Method Of Introducing A Polynucleotide Molecule Into Or Rearrangement Of Genetic Material Within A Plant Or Plant Part Patents (Class 800/278)
  • Patent number: 12043837
    Abstract: This document relates to methods and materials for genome engineering in eukaryotic cells, and particularly to methods for increasing genome engineering (i.e. transformation or genome editing) efficiency via delivery of one or more booster polypeptides, and boost genes, with genome engineering components.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: July 23, 2024
    Assignee: KWS SAAT SE & Co. KGaA
    Inventor: Ling Meng
  • Patent number: 12041904
    Abstract: A novel soybean variety, designated 5PRAD49 is provided. Also provided are the seeds of soybean variety 5PRAD49, cells from soybean variety 5PRAD49, plants of soybean 5PRAD49, and plant parts of soybean variety 5PRAD49. Methods provided include producing a soybean plant by crossing soybean variety 5PRAD49 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PRAD49, methods for producing other soybean varieties or plant parts derived from soybean variety 5PRAD49, and methods of characterizing soybean variety 5PRAD49. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PRAD49 are further provided.
    Type: Grant
    Filed: February 3, 2022
    Date of Patent: July 23, 2024
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Andrea Beth Kalvig, Leslie Charles Kuhlman, Donald Kyle
  • Patent number: 12043838
    Abstract: Systems, methods, and compositions for providing improvements in plant gene-editing efficiency are provided.
    Type: Grant
    Filed: March 6, 2023
    Date of Patent: July 23, 2024
    Assignee: INARI AGRICULTURE TECHNOLOGY, INC.
    Inventors: Hannah Pham, Yajie Niu, Erik William Clement
  • Patent number: 12029193
    Abstract: The invention provides seeds and plants of pepper hybrid SVPB7456. The invention thus relates to the plants, seeds, plant parts, and tissue cultures of pepper hybrid SVPB7456 and to methods for producing a pepper plant produced by crossing such plants with themselves or with another plant, such as a pepper plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to plants, seeds, plant parts, and tissue cultures of pepper hybrid SVPB7456, comprising introduced beneficial or desirable traits.
    Type: Grant
    Filed: June 19, 2023
    Date of Patent: July 9, 2024
    Assignee: SEMINIS VEGETABLE SEEDS, INC.
    Inventor: William McCarthy
  • Patent number: 12022787
    Abstract: Disclosed herein are methods for sterile extraction, drying, storage, and transformation of immature and mature maize and monocot embryos. The present disclosure also describes a dried, storable, freezable value added maize and monocot explants.
    Type: Grant
    Filed: June 18, 2020
    Date of Patent: July 2, 2024
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Brian Joseph Martinell, Michael William Petersen, Edward James Williams, Frank Lloyd McFarland, Nathaniel Schleif, Shawn Michael Kaeppler, Heidi Flewelling Kaeppler
  • Patent number: 12022791
    Abstract: A novel soybean variety, designated 5PKLQ07 is provided. Also provided are the seeds of soybean variety 5PKLQ07, cells from soybean variety 5PKLQ07, plants of soybean 5PKLQ07, and plant parts of soybean variety 5PKLQ07. Methods provided include producing a soybean plant by crossing soybean variety 5PKLQ07 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PKLQ07, methods for producing other soybean varieties or plant parts derived from soybean variety 5PKLQ07, and methods of characterizing soybean variety 5PKLQ07. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PKLQ07 are further provided.
    Type: Grant
    Filed: October 8, 2021
    Date of Patent: July 2, 2024
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventor: Nadia Nikolayevna Krasheninnik
  • Patent number: 12022792
    Abstract: A novel soybean variety, designated 5PJWM85 is provided. Also provided are the seeds of soybean variety 5PJWM85, cells from soybean variety 5PJWM85, plants of soybean 5PJWM85, and plant parts of soybean variety 5PJWM85. Methods provided include producing a soybean plant by crossing soybean variety 5PJWM85 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PJWM85, methods for producing other soybean varieties or plant parts derived from soybean variety 5PJWM85, and methods of characterizing soybean variety 5PJWM85. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PJWM85 are further provided.
