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  • Integrated optical circulator apparatus, method, and applications
    Patent number: 9979160
    Abstract: An optical circulator is a device that routes optical pulses from port to port in a predetermined manner, e.g. in a 3-port optical circulator, optical pulses entering port 1 are routed out of port 2, while optical pulses entering port 2 exit out of port 3 and optical pulses fed into port 3 exit out of port 3. Currently such an optical circulator is made of discrete components such as magnetooptic garnets, rare-earth magnets and optical polarizers that are packaged together with fiber optic elements. Disclosed herein is a different kind of optical circulator that is monolithically integrated on a single semiconductor substrate and that is applicable for the routing of optical pulses. The embodied invention will enable photonic integrated circuits to incorporate on-chip optical circulator functionality thereby allowing much more complex optical designs to be implemented monolithically.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: May 22, 2018
    Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Demetrios Christodoulides, Patrick L. LiKamWa, Parinaz Aleahmad, Ramy El-Ganainy
  • Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
    Patent number: 8101431
    Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: January 24, 2012
    Assignee: Board of Regents, The University of Texas System
    Inventors: John T. McDevitt, Karri L. Ballard, Pierre N. Floriano, Nick J. Christodoulides, Dean Neikirk, Eric Anslyn, Jason Shear
  • Methods and compositions related to determination and use of white blood cell counts
    Patent number: 8377398
    Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: February 19, 2013
    Assignees: The Board of Regents of The University of Texas System, LabNow, Inc.
    Inventors: John T. McDevitt, Nicolaos J. Christodoulides, Pierre N. Floriano, Gary N. Douglas, Patrick E. Rogers
  • Particle on membrane assay system
    Patent number: 7781226
    Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: August 24, 2010
    Assignee: The Board of Regents of the University of Texas System
    Inventors: John T. McDevitt, Nick Christodoulides, Pierre Floriano, Karri L. Ballard, Bruce Bernard, Glenn Simmons
  • Communication method and apparatus
    Patent number: 6665361
    Abstract: A set of formats and protocols is proposed for a satellite communications system. In these formats, a pilot signal (PS) is inserted after every 25 or 29 data symbols. The formats consist of SCPC frames (F) which may contain either data (D) and in-band signalling information (SU), or only signalling information (SU). In either case, the contents of each frame (F) are error-correction coded before transmission with the same coding rate. Each data frame (F) carries the data content of an integral number of input user data frames (M), each of which comprises four subframes. Different symbol transmission rates are used for different input data rates, the symbol transmission rates being selected so that their different synchronizing clock rates can easily be obtained from a common clock. Data bursts may be preceded by a constant power level preamble (P). The formats and protocols satisfy the requirements of a high data rate satellite communications system.
    Type: Grant
    Filed: March 4, 1999
    Date of Patent: December 16, 2003
    Assignee: Inmarsat, Ltd.
    Inventors: Louis Mimis Christodoulides, Howard Ray Feldman, Eyal Trachtman, Siu Wah Wong, Hok Shuen Wong
  • Method and system for the analysis of saliva using a sensor array
    Patent number: 7651868
    Abstract: A system for the rapid characterization of analytes in saliva. In one embodiment, a system for detecting analytes includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member, in which a plurality of cavities may be formed. A series of chemically sensitive particles, in one embodiment, are positioned within the cavities. The particles may produce a signal when a receptor, coupled to the particle, interacts with the cardiovascular risk factor analyte and the particle-analyte complex is visualized using a visualization reagent. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized. In an embodiment, each cavity of the plurality of cavities is designed to capture and contain a specific size particle. Flexible projections may be positioned over each of the cavities to provide retention of the particles in the cavities.
    Type: Grant
    Filed: December 13, 2004
    Date of Patent: January 26, 2010
    Assignee: The Board of Regents of The University of Texas System
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk, Nick J. Christodoulides
  • Communication method and apparatus
    Patent number: 7266097
    Abstract: A set of formats and protocols is proposed for a satellite communications system. In these formats, a pilot signal (PS) is inserted after every 25 or 29 data symbols. The formats consist of SCPC frames (F) which may contain either data (D) and in-band signaling information (SU), or only signaling information (SU). In either case, the contents of each frame (F) are error-correction coded before transmission with the same coding rate. Each data frame (F) carries the data content of an integral number of input user data frames (M), each of which comprises four subframes. Different symbol transmission rates are used for different input data rates, the symbol transmission rates being selected so that their different synchronizing clock rates can easily be obtained from a common clock. Data bursts may be preceded by a constant power level preamble (P). The formats and protocols satisfy the requirements of a high data rate satellite communications system.
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: September 4, 2007
    Assignee: Inmarsat Global Limited
    Inventors: Louis Mimis Christodoulides, Howard Ray Feldman, Eyal Trachtman, Siu Wah Wong, Hok Shuen Wong
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