Method Of Introducing A Polynucleotide Molecule Into Or Rearrangement Of Genetic Material Within A Plant Or Plant Part Patents (Class 800/278)
  • Patent number: 11225669
    Abstract: The invention provides recombinant DNA molecules comprising novel synthetic Intergenic Sequence Regions for use in plants to reduce the interaction of a first transgene expression cassette on a second transgene cassette when inserted between the first transgene cassette and second transgene cassette. The invention also provides transgenic plants, plant cells, plant parts, and seeds comprising the novel synthetic Intergenic Sequence Regions. The invention also provides methods to reduce the interaction between transgene expression cassettes using the novel synthetic Intergenic Sequence Regions.
    Type: Grant
    Filed: July 6, 2020
    Date of Patent: January 18, 2022
    Assignee: Monsanto Technology LLC
    Inventor: Ian W. Davis
  • Patent number: 11220694
    Abstract: The invention relates to novel plants, seeds and compositions, as well as improvements to plant breeding and methods for creating modifications in plant genomes.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: January 11, 2022
    Assignee: Inari Agriculture, Inc.
    Inventors: Tomá{hacek over (s)} {hacek over (C)}ermák, Richard Bailey Flavell, Eva Konecna, Yajie Niu, Michael Lee Nuccio, Jennifer A. Raji, Randall William Shultz, Davide Sosso, Maria Margarita D. Unson, Barry Andrew Martin, John Patrick Casey, Jr., Michael Andreas Kock
  • Patent number: 11180772
    Abstract: The present invention relates to a method of increasing resistance against fungal pathogens of the order Pucciniales, preferably the family Phacopsoraceae, in plants and/or plant cells. This is achieved by increasing the expression of an RLK2 protein or fragment thereof in a plant, plant part and/or plant cell in comparison to wild type plants, wild type plant parts and/or wild type plant cells. Furthermore, the invention relates to transgenic plants, plant parts, and/or plant cells having an increased resistance against fungal pathogens, in particular, pathogens of the order Pucciniales, preferably the family Phacopsoraceae, and to recombinant expression vectors comprising a sequence that is identical or homologous to a sequence encoding an RLK2 protein.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: November 23, 2021
    Assignee: BASF PLANT SCIENCE COMPANY GMBH
    Inventors: Holger Schultheiss, Tobias Mentzel, Ralf Flachmann
  • Patent number: 11178832
    Abstract: The present invention relates to crop breeding. More particularly, the present invention relates to targeted modification of root angle to enhance abiotic stress tolerance in maize. In one aspect, the invention provides recombinant maize exhibiting increased root angle by decreasing the function of the maize ZMCIPK15 gene. Methods of making the recombinant maize and various methods of plant selection and breeding are further provided.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: November 23, 2021
    Assignees: WISCONSIN ALUMNI RESEARCH FOUNDATION, THE PENN STATE RESEARCH FOUNDATION
    Inventors: Shawn Michael Kaeppler, Hannah Marie Schneider, Jonathan Paul Lynch, Malcolm John Bennett
  • Patent number: 11174491
    Abstract: Methods and materials for modulating low light and/or shade tolerance, and red light specific responses in plants are disclosed. For example, nucleic acids encoding low light and/or SD+EODFR-tolerance polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased low light and/or SD+EODFR tolerance. In addition, methods and materials involved in increasing UV-B tolerance in plants and methods and materials involved in modulating biomass levels in plants are provided.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: November 16, 2021
    Assignee: Ceres, Inc.
    Inventors: Shing Kwok, Kenneth Bounds, Ryan Miller, Sam Harris, James Burns, Roger I. Pennell, Vijay Sharma, Michael F. Portereiko, Han-Suk Kim, Gerard Magpantay
  • Patent number: 11174467
    Abstract: Transgenic plants having enhanced yield and having enhanced seed yield are disclosed. The transgenic plants are transformed with a transgenic polynucleotide encoding one or more metabolic enzymes. The metabolic enzymes can be from any biological source. The transgenic polynucleotide(s) comprises a nucleic acid sequences encoding the metabolic enzymes under the control of functional plant promoters, the one or more metabolic enzymes are targeted to the plastids by the addition of plastid targeting signals. Optionally the functional plant promoters are seed specific promoters and the metabolic enzymes are targeted to the plastids by the addition of plastid targeting peptide heterologous to the metabolic enzymes. Methods of making the transgenic plants and transgenic polynucleotides are disclosed. The magnitude of the increases in seed yield achieved with these transgenic plants are simply unprecedented.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: November 16, 2021
    Assignee: YIELD10 BIOSCIENCE, INC.
