Sample Holder Patents (Class 73/864.91)
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Patent number: 12055465Abstract: A low-pressure cryogenic fluid sampling system includes a cryogenic sample handle assembly; a transfer and vaporization tubular loop; and a sample vessel. The sample handle assembly connects to a cryogenic storage vessel containing a cryogenic fluid. The tubular loop connects to the cryogenic sample handle assembly. The sample vessel removably connects to the transfer and vaporization tubular loop and accommodates a gaseous sample having a pressure lower than about 200 kPa. A method of collecting a gaseous sample with the sampling system includes purging the sample vessel; actuating the handle to purge and refrigerate the tubular loop; extracting a volume of a cryogenic fluid from the storage vessel into the loop to vaporize the cryogenic fluid and produce a gaseous sample; and transferring the sample from the tubular loop into the sample vessel. The sampling system is safer, maintains stoichiometric quantities in the cryogenic liquid, and reduces cross contamination.Type: GrantFiled: December 29, 2021Date of Patent: August 6, 2024Inventor: Siegfried Georg Mueller
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Patent number: 11879863Abstract: The present invention provides a method for analyzing a liquid sample that solves a problem of a kinetically slow equilibrium at a liquid-solid interface, the problem occurring when liquid sample analysis is performed with a chemical sensor. In the method for analyzing a liquid sample according to an embodiment of the present invention, a component to be analyzed in a liquid sample is adsorbed on a receptor layer of a chemical sensor, one or more kinds of gases are then supplied to the chemical sensor, and a response thereof is measured. As a result, since a slow equilibrium at a liquid-solid interface is not used, a high-sensitivity measurement can be performed in a short time, and existing findings regarding analysis of gas samples on which much progress in research has been achieved can be used.Type: GrantFiled: November 13, 2019Date of Patent: January 23, 2024Assignee: NATIONAL INSTITUTE FOR MATERIALS SCIENCEInventors: Kosuke Minami, Genki Yoshikawa
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Patent number: 11857977Abstract: A fixing clamp for a microfluidic chip includes a set of sub-clamps arranged to be spaced apart on left and right. Each of the sub-clamps includes an upper plate body with a first passage, the first passage having a first outer interface and a first chip docking port, and the first chip docking port being located on a lower surface of the upper plate body and at one end of the upper plate body facing the other sub-clamp; a lower plate body with a second passage, the second passage having a second outer interface and a second chip docking port, and the second chip docking port being located on an upper surface of the lower plate body and at one end of the lower plate body facing the other sub-clamp; and a spacing adjusting mechanism connecting the upper plate body and the lower plate body together.Type: GrantFiled: August 26, 2020Date of Patent: January 2, 2024Assignee: Tsinghua UniversityInventors: Moran Wang, Wenhai Lei
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Patent number: 11846149Abstract: A core sampling and preservation system comprises the following sequentially connected modules: a drive module (300), a preservation module (200) and a core sampling module (100). The core sampling module (100) comprises a core drilling tool and a core sample storage compartment. The preservation module (200) comprises a core sample preservation container. The drive module comprises a core drill having a liquid channel. The core sample preservation container comprises an inner core barrel (28), an outer core barrel (26) and an energy storage device (229). The outer core barrel (26) is sleeved onto the inner core barrel (28). An upper end of the inner core barrel (28) is in communication with a liquid nitrogen storage tank (225). The liquid nitrogen storage tank (225) is positioned inside the outer core barrel (26). The energy storage device (229) is in communication with the outer core barrel (26). The outer core barrel (26) is provided with a butterfly valve (23).Type: GrantFiled: March 15, 2019Date of Patent: December 19, 2023Assignee: SHENZHEN UNIVERSITYInventors: Heping Xie, Mingzhong Gao, Ling Chen, Cunbao Li, Jianbo Zhu, Jun Guo, Zhiyi Liao, Cong Li, Zhiqiang He
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Patent number: 11840890Abstract: A system for the in-situ retained coring of a rock sample has a driving module (300), a retaining module (200), and a coring module (100) which are connected in sequence. The coring module (100) includes a rock core drilling tool and a rock core sample storage cylinder, the retaining module (200) includes a rock core sample retaining compartment. The driving module includes a coring drill machine that has a drill machine outer cylinder unlocking mechanism. The rock core drilling tool includes a coring drill tool, a core catcher (11), and an inner core pipe (12). The coring drill tool has an outer core pipe (13) and a hollow drill bit (14). The rock core sample retaining compartment has an inner coring cylinder (28), an outer coring cylinder (26), and an energy accumulator (229).Type: GrantFiled: March 15, 2019Date of Patent: December 12, 2023Assignee: SHENZHEN UNIVERSITYInventors: Heping Xie, Mingzhong Gao, Ling Chen, Cunbao Li, Jianbo Zhu, Zhiyi Liao, Cong Li, Jun Guo, Zhiqiang He
