Lock Or Seal For Sampler Insertion Or Removal Patents (Class 73/863.85)
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Patent number: 11767941Abstract: Apparatus for hydrostatic testing of items having a flanged opening, such as flanged pipe sections, which apparatus contains a actuator having a actuator shaft attached to a blind flange, which actuator can be powered from a power source on a remotely operated vehicle, which items include those items located on land as well as subsea. Also provided is a remotely operated vehicle having a power source such as a hydraulic system that is used to operate the actuator on the hydrostatic testing apparatus.Type: GrantFiled: July 21, 2021Date of Patent: September 26, 2023Inventor: Randall M Smith
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Patent number: 11255757Abstract: An apparatus and a method for analysing a solid specimen material by means of ablating particles of the solid specimen material by laser into a carrier liquid, having: a specimen holder for arranging the solid specimen material covered by the carrier liquid, a laser apparatus for irradiating the solid specimen material to produce a suspension of particles of the solid specimen material and the carrier liquid, an analysis apparatus for analysing the particles, an ablation cell with the specimen holder, having a liquid channel for the carrier liquid and having an entry window made of a material that transmits the laser beam, a supply line for supplying the carrier liquid into the liquid channel of the ablation cell and a discharge line for discharging the suspension of particles of the solid specimen material and the carrier liquid from the liquid channel of the ablation cell into the analysis apparatus.Type: GrantFiled: October 5, 2017Date of Patent: February 22, 2022Assignee: TECHNISCHE UNIVERSITÄT WIENInventors: Andreas Limbeck, Maximilian Bonta, Johannes Frank
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Patent number: 11150228Abstract: A detector comprising an analytical apparatus for detecting a substance of interest, and a detector inlet. The detector inlet comprises a flow passage for carrying a flow of fluid, the flow passage comprising a sampling volume, and a sampling inlet adapted to collect samples of the fluid from the sampling volume as the fluid flows past the sampling inlet, and to provide the samples to the analytical apparatus, wherein the how of fluid carries particulates. The detector inlet also comprises a flow director arranged to vary a spatial distribution of the particulates carried by the fluid to increase a relative proportion of the particulates carried past the sampling inlet along the flow passage without entering the sampling volume.Type: GrantFiled: March 2, 2020Date of Patent: October 19, 2021Assignee: Smiths Detection-Watford LimitedInventors: Alastair Clark, Bruce Grant, Matthew Easton, Frederic Fournier
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Patent number: 10571372Abstract: A filtration apparatus and methods of installing, using, and retracting the same. A filtration apparatus includes a compression gland, a ball valve, and a filter pipe. A distal portion of the filter pipe has one or more filtration holes. The filtration apparatus may be installed in a process pipe and the distal portion of the filter pipe may be disposed within the process pipe. The filter pipe can be easily retracted from the process pipe without interruption of the industrial process. The filtration apparatus can be automatically cleaned by compressed air or water.Type: GrantFiled: May 4, 2016Date of Patent: February 25, 2020Assignee: ECOLAB USA INC.Inventors: Darlington Mlambo, David R. Szymborski, David P. Workman, Michael J. Murcia
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Patent number: 10295514Abstract: An assembly and method of using the assembly. The assembly is operable when assembled as a benchtop instrument for sealed penetration of an oxygen sensitive luminescent sensor into sensible communication with an enclosed space of a sealed rigid package to measure oxygen concentration therein, and operable when disassembled as a handheld instrument for sealed penetration of the oxygen sensitive luminescent sensor into sensible communication with an enclosed space of a flexible package to measure oxygen concentration therein. The assembly includes a mechanical punch press equipped with a longitudinally reciprocable fixture equipped with a hollow piercing member, and an oxygen analyzer releasably attachable to the fixture.Type: GrantFiled: October 17, 2016Date of Patent: May 21, 2019Assignee: Mocon, Inc.Inventor: John Eastman
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Patent number: 9983103Abstract: A gas sample extraction assembly for controllably accessing gas in a gas sample container includes a coupler body having a coupler bore and a coupler end for engaging the gas sample container; an upper member having an upper member bore; a biasing member disposed between the upper member and the coupler body; and a stem having a first portion coupled to the upper member bore and a second portion disposed in the coupler bore, the stem being movable relative to the coupler body between a first axial position and a second axial position, wherein the biasing member is configured to bias the stem in the first axial position.Type: GrantFiled: February 25, 2014Date of Patent: May 29, 2018Assignee: Isotech Laboratories, Inc.Inventors: Dennis D. Coleman, Todd M. Coleman
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Patent number: 8978492Abstract: A sampling container having a bottle connected to a cap with the cap in communication with a one-way valve for the transport of fluid into the bottle; and the one-way valve configured to receive fluids there through into the opening of the bottle. Further optional embodiments also include a vacuum adapter for attaching the cap to a vacuum pump.Type: GrantFiled: April 19, 2010Date of Patent: March 17, 2015Assignee: Des-Case CorporationInventors: Jonathan L. Haworth, Cody Curtsinger, Aaron Holmes, Brian Swain
