Patents Represented by Attorney Edwin P. Ching

Find this attorney in the Justia Lawyer Directory

  • Purified mammalian CTLA-8 antigens and related reagents
    Patent number: 6562333
    Abstract: CTLA-8 antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigen. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: May 27, 1994
    Date of Patent: May 13, 2003
    Assignee: Schering Corporation
    Inventors: Pierre Golstein, Eric Rouvier, François Fossiez, Serge J. E. Lebecque
  • IL-17-like cytokine binding compounds and antibodies
    Patent number: 6562578
    Abstract: IL-17-like cytokines from mammals, reagents and diagnostic kits related thereto including purified proteins, specific antibodies, and nucleic acids are provided. Methods of using the reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: May 13, 2003
    Assignee: Schering Corporation
    Inventors: Daniel M. Gorman, J. Fernando Bazan, Robert A. Kastelein
  • DNA encoding mammalian CX3C chemokine genes
    Patent number: 6548654
    Abstract: Nucleic acids encoding a new family of chemokines, the CX3C family, from a mammal, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Grant
    Filed: May 16, 1996
    Date of Patent: April 15, 2003
    Assignee: Schering Corporation
    Inventors: Gerard T. Hardiman, Devora L. Rossi, Kevin B. Bacon, J. Fernando Bazan, Thomas J. Schall, Albert Zlotnik
  • Antibodies to mammalian T cell surface antigen
    Patent number: 6525180
    Abstract: Purified genes encoding a T cell surface antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this antigen are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: September 27, 2000
    Date of Patent: February 25, 2003
    Assignee: Schering Corporation
    Inventors: Daniel M. Gorman, Jeanine D. Mattson
  • Mammalian proteinases; oxidoreductases; related reagents
    Patent number: 6518405
    Abstract: Nucleic acids encoding various proteases, from a mammal, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: February 11, 2003
    Assignee: Schering Corporation
    Inventors: Lynette M. Dowling, Constance F. Huffine, Daniel M. Gorman
  • Mammalian chemokine reagents
    Patent number: 6512103
    Abstract: A novel CC chemokine which is from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said chemokine. A chemokine receptor is also provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: December 8, 1995
    Date of Patent: January 28, 2003
    Assignee: Schering Corporation
    Inventors: Daniel J. Dairaghi, Takahiko Hara, Atsushi Miyajima, Thomas J. Schall, Wei Wang, Akihiko Yoshimura
  • Nucleic acids encoding a cysteine rich protein
    Patent number: 6503730
    Abstract: Nucleic acids encoding a new family of small cysteine rich soluble proteins, from a mammal, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: January 7, 2003
    Assignee: Schering Corporation
    Inventors: Karin Franz-Bacon, Daniel M. Gorman, Terrill K. McClanahan
  • Il-b30 antibodies
    Patent number: 6495667
    Abstract: Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: December 17, 2002
    Assignee: Schering Corporation
    Inventor: J. Fernando Bazan
  • IL-B30 proteins
    Patent number: 6479634
    Abstract: Purified genes encoding cytokines from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using the reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: November 12, 2002
    Assignee: Schering Corporation
    Inventor: J. Fernando Bazan
  • Antibodies that specifically bind DNAX leukocyte associated immunoglobulin-like receptor
    Patent number: 6479638
    Abstract: Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using reagents relating to nucleic acids encoding monocyte cell proteins, and diagnostic kits, are also provided.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: November 12, 2002
    Assignee: Schering Corporation
    Inventors: Gosse Jan Adema, Linde Meyaard, Daniel M. Gorman, Terrill K. McClanahan, Sandra M. Zurawski, Gerard Zurawski, Lewis L. Lanier, Joseph H. Phillips, Jr.
  • Mammalian receptors for interleukin-10
    Patent number: 6423500
    Abstract: Receptor components for IL-10 are isolated and characterized. The amino acid sequence and nucleic acid encoding various species variants of the receptors are disclosed. Uses of the purified receptor gene and polypeptide are disclosed, including means for screening for agonists and antagonists of the receptor ligands, for producing diagnostic or therapeutic reagents, and for producing antibodies. Therapeutic or diagnostic reagents and kits are also provided.