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Patent number: 11814646Abstract: An insect culture maintenance system includes a sequence of open-ended cylindrical tubes [500, 502, 504, 506] joined pairwise alternately at their tops and bottoms using multiple dual-cap connectors. Each dual-capped connector has a channel from an inside of a first cap to an inside of a second cap. In use, connectors that cap the bottoms of the tubes [508, 512] are filled with insect food media [518, 520], while connectors that cap the tops of the tubes [510] are open. As a result of this design, adults pass from one tube to the next through the top dual-cap connectors, while larvae pass from one tube to the next through the bottom dual-cap connectors, resulting in propagation of subsequent generations of insects through the sequence of tubes.Type: GrantFiled: January 26, 2022Date of Patent: November 14, 2023Assignee: The Regents of the University of CaliforniaInventor: William T. Sullivan
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Patent number: 11788371Abstract: A coring device has core drilling tool, a core catcher, a rock core barrel, a drilling machine outer cylinder, a flap valve and an inner rod for pulling the rock core barrel. The core catcher is provided inside the lower end of the rock core barrel. The core drilling tool includes an outer core tube and a hollow drill bit. The upper end of the outer core tube is connected to the lower end of the drilling machine outer cylinder. The lower end of the outer core tube is connected to the drill bit. The lower end of the inner rod protrudes into the rock core barrel and is movable axially by a certain distance relative to the rock core barrel. The flap valve includes a valve seat and a sealing flap. The valve seat is coaxially mounted on the inner wall of the drilling machine outer cylinder.Type: GrantFiled: November 12, 2018Date of Patent: October 17, 2023Assignee: SHENZHEN UNIVERSITY SICHUAN UNIVERSITYInventors: Heping Xie, Mingzhong Gao, Ling Chen, Zhiyi Liao, Zhilong Zhang, Zetian Zhang, Yiqiang Lu, Cong Li, Zhiqiang He
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Patent number: 11781390Abstract: A fidelity retaining type coring device for a rock sample, comprising a rock core drilling tool, a rock core sample storage barrel, and a rock core sample fidelity retaining cabin.Type: GrantFiled: March 15, 2019Date of Patent: October 10, 2023Assignee: SHENZHEN UNIVERSITYInventors: Mingzhong Gao, Heping Xie, Ling Chen, Jianbo Zhu, Cunbao Li, Zhiyi Liao, Zhiqiang He, Jun Guo, Cong Li
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Patent number: 11585738Abstract: An apparatus for analyzing the content of at least one contaminant in a liquid cryogen comprising a cylindrical enclosure, an annular enclosure arranged around the cylindrical enclosure, means for dividing a flow of liquid cryogen in two, means for delivering a first part of the liquid cryogen to the cylindrical enclosure, means for delivering a second part of the liquid cryogen to the annular enclosure, a pipe connected to the cylindrical enclosure to allow vaporized liquid to pass through, a pipe connected to the annular enclosure to allow vaporized liquid to pass through, a heater for heating the cylindrical enclosure vessel and means for stopping the delivery of liquid cryogen to the cylindrical enclosure.Type: GrantFiled: May 18, 2018Date of Patent: February 21, 2023Assignee: L'Air Liquide Societe Anonyme Pour L'Etude Et L'Exploitation Des Procedes Georges ClaudeInventors: Patrick Le Bot, Frederic Crayssac, Benoit Davidian, Mathieu Leclerc
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Patent number: 11532861Abstract: A battery device and a method for producing a battery device for a motor vehicle. In said method, a cooling base element and a battery module are provided, and the battery module is mounted on the cooling base element, forming at least one gap between a battery module region and a cooling base region. A filling device is then coupled to at least one filling opening of at least one filling tube, with the at least one filling tube extending into the at least one gap, and a heat conducting medium is introduced from the filling device through the filling tube into the at least one gap.Type: GrantFiled: July 23, 2020Date of Patent: December 20, 2022Assignee: AUDI AGInventors: Marc Gormanns, Tobias Benker, Michael Frauenhofer, Oliver Schieler, Michael Schüßler
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Patent number: 11414758Abstract: A substrate holder 10 in the form of a mesh structure with a sample-receiving surface 10A is provided. The substrate holder 10 containing the samples 21 is at least partially folded and inserted into a substrate processing apparatus to produce coated samples 21A by directing at least one coating material P1, P2, . . . , Pn onto the samples through the mesh structure. A substrate processing system and a method for producing coated substrates are further provided.Type: GrantFiled: March 26, 2020Date of Patent: August 16, 2022Assignee: PICOSUN OYInventors: Juhana Kostamo, Väinö Kilpi, Riina Ritasalo
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Patent number: 11187633Abstract: An improved liquefied natural gas vaporization system is provided for converting liquefied natural gas (LNG) to vapor so that it can be measured for integrity. The liquefied natural gas vaporization system of the present invention makes use of a sample probe that uses a cryogenic check valve to allow the vaporization process to begin early, and, due to design and incorporation with heated regulation, reduces the need for an accumulator, which is often used in other systems. By eliminating the need for an accumulator, a more real-time and authentic measurement of the LNG sample may be taken. After the probe takes the sample, the sample is sent to a sampling system and subsequently to an analytical measuring system, where the sample is measured.Type: GrantFiled: September 18, 2019Date of Patent: November 30, 2021Assignee: Welker, Inc.Inventor: Josh H. Welker
