Search Patents
  • Electrostatic aerosol concentrator
    Patent number: 8663374
    Abstract: An apparatus for concentrating aerosol particles can include: a sample air inlet; an enriched aerosol outlet; an aerosol lean outlet; a flow path connecting the air inlet and aerosol rich and aerosol lean outlets; and a plurality of alternately energized and grounded electrode pairs along the flow path. The aerosol rich outlet can be in fluid communication with an aerosol particle capture device. The apparatus can include a sheath air inlet providing a flow of aerosol free air over surfaces of the alternately energized and grounded electrode pairs. The apparatus can include an elongate focusing chamber having a cylindrical shape containing the alternately energized and grounded electrode pairs that are configured as circular rings. The apparatus can include one or more structures configured to impart tangential, spiral or helical flow to a stream entering through the sample air inlet.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: March 4, 2014
    Assignee: CFD Research Corporation
    Inventors: Kapil Pant, Shivshankar Sundaram, Yi Wang
  • Single-circuit fuel injector for gas turbine combustors
    Patent number: 6543235
    Abstract: A single circuit fuel injector apparatus having a bifurcated recirculation zone is provided. The single circuit injector includes an injector tip having an aft facing tapered surface which is communicated with a plurality of fuel injector ports. A radially inward tapered conical air splitter directs sweep air over the tapered injector tip. An air blast atomizer filmer lip is disposed concentrically outward from the tapered tip. In a low power operating mode, fuel exiting the fuel injector ports is entrained within a centralized sweep air stream. In a high power operating mode, the majority of the fuel exiting the fuel injection ports has sufficient momentum to carry it across the sweep air stream so that it falls upon the main fuel filmer lip and is entrained in an outer main air stream.
    Type: Grant
    Filed: August 8, 2001
    Date of Patent: April 8, 2003
    Assignee: CFD Research Corporation
    Inventors: David S. Crocker, David L. Black
  • Alcohol based biofuel cell
    Patent number: 11139500
    Abstract: An anode can include: an electrode substrate; a first region of the substrate having a catalyst composition located thereon, wherein the catalyst composition includes an inorganic or metallic catalyst; and a second region of the substrate having an enzyme composition located thereon, wherein the combination of the catalyst composition and enzyme composition converts a fuel reagent to carbon dioxide at neutral pH. The first region and second region can be separate regions. The catalyst of the catalyst composition can include gold nanoparticles. The catalyst can include an inorganic or metallic catalyst selected from vanadium oxide, titanium (III) chloride, Pd(OAc)2, MnO, zeolite, alumina, graphitic carbon, palladium, platinum, gold, ruthenium, rhodium, iridium, or combinations thereof. The catalyst can be nanoparticle, nanorod, nanodot, or combination thereof. The catalyst can have sizes that range from about 10 to 20 nm.
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: October 5, 2021
    Assignee: CFD Research Corporation
    Inventors: Mary Arugula, Erica Wagner Pinchon, Sameer Singhal
  • Method and apparatus for separating particles by dielectrophoresis
    Patent number: 8778160
    Abstract: Particle separation apparatus separate particles and particle populations using dielectrophoretic (DEP) forces generated by one or more pairs of electrically coupled electrodes separated by a gap. Particles suspended in a fluid are separated by DEP forces generated by the at least one electrode pair at the gap as they travel over a separation zone comprising the electrode pair. Selected particles are deflected relative to the flow of incoming particles by DEP forces that are affected by controlling applied potential, gap width, and the angle linear gaps with respect to fluid flow. The gap between an electrode pair may be a single, linear gap of constant gap, a single linear gap having variable width, or a be in the form of two or more linear gaps having constant or variable gap width having different angles with respect to one another and to the flow.
