Nonplant Protein Is Expressed From The Polynucleotide Patents (Class 800/288)
  • Patent number: 11162108
    Abstract: Methods and materials for modulating biomass levels in plants are disclosed. For example, nucleic acids encoding biomass-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased biomass levels and plant products produced from plants having increased biomass levels.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: November 2, 2021
    Assignee: Ceres, Inc.
    Inventors: Chuan-Yin Wu, Han-Suk Kim, Gerard Magpantay, Fasong Zhou, Julissa Sosa, Gregory Nadzan, Roger I. Pennell, Mircea Achiriloaie, Wuyi Wang
  • Patent number: 11098322
    Abstract: This invention relates in part to plant breeding and herbicide tolerant plants. This invention includes a novel aad-1 transformation event in corn plants comprising a polynucleotide sequence, as described herein, inserted into a specific site within the genome of a corn cell. In some embodiments, said event/polynucleotide sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. Additionally, the subject invention provides assays for detecting the presence of the subject event in a sample (or corn grain, for example). The assays can be based on the DNA sequence of the recombinant construct, inserted into the corn genome, and on the genomic sequences flanking the insertion site. Kits and conditions useful in conducting the assays are also provided.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: August 24, 2021
    Assignee: DOW AGROSCIENCES LLC
    Inventors: Yunxing Cory Cui, Jill Bryan, Donald Maum, Greg Gilles, Terry Wright, Jennifer Hamilton, Nicole Arnold, Nathan VanOpdorp, Tina Kaiser, Ning Zhou
  • Patent number: 11085049
    Abstract: A method of producing a virus like particle (VLP) in a plant comprising modified hemagglutinin is provided. The method comprises introducing a nucleic acid comprising a regulatory region active in the plant and operatively linked to a nucleotide sequence encoding a modified influenza hemagglutinin (HA) protein into the plant, or portion of the plant, the modified HA protein comprises a modified proteolytic loop. Followed by incubating the plant or portion of the plant under conditions that permit the expression of the nucleic acids, thereby producing the VLP. The modified proteolytic loop may comprise one or more protease cleavage sites exhibiting reduced or abolished cleavage by a protease. The nucleotide sequence encoding the HA may be selected from the group consisting of B HA, C, H1, H2, H3, H4, H5, H6, H7, H8, H9, H10, H11, H12, H13, H14, H15, and H16. Also described is a virus like particle (VLP) produced by the method, and plants expressing the VLP.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: August 10, 2021
    Assignee: MEDICAGO INC.
    Inventors: Manon Couture, Marc-Andre D'Aoust, Louis-Philippe Vezina
  • Patent number: 11078492
    Abstract: Provided are methods of increasing nitrogen use efficiency, yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality and/or abiotic stress tolerance of a plant by expressing within the plant an exogenous polynucleotide comprising a nucleic acid sequence at least 80% identical to SEQ ID NO: 387, 1-386, 388-469, 763-3704 and 3705; or an exogenous polynucleotide encoding a polypeptide at least 80% identical to SEQ ID NO: 602, 470-601, 603-762, 3706-5858, 5860-5910, 5912, 5914-5923, 5925-6046 or 6047. Also provided is an isolated polynucleotide comprising a nucleic acid sequence selected from the group consisting of SEQ ID NOs: 387, 1-386, 388-469, 763-3704 and 3705, which can be used to increase the nitrogen use efficiency, yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality and/or abiotic stress tolerance of a plant.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: August 3, 2021
    Assignee: Evogene Ltd.
    Inventors: David Panik, Basia Judith Vinocur, Hagai Karchi
  • Patent number: 11034742
    Abstract: The present invention relates to isolated variants of an antimicrobial peptide plectasin, comprising a substitution at positions 9, 13 and 32, wherein the variant has antimicrobial activity and methods for treatment of treatment of diseases mediated by Mycobacterium tuberculosis and gram-positive bacteria.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: June 15, 2021
    Assignee: LINNANE PHARMA AB
    Inventors: Gabriela Zuzana Victoria Godaly, Erik Axel Mattias Sturegard, Erik Olof Tenland
  • Patent number: 10947552
    Abstract: Provided herein are compositions and methods for producing milk proteins in plants, which allow for safe, sustainable and humane production of milk proteins for commercial use, such as use in food compositions. The disclosure provides recombinant fusion proteins comprising a milk protein, or fragment thereof and a structured mammalian, avian, plant, or fungal protein, or fragment thereof. The disclosure also provides methods for producing the recombinant fusions proteins, and food compositions comprising the same.