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Patent number: 11143580Abstract: Provided is a material testing machine capable of giving an appropriate testing force to a testing piece. The material testing machine performs a three-point bending test on a testing piece and includes a support mechanism that supports the testing piece, an indenter that is connected to an ultrasonic oscillator and gives ultrasonic vibration to the testing piece by abutting against the testing piece, and a load mechanism that presses the indenter to the testing piece supported by the support mechanism. The support mechanism includes: a spherical seat that has a lower member equipped with a spherical-surface-shaped concave portion or convex portion, and an upper member equipped with a spherical-surface-shaped concave portion or convex portion having a shape corresponding to the concave portion or convex portion in the lower member; a holding portion; and a first movable member.Type: GrantFiled: May 28, 2020Date of Patent: October 12, 2021Assignee: Shimadzu CorporationInventor: Tadaoki Takii
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Patent number: 11136540Abstract: A flask assembly that includes: an Erlenmeyer flask; and a liner bag comprising a single opening the bag sized to fit within the flask and having a thickness from about 0.0254 mm to about 0.508 mm. The liner bag is configured for cell culturing and ease of insertion of the bag into the flask. In addition, the liner bag comprises a gas-permeable, polymeric material. Further, the liner bag can include a pocket adapted to receive a removable flask insertion element and/or at least one foldable seam configured to facilitate insertion of the bag into the flask. The liner bag can also include a vent having a gas permeability that is greater than the gas permeability of the gas-permeable, polymeric material employed in the balance of the bag.Type: GrantFiled: May 19, 2017Date of Patent: October 5, 2021Assignee: Corning IncorporatedInventor: William Joseph Lacey
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Patent number: 11101104Abstract: Cryo compatible sample grids having multi-modal cryo-EM compatible GUIDs, according to the present disclosure include an outer support structure that defines a region of the grid for holding one or more samples, and a plurality of inner support structures that define a plurality of apertures that are each configured to hold a sample. Cryo compatible sample grids further include a first identifier located on the outer support structure, and a second identifier located within the region of the grid for holding the one or more samples. The first identifier is readable with an optical detector, while the second identifier is readable with an electron detector (e.g., within an electron microscope). Specifically, the second identifier is readable with an electron detector when one or more teeth and/or holes that comprise the second identifier are filled with ice from a vitrification process.Type: GrantFiled: August 30, 2019Date of Patent: August 24, 2021Assignee: FEI CompanyInventors: Maarten Kuijper, Ondrej Ludmil Shanel, Mathijs Petrus van den Boogaard, Pleun Dona
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Patent number: 10463347Abstract: The present invention generally relates to devices and methods for collecting and stabilizing biological samples, and more particularly, for collecting and stabilizing blood or other bodily fluids from a user's fingertip, earlobe, heel or other locations. The present invention also relates to sample collection devices that simplify the process for mixing the biological samples with an additive or additives, provide for efficient storage and safe transport of the samples, and provide for easy access to the samples for subsequent processing.Type: GrantFiled: September 8, 2017Date of Patent: November 5, 2019Assignee: DXTERITY DIAGNOSTICS INCORPORATEDInventors: Robert Terbrueggen, Scott Gordon Beach
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Patent number: 10422728Abstract: A specimen extraction kit includes a flexible tubular container configured to contain an extraction liquid, two holding portions opposed to each other and arranged at opposite sides of the tubular container, a coupling portion that couples the opposing holding portions, and a bending rib arranged on each of the opposing holding portions and configured to bend the tubular container and an extraction subject.Type: GrantFiled: September 26, 2014Date of Patent: September 24, 2019Assignee: Denka Seiken Co.Inventors: Masashi Suzaki, Makoto Fukasawa, Yoshiaki Hirayama, Kazuhiro Akiishi
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Patent number: 9958362Abstract: A sample preparation device for electron microscopy (EM) that is configured to eliminate user-to-user variations and environment contaminations, which are often present in the conventional method of sample preparation. The device not only provides a means for evenly and reproducibly delivering a fluid or sample to an EM grid, but also provides a means for sealing the EM grid in an air-tight chamber and delivering air-sensitive samples to the EM grid. The platform may comprise readily fabricated glass chips with features integrated to preserve the integrity of the sample grid and to facilitate its extraction. The methods may eliminate the element of user dependent variability and thus improve the throughput, reproducibility and translation of these methods.Type: GrantFiled: September 13, 2016Date of Patent: May 1, 2018Assignee: The Florida State University Research Foundation, Inc.Inventors: Michael G. Roper, Nikita Mukhitov, Scott Stagg, John Spear
