Abstract: Exemplary embodiments of the inventive concept are directed to devices for facilitating the creation of pathology cell blocks and to methods for creating such cell blocks using said devices. Various cell block preparation devices are described, which cell blocks may be comprised of various media and may be provided with one or multiple wells for receiving and retaining tissue/cell specimens, such as cytology specimens. The tissue/cell specimen laden cell block preparation devices are treated with fixative to produce cell block specimens that are highly amenable to sectioning and subsequent analysis according to known methods. A marker may be integrated into any of the cell block preparation devices to guide a technologist during sectioning and subsequent application of cell block sections to slides for proper orientation of the cell block sections.

Abstract: A biologic sample preparation system that prepares samples for processing includes a frame defining a horizontal plane, a pipette assembly, a sample module and an extraction module. The pipette assembly includes a first pipette. The pipette assembly is movably mounted to the frame in a direction substantially perpendicular to the horizontal plane during operation. The sample module includes a sample plate and is movably mounted to the frame. The sample module is movable substantially parallel to the horizontal plane at least from a sample area spaced from the pipette assembly and a working area proximate the pipette assembly. The extraction module includes an extraction plate and is movably mounted to the frame. The extraction module is movable substantially parallel to the horizontal plane at least from an extraction staging area spaced from the pipette, assembly and the working area proximate the pipette assembly.

Abstract: The present invention relates to method for assessing the H2S release capacity of a liquid sample containing one or more sulfur compounds which are able to be degraded into gaseous H2S with temperature. The method comprising: a) Placing a volume of the liquid sample in a purge vessel so as to obtain a liquid phase and a gaseous phase in a flask; b) Purging the gaseous phase with an inert gas stream for a determined period of time; e) Passing the purged gaseous phase through a H2S trap; d) Recovering H2S from the H2S trap; and e) Dosing the recovered H2S. The invention is also used in a method for selecting a liquid sample, in particular among a group of different liquid samples.

Abstract: The invention concerns a frame (1) for holding a plurality of filtration assemblies (100) and a testing unit (10) for microbiological testing. The frame (1) for holding the plurality of filtration assemblies (100) comprises an array of supports (5) each configured to receive and support one of the filtration assemblies (100) on a common support plane (2), and connection means (6) provided on the periphery (7) of the frame (1) and configured to releasably connect, by a form-locking engagement, a further frame (1) such that the common support planes (2) of the connected frames (1) are contiguous. Further, the testing unit (10) comprises at least one frame (1) packed in a bag (20) in pre-sterilized condition.

Abstract: An automatic pipette system is provided which includes a module body, said body including a stationary contact surface, and an ejection assembly, including a mount for a pipette tip, and a motor, located within the module body and configured to: dispense liquid by actuating a piston in a cylinder, and to move the ejector assembly in a first direction in such a manner that the pipette tip contacts the contact surface and disengages from the mount.

Abstract: An improved device for collecting particulate matter suspended in the ambient air is disclosed comprising a container extending between an open first end and a closed second end defining a container interior. A container output communicates with a container interior located proximate the closed second end of the container. A filter cassette comprising a collection filter is permanently affixed to a filter holder. A retainer having a retainer input retains the filter cassette between the retainer input and the container output. An output connector connects the container output to a low pressure source for drawing ambient air into the retainer input for enabling the collection filter to collect particulate matter suspended in the ambient air entering the retainer input. Preferably, the filter holder and the filter are disposable.

Abstract: A non-contact aerodynamic sampling tool for collecting particles and vapors from the surfaces. Opposing planar jets or planar jet arrays are used to liberate material from surfaces so that particulate matter and vapors can be collected for analysis in real time. High-speed valves may be triggered to create pressure waveforms for high velocity pressurized planar jet bursts, or continuously operated opposing wall jets may be angularly directed toward a target surface, permitting sampling from large standoff distances. The wall jets traverse the surface and exhibit significant drag forces to lift particles into a suction intake. Unlike axisymmetric jets, the wall jets sustain the flow momentum over the target surface for a greater distance, dislodging particles submerged in the boundary layer and significantly improving particle resuspension and vapor collection.