    Type: Grant
    Filed: October 8, 2021
    Date of Patent: July 2, 2024
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Kyle James Kocak, Landon Linn Ries
  • Patent number: 12016299
    Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011203. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011203, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011203 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011203.
    Type: Grant
    Filed: November 17, 2021
    Date of Patent: June 25, 2024
    Assignee: Monsanto Technology LLC
    Inventors: Christian J. Buffard, Jeffrey M. Sernett, Gary R. Stangland
  • Patent number: 12016356
    Abstract: Newly identified fungal sweet-taste modifying proteins, and the cDNA encoding said proteins are described. Specifically, Myd proteins active in sweet taste activation, and the cDNA encoding the same, are described, along with methods for isolating such cDNA and for isolating and expressing such proteins. Also disclosed is use of a sweetening composition which includes the proteins of the invention, and methods to provide improved flavor to a product for oral administration.
    Type: Grant
    Filed: February 25, 2022
    Date of Patent: June 25, 2024
    Assignee: MYCOTECNOLOGY, INC.
    Inventors: Marina Nadal, Anthony J. Clark, Zheyuan Guo, Stephen A. Gravina, Anthony Westgate, Bassam Alkotaini, Ashley Han, Brendan Sharkey, Evan Strassburger, Joseph Meilen, Hyung Chang, Alan D. Hahn
  • Patent number: 12010973
    Abstract: The invention provides seeds and plants of pepper line SMO-E718-0956. The invention thus relates to the plants, seeds, plant parts, and tissue cultures of pepper line SMO-E718-0956 and to methods for producing a pepper plant produced by crossing such plants with themselves or with another plant, such as a pepper plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to plants, seeds, plant parts, and tissue cultures of pepper line SMO-E718-0956 comprising introduced beneficial or desirable traits.
    Type: Grant
    Filed: March 30, 2023
    Date of Patent: June 18, 2024
    Assignee: SEMINIS VEGETABLE SEEDS, INC.
    Inventor: William McCarthy
  • Patent number: 12012607
    Abstract: Materials and methods are provided for making plants (e.g., Triticum varieties) with increased levels of dietary fiber, such as by making TALE nuclease-induced mutations in alleles encoding starch branching enzyme IIa (SBEIIa) and starch branching enzyme IIb (SBEIIb).
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: June 18, 2024
    Assignee: Cellectis
    Inventors: Nicholas Baltes, Javier Gil Humanes
  • Patent number: 12010964
    Abstract: The invention provides seeds and plants of cucumber inbred line API-M317-0802GY. The invention thus relates to the plants, seeds, plant parts, and tissue cultures of cucumber inbred line API-M317-0802GY and to methods for producing a cucumber plant produced by crossing such plants with themselves or with another plant, such as a cucumber plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to plants, seeds, plant parts, and tissue cultures of cucumber inbred line API-M317-0802GY comprising introduced beneficial or desirable traits.
    Type: Grant
    Filed: March 10, 2022
    Date of Patent: June 18, 2024
    Assignee: SEMINIS VEGETABLE SEEDS, INC.
    Inventor: Nischit Shetty
  • Patent number: 12004467
    Abstract: According to the invention, there is provided seed and plants of the corn variety designated CV399111. The invention thus relates to the plants, seeds and tissue cultures of the variety CV399111, and to methods for producing a corn plant produced by crossing a corn plant of variety CV399111 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV399111 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV399111.
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: June 11, 2024
    Assignee: Monsanto Technology LLC
    Inventors: Marvin L. Boerboom, Todd Frank, Zachary King
  • Patent number: 12004471
    Abstract: According to the invention, there is provided seed and plants of the corn variety designated CV525601. The invention thus relates to the plants, seeds and tissue cultures of the variety CV525601, and to methods for producing a corn plant produced by crossing a corn plant of variety CV525601 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV525601 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV525601.
    Type: Grant
    Filed: November 22, 2021
    Date of Patent: June 11, 2024
    Assignee: Monsanto Technology LLC
    Inventor: Jorge Moran
  • Patent number: 11997973
    Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011190. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011190, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011190 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011190.