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Patent number: 9733156Abstract: Certain embodiments described herein are directed to sample platforms that are configured to permit electrical coupling between a sample support and electrical ground. In some examples, a sample platform configured to receive a sample support effective to retain a sample for direct sample analysis and comprising an aperture for receiving at least one electrical coupler configured to engage the sample support and provide electrical coupling between the sample support and ground is described.Type: GrantFiled: October 29, 2012Date of Patent: August 15, 2017Assignee: PerkinElmer Health Sciences, Inc.Inventors: Paul L. St. Cyr, Michael L. DelVecchio
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Patent number: 9534990Abstract: The present invention generally relates to systems and methods for preserving biological samples and, more particularly, an arrangement for drying biological samples disposed on sample storage substrates. The systems and methods for preserving biological samples can include a heating element such as a chemical heating pad that facilitates drying of the biological samples.Type: GrantFiled: March 15, 2012Date of Patent: January 3, 2017Assignee: GE Healthcare UK LimitedInventors: Michael John Smith, Stevan Paul Tortorella
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Patent number: 9161527Abstract: A system for using freezing, storing and thawing biopharmaceutical materials which includes a holder and a container for holding biopharmaceutical materials therein. The holder has a cavity and the container is received in the cavity. The holder includes a first portion and second portion. The container is received between the first portion and the second portion to connect the container to the holder. The holder includes an interior cradle having a bottom and edges extending from the bottom. The cradle bounds the cavity. An outer rim is connected to the cradle and separated from the cavity. The bottom includes an inner surface facing the cavity receiving the container and an outer surface. The outer surface of the bottom is recessed relative to an outer surface of the outer rim.Type: GrantFiled: June 23, 2011Date of Patent: October 20, 2015Assignee: SARTORIUS STEDIM NORTH AMERICA INC.Inventors: Jonathan Cutting, Isabelle Gay, Eric K. Lee, Nicolas Voute
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Publication number: 20150143924Abstract: Disclosed herein are a test apparatus of a fluidic sample, which tests the fluidic sample, and a control method thereof. The test apparatus of the fluidic sample includes a housing, an installing member in which a cartridge receiving a fluid is inserted, a pressing member which is disposed in the housing to press the cartridge and perform an inspection of the fluid, a driving unit of which at least a part is coupled to the pressing member so as to movably drive the pressing member, and a sensing unit of which at least a part is opposite to the driving unit so as to sense a position of the driving unit. According to the present invention, since the sensing unit can recognize the position of the driving unit, the pressing member can apply uniform pressure to the cartridge.Type: ApplicationFiled: December 2, 2013Publication date: May 28, 2015Applicant: SAMSUNG ELECTRONICS CO., LTD.Inventor: Hyun Suk KANG
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Patent number: 9010202Abstract: An improved cryogenic specimen holder for imaging and analysis facilitates imaging at very high tilt angles with a large field of view. A retractable specimen holder tip protects the specimen during transport. An optimized Dewar design is positioned at a fixed, tilted angle with respect to the axis of the holder, providing a means of continuously cooling the specimen irrespective of the high tilt angle and amount of liquid nitrogen present in the vessel. The Dewar neck design reduces entrapment of nitrogen gas bubbles and its shape prevents the spilling of liquid nitrogen at high tilt angles. The specimen holder has a retractable tip that completely encapsulates the specimen within a shielded environment internal to the specimen holder body. The cooling and specimen transfer mechanisms reduce thermal drift and the detrimental effects of vibrations generated by both the evaporation of liquid nitrogen present in the Dewar and other environmental effects.Type: GrantFiled: July 27, 2012Date of Patent: April 21, 2015Inventors: Halina Stabacinskiene, Jeffrey J. Gronsky, Christine M. Thomas, Pushkarraj V. Deshmukh, Alan C. Robins, Paul E. Fischione
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Publication number: 20150101422Abstract: The present invention relates to a sample analyzing chip. The chip can prevent upper and lower substrates of a channel from being attached to each other due to deflection on a micro channel and can solve the problem of the sample drying up within a measuring time of a target. Also, the chip can prevent bubbles from being generated in a central portion of the micro channel.Type: ApplicationFiled: May 14, 2013Publication date: April 16, 2015Applicant: NANOENTEK, INC.Inventors: Dae Sung Hur, Jae Jeong Kim, Yu Rae Kim
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Patent number: 9000397Abstract: A specimen holder and method for controlling the same, which can mount and fasten a specimen to allow observation thereof by joining a body and a stand of the specimen holder together. The specimen holder includes: a body; a specimen mounting part formed at an end of the body for fixing a specimen; elasticity means located inside the body; and a stand detachably joined with the body. The stand includes: a base part; and a joining part protrudingly formed on the upper face of the base part and having a through hole to which at least a part of the specimen mounting part is inserted. The specimen mounting part includes: a first grip part located at an end portion of the specimen mounting part for fixing one side of the specimen; and a second grip part movably connected with the elasticity means for fixing the other side of the specimen.Type: GrantFiled: October 21, 2013Date of Patent: April 7, 2015Assignee: Hitachi High-Technologies Korea Co., Ltd.Inventor: Heyoung Cheol Heyoung