Abstract: Analytical instruments are provided that can include a sample inlet component with the sample inlet component including a first sampling port; a plurality of sample capturing assemblies; and a first valve assembly in fluid communication with both the sampling port and the sample capturing assemblies. The instrument can further include a sample analysis component in fluid communication with the first valve assembly of the sample inlet component; and an instrument control component in controlling communication with both the sample inlet component and the analysis component. Instrumental analysis methods are provided that can include continuously providing sample to at least one of a plurality of sample capturing assemblies; and selectively analyzing the contents of at least one of the plurality of sample capturing assemblies.

Abstract: A pipette member to be attachable to a container capable of accommodating a tissue and a liquid, is used for isolating cells from the tissue by stirring, and includes: a cylinder member which includes a first opening that is to be accommodated in the container, and a second opening that is to be connected to a cell isolation apparatus, and in which a passage for communicating the first opening with the second opening is defined; and a filter member which is disposed inside the cylinder member, and which separates the passage into a first part that includes the first opening, and a second part that includes the second opening.

Abstract: One embodiment of the invention includes an automated system for collecting analyte. The system comprises a screen supply cartridge for holding a stack of clean tabs including sorbent coated screens (SCS) residing in SCS channels. The stack of tabs are arranged such that SCS tabs directly above and/or below a given SCS tab include SCS channels offset from the SCS channel of the given tab to isolate the SCS channels from one another and the environment. The system includes an air source that provides an analyte to be adsorbed by an SCS channel of a respective tab at a sampling region and a linear actuator that moves a given clean tab into the sampling region for exposing the SCS channel of the given clean tab to the analyte and providing a given exposed tab.

Abstract: Portable devices and related methods for collecting and storing atmospheric samples for subsequent chemical analysis are provided. A sample cartridge according to one implementation includes self-sealing inlet and outlet ports configured to close automatically when not in use, and a sample retention portion between the inlet and outlet ports that is adapted to trap an atmospheric sample. The sample cartridge may also include a memory device for recording data regarding the sample. Another embodiment provides a portable sampler configured to removably secure a self-sealing sample cartridge. A portable sampling device may also be used with an analytical instrument. The analytical instrument may analyze the sample and read the data recorded on the sample cartridge's memory.

Abstract: A sample dispensing apparatus and method for dispensing a sample such as blood and urine collected for inspection from one vessel to another are provided wherein the remaining quantity of a primary sample can be reduced without disturbing the primary sample. When clogging by a separating agent is detected during suction of a sample such as blood and urine collected for inspection, the sample dispensing apparatus performs raising of an aliquot head such that an opening at the free end of a nozzle tip does not come out of the sample liquid surface to dissolve clogging; sucking of the sample under the residual pressure; and additionally sucking of a fixed quantity of the sample to reduce the remaining quantity of the sample.

Abstract: A portable multi-tube air sampler device for capturing samples of trace elements in a suspected contaminated environment which includes a plurality of sample tubes for collecting sample trace elements, parallel inlet and outlet manifolds which minimize the length of the sample inlet path while utilizing short straight sample tubes, a hinged retainer bar mechanism which allows for easy removal and replacement of the various sample tubes, and a removably attachable controller unit which can be installed on the exterior portion of the carrying case for controlling the operation of the sampling protocol. Other embodiments include heated inlet manifold and sample intake paths to prevent contamination accumulation and carryover, a clean cycle option with a filter valved into the inlet flow path to enhance the purging cycle, and a mechanism for converting the present device to a desorbing auto sampler configuration. The present system likewise incorporates a purging cycle prior to each sampling cycle.

Abstract: A method and apparatus for in-situ measurement of soluble contaminant flux rates from sediments in which an inverted desorption chamber containing a sorbent system is filled with water and placed over an area of sediment, whereby the interior of the chamber is isolated from the exterior of the chamber above the sediment. Soluble contaminants released from the sediment are sorbed onto the surface of a sorbent material disposed within a plurality of semipermeable membrane bags disposed within the chamber. Each semipermeable membrane bag is removed from the chamber in a pre-defined sequence over a period of time and the sorbent material in each bag is analyzed to determine an amount of the soluble contaminant sorbed by the sorbent material. From the results of the analyses, the mass of the soluble contaminant removed from the sediment over time can be calculated.

