Patents Represented by Attorney, Agent or Law Firm Barry L. Copeland
  • Chrondroitin sulfate/sodium hyaluronate composition
    Patent number: 6051560
    Abstract: Chondroitin sulfate/soduim hyaluronate compositions exhibiting pseudo-plastic behavior and non-Newtonian flow characteristics are disclosed.
    Type: Grant
    Filed: April 3, 1992
    Date of Patent: April 18, 2000
    Assignee: Nestle S.A.
    Inventors: Allison S. Chang, James E. Boyd, Richard M. Johnson, Harold O. Koch
  • substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
    Patent number: 6025392
    Abstract: Substituted tetrahydrofuran analogs of F-series prostaglandins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: July 2, 1998
    Date of Patent: February 15, 2000
    Assignee: Alcon Laboratories, Inc.
    Inventors: Robert D. Selliah, Mark R. Hellberg, Peter G. Klimko, Verney L. Sallee, Paul W. Zinke
  • Substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
    Patent number: 5994397
    Abstract: Substituted tetrahydrofuran analogs of prostagladins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: April 4, 1997
    Date of Patent: November 30, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Robert D. Selliah, Peter G. Klimko
  • Use of platelet derived growth factor to enhance wound healing
    Patent number: 5955436
    Abstract: Disclosed is the use of platelet derived growth factor for the enhancement of wound healing wherein the growth factor is either singularly or multiply dosed on a single day, rather than multiply dosed over a number of days. Also disclosed are pharmaceutical compositions comprising platelet derived growth factor.
    Type: Grant
    Filed: December 19, 1994
    Date of Patent: September 21, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventor: H. Melvin Kunkle, Jr.
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Patent number: 5889052
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues for the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic compositions comprising said compounds.
    Type: Grant
    Filed: August 21, 1997
    Date of Patent: March 30, 1999
    Assignee: Alcon Laboraties, Inc.
    Inventors: Peter G. Klimko, John E. Bishop, Verney L. Sallee, Paul W. Zinke
  • Keto-substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
    Patent number: 5866602
    Abstract: Keto-substituted tetrahydrofuran analogs of prostaglandins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: June 18, 1997
    Date of Patent: February 2, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventor: Robert D. Selliah
  • 9-oxa prostaglandin analogs as ocular hypotensives
    Patent number: 5814660
    Abstract: Substituted tetrahydrofuran analogs of prostaglandins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: June 18, 1997
    Date of Patent: September 29, 1998
    Assignee: Alcon Laboratories, Inc.
    Inventor: Robert D. Selliah
  • Combinations of prostaglandins and clonidine derivatives for the treatment of glaucoma
    Patent number: 5811443
    Abstract: Combinations of at least one clonidine derivative and at least one prostaglandin are used to treat glaucoma and ocular hypertension without some of the side effects typically associated with topical administration of prostaglandins.
    Type: Grant
    Filed: February 21, 1997
    Date of Patent: September 22, 1998
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Verney L. Sallee
  • Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
    Patent number: 5807892
    Abstract: Certain prostaglandin analogues are useful in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic, pharmaceutical compositions comprising such prostaglandin analogues.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 15, 1998
    Assignee: Alcon Laboratories, Inc.
    Inventors: Peter G. Klimko, Robert D. Selliah, Thomas R. Dean, Mark R. Hellberg, John E. Bishop
  • Use of certain 9-halo-13,14-dihydroprostaglandins to treat glaucoma and ocular hypertension
    Patent number: 5721273
    Abstract: 9-Halo-13,14-dihydroprostaglandins are useful in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic, pharmaceutical compositions comprising such prostaglandins.
    Type: Grant
    Filed: December 15, 1993
    Date of Patent: February 24, 1998
    Assignee: Alcon Laboratories, Inc.