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Publication number: 20150087052Abstract: A container includes an inner bag, where the interior of the inner bag includes a sterile environment for storing a material, at least one access port configured to provide fluid access to the interior of the inner bag, an overwrap bag, where the interior of the overwrap bag includes a sterile environment for storing the material and where the inner bag is enclosed within the interior of the overwrap bag, and an overwrap access port configured to provide fluid access to the interior of the overwrap bag. The material can include a biomaterial. Each of the inner bag, the overwrap bag, the at least one access port, and the overwrap access port can include a fluoropolymer such as fluoroethylenepropylene (FEP).Type: ApplicationFiled: September 23, 2014Publication date: March 26, 2015Inventors: Herbert CULLIS, Phillippe J. BROUSSARD
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Patent number: 8987682Abstract: A specimen positioning device (100) is for use in or with a charged particle beam system having a specimen chamber (1) and has: a base (10) provided with a hole (12) in operative communication with the specimen chamber (1); a specimen holder (20) movably mounted in the hole (12) and having a first portion (22) and a second portion (24); and a first portion support portion (40) supporting the first portion (22) in the specimen chamber (1). The second portion (24) supports the first portion (22) via a resilient member (34).Type: GrantFiled: December 10, 2013Date of Patent: March 24, 2015Assignee: JEOL Ltd.Inventor: Mitsuru Hamochi
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Patent number: 8956861Abstract: Provided are a container tray in which a position and orientation of a container is hardly displaced from a predetermined position and orientation; a tray base used together with the container tray; and an observation unit. The container tray 8 includes a mounting plate 81 having a mounting surface 811 on which the container is to be mounted, an elastic body 82, and a biasing mechanism 83, 842. The elastic body 82 is arranged on the mounting surface 811 of the mounting plate 81 around a mounting region R where the container is to be mounted. The biasing mechanism 83, 842 is capable of switching states between a biased state in which the elastic body 82 is biased inward by applying a pressing force to the elastic body 82 from outside and a bias released state in which the bias on the elastic body 82 is released.Type: GrantFiled: September 14, 2012Date of Patent: February 17, 2015Assignee: Panasonic Healthcare Holdings Co., Ltd.Inventor: Mikio Houjou
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Patent number: 8957778Abstract: The present invention uses a wireless memory/communication device at least on the one or more sample storage devices, preferably on both the one or more sample storage devices and the sampling holder, optionally the port on the equipment as well. Data such as that relating to the vessel, the location of the port on the vessel, the device, its manufacture date or lot number, the date of the installation, sterilization and/or taking of a sample along with the person who installed the device and/or took the sample can be read and preferably added to the wireless device when a read/write type of device as these events occur through a scanner/reader/writer device (fixed or hand held). The sample storage device in the laboratory can also then be read and recorded to track the sample storage device's life.Type: GrantFiled: July 18, 2008Date of Patent: February 17, 2015Assignee: EMD Millipore CorporationInventors: George Adams, John Dana Hubbard, Aaron Burke, Anthony DiLeo
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Publication number: 20150027208Abstract: The present invention relates to a method for stabilising fatty acids present in a sample such as bodily fluids. The present invention further relates to a solid medium which is capable of stabilising fatty acids applied thereto, and a method for preparing same. The present invention further relates to a method for determining the fatty acid composition of a sample.Type: ApplicationFiled: January 11, 2013Publication date: January 29, 2015Inventors: Robert Gibson, Liu Ge
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Publication number: 20150017680Abstract: The present invention relates to a device comprising a sample receiving appliance, a receiving appliance for test organisms, preferably for a suspension comprising test organisms, in particular for a bacterial suspension, and a jet pump appliance, wherein the jet pump appliance is, or can be brought, into active connection with the receiving appliance, and wherein the jet pump appliance is designed and installed in order, by means of a propellant medium having a higher pressure than atmospheric pressure at the location of installation of the device to spray test organisms in the form of an aerosol in the direction of the sample receiving installation, wherein the device has an installation for controlling a reproducible pressure of the propellant medium during the spraying of the test organisms and also the use of a device according to the invention.Type: ApplicationFiled: March 1, 2013Publication date: January 15, 2015Inventors: Thorsten Steinberg, Ali Al-Ahmad, Karen Lienkamp, Norbert Nanko