    Type: Grant
    Filed: July 26, 2011
    Date of Patent: July 15, 2014
    Assignee: CFD Research Corporation
    Inventors: Kapil Pant, Yi Wang, Ketan Bhatt, Balabhasker Prabhakarpandian
  • Hematin modified bilirubin oxidase cathode
    Patent number: 11127966
    Abstract: A cathode can include: an electrode substrate; a porphyrin precursor attached to the substrate; and an enzyme coupled to the electrode substrate to be associated with the porphyrin precursor, the enzyme reduces oxygen. The cathode can include a conductive material associated with the porphyrin precursor and/or the enzyme. The cathode can include 1-pyrenebutanoic acid, succinimidyl ester (PBSE) associated with the porphyrin precursor and/or the enzyme and/or the conductive material. The cathode can include 2,5-dimethyl-1-phenyl-1H-pyrrole-3-carbaldehyde (DMY-Carb) associated with the 1-pyrenebutanoic acid, succinimidyl ester (PBSE) and/or the porphyrin precursor and/or the enzyme and/or the conductive material. The porphyrin precursor is attached to the substrate through covalent coupling.
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: September 21, 2021
    Assignee: CFD Research Corporation
    Inventors: Mary Arugula, Erica Wagner Pinchon, Sameer Singhal, Yevgenia Ulyanova
  • Nonlinear passive hearing protection device and method
    Patent number: 11285046
    Abstract: A passive non-linear earplug can include: a tapered body having a channel extending from a wider distal end to a narrower proximal end, the tapered body having shape memory and size adapted for being received into an ear canal of a human subject; and a disk attached to the wider distal end of the tapered body, the disk having one or more holes aligned with the channel. A structural tube can be located in the channel. A handle can be attached to the tapered body and/or disk. An annular member can be coupled to the disk opposite of the tapered body, the annular member having an aperture that at least partially aligns with the channel. A tube member can be coupled to the disk opposite of the tapered body. The earplug can attenuate loud sounds while allowing normal sounds to be heard, which provides for the non-linearity.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: March 29, 2022
    Assignee: CFD Research Corporation
    Inventors: Vincent Johannes Harrand, David Keith Sedberry, Jr., Phillip Edward Whitley, Xiangguang Gary Tan, Andrzej Przekwas
  • Non-lethal weapons modular human surrogate testing device and method
    Patent number: 11600203
    Abstract: A modular surrogate can include: a body having an external body surface with an anatomical shape, wherein the body includes an internal chamber with at least one port formed in the body extending inwardly; at least one anatomical module having an external module portion and a module stem coupled thereto, the module stem being received into a corresponding module port of the at least one port, the external module portion having an external module surface with an anatomical shape, the external body surface matches with the external module surface to provide a continuous anatomical shape; at least one sensor located in the at least one anatomical module; and at least one controller, wherein when the at least one anatomical module is coupled with the body, the at least one sensor is capable of being operably coupled with the at least one controller.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: March 7, 2023
    Assignee: CFD Research Corporation
    Inventors: David Keith Sedberry, Vincent J. Harrand, Phillip E. Whitley, Andrzej Przekwas
  • System and method for reconstruction of explosion blast and blast loading on humans using pressure sensor data
    Patent number: 10983020
    Abstract: A system for reconstruction of an explosion blast loading on a subject can include at least two pressure sensors and a computing system configured to: receive sensor data from the at least two pressure sensors, the sensor data being generated in response to an explosion blast wave; compute an explosion location and explosive charge mass of an explosive that caused the explosion blast wave based on the sensor data; and compute explosion blast loading on a subject from the explosion location and explosive charge mass. The pressure sensors can be configured as wearable pressure sensors or on equipment. The computing of the explosion location and explosive charge mass includes processing the sensor data through an inverse problem solver (IPS); and/or the computing of the explosion blast loading on the subject includes simulating the explosion blast wave with a forward problem solver (FPS).