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Patent number: 8974750Abstract: A nozzle device which can perform accurate quantitative suction without being affected by a pressure when, for example, a nozzle (2) is inserted into a closed container (T). The nozzle device has the nozzle (2) that is inserted into the closed container (T) and that sucks a liquid in the closed container (T), an exposure to atmosphere mechanism (3) that opens the closed container (T) to the atmospheric air, and an opening/closing structure (4) that is arranged at a proximal end of the nozzle (2) and that has an internal flow channel (411) communicated with a flow channel in the nozzle (2) and an opening/closing mechanism for opening and closing the internal flow channel (411), and an opening/closing control section (5) that controls the opening/closing mechanism.Type: GrantFiled: December 18, 2008Date of Patent: March 10, 2015Assignee: Horiba, Ltd.Inventors: Soichi Oue, Yoshihiro Yano, Narihiro Oku
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Patent number: 8794825Abstract: A sampling port includes an elongated flexible support tube having an interior surface bounding a first passageway extending between a first end and an opposing second end, the first passageway being closed at the first end of the support tube and open at the second end of the support tube. An elongated flexible sampling tube has an interior surface bounding a second passageway extending between a first end and an opposing second end, the second passageway being open at the first end of the sampling tube, at least a portion of the sampling tube adjacently extending along the length of the support tube and being connected to the support tube. A flange encircles and radially outwardly projecting from the support tube and the sampling tube at a location spaced apart from the first end of the support tube and the first end of the sampling tube.Type: GrantFiled: January 25, 2011Date of Patent: August 5, 2014Assignee: Life Technologies CorporationInventor: Michael E. Goodwin
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Patent number: 8661922Abstract: A sampling tool (100, 200) for use in obtaining a sample of material from within a container comprises a cutter shaft carrying a cutting head (1, 101), the shaft including a passage which has an inlet located at or towards the cutting head (1, 101), a drive mechanism which is adapted to cause the cutter shaft to rotate in a first direction in turn to cause the cutting head to cut a hole in wall of the container and expose the inlet to the material contained within the container, a flexible seal (3, 103) carried by the cutter shaft which is located so that with the inlet in contact with the fluid the seal extends at least partially through the hole, a clamp mechanism which is operable once the seal is located in the hole such that continued rotation of the cutter shaft pulls the cutting head (1, 101) back towards the hole to mechanically clamp the seal (3, 103) around the hole; and a self sealing connector which is in connection with an outlet of the passage and through which a sample may be withdrawn into a sType: GrantFiled: September 16, 2009Date of Patent: March 4, 2014Assignee: MMIC EOD LimitedInventor: Nick Sales
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Publication number: 20140053662Abstract: A cap having a core structure dimensioned to receive a pipette therethrough. The cap includes two axially aligned frangible seals that are affixed to the core structure in a spaced-apart relationship. The frangible seals include a foil layer and are constructed so that air passageways are formed between the frangible seals and a pipette tip when the pipette tip penetrates the frangible seals. The cap optionally includes a filter interposed between the first and second frangible seals.Type: ApplicationFiled: November 15, 2011Publication date: February 27, 2014Applicant: GEN-PROBE INCORPORATEDInventors: Daniel L. Kacian, Mark R. Kennedy, Nick M. Carter
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Patent number: 8621944Abstract: A device, system, and method for passively sealing a vessel containing a fluid and for sampling the fluid without carry-over or cross-contamination between the fluid sampling device, the sealing septum, and the vessel contents. The device includes an actuated septum having a plurality of septum fingers, to passively seal the vessel, and an actuation device, to open the passive seal without carry-over or cross-contamination. Each of the plurality of septum fingers includes a corresponding rib portion. The actuation device can be an actuation ring having an annulus. The plurality of septum fingers and corresponding rib portions are disposed internal or substantially internal to the vessel, while the actuation device is disposed external to the vessel.Type: GrantFiled: April 14, 2008Date of Patent: January 7, 2014Assignee: Siemens Healthcare Diagnostics Inc.Inventor: David Stein
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Patent number: 8539846Abstract: Sample or specimen retrieval may be performed via a tool that includes a multi-section tool bit which carries a plug. A cutter of the tool bit forms (e.g., drill, mill, bore, ream) a hole in a structure. A mandrel on a leading section of the tool bit sealing engages the plug in the hole from a blindside of the structure. A sample chamber of a trailing section of the tool bit extends into the hole through a passage in the plug and is opened. Optionally an auger portion of the trailing section rotates to acquire the sample in the sample chamber. The sample chamber is closed and withdrawn from hole and the mandrel seats in the passage to seal the plug. The trailing section is separated from the leading section, and retrieved along with the sample. Such may be particularly suitable for use with submersible ROVs.Type: GrantFiled: October 17, 2011Date of Patent: September 24, 2013Assignee: Global Diving & Salvage, Inc.Inventor: Eric Crumpton
