With Control Means Responsive To Sensed Condition Patents (Class 96/102)
  • Patent number: 10895558
    Abstract: A flow controller having high workability and a gas chromatograph equipped with the same are provided. A carrier gas controller is equipped with a flow path member. The flow path member is equipped with a first portion and a second portion extending horizontally from an upper end portion of the first portion. In the second portion, a gas outlet port is formed. An H2 gas controller is equipped with a flow path member. The flow path member is equipped with a first portion and a second portion extending horizontally from an upper end portion of the first portion. In the second portion, a gas outlet port is formed. For this reason, a sufficient working space for the gas outlet port can be secured. Further, a sufficient working space for the gas outlet port can be secured. In other words, the workability with respect to the carrier gas controller and the H2 gas controller can be kept high.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: January 19, 2021
    Assignee: Shimadzu Corporation
    Inventor: Kiyonori Koga
  • Patent number: 9772263
    Abstract: A sampling system includes an analyte sampler that includes an enclosure; a mount disposed in the enclosure; a capillary tube disposed in the mount; and a thermal member disposed in the enclosure and including a first fluid supply member to provide a fluid to an interior of the enclosure. The sampling system also includes a manifold in fluid communication with the analyte sampler. A process for sampling an analyte includes subjecting the capillary tube to a negative pressure; and controlling the temperature of the capillary tube to immobilize the analyte in the capillary tube; providing an analyte to a second end of the capillary tube; and immobilizing the analyte in the capillary tube to sample the analyte.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: September 26, 2017
    Assignee: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventor: Thomas J. Bruno
  • Publication number: 20150040756
    Abstract: Exemplary embodiments of the present disclosure include systems, apparatuses, and methods that are directed to controlling pressure in a pressurized flow system, such as a C02-based chromatography system or other pressurized flow systems. Exemplary embodiments of the present disclosure comprise one or more apparatuses, systems or methods for implementing multiple pressure regulators to control pressure. In addition to providing pressure control, apparatuses, systems and methods described herein dampen damaging thermal effects caused by pressure drops of a mobile phase including C02.
    Type: Application
    Filed: March 7, 2013
    Publication date: February 12, 2015
    Inventors: Joshua A. Shreve, John Maillet, JR., Steven D. Trudeau, Paul Linderson
  • Publication number: 20140298990
    Abstract: The present disclosure provides adaptive methods for gas chromatography analysis of a gas sample comprising one or more target analytes (such as a micro-gas chromatography) and adaptive gas chromatography devices for carrying out such analytical methods. Broadly, the system can regulate flow into a downstream chromatographic column by detecting one or more upstream conditions. For example, one adaptive chromatography device comprises a first column, a modulator component, and a second column. A first detector or sensor detects the presence of target analytes upstream from the second column, while a second detector detects the presence of target analytes eluted from the second column. The modulator component assembly is responsive to an output generated by the first detector and adaptively regulates fluid flow into the second column. Such adaptive chromatography (micro-GC) systems have higher separation speed, better analyte identification capability, and far greater energy savings.
    Type: Application
    Filed: November 8, 2012
    Publication date: October 9, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Xudong Fan, Yogesh B. Gianchandani, Jing Liu
  • Publication number: 20140290491
    Abstract: A housing of a column unit is tubular-shaped, and includes a first opening and a second opening, and an inner space separated from outside air by an insulating material. An air cooling section including a cooling device is arranged on a side of the first opening of the housing. At the time of cooling the inside of the inner space of the housing, air is caused, by a fan, to flow through the air cooling section and from the side of the first opening to a side of the second opening. A column section including a separation column and a heater is arranged inside the housing. A gap through which air flows from the first opening to the second opening is formed between the column section and an inner wall of the inner space of the housing.
    Type: Application
    Filed: March 26, 2014
    Publication date: October 2, 2014
    Applicant: SHIMADZU CORPORATION
    Inventors: Masaki Kanai, Takahiro Nishimoto, Masanori Nishino, Satoshi Matsuoka
  • Publication number: 20140216134
    Abstract: Embodiments of an apparatus including a front-end pre-concentrator module including an inlet, an outlet, and at least one valve to control flow through the inlet, the outlet, or both. The apparatus includes a back-end pre-concentrator module including an inlet, an outlet, and at least one valve to control flow through the inlet, the outlet, or both, and also includes a gas analysis module having an inlet and an outlet and including a gas chromatograph having an inlet and an outlet. The outlet of the front-end pre-concentrator and the outlet of the back-end pre-concentrator are coupled to the inlet of the gas analysis module. Other embodiments are also disclosed and claimed.
    Type: Application
    Filed: April 8, 2014
    Publication date: August 7, 2014
    Applicant: TricornTech Corporation
    Inventors: Tsung-Kuan A. Chou, Li-Peng Wang, Chia-Jung Lu, Shih-Chi Chu
  • Patent number: 8668868
    Abstract: A method for abating effluent from an electronic device manufacturing process is provided, including abating the effluent in a thermal abatement tool to form abated effluent; determining whether the abated effluent contains one or more chemical species of interest; and changing one or more operating parameters of the thermal abatement tool based upon the determination. Numerous other embodiments are provided.