    Type: Grant
    Filed: September 30, 2020
    Date of Patent: March 16, 2021
    Assignee: Alpine Roads, Inc.
    Inventors: Viviane Lanquar, Magi El-Richani
  • Patent number: 10947558
    Abstract: RNAi compositions and methods are provided which inhibit soybean nematode cyst infestation. Also disclosed are plants comprising said RNAi.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: March 16, 2021
    Assignee: Rutgers, The State University of New Jersey
    Inventor: Rong Di
  • Patent number: 10889826
    Abstract: Methods and compositions for producing epidermal growth factor (EGF) in soybean seeds featuring the use of transgenic soybean seeds expressing a seed-specific codon optimized gene encoding of the hEGF protein. Using these methods, the production of hEGF is sufficient and the activity of the EGF protein is comparable to commercially available EGF. The present invention shows the feasibility of using soybean seeds as a biofactory to produce therapeutic agents for a delivery platform, e.g., in a soymilk delivery platform.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: January 12, 2021
    Assignees: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA, WASHINGTON UNIVERSITY
    Inventors: Eliot Herman, Monica Schmidt, Brad W. Warner
  • Patent number: 10883089
    Abstract: The invention relates to feruloyl-CoA:monolignol transferase enzymes and nucleic acids encoding the feruloyl-CoA:monolignol transferase enzymes. The enzymes and/or the nucleic acids enable incorporation of monolignol ferulates into the lignin of plants. The monolignol ferulates include, for example, p-coumaryl ferulate, coniferyl ferulate, and/or sinapyl ferulate.
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: January 5, 2021
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: John Ralph, Steven D. Karlen, Rebecca Anne Smith, Brian Fox, Emily Beebe, Craig Bingman
  • Patent number: 10829776
    Abstract: Provided are methods of increasing nitrogen use efficiency, fertilizer use efficiency, yield, growth rate, vigor, biomass, oil content and/or abiotic stress tolerance of a plant by expressing within the plant an exogenous polynucleotide comprising a nucleic acid sequence encoding a polypeptide at least 80% identical to SEQ ID NO: 2560, 2557, 184, 238, 188, 154-156, 158-161, 163-183, 185-187, 189-197, 200-237, 239-264, 266-269, 1351, 1365-1425, 1429-1457, 1459, 1461-1730, 1735, 1739-2397, 2533-2541, 2544-2556, 2558, 2559, 2561-2562 or 2563. Also provided are isolated polynucleotides and polypeptides which can be used to increase nitrogen use efficiency, fertilizer use efficiency, yield, growth rate, vigor, biomass, oil content and/or abiotic stress tolerance of a plant of a plant.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: November 10, 2020
    Assignee: Evogene Ltd.
    Inventors: Basia Judith Vinocur, Sharon Ayal, Alex Diber, Eyal Emmanuel, Gil Ronen, Michael Gang, Dotan Dimet, Hagai Karchi, Yoav Herschkovitz
  • Patent number: 10719774
    Abstract: This disclosure relates generally to health monitoring of systems, and more particularly to monitor health of a system for fault signature identification. The system estimates Health Index (HI) of the system as time series data. By analyzing data corresponding to the estimated HI, the system identifies one or more time windows in which majority of the estimated HI values are low as a low HI window, and one or more time windows in which majority of the estimated HI values are high as a high HI window. Upon identifying a low HI window, which indicates an abnormal behavior of the system being monitored, based on a local Bayesian Network generated for the system being monitored, an Explainability Index (EI) for each sensor is generated, wherein the EI quantifies contribution of the sensor to the low HI. Further, associated component(s) is identified as contributing to abnormal/faulty behavior of the system.