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Publication number: 20130160574Abstract: A cap having a core structure dimensioned to receive a pipette therethrough. The cap includes two axially aligned frangible seals that are affixed to the core structure in a spaced-apart relationship. The frangible seals include a foil layer and are constructed so that air passageways are formed between the frangible seals and a pipette tip when the pipette tip penetrates the frangible seals. The cap optionally includes a filter interposed between the first and second frangible seals.Type: ApplicationFiled: November 15, 2011Publication date: June 27, 2013Applicant: GEN-PROBE INCORPORATEDInventors: Daniel L. Kacian, Mark R. Kennedy, Nick M. Carter
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Patent number: 8444912Abstract: A heat treatment furnace that allows the atmosphere in the heat treatment furnace to be controlled with favorable accuracy includes a second heating zone identified as a reaction chamber, having a floor belt to hold a workpiece, and an atmosphere collect pipe having an opening in the second heating zone to collect an atmosphere in the second heating zone through the opening. The atmosphere collect pipe is installed to allow the distance between the opening and the floor belt to be modified.Type: GrantFiled: June 19, 2008Date of Patent: May 21, 2013Assignee: NTN CorporationInventor: Chikara Ohki
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Patent number: 8408078Abstract: The invention discloses an apparatus for removing samples or introducing fluids from/into system(s) having flexible walls. A sampler/fluid dispenser (3) is fixed on the outside with a connecting area (4) of its base (5) on a sample removal region/fluid dispensing region (6) of the flexible wall (2) and, in its interior, has a severing element (8). At least the severing element (8) can be pushed forward in the direction of the sample removal region/fluid dispensing region (6) in order to remove the samples and in order to introduce fluids, in such a way that the wall (2) can be perforated within the sample removal region/fluid dispensing region (6). The system (1) comprises containers, bags or tubes for filling, mixing, transporting, storage of media, such as biological liquids, sera, buffers, ultra-pure water and can be used as biological reactors or cell culture vessels in the pharmaceutical and biotechnical industry.Type: GrantFiled: March 5, 2007Date of Patent: April 2, 2013Assignee: Sartorius Stedim Biotech GmbHInventors: Heyo Mennenga, Oscar-Werner Reif, Dieter Schmidt, Reinhard Vogt
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Patent number: 8322232Abstract: An on-stream sample collection and conditioning system, which is easier to construct, implement, maintain, and is more cost efficient then existing systems. The preferred embodiment of the present invention contemplates a modular system adaptable to a variety of diverse sample conditioning requirements. The system provides a docking surface specifically designed to receive modular conditioning or sampling components or the like in order to readily engage a system of passages to provide fluid flow between the mounted components. An embodiment of the invention provides a flow component having grooves formed therethrough reflecting the desired flow configuration, which is isolated from the flow component and sealed and to provide flow passages. The docking surface has access apertures formed to engage the flow passages, providing access to modular components mounted thereon.Type: GrantFiled: December 22, 2009Date of Patent: December 4, 2012Assignee: A+ Manufacturing, LLCInventor: Donald P Mayeaux
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Patent number: 8196480Abstract: An on-stream sample collection and conditioning system, which is easier to construct, implement, maintain, and is more cost efficient then existing systems. The preferred embodiment of the present invention contemplates a modular system adaptable to a variety of diverse sample conditioning requirements. The system provides a docking surface specifically designed to receive modular conditioning or sampling components or the like in order to readily engage a system of passages to provide fluid flow between the mounted components.Type: GrantFiled: November 5, 2008Date of Patent: June 12, 2012Assignee: A+ Manufacturing, LLCInventor: Donald P. Mayeaux
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Publication number: 20120132014Abstract: A sampling container for receiving media from a container filling system includes a closed base region, a peripheral wall adjoining the base region and extending substantially orthogonal to the base region, and a filling region opposite the base region and adjoining the peripheral wall. The filling region has a container neck extending substantially orthogonal to the base region and includes a filling opening. An outer thread is arranged over an outer periphery of the container neck. The thread has an outer diameter between 44 and 46 mm and a core diameter between 41 and 43 mm, and rounded edges, at least over portions, with a radius between 0.95 and 1.05 mm. The container neck can be arranged in a receiver of a sampling head, during the sampling process so that the container is sealed in a media-tight manner in relation to an ambient environment.Type: ApplicationFiled: November 28, 2011Publication date: May 31, 2012Inventors: Stephan Hartmann, Martin Doebler
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Publication number: 20120118082Abstract: A soil-cement sampling device and method of sampling soil-cement is provided. The soil-cement sampling device may include an inner tube arranged within an outer tube. The inner tube may be removably connected to the outer tube and may be split into two longitudinal sections removably connected to each other. The inner and outer tubes may be inserted into a recently mixed soil-cement mixture before it hardens and a sample of the soil-cement mixture may be collected in the inner tube after it hardens. Once the sample hardens, the inner tube may be removed from the outer tube and the longitudinal sections may be separated to expose the soil-cement sample for inspection and testing.Type: ApplicationFiled: November 11, 2010Publication date: May 17, 2012Applicant: SCHNABEL FOUNDATION COMPANYInventors: Keith Schnupp, Allen Stanton
