May 16, 2006
    Assignee: Cardiovascular Imaging Systems, Inc.
    Inventors: Yue-Teh Jang, Stephen M. Salmon, David A. White, Rizza A. Garcia
  • Patent number: 7033395
    Abstract: A surgical method of repair and reconstruction of the spinal disc wall (annulus) after surgical invasion or pathologic rupture, incorporating suture closure, or stent insertion and fixation, designed to reduce the failure rate of conventional surgical procedures on the spinal discs. The design of the spinal disc annulus stent allows ingrowth of normal cells of healing in an enhanced fashion strengthening the normal reparative process.
    Type: Grant
    Filed: March 19, 2003
    Date of Patent: April 25, 2006
    Assignee: Anulex Technologies, Inc.
    Inventor: Joseph C. Cauthen
  • Patent number: 7001429
    Abstract: A method of securing soft tissue to a prosthesis that has a retaining member secured thereto is disclosed. The method includes looping a first end portion of a first band around the retaining member such that both the first end portion of the first band and a second end portion of the first band extend outwardly from the retaining member. The method further includes looping a first end portion of a second band around the retaining member such that both the first end portion of the second band and a second end portion of the second band extend outwardly from the retaining member. Moreover, the method includes securing the soft tissue to (i) the first end portion and the second end portion of the first band, and (ii) the first end portion and the second end portion of the second band.
    Type: Grant
    Filed: June 17, 2003
    Date of Patent: February 21, 2006
    Assignee: DePuy Orthopaedics, Inc.
    Inventor: Joe W. Ferguson
  • Patent number: 6997956
    Abstract: A surgical method of repair and reconstruction of the spinal disc wall (annulus) after surgical invasion or pathologic rupture, incorporating suture closure, or stent insertion and fixation, designed to reduce the failure rate of conventional surgical procedures on the spinal discs. The design of the spinal disc annulus stent allows ingrowth of normal cells of healing in an enhanced fashion strengthening the normal reparative process.
    Type: Grant
    Filed: March 19, 2003
    Date of Patent: February 14, 2006
    Assignee: Anulex Technologies, Inc.
    Inventor: Joseph C. Cauthen
  • Patent number: 6984247
    Abstract: A surgical method of repair and reconstruction of the spinal disc wall (annulus) after surgical invasion or pathologic rupture, incorporating suture closure, or stent insertion and fixation, designed to reduce the failure rate of conventional surgical procedures on the spinal discs. The design of the spinal disc annulus stent allows ingrowth of normal cells of healing in an enhanced fashion strengthening the normal reparative process.
    Type: Grant
    Filed: February 12, 2003
    Date of Patent: January 10, 2006
    Assignee: Anulex Technologies, Inc.
    Inventor: Joseph C. Cauthen
  • Patent number: 6946003
    Abstract: Biocompatible, implantable material comprising flexible, elongate tape and a plurality of elongate elements, each elongate element being aligned along and independently translatable in the longitudinal direction of the tape; implants manufactured from this material, for the partial or total replacement or reinforcement of connective tissue such as ligament, cartilage, bone, meniscus tendon, skin.
    Type: Grant
    Filed: May 22, 2000
    Date of Patent: September 20, 2005
    Assignee: Smith & Nephew plc
    Inventors: Sorrel Wolowacz, Nicholas John Cotton
  • Publication number: 20040267358
    Abstract: An implant for treating insufficiency of a heart valve, in particular of the mitral valve, has an elongate body which can be converted from a first, substantially elongated and substantially flexible state to a second state with a reduced bending radius. The implant also has a flexible tensioning element extending along the body for the purpose of converting the body from the first state to the second state. The body is made up of a plurality of elements which are arranged in series to form a chain and which, in the first state, are movable relative to one another. In the second state of the body, the tensioning element tensions the elements with respect to one another so as form an arc, said elements being substantially immovable relative to one another in the second state and forming, on an internal radius face of the arc, a substantially continuous planar support surface.
    Type: Application
    Filed: June 10, 2004
    Publication date: December 30, 2004
    Inventor: Oyvind Reitan
  • Publication number: 20040249453
    Abstract: A method for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural orifice or lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like.