    Inventors: Meghna Malik, Jihong Tang, Kristi D. Snell
  • Patent number: 11168036
    Abstract: The invention relates to compositions for retaining soil moisture and improving plant growth in dry soils, which, together with one or more moisture retaining materials and wetting agents, comprises iron(III) oxides and optionally potassium metabisulfite [borken (HU), E224] as potentiating agent. The iron(III) oxides preferably are microparticulate. The composition Suitably comprises iron(III)oxides and potassium metabisulfite as potentiating agent. Other aspects of the invention relate to binding the moisture content of soils, as well as compositions for use in enhancing the efficacy of Soil retaining compositions.
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: November 9, 2021
    Assignee: INVENTION CENTER KFT.
    Inventors: Antal Vattay, Rikárd Vattay, Katalin Andrea Posta, Péter Póti, Imre Varga, Gyula Záray, Miklós Lóczi, Gábor Miklós Szurop
  • Patent number: 11168332
    Abstract: The invention provides recombinant host organisms (e.g., plants) genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins (e.g., PPTase and/or ACoAS) that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms (e.g., to obtain PUFAs) as well as products obtained from such organisms (e.g., oil and/or seed).
    Type: Grant
    Filed: June 2, 2020
    Date of Patent: November 9, 2021
    Inventors: Terence A. Walsh, Daniel Gachotte, Ann Owens Merlo, Paul Gordon Roessler, James Metz, Scott Bevan, Jerry Kuner
  • Patent number: 11168334
    Abstract: Isolated polynucleotides and polypeptides, and recombinant DNA constructs, suppression DNA constructs and CRISPR/Cas9 DNA constructs are provided. Compositions (such as plants or seeds) with modified expression or activity of the isolated polypeptides are obtained by transforming the regenerable plant cell with a suppression DNA construct or CRISPR/Cas construct. The plants with improving drought tolerance are obtained by decreasing the expression or activity of the isolated polynucleotide.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: November 9, 2021
    Inventors: Guangwu Chen, Chengfeng Du, Yang Gao, Zantang Li, Guihua Lu, Guanfan Mao, Changgui Wang, Guokui Wang
  • Patent number: 11149294
    Abstract: Described herein are biological devices and methods for using the same to produce carbo sugars. The biological devices include microbial cells transformed with a DNA construct containing genes for producing a cellulose synthase and galactomannan galactosyltransferase. In some instances, the biological devices also include a gene for lipase. Methods for altering the viscosity of petroleum oil using the carbo sugars are also described herein. Finally, methods for degreasing or decontaminating water mixed with petroleum oil or other fatty substances or a surface coated with petroleum oil or other fatty substances using the carbo sugars are described herein.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: October 19, 2021
    Assignee: BIOCAPITAL HOLDINGS, LLC
    Inventors: Raul Cuero Rengifo, Juliana Londoño Murillo, Mariana Sanchez Londoño, Daniel Agudelo Valencia, Juan Miguel Sanchez Bustamante, Mario Antonio Franco Jimenez, Lina Clemencia Sanchez Bustamante
  • Patent number: 11142765
    Abstract: The present disclosure relates to RNA interference (RNAi) reagents, such as short hairpin microRNA (shmiR) and short hairpin RNA (shRNA), for treatment of oculopharyngeal muscular dystrophy (OPMD), compositions comprising same, and use thereof to treat individuals suffering from OPMD or which are predisposed thereto. The present disclosure also relates to the use of the RNAi reagents in combination with PABPN1 replacement reagents, such as constructs which encode functional PABPN1 protein, for treatment of OPMD, compositions comprising same, and use thereof to treat individuals suffering from OPMD or which are predisposed thereto.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: October 12, 2021
    Assignee: Benitec IP Holdings, Inc.