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Patent number: 8171807Abstract: An iso-kinetic probe for the analysis of the pollution of the gases generated by an aircraft engine is disclosed. The probe includes an air tapping tube having an upstream end inserted into a conduit wherein a gas stream flows and a gas stream inlet velocity adjustment device provided at an orifice of the tapping tube. The tube has a downstream end mounted in a fixed manner on a base. The base has an outer diameter mounted in an inner diameter d of a passage bushing. The inner diameter d of the passage bushing being sufficiently great so that the upstream end of the tube is suitable to fit through the inner diameter of the passage bushing. The probe also includes a measurement chamber having an end connected to the base.Type: GrantFiled: October 22, 2008Date of Patent: May 8, 2012Assignee: SNECMAInventors: Sebastien Carichon, Serge Del Arco, Nadine Alice Helene Harivel
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Patent number: 8122778Abstract: In accordance with one embodiment of the present invention, a probe assembly comprising a flange assembly, a probe platform, a platform extension, an extension enclosure, and a fluid coupling assembly is provided. The fluid coupling assembly comprises a removable portion and a retained portion. An engaging interface of the retained portion cooperates with an engaging interface of the removable portion such that, with engagement of the removable and retained portions, respective fluid passages of the removable and retained portions form one or more integrated fluid channels configured to permit passage of fluid through the fluid coupling assembly. The probe assembly is configured such that the probe platform, the platform extension, and the removable portion of the fluid coupling assembly are interconnected and are configured to be withdrawn simultaneously from the probe assembly independent of the retained portion of the fluid coupling assembly.Type: GrantFiled: July 3, 2008Date of Patent: February 28, 2012Assignee: Perma Pure LLCInventors: David J. Burke, T. Paul Smith, Robert T. MacRae
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Patent number: 8104331Abstract: Applicants' teachings relate to a method and device to extract components contained in a fluid. More particularly, the applicants' teachings are directed towards a method and sampling device for quick extraction of targeted components from their in vivo surroundings. In accordance with various embodiments of applicants' teachings a sampling device and method to extract components, such as, for example, analytes, from a fluid is provided. The device is interfaced with a fluid source, such as, for example, but not limited to, a circulatory system of an animal, to enable extraction of target molecules with minimal loss of fluid (e.g., blood) to the source. The device facilitates an interface between the circulatory system of an animal and a suitable sampling probe such as, for example, a solid phase microextraction (SPME) probe. The targeted compounds are desorbed in small volumes of solvents that can be analyzed with highly specific instruments.Type: GrantFiled: July 19, 2007Date of Patent: January 31, 2012Assignees: Noab Biodiscoveries Inc.Inventors: Janusz Pawliszyn, Marcel Musteata, Ines Ana Maria De Lannoy, Kenneth Bradley Gien
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Patent number: 8008065Abstract: A port for use with a bioreactor vessel comprising: i) a base member comprising a hollow tubular portion and a base plate configured to be sealingly affixed to a hole in the wall of a bioreactor vessel ii) a hollow, generally tubular bushing member for containing electrical, optical, microfluidic and/or chemical monitoring components which bushing member fits inside the bore of the tubular portion of the base member, both the base member and bushing member providing access to the contents of a bioreactor by; iii) a monitoring assembly inserted into the bushing member which assembly comprises means for providing incoming optical and/or electrical signals and means for collecting and transmitting measurement signals resulting from the interaction of incoming optical and/or electrical signals with the contents of a bioreactor; and iv) a cover which maintains the position and alignment of components ii) and iii) relative to the base member.Type: GrantFiled: March 26, 2007Date of Patent: August 30, 2011Assignee: Finesse Solutions, LLC.Inventors: Mark Selker, Timothy Johnston, Barbara Paldus
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Patent number: 7955843Abstract: An apparatus and method for an aseptic fluidic interface between bioprocess systems is provided. The apparatus includes an inlet valve, adapted for automatic control, that is coupled to a biofluid source site. A sampling conduit extends from the inlet valve to an outlet valve. The outlet valve is adapted for automatic control and is coupled to a biofluid process site. A trap is at the sampling conduit. A waste valve, adapted for automatic control, is located at a waste conduit extending from the sampling conduit to a waste site. Also included is a wash fluid source that is coupled to at least one of the inlet or outlet valves. In the method, the sample is automatically directed to the biofluid process site by opening the outlet valve, and closing the waste valve. Also included is isolating the biofluid sites by closing the inlet and outlet valves, and opening the waste valve to drain biofluid from the trap to the waste site.Type: GrantFiled: November 27, 2006Date of Patent: June 7, 2011Assignee: Groton Biosystems, LLCInventor: George E. Barringer, Jr.