    Type: Grant
    Filed: October 25, 2008
    Date of Patent: March 11, 2014
    Assignee: Applied Materials, Inc.
    Inventors: Ho-Man Rodney Chiu, Daniel O. Clark, Shaun W. Crawford, Jay J. Jung, Youssef A. Loldj, Robbert M. Vermeulen
  • Patent number: 8591634
    Abstract: An apparatus and process for recovering a desired gas such as xenon difluoride, xenon, argon, helium or neon, from the effluent of a chemical process reactor that utilizes such gases alone or in a gas mixture or in a molecule that becomes decomposed wherein the chemical process reactor uses a sequence of different gas composition not all of which contain the desired gas and the desired gas is captured and recovered substantially only during the time the desired gas is in the effluent.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: November 26, 2013
    Assignee: Air Products and Chemicals, Inc.
    Inventors: David Charles Winchester, Matthew John Bosco, Gerald W. Klein, Isaac Patrick West, Richard Linton Samsal, Douglas Paul Dee, Andrew David Johnson, Eugene Joseph Karwacki, Jr.
  • Publication number: 20130180405
    Abstract: A multicapillary bundle for use in a gas chromatograph. Each of the capillaries in the bundle is formed using a coating solution containing a stationary phase and a solvent. The capillaries are coated with stationary phase by reducing pressure at a vacuum end of the capillary and creating a moving interface between the coating solution and a film of stationary phase deposited on each of the capillaries. The reducing pressure at the vacuum end of the capillary and the temperature of the capillary are controlled to maintain motion of the moving interface away from the vacuum end of the capillary. Maintained movement of the interface prevents recoating of the stationary phase. A heating wire and capillaries are embedded in a thermally conductive polymer to create a highly responsive method of heating the multicapillary column. An electronic control device controls the feedback temperature of the multicapillary column using the heating wire.
    Type: Application
    Filed: January 13, 2012
    Publication date: July 18, 2013
    Inventors: Ron W. Currie, David Christiansen
  • Patent number: 8414832
    Abstract: The invention is a chromatography apparatus which comprises at least one capillary column, which has a coil assembly of column material and a small diameter wire coated with an electrically insulating high temperature material encased within a high temperature sheath. The small diameter wire is at least one electrically conductive element co-linear with the column material. Also provided is means for directly resistively heating the at least one capillary column, and means for controlling the temperature of the capillary column. Additionally, the apparatus includes an oxygen gas containing inlet, a hydrogen inlet, an analyte port and a flame region, oxygen delivery means for delivering oxygen through the oxygen inlet to the flame region, a hydrogen and analyte delivery system for delivering hydrogen and analyte to the flame region, and a detector arranged to detect flame emission.
    Type: Grant
    Filed: September 8, 2009
    Date of Patent: April 9, 2013
    Inventors: Ned Roques, John Crandall
  • Publication number: 20130068100
    Abstract: The present invention refers to a modulator, to be used for comprehensive multidimensional chromatography separations to entrap and release sample solute fractions (entrapped in a capillary loop of fixed or variable volume), deriving from a capillary column with an internal diameter ranging from 0.01 mm to 0.53 mm, onto another capillary column with an internal diameter ranging from 0.01 mm to 0.53 mm. The micro-device has been integrated in a gas chromatographic system, composed of two ovens for the independent temperature control of the two columns; the micro-device is characterized, internally, by a system of channels that enable the controlled splitting of gas flow, entering the second capillary, to generate an optimum gas linear velocity and to release the pressure in excess, with the objective of attaining the maximum separation efficiency in the second column.
    Type: Application
    Filed: May 24, 2011
    Publication date: March 21, 2013
    Inventor: Luigi Mondello
  • Patent number: 8398851
    Abstract: The invention relates to a device and to a method for determining the proportion of fuel in a combustion engine lubricating oil. The device according to the invention comprises a column (12) with at least 22000 theoretical plates and a steady state phase capable of separating the fuel, the oil, the internal standard contained in the oil and the solvent, in which the oil and the internal standard are diluted, and a heating module (120) capable of causing an increase in the temperature of the column (12) at a rate of at least 350° C./min. In the method according to the invention, the column (12) is subjected to determined cycles during which the pressure of the carrier gas and the temperature are varied.
    Type: Grant
    Filed: July 7, 2008
    Date of Patent: March 19, 2013
    Assignee: Renault S.A.S.