    Inventors: Vanessa Strings-Ufombah, David Suhy
  • Patent number: 11136559
    Abstract: The invention generally relates to engineered prephenate dehydrogenases and arogenate dehydrogenases and methods of using the same. More specifically, the invention relates in part to compositions including engineered prephenate dehydrogenases (PDH) polypeptides and engineered arogenate dehydrogenase (ADH) polypeptides with altered substrate preferences and tyrosine sensitivities and methods of using the same.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: October 5, 2021
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Hiroshi A. Maeda, Craig Albert Schenck
  • Patent number: 11136591
    Abstract: The invention generally relates to plant cells and plants modified to increase resistance to necrotrophs or drought and methods of selecting and using the same. More specifically, the invention relates in part to plant cells and/or plants modified to eliminate or reduce as compared to control plants cell the NADPH oxidase activity or expression of certain respiratory burst oxidase homolog (RBOH) proteins and methods of selecting for and using the same.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: October 5, 2021
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Ashish Ranjan, Mehdi Kabbage, Damon Smith
  • Patent number: 11136588
    Abstract: The present invention relates to method for preparing a plant from a protoplast comprising knocking-out or knocking-in one or more the endogenous gene of the protoplast, and the plant regenerated from a genome-modified protoplast prepared by the above method.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: October 5, 2021
    Assignees: INSTITUTE FOR BASIC SCIENCE, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, AICT
    Inventors: Jin Soo Kim, Jungeun Kim, Sunghwa Choe, Je Wook Woo, Soon Il Kwon
  • Patent number: 11130961
    Abstract: The invention provides a transgenic soybean event MON 87708 plant and plants, plant cells, seeds, plant parts, and commodity products derived from event MON 87708. The invention also provides polynucleotides specific for event MON 87708 and plants, plant cells, seeds, plant parts, and commodity products comprising polynucleotides specific for event MON 87708. The invention also provides methods related to event MON 87708.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: September 28, 2021
    Assignee: Monsanto Technology LLC
    Inventors: Ronald J. Brinker, Wen C. Burns, Paul C. C. Feng, Anju Gupta, Sio-Wai Hoi, Marianne Malven, Kunsheng Wu
  • Patent number: 11130957
    Abstract: Provided are isolated polynucleotides and nucleic acid constructs which comprise a nucleic acid sequence at least 80% identical to a nucleic acid sequence selected form the group consisting of SEQ ID NOs: 277, 1-276, 278-469 and 785-2397; and isolated polypeptides which comprise an amino acid sequence at least 80% homologous to an amino acid sequence selected from the group consisting of SEQ ID NOs: 482, 470-481, 483-784 and 2398-3818. Also provided are transgenic cells and plants expressing same and methods of using same for increasing nitrogen use efficiency, yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, and/or abiotic stress tolerance of a plant.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: September 28, 2021
    Assignee: Evogene Ltd.
    Inventors: David Panik, Basia Judith Vinocur, Hagai Karchi
  • Patent number: 11130956
    Abstract: The present invention relates to the fields of genetically modified Agrobacterium strains, vaccine adjuvants, and generally molecular biology and immunology. Provided herein are modified Agrobacterium strains that produce lipopolysaccharide (LPS) having reduced toxicity or detoxified lipopolysaccharide, and methods of obtaining such strains for plant-based production of biologies. Also provided herein are uses of reduced or detoxified LPS as adjuvants suitable for clinical use.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: September 28, 2021
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Qiang Chen, Ming Yang, Huafang Lai
  • Patent number: 11124797
    Abstract: The present invention provides a novel gene WMS conferring wheat male sterility, its anther-specific expression promoter, and uses of the same. In wheat, a well-known gene Ms2 causing dominant male sterility has been widely applied in recurrent selection in China. A RNA-seq approach was performed to reveal the anther-specific transcriptome in a pair of Ms2 isogenic lines, ‘Lumai 15’ and ‘Lumai 15+Ms2’. As a result, a WMS gene was identified showing anther-specific expression at the early stage of meiosis and only in wheat carrying the Ms2 gene. The regulation of WMS could alter plant male fertility. The promoter of WMS was found to comprise anther-specific activity. Thus, the present invention might be used to achieve anther-specific gene expression, to develop male sterility in various plant species, to establish recurrent selection in various plant species, and to assist hybrid seed production.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: September 21, 2021
    Assignee: SHANDONG AGRICULTURAL UNIVERSITY
    Inventors: Daolin Fu, Mincheng Luo, Juan Qi, Fei Ni, Bo Lv, Shuyun Wang
  • Patent number: 11124801
    Abstract: The compositions and methods disclosed relate to DNA compositions, plant cells, seeds, plant parts that relate to maize plants with increased grain yield trait. Also provided are assays for detecting the presence of the maize DP-202216-6 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: September 21, 2021
    Inventors: Nathan David Coles, Olga Danilevskaya, Jeffrey Habben, Mary A Rupe, Jeffrey R Schussler, Bo Shen, Benjamin P Weers, Jingrui Wu
  • Patent number: 11111499
    Abstract: Provided are isolated polynucleotides encoding a polypeptide at least 80% homologous to the amino acid sequence selected from the group consisting of SEQ ID NOs: 757, 456-756, 758-774, 8385-10836, and 10838-14462; and isolated polynucleotide comprising nucleic acid sequences at least 80% identical to SEQ ID NO: 377, 1-376, 378-455, and 775-8384. Also provided are nucleic acid constructs comprising same, isolated polypeptides encoded thereby, transgenic cells and transgenic plants comprising same and methods of using same for increasing yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, abiotic stress tolerance, and/or nitrogen use efficiency of a plant.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: September 7, 2021
    Assignee: Evogene Ltd.