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Patent number: 7930947Abstract: An apparatus and method for piercing a drum plug of a drum in order to sample and/or vent gases that may accumulate in a space of the drum is provided. The drum is not damaged and can be reused since the pierced drum plug can be subsequently replaced. The apparatus includes a frame that is configured for engagement with the drum. A cylinder actuated by a fluid is mounted to the frame. A piercer is placed into communication with the cylinder so that actuation of the cylinder causes the piercer to move in a linear direction so that the piercer may puncture the drum plug of the drum.Type: GrantFiled: December 7, 2005Date of Patent: April 26, 2011Assignee: Savannah River Nuclear Solutions, LLCInventor: Kevin T. Counts
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Patent number: 7802485Abstract: Arrangements for withdrawing carefully controlled samples from an active flue gas source are disclosed. A testing assembly is provided for connection to downstream processing equipment to obtain a sample from a gas stream. Included is a probe, a flexible sample line and a coupler joining the probe and the flexible sample line. At least one externally controlled or self-regulating heating cable is put in heating communication with the flexible line. A receptacle engaging the coupler is also provided for positioning the probe with respect to the flue gas source.Type: GrantFiled: September 28, 2007Date of Patent: September 28, 2010Assignee: Clean Air Engineering, Inc.Inventors: James E. Wright, Daniel J. Rybarski, Volker Schmid
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Publication number: 20100116069Abstract: Container seal having an integrated safety arrangement for a sample carrier, wherein the container seal (3) is in the form of a screw- or turning-closure, a lid, a cap, a plug or the like and the sample carrier is a swab having a sample collector (1) in form of a piece of cotton wool (1) or another suitable collector attached to a swab shaft (2), characterized in that the container seal (3) is provided with means for arresting the swab shaft (2) in guiding tube (4), wherein these arresting means allow a single insertion of the swab shaft (2) into the guiding tube (4) and prevent a movement into the opposite direction.Type: ApplicationFiled: November 12, 2009Publication date: May 13, 2010Applicant: EPPENDORF AGInventor: Dieter Schmiedl
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Publication number: 20100107784Abstract: A device, system, and method for passively sealing a vessel containing a fluid and for sampling the fluid without carry-over or cross-contamination between the fluid sampling device, the sealing septum, and the vessel contents. The device includes an actuated septum having a plurality of septum fingers, to passively seal the vessel, and an actuation device, to open the passive seal without carry-over or cross-contamination. Each of the plurality of septum fingers includes a corresponding rib portion. The actuation device can be an actuation ring having an annulus. The plurality of septum fingers and corresponding rib portions are disposed internal or substantially internal to the vessel, while the actuation device is disposed external to the vessel.Type: ApplicationFiled: April 14, 2008Publication date: May 6, 2010Applicant: Siemens Healthcare Diagnostics Inc.Inventor: David Stein
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Patent number: 7662110Abstract: Novel devices which can be used to both collect blood samples from and administer medical fluids to a patient on a repeated and continual basis using one rather than multiple needle insertions. The device typically includes a main tubing segment confluently connected to a cannula for insertion in the patient's vein. A syringe port and a volumeter for collecting blood branch separately from the main tubing segment. The device is used to collect blood by attaching an empty blood collection syringe to the syringe port, inserting the cannula in the patient's vein, allowing passive flow of blood from the main tubing segment into the volumeter under intrinsic venous blood pressure and capillary action, and then facilitating active flow of blood from the volumeter into the blood collection syringe by extending the syringe plunger. The device may be used to administer medical fluids to the patient through the main tubing segment from a medical fluid syringe or catheter attached to the syringe port.Type: GrantFiled: July 30, 2003Date of Patent: February 16, 2010Assignee: One Stick, LLCInventor: Patrice Flaherty
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Publication number: 20090178496Abstract: A reagent vessel cap includes a sealing member for sealing the opening of a vessel body; an pressurizing member linked to a retaining part for sealing the sealing member, for bringing the sealing member in close contact with the opening all the time, wherein when pressure is applied, the pressurizing member lifts the sealing member against the biasing force of itself to open the vessel and, when the pressure is eliminated, the pressurizing member returns to position by the biasing force to close the vessel by the sealing member; and a cap body capable of mounting the sealing member and the pressurizing member to the opening of the vessel body containing a reagent. The reagent is collected using the cap structure.Type: ApplicationFiled: January 13, 2009Publication date: July 16, 2009Applicant: FUJIREBIO INC.Inventors: Hiroyuki TAKAHASHI, Eiichiro TANAKA, Hiroyuki NAKAMURA