    Inventors: Laurent Tiquet, Pierrick Rouille
  • Patent number: 8389289
    Abstract: A gas chromatograph (GC) apparatus capable of detecting abnormality, in which a reference retention index is obtained from a result obtained by analyzing a given substance and a retention-index reference substance under adequate analysis conditions using a normal column, and stored in a storage section. Further, under a condition that the apparatus can perform normal analysis, the given substance is subjected to GC analysis to obtain a reference retention time, and the obtained reference retention time is stored in the storage section. A diagnosis processing section is operable to compare each of an actual retention time and an actual retention index with a respective one of the reference retention time and the reference retention index. If a deviation therebetween or abnormality is detected, the diagnosis processing section is operable to estimate a causal factor of the abnormality.
    Type: Grant
    Filed: September 10, 2009
    Date of Patent: March 5, 2013
    Assignee: Shimadzu Corporation
    Inventor: Shuichi Kawana
  • Patent number: 8357234
    Abstract: An apparatus and method for rapid fractionation of hydrocarbon phases in a sample fluid stream are disclosed. Examples of the disclosed apparatus and method include an assembly of elements in fluid communication with one another including one or more valves and at least one sorbent chamber for removing certain classifications of hydrocarbons and detecting the remaining fractions using a detector. The respective ratios of hydrocarbons are determined by comparison with a non separated fluid stream.
    Type: Grant
    Filed: July 21, 2010
    Date of Patent: January 22, 2013
    Assignee: UT-Battelle, LLC
    Inventors: Charles S. Sluder, John M. Storey, Samuel A. Lewis, Sr.
  • Patent number: 8343258
    Abstract: A device for providing a constant mass flow rate to a downstream column system of a gas chromatograph includes a small full scale mass flow controller that controls carrier gas to flow at a first mass flow rate and a flow resistance element, including an inlet port connected to a sample inlet, an outlet port connected to the downstream column system, and a pressure sensing port in fluid communication with the outlet port and the mass flow controller. A sample inlet pressure controller controls the sample inlet at a first pressure, and a pressure sensor measures a second pressure of the carrier gas at the pressure sensing port. A set point of the first pressure is determined as a function of the second pressure, flow resistance of the flow resistance element, and a second mass flow rate from the inlet port to the outlet port of the flow resistance element.
    Type: Grant
    Filed: March 30, 2010
    Date of Patent: January 1, 2013
    Assignee: Agilent Technologies, Inc.
    Inventor: Xiaosheng Guan
  • Patent number: 8308854
    Abstract: A system for recycling helium carrier gas comprises: a bladder, the bladder interior fluidically configured so as to receive helium-bearing gas output from at least one of a split vent and a septum purge vent of a gas chromatograph; a compartment containing the bladder; a source of pressurized air or gas operable so as to supply pressurized air or gas into the compartment interior so as to compress the bladder containing the helium-bearing gas; a gas reservoir fluidically coupled to the bladder interior so as to receive the helium bearing gas from the compressed bladder interior; and at least one gas purification module configured so as to receive the helium-bearing gas from the gas reservoir and operable to remove contaminants from the helium-bearing gas, an output of the at least one gas purification module being fluidically coupled to a carrier gas inlet of the gas chromatograph.
    Type: Grant
    Filed: December 15, 2009
    Date of Patent: November 13, 2012
    Assignee: Thermo Finnigan LLC
    Inventors: Edward B. McCauley, Matt A. Lasater
  • Patent number: 8226825
    Abstract: Systems and methods for performing chromatography separations or analyses are disclosed. The methods are based upon an equilibrium gradient focusing mode in contrast to conventional transient migration-based modes. By matching the migration speed of one or more analyte(s) of interest to the wave speed of a thermal gradient induced to travel along a region in which chromatographic partitioning occurs, significant improvements in detection limits are achieved. In particular, a temperature gradient focusing strategy is described in which analyte(s) of interest are circulated around a continuous chromatography system in order to focus the analyte(s). Also described are various devices and systems that can be used in the methods described herein.
    Type: Grant
    Filed: July 21, 2009
    Date of Patent: July 24, 2012
    Assignee: The United States of America, as represented by the Sectretary of Commerce, The National Institute of Standards and Technology
    Inventor: David J. Ross
  • Publication number: 20120118144
    Abstract: A portable gas chromatography system and method of use. The portable gas chromatograph may be used to accurately and rapidly detect low-level concentrations of chemicals, such as fixed gases, volatilized liquid samples, or toxic chemicals and transmit to a user data relating to the presence and identity of such. The portable gas chromatograph uses an onboard vacuum source to pull samples into and through the system and thus does not require the use of a carrier gas. Further, the system comprises a solenoid valve for capturing the sample and may include a short porous layer open tubular separation column, and a thermal conductivity detector. Overall size and weight of the system is small enough for a user to carry. The method of operation of the gas chromatograph includes taking rapid successive samples and analyzing the data outputs using Fourier transform techniques. Such analysis allows real-time data updates and rapid detection of hazardous environmental agents.
    Type: Application
    Filed: November 12, 2010
    Publication date: May 17, 2012
    Applicant: MEADOWORKS, INC.