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Patent number: 8925397Abstract: A vertical clamping device is provided that supports a flow cell component in a vertical configuration in which the flow cell is on an opposite side of the vertical support from the electronic interface. The clamp includes a vertical setting to receive the flow cell component and provides an electronic interface on a vertical surface of the vertical setting. A block supports the fluidics interface and can move in a horizontal direction bringing the fluidics interface into contact with the flow cell component.Type: GrantFiled: August 30, 2013Date of Patent: January 6, 2015Assignee: Life Technologies CorporationInventor: David M. Cox
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Publication number: 20140373644Abstract: Described are sample carriers and methods of extracting a fluid sample from a dried sample on a sample carrier. The sample carrier has a first carrier portion that receives a fluid sample, and includes a material that adsorbs the fluid sample and dissolves upon application of a solvent. A second carrier portion is attached to the first carrier portion and includes a material that is indissolvable in the solvent. The first carrier portion having a dried sample is dissolved into a solution upon application of the solvent. The solution can be analyzed to determine constituents in the extracted sample. The sample carrier can conveniently be in the form of a card or a dipstick. In alternative embodiments, a carrier portion that includes the dried sample is indissolvable in the solvent but is released from another carrier portion through application of a solvent to an intervening dissolvable carrier portion.Type: ApplicationFiled: February 1, 2013Publication date: December 25, 2014Applicant: Water Technologies CorporationInventors: Pamela C. Iraneta, Kevin D. Wyndham, Moon Chul Jung
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Publication number: 20140373645Abstract: A fluid sample collection card assembly in one embodiment includes a case including a tray assembly receiving cavity accessible through a mouth portion of the case, and a tray assembly, the tray assembly including an absorbent layer supported by a base portion, the base portion including (i) a tray portion configured to be removably received within the tray assembly receiving cavity and (ii) a faceplate portion configured to at least substantially close the mouth when the tray portion is received within the tray assembly receiving cavity.Type: ApplicationFiled: June 19, 2013Publication date: December 25, 2014Applicant: Advance Dx, Inc.Inventor: Ned Bedrio
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Publication number: 20140373646Abstract: Provided is a sample fixing member for a time-of-flight secondary ion mass spectrometer that: can prevent the contamination of a solid sample; can stably fix the solid sample; and enables accurate detection of a secondary ion in a time-of-flight secondary ion mass spectrometer. A sample fixing member for a time-of-flight secondary ion mass spectrometer of the present invention includes a fibrous columnar structure including a plurality of fibrous columnar objects each having a length of 200 ?m or more.Type: ApplicationFiled: January 29, 2013Publication date: December 25, 2014Applicant: NITTO DENKO CORPORATIONInventor: Youhei Maeno
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Patent number: 8915154Abstract: A system and method for the automated preparation of one or more samples for analysis is disclosed. The system comprises a processing mechanism configured to process the one or more samples, wherein each sample is contained in a separate sample container. The system further comprises a cover configured to enclose the sample containers while the processing mechanism is operating, a first holder comprising a first pivot point and a second pivot point, wherein the first pivot point of the first holder is hingedly connected to the cover, a second holder comprising a first pivot point and a second pivot point, wherein the first pivot point of the second holder is hingedly connected to the cover, a first actuator interface arm hingedly connected to the second pivot point of the first holder, and a second actuator interface arm hingedly connected to the second pivot point of the second holder.Type: GrantFiled: July 30, 2012Date of Patent: December 23, 2014Assignee: Pioneer Hi Bred International IncInventors: Kenneth J. Ross, Keith J. Quanbeck, Gang Wan, Jeffrey D. Wille
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Publication number: 20140366739Abstract: A sample dispatcher is disclosed and is configured for individually introducing a plurality of portions of one or more sample fluids into a flow of a mobile phase of a liquid separation system. The liquid separation system is configured for separating compounds of the sample fluids and comprises a mobile phase drive configured for driving the mobile phase through a separation unit configured for separating compounds of the sample fluids in the mobile phase. The sample dispatcher comprises one or more sample reservoirs, each configured for receiving and temporarily storing a respective sample fluid portion or at least a part thereof, and a bypass channel.Type: ApplicationFiled: April 14, 2014Publication date: December 18, 2014Applicant: Agilent Technologies, Inc.Inventors: Klaus Witt, Konstantin Choikhet, Dwight Stoll