    Type: Grant
    Filed: November 15, 1999
    Date of Patent: July 23, 2002
    Assignee: Schering Corporation
    Inventors: Kevin W. Moore, Ying Liu, Alice Suk-Yue Ho, Di-Hwei Hsu, Bazan Fernando J., Jimmy C. Tan, Chuan-Chu Chou
  • Nucleic acids encoding mammalian cell membrane protein MDL-1
    Patent number: 6416973
    Abstract: The purification and isolation of various genes which encode mammalian cell surface polypeptides. Nucleic acids, proteins, antibodies, and other reagents useful in modulating development of cells, e.g., lymphoid and myeloid, are provided, along with methods for their use.
    Type: Grant
    Filed: July 31, 1998
    Date of Patent: July 9, 2002
    Assignee: Schering Corporation
    Inventors: Alexander B. H. Bakker, Joseph H. Phillips, Lewis L. Lanier
  • Methods for modulating SLAM-expressing T cells
    Patent number: 6399065
    Abstract: Purified genes encoding a T cell surface antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this antigen. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: June 23, 1997
    Date of Patent: June 4, 2002
    Assignee: Schering Corporation
    Inventors: Gregorio Aversa, Chia-Chun J. Chang, Benjamin G. Cocks, Jan E. de Vries
  • Lymphotactin uses
    Patent number: 6395268
    Abstract: This invention relates to the use of lymphotactin or lymphotactin antagonists for administration to an animal. The administration of these therapeutic entities will attract certain cell types, or can be blocked to prevent such attraction. It also provides means to protect stem cells.
    Type: Grant
    Filed: December 8, 1999
    Date of Patent: May 28, 2002
    Assignee: Schering Corporation
    Inventors: Joseph A. Hedrick, Susan A. Hudak, Donna M. Rennick, Albert Zlotnik
  • Purified genes encoding mammalian cell surface antigens; proteins and antibodies
    Patent number: 6372899
    Abstract: Purified genes encoding a T cell surface antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigen. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: November 25, 1998
    Date of Patent: April 16, 2002
    Assignee: Schering Corporation
    Inventors: Gregorio Aversa, Chia-Chun J. Chang, Benjamin G. Cocks, Jan E. de Vries
  • Human JAK3 variants
    Patent number: 6372898
    Abstract: Muteins are provided, which are mutational variants of human Jak3 proteins. Particular positions of natural proteins are identified as critical in providing various different activities. Specific embodiments demonstrate properties of variations at these positions.
    Type: Grant
    Filed: November 13, 1998
    Date of Patent: April 16, 2002
    Assignee: Schering Corporation
    Inventors: Nicholas A. Cacalano, James A. Johnston
  • Isolated mammalian dendritic cell genes; related reagents
    Patent number: 6361939
    Abstract: Polynucleotides encoding various dendritic cell specific proteins from a primate are provided. Uses of purified sequences are also disclosed, including producing related reagents, e.g., specific antibodies, and purified proteins. Methods of using these reagents and related diagnostic kits are also described.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: March 26, 2002
    Assignee: Schering Corporation
    Inventors: Elizabeth Esther Mary Bates, Blandine Marie de Saint-Vis, Christophe Caux, Serge J. E. Lebecque, Jacques Banchereau
  • Human receptor proteins; related reagents and methods
    Patent number: 6326472
    Abstract: Nucleic acids encoding mammalian, e.g., human receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: October 14, 1998
    Date of Patent: December 4, 2001
    Assignee: Schering Corporation
    Inventors: Jacqueline C. Timans, Johannes Eduard Maria Antonius Debets, Theodore R. Sana, J. Fernando Bazan, Robert A. Kastelein
  • Use of interleukin-10 to produce a population of suppressor cells
    Patent number: 6277635
    Abstract: Interleukin-10 for producing a population of cells which are capable of inhibiting or suppressing reactions to alloantigens, for example in graft-versus-host disease or tissue rejection, is described. Interleukin-10 for reducing responses in mixed lymphocyte response (MLR) is also described. Exogenous or induced endogenous IL-10 may be used for the inhibition or suppression of the reactions to alloantigens.
    Type: Grant
    Filed: May 6, 1996
    Date of Patent: August 21, 2001
    Assignee: Schering Corporation
    Inventors: Maria-Grazia Roncarolo, Rene de Waal Malefyt, Rosa Bacchetta, Herve M. Groux, Jan E. de Vries
  • Intracellular regulatory molecules; related reagents
    Patent number: 6274312
    Abstract: Purified genes encoding intracellular regulatory molecules from a human, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding these molecules are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: December 10, 1997
    Date of Patent: August 14, 2001
    Assignee: Schering Corporation
    Inventors: Kurt C. Gish, Wolfgang Seghezzi, Frances Shanahan, Emma M. Lees, Terrill K. McClanahan