Search Patents
  • VIRUS VACCINES
    Publication number: 20020071848
    Abstract: Improved mammalian virus vaccines are combinations that contain an immunogenic amount of inactivated virus, such as influenza virus, Herpes varicella virus, measles virus, Epstein Barr virus, respiratory syncytial virus, parainfluenza 3, Herpes simplex type 1 virus, and Herpes simplex type 2 virus, and an immunogenic amount of a purified recombinant envelope protein from the virus, or a fragment or precursor of the protein. Alternatively, they contain either inactivated virus and/or envelope protein antigens and an adjuvant such as granulocyte-microphage colony stimulating factor. One embodiment of an influenza vaccine is prepared by combining inactivated virus, preferably three strains of the virus, and hemagglutinin, preferably a combination of respective hemagglutinins for each of the three strains present.
    Type: Application
    Filed: January 22, 1999
    Publication date: June 13, 2002
    Inventors: GALE EUGENE SMITH, BETHANIE E. WILKINSON, ANDREI I. VOZNESENSKY, FRANKLIN VOLVOVITZ, CRAIG S. HACKETT
  • HOST TARGETED INHIBITORS OF DENGUE VIRUS AND OTHER VIRUSES
    Publication number: 20150166532
    Abstract: Novel antiviral compounds of Formulae (I)-(III) are provided: (I) (II) (III) The inventive compounds, pharmaceutical compositions thereof, and kits including the inventive compounds are useful for the prevention and treatment of infectious diseases caused by viruses, for example, by Flaviviridae virus (e.g., Dengue virus (DENY)), Kunjin virus, Japanese encephalitis virus, vesicular stomatitis virus (VSV), herpes simplex virus 1 (HSV-1), human cytomegalovirus (HCMV), poliovirus, Junin virus, Ebola virus, Marburg virus (MARV), Lassa fever virus (LASV), Venezuelan equine encephalitis virus (VEEV), or Rift Valley Fever virus (RVFV).
    Type: Application
    Filed: March 15, 2013
    Publication date: June 18, 2015
    Inventors: Nathanael Gray, Priscilla Yang, Qingsong Liu, Mélissanne de Wispelaere
  • ELECTRONIC DEVICE WITH VIRUS PREVENTION FUNCTION AND VIRUS PREVENTION METHOD THEREOF
    Publication number: 20130312100
    Abstract: In a virus prevention method of an electronic device, executable files that are being installed in the electronic device are compared with the virus characteristics in virus database of the electronic device. The electronic device communicates with a server through a network, and a virus database and a suspected virus database of the server are accessed when one or more suspected files are determined. The one or more suspected files are compared with virus characteristics of virus samples in the virus database and non-viral characteristic of non-virus samples in the suspected virus database of the server, so as to determine whether the one or more suspected files are virus files. The determined one or more virus files intruded in the executed files are deleted.
    Type: Application
    Filed: May 15, 2013
    Publication date: November 21, 2013
    Applicants: HON HAI PRECISION INDUSTRY CO., LTD., FU TAI HUA INDUSTRY (SHENZHEN) CO., LTD.
    Inventor: PENG WANG
  • Virus vaccines
    Patent number: 5976552
    Abstract: Improved mammalian virus vaccines are combinations that contain an immunogenic amount of inactivated virus, such as influenza virus, Herpes varicella virus, measles virus, Epstein Barr virus, respiratory syncytial virus, parainfluenza 3, Herpes simplex type 1 virus, and Herpes simplex type 2 virus, and an immunogenic amount of a purified recombinant envelope protein from the virus, or a fragment or precursor of the protein. Alternatively, they contain either inactivated virus and/or envelope protein antigens and an adjuvant such as granulocyte-microphage colony stimulating factor. One embodiment of an influenza vaccine is prepared by combining inactivated virus, preferably three strains of the virus, and hemagglutinin, preferably a combination of respective hemagglutinins for each of the three strains present.
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: November 2, 1999
    Assignee: Protein Sciences Corporation
    Inventor: Franklin Volvovitz
  • METHOD FOR ISOLATING HEPATITIS A VIRUS OR SPRING VIREMIA OF CARP VIRUS
    Publication number: 20130244221
    Abstract: A method for isolating Hepatitis A virus or Spring viremia of Carp virus. A virus probe is prepared by linking a magnetic bead-conjugated Protein G with an anti-HAV (Hepatitis A Virus) antibody or an anti-rhabdovirus antibody. The virus probe is contacted with a sample to be analyzed to form a virus probe-virus complex. The virus probe-virus complex is then isolated. It may specifically isolate Hepatitis A virus or Spring viremia of Carp virus from a sample mixed viruses.