    Inventors: Noa Matarasso, Eyal Emmanuel, David Panik, Inbal Nurith Dangoor, Hagai Karchi
  • Patent number: 11112409
    Abstract: The present disclosure relates generally to detection of contamination of a sample or diagnosis of subject based upon detection or quantification of amino acid sequences in a sample, specifically to the identification and use of molecular biomarkers for Candida albicans biofilm infections.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: September 7, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Clarissa Nobile, Michael Winter, Charles Craik, Alexander Johnson, Anthony O'Donoghue
  • Patent number: 11098320
    Abstract: The invention relates to high-protein-content soybeans and methods of producing high-protein-content soybeans. The methods can relate to proteome rebalancing and regulating the abscisic acid (ABA) pathway. The methods can relate to modulating transcription factors such as AiP2. AiP2 modification can increase soybean protein content and indicates the strategic path to alter seed protein is contained within the mechanisms of abscisic acid control of seed development.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: August 24, 2021
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventor: Eliot M. Herman
  • Patent number: 11089348
    Abstract: Aspects of the subject disclosure may include, for example, detecting, by a processing system including a processor, a transmission of a signal that identifies an advertisement, transmitting, by the processing system, a first indication of having detected the signal, and transmitting, by the processing system, a second indication of a status of the processing system when the signal is detected. Other embodiments are disclosed.
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: August 10, 2021
    Assignee: AT&T Intellectual Property I, L.P.
    Inventors: Thomas P. Benzaia, Bernard Ku, Lakshminarashimhan Naidu
  • Patent number: 11064670
    Abstract: The present invention is in the field of soybean variety CS1661395, CS1661278, CS1661219, CS1661171, CS1660654, AND/OR CS1661663 breeding and development. The present invention particularly relates to the soybean variety CS1661395, CS1661278, CS1661219, CS1661171, CS1660654, AND/OR CS1661663 and its seed, cells, germplasm, plant parts, and progeny, and methods of using CS1661395, CS1661278, CS1661219, CS1661171, CS1660654, AND/OR CS1661663 in a breeding program.
    Type: Grant
    Filed: January 27, 2020
    Date of Patent: July 20, 2021
    Assignee: Syngenta Crop Protection AG
    Inventor: Joseph William Strottman
  • Patent number: 11044883
    Abstract: A soybean cultivar designated 1361091 is disclosed. Embodiments include the seeds of soybean 1361091, the plants of soybean 1361091, to plant parts of soybean 1361091, and methods for producing a soybean plant produced by crossing soybean 1361091 with itself or with another soybean variety. Embodiments include methods for producing a soybean plant containing in its genetic material one or more genes or transgenes and the transgenic soybean plants and plant parts produced by those methods. Embodiments also relate to soybean cultivars, breeding cultivars, plant parts, and cells derived from soybean 1361091, methods for producing other soybean cultivars, lines or plant parts derived from soybean 1361091, and the soybean plants, varieties, and their parts derived from use of those methods. Embodiments further include hybrid soybean seeds, plants, and plant parts produced by crossing 1361091 with another soybean cultivar.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: June 29, 2021
    Assignee: Benson Hill Seeds, Inc.
