Patents Represented by Attorney Elias Lambiris
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Patent number: 8349592Abstract: The invention relates to a process of fermenting plant material in a fermentation medium into a fermentation product using a fermenting organism, wherein one or more aldehyde dehydrogenases are present in the fermentation medium.Type: GrantFiled: January 26, 2009Date of Patent: January 8, 2013Assignee: Novozymes North America, Inc.Inventors: Chee-Leong Soong, Jiyin Liu
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Patent number: 8338156Abstract: The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.Type: GrantFiled: June 18, 2010Date of Patent: December 25, 2012Assignee: Novozymes A/SInventors: Lene Lange, Wenping Wu, Dominique Aubert, Sara Landvik, Kirk Matthew Schnorr, Ib Groth Clausen
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Patent number: 8323946Abstract: The present invention relates to a method of constructing a variant of a parent Termamyl-like alpha-amylase, which variant has alpha-amylase activity and at least one altered property as compared to the parent alpha-amylase, comprises i) analyzing the structure of the parent Termamyl-like alpha-amylase to identify at least one amino acid residue or at least one structural part of the Termamyl-like alpha-amylase structure, which amino acid residue or structural part is believed to be of relevance for altering the property of the parent Termamyl-like alpha-amylase (as evaluated on the basis of structural or functional considerations), ii) constructing a Termamyl-like alpha-amylase variant, which as compared to the parent Termamyl-like alpha-amylase, has been modified in the amino acid residue or structural part identified in i) so as to alter the property, and, optionally, iii) testing the resulting Termamyl-like alpha-amylase variant with respect to the property in question.Type: GrantFiled: June 16, 2011Date of Patent: December 4, 2012Assignee: Novozymes A/SInventors: Allan Svendsen, Henrik Bisgard-Frantzen, Torben Vedel Borchert
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Patent number: 8309338Abstract: The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.Type: GrantFiled: April 25, 2011Date of Patent: November 13, 2012Assignee: Novozymes A/SInventors: Katja Salomon Johansen, Keith Gibson, Preben Nielsen, Helle Outtrup
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Patent number: 8273546Abstract: The invention relates to a process of fermenting plant material in a fermentation medium into a fermentation product using a fermenting organism, wherein one or more carbonic anhydrases are present in the fermentation medium.Type: GrantFiled: October 20, 2008Date of Patent: September 25, 2012Assignee: Novozymes North America, Inc.Inventors: Chee-Leong Soong, Jiyin Liu, Guillermo Coward-Kelly
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Patent number: 8263368Abstract: The invention relates to a novel Termamyl-like alpha-amylase, and Termamyl-like alpha-amylases comprising mutations in two, three, four, five or six regions/positions. The variants have increased thermostability at acidic pH and/or at low Ca2+ concentrations (relative to the parent).Type: GrantFiled: June 29, 2009Date of Patent: September 11, 2012Assignee: Novozymes A/SInventors: Allan Svendsen, Torben Vedel Borchert, Henrik Bisgard-Frantzen, Helle Outtrup, Bjarne Ronfeldt Nielsen, Vibeke Skovgaard Nielsen, Lisbeth Hedegaard
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Patent number: 8263381Abstract: The present invention relates to a hybrid enzyme comprising carbohydrate-binding module amino acid sequence and a fungal alpha-amylase amino acid sequence and to a variant of a fungal wild type enzyme comprising a carbohydrate-binding module and an alpha-amylase catalytic module. The invention also relates to the use of the hybrid enzyme or the variant in starch liquefaction.Type: GrantFiled: August 20, 2010Date of Patent: September 11, 2012Assignees: Novozyms A/S, Novozymes North America, Inc.Inventors: Hiroaki Udagawa, Rikako Taira, Shinobu Takagi, Carsten Hjort, Anders Vikso-Nielsen, Eric Allain, Shiro Fukuyama, Tomoko Matsui
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Patent number: 8263382Abstract: The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant has alpha-amylase activity and exhibits an alteration in at least one of the following properties relative to the parent alpha-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca2+ dependency and specific activity.Type: GrantFiled: May 4, 2011Date of Patent: September 11, 2012Assignee: Novozymes A/SInventors: Allan Svendsen, Torben Vedel Borchert, Henrik Bisgard-Frantzen
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Patent number: 8227221Abstract: The invention relates to a process of fermenting plant material in a fermentation medium into a fermentation product using a fermenting organism, wherein increased levels of one or more pyrophosphatase enzymes are present in the fermentation medium.Type: GrantFiled: November 19, 2008Date of Patent: July 24, 2012Assignee: Novozymes North America, Inc.Inventors: Chee-Leong Soong, Jiyin Liu, Zhengfang Kang
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Patent number: 8221743Abstract: The present invention relates to the use of isolated polypeptides as coccidiostats and/or histomonastats. An example of a polypeptide of the invention is the so-called L12 protein from Bacillus licheniformis ATCC 14580.Type: GrantFiled: December 13, 2007Date of Patent: July 17, 2012Assignee: Novozymes A/SInventors: Gilbert Weber, Jiri Broz
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Patent number: 8222006Abstract: The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.Type: GrantFiled: February 28, 2011Date of Patent: July 17, 2012Assignee: Novozymes A/SInventor: Allan Svendsen