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: July 21, 2020
    Assignee: Tata Consultancy Services Limited
    Inventors: Pankaj Malhotra, Vishnu T V, Narendhar Gugulothu, Lovekesh Vig, Puneet Agarwal, Gautam Shroff
  • Patent number: 10696980
    Abstract: The present invention relates to a method of increasing resistance against soybean rust in transgenic plants and/or plant cells. In these plants, the content and/or the activity of an ADR-1-protein are increased in comparison to the wild-type plants not including a recombinant ADR-1-gene.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: June 30, 2020
    Assignee: BASF Plant Science Company GmbH
    Inventor: Holger Schultheiss
  • Patent number: 10685288
    Abstract: Method for configuring an apparatus or method for prediction of a malfunction of a unit, includes providing components of the unit; providing single malfunctions for each component; providing probabilities for the single malfunctions of each component; providing a parameter of each component for each single malfunction of this component; dividing each parameter into discrete value states; providing values of the parameters; determining a transition matrix for each parameter on the basis of the measurements of this parameter, wherein the transition matrix includes for the plurality of discrete value states of each parameter the probabilities to switch from one of the discrete value states to another of the discrete value states within a certain time period; determining the probabilities of the discrete value states on the basis of the measurements of the parameters; and providing the conditional probabilities of the discrete value states given the corresponding single malfunction.
    Type: Grant
    Filed: August 3, 2015
    Date of Patent: June 16, 2020
    Assignee: CASSANTEC AG
    Inventor: Frank Kirschnick
  • Patent number: 10301643
    Abstract: Transgenic seed for crops with improved traits are provided by trait-improving recombinant DNA where plants grown from such transgenic seed exhibit one or more improved traits as compared to a control plant. Also provided are methods of making transgenic plants with recombinant DNA and the one or more improved traits and methods of using those plants.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: May 28, 2019
    Assignee: Monsanto Technology LLC
    Inventors: Mark Scott Abad, Barry S. Goldman, Balasulojini Karunanandaa, Angela Ferguson, Erin Naymark, Mahmood Sayed, Daniel Riggsbee, Maria McDonald, Bettina Darveaux, Jaclyn Cleveland
  • Patent number: 10246721
    Abstract: A novel class of transporter protein, referred to as SWEET, GLUE or Glü, is disclosed. These transporters provide a novel system for the transportation of sugars across membranes within a cell and between the inside and outside of a cell. Such transporters are useful for understanding and altering the sugar concentration within certain organs of an organism, and within certain organelles within the cell. These transporters are also useful in protecting plants from a pathogen attack.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: April 2, 2019
    Assignee: Carnegie Institution of Washington
    Inventors: Wolf B. Frommer, Sylvie Lalonde
  • Patent number: 10227605
    Abstract: The invention relates to a polypeptide for regulating agronomic characters and yield characters of plants and application thereof. The invention alters agronomic characters and yield characters of plants such as root development, tillering ability, heading period, panicle structure, grains number per panicle, grain morphology, and 1000 grains weight by directional regulating expression level of cytokinin-O-glycosyltransferase 1 in plants, thus achieve the aim of modifying plant type, panicle structure, grain morphology and weight, increasing yield.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: March 12, 2019
    Assignee: SHANGHAI INSTITUTES FOR BIOLOGICAL SCIENCES, CHINESE ACADEMY OF SCIENCES
    Inventors: Fangqing Guo, Xiaoling Shang, Hua Tian
  • Patent number: 10227604
    Abstract: The present invention relates to a plant for producing a protein containing a humanized low-mannose N-glycan, and a method for producing a protein containing a customized humanized low-mannose N-glycan using the aforementioned plant.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: March 12, 2019
    Assignee: INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY
    Inventors: Kyun Oh Lee, Jae Yong Yoo, Ki Seong Ko, Sang Yeol Lee
  • Patent number: 10196664
    Abstract: The invention provides methods for reducing the levels of alfa (1,3)-fucosylated N-glycans on glycoproteins produced in plants or plant cells. In addition, the invention provides alfa(1,3)-fucosyltransferase genes from Nicotiana benthamiana, and mutant N. benthamiana plants in which the levels of alfa(1,3)-fucosylated N-glycans are reduced.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: February 5, 2019