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: April 20, 2021
    Assignees: CFD Research Corporation, The Government of the United States, as represented by the Secretary of the Army
    Inventors: Zhijian Chen, Andrzej Przekwas, Vincent Harrand, Raj K. Gupta
  • Double lumen catheter
    Patent number: 6409700
    Abstract: Blood is withdrawn from a vein by a double lumen catheter that has an elongated tube with unitary outer walls. A longitudinal planar septum divides the interior of the tube into an inlet lumen and a longer return lumen. The inlet lumen extends from a proximal end of the tube to an end terminating in a distally forward facing aperture. The return lumen extends contiguously with the inlet lumen from the proximal end of the tube to an end terminating in a distally forward facing aperture spaced in the longitudinal direction distally forward of the inlet lumen aperture. A diverting structure extends from an outer wall of the return lumen distally forward of the aperture of the inlet lumen. The diverting structure diverts flow of treated fluid discharged from the return lumen away from the distally forward facing aperture of the inlet lumen. The blood withdrawn via the catheter is circulated for treatment in a blood purification system.
    Type: Grant
    Filed: March 22, 1999
    Date of Patent: June 25, 2002
    Assignee: CFD Research Corporation
    Inventors: John M. Siegel, Jr., Vinod B. Makhijani, Ming Lei, Jagannath Raghavan
  • Fluorine-based cathode materials for thermal batteries
    Patent number: 10446853
    Abstract: A thermal battery can include: an anode of lithium alloy; a metal-fluoride cathode having Ni; and an electrolyte composition in contact with the anode and cathode. A thermal battery can also include: an anode of lithium alloy; a metal-fluoride cathode having an oxide selected from V2O5 or LiVO3; and an electrolyte composition in contact with the anode and cathode. In one aspect, a metal of the metal fluoride cathode includes Ni, Fe, V, Cr, Mn, Co, or mixture thereof. In one aspect, the metal-fluoride cathode includes NiF2, FeF3, VF3, CrF3, MnF3, CoF3, or a mixture thereof. A method of providing electricity can include: providing an electronic device having a thermal battery with a metal-fluoride cathode having Ni and/or having an oxide selected from V2O5 or LiVO3; and discharging the thermal battery to provide electricity.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: October 15, 2019
    Assignee: CFD Research Corporation
    Inventors: Pyoungho Choi, Sameer Singhal, Joe Don Edington
  • Piloted airblast lean direct fuel injector
    Patent number: 6272840
    Abstract: A gas turbine fuel injection system of the lean direct injector type designed to reduce nitrous oxide (NOx) emissions is provided. The configuration includes a pilot fuel injector for injecting a pilot fuel stream, and a pilot swirler for providing a swirling pilot air stream to atomize and entrain the pilot fuel stream. A main airblast fuel injector is located concentrically about the pilot fuel injector, for injecting a main fuel stream concentrically about the pilot fuel stream. Inner and outer main swirlers provide a swirling main air stream to atomize and entrain the main fuel stream. An air splitter is located between the pilot swirler and the main swirler. The air splitter is so arranged and constructed as to divide the pilot air stream exiting the pilot swirler and the air splitter, from the main air stream exiting the inner main swirler, whereby a bifurcated recirculation zone is created.
    Type: Grant
    Filed: August 29, 2000
    Date of Patent: August 14, 2001
    Assignee: CFD Research Corporation
    Inventors: David S. Crocker, Daniel A. Nickolaus, Clifford E. Smith
  • FLUORINE-BASED CATHODE MATERIALS FOR THERMAL BATTERIES
    Publication number: 20200083543
    Abstract: A thermal battery can include: an anode of lithium alloy; a metal-fluoride cathode having Ni; and an electrolyte composition in contact with the anode and cathode. The electrolyte composition can be a tertiary electrolyte composition of LiF—LiCl—Li2SO4. A thermal battery can also include: an anode of lithium alloy; a metal-fluoride cathode having an oxide selected from V2O5 or LiVO3; and an electrolyte composition in contact with the anode and cathode. In one aspect, a metal of the metal fluoride cathode includes Ni, Fe, V, Cr, Mn, Co, or mixture thereof. In one aspect, the metal-fluoride cathode includes NiF2, FeF3, VF3, CrF3, MnF3, CoF3, or a mixture thereof. A method of providing electricity can include: providing an electronic device having a thermal battery with a metal-fluoride cathode having Ni and/or having an oxide selected from V2O5 or LiVO3; and discharging the thermal battery to provide electricity.