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Patent number: 8216817Abstract: The invention relates to an improved process of producing a fermentation product, such as ethanol, from starch-containing material using an increased dosage of alpha-amylase during liquefaction, which results in increased conversion of dextrins compared to conventional processes, and/or a reduced dosage of carbohydrate-generating enzyme during simultaneous saccharification and fermentation compared to a conventional process carried out at the same conditions. A process of the invention results in an increased yield. The invention also relates to an improved process of producing a fermentation product resulting in substantially the same yield as a conventional process, wherein reduced dosage of carbohydrate-source generating enzyme is used during simultaneous saccharification and fermentation.Type: GrantFiled: September 19, 2006Date of Patent: July 10, 2012Assignee: Novozymes North America, Inc.Inventors: George E. Gill, Billie Jean Savage, Swapnil Bhargava
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Patent number: 8206962Abstract: The present invention relates to phytases having at least 76% identity to a phytase derived from Hafnia alvei and comprises at least one modification in the amino acid sequence thereof. These phytase variants have modified, preferably improved, properties, such as, reduced protease sensibility, preferably they exhibit improved properties in respect of thermal performance, such as heat-stability (temperature stability, thermostability), steam stability, pelleting stability and/or temperature profile; and/or protease stability, in particular pepsin stability, pH profile, specific activity, substrate specificity, performance in animal feed (such as an improved release and/or degradation of phytate), susceptibility to glycation, and/or glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.Type: GrantFiled: September 28, 2009Date of Patent: June 26, 2012Assignee: Novozymes A/SInventors: Soeren Flensted Lassen, Leonardo De Maria, Esben Peter Friis, Tomoko Matsui, Allan Noergaard, Lars Kobberoee Skov, Jesper Vind
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Patent number: 8198068Abstract: A method of forming localized variation of color density in the surface of a dyed cellulosic fabric with reducing back staining, with a composition comprising a cellulose having the amino acid sequence of SEQ ID NO: 2 or an amino acid sequence having at least 75% sequence identity with SEQ ID NO: 2 is provided. A method for biopolishing a cellulose-containing fabric by using the new endoglucanase is also provided.Type: GrantFiled: February 19, 2009Date of Patent: June 12, 2012Assignee: Novozymes A/SInventors: Guifang Wu, Sarah Teter, Paul Harris, Weijian Lai
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Patent number: 8192925Abstract: The present invention relates to isolated polypeptides having antimicrobial activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.Type: GrantFiled: May 13, 2008Date of Patent: June 5, 2012Assignee: Novozymes Adenium Biotech A/SInventors: Per Holse Mygind, Mogens Trier Hansen, Marianne Vind Sorensen, Dorthe Sandvang
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Patent number: 8148127Abstract: The present invention relates to polypeptides having glucoamylase activity and isolated polynucleotides encoding said polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides. The invention also relates to the composition comprising a glucoamylase of the invention as well as the use such compositions for starch conversion processes, brewing, including processes for producing fermentation products or syrups.Type: GrantFiled: December 10, 2009Date of Patent: April 3, 2012Assignees: Novozymes A/S, Novozymes North America, Inc.Inventors: Hiroaki Udagawa, Sara Landvik, Michiko Ihara, Jiyin Liu, Chee Leong Soong, Eric Allain, Shiro Fukuyama
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Patent number: 8143047Abstract: The invention relates to functional polypeptides secreted from Botryospaeria rhodina CBS 274.96.Type: GrantFiled: December 4, 2009Date of Patent: March 27, 2012Assignee: Novozymes AlsInventors: Kirk Matthew Schnorr, Lene Lange, Pernille Uldall Bolvig
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Patent number: 8124395Abstract: The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant exhibits altered properties, in particular reduced capability of cleaving a substrate close to the branching point, and improved substrate specificity and/or improved specific activity relative to the parent alpha-amylase.Type: GrantFiled: November 23, 2010Date of Patent: February 28, 2012Assignee: Novozymes A/SInventors: Carsten Andersen, Christel Thea Jorgensen, Henrik Bisgard-Frantzen, Allan Svendsen, Soren Kjaerulff
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Patent number: 8124396Abstract: The formation of acrylamide during heat treatment in the production of a food product is reduced by treating the raw material with an enzyme before the heat treatment. The enzyme is capable of reacting on asparagine or glutamine (optionally substituted) as a substrate or is a laccase or a peroxidase.Type: GrantFiled: December 7, 2007Date of Patent: February 28, 2012Assignee: Novozymes A/SInventors: Gitte Budolfsen, Morten Tovborg Jensen, Hans Peter Heldt-Hansen, Mary Ann Stringer, Lene Lange
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Patent number: 8119386Abstract: The present invention relates to isolated proteases of the RP-II type and variants of RP-II proteases exhibiting improved properties in comparison to the parent RP-II protease, DNA constructs and vectors coding for the expression of said proteases and variants, host cells capable of expressing the proteases and variants from the DNA constructs, as well as a method of producing them by cultivating said host cells. The proteases may advantageously be used as constituents in detergent compositions and additives, optionally in combination with other enzymes such as proteases, lipases, cellulases, amylases, peroxidases or oxidases.Type: GrantFiled: January 26, 2011Date of Patent: February 21, 2012Assignee: Novozymes AlsInventors: Mads Norregaard-Madsen, Peter Rahbek Ostergaard, Claus Bo Voge Christensen, Soren Flensted Lassen