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Patent number: 7500581Abstract: A liquid transfer tool is provided that facilitates safe removal or transfer of liquids from containers in the upright position. The tool includes a retractable sealed tube that can pierce a seal and that extends to the bottom of the container to extract substantially all of the liquid disposed in the container.Type: GrantFiled: May 25, 2005Date of Patent: March 10, 2009Assignee: International Business Machines CorporationInventors: Neil O'Leary, Frederick Tedesco
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Patent number: 7481978Abstract: Apparatus for aspirating liquid from a container, e.g., a test tube, having a puncturable stopper includes a pair of stepper motors that share a common linear actuator or drive member. One motor operates to axially advance the linear drive member (preferably a lead screw) to a position in which it serves to position a rigidly connected tube-detector/stripper member in engagement with the top of a stopper on a tube. Thereafter, the second motor operates to move along the surface of the same drive member to advance an aspiration probe through the engaged stopper and into a liquid aspirating position within the tube. Preferably, a linear guide rail, slidably-mounted on a frame that supports the liquid-aspirating apparatus, serves to guide both the movement of the aspiration probe and the linear drive member. As a result of the shared components, the apparatus is highly precise and reliable.Type: GrantFiled: March 23, 2005Date of Patent: January 27, 2009Assignee: Beckman Coulter, Inc.Inventors: William Weigong Li, Craig R. Veiner, Sergio Cabrera
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Publication number: 20090019954Abstract: Connector which provide conduits between a sealed environment and an exterior of the environment includes a housing, a plurality of internal conduits extending from a first side of the housing, each adapted to communicate with a respective sampling device situated in the sealed environment, and a single external conduit extending from a second side of the housing opposite the first side and adapted to communicate with a measurement device exterior of the sealed environment. The housing is constructed to enable each internal conduits to alternatingly align with the external conduit such that each sampling device is able to communicate with the measurement device. By providing a connector which is able to provide a flow passage between multiple sampling devices and a single measurement device, at different times, it is not necessary to enter the sealed environment in order to configure a single sampling device in communication with the measurement device.Type: ApplicationFiled: July 19, 2007Publication date: January 22, 2009Applicant: Enzon Pharmaceuticals, Inc.Inventor: Roy L. Evans
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Patent number: 7464614Abstract: An offline solid phase microextraction (SPME) sampling apparatus for enabling SPME samples to be taken a number of times from a previously collected fluid sample (e.g. sample atmosphere) stored in a fused silica lined bottle which keeps volatile organics in the fluid sample stable for weeks at a time. The offline SPME sampling apparatus has a hollow body surrounding a sampling chamber, with multiple ports through which a portion of a previously collected fluid sample may be (a) released into the sampling chamber, (b) SPME sampled to collect analytes for subsequent GC analysis, and (c) flushed/purged using a fluidically connected vacuum source and purging fluid source to prepare the sampling chamber for additional SPME samplings of the same original fluid sample, such as may have been collected in situ from a headspace.Type: GrantFiled: May 18, 2006Date of Patent: December 16, 2008Assignee: Lawrence Livermore National Security, LLCInventor: Chris A. Harvey
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Publication number: 20080245163Abstract: A cap having a plurality of rib structures situated on an inner wall of the cap to facilitate the formation of air passageways as the cap is penetrated by a pipette tip. The air passageways aid in venting air from a fluid-holding vessel closed with the cap.Type: ApplicationFiled: June 17, 2008Publication date: October 9, 2008Applicant: GEN-PROBE INCORPORATEDInventors: Mordi I. IHEME, Daniel L. KACIAN, Mark R. KENNEDY
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Patent number: 7427379Abstract: A liquid dispensing apparatus comprises a liquid reservoir (32), an outlet port (6; 36) and driving means for forcing liquid (4) through the outlet port (6, 36). The driving means generates a pulse of gas which impinges upon the liquid (4) in the reservoir (32) so as to force liquid (4) through the outlet port (6, 36). Also disclosed is a cassette comprising a plurality of cartridges for dispensing liquid therefrom. Each cartridge comprises a liquid reservoir (32) and an outlet member (36) mounted so as to close an opening (34) in the liquid reservoir (32). The outlet member (36) provides an outlet port through which the liquid can be forced by a pulse of pressurised gas.Type: GrantFiled: March 20, 2000Date of Patent: September 23, 2008Assignee: Biotage ABInventors: Peter Hagerlid, Hanno Ehring, Björn Ekström