    Assignee: Icon Genetics GmbH
    Inventors: Koen Weterings, Gerben Van Eldik
  • Patent number: 10174335
    Abstract: An isolated nucleic acid molecule is provided comprising a nucleotide sequence which encodes a glutamine:fructose-6-phosphate amidotransferase from E. coli which is particularly suitable for expression in cotton plant cells. The invention also relates to plant cells or plants, in particular to cotton plant cells or cotton plants which produce an increased amount of positively charged polysaccharides in their cell walls. Furthermore methods and means are provided to increase the content of positively charged polysaccharides in the cell walls of cotton cells, in particular in cotton fibers. Fibers obtained from such cotton plants have an altered chemical reactivity which can be used to attach reactive dyes or other textile finish reagents to these fibers.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: January 8, 2019
    Assignee: BASF SE
    Inventor: Frank Meulewaeter
  • Patent number: 10065993
    Abstract: The present invention relates to a peptide which consists of more than 50% of sequence sections of the formula -(An-Bm-Co)-, and to a conjugate containing the peptide and at least one covalently bonded active compound, and to a process for the preparation of the conjugate. The present invention furthermore relates to the use of the peptide and the conjugate for targeting of the kidney, and to a medicament comprising the peptide or conjugate.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: September 4, 2018
    Assignee: MERCK PATENT GMBH
    Inventors: Armin Kuebelbeck, Gregor Larbig, Stefan Arnold, Walter Mier
  • Patent number: 10065989
    Abstract: The present invention relates to compositions which may comprise a molecular sled linked to cargo and uses thereof. In particular, the present invention relates to a non-naturally occurring or engineered composition which may comprise a molecular sled, linkers and a molecular cargo connected to the sled via the linkers. Methods involving the use of molecular sleds and their cargoes and pharmaceutical compositions, methods for treating cancer, a degenerative disease, a genetic disease or an infectious disease as well as diagnostic methods are also contemplated by the present invention.
    Type: Grant
    Filed: January 13, 2015
    Date of Patent: September 4, 2018
    Assignees: The Broad Institute Inc., President and Fellows of Harvard College, Rijksuniversiteit Groningen
    Inventors: Walter F. Mangel, Paul Blainey, Vito Graziano, Andreas Herrmann, William J. McGrath, Antonius Martinus Van Oijen, Xiaoliang Sunney Xie
  • Patent number: 10035991
    Abstract: The present invention relates to the production of a non-transgenic plant resistant or tolerant to a herbicide of the phosphonomethylglycine family, e.g., glyphosate. The present invention also relates to the use of a recombinagenic oligonucleobase to make a desired mutation in the chromosomal or episomal sequences of a plant in the gene encoding for 5-enol pyruvylshikimate-3-phosphate synthase (EPSPS). The mutated protein, which substantially maintains the catalytic activity of the wild-type protein, allows for increased resistance or tolerance of the plant to a herbicide of the phosphonomethylglycine family, and allows for the substantially normal growth or development of the plant, its organs, tissues or cells as compared to the wild-type plant irrespective of the presence or absence of the herbicide.
    Type: Grant
    Filed: November 16, 2007
    Date of Patent: July 31, 2018
    Assignee: CIBUS US LLC
    Inventors: Peter R. Beetham, Patricia L. Avissar, Keith A. Walker, Richard A. Metz
  • Patent number: 9938537
    Abstract: Methods and compositions for increasing a plant's resistance to an insect pest such as the corn rootworm are provided. Methods are provided for overexpression of Crw2, or variants thereof, in a host plant or plant cell to increase resistance to an insect pest in a plant such as maize. Methods are also provided for identifying variants of Crw2 that when incorporated into a plant via transgenic or traditional breeding means increase resistance to an insect pest in a plant such as maize. Also provided are methods for increasing resistance by overexpressing Crw1 and Crw2.
    Type: Grant
    Filed: September 20, 2013
    Date of Patent: April 10, 2018
    Assignees: Purdue Research Foundation, Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and Company
    Inventors: Gurmukh S. Johal, Bailin Li, Dilbag S. Multani
  • Patent number: 9932611
    Abstract: Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as succinate. Also provided herein are methods for using such an organism to produce succinate.
    Type: Grant
    Filed: October 21, 2013
    Date of Patent: April 3, 2018
    Assignee: Genomatica, Inc.