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Publication number: 20140366656Abstract: Described is a device for solid phase extraction of a dried sample of a biological fluid. The device includes a support structure such as a plate or support block that has a first side to receive a dried sample card. The support structure also has a second side that is opposite the first side and a number of apertures that extend between the first and second sides. The device also includes a plurality of wells each containing a sample preparation material and having an inlet end that communicates with a respective aperture at the second side of the support structure. Each dried sample on the dried sample card is aligned with one of the apertures. Extraction samples in each well pass through the sample preparation material, such as a chromatographic sorbent, in the well to remove one or more constituents of the extraction sample.Type: ApplicationFiled: September 18, 2012Publication date: December 18, 2014Inventors: Darryl W. Brousmiche, Pamela C. Iraneta, Erin E. Chambers, Moon Chul Jung
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Patent number: 8904886Abstract: A moveable end (ME) sample cylinder device is provided which employs a method of collection wherein the initial cylinder volume of the collection vessel or sampling cylinder is zero. The sample cylinder is inserted into the pressurized gas (or fluid) source for spot sampling thereof, said sample cylinder employing a piston or moveable end configured such that purging of the cylinder sample cavity is not required, since the sample cavity volume is essentially eliminated prior to sampling by the location of the piston within the cavity, the cavity expanding upon sampling via piston movement within the cavity. Also contemplated is a cap/body (CB) spot sample cylinder having a low internal volume and which can be inserted into a pressurized process through common valving. Insertion of the CB sample cylinder into the process eliminates purging of interconnecting tubing and also eliminates the impact of low ambient temperatures which can otherwise alter the spot sample composition.Type: GrantFiled: December 14, 2010Date of Patent: December 9, 2014Assignee: A+ Manufacturing LLCInventor: Donald P Mayeaux
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Publication number: 20140352456Abstract: A storage system for storing samples, such as frozen biological samples in RFID-tagged vials. The storage system has a plurality of lowest-level containers, such as sample boxes; a plurality of mid-level containers, such as shelves and racks; and a highest-level container, such as a mechanical freezer. Each lowest-level container receives a plurality of samples in a corresponding plurality of storage locations, each mid-level container receives two or more lowest-level containers, and the highest-level container receives the two or more mid-level containers. Each mid-level container and each lowest-level container has a corresponding indicator device. A controller sub-system tracks the locations of samples stored in the storage system.Type: ApplicationFiled: August 19, 2014Publication date: December 4, 2014Inventor: Hananel Davidowitz
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Publication number: 20140318281Abstract: The disclosed invention is an adapter apparatus for associating a fluid meter to the flow path of a fluid meter test bench. The apparatus comprises a saddle to hold and align the meter in position until a clamping force is applied to the meter to securely associated the meter under test with the test bench. A half dove tail grove and o-ring are used to reduce the clamping pressure required to create a fluid tight seal.Type: ApplicationFiled: April 15, 2014Publication date: October 30, 2014Inventor: Floyd Stanley Salser, JR.
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Publication number: 20140318282Abstract: A closure and method of making a closure are disclosed. The closure includes a cap body having a top portion and an opening extending therethrough defining a cavity in communication with said opening. A flow channel is defined within a portion of the cap body having an inlet and an outlet. A stopper is disposed within the cavity adjacent the outlet of the flow channel. The stopper is formed from a material adapted for flowing through the flow channel to form a pierceable portion, with at least one of the cap body and the stopper configured for closing a container.Type: ApplicationFiled: July 10, 2014Publication date: October 30, 2014Inventors: Alex Blekher, Bradley M. Wilkinson, Craig Owen Russ
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Patent number: 8857282Abstract: A method and sample holding assembly are described for use in the preparation of samples for analysis. The method comprises the steps of collecting a sample in a concentration tube which is open at one end and closed at the other, the closed end being selectively openable. A vial is coupled to the open end, the tube is inverted, the closed end is opened, and then solvent is evaporated from the sample via the opened end until the concentrated sample is confined to the vial. A sample holding assembly for use in the present method is also described. It comprises a concentration tube, and an adaptor arrangement for coupling a vial to the open end of the tube and defining a fluid path between the tube and the vial.Type: GrantFiled: March 29, 2010Date of Patent: October 14, 2014Assignee: Genevac LimitedInventor: Roger Lee-Smith
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Publication number: 20140298926Abstract: Disclosed is a biological sample holder, a container for storing multiple holders, and an automated holder retrieval system. The sample holder may comprise an elongate generally planar support including a handle end and an opposing biological sample storage end, wherein, a substrate for accepting a biological sample is mounted to the holder at said sample storage end. Optionally the substrate is so mounted within a recess in the surface of the support and the recess has a local surface providing a reaction surface for allowing a sub-sample to be removed from the medium by mechanical action, such as cutting or punching. The container may include an array of wells each well being generally square or rectangular in plan and the holders dimensioned so that they are held diagonally in a respective well.Type: ApplicationFiled: November 30, 2012Publication date: October 9, 2014Applicant: GE HEALTHCARE UK LIMITEDInventors: Michael Kenneth Kenrick, Geraint Seymour