    Type: Grant
    Filed: November 17, 2021
    Date of Patent: June 4, 2024
    Assignee: Monsanto Technology LLC
    Inventors: Sandeep Bhatnagar, Gregory J. Holland, Gary R. Stangland, Clinton J. Turnbull
  • Patent number: 11997969
    Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011160. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011160, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011160 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011160.
    Type: Grant
    Filed: October 26, 2021
    Date of Patent: June 4, 2024
    Assignee: Monsanto Technology LLC
    Inventors: Fufa H. Birru, Christian J. Buffard, Jeffrey M. Sernett
  • Patent number: 11997974
    Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011200. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011200, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011200 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011200.
    Type: Grant
    Filed: November 17, 2021
    Date of Patent: June 4, 2024
    Assignee: Monsanto Technology LLC
    Inventors: Sandeep Bhatnagar, Gregory J. Holland, Gary R. Stangland, Clinton J. Turnbull
  • Patent number: 11997977
    Abstract: A novel soybean variety, designated 5PEUR38 is provided. Also provided are the seeds of soybean variety 5PEUR38, cells from soybean variety 5PEUR38, plants of soybean 5PEUR38, and plant parts of soybean variety 5PEUR38. Methods provided include producing a soybean plant by crossing soybean variety 5PEUR38 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PEUR38, methods for producing other soybean varieties or plant parts derived from soybean variety 5PEUR38, and methods of characterizing soybean variety 5PEUR38. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PEUR38 are further provided.
    Type: Grant
    Filed: October 11, 2021
    Date of Patent: June 4, 2024
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Reid Rolland Rice, Catlynn Gail Salois, Brian Frederick Seda, Charles Thomas Zila, III
  • Patent number: 11999982
    Abstract: A microorganism is transformed to be capable of producing guanidinoacetic acid (GAA). A method can be used for the fermentative production of GAA using such a microorganism. A corresponding method can be used for the fermentative production of creatine.
    Type: Grant
    Filed: June 28, 2021
    Date of Patent: June 4, 2024
    Assignee: Evonik Operations GmbH
    Inventors: Frank Schneider, Frank Jankowitsch
  • Patent number: 11985942
    Abstract: According to the invention, there is provided seed and plants of the corn variety designated CV495012. The invention thus relates to the plants, seeds and tissue cultures of the variety CV495012, and to methods for producing a corn plant produced by crossing a corn plant of variety CV495012 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV495012 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV495012.
    Type: Grant
    Filed: November 4, 2021
    Date of Patent: May 21, 2024
    Assignee: Monsanto Technology LLC
    Inventor: Donald L. Bockelman
  • Patent number: 11980159
    Abstract: A new and distinct tomato variety NUN 09282 TOF is disclosed, as well as seeds and plants and fruits thereof. NUN 09282 TOF is an indeterminate intense tomato variety for the fresh market, comprising resistance to Verticillium dahliae Race 0, Fusarium oxysporum f sp. lycopersici Races 0 and 1, Fusarium oxysporum f sp. radicis lycopersici, Fulvia fulva Groups A-E, and Tomato Mosaic Virus (ToMV) Strains 0, 1, 2, and 1-2.
    Type: Grant
    Filed: December 10, 2021
    Date of Patent: May 14, 2024
    Assignee: NUNHEMS B.V.
    Inventor: Ben Silvertand
  • Patent number: 11981900
    Abstract: This disclosure provides methods and compositions for increasing genome editing and site-directed integration events utilizing guided endonucleases and meiotic cell-preferred, egg cell-preferred or embryo tissue-preferred promoters.
    Type: Grant
    Filed: September 9, 2021
    Date of Patent: May 14, 2024
    Assignee: Monsanto Technology LLC
    Inventors: Matthew J. Bauer, Lisa Kanizay, Jonathan Lamb, Matthew S. Marengo, Brent O'Brien
  • Patent number: 11976285
    Abstract: Provided herein are KRN2 gene controlling kernel row number in plant, molecular markers closely linked to KRN2 and their application in molecular breeding.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: May 7, 2024
    Assignee: CHINA AGRICULTURAL UNIVERSITY
    Inventors: Xiaohong Yang, Jiansheng Li, Wenkang Chen, Xuan Zhang, Lichun Cai, Yirong Zhang
  • Patent number: 11976289
    Abstract: Isolated polynucleotides and polypeptides, and recombinant DNA constructs are useful for conferring improved drought tolerance and yield. Compositions (such as plants or seeds) comprise these recombinant DNA constructs; and methods utilize these recombinant DNA constructs. The recombinant DNA constructs comprise a polynucleotide operably linked to a promoter that is functional in a plant, wherein said polynucleotides encode drought tolerance polypeptides.
