Patents Represented by Attorney Elias Lambiris
  • Patent number: 7635470
    Abstract: A novel fungal enzyme having lysozyme activity has been isolated. The invention further relates to a fungal polypeptide having lysozyme activity and belonging to the GH25 family, wherein the enzyme is selected from the group consisting of (a) a polypeptide comprising an amino acid sequence, which has at least 80% identity with amino acids 1 to 233 of SEQ ID NO:2; (b) a polypeptide comprising an amino acid sequence, which has at least 80% identity with the polypeptide encoded by the lysozyme encoding part of the nucleotide sequence inserted into a plasmid present in strain DSM 16084; (c) a polypeptide which is encoded by a nucleotide sequence which hybridizes under high stringency conditions with a polynucleotide probe consisting of the complementary strand of nucleotides 84 to 782 of SEQ ID NO:1; or (d) a fragment of (a), (b) or (c) that has lysozyme activity.
    Type: Grant
    Filed: February 16, 2006
    Date of Patent: December 22, 2009
    Assignee: Novozymes A/S
    Inventors: Wenping Wu, Kirk Matthew Schnorr
  • Patent number: 7618795
    Abstract: The present invention relates to a process for enzymatic hydrolysis of granular starch into a soluble starch hydrolysate at a temperature below the initial gelatinization temperature of said granular starch.
    Type: Grant
    Filed: June 25, 2004
    Date of Patent: November 17, 2009
    Assignee: Novozymes A/S
    Inventors: Anders Vikso-Nielsen, Carsten Andersen, Sven Pedersen, Carsten Hjort
  • Patent number: 7611882
    Abstract: Detergent composition comprising a surfactant and a pectate lyase (EC 4.2.2.2) enzyme en-coded by a DNA sequence endogeneous to a strain of Bacillus subtilis or a stabilized variant thereof provides superior cleaning and stain removal.
    Type: Grant
    Filed: May 14, 2002
    Date of Patent: November 3, 2009
    Assignee: Novozymes A/S
    Inventors: Mads Eskelund Bjørnvad, Martin Schülein, Torben Henriksen, legal representative, Vibeke Skovgaard Nielsen, Johan Smets, Carsten Andersen, Thomas Thisted
  • Patent number: 7608444
    Abstract: The present invention relates to acid-stable proteases of the subtilisin family, their use in animal feed, feed-additives and feed compositions containing such proteases, and methods for the treatment of vegetable proteins using such proteases.
    Type: Grant
    Filed: March 8, 2005
    Date of Patent: October 27, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Peter Rahbek Oestergaard, Carsten Sjoeholm, Anna-Marie Kluenter
  • Patent number: 7605115
    Abstract: New subtilisin homologues (both nucleic acids and proteins) are provided. Compositions which include these new proteins, recombinant cells, shuffling methods involving the new homologues, antibodies to the new homologues, and methods of using the homologues are also provided.
    Type: Grant
    Filed: April 17, 2007
    Date of Patent: October 20, 2009
    Assignees: Novozymas Als, Maxygen Inc.
    Inventors: Jon E. Ness, Mark Welch, Lorraine J. Giver, Joel R. Cherry, Torben V. Borchert, Jeremy Minshull
  • Patent number: 7601529
    Abstract: The present invention relates to pectate lyase variants exhibiting alterations relative to a parent enzyme exhibiting pectate lyase activity as its major enzymatic activity; to a method of producing such enzymes; and to methods for using such enzymes in the textile, detergent and cellulose fiber processing industries. Compared to the parent enzyme, the pectate lyase variants of the present invention exhibit improved stability in detergents.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: October 13, 2009
    Assignee: Novozymes A/S
    Inventors: Sanne Schroder Glad, Carsten Andersen, Torben Vedel Borchert, Katja Salomon Johansen, Henrik Frisner, Thomas Thisted, Mads Eskelund Bjornvad
  • Patent number: 7579177
    Abstract: The present invention relates to processes for production of an alcohol product from granular starch comprising a pre-treatment at an elevated temperature below the initial gelatinization temperature of said granular starch followed by simultaneous saccharification and fermentation.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: August 25, 2009
    Assignee: Novozymes A/S
    Inventors: Hans Sejr Olsen, Barrie Edmund Norman, Mogens Wumpelmann, Jeppe Wegener Tams
  • Patent number: 7537921
    Abstract: Variants of Glycoside Hydrolase family 53 galactanases, e.g. variants of the galactanases from strains of Yersinia, Aspergillus, Humicola, Meripilus, Myceliophthora, Thermomyces, Bacillus, Bifidobacterium, Cellvibrio, Clostridium, Pseudomonas, Thermotoga, or Xanthomonas.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: May 26, 2009
    Assignee: Novozymes A/S
    Inventors: Leonardo De Maria, Allan Svendsen, Torben Vedel Borchert, Lars Lehmann Hylling Christensen, Sine Larsen, Carsten Ryttersgaard
  • Patent number: 7456001
    Abstract: The invention provides sequence information of a microbial protein having lipoxy-genase activity and a method of producing the protein by recombinant DNA technology. More specifically, the inventors have isolated a gene encoding a lipoxygenase from Gaeu-mannomyces graminis, cloned it into an E. coli strain and sequenced it. A comparison shows less than 25% identity to known lipoxygenase sequences, the closest being human 15S li-poxygenase. The inventors have expressed the lipoxygenase recombinantly and found that the recombinant lipoxygenase is glycosylated.