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Publication number: 20140287487Abstract: This disclosure is directed to a cap for obtaining a target analyte from a suspension. The cap introduces a magnetic field or a magnetic gradient to the tube to draw the target analyte bound to a particle to the cap. In one aspect, a cap includes a magnetic insert and a receiving piece. The magnetic insert includes a stopper and a magnet extending from the stopper; and, the receiving piece, which is configured to hold the magnetic insert, includes a receiving stopper and a sheath. The sheath may include imaging slides on opposite sides of the sheath. In another aspect, the cap may include a stopper and an embedded magnet. The cap may include an analysis piece on a bottom end of the stopper. In yet another aspect, the cap may include a fluid compartment and a filter at a bottom end of the stopper.Type: ApplicationFiled: March 14, 2014Publication date: September 25, 2014Applicant: RareCyte, Inc.Inventors: Daniel Campton, Jackie Lynn Stilwell, Arturo Ramirez, Jennifer Chow
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Publication number: 20140260700Abstract: Provided herein are compositions and methods useful for preparing and analyzing a sample on a substrate by matrix assisted laser desorption ionization (MALDI) mass spectrometry (MS). In some embodiments, compositions provided herein comprise a substrate, matrix and nanoparticles, and sometimes comprise one or more additives and sometimes an analyte. Compositions provided herein sometimes comprise nanoparticles that include or are made up of silicon dioxide.Type: ApplicationFiled: March 13, 2013Publication date: September 18, 2014Applicant: SEQUENOM, INC.Inventors: BECKER Thomas, Stefan Berkenkamp
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Publication number: 20140251033Abstract: An apparatus for holding a sample tube includes a plurality of rollers circumscribing a clearance space along a central axis, and an actuator configured for moving the rollers between a non-gripping position and a gripping position. At the non-gripping position, the rollers are oriented relative to the central axis such that a diameter of the clearance space is at a maximum; and at the gripping position, the rollers are at a twisted angle relative to the central axis, and the diameter is reduced such that the rollers contact the sample tube.Type: ApplicationFiled: March 11, 2013Publication date: September 11, 2014Applicant: AGILENT TECHNOLOGIES, INC.Inventor: Seiji Unno
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Publication number: 20140257749Abstract: A dietary measurement system and a method of correlating dietary information to a defined volume of a measuring device are provided to reduce the effort and time necessary to keep track of the nutritional intake. The dietary measurement system comprises at least a measuring device adapted to accommodate food having multiple measurement indicators representing defined volumes, a nutrition database comprising dietary contents information for food and a mapping device. The mapping device comprises an input interface for receiving food selection information and a mapping processor, connected with said input interface and said nutrition database, said mapping processor being adapted to generate dietary correlation data from said dietary contents information, said dietary correlation data providing a reference between one of said measurement indicators of said measuring device and a given dietary contents level for food according to said food selection information.Type: ApplicationFiled: March 7, 2013Publication date: September 11, 2014Inventor: George Alexander Nathanson
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Publication number: 20140230579Abstract: A multiple layer cytometric test card includes a waste channel to receive biological waste from an area of the test card utilized for testing biological samples, a first waste storage compartment in a waste layer of the card having a top and a bottom in relation to an operating vertical orientation of the test card, and a capillary positioned along a vertical length of the first waste storage compartment, the capillary being open to the waste compartment along the vertical length of the waste compartment, wherein the waste channel is coupled to the capillary channel proximate the top of the waste storage compartment.Type: ApplicationFiled: February 15, 2013Publication date: August 21, 2014Applicant: Honeywell International Inc.Inventors: Danqing Zhang, Chen Zhou Ye, Ming Ge, Guan Tien GT Tan
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Publication number: 20140211206Abstract: According to an example, an apparatus for collecting a material to be spectrally analyzed includes a body having a first end and a second end, in which the body is elongated along a first axis from the first end to the second end. The body also includes a hole having an opening formed in an external surface of the body at a location between the first end and the second end and extending at least partially through the body at an angle with respect to the first axis. The body further includes a plurality of surface-enhanced spectroscopy (SES) elements positioned inside the body.Type: ApplicationFiled: January 25, 2013Publication date: July 31, 2014Applicant: Hewlett-Packard Development Company, L.P.Inventors: Shih-Yuan Wang, Huei Pei Kuo, Zhiyong Li, Gary Gibson