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Patent number: 7374054Abstract: A vial closure device, a sample vial incorporating such a vial closure device, and certain methods of using such a vial and closure device. The vial and closure device are intended to contain a gaseous sample or a headspace gas present above a liquid or solid material, so that the gaseous sample or headspace gas can be conveniently analyzed, typically by means of an autosampler connected to an analytical instrument such as a mass spectrometer. Mass spectrometric methods of determining the isotopic concentration of hydrogen and oxygen comprised in aqueous samples contained in vials fitted with such closure devices are disclosed. The vial closure device comprises a hollow body member locatable in the mouth of a vial, and a first seal for making a substantially gas-tight seal between the exterior of said hollow body member and said vial.Type: GrantFiled: December 4, 2003Date of Patent: May 20, 2008Assignee: Micromass UK LimitedInventor: Timothy Graham Brockwell
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Publication number: 20070227270Abstract: The invention discloses an apparatus for removing samples or introducing fluids from/into system(s) having flexible walls. A sampler/fluid dispenser (3) is fixed on the outside with a connecting area (4) of its base (5) on a sample removal region/fluid dispensing region (6) of the flexible wall (2) and, in its interior, has a severing element (8). At least the severing element (8) can be pushed forward in the direction of the sample removal region/fluid dispensing region (6) in order to remove the samples and in order to introduce fluids, in such a way that the wall (2) can be perforated within the sample removal region/fluid dispensing region (6). The system (1) comprises containers, bags or tubes for filling, mixing, transporting, storage of media, such as biological liquids, sera, buffers, ultra-pure water and can be used as biological reactors or cell culture vessels in the pharmaceutical and biotechnical industry.Type: ApplicationFiled: March 5, 2007Publication date: October 4, 2007Applicant: Sartorius AGInventors: Heyo Mennenga, Oscar-Werner Reif, Dieter Schmidt, Reinhard Vogt
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Patent number: 7272980Abstract: A method of using an aseptic sampling arrangement. The sampling arrangement includes a septum cartridge and a securing element for use with a fluid enclosure. A locking arrangement is provided to allow selective access to the septum cartridge and the securing element. The sampling arrangement further includes a needle, a tube, and a collection bag. The sampling arrangement can be used to monitor the quality of a fluid product. The method of monitoring includes obtaining a fluid product sample from the fluid enclosure within the collection bag. The collection bag is then incubated for a period of time during which oxygen permeates the bag to simulate post-pasteurizing conditions and/or pre-pasteurizing conditions of the fluid product. The method further includes monitoring the level of contamination detected within the fluid product sample.Type: GrantFiled: June 20, 2005Date of Patent: September 25, 2007Inventor: Darrell Lee Bigalke
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Patent number: 7272981Abstract: An aseptic sampling arrangement that provides selective access to an interior of a fluid enclosure. The sampling arrangement includes a septum cartridge and a securing element for use with the fluid enclosure. A locking arrangement is provided to allow selective access to the septum cartridge and the securing element. The locking arrangement includes a base, a cover, and a locking device that secures the cover in relation to the base.Type: GrantFiled: November 29, 2006Date of Patent: September 25, 2007Inventor: Darrell Lee Bigalke
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Patent number: 7155989Abstract: A test port assembly and method are utilized for returning air characteristics within a closed chamber. The test port assembly is positioned in an exterior wall or panel and as required the test port is opened by removing a threaded cap. A thermometer can then be inserted through the test port assembly and the temperature of the air within the chamber quickly determined.Type: GrantFiled: August 11, 2004Date of Patent: January 2, 2007Assignee: Environmental Air Systems, Inc.Inventors: Stewart J. Gerold, Ronald W. Gardner
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Patent number: 7082849Abstract: A method and apparatus for ensuring the collecting volatile constituents contained in a solid sample S such as leaf tobacco. In particular, a sample vessel 10 for containing a sample of a solid containing volatile constituents, a gas feeding device 16 for filling the sample vessel with inert gas, a thermostatic chamber 12 for containing the sample vessel and keeping the sample contained in the sample vessel at a predetermined temperature, and a canister 20 designed to be depressurized in advance and selectively connected to the sample vessel are provided. The sample vessel containing the sample S is filled with inert gas, and the sample S is kept at a predetermined temperature. Thereafter, the depressurized canister is connected to the sample vessel, and the constituents evaporating and/or escaping from the sample are collected.Type: GrantFiled: July 24, 2003Date of Patent: August 1, 2006Assignee: Japan Tobacco Inc.Inventors: Masahiro Chida, Yukio Sone, Taro Yonezawa