    Inventor: William K. Rhodes
  • Patent number: 11046978
    Abstract: This disclosure generally relates to the use of enzyme combinations or recombinant microbes comprising same to make isoprenoid precursors, isoprenoids and derivatives thereof including prenylated aromatic compounds. Novel metabolic pathways exploiting Claisen, aldol, and acyioin condensations are used instead of the natural mevalonate (MVA) pathway or 1-deoxy-d-xylulose 5-phosphate (DXP) pathways for generating isoprenoid precursors such as isopentenyl pyrophosphate (IPP), dimethylallyl pyrophosphate (DMAPP), and geranyl pyrophosphate (GPP). These pathways have the potential for better carbon and or energy efficiency than native pathways. Both decarboxylative and non-carboxylative condensations are utilized, enabling product synthesis from a number of different starting compounds.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: June 29, 2021
    Assignee: WILLIAM MARSH RICE UNIVERSITY
    Inventors: Ramon Gonzalez, James M. Clomburg, Seokjung Cheong
  • Patent number: 11046965
    Abstract: The present invention provides a method which can replace Agrobacterium techniques and which can efficiently produce transformed cells of a rubber-producing plant. The present invention relates to a method of producing transformed cells of a rubber-producing plant, which includes steps a) to e).
    Type: Grant
    Filed: June 12, 2019
    Date of Patent: June 29, 2021
    Assignee: SUMITOMO RUBBER INDUSTRIES, LTD.
    Inventors: Haruhiko Yamaguchi, Yukino Inoue, Teruhiko Terakawa, Tsubasa Yano
  • Patent number: 11046971
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a HPPD-inhibiting herbicide and/or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a HPPD-inhibiting herbicide, applying to said site an effective amount of said herbicide. The invention further refers to plants comprising mut-HPPD, and methods of obtaining such plants.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: June 29, 2021
    Inventors: Maciej Pasternak, Stefan Tresch, Johannes Hutzler, Jens Lerchl, Thomas Mietzner, Brigitte Weston, Matthias Witschel, Jill Marie Paulik
  • Patent number: 11041143
    Abstract: Numerous plant microbes, including the vascular-limited Candidatus spp.—causal agents of citrus greening and potato zebra chip diseases—are non-culturable. The present disclosure relates, according to some embodiments, to compositions, methods and systems for culturing such organisms. For example, the present disclosure relates to methods for culturing, propagating, and characterizing fastidious vascular-colonizing microbes using a hairy root system (e.g., in vitro, in planta). The present disclosure relates, in some embodiments, to methods for cultivating a fastidious plant microbe including: contacting a plant (e.g., a tomato plant, a potato plant, a citrus plant) colonized by a fastidious plant microbe (e.g., Xylella fastidiosa, Candidatus Liberibacter spp.) with a suspension of R. rhizogenes under conditions that permit induction of hairy roots colonized with the fastidious plant microbe, and propagating the colonized microbial hairy roots.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: June 22, 2021
    Assignee: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Kranthi K. Mandadi, Sonia C. Irigoyen, T. Erik Mirkov
  • Patent number: 11039586
    Abstract: The current invention provides methods for creating a block of genetically linked transgenic traits or a megalocus that can be transmitted as a single genetic unit. The present invention further provides methods for trait introgression to other plants, varieties or species using the megaloci of the invention. Also provided are plants, seeds, and plant parts comprising the megaloci.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: June 22, 2021
    Assignee: Monsanto Technology LLC
    Inventors: Paul S. Chomet, Jonathan C. Lamb, Richard J. Lawrence
  • Patent number: 11034726
    Abstract: The present invention relates to a peptide comprising or consisting of an amino acid sequence according to formula (I) X1-X2-X3-X4-X5-(A)m-X6-X7-(X8)n-C (I), wherein X1 is C or S, X2 is L or A, X3 is A, V or L, X4 is F or Y, X5 is Y or F, X6 is C or R, X7 is F or L, X8 is W or A and m and n are independently 0 or 1 or a variant thereof.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: June 15, 2021
    Assignee: PIVARIS BIOSCIENCE GMBH
    Inventor: Hanna Harant
  • Patent number: 11028405
    Abstract: The present invention relates to isolated nucleic acid molecules and their corresponding encoded polypeptides able confer the trait of improved plant size, vegetative growth, growth rate, seedling vigor and/or biomass in plants challenged with saline and/or oxidative stress conditions. The present invention further relates to the use of these nucleic acid molecules and polypeptides in making transgenic plants, plant cells, plant materials or seeds of a plant having plant size, vegetative growth, growth rate, seedling vigor and/or biomass that are improved in saline and/or oxidative stress conditions with respect to wild-type plants grown under similar conditions.