    Type: Application
    Filed: October 12, 2012
    Publication date: September 19, 2013
    Applicant: INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY
    Inventors: Du Woon Kim, Hee Min Lee, Se Young Cho, Sang Mu Ko, Kyung Seo Oh, Joseph Kwon, Jong Soon Choi
  • System and method for identifying a macro virus family using a macro virus definitions database
    Patent number: 7210041
    Abstract: A macro virus definitions database is maintained and includes a set of indices and associated macro virus definition data files. One or more of the macro virus definition data files are referenced by the associated index. Each macro virus definition data file defines macro virus attributes for known macro viruses. The sets of the indices and the macro virus definition data files are organized according to macro virus families. One or more strings stored in a suspect file are compared to the macro virus attributes defined in the one or more macro virus definition data files for each macro virus family in the macro virus definitions database. The macro virus family to which the suspect file belongs is determined from the indices for each of the macro virus definition data files at least partially containing the suspect file.
    Type: Grant
    Filed: April 30, 2001
    Date of Patent: April 24, 2007
    Assignee: McAfee, Inc.
    Inventors: Dmitry O. Gryaznov, Viatcheslav Peternev, Igor Muttik
  • HOST TARGETED INHIBITORS OF DENGUE VIRUS AND OTHER VIRUSES
    Publication number: 20190292178
    Abstract: Novel antiviral compounds of Formulae (I)-(III) are provided: The inventive compounds, pharmaceutical compositions thereof, and kits including the inventive compounds are useful for the prevention and treatment of infectious diseases caused by viruses, for example, by Flaviviridae virus (e.g., Dengue virus (DENV)), Kunjin virus, Japanese encephalitis virus, vesicular stomatitis virus (VSV), herpes simplex virus 1 (HSV-1), human cytomegalovirus (HCMV), poliovirus, Junin virus, Ebola virus, Marburg virus (MARV), Lassa fever virus (LASV), Venezuelan equine encephalitis virus (VEEV), or Rift Valley Fever virus (RVFV).
    Type: Application
    Filed: January 26, 2018
    Publication date: September 26, 2019
    Applicants: Dana-Farber Cancer Institute, Inc., President and Fellows of Harvard College
    Inventors: Nathanael S. Gray, Priscilla L. Yang, Qingsong Liu, Mélissanne de Wispelaere
  • COMPOSITION FOR TREATMENT, INHIBITION AND ATTENUATION OF VIRUS
    Publication number: 20150238522
    Abstract: The embodiments herein relate to a therapeutically active composition for the treatment, inhibition or attenuation of a virus. The composition comprises an effective amount of a sulfur containing compound along with one or more pharmaceutically acceptable carriers or excipients. The sulfur containing compound impairs a disulfide bond of a plurality of virus. The plurality of virus includes Ebola virus, herpes virus, dengue virus, smallpox virus, measles virus, mumps rubella virus, HIV (human immunodeficiency virus), Lassa fever virus and yellow fever virus, and even cancer, solid tumors, especially the fibrosarcoma tumor. The sulfur containing compound is sodium thiosulfate (Na2S2O3) (“STS”). The composition is given orally, intravenously, inhalation, intravesical, vaginal, rectal, sublingual, ophthalmic, or topical.
    Type: Application
    Filed: May 8, 2015
    Publication date: August 27, 2015
    Inventor: Frederick J. Sawaya
  • VIRUS CO-PROCESSOR INSTRUCTIONS AND METHODS FOR USING SUCH
    Publication number: 20140351937
    Abstract: Circuits and methods for detecting, identifying and/or removing undesired content are provided. According to one embodiment, a method for virus processing is provided. A virus signature file that includes multiple virus signatures capable of detecting and identifying a variety of known viruses is downloaded by a general purpose processor. It is determined by the general purpose processor whether a virus co-processor is coupled to the general purpose processor. When the virus co-processor is determined to be coupled to the general purpose processor, then it is further determined by the general purpose processor which virus signatures are supported by the virus co-processor (“CP-supported virus signatures”). The CP-supported virus signatures are transferred to a memory associated with the virus co-processor. The virus co-processor is directed by the general purpose processor to perform a virus scan based on the supported virus signatures.
    Type: Application
    Filed: August 8, 2014
    Publication date: November 27, 2014
    Applicant: Fortinet, Inc.