    Type: Application
    Filed: August 29, 2003
    Publication date: December 9, 2004
    Inventors: Richard G. Cartledge, Leonard Y. Lee
  • Publication number: 20040225373
    Abstract: Endoluminally delivered tissue patches and related systems and methods for delivering the tissue patches for treating lesions of the alimentary tract are disclosed. A tissue patch includes a tissue implant imbedded in a substrate to form a first layer and a second layer of substrate on a top surface and a bottom surface of the tissue implant. A predetermined thickness of the first layer is different from a predetermined thickness of the second layer. A tissue patch may include a tissue implant imbedded in a substrate formed of a plurality of sections capable of being folded into a contracted state for endoluminal delivery to the lesion. A system for delivering a tissue implant includes a catheter having an expandable member at a distal end portion, a carrier placed around the expandable member, and the carrier configured to expand from a contracted state to an expanded state and to receive the tissue implant.
    Type: Application
    Filed: May 5, 2003
    Publication date: November 11, 2004
    Applicant: Scimed Life Systems, Inc.
    Inventors: Charles H. Pugsley, Marcia McBride-Sakal
  • Patent number: 6814737
    Abstract: A spinal implant insertion instrument for intervertebral implant surgery formed from a hollow first element of various external diameters, including a channel to accommodate and incorporate a vertebral pedicle, and a second element joined by a hinge to the first element, allowing reduction of the external diameter of the leading edge of the spinal implant insertion element sufficient to allow the passage of the spinal implant insertion instrument into the intervertebral disc space in a safe fashion, as the first maneuver, to be followed by activation of the second element upon the first, restoring the internal diameter of the spinal implant insertion instrument to a sufficient radius to allow successive passage of cutting, reaming, tapping instruments, and subsequent implantation of a spinal interbody implant device.
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: November 9, 2004
    Assignee: Cauthen Research Group, Inc.
    Inventor: Joseph C. Cauthen
  • Publication number: 20040220296
    Abstract: Thermogelling polymers are described containing poly (n-isopropyl acrylamide). Solutions of this polymer, copolymers or mixtures of the polymer with a second polymer such as poly(ethylene glycol), poly (vinyl pyrrolidone) or poly(vinyl alcohol) are liquids at room temperature and solids at body temperature. Thus, also provided are methods of implanting a hydrogel into a mammal by injecting the solution as a liquid at a temperature below body temperature into a selected site in the mammal at a temperature below body temperature, which then undergoes thermal phase transition to form a solid hydrogel in situ in the body as the implant warms to body temperature. Methods for using these thermal gelling materials in various applications including nucleus pulposus replacement/augmentation, wound care, disk replacement, cartilage replacement, joint replacement, surgical barriers, gastrointestinal devices, cosmetic and reconstructive surgery, and breast enlargement are also provided.
    Type: Application
    Filed: April 30, 2004
    Publication date: November 4, 2004
    Inventors: Anthony M. Lowman, Michele S. Marcolongo, Alastair J.T. Clemow
  • Publication number: 20040187877
    Abstract: A method for inducing the repair of damaged or diseased liver tissue in vivo is provided. The method comprises the step of administering to the patient a graft composition comprising basement membrane tissue of a warm-blooded vertebrate in an amount effective to induce the repair of the liver tissue at the site of administration of the graft composition.
    Type: Application
    Filed: December 4, 2003
    Publication date: September 30, 2004
    Inventors: Stephen F. Badylak, Sangeeta N. Bhatia
  • Publication number: 20040181149
    Abstract: The invention relates to a device for intraoperative navigation and placing of a medical implant, in particular, a prosthesis, using a mobile medical imaging device A) a position determination device (15) for the spatial position measurement of the reference elements (1) relative to a spatially-fixed coordinate system (13); B) a mobile medical imaging device (3), comprising a radiation source (10) and a receiver unit (11), C) a computer (6) connected to the position determination device (15) and comprising a screen (7) whereby D) radiation source (10) and receiver unit (11) are connected to an imaging unit (18), which may be displaced about the room in a manner as to be fixed relative to each other and E) a reference element (1) is fixed to each of the imaging device (18), the bones (2) for treatment, and the surgical instrument (14).