    Inventors: Anthony P. Burgard, Robin E. Osterhout, Stephen J. Van Dien, Cara Ann Tracewell, Priti Pharkya, Stefan Andrae
  • Patent number: 9827280
    Abstract: Transgenic microalgae expressing at least one exogenous biologically active protein. The protein-expressing microalgae are used for the oral delivery of the biologically active protein to the target organism in its intact and functional form. The exogenous protein, expressed in algae, is characterized by being biologically active, exerting at least one specific activity having a beneficial effect on the subject consuming the algae. The transgenic microalgae are used as animal food for aquatic or land animals welfare or as food supplement for human healthcare.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: November 28, 2017
    Assignee: TRANSALGAE ISRAEL LTD.
    Inventors: Shiri Moshitzky, Doron Eisenstadt, Guy Levi, Ofra Chen
  • Patent number: 9816104
    Abstract: Methods and compositions for deploying refuge seeds together with transgenic crop seeds are provided. The refuge seeds can be non-transgenic seeds of a similar variety to that of the transgenic crop seeds, or the refuge seeds can be a transgenic variety.
    Type: Grant
    Filed: December 31, 2009
    Date of Patent: November 14, 2017
    Assignee: Monsanto Technology LLC
    Inventors: Jay C. Pershing, Eric S. Sachs, Ernest F. Sanders
  • Patent number: 9714416
    Abstract: The present invention relates enzyme composition comprising a cellulolytic preparation and an acetylxylan esterase (AXE); and the used of cellulolytic enzyme compositions for hydrolyzing acetylated cellulosic material. Finally the invention also relates to processes of producing fermentation products from acetylated cellulosic materials using a cellulolytic enzyme composition of the invention.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: July 25, 2017
    Assignee: Novozymes A/S
    Inventors: Prashant Iyer, Armindo Ribiero Gaspar, James Croonenberghs, Thomas P. Binder
  • Patent number: 9624504
    Abstract: Isolated polynucleotides and polypeptides and recombinant DNA constructs useful for conferring drought tolerance, compositions (such as plants or seeds) comprising these recombinant DNA constructs, and methods utilizing these recombinant DNA constructs. The recombinant DNA construct comprises a polynucleotide operably linked to a promoter that is functional in a plant, wherein said polynucleotide encodes a DTP6 polypeptide.
    Type: Grant
    Filed: October 28, 2011
    Date of Patent: April 18, 2017
    Assignees: E I DU PONT DE NEMOURS AND COMPANY, PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Stephen M Allen, Jason L Brothers, Krupa Deshmukh, Honor Renee Lafitte, Xiao-Yi Li, Cheng Lu, Stanley Luck, Jeffrey Mullen, Hajime Sakai, James J Saylor, Scott V Tingey, Robert Wayne Williams
  • Patent number: 9611298
    Abstract: Charged nutritive proteins are provided. In some embodiments the nutritive proteins an aqueous solubility of at least 12.5 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 50 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 100 g/L at pH 7.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: April 4, 2017
    Assignee: Axcella Health Inc.
    Inventors: David Arthur Berry, Brett Adam Boghigian, Nathaniel W. Silver, Geoffrey von Maltzahn, Michael Hamill, Rajeev Chillakuru, John F. Kramarczyk
  • Patent number: 9611460
    Abstract: Nucleic acid molecules encoding polypeptides having polyketide synthase activity have been identified and characterized. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: April 4, 2017
    Assignees: NATIONAL RESEARCH COUNCIL OF CANADA, UNIVERSITY OF SASKATCHEWAN
    Inventors: Jonathan E. Page, Steve Gagne
  • Patent number: 9534230
    Abstract: Stress tolerance in plants and plant cells is achieved by using nucleotide sequences encoding enzymes involved in the NAD salvage synthesis pathway and/or the NAD de novo synthesis pathway e.g. for overexpression in plants.
    Type: Grant
    Filed: August 11, 2014
    Date of Patent: January 3, 2017
    Assignee: Bayer CropScience N.V.