    Inventor: Marion H. Cates
  • Patent number: 8114200
    Abstract: A portable multi-dimensional gas chromatograph, the gas chromatograph including a carrier gas container, a regulator fluidly connected to the carrier gas container, a dopant chamber containing a reference chemical, at least one pre-concentrator which is fluidly connected to the regulator and the dopant chamber, a first separation column fluidly connected to the at least one pre-concentrator, a second separation column fluidly connected to the at least one pre-concentrator, a first detector fluidly connected to the first separation column, and a second detector fluidly connected to the second separation column.
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: February 14, 2012
    Assignee: VPI Enigineering, Inc.
    Inventors: Sheena Alm, James Bentley, John Blankevoort, Mark Kaspersen, Collin Lewis, Derek Maxwell, Ken Wunner
  • Patent number: 8104326
    Abstract: A gas chromatography system comprising a sample introduction device, an oven coupled to the sample introduction device and a detector coupled to the oven is disclosed. In certain examples, the oven may be configured to receive a chromatography column in a space in the oven. In some examples, the oven may be constructed and arranged to provide a substantially constant temperature to the space during an analysis stage of the gas chromatography system.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: January 31, 2012
    Assignee: PerkinElmer LAS, Inc.
    Inventors: Andrew Tipler, James Botelho, Avinash Dalmia, Michael J. Rafa, John Vanderhoef, Paul Schallis, Neal Green, David J. Scott, John McCaffrey, Paul St. Cyr, E. Joel McCorkle, Guiseppe Coppola
  • Publication number: 20120017760
    Abstract: An apparatus and method for rapid fractionation of hydrocarbon phases in a sample fluid stream are disclosed. Examples of the disclosed apparatus and method include an assembly of elements in fluid communication with one another including one or more valves and at least one sorbent chamber for removing certain classifications of hydrocarbons and detecting the remaining fractions using a detector. The respective ratios of hydrocarbons are determined by comparison with a non separated fluid stream.
    Type: Application
    Filed: July 21, 2010
    Publication date: January 26, 2012
    Applicant: UT-BATTELLE, LLC
    Inventors: Charles S. Sluder, John M. Storey, Samuel A. Lewis, SR.
  • Patent number: 8075768
    Abstract: A liquid chromatograph device was provided wherein operations inside a thermostatic chamber can be safely performed even while a heat block is being heated. The liquid chromatograph device comprises: a thermostatic chamber; outer doors and that are disposed at the front surface of the thermostatic chamber; a heat block; heater for heating said heat block; temperature sensor for the heat block; flowing means for flowing air between the inside and outside of the thermostatic chamber; a control means for controlling the supply of power to the heater based on the result of the temperature sensor; and an inner door between the outer door and the heat block, the inner door comprising a hollow inner door main body, a heat-insulating material that is housed within the inner door so as to form an air chamber between the heat-insulating material and the surface of the outer door of the inner door main body and inlet/outlet slits and that are formed in the inner door main body.
    Type: Grant
    Filed: May 13, 2011
    Date of Patent: December 13, 2011
    Assignee: Shimadzu Corporation
    Inventor: Takao Okado
  • Publication number: 20110271838
    Abstract: A microtrap assembly includes a carbon nanotube sorbent. The microtrap assembly may be employed as a preconcentrator operable to deliver a sample to an analytical device to measure the concentrations of greenhouse gases. A system includes a microtrap having a carbon nanotube sorbent for measuring the concentrations of greenhouse gases in a sample.
    Type: Application
    Filed: April 13, 2011
    Publication date: November 10, 2011
    Applicant: New Jersey Institute of Technology
    Inventors: Somenath Mitra, Chutarat Saridara
  • Publication number: 20110239860
    Abstract: A device for providing a constant mass flow rate to a downstream column system of a gas chromatograph includes a small full scale mass flow controller that controls carrier gas to flow at a first mass flow rate and a flow resistance element, including an inlet port connected to a sample inlet, an outlet port connected to the downstream column system, and a pressure sensing port in fluid communication with the outlet port and the mass flow controller. A sample inlet pressure controller controls the sample inlet at a first pressure, and a pressure sensor measures a second pressure of the carrier gas at the pressure sensing port. A set point of the first pressure is determined as a function of the second pressure, flow resistance of the flow resistance element, and a second mass flow rate from the inlet port to the outlet port of the flow resistance element.
    Type: Application
    Filed: March 30, 2010
    Publication date: October 6, 2011
    Applicant: AGILENT TECHNOLOGIES, INC.
    Inventor: Xiaosheng Guan
  • Patent number: 7947112
    Abstract: A method for degassing a fluid includes providing a degassing system having a degassing module and a fluid pump apparatus having a fluid reservoir, wherein the fluid pump apparatus is operated in a discontinuous mode involving one or more discrete pumping cycles having a first cycle time. The fluid pump apparatus is calibrated to deliver a predetermined volume of the fluid from the fluid reservoir during each of the pumping cycles, and the degassing module is adapted to operably move gas from the fluid to an extent sufficient to render the fluid volume to a desired degassed condition within a period of time that is not greater than the first cycle time.