    Inventors: Lin Huang, Xu Zhou, Michael Xie
  • HOST TARGETED INHIBITORS OF DENGUE VIRUS AND OTHER VIRUSES
    Publication number: 20180265507
    Abstract: Novel antiviral compounds of Formulae (I)-(III) are provided: The inventive compounds, pharmaceutical compositions thereof, and kits including the inventive compounds are useful for the prevention and treatment of infectious diseases caused by viruses, for example, by Flaviviridae virus (e.g., Dengue virus (DENV)), Kunjin virus, Japanese encephalitis virus, vesicular stomatitis virus (VSV), herpes simplex virus 1 (HSV-1), human cytomegalovirus (HCMV), poliovirus, Junin virus, Ebola virus, Marburg virus (MARV), Lassa fever virus (LASV), Venezuelan equine encephalitis virus (VEEV), or Rift Valley Fever virus (RVFV).
    Type: Application
    Filed: January 26, 2018
    Publication date: September 20, 2018
    Applicants: Dana-Farber Cancer Institute, Inc., President and Fellows of Harvard College
    Inventors: Nathanael S. Gray, Priscilla L. Yang, Qingsong Liu, Mélissanne de Wispelaere
  • Host targeted inhibitors of dengue virus and other viruses
    Patent number: 9879003
    Abstract: Novel antiviral compounds of Formulae (I)-(III) are provided: (I) (II) (III) The inventive compounds, pharmaceutical compositions thereof, and kits including the inventive compounds are useful for the prevention and treatment of infectious diseases caused by viruses, for example, by Flaviviridae virus (e.g., Dengue virus (DENY)), Kunjin virus, Japanese encephalitis virus, vesicular stomatitis virus (VSV), herpes simplex virus 1 (HSV-1), human cytomegalovirus (HCMV), poliovirus, Junin virus, Ebola virus, Marburg virus (MARV), Lassa fever virus (LASV), Venezuelan equine encephalitis virus (VEEV), or Rift Valley Fever virus (RVFV).
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: January 30, 2018
    Assignees: Dana-Farber Cancer Institute, Inc., President and Fellows of Harvard College
    Inventors: Nathanael Gray, Priscilla Yang, Qingsong Liu, Mélissanne de Wispelaere
  • Method and system for generating and using a virus free file certificate
    Patent number: 6928550
    Abstract: A method and system are disclosed for generating and using a virus-free file certificate. The method, for use in a virus-free certificate authority (102), includes the steps of: receiving (300) a virus-free certificate request for a file from a server (101) or a client (100) system; determining (301) whether the file is virus-free or not; if the file is declared virus-free by the virus-free certificate authority (102): generating (303, 304) a virus-free certificate (200) including a file signature (207) for certifying that said file is declared virus-free by the virus-free certificate authority (102); sending (306) back in response to the virus-free certificate request the virus-free certificate (200).
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: August 9, 2005
    Assignee: International Business Machines Corporation
    Inventors: Jean-François Le Pennec, Olivier Hericourt, Jacques Fieschi
  • System and method for computer network virus exclusion
    Publication number: 20020199116
    Abstract: A method of network virus exclusion comprises identifying client computers that are at least one of virus susceptible and virus infected, and isolating those virus susceptible client computers and virus infected client computers from authorized communication with a server of the network. A virus exclusion network system comprises a client computer including a virus protector and a network server including a virus monitor. The virus monitor is configured for preventing an authorized network connection between the client computer and the server when the client computer fails to produce at least one of a report an up-to-date virus scan of the client computer and a report of enablement of the virus protector of the client computer.