    Inventors: Marc De Block, Michael Metzlaff, Véronique Gossele
  • Patent number: 9493782
    Abstract: The plant promoter of a CBSU-Anther_Subtraction library (CAS1) gene encoding a mannitol dehydrogenase, and fragments thereof, and their use in promoting the expression of one or more heterologous nucleic acid fragments in an inducible manner in plants are described. These promoter fragments are also useful in creating recombinant DNA constructs comprising nucleic acid sequences encoding a desired gene product operably linked to such promoter fragments which can be utilized to transform plants and bring the expression of the gene product under external chemical and/or heat control in monocotyledonous and dicotyledonous plants.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: November 15, 2016
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Andrew Mark Cigan, Erica Unger-Wallace
  • Patent number: 9447424
    Abstract: The invention relates to gene expression regulatory sequences from soybean, specifically to the promoter of a soybean ATP sulfurylase (ATPS) and fragments thereof and theft use in promoting the expression of one or more heterologous nucleic acid fragments in a tissue-independent or constitutive manner in plants. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds containing the recombinant construct with the promoter, and methods for preparing and using the same.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: September 20, 2016
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventor: Zhongsen Li
  • Patent number: 9434929
    Abstract: The present invention discloses novel polypeptides and enzyme preparations containing them, which improve the efficiency of cellulose and lignocellulose degradation even at elevated temperatures. The polypeptides can be produced using conventional recombinant DNA technologies. The related polynucleotides, vectors and host cells are also disclosed. The polypeptides and the enzyme preparations containing them are particularly useful in improving the efficiency of cellulose and lignocellulose degradation, in improving the quality of animal feed, in machine dishwashing applications, in detergent compositions, in pulp and paper, textile, food, baking or beverage industry.
    Type: Grant
    Filed: October 23, 2013
    Date of Patent: September 6, 2016
    Assignee: Roal Oy
    Inventors: Kristiina Jarvinen, Kari Juntunen, Taija Leinonen, Alexandra Komander, Kim Langfelder, Jari Vehmaanpera, Terhi Puranen
  • Patent number: 9434972
    Abstract: The present invention relates to processes for processes for enzymatic refining of a pretreated cellulosic material for saccharification.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: September 6, 2016
    Assignee: Novozymes North America, Inc.
    Inventors: Armindo Ribiero Gaspar, Donald Higgins, Ye Chen, Hui Xu
  • Patent number: 9267144
    Abstract: A method is provided for transforming maize plants to express DNA sequences of interest from plant cell plastids. The method allows the transformation of maize plant tissue with heterologous DNA constructs by microprojectile bombardment of green light grown cultures and dark grown embryogenic cultures. The invention also provides for maize cells in which the plastids contain heterologous DNA constructs.
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: February 23, 2016
    Assignee: Monsanto Technology LLC
    Inventors: Vladimir Sidorov, Jeffrey M. Staub, Yuechun Wan, Guangning Ye
  • Patent number: 9260491
    Abstract: It is an object of the present invention to provide a protein that can successfully treats almost all patients with cedar pollinosis and can be ingested as a food. That is, the present invention provides a protein comprising an amino acid sequence represented by SEQ ID NO:1 or comprising an amino acid sequence having a mutation(s) in said amino acid sequence, and having an immunogenicity of a cedar pollen; a polynucleotide encoding said protein; a vector comprising said polynucleotide; a transformant comprising said polynucleotide or said vector; and intended uses of said protein, said polynucleotide, and said transformant.
    Type: Grant
    Filed: October 28, 2010
    Date of Patent: February 16, 2016
    Assignees: NIPPON PAPER INDUSTRIES CO., LTD., NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES
    Inventors: Fumio Takaiwa, Hidenori Takagi, Yuhya Wakasa, Yuji Fujii, Tomotaka Shinya, Saori Kasahara
  • Patent number: 9234187
    Abstract: Disclosed herein are compositions and method comprising non-canonical (e.g., non-C2H2) zinc finger proteins.
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: January 12, 2016
    Assignee: Sangamo BioSciences, Inc.