    Type: Grant
    Filed: July 16, 2008
    Date of Patent: May 24, 2011
    Assignee: Rheodyne, LLC
    Inventors: Yuri Gerner, Carl W. Sims, Jonathan Thompson
  • Patent number: 7928370
    Abstract: An open probe method for sample introduction into a mass spectrometer is disclosed, comprising the steps of: loading a sample holder with sample compounds to be analyzed; heating a probe oven; introducing said sample compounds in said sample holder into said heated probe oven; flowing inert gas into said heated probe oven; vaporizing said sample in said heated probe oven by the combined effect of oven temperature and inert gas flow; entraining said vaporized sample in said inert gas; and, transferring said vaporized sample in inert gas into an ion source of a mass spectrometer; wherein said heated probe oven remains open to the ambient atmosphere during sample introduction and analysis; said inert gas is flowing in said heated probe oven in two directions of a transfer line to a mass spectrometer ion source and to the oven opening; said vaporized sample in inert gas is transferred through a heated transfer line directly into the ionization chamber of an ion source of a mass spectrometer.
    Type: Grant
    Filed: May 21, 2009
    Date of Patent: April 19, 2011
    Assignee: Aviv Amirav
    Inventors: Aviv Amirav, Alexander Gordin
  • Patent number: 7832253
    Abstract: A portable weather resistant gas chromatograph system with a gas chromatograph enclosure having a body and a movable door and a seal, a gas chromatograph with a frame assembly removably secured in the enclosure, a plurality of exhaust gas lines connected to the gas chromatograph, an explosion proof terminal box with circuit breakers and terminals mounted to the enclosure, a communication conduit and armored power cable between the explosion proof terminal box and the gas chromatograph, a purge gas conduit port for the gas chromatograph, a pedestal for the enclosure, and at least two lifting eyes connected to the enclosure.
    Type: Grant
    Filed: March 3, 2009
    Date of Patent: November 16, 2010
    Assignee: Solarcraft, Inc.
    Inventors: Darrell N. Haun, Donald N. Haun
  • Patent number: 7824478
    Abstract: Disclosed are systems and methods that include providing a vessel having an inlet and an outlet for communicating a carrier gas through the vessel; determining a differential pressure between the inlet and the outlet for a known flow rate at the outlet; and, determining a unit flow per unit pressure based on a ratio of the flow rate and the differential pressure. In certain embodiments, the flow rate at the outlet is established by controlling the flow rate of the gas. In some embodiments, the methods and systems can include a viscosity in the ratio, determining a flow rate at ambient pressure using a factor based on a ratio of a gas pressure at the output and ambient pressure, and/or, determining a flow rate at ambient temperature using a factor based on a ratio of a temperature at the output and ambient temperature.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: November 2, 2010
    Assignee: PerkinElmer Health Sciences, Inc.
    Inventors: Andrew Tipler, Neil T. Plant
  • Publication number: 20100251896
    Abstract: An apparatus, system, and method are disclosed for a gas chromatography (GC) system with a check valve. The check valve is situated downstream from the electronic flow control module and upstream of the injector. When a sample is volatized in the injector, the check valve closes into a checked position and prevents solvent and sample from backing into the gas delivery line. In certain embodiments, the check valve has a conical plug that fits into a seat that has an aperture. When the conical plug is depressed, the conical plug engages the sides of the aperture and seals the check valve, preventing solvent and sample from backing through the check valve. In certain embodiments, the change in pressure caused by over-pressurization in the injector, combined with the force applied by a spring on the conical plug, depresses the plug such that it seals the aperture.
    Type: Application
    Filed: April 1, 2009
    Publication date: October 7, 2010
    Inventor: Christopher Cameron Kellogg
  • Patent number: 7806963
    Abstract: An apparatus, system, and method are disclosed for broad spectrum chemical detection. The method includes detecting an ambient temperature and setting a target temperature based on the ambient temperature. The target temperature is a temperature greater than the ambient temperature. The method further includes determining elution data for the target temperature, either by selecting a target temperature at which elution data is available, or by interpolating between available sets of elution data. The method includes setting a preferred target temperature when an external power source is available, when faster sensor response is desired, and when higher resolution data is desired. The method further includes controlling the temperature of gas chromatography (GC) columns within a GC sensor to the target temperature.
    Type: Grant
    Filed: June 19, 2007
    Date of Patent: October 5, 2010
    Assignee: Seer Technology, Inc.
    Inventors: Neil S. Arnold, Gary Bodily
  • Publication number: 20100154511
    Abstract: A method and apparatus for two-dimensional gas chromatography (GC), including a valve having first and second positions (P1, and P2), and first through fourth sample flow paths (FP1-FP4). In P1, a first gas sample is collected from a first dimension GC column via FP1, a first pressure source and a first, second dimension GC column are connected via FP2, a second pressure source and a second, second dimension GC column are connected via FP3, and FP4 is disconnected. In P2, the first sample in FP1 is introduced to the second, second dimension GC column via FP1, with aid of the second pressure source, a second gas sample is collected from the first dimension GC column via FP2, the first pressure source and the first, second dimension GC column via FP4 are connected, and FP3 is disconnected.