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Patent number: 7082848Abstract: An injection needle particularly intended for transferring a representative fluid sample into a sample bottle (1) is closed by a membrane (2) made from a rubber elastic material. The needle has a tubular inner wall (6) having a needle point (8), and a tubular outer wall (10) concentrically surrounding and radially spaced from the inner wall (6) at least along a portion thereof distant from the needle point (8) and, at its end facing the needle point, having a conically tapering portion (12) sealingly engaging the inner wall (6). The outer wall (10) is provided with at least two apertures (14, 16) spaced longitudinally of the needle.Type: GrantFiled: March 16, 2005Date of Patent: August 1, 2006Inventor: Sølve Fjerdingstad
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Patent number: 7044010Abstract: An aseptic, continuous sampling arrangement used in a fluid transportation system, the arrangement including an elbow pipe and a septum cartridge. The sampling arrangement further including a needle, a tube, and a collection reservoir, arranged such that the collection reservoir is in fluid contact with the fluid transportation system. The sampling arrangement configured to create a non-laminar fluid flow region from which a continuous sample of fluid material is drawn.Type: GrantFiled: November 19, 2004Date of Patent: May 16, 2006Inventor: Darrell Lee Bigalke
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Patent number: 6886420Abstract: An apparatus for extracting samples of product such as liquid or gas from a product chamber. The apparatus comprises a sample chamber arranged in a housing for movement between positions projected into and retracted from the product chamber. The housing is connected to a lateral side of the product chamber in such a manner as to surround an opening thereof in a sealing relation. The apparatus further has a product outlet and a plunger that includes the sample chamber and is supported for axial movement in the housing which is configured as a cylinder.Type: GrantFiled: February 1, 2002Date of Patent: May 3, 2005Assignee: RHE Haendel Engineering GmbH & Co KGInventor: Elmar Händel
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Patent number: 6869800Abstract: An instrument comprising a housing (30) having a fluid-tight seal and a probe (10), adapted to carry a catalyst or sorbent (37), for monitoring a process fluid stream or the behavior of a catalyst or sorbent placed therein. The use of such an instrument permits investigation of catalyst or sorbent behavior in process fluid streams without the need for process shut down or construction of separate process equipment.Type: GrantFiled: January 10, 2002Date of Patent: March 22, 2005Assignee: Imperial Chemical Industries PLCInventors: Robert D Torgerson, Peter E J Abbott
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Patent number: 6860162Abstract: A sampler for obtaining wine samples from a wine holding tank is characterized by a manually operable sampler and a connecting device for coupling the sampler to an opening to the tank. The connecting device has open and closed states and the sampler is coupled to the connecting device while it is closed, after which the connecting device is opened to establish a path between the sampler and tank opening. A probe of the sampler, having a forward sample receiving inlet that may be opened and closed, is then manually extended, while its inlet is closed, through the connecting device and tank opening into and through lees deposited as a sediment layer in the region of the tank opening, until the probe inlet is positioned beyond the sediment layer and in wine that is relatively free of sediment. The probe inlet is then opened for flow of a sample of wine from the tank into the inlet and through and out of the probe to a collection container.Type: GrantFiled: February 6, 2004Date of Patent: March 1, 2005Inventor: Ben E. Jaeger
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Patent number: 6854345Abstract: An assembly adapted to be affixed to a container which contains a sample fluid, and a method of affixing the assembly to the container, are provided. In particular, a contact pressure can be applied to a surface of the container, such that a particular arrangement, which has a portion situated within an opening of the container, is affixed to the container without piercing the surface of the container. For example, the container can be a tank, the particular arrangement can be a sensor arrangement, and a further arrangement can be used to affix the particular arrangement to the container. Moreover, the contact pressure preferably can be applied to an exterior surface of the container so that the further arrangement may be more accessible to a user of the assembly.Type: GrantFiled: September 23, 2002Date of Patent: February 15, 2005Assignee: SMAR Research CorporationInventors: Evaristo Orellana Alves, Clóvis Catananti Júnior
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Patent number: 6845676Abstract: An aseptic, continuous sampling arrangement used in a fluid transportation system, the arrangement including an elbow pipe and a septum cartridge. The sampling arrangement further including a needle, a tube, and a collection reservoir, arranged such that the collection reservoir is in fluid contact with the fluid transportation system. The sampling arrangement configured to create a non-laminar fluid flow region from which a continuous sample of fluid material is drawn.Type: GrantFiled: December 14, 2001Date of Patent: January 25, 2005Inventor: Darrell Lee Bigalke