    Type: Grant
    Filed: January 23, 2020
    Date of Patent: June 8, 2021
    Assignee: Ceres, Inc.
    Inventors: Fasong Zhou, Kenneth A. Feldmann, Julissa Sosa
  • Patent number: 11021714
    Abstract: Methods and materials for modulating cold tolerance levels in plants are disclosed. For example, nucleic acids encoding cold tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased levels of cold tolerance and plant products produced from plants having increased cold tolerance levels.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: June 1, 2021
    Assignee: Ceres, Inc.
    Inventors: Cory Christensen, Jack Okamuro, Shing Kwok, Roger Pennell
  • Patent number: 11014960
    Abstract: The present invention relates to peptides, and amino acid and peptide conjugates, methods for making amino acid and peptide conjugates, conjugates produced by the methods, pharmaceutical compositions comprising the peptides and conjugates, methods of eliciting immune responses in a subject and methods of vaccinating a subject, uses of the peptides and conjugates for the same, and uses of the peptides and conjugates in the manufacture of medicaments for the same.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: May 25, 2021
    Assignee: AUCKLAND UNISERVICES LIMITED
    Inventors: Margaret Anne Brimble, Peter Roderick Dunbar, Geoffrey Martyn Williams, Daniel Verdon
  • Patent number: 11015206
    Abstract: Compositions and methods comprising polynucleotides and polypeptides having 4-hydroxyphenylpyruvate dioxygenase (HPPD) activity and having insensitivity to an HPPD inhibitor are provided. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the HPPD sequences. Various methods of employing the HPPD sequences are provided. Such methods include, for example, methods for producing an HPPD inhibitor tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein. Methods are also provided to identify additional HPPD variants. Further provided are various methods and compositions that allow the various HPPD polypeptides and variant and fragments thereof to be expressed in a chloroplast or transported to a chloroplast.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: May 25, 2021
    Inventors: Phillip A Patten, Daniel Siehl, Yumin Tao, Henrik Albert, Ericka Bermudez, Linda A Castle, Yuxia Dong, Andrew Duncan Satterfield
  • Patent number: 11008584
    Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: May 18, 2021
    Assignee: Ceres, Inc.
    Inventors: Gregory Nadzan, Richard Schneeberger, Han Suk Kim, David Van-Dinh Dang, Kenneth A. Feldmann
  • Patent number: 11008580
    Abstract: This invention provides molecular constructs and methods for the temporally specific control of gene expression in plants or in plant pests or pathogens. More specifically, this invention provides plant miRNA genes having novel circadian expression patterns that are useful for designing recombinant DNA constructs for temporally specific expression of at least one gene. Also provided are non-natural transgenic plant cells, plants, and seeds containing in their genome a recombinant DNA construct of this invention.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: May 18, 2021
    Assignee: MONSANTO TECHNOLOGY LLC
    Inventors: Edwards M. Allen, Sara E. Heisel, Sergey Ivashuta, Elysia K. Krieger, Jennifer Lutke, Robert J. Meister, Yuanji Zhang
  • Patent number: 11001849
    Abstract: Methods and materials for increasing abiotic stress tolerance in plants are disclosed. For example, nucleic acids encoding abiotic stress tolerance-increasing polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased tolerance to abiotic stress and methods of increasing plant yield under abiotic stress conditions.
    Type: Grant
    Filed: September 19, 2019
    Date of Patent: May 11, 2021
    Assignee: CERES, INC.