    Type: Grant
    Filed: May 22, 2019
    Date of Patent: May 7, 2024
    Inventors: Guihua Lu, Guokui Wang, Guanfan Mao, Yu Zhang, Changgui Wang, Guangwu Chen, Yang Gao
  • Patent number: 11976288
    Abstract: Isolated polynucleotides and polypeptides, and recombinant DNA constructs are useful for conferring improved nitrogen stress tolerance or NUE and yield. Compositions (such as plants or seeds) comprise these recombinant DNA constructs; and methods utilize these recombinant DNA constructs. The recombinant DNA constructs comprise a polynucleotide operably linked to a promoter that is functional in a plant, wherein said polynucleotides encode nitrogen stress tolerance polypeptides.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: May 7, 2024
    Inventors: Guihua Lu, Guokui Wang, Guanfan Mao, Rongrong Jiao, Yu Zhang, Changgui Wang, Jiantao Wang, Yang Gao
  • Patent number: 11968940
    Abstract: A novel maize variety designated 8SSIX6027 and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety 8SSIX6027 with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into 8SSIX6027 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety 8SSIX6027 or a locus conversion of 8SSIX6027 with another maize variety.
    Type: Grant
    Filed: October 25, 2021
    Date of Patent: April 30, 2024
    Assignee: AGRIGENETICS, INC.
    Inventors: Stephen Baluch, Michael B Letchworth, Jenelle D F Meyer, Samuel A Ordonez, Jr.
  • Patent number: 11970703
    Abstract: The present invention relates to a safflower plant or part thereof involving the molecular stacking of safflower events IND-1ØØØ3-4 x IND-1ØØ15-7, wherein the plant produces and accumulates chymosin in seed under agricultural conditions. A plant seed involving the molecular stacking of safflower events IND-1ØØØ3-4 x IND-1ØØ15-7. A consumer product produced from the seed, defined as chymosin, and additionally as ground grain, flour, flakes, oil, biodiesel, biogas, or another biomaterial. Also, the present invention include a recombinant DNA molecule involved in the molecular stacking of safflower events IND-1ØØØ3-4 x IND-1ØØ15-7. A DNA polynucleotide primer molecule comprising at least 15 contiguous nucleotides of the DNA molecule involved in the molecular stacking of safflower events IND-1ØØØ3-4 x IND-1ØØ15-7, or its complement which is useful in a DNA amplification method to produce a diagnostic amplicon for the event IND-1ØØØ3-4 and IND-1ØØ15-7, or each of them separately IND-1ØØØ3-4 and IND-1ØØ15-7.
    Type: Grant
    Filed: September 20, 2022
    Date of Patent: April 30, 2024
    Assignee: AG BIOMOLECULES LLC
    Inventors: Mariana Chiozza, Carlos Dezar, Patricia Miranda, Lucas Paultroni, Martin Salinas
  • Patent number: 11968948
    Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011220. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011220, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011220 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011220.
    Type: Grant
    Filed: November 18, 2021
    Date of Patent: April 30, 2024
    Assignee: Monsanto Technology LLC
    Inventors: Gregory J. Holland, Jeffrey M. Sernett, Gary R. Stangland, Clinton J. Turnbull
  • Patent number: 11963507
    Abstract: A novel soybean variety, designated 5PJWA71 is provided. Also provided are the seeds of soybean variety 5PJWA71, cells from soybean variety 5PJWA71, plants of soybean 5PJWA71, and plant parts of soybean variety 5PJWA71. Methods provided include producing a soybean plant by crossing soybean variety 5PJWA71 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PJWA71, methods for producing other soybean varieties or plant parts derived from soybean variety 5PJWA71, and methods of characterizing soybean variety 5PJWA71. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PJWA71 are further provided.