    Inventors: Verney L. Sallee, Louis DeSantis, Jr., Paul W. Zinke, John E. Bishop
  • Use of 9-deoxy prostaglandin derivatives to treat glaucoma
    Patent number: 5698733
    Abstract: Disclosed are 9-deoxyprostaglandins which are useful in the treatment of glaucoma and ocular hypertension. Some of these 9-deoxyprostaglandins are novel. Also disclosed are ophthalmic, pharmaceutical compositions comprising such prostaglandins.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 16, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Mark R. Hellberg, Thomas R. Dean, Paul W. Zinke, Robert D. Selliah, John E. Bishop
  • Cloprostenol and fluprostenol analogues and their use to treat glaucoma and ocular hypertension
    Patent number: 5665773
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues for the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic compositions comprising said compounds.
    Type: Grant
    Filed: December 18, 1996
    Date of Patent: September 9, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Peter G. Klimko, John E. Bishop, Verney L. Sallee, Paul W. Zinke
  • Contact lens cleaning composition containing polyalkylene oxide modified siloxanes
    Patent number: 5654262
    Abstract: Compositions and methods are provided for cleaning and wetting of contact lenses, especially rigid, gas-permeable contact lenses. The compositions comprise low molecular weight polyalkylene oxide modified siloxanes, which are particularly effective in removing lipids from the surface of contact lenses.
    Type: Grant
    Filed: March 14, 1995
    Date of Patent: August 5, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Nayan N. Desai, Ronald P. Quintana, Masood A. Chowhan
  • Use of certain 9-haloprostaglandins to treat glaucoma and ocular hypertension
    Patent number: 5627209
    Abstract: 9-Haloprostaglandins are useful in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic, pharmaceutical compositions comprising such prostaglandins.
    Type: Grant
    Filed: October 25, 1995
    Date of Patent: May 6, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Verney L. Sallee
  • Combinations of prostaglandins and clonidine derivatives for the treatment of glaucoma
    Patent number: 5605922
    Abstract: Combinations of at least one clonidine derivative and at least one prostaglandin are used to treat glaucoma and ocular hypertension without some of the side effects typically associated with topical administration of prostaglandins.
    Type: Grant
    Filed: December 12, 1995
    Date of Patent: February 25, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Verney L. Sallee
  • Prostaglandin combinations in glaucoma therapy
    Patent number: 5565492
    Abstract: Disclosed is the use of combinations of F and E series prostaglandins and their respective derivatives and analogues, as well as pharmaceutically acceptable salts and esters thereof in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic, pharmaceutical compositions comprising said combinations.
    Type: Grant
    Filed: December 1, 1994
    Date of Patent: October 15, 1996
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis M. DeSantis, Verney L. Sallee
  • Compositions and methods for the treatment of the metabolically impaired and for improved compliance
    Patent number: 5521208
    Abstract: Disclosed are novel compositions comprising mixtures useful to treat the metabolically impaired and to improve patient compliance. Included are non-racemic mixtures of certain chiral spirofluorenehydantoins. Methods of use to treat glucose toxicity and complications arising from diabetes mellitus are also disclosed.
    Type: Grant
    Filed: July 29, 1993
    Date of Patent: May 28, 1996
    Assignee: Alcon Laboratories, Inc.
    Inventor: Billie M. York
  • Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
    Patent number: 5510383
    Abstract: Disclosed is the use of cloprostenol, fluprostenol, and their pharmaceutically acceptable salts and esters for the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic compositions comprising said compounds.
    Type: Grant
    Filed: August 3, 1993
    Date of Patent: April 23, 1996
    Assignee: Alcon Laboratories, Inc.
    Inventors: John E. Bishop, Louis DeSantis, Jr., Verney L. Sallee
  • Combinations of prostaglandins and clonidine derivatives for the treatment of glaucoma
    Patent number: 5480900
    Abstract: Combinations of at least one clonidine derivative and at least one prostaglandin are used to treat glaucoma and ocular hypertension without some of the side effects typically associated with topical administration of prostaglandins.
    Type: Grant
    Filed: April 10, 1995
    Date of Patent: January 2, 1996
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Verney L. Sallee
  • Use of combinations of viscoelastics during surgery
    Patent number: 5273056
    Abstract: A method for conducting ocular surgery using different viscoelastic agents is disclosed.
    Type: Grant
    Filed: June 12, 1992
    Date of Patent: December 28, 1993
    Assignee: Alcon Laboratories, Inc.
    Inventors: Richard N. McLaughlin, Ole J. Lorenzetti