    Inventors: Roger I. Pennell, Wuyi Wang, Chuan-Yin Wu, Dwarkesh Parihar, Paresh Verma, Vijay R. Kumar, Shridhar J. Rao
  • Patent number: 10988514
    Abstract: Methods and apparatus for identifying and screening hydrogen bond networks are provided. A computing device can determine a search space for hydrogen bond networks related to one or more molecules, where the search space can include a plurality of energy terms related to a plurality of residues related to the hydrogen bond networks. The computing device can search the search space to identify one or more hydrogen bond networks based on the plurality of energy terms. The computing device can screen the identified hydrogen bond networks to identity one or more screened hydrogen bond networks based on scores for the identified hydrogen bond networks. An output can be generated that is related to the one or more screened hydrogen bond networks. Also provided are polypeptides that can form homo-oligomers with modular hydrogen bond network-mediated specificity.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: April 27, 2021
    Assignee: University of Washington
    Inventors: David Baker, Scott Boyken, Zibo Chen, Chunfu Xu, Sherry Bermeo, Robert Langan
  • Patent number: 10982218
    Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: April 20, 2021
    Assignee: Mendel Biotechnology, Inc.
    Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
  • Patent number: 10982224
    Abstract: Provided are isolated polynucleotides encoding a polypeptide at least 80% homologous to the amino acid sequence selected from the group consisting of SEQ ID NOs: 799, 488-798, 800-813, 4852-5453, 5460, 5461, 5484, 5486-5550, 5553, and 5558-8091; and isolated polynucleotide comprising nucleic acid sequences at least 80% identical to SEQ ID NO: 460, 1-459, 461-487, 814-1598, 1600-1603, 1605-1626, 1632-1642, 1645-4850 or 4851. Also provided are nucleic acid constructs comprising same, isolated polypeptides encoded thereby, transgenic cells and transgenic plants comprising same and methods of using same for increasing yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, abiotic stress tolerance, and/or nitrogen use efficiency of a plant. Also provided are isolated polynucleotides comprising the nucleic acid sequence set forth by SEQ ID NO:8096, wherein the isolated polynucleotide is capable of regulating expression of at least one polynucleotide sequence operably linked thereto.
    Type: Grant
    Filed: April 4, 2019
    Date of Patent: April 20, 2021
    Assignee: Evogene Ltd.
    Inventors: Zur Granevitze, Hagai Karchi
  • Patent number: 10968461
    Abstract: The present invention relates to isolated nucleic acid molecules and their corresponding encoded polypeptides able confer the trait of improved plant size, vegetative growth, growth rate, seedling vigor and/or biomass in plants challenged with saline conditions. The present invention further relates to the use of these nucleic acid molecules and polypeptides in making transgenic plants, plant cells, plant materials or seeds of a plant having plant size, vegetative growth, growth rate, seedling vigor and/or biomass that are improved in saline conditions with respect to wild-type plants grown under similar conditions.
    Type: Grant
    Filed: August 28, 2019
    Date of Patent: April 6, 2021
    Assignee: CERES, INC.
    Inventors: Fasong Zhou, Kenneth A. Feldmann, Julissa Sosa
  • Patent number: 10961542
    Abstract: The present invention relates to a new promoter of the expression of genes in plants. More specifically, the invention relates to regulatory sequences of polynucleotides that are isolated from soy plants and can initiate and activate polynucleotide transcription, and to the use of these regulatory sequences to modify the transcription of endogenous and/or heterologous polynucleotides and to produce polypeptides. The invention further describes DNA constructs that contain the promoter of the gene of the supposed flavonol-sulfotransferase protein in soy plants, which promoter is functionally linked to a heterologous and/or endogenous gene. Moreover, the invention relates to the use of these constructs in the form of expression cassettes, expression vectors, recombinant vectors and in plants, plant cells or transgenic protoplasts.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: March 30, 2021
    Assignees: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA—EMBRAPA, FUNDACAO UNIVERSIDADE DE BRASILIA
    Inventors: Juliana Dantas de Almeida, Leila Maria Gomes Barros, Renata Henrique Santana, Ricardo Vilela Abdelnoor, Felipe Rodrigues da Silva
  • Patent number: 10945391
    Abstract: Methods for introgressing an allele of interest of a locus associated with a yield trait into Zea mays germplasm are provided. In some embodiments, the methods include providing a Zea mays plant that contains an allele of interest of a locus associated with a yield trait, wherein the locus associated with the yield trait is identifiable by PCR amplification of a Zea mays nucleic acid with a pair of oligonucleotides primers as disclosed herein, and introgressing the allele of interest into Zea mays germplasm that lacks the allele. Also provided are methods for identifying Zea mays plants that contain at least one allele associated with improved yield, improved maize plants, elite Zea mays plants, biomass produced from improved Zea mays plants, isolated and purified genetic markers, and compositions that include an amplification primer pair capable of amplifying a Zea mays nucleic acid to generate a Zea mays marker amplicon.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: March 16, 2021
    Assignee: Syngenta Participations AG
    Inventors: Venkata Krishna Kishore, Libardo Andres Gutierrez-Rojas, Zhigang Guo, Joseph Richard Byrum
  • Patent number: 10946084
    Abstract: The present invention relates to proteins and nucleic acids derived from Staphylococcus aureus as well as therapeutic and diagnostic uses of the proteins and nucleic acids.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: March 16, 2021
    Assignee: Evaxion Biotech ApS
    Inventors: Niels Iversen Møller, Andreas Holm Mattsson
  • Patent number: 10925923
    Abstract: The present invention provides a peptide having anti-inflammatory activity, composed of an amino acid sequence of a sequence listing of SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 3. The peptide inhibits the expression of inflammatory cytokines and inhibits the proliferation of inflammatory cells, so as to resultantly exhibit anti-inflammatory activity, thereby being useful in the prevention or treatment of inflammatory diseases.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: February 23, 2021
    Assignee: CAREGEN CO., LTD.