    Type: Grant
    Filed: October 8, 2021
    Date of Patent: April 23, 2024
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventor: Zachary Phillip Shearin
  • Patent number: 11963504
    Abstract: According to the invention, there is provided seed and plants of the corn variety designated CV516589. The invention thus relates to the plants, seeds and tissue cultures of the variety CV516589, and to methods for producing a corn plant produced by crossing a corn plant of variety CV516589 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV516589 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV516589.
    Type: Grant
    Filed: November 18, 2021
    Date of Patent: April 23, 2024
    Assignee: Monsanto Technology LLC
    Inventor: Devin Michael Nichols
  • Patent number: 11965182
    Abstract: Transgenic plants having enhanced yield and having enhanced seed yield are disclosed. The transgenic plants are transformed with a transgenic polynucleotide encoding one or more metabolic enzymes. The metabolic enzymes can be from any biological source. The transgenic polynucleotide(s) comprises a nucleic acid sequences encoding the metabolic enzymes under the control of functional plant promoters, the one or more metabolic enzymes are targeted to the plastids by the addition of plastid targeting signals. Optionally the functional plant promoters are seed specific promoters and the metabolic enzymes are targeted to the plastids by the addition of plastid targeting peptide heterologous to the metabolic enzymes. Methods of making the transgenic plants and transgenic polynucleotides are disclosed. The magnitude of the increases in seed yield achieved with these transgenic plants are unprecedented.
    Type: Grant
    Filed: October 11, 2021
    Date of Patent: April 23, 2024
    Assignee: YIELD10 BIOSCIENCE, INC.
    Inventors: Meghna Malik, Jihong Tang, Kristi D. Snell
  • Patent number: 11965168
    Abstract: Soybean plants producing soybean seeds comprising leghemoglobin are produced by modifying the genome of the soybean plant. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin are provided. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin and additionally one or more of high oleic acid, low linolenic acid, high protein, low stachyose, low raffinose and low protease inhibitors are provided. Protein compositions comprising leghemoglobin, such as soy isolates and concentrates can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions comprising leghemoglobin are disclosed.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: April 23, 2024
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Hyeon-Je Cho, John D Everard, Anthony J Kinney, Zhan-Bin Liu, Knut Meyer, Thomas G Patterson, Kevin G Ripp, Bo Shen
  • Patent number: 11957101
    Abstract: A novel soybean variety, designated 5PVZL16 is provided. Also provided are the seeds of soybean variety 5PVZL16, cells from soybean variety 5PVZL16, plants of soybean 5PVZL16, and plant parts of soybean variety 5PVZL16. Methods provided include producing a soybean plant by crossing soybean variety 5PVZL16 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PVZL16, methods for producing other soybean varieties or plant parts derived from soybean variety 5PVZL16, and methods of characterizing soybean variety 5PVZL16. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PVZL16 are further provided.
    Type: Grant
    Filed: October 8, 2021
    Date of Patent: April 16, 2024
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Brian Allen Carden, Donald Kyle, Brian Frederick Seda
  • Patent number: 11951171
    Abstract: The present invention “A polypeptide EXP and its drug delivery system as well as extracellular vesicle extraction kit thereof” belongs to the field of biomedical engineering and diagnostics. The amino acid sequence of the polypeptide EXP is set forth in SEQ ID NO. 1. Based on the polypeptide EXP, the present invention also provides a drug delivery system, targeted drug delivery system, enhanced drug delivery vehicle, a drug with enhanced delivery, targeted drug, extracellular vesicle extraction kit, disease diagnostic kit, a method for purifying extracellular vesicles, and use of the polypeptide EXP in pharmacy and diagnostic reagent manufacture.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: April 9, 2024
    Assignee: TIANJIN MEDICAL UNIVERSITY
    Inventors: Haifang Yin, Ning Ran, Caorui Lin, Xianjun Gao
  • Patent number: 11950560
    Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011199. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011199, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011199 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011199.
    Type: Grant
    Filed: October 25, 2021
    Date of Patent: April 9, 2024
    Assignee: Monsanto Technology LLC
    Inventors: Fufa H. Birru, Christian J. Buffard, Jeffrey M. Sernett
  • Patent number: 11952583
    Abstract: The invention relates to lettuce plants comprising in its genome a mutant homoserine kinase allele in homozygous form, whereby the plants are resistant against Bremia lactucae.