Abstract: A novel multi-gas passive sampler is described, whereby different collection media are packed into one passive sampler to collect a variety of air pollutants (or groups of air pollutants) at the same time. By comparison with known commercially available passive samplers—in which only a single collection medium is used to collect a single air pollutant of or group of air pollutants—the MGPS is more cost effective, convenient to use and more environment-friendly.

Abstract: A filtering system for monitoring fluid emissions from a process includes a plurality of filter assembly sections arranged in a parallel fluid flow manner with respect to each other so as to selectively receive a sample fluid (e.g., a sample gas) entering at an inlet of the system. Each filter assembly section includes a filter unit to filter particulate materials from a fluid flowing through the filter, first and second valves disposed at upstream and downstream locations of the filter unit, and a blowback flow path configured to selectively direct a cleaning fluid through the filter unit in a direction that opposes a direction in which the sample fluid flows through the filter unit. Each filter assembly section can be selectively isolated from other portions of the system so as to prevent the sample fluid from flowing through the filter assembly section while allowing a cleaning fluid to be delivered through the blowback flow path of the filter assembly section.

Abstract: A hybrid valve apparatus for use with an aspiration actuator and a dispensing actuator to transfer fluid from a reservoir to a test site on a substrate surface. The hybrid valve includes a valve assembly movable between an aspiration condition and a dispensing condition, and a manifold device coupled to the valve assembly. The manifold device includes a fluid aspiration conduit having a first aspiration port in fluid communication with the aspiration actuator. On an opposite end of the aspiration conduit is a second aspiration port in selective fluid communication with the valve assembly to selectively aspirate a liquid sample slug from the reservoir into a discrete sample path when the valve assembly is in the aspiration condition. The manifold device further includes a fluid dispensing conduit having a first dispensing port in fluid communication with the dispensing actuator, and a second dispensing port in selective fluid communication with the valve assembly.

Abstract: A monitoring device for use in monitoring the life of a filter used in the operating unit of an air conditioning system. The monitoring device has a support for use in attaching the device to the housing of the operational unit in the air conditioning system, the unit having a least one air conditioning filter holding filter material. At least one tubular arm attached to the support, each arm having an air inlet and an air outlet. The support is mounted in a manner to have a portion of the air passing through the air conditioning unit pass through the arm on the support as well. A sample filter is provided along with mounting means for removably mounting the sample filter on the arm to have air passing through the arm also pass through the sample filter. The sample filter holds the same filter material as the air conditioning filter.

Abstract: A biological specimen filter, for use in a biological specimen collection and transfer system having a vacuum source, comprises a tubular body having an exterior surface, an interior chamber, a first end configured to couple to the vacuum source, and a second end having an opening in communication with the chamber, and a fluid trap extending around at least a portion of a circumference of the exterior surface of the tubular body and sized and shaped to catch fluid flowing along the exterior surface as the tubular body is inverted from a first position, in which the opening is submerged in a fluid source, to a second position, in which the opening is removed from the fluid source.

Abstract: A sampling system for separating gaseous samples from a gas stream containing particulate matter and transporting the gaseous samples to a location outside of the flowing gas stream comprises an inertial filter mounted on the end of a hollow probe, the inertial filter positioned within the flowing gaseous stream. The inertial filter comprises a filter media mounted within a tube such that a portion of the particulate-containing gaseous steam flows through an annular space between the filter media and the tube wall, the gas to be sampled passes through the filter media into an inner space and the filtered gas is then delivered through the hollow probe to analytical devices external to the space containing the flowing gas stream, such as a flue stack.