    Type: Application
    Filed: December 14, 2009
    Publication date: June 24, 2010
    Inventors: Gordon Lambertus, William Steinecker
  • Publication number: 20100101411
    Abstract: Certain embodiments described herein are directed to chromatography systems that include a microfluidic device. The microfluidic device can be fluidically coupled to a switching valve to provide for selective control of fluid flow in the chromatography system. In some examples, the microfluidic device may include a charging chamber, a bypass restrictor or other features that can provide for added control of the fluid flow in the system. Methods of using the devices and methods of calculating lengths and diameters to provide a desired flow rate are also described.
    Type: Application
    Filed: May 27, 2009
    Publication date: April 29, 2010
    Inventor: Andrew Tipler
  • Patent number: 7691181
    Abstract: A system for controlling the flow rate into a chromatographic column is disclosed generally comprising communicating a fluid to the column through a transfer line, measuring the inlet pressure, determining the outlet pressure, and adjusting the applied pressure until the inlet and outlet pressures produce a desired flow rate for the transfer line outlet. In certain embodiments, the applied pressure is adjusted by controlling a proportional valve. In some embodiments, the outlet pressure is determined by measuring the pressure drop across the transfer line and calculating the outlet pressure from the measured inlet pressure and the pressure drop.
    Type: Grant
    Filed: December 11, 2008
    Date of Patent: April 6, 2010
    Assignee: PerkinElmer LAS, Inc.
    Inventors: Andrew Tipler, Richard G Edwards
  • Publication number: 20100005958
    Abstract: A flammable gas concentration device comprises an adsorption tower filled by an adsorbent for adsorbing a flammable gas; feeding means for feeding a raw gas containing air and a flammable gas to the adsorption tower via a feeding path and discharging an exhaust gas in the raw gas which has not been adsorbed to the adsorbent to an outside of the adsorption tower via a discharge path; collection means for reducing a pressure in the adsorption tower lower than an atmospheric pressure, and desorbing the flammable gas adsorbed by the adsorbent and collecting the flammable gas through a collection path; and control means for sequentially executing a flammable gas adsorption step of feeding the raw gas to the adsorption tower and discharging the exhaust gas from the adsorption tower by the feeding mean, and a flammable gas desorption step of collecting the flammable gas desorbed by the collection means.
    Type: Application
    Filed: October 11, 2007
    Publication date: January 14, 2010
    Applicants: OSAKA GAS CO., LTD., GAS AND POWER INVESTMENT CO., LTD.
    Inventors: Kenji Seki, Etsuo Shito, Katsuhiko Hirao
  • Publication number: 20090320560
    Abstract: Systems and methods for performing chromatography separations or analyses are disclosed. The methods are based upon an equilibrium gradient focusing mode in contrast to conventional transient migration-based modes. By matching the migration speed of one or more analyte(s) of interest to the wave speed of a thermal gradient induced to travel along a region in which chromatographic partitioning occurs, significant improvements in detection limits are achieved. In particular, a temperature gradient focusing strategy is described in which analyte(s) of interest are circulated around a continuous chromatography system in order to focus the analyte(s). Also described are various devices and systems that can be used in the methods described herein.
    Type: Application
    Filed: July 21, 2009
    Publication date: December 31, 2009
    Applicant: NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY
    Inventor: David J. Ross
  • Publication number: 20090308137
    Abstract: A multicapillary bundle for use in a gas chromatograph. Each of the capillaries in the bundle is formed using a coating solution containing a stationary phase and a solvent. The capillaries are coated with stationary phase by reducing pressure at a vacuum end of the capillary and creating a moving interface between the coating solution and a film of stationary phase deposited on each of the capillaries. The reducing pressure at the vacuum end of the capillary and the temperature of the capillary are controlled to maintain motion of the moving interface away from the vacuum end of the capillary. Maintained movement of the interface prevents recoating of the stationary phase. A heating wire and capillaries are embedded in a thermally conductive polymer to create a highly responsive method of heating the multicapillary column. An electronic control device controls the feedback temperature of the multicapillary column using the heating wire.
    Type: Application
    Filed: June 12, 2008
    Publication date: December 17, 2009
    Inventors: RON W. CURRIE, DAVID CHRISTIANSEN
  • Publication number: 20090293879
    Abstract: The invention relates to a medical device for producing oxygen, wherein the device comprises means for providing first conditions, and means for changing said first conditions to second conditions, the device being configured to during a charging phase extract oxygen from air by, under said first conditions, bringing said air (A) into contact with an agent (SfF) constituted by a reversibly oxygen-fixating agent, i.e. an oxygen selective material, such that the oxygen of the air is adsorbed by said agent, and to remove nitrogen under said first conditions, and configured to during a discharging phase release the oxygen from the agent by means of changing said first conditions to said second conditions. The invention also relates to a method for producing oxygen for individual medical purposes.