    Inventors: Edward Rebar, Andrew Jamieson
  • Patent number: 9187760
    Abstract: The present invention discloses pharmaceutical products useful for the treatment of allergies, autoimmune diseases, vaccination of mammals, as well as for in vitro diagnostics. These products preferably comprise pollen grains having altered protein composition by means of genetic modification in the plant that produces them. The production process of the present invention comprises the cultivation of genetically modified plants capable of producing pollen grains having modified molecular composition.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: November 17, 2015
    Assignee: Ricardo Amaral Remer
    Inventors: Ricardo Amaral Remer, Rogerio Margis, Marcio Alves Ferreira, Marcia Coronha Lima
  • Patent number: 9181310
    Abstract: The present invention provides compositions and methods for killing or suppressing growth of Gram-negative bacteria that infect, infest or cause disease in plants, including pathogenic, saprophytic and opportunistic microbes that cause disease in plants and food borne illness in people or in animal feed.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: November 10, 2015
    Assignees: University of Florida Research Foundation, Inc., Integrated Plant Genetics, Inc.
    Inventors: Dean W. Gabriel, Yingnan Jiang
  • Patent number: 9175276
    Abstract: The present invention relates to isolated polypeptides having endoglucanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: February 12, 2013
    Date of Patent: November 3, 2015
    Assignee: Novozymes, Inc.
    Inventor: Nikolaj Spodsberg
  • Patent number: 9169488
    Abstract: An object of the present invention is to search for a gene having a novel function that can cause an increase or decrease in material productivity, and particularly, fat and oil content. In the present invention, a chimeric protein obtained by fusing a transcription factor consisting of a protein comprising an amino acid sequence shown in any of the even-numbered SEQ ID NOS: 1 to 158 and a functional peptide capable of converting an arbitrary transcription factor into a transcriptional repressor is expressed in a plant.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: October 27, 2015
    Assignee: TOYOTA JIDOSHA KABUSHIKI KAISHA
    Inventors: Satoshi Kondo, Chikara Ohto, Nobuhiko Muramoto, Norihiro Mitsukawa, Masaru Takagi, Kyoko Matsui
  • Patent number: 9163254
    Abstract: An object of the present invention is to identify sequence features of the 5? UTR, which are involved in changes in the translational state of plants under environmental stresses, and to provide a recombinant DNA molecule, an expression vector, a transformant, and the like, having the above sequence features.
    Type: Grant
    Filed: August 19, 2010
    Date of Patent: October 20, 2015
    Assignee: National University Corporation Nara Institute of Science and Technology
    Inventors: Ko Kato, Shigehiko Kanaya, Hideyuki Matsuura, Shinya Takenami, Tatsuya Nosho, Yuhki Kubo, Kiyotaka Ueda
  • Patent number: 9150873
    Abstract: The present invention relates to plant cells and plants which synthesize an increased amount of glucosaminoglycans, and to methods for preparing such plants, and also to methods for preparing glucosaminoglycans with the aid of these plant cells or plants. Here, plant cells or genetically modified plants according to the invention have glucosaminoglycan synthase activity and additionally an increased glucosamine 6-phosphate acetyltransferase activity and an increased UDP-N-acetyl-glucosamine pyrophosphorylase activity compared to wild-type plant cells or wild-type plants. The present invention furthermore relates to compositions comprising plant cells having an increased glucosaminoglycan synthesis.
    Type: Grant
    Filed: September 11, 2008
    Date of Patent: October 6, 2015
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Claus Frohberg, Bernd Essigmann
  • Patent number: 9145565
    Abstract: The present invention provides for a method or methods of targeted genetic recombination or mutagenesis in a host cell or organism, and compositions useful for carrying out the method. The targeting method of the present invention exploits endogenous cellular mechanisms for homologous recombination and repair of double stranded breaks in genetic material. The present invention provides numerous improvements over previous mutagenesis methods, such advantages include that the method is generally applicable to a wide variety of organisms, the method is targeted so that the disadvantages associated with random insertion of DNA into host genetic material are eliminated, and certain embodiments require relatively little manipulation of the host genetic material for success. Additionally, it provides a method that produces organisms with specific gene modifications in a short period of time.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: September 29, 2015
    Assignee: University of Utah Research Foundation
    Inventors: Dana Carroll, Mary M. Golic, Marina Bibikova, Gary Drews, Kent G. Golic
  • Patent number: 9127286
    Abstract: A method for increasing the amount of trans-1,4-polyisoprene contained in a plant, and a method for effectively producing trans-1,4-polyisoprene using a plant are provided. A long-chain trans-prenyl diphosphate synthase gene that comprises DNA having at least one base sequence selected from the group consisting of a base sequence from positions 88 to 1134 of the base sequence of SEQ ID NO: 1 or a complementary sequence thereof, a base sequence from positions 42 to 1088 of the base sequence of SEQ ID NO: 3 or a complementary sequence thereof, and a base sequence from positions 91 to 1140 of the base sequence of SEQ ID NO: 5 or a complementary sequence thereof are disclosed; as well as a plant transformed with an expression vector containing the gene.