Abstract: A high throughput microarraying or colony picking robot with an automatic mechanism for exchanging pin heads and an automated washing and drying apparatus. The robot allows a dirty pin head to be deposited on the automated washing and drying apparatus for cleaning without use of the xyz-positioner, while spotting or picking can continue by picking up a clean pin head without having to wait for the dirty pin head to be cleaned. In this way, the speed of operation can be increased without any increase in the acceleration or speed of the x-, y- and z-drives. The dead time normally associated with the washing and drying cycle, which is usually several minutes, is therefore eliminated, and replaced with the much shorter dead time, of only a few tens of seconds, needed for changing between heads.

Abstract: In the distribution apparatus and the method for detaching distribution tips of the present invention, the detaching plate provided with openings being larger in diameter than outer diameter of the nozzle and smaller in diameter than outer diameter of the distribution tip which are disposed in accordance with the arrangement of the nozzles is held to the distributing head with the nozzles set through the openings, and with the stopping portion of the detaching plate stopped by the stop portion of the stop member disposed at the tip detaching stage, the distributing head and the stop member are relatively moved in a direction of vertically moving apart, and thereby, the distribution tips are detached from the bottom ends of the nozzles. In this way, the distribution tip detaching operation can be automatically performed by a simple mechanism.

Abstract: A removable secondary liquid dispensing module for use with an existing, automated liquid handling system that defines a work area having a plurality of discrete work stations. Each of the work stations of the automated liquid handling system includes a lab ware site and alignment structure enabling the removable securing standardized microtiter-plates at respective lab ware site. A plate positioning mechanism is configured to move and position the microtiter plates to and from the lab ware sites of the respective work stations thereof and into engagement with the respective carrier alignment structure thereof. Further, a primary liquid dispensing device is configured for selective contact-type dispensing of discrete quantities of fluid, in the range of about one (1) microliter to about ten (10) milliliters, into the test sites of the microtiter plates secured in the respective alignment structure of the respective work station.

Abstract: A compact, portable, aerosol contaminant extractor having ionization and collection sections through which ambient air may be drawn at a nominal rate so that aerosol particles ionized in the ionization section may be collected on charged plate in the collection section, the charged plate being readily removed for analyses of the particles collected thereon.

Abstract: A method and apparatus are provided for adsorbing surface-active compounds, such as corrosion inhibitors and water, from pressurized gas streams utilizing existing gas pipeline sampling valves. The apparatus includes an adsorption trap assembly containing an adsorption material packing, such as silica gel, fixedly positioned to selectively adsorb any surface-active compound(s)or water in the gas stream passing through the trap. After sampling, the adsorption material packing is removed and treated to desorb any entrained compound(s) for recovery, testing and identification. The method and apparatus have particular utility in determining the presence of corrosion inhibitors that have been added to petroleum pipelines upstream of the sampling point(s).

Abstract: A method that allows an individual to personally test for contaminants in an air supply. The method consists of purchasing the test kit, mounting the test kit to an existing particulate filter, placing the mounted test kit and particulate filter into the filter housing and blowing air through the test kit. The test kit is then removed from the furnace, repackaged and sent to a laboratory for analysis. The air quality test kit comprises a test filter, a filter backing pad, a support and a pair of end caps. The test filter, the filter backing pad and the support form a device to capture and retain particles carried in an airflow.

Abstract: A sampling cartridge for a gas sampling apparatus includes a shell having a cylindrical wall and a sampling window extending through the wall. A pair of spools are coaxially and internally positioned within the shell. The spools are independently rotatable relative to the shell. A first spool may include multiple interval sample collectors while the second spool includes a duration sample collector. Each spool also has a window closing surface which is positioned adjacent the window whenever an access door of the gas sampling apparatus is opened. The sampling cartridge may also include a fully encapsulated section of sample collector material as a negative control, and an integral RF tag for storing chain of custody information including personal identification information of a cartridge replenisher.

Abstract: A sampling cartridge for a gas sampling apparatus includes a shell having a cylindrical wall and a sampling window extending through the wall. A pair of spools are coaxially and internally positioned within the shell. The spools are independently rotatable relative to the shell. A first spool may include multiple interval sample collectors while the second spool includes a duration sample collector. Each spool also has a window closing surface which is positioned adjacent the window whenever an access door of the gas sampling apparatus is opened. The sampling cartridge may also include a fully encapsulated section of sample collector material as a negative control, and an integral RF tag for storing chain of custody information including personal identification information of a cartridge replenisher.