    Type: Application
    Filed: July 3, 2019
    Publication date: March 12, 2020
    Applicant: CFD Research Corporation
    Inventors: Pyoungho CHOI, Sameer Singhal, Joe Don Edington
  • Methods and compositions for selectively inhibiting pathogenic microbes
    Patent number: 11180452
    Abstract: A method of selectively inhibiting pathogenic microbes includes: providing a compound that is functional as a selective antimicrobial having a structure of Formula 1, or derivative thereof, salt thereof, or stereoisomer thereof, or having any chirality at any chiral center, or tautomer, polymorph, solvate, or combination thereof; and contacting a pathogenic microbe with the compound such that the pathogenic microbe is selectively inhibited; wherein: ring A is a cycloalkyl, heterocycloalkyl, aryl, heteroaryl, or polycycle combination thereof; X is S, SO, or SO2; Y is a linker or bond; Z is CH, CR2, or N; Z1 is C or N to form an imidazopyridine; each Z2, Z3, or Z4 is independently CH, CR2, or N; each Z5 or Z6 is C or CH; each R1, R2, R3 and/or R4 is independently a substituent; m is 0, 1, 2, 3, or 4; and n is zero or a positive integer.
    Type: Grant
    Filed: June 17, 2020
    Date of Patent: November 23, 2021
    Assignees: CFD Research Corporation, The Board of Regents of the University of Oklahoma
    Inventors: Anuj Singhal, Robert H. Cichewicz, Lin Du, JianLan You, Hanumantha Rao Paritala, Abigail Grace Edwards
  • Electrostatic Aerosol Concentrator
    Publication number: 20110277632
    Abstract: Disclosed is an electrostatic aerosol concentrator for the concentration of aerosol particles and their collection for subsequent analysis. The concentrator comprises an airflow chamber that includes alternately energized and grounded electrode elements that work in concert to impart radial inward motion to charged aerosol particles and focusing them toward an enriched aerosol outlet. If desired, filtered air inlets may be used to provide a sheath of aerosol-free air along the chamber periphery and prevent deposition of particles onto electrode surfaces. Aerosol particles entering the airflow chamber may carry a positive or negative charge naturally, or a charge may be induced on the particles using a charging section located upstream of the aerosol inlet. Natural or induced charges on the aerosol particles may be used to selectively concentrate subpopulations of aerosol particles from a mixture of particles.
    Type: Application
    Filed: July 31, 2007
    Publication date: November 17, 2011
    Applicant: CFD RESEARCH CORPORATION
    Inventors: Kapil Pant, Shivshakar Sundaram, Yi Wang
  • ELECTROSTATIC AEROSOL CONCENTRATOR
    Publication number: 20130192462
    Abstract: Disclosed is an electrostatic aerosol concentrator for the concentration of aerosol particles and their collection for subsequent analysis. The concentrator comprises an airflow chamber that includes alternately energized and grounded electrode elements that work in concert to impart radial inward motion to charged aerosol particles and focusing them toward an enriched aerosol outlet. If desired, filtered air inlets may be used to provide a sheath of aerosol-free air along the chamber periphery and prevent deposition of particles onto electrode surfaces. Aerosol particles entering the airflow chamber may carry a positive or negative charge naturally, or a charge may be induced on the particles using a charging section located upstream of the aerosol inlet. Natural or induced charges on the aerosol particles may be used to selectively concentrate subpopulations of aerosol particles from a mixture of particles.