    Type: Application
    Filed: April 29, 2004
    Publication date: September 16, 2004
    Inventors: Ulrich Langlotz, Lutz-Peter Nolte
  • Patent number: 6786904
    Abstract: A method and device to treat cardiovascular vulnerable plaque is provided by heating an implanted structure placed adjacent to a vulnerable plaque tissue to conduct heat into the vulnerable plaque tissue for a period of time. In a preferred embodiment, the implanted structure is a stent-like structure (SLS), and the heating of the implanted structure is a non-invasive inductive heating. The detecting of the vulnerable plaque tissue can be accomplished by techniques, such as Magnetic Resonance Imaging (MRI), infrared spectroscopy, thermography, blood tests, ultrasound, and X-ray, etc.
    Type: Grant
    Filed: January 10, 2002
    Date of Patent: September 7, 2004
    Assignee: Triton BioSystems, Inc.
    Inventors: Claas Döscher, Wolfgang Daum
  • Patent number: 6769434
    Abstract: A method for deploying an aortic valve prosthesis includes the steps of: making a first opening leading to the left atrium; passing the valve prosthesis through the opening and into a cardiac chamber of the left side of the heart using a first manipulation instrument; making a second opening in the arterial system and advancing one end of a second manipulation instrument through the arterial opening and into the cardiac chamber; securing the second manipulation instrument to the valve prosthesis; and using the second manipulation instrument to retract at least a portion of the valve prosthesis out of the cardiac chamber.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: August 3, 2004
    Assignee: Viacor, Inc.
    Inventors: John R. Liddicoat, Gregory H. Lambrecht, Todd F. Davenport, William E. Cohn, Steven B. Woolfson, Daniel C. Taylor
  • Publication number: 20040148035
    Abstract: Disclosed is an apparatus for deploying a bronchial isolation device in a bronchial passageway in a lung of a patient. In one embodiment, the apparatus includes an outer shaft having a distal end. A housing is coupled to the distal end of the outer shaft and configured to receive the bronchial device. An inner shaft is slidably disposed within the outer shaft. A handle is adapted to move the outer shaft relative to both the inner shaft and the handle while the inner shaft remains fixed relative to the handle so as to eject the bronchial isolation device from the housing.
    Type: Application
    Filed: November 25, 2003
    Publication date: July 29, 2004
    Inventors: Michael Barrett, David Tholfsen, Michael Hendricksen, Ronald Hundertmark, John McCutcheon, Antony J. Fields, Jeffery J. Dolin, Robert M. George
  • Publication number: 20040127979
    Abstract: A device and method for improving flow through a native blood vessel valve, such as the aortic valve, are provided. The present invention allows a miniature valve to be implanted into affected leaflets percutaneously, obviating the need for coronary bypass surgery. The method includes the cutting of small holes, on the order of 4 mm, in the leaflets of a targeted valve, thereby allowing blood to flow through the newly formed holes. The holes are used as attachment sites for the miniature valves of the present invention.
    Type: Application
    Filed: August 28, 2003
    Publication date: July 1, 2004
    Applicant: HEART LEAFLET TECHNOLOGIES, INC
    Inventors: Robert Foster Wilson, Scott Robert Wilson, James L. Pokorney
  • Publication number: 20040117033
    Abstract: This invention is a method for the implantation of a combination of cells or cell-microcarrier aggregates wherein one component comprises a solid implantable construct and a second component comprises an injectable formulation. For example, in one embodiment, the solid implant may be first implanted to fill the majority of the cavity receiving the implant, and then cells or cell-microcarrier aggregates in an injectable format, with or without the addition of gelling materials to promote rapid gelling in situ, may be injected into spaces surrounding the solid implant in order to secure the solid implant in the site and/or to promote rapid adherence and/or integration of the solid implant to surrounding tissues. Also contemplated in this embodiment is that the cellular composition of the injectable component may differ from that of the solid component.
    Type: Application
    Filed: December 9, 2003
    Publication date: June 17, 2004
    Inventors: Carmelita G. Frondoza, David S. Hungerford, Alan H. Shikani, Abraham J. Domb, David J. Fink, Leonard Bloom
  • Publication number: 20040110722
    Abstract: The present invention relates to hyaluronic acid polymers modified with non-proteinaceous catalysts for the dismutation of superoxide, and processes for making such materials. The invention further provides pharmaceutical compositions comprising the modified biopolymer and therapeutic methods comprising administering the modified biopolymer to a subject in need thereof.