    Type: Application
    Filed: October 17, 2006
    Publication date: December 3, 2009
    Applicant: Inhalox Technology AB
    Inventor: Oskar Frånberg
  • Publication number: 20090277245
    Abstract: Systems and methods for cooling a chromatographic column is disclosed generally, comprising heating a chromatographic column, supplying fluid into the column via the inlet end of the column at an inlet pressure, decreasing the temperature of the column, thereby causing the fluid in the column to contract, and controlling the fluid in the column such that the rate at which the fluid in the column contracts does not exceed the flow rate of the fluid supplied to the column. In certain embodiments, the rate of change of the volume of the fluid in the column as the column temperature decreases is modeled, and the rate of contraction of the gas in the column is estimated therefrom. In some embodiments, the column temperature and/or inlet pressure are controlled by a programmable chromatographic oven.
    Type: Application
    Filed: May 19, 2009
    Publication date: November 12, 2009
    Inventor: Andrew Tipler
  • Patent number: 7604004
    Abstract: An oxygen separator for separating oxygen from ambient air utilizing a vacuum swing adsorption process has a mass of less than 2.3 kg. A carrier is mountable on a person to support the oxygen separator for ambulatory use.
    Type: Grant
    Filed: April 5, 2006
    Date of Patent: October 20, 2009
    Assignee: Vbox Incorporated
    Inventors: Theodore W. Jagger, Nicholas P. Van Brunt, John A. Kivisto, Perry B. Lonnes
  • Publication number: 20090223369
    Abstract: Disclosed is a gas chromatograph, which comprises a column oven which has a ventilation door disposed in an upper portion thereof and a hydrogen gas sensor installed in an upper region of an internal space thereof. Based on a detection signal from the hydrogen gas sensor, a control section determines a concentration of hydrogen gas contained in a gas within the column oven. If the concentration is equal to or greater than a given threshold value, the control section operates to open the ventilation door while cutting off current to be supplied to a heater, and closing a valve to stop supply of hydrogen gas. Thus, in the event of leakage of hydrogen gas, hydrogen gas accumulated within the column oven can be quickly released outside the column oven to avoid a risk of inflaming.
    Type: Application
    Filed: February 10, 2009
    Publication date: September 10, 2009
    Applicant: SHIMADZU CORPORATION
    Inventors: Hideyuki UEGAKI, Masanao FURUKAWA
  • Publication number: 20090211436
    Abstract: A compliant column sheath assembly for use in a gas chromatograph is provided which includes an open tubular column in the form of a helical coil having a coiled lengt of between about 5 and 15 cm. The sheath assembly further includes an insulating sheath which surrounds the open tubular column and a frame. When incorporated in a gas chromatograph, the compliant column sheath assembly allows samples to be analyzed in about 2 to 10 seconds.
    Type: Application
    Filed: May 19, 2006
    Publication date: August 27, 2009
    Applicant: UNIVERSITY OF DAYTON
    Inventors: Wayne A. Rubey, Richard C. Striebich, Jesse A. Contreras
  • Patent number: 7544233
    Abstract: The aim of the invention is to optimize the analysis of substances separated by gas chromatography with a gas chromatograph, comprising a separating device and a mass spectrometer situated down there from. To this end, a detector that detects the separated substances in a nondestructive manner is placed in-line between the output of the separating device and a controllable inlet valve of the mass spectrometer. An evaluating device situated down from the detector evaluates the detector signals and, based on the evaluation, controls the inlet valve for introducing predeterminable substances into the mass spectrometer.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: June 9, 2009
    Assignee: Siemens Aktiengesellsachaft
    Inventors: Frank Diedrich, Friedhelm Müller
  • Patent number: 7534286
    Abstract: Systems and methods for cooling a chromatographic column is disclosed generally, comprising heating a chromatographic column, supplying fluid into the column via the inlet end of the column at an inlet pressure, decreasing the temperature of the column, thereby causing the fluid in the column to contract, and controlling the fluid in the column such that the rate at which the fluid in the column contracts does not exceed the flow rate of the fluid supplied to the column. In certain embodiments, the rate of change of the volume of the fluid in the column as the column temperature decreases is modeled, and the rate of contraction of the gas in the column is estimated therefrom. In some embodiments, the column temperature and/or inlet pressure are controlled by a programmable chromatographic oven.
    Type: Grant
    Filed: June 14, 2006
    Date of Patent: May 19, 2009
    Assignee: PerkinElmer LAS, Inc.
    Inventor: Andrew Tipler
  • Patent number: 7520920
    Abstract: The present invention discloses a gas chromatograph assembly. In one implementation, the assembly includes a sample injector and a guard column assembly. The guard column assembly includes a guard column connected to and downstream of the sample injector; a jacket with low thermal mass surrounding the guard column; a temperature controlled heater connected to the jacket to control the temperature of the jacket and thereby the temperature of the guard column; and an insulating housing surrounding the jacket. An analytical column is connected to and downstream of the guard column.