    Type: Grant
    Filed: August 31, 2009
    Date of Patent: September 8, 2015
    Assignee: Hitachi Zosen Corporation
    Inventors: Yoshihisa Nakazawa, Yoko Harada, Hirotaka Uefuji, Ren Chen, Takeshi Bamba, Akio Kobayashi, Eiichiro Fukusaki, Kazumasa Hirata, Koichiro Gyokusen
  • Patent number: 9121028
    Abstract: This invention discloses methods for providing plants with selective expression of a target RNA and methods for evaluating an expression pattern of a target RNA in a plant. Also disclosed are transgenic plants having recombinant DNA for expressing a protein using a promoter functional in multiple tissues, and recombinant DNA for suppressing expression of the protein using a promoter functional in fewer than the multiple tissues.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: September 1, 2015
    Assignee: Monsanto Technology LLC
    Inventors: Paul S. Chomet, Michael D. Edgerton
  • Patent number: 9115366
    Abstract: The invention concerns a method for producing terpenes of interest in plants having glandular trichomes, as well as plants useful for producing said terpenes of interest. Said plants comprise a sequence encoding a heterologous terpene synthase under the control of a promoter enabling it to be specifically expressed in the trichomes. Moreover, the pathway for producing endogenous diterpenes is preferably blocked in the trichomes of the plants, to increase the flow in the heterologous pathway. The secretion of heterologous terpenes is spontaneous resulting in easy collection. The present invention also concerns plants exhibiting a blocked production of a compound having antibiotic properties at the surface of leaves exhibiting enhanced efficiency of transformation by a bacterium.
    Type: Grant
    Filed: January 27, 2006
    Date of Patent: August 25, 2015
    Assignee: PHILIP MORRIS PRODUCTS S.A.
    Inventors: Alain Tissier, Christophe Sallaud, Denis Rontein
  • Patent number: 9085774
    Abstract: The present invention is in the field of genetics, especially plant genetics, and provides agents capable of controlling gene expression. The present invention specifically provides sequences of naturally occurring, tissue-specifically expressed microRNAs. The invention further provides for transgenic expression constructs comprising sequences encoding said microRNAs. By incorporation of the microRNA encoding sequence the expression from said expression construct is specifically silenced in the tissue where the naturally occurring microRNA is naturally expressed. Thereby the expression profile resulting from the promoter is modulated and leakiness is reduced. The invention further provides for a method for modulating transgenic expression by incorporating sequences encoding said microRNAs into transgenic expression constructs.
    Type: Grant
    Filed: April 13, 2006
    Date of Patent: July 21, 2015
    Assignee: BASF Plant Science GmbH
    Inventors: Peifeng Ren, Hee-Sook Song, John McMillan
  • Patent number: 9068191
    Abstract: This invention provides methods of transiently expressing a nucleotide sequence in one or more cells of a soybean plant, comprising: a) abrading the surface of a soybean plant and/or intact part thereof; and either (b1) immersing the abraded plant and/or abraded intact part thereof in a solution comprising Agrobacterium cells and a surfactant, wherein the Agrobacterium cells comprise the nucleotide sequence to be transiently expressed; (b2) applying a vacuum to the immersed soybean plant and/or intact part thereof of step (b1); and (b3) releasing the vacuum, thereby introducing the solution into the plant and/or intact part thereof; or (c) contacting the abraded plant and/or abraded intact part thereof with a solution comprising Agrobacterium cells and a surfactant, wherein the Agrobacterium cells comprise the nucleotide sequence to be transiently expressed, whereby the nucleotide sequence is transiently expressed in one or more cells of the plant.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: June 30, 2015
    Assignee: Syngenta Participations AG
    Inventors: Kasimalai Azhakanandam, Pei Su