    Inventors: Yong Ji Chung, Eun Mi Kim
  • Patent number: 10918072
    Abstract: The invention relates to the novel cotton variety designated 17R814B3XF. Provided by the invention are the seeds, plants, plant parts and derivatives of the cotton variety 17R814B3XF. Also provided by the invention are methods of using cotton variety 17R814B3XF and products derived therefrom. Still further provided by the invention are methods for producing cotton plants by crossing the cotton variety 17R814B3XF with itself or another cotton variety and plants and seeds produced by such methods.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: February 16, 2021
    Assignee: Monsanto Technology LLC
    Inventor: Robert E. McGowen
  • Patent number: 10907169
    Abstract: Methods and materials for increasing abiotic stress tolerance in plants are disclosed. For example, nucleic acids encoding abiotic stress tolerance-increasing polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased tolerance to abiotic stress and methods of increasing plant yield under abiotic stress conditions.
    Type: Grant
    Filed: September 19, 2019
    Date of Patent: February 2, 2021
    Assignee: CERES, INC.
    Inventors: Roger I. Pennell, Wuyi Wang, Chuan-Yin Wu, Dwarkesh Parihar, Paresh Verma, Vijay R. Kumar, Shridhar J. Rao
  • Patent number: 10889827
    Abstract: Provided are isolated polypeptides which are at least 80% homologous to SEQ ID NO: 474-643, 645-679, 681-755, 757-760, 4806-6390, 6395-6396, 6401-6895, 6897-7249, 7251-7685, 7687-7693, 7695-7700, 7702-7708, 7710-7796, 7798-7816, 7818, 7820-7837, 7839-7840, 7842-7861, 7863-8134, 8136-8163 or 8164, isolated polynucleotides which are at least 80% identical to SEQ ID NOs: 1-170, 172-267, 269-424, 426-473, 761-2486, 2489-2494, 2496-4803 or 4804, nucleic acid constructs comprising same, transgenic cells expressing same, transgenic plants expressing same and method of using same for increasing yield, harvest index, abiotic stress tolerance, growth rate, biomass, vigor, oil content, photosynthetic capacity, seed yield, fiber yield, fiber quality, fiber length, and/or nitrogen use efficiency of a plant.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: January 12, 2021
    Assignee: Evogene Ltd.
    Inventors: Ilya Pankratov, Hagai Karchi
  • Patent number: 10883112
    Abstract: The invention relates to plants wherein the protein OSD1, involved in the transition from meiosis I to meiosis II is inactive. These plants produce Second Division Restitution (SDR) 2n gametes. The invention further relates to plants wherein the inactivation of OSD1 is combined with the inactivation of a gene involved in meiotic recombination in plants, and of a gene involved in the monopolar orientation of the kinetochores during meiosis. These plants produce apomeiotic gametes. These plants are useful in plant breeding.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: January 5, 2021
    Assignee: Institut National de Recherche Pour l'Agriculture, l'Alimentation et l'Environnement
    Inventors: Raphael Mercier, Isabelle D'Erfurth, Nicole Froger, Sylvie Jolivet, Laurence Cromer