    Type: Grant
    Filed: September 19, 2019
    Date of Patent: April 9, 2024
    Assignee: Nunhems B.V.
    Inventor: Wim Vriezen
  • Patent number: 11952579
    Abstract: A recombinant DNA construct is disclosed. When the recombinant DNA construct is expressed in a plant or a plant cell, endogenous HD-Zip class II proteins become less able to repress DNA transcription of the genes they typically regulate. The recombinant DNA construct can be expressed in plant cells to produce plants with enhanced phenotypes. Methods of making transgenic plants comprising the recombinant DNA construct, and plants produced thereby are also disclosed.
    Type: Grant
    Filed: October 15, 2020
    Date of Patent: April 9, 2024
    Assignee: Monsanto Technology LLC
    Inventors: Cara L. Griffith, Abha Khandelwal, Paul J. Loida, Elena A. Rice, Rebecca L. Thompson, Sivalinganna Manjunath
  • Patent number: 11950556
    Abstract: A novel maize variety designated X03R591 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X03R591 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X03R591 through backcrossing or genetic transformation, and to the maize seed, plant and plant part produced thereby are described. Maize variety X03R591, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X03R591 are provided. Methods for producing maize varieties derived from maize variety X03R591 and methods of using maize variety X03R591 are disclosed.
    Type: Grant
    Filed: October 20, 2021
    Date of Patent: April 9, 2024
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventor: Michael Adam Chandler
  • Patent number: 11946061
    Abstract: The invention relates to novel methods and compositions for conferring tolerance to glyphosate to plants. The invention also provides glyphosate-tolerant plants, seeds, tissue, cells, and plant parts comprising modified EPSP synthases and recombinant DNA molecules encoding modified EPSP synthases, as well as methods of producing the same and the use thereof.
    Type: Grant
    Filed: August 19, 2022
    Date of Patent: April 2, 2024
    Assignee: Monsanto Technology LLC
    Inventors: Guillermo A. Asmar-Rovira, Stephen M. Duff, Shirley X. Guo, Jingdong Liu, R. Douglas Sammons, Lei Shi
  • Patent number: 11944059
    Abstract: According to the invention, there is provided seed and plants of the corn variety designated CV399333. The invention thus relates to the plants, seeds and tissue cultures of the variety CV399333, and to methods for producing a corn plant produced by crossing a corn plant of variety CV399333 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV399333 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV399333.
    Type: Grant
    Filed: October 21, 2021
    Date of Patent: April 2, 2024
    Assignee: Monsanto Technology LLC
    Inventors: Marvin L. Boerboom, Todd Frank, Zachary King
  • Patent number: 11930770
    Abstract: The invention relates to the soybean variety designated 01091765. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01091765. Also provided by the invention are tissue cultures of the soybean variety 01091765 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01091765 with itself or another soybean variety and plants produced by such methods.
    Type: Grant
    Filed: October 1, 2021
    Date of Patent: March 19, 2024
    Assignee: Monsanto Technology LLC
    Inventors: James Behm, Thomas L. Floyd
  • Patent number: 11917965
    Abstract: According to the invention, there is provided seed and plants of the corn variety designated CV397329. The invention thus relates to the plants, seeds and tissue cultures of the variety CV397329, and to methods for producing a corn plant produced by crossing a corn plant of variety CV397329 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV397329 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV397329.
    Type: Grant
    Filed: October 20, 2021
    Date of Patent: March 5, 2024
    Assignee: Monsanto Technology LLC
    Inventor: Jon Popi
  • Patent number: 11917962
    Abstract: The disclosure relates to cucumber plants producing fruits comprising a small seed cavity and/or an increased dry matter content, and to methods for generating such plants, and their use.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: March 5, 2024
    Assignee: Nunhems B.V.
    Inventor: Robert Swinkels
  • Patent number: 11917964
    Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011163. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011163, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011163 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011163.