    Type: Application
    Filed: June 25, 2001
    Publication date: December 26, 2002
    Inventors: Keith Hoene, William I. Herrmann
  • Composition for treatment, inhibition and attenuation of virus
    Patent number: 9694030
    Abstract: The embodiments herein relate to a therapeutically active composition for the treatment, inhibition or attenuation of a virus. The composition comprises an effective amount of a sulfur containing compound along with one or more pharmaceutically acceptable carriers or excipients. The sulfur containing compound impairs a disulfide bond of a plurality of virus. The plurality of virus includes Ebola virus, herpes virus, dengue virus, smallpox virus, measles virus, mumps rubella virus, HIV (human immunodeficiency virus), Lassa fever virus and yellow fever virus, and even cancer, solid tumors, especially the fibrosarcoma tumor. The sulfur containing compound is sodium thiosulfate (Na2S2O3) (“STS”). The composition is given orally, intravenously, inhalation, intravesical, vaginal, rectal, sublingual, ophthalmic, or topical.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: July 4, 2017
    Inventor: Frederick J. Sawaya
  • Method for isolating hepatitis A virus or spring viremia of carp virus
    Patent number: 8628916
    Abstract: A method for isolating Hepatitis A virus or Spring viremia of Carp virus. A virus probe is prepared by linking a magnetic bead-conjugated Protein G with an anti-HAV (Hepatitis A Virus) antibody or an anti-rhabdovirus antibody. The virus probe is contacted with a sample to be analyzed to form a virus probe-virus complex. The virus probe-virus complex is then isolated. It may specifically isolate Hepatitis A virus or Spring viremia of Carp virus from a sample mixed viruses.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: January 14, 2014
    Assignee: Industry Foundation of Chonnam National University
    Inventors: Du Woon Kim, Hee Min Lee, Se Young Cho, Sang Mu Ko, Kyung Seo Oh, Joseph Kwon, Jong Soon Choi
  • Virus co-processor instructions and methods for using such
    Patent number: 9219748
    Abstract: Circuits and methods for detecting, identifying and/or removing undesired content are provided. According to one embodiment, a method for virus processing is provided. A virus signature file that includes multiple virus signatures capable of detecting and identifying a variety of known viruses is downloaded by a general purpose processor. It is determined by the general purpose processor whether a virus co-processor is coupled to the general purpose processor. When the virus co-processor is determined to be coupled to the general purpose processor, then it is further determined by the general purpose processor which virus signatures are supported by the virus co-processor (“CP-supported virus signatures”). The CP-supported virus signatures are transferred to a memory associated with the virus co-processor. The virus co-processor is directed by the general purpose processor to perform a virus scan based on the supported virus signatures.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: December 22, 2015
    Assignee: Fortinet, Inc.
    Inventors: Lin Huang, Xu Zhou, Michael Xie
  • Method and system for retrieving an anti-virus signature from one or a plurality of virus-free certificate authorities
    Patent number: 6976271
    Abstract: A method and system as disclosed for use in a virus-free certificate proxy (107, 801), of retrieving from one or a plurality of virus-free certificate authorities (104, 804) a virus-free certificate (200) certifying that a file is virus-free. The method includes the steps of: receiving (1001) virus-free certificate request for a file; selecting a virus-free certificate authority (104, 804) having authority to generate a virus-free certificate (200) for the file; requesting (1003 . . . 1007) the virus-free certificate to the selected virus-free certificate authority (104, 804); receiving (1003 . . . 1007) from the selected virus-free certificate authority the generated virus-free certificate; sending back (1005) in response to the virus-free certificate request the received virus-free certificate.
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: December 13, 2005
    Assignee: International Business Machines Corporation
    Inventors: Jean-Francois Le Pennec, Olivier Hericourt
  • METHODS AND REAGENTS FOR DETECTION OF CHIKUNGUNYA VIRUS AND ZIKA VIRUS
    Publication number: 20190024195
    Abstract: Methods and oligonucleotide reagents for diagnosing chikungunya virus and Zika virus infections are described. In particular, the invention relates to quantitative assays that can detect all lineages of chikungunya virus and Zika virus and distinguish chikungunya virus and Zika virus from each other as well as dengue virus and other arbovirus pathogens.
    Type: Application
    Filed: January 14, 2017
    Publication date: January 24, 2019
    Inventors: Benjamin A. Pinsky, Jesse Waggoner
  • Software-hardware partitioning in a virus processing system
    Patent number: 7854008
    Abstract: Various embodiments of the present invention provide circuits and methods for improved virus processing. As one example, a method for virus processing is disclosed that includes providing a first memory that includes a first set of virus signatures, and a second memory that includes a second set of virus signatures. In addition, a virus co-processor and a general purpose processor are provided. The virus co-processor is communicably coupled to the first memory, and the general purpose processor is communicably coupled to the virus co-processor and to the second memory. A subset of the second set of virus signatures that is not included in the first set of virus signatures is determined. The subset of the second set of virus signatures is processed on the general processor, and the first set of the virus signatures is processed on the virus co-processor.
    Type: Grant
    Filed: August 10, 2007
    Date of Patent: December 14, 2010
    Assignee: Fortinet, Inc.
    Inventors: Lin Huang, Xu Zhou, Michael Xie
  • Methods and reagents for detection of chikungunya virus or chikungunya virus and dengue virus
    Patent number: 11591660
    Abstract: Methods and oligonucleotide reagents for diagnosing chikungunya virus and Zika virus infections are described. In particular, the invention relates to quantitative assays that can detect all lineages of chikungunya virus and Zika virus and distinguish chikungunya virus and Zika virus from each other as well as dengue virus and other arbovirus pathogens.
    Type: Grant
    Filed: January 14, 2017
    Date of Patent: February 28, 2023
    Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Benjamin A. Pinsky, Jesse Waggoner
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