    Type: Application
    Filed: August 3, 2012
    Publication date: August 1, 2013
    Applicant: CFD RESEARCH CORPORATION
    Inventors: Kapil Pant, Shivshankar Sundaram, Yi Wang
  • System and method for model-based calculation of blast exposure
    Patent number: 11145418
    Abstract: A method of calculating blast injury metrics in a weapon training/IED blast scene can include: reconstructing topological layout of the scene having at least one real subject and a blast source; obtaining anthropometric and posture data for each real subject; obtaining anatomical soldier model for each real subject; identifying real position of at least one real pressure sensor on each soldier during a blast; positioning a virtual sensor on each anatomical soldier model to correspond with real pressure sensor on the real subject; calculating weapon signature of the blast source, the weapon signature including pressure versus time for a blast from the blast source; generating simulated pressure traces on each anatomical soldier model at east virtual pressure sensor; calculating blast injury metrics for the at least one real subject; and generating a report that includes the blast injury metrics for the at least one real subject.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: October 12, 2021
    Assignees: CFD RESEARCH CORPORATION, The Government of The United States, as represented by the Secretary of the Army
    Inventors: Andrzej Przekwas, Harsha T. Garimella, Timothy Zehnbauer, Zhijian Chen, Vincent Harrand, Raj Kumar Gupta, Gary Kamimori, Walter Carr
  • SYNTHETIC MICROFLUIDIC SYSTEMS FOR HYPOXIA
    Publication number: 20140255970
    Abstract: A cell culture device can include: an internal chamber configured for an internal cell culture that has at least one port coupled to a perfusion modulating device capable of modulating perfusion in the internal chamber; at least one fluid channel bordering the internal chamber that is configured for a channel cell culture that has at least one port coupled to a perfusion modulating device capable of modulating perfusion in the fluid channel; and a wall separating the internal chamber and at least one fluid channel having gaps that fluidly couple the internal chamber with the at least one fluid channel, wherein the perfusion modulating device causes reduced fluid flow. The internal chamber can include a first cell type and the at least one fluid channel includes a second cell type. The first cell type has an ischemic zone in the middle, a non-ischemic zone adjacent with the at least one fluid channel, and a border zone between the ischemic zone and non-ischemic zone.
    Type: Application
    Filed: March 10, 2014
    Publication date: September 11, 2014
    Applicant: CFD Research Corporation
    Inventors: Balabhaskar Prabhakarpandian, Kapil Pant
  • Adaptive Refinement Tools for Tetrahedral Unstructured Grids
    Publication number: 20080312887
    Abstract: An exemplary embodiment providing one or more improvements includes software which is robust, efficient, and has a very fast run time for user directed grid enrichment and flow solution adaptive grid refinement. All user selectable options (e.g., the choice of functions, the choice of thresholds, etc.), other than a pre-marked cell list, can be entered on the command line. The ease of application is an asset for flow physics research and preliminary design CFD analysis where fast grid modification is often needed to deal with unanticipated development of flow details.
    Type: Application
    Filed: June 13, 2008
    Publication date: December 18, 2008
    Applicant: U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration
    Inventors: S. Paul Pao, Khaled S. Abdol-Hamid
  • Adaptive refinement tools for tetrahedral unstructured grids
    Patent number: 7991595
    Abstract: An exemplary embodiment providing one or more improvements includes software which is robust, efficient, and has a very fast run time for user directed grid enrichment and flow solution adaptive grid refinement. All user selectable options (e.g., the choice of functions, the choice of thresholds, etc.), other than a pre-marked cell list, can be entered on the command line. The ease of application is an asset for flow physics research and preliminary design CFD analysis where fast grid modification is often needed to deal with unanticipated development of flow details.
    Type: Grant
    Filed: June 13, 2008
    Date of Patent: August 2, 2011
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventors: S. Paul Pao, Khaled S. Abdol-Hamid
  • PHYSICAL DEFORMABLE LUNG PHANTOM WITH SUBJECT SPECIFIC ELASTICITY
    Publication number: 20170018205
    Abstract: A system and method to integrate computational fluid dynamics (CFD) and radiotherapy data for accurate simulation of spatio-temporal flow and deformation in real human lung is presented. The method utilizes a mathematical formulation that fuses the CFD predictions of lung displacement with the corresponding radiotherapy data using the theory of Tikhonov regularization.
    Type: Application
    Filed: July 13, 2016
    Publication date: January 19, 2017
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Anand P. SANTHANAM, Olusegun ILEGBUSI
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