    Type: Grant
    Filed: October 15, 2021
    Date of Patent: March 5, 2024
    Assignee: Monsanto Technology LLC
    Inventor: Nathaniel J. Page
  • Patent number: 11917967
    Abstract: A soybean cultivar designated 4826005 is disclosed. Embodiments include the seeds of soybean 4826005, the plants of soybean 4826005, to plant parts of soybean 4826005, and methods for producing a soybean plant produced by crossing soybean 4826005 with itself or with another soybean variety. Embodiments include methods for producing a soybean plant containing in its genetic material one or more genes or transgenes and the transgenic soybean plants and plant parts produced by those methods. Embodiments also relate to soybean cultivars, breeding cultivars, plant parts, and cells derived from soybean 4826005, methods for producing other soybean cultivars, lines or plant parts derived from soybean 4826005, and the soybean plants, varieties, and their parts derived from use of those methods. Embodiments further include hybrid soybean seeds, plants, and plant parts produced by crossing 4826005 with another soybean cultivar.
    Type: Grant
    Filed: June 15, 2021
    Date of Patent: March 5, 2024
    Assignee: Benson Hill Seeds, Inc.
    Inventor: Pedro Gonzalez-Portilla
  • Patent number: 11917975
    Abstract: A soybean cultivar designated 05410624 is disclosed. The invention relates to the seeds of soybean cultivar 05410624, to the plants of soybean cultivar 05410624, to the plant parts of soybean cultivar 05410624, and to methods for producing progeny of soybean cultivar 05410624. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 05410624. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 05410624, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 05410624 with another soybean cultivar.
    Type: Grant
    Filed: October 7, 2021
    Date of Patent: March 5, 2024
    Assignee: M.S. Technologies, L.L.C.
    Inventor: Justin T. Mason
  • Patent number: 11913034
    Abstract: The present invention relates a polypeptide having kaurenoic acid 13-hydroxylase activity, which polypeptide comprises an amino acid sequence which, when aligned with a kaurenoic acid 13-hydroxylase comprising the sequence set out in SEQ ID NO: 1 or SEQ ID NO: 3, comprises at least one substitution of an amino acid corresponding to any of amino acids at positions 136, 248, 336 or 403, said positions being defined with reference to SEQ ID NO: 1 or SEQ ID NO: 3 and wherein the polypeptide has one or more modified properties as compared with a reference polypeptide having kaurenoic acid 13-hydroxylase activity. A polypeptide of the invention may be used in a recombinant host for the production of steviol or a steviol glycoside.
    Type: Grant
    Filed: July 21, 2021
    Date of Patent: February 27, 2024
    Assignee: DSM IP ASSETS B.V.
    Inventors: Johannes Gustaaf Ernst Van Leeuwen, Priscilla Zwartjens, Viktor Marius Boer
  • Patent number: 11910775
    Abstract: A novel maize variety designated 7SSMM2111 and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety 7SSMM2111 with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into 7SSMM2111 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety 7SSMM2111 or a locus conversion of 7SSMM2111 with another maize variety.
    Type: Grant
    Filed: October 21, 2021
    Date of Patent: February 27, 2024
    Assignee: AGRIGENETICS, INC.
    Inventor: Michael B Letchworth
  • Patent number: 11913003
    Abstract: The present invention relates to a method of improving soybean transformation efficiency, which comprises: transforming a plant cell using a recombinant vector containing a gene of interest and a gene encoding a sulfonylurea herbicide hydrolase; screening and culturing the transformed plant cell by external application of an ALS inhibitor, using the gene encoding the sulfonylurea herbicide hydrolase as a selective marker; selecting a plant cell that has not been killed and/or not been inhibited.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: February 27, 2024
    Assignee: BEIJING DABEINONG BIOTECHNOLOGY CO., LTD.
    Inventors: Yanhua Liu, Yuanyuan Wang, Zhiwei Jia, Qingfang Song
  • Patent number: 11895979
    Abstract: A soybean cultivar designated 04420512 is disclosed. The invention relates to the seeds of soybean cultivar 04420512, to the plants of soybean cultivar 04420512, to the plant parts of soybean cultivar 04420512, and to methods for producing progeny of soybean cultivar 04420512. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 04420512. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 04420512, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 04420512 with another soybean cultivar.
    Type: Grant
    Filed: November 1, 2021
    Date of Patent: February 13, 2024
    Assignee: M.S. Technologies, L.L.C.
    Inventor: Justin T. Mason