Abstract: A multiple channel pipetting device and pipette shaft, in which each pipette shaft has a circumferential seal receptacle inside, at its upper end in which the circumferential plunger seal is positioned and in which the circumferential plunger seal, at least in the case of a pulled back pipette plunger, definitely remains in the seal receptacle when the pipetted shaft is removed from the shaft carrier.

Abstract: A dosing device is provided and comprises a withdrawal container and a dosing means comprising at least one dosing unit which is a piston-cylinder unit designed as a disposable member. The piston-cylinder unit discharges into a receiving container and valve means is provided to control flow into and out of the piston-cylinder unit.

Abstract: A liquid dispenser characterized by a dispensing head which is movable upward and downward as a whole and comprises a plurality of plungers supported by a plunger plate, drive means for moving the plunger plate upward and downward, a plurality of cylinders in which the plungers slidably fit, and a plurality of nozzles arranged at the lower ends of the cylinders and having configurations adapted to engage airtightly with holes for holding specific dispensing tips, the plurality of nozzles being supported by a single nozzle holder, which is built to be detachable from said dispensing head. According to the invention, only the nozzle holder that support nozzles has to be replaced with another holder conforming to dispensing tips of different dimensions. The arrangement facilitates the replacement and make the dispenser available at lower cost.

Abstract: A pipette for the handling of a syringe. The pipette has jaw chucks which are adjustably arranged with respect to the plunger receptacle, being pivotably mounted on a plunger-gripping device. The syringe is insertable with opened jaw chucks with the plunger head only partially contacting the jaw chucks. The jaw chucks are laterally engageable on the plunger head upon insertion of the syringe. The engaging movement of the jaw chucks on the plunger head is regulated according to the invention so that the engaging movement has a substantially tangential component with respect to the surface of the plunger head. As a result, a desired and form-locking connection to the plunger head of the syringe results that requires a small amount of force.

Abstract: A high air volume to low liquid volume aerosol collector. A high volume flow of aerosol particles is drawn into an annular, centripetal slot in a collector which directs the aerosol flow into a small volume of liquid pool contained is a lower center section of the collector. The annular jet of air impinges into the liquid, imbedding initially airborne particles in the liquid. The liquid in the pool continuously circulates in the lower section of the collector by moving to the center line, then upwardly, and through assistance by a rotating deflector plate passes back into the liquid at the outer area adjacent the impinging air jet which passes upwardly through the liquid pool and through a hollow center of the collector, and is discharged via a side outlet opening. Any liquid droplets escaping with the effluent air are captured by a rotating mist eliminator and moved back toward the liquid pool.

Abstract: A filter device is described for obtaining a filtered sample of fluid for measuring purposes from a container or tube conduit. The device has a closed fluid circuit including a first filter element 4, a pump conduit having a pump 27 therein, and a second filter element 5 arranged so that a sample of fluid is suctioned from the container or tube conduit via the first filter element 4, through the pump conduit 26, 28 and then back to the container or tube via the second filter element 5 or vice versa. An optical probe 17 for measuring purposes can be arranged within the carrier tube 7.

Abstract: Instruments and processes according to the invention provide for the preparation of a fluid sample that has a substantially known concentration of a select particulate matter. In one aspect, the invention is understood as laboratory instruments for sample preparation. These instruments can include a filter that is submersible within a fluid suspension of particulate matter. To collect particulate matter from the fluid suspension, the instruments can cause a fluid flow that pulls fluid across the filter to trap particulate matter against one surface of the filter. The instruments can then remove the filter from the fluid suspension and dispose the filter above a collection vessel such that the side of the filter that is carrying particulate matter is positioned above the opening of the collection vessel.

Abstract: A method and apparatus of sampling a body of water in which discrete samples are successively withdrawn from a body of water and analyte is extracted from the respective samples while integrating the analyte which is extracted from successive samples. A filter unit in which male and female fittings may be locked together, and unlocked to allow replacement of filter membranes/screens discs or elements.