    Type: Grant
    Filed: March 6, 2006
    Date of Patent: April 21, 2009
    Assignee: Griffin Analytical Technologies
    Inventors: Mark A. Gregory, Garth E. Patterson, Anthony J. Cochran, Jason L. Springston
  • Publication number: 20090084261
    Abstract: A system for controlling the flow rate into a chromatographic column is disclosed generally comprising communicating a fluid to the column through a transfer line, measuring the inlet pressure, determining the outlet pressure, and adjusting the applied pressure until the inlet and outlet pressures produce a desired flow rate for the transfer line outlet. In certain embodiments, the applied pressure is adjusted by controlling a proportional valve. In some embodiments, the outlet pressure is determined by measuring the pressure drop across the transfer line and calculating the outlet pressure from the measured inlet pressure and the pressure drop.
    Type: Application
    Filed: December 11, 2008
    Publication date: April 2, 2009
    Inventors: Andrew Tipler, Richard G. Edwards
  • Publication number: 20090056540
    Abstract: An apparatus and a method for separating a specified gas from a gas to be treated containing the specified gas comprising at least one ingredient, which comprises allowing the gas to be treated to flow through a column without the use of another gas for transferring the gas to be treated, while keeping the inside of the column packed with a packing material at a reduced pressure. The above apparatus and method can be suitably used for separating a specified gas having a high purity at a low cost.
    Type: Application
    Filed: April 19, 2006
    Publication date: March 5, 2009
    Applicants: Organo Corporation, Japan Atomic Energy Agency
    Inventors: Yoshinori Ono, Takashi Futatsuki, Tetsuya Abe, Sadamitsu Tanzawa, Seiji Hiroki
  • Publication number: 20090000481
    Abstract: Disclosed are systems and methods that include providing a vessel having an inlet and an outlet for communicating a carrier gas through the vessel; determining a differential pressure between the inlet and the outlet for a known flow rate at the outlet; and, determining a unit flow per unit pressure based on a ratio of the flow rate and the differential pressure. In certain embodiments, the flow rate at the outlet is established by controlling the flow rate of the gas. In some embodiments, the methods and systems can include a viscosity in the ratio, determining a flow rate at ambient pressure using a factor based on a ratio of a gas pressure at the output and ambient pressure, and/or, determining a flow rate at ambient temperature using a factor based on a ratio of a temperature at the output and ambient temperature.
    Type: Application
    Filed: September 8, 2008
    Publication date: January 1, 2009
    Inventors: Andrew Tipler, Nell T. Plant
  • Patent number: 7468095
    Abstract: A system for controlling the flow rate into a chromatographic column is disclosed generally comprising communicating a fluid to the column through a transfer line, measuring the transfer line inlet pressure, determining the transfer line outlet pressure, and adjusting the applied pressure until the inlet and outlet pressures produce a desired flow rate for the transfer line outlet. In certain embodiments, the applied pressure is adjusted by controlling a proportional valve. In some embodiments, the outlet pressure is determined by measuring the pressure difference across the transfer line and calculating the transfer line outlet pressure from the measured inlet pressure and the pressure difference.
    Type: Grant
    Filed: May 11, 2006
    Date of Patent: December 23, 2008
    Assignee: PerkinElmer LAS, Inc.
    Inventors: Andrew Tipler, Richard G Edwards
  • Patent number: 7422625
    Abstract: Disclosed are systems and methods that include providing a vessel having an inlet and an outlet for communicating a carrier gas through the vessel; determining a differential pressure between the inlet and the outlet for a known flow rate at the outlet; and, determining a unit flow per unit pressure based on a ratio of the flow rate and the differential pressure. In certain embodiments, the flow rate at the outlet is established by controlling the flow rate of the gas. In some embodiments, the methods and systems can include a viscosity in the ratio, determining a flow rate at ambient pressure using a factor based on a ratio of a gas pressure at the output and ambient pressure, and/or, determining a flow rate at ambient temperature using a factor based on a ratio of a temperature at the output and ambient temperature.
    Type: Grant
    Filed: September 10, 2007
    Date of Patent: September 9, 2008
    Assignee: PerkinElmer LAS, Inc.
    Inventors: Andrew Tipler, Neil T. Plant
  • Publication number: 20080184892
    Abstract: The present invention generally relates to electrochemical systems for producing hydrogen and/or power. Various aspects of the invention are directed to reactor designs for producing hydrogen and/or power from a fuel and water, conducting ceramics and other materials for such systems, including mixed ionically and electrically conducting ceramics which can be used for hydrogen gas generation, control systems for such systems, and methods of operating such systems.
    Type: Application
    Filed: March 29, 2007
    Publication date: August 7, 2008
    Applicant: CTP Hydrogen Corporation
    Inventors: Reinder J. Boersma, Scott C. Rackey, Jack A. Shindle