    Type: Application
    Filed: November 5, 2003
    Publication date: June 10, 2004
    Inventors: Richard L. Ornberg, Kishore Udipi, Denis Forster, Dennis P. Riley, Kenneth B. Thurmond, Susan Henke, Kerry Brethauer, Saikat Joardar
  • Patent number: 6719801
    Abstract: Disclosed are a prosthesis configuration and method for treating acquired flatfoot. In an exemplary embodiment of the invention, a member is positioned between a first bone in the foot and a second bone in the foot, such that the first and second bones are separated by a third bone, and a maximum force in the member is a tension force when the foot is under a standing load. The member is longitudinal and flexible.
    Type: Grant
    Filed: December 28, 2001
    Date of Patent: April 13, 2004
    Inventor: Edward S. Holt
  • Publication number: 20040030408
    Abstract: The present invention provides a medical implant material comprising mammalian transglutaminase and a polymer, wherein the transglutaminase is provided in the absence of free divalent metal ions and wherein the polymer is associated with the transglutaminase binding protein. Preferably, the transglutaminase is a tissue transglutaminase, which is coated on, impregnated into or covalently linked to the polymer. The polymer may be naturally occuring or synthetic, and may be biodegradable or non-biodegradable. The medical implant material may further comprise a reinforcing agent and/or one or more additional polymers. The invention further provides the use of a mammalian transglutaminase in a method for improving the biocompatibility of a medical implant material, the method comprising the steps of (i) providing a medical implant material comprising a polymer associated with a binding protein for binding the transglutaminase, and (ii) treating said material with a mammalian transglutaminase.
    Type: Application
    Filed: July 9, 2003
    Publication date: February 12, 2004
    Inventors: Martin Griffin, Deborah Heath, Paul Christian
  • Publication number: 20040019387
    Abstract: The present invention relates to laryngotracheal devices and methods of use thereof in surgical procedures. In particular, the invention relates to the uses of laryngotracheal devices to treat subglottic stenoses.
    Type: Application
    Filed: May 19, 2003
    Publication date: January 29, 2004
    Inventors: Philippe Monnier, Rene Gilliard
  • Publication number: 20040010317
    Abstract: A vertebral disc prosthesis, a method of implanting a prosthesis and a deployment device is provided. The prosthesis may be implanted into the interior region of the vertebral disc so as to displace existing vertebral tissue, such as NP. The size or amount of the prosthesis inserted into the interior region of the vertebral disc may be a characteristic of the disc or the prosthesis. For example, the amount or size of prosthesis inserted into the disc may be dependent upon restoring the functionality of the disc (e.g., the ability of the disc to transfer nutrients or otherwise survive, the ability of the disc to carry the required loads and absorb stress or the reduction of pain). Restoring disc function may be determined by the resulting disc height desired, the resulting disc pressure desired or the resulting disc volume desired. The prosthesis may be sized or positioned within the interior of the vertebral disc such that it is spaced from at least one of the end plates of the vertebral disc.
    Type: Application
    Filed: May 7, 2003
    Publication date: January 15, 2004
    Inventors: Gregory Lambrecht, Jason Partin, Sean Kavanaugh, Jacob Einhorn
  • Patent number: 6676694
    Abstract: A first catheter has a return bend formed near its distal free end and a first magnet is mounted on the distal free end. The first catheter is introduced through a sheath in a first common femoral artery into an elongate leg of a stent graft and pulled back until the return bend positions the first magnet near a truncate leg of the stent graft. A second catheter having a second magnet on its distal free end is introduced through a second common femoral artery and positioned near the first magnet so that the magnets become interconnected. The second catheter is pulled into the stent graft, a guide wire is inserted through it, and a second sheath is introduced into the stent graft. A contralateral limb is deployed through the second sheath and the second sheath is removed. In another embodiment, catheters with magnets pull a nephroureteral stent from a kidney.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: January 13, 2004
    Inventor: Mitchell Weiss