    Type: Grant
    Filed: September 5, 2001
    Date of Patent: November 25, 2008
    Assignee: Novozymes A/S
    Inventors: Soren Christensen, Akiko Sugio, Shinobu Takagi, Lars Ostergaard, Ernst Oliw
  • Patent number: 7407793
    Abstract: The present invention relates to a consortium of Nitrosomonas eutropha and Nitrobacter winogradskyi, which is more effective at removing ammonia and nitrite than the commonly used consortium of Nitrosomonas europea and Nitrobacter winogradskyi, particularly in aquaculture such as shrimp ponds. Supplementation of the consortium in aquaculture such as shrimp ponds may lead to an increase in total yield, an increase in size, a decrease in Food Conversion Ratio (less food required per kg of shrimp obtained), and an increase in total per pond sales.
    Type: Grant
    Filed: October 11, 2005
    Date of Patent: August 5, 2008
    Assignee: Novozymes Biologicals, Inc.
    Inventor: David J. Drahos
  • Patent number: 7348168
    Abstract: The present invention relates to polypeptides having cellobiohydrolase II activity and polynucleotides having a nucleotide sequence, which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: March 25, 2008
    Assignee: Novozymes A/S
    Inventors: Wenping Wu, Lene Lange, Dominique Aubert Skovlund, Ye Liu
  • Patent number: 7326554
    Abstract: The present invention relates to phytase variants, their preparation and uses, which phytase variants, when aligned according to FIG. 1, are amended as compared to a model phytase in at least one of a number of positions. Preferred model phytases are basidiomycete and ascomycete phytases, such as Peniophora phytase and Aspergillus phytases. Preferred phytase variants exhibits amended activity characteristics, such as improved specific activity and/or improved thermostability.
    Type: Grant
    Filed: December 12, 2003
    Date of Patent: February 5, 2008
    Assignee: Novozymes Als
    Inventors: Allan Svendsen, Soren Flensted Lassen, Dirk Kostrewa, Luis Pasamontes, Martin Lehman, Andrea Tomschy, Adolphus Van Loon, Kurt Vogel, Markus Wyss
  • Patent number: 7192757
    Abstract: The present invention relates to subtilase variants having a reduced tendency towards inhibition by substances present in eggs, such as trypsin inhibitor type IV-0. In particular, the variants comprise at least one additional amino acid residue between positions 42–43, 51–56, 155–161, 187–190, 216–217, 217–218 or 218–219 (in BASBPN numbering). These subtilase variants are useful exhibiting excellent or improved wash performance on egg stains when used in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dishwash composition, including automatic dishwash compositions. Also, isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention. Further, cleaning and detergent compositions comprising the variants are disclosed.
    Type: Grant
    Filed: July 2, 2004
    Date of Patent: March 20, 2007
    Assignee: Novozymes A/S
    Inventors: Mads Nørregard-Madsen, Line Bloch Larsen, Peter Kamp Hansen
  • Patent number: 7183086
    Abstract: The present invention relates to a process for enzymatic hydrolysis of cyclic oligomers of poly(ethylene terephthalate), which process comprises subjecting the cyclic oligomer to the action of one or more lipolytic and/or biopolyester hydrolytic enzyme(s).
    Type: Grant
    Filed: February 25, 2003
    Date of Patent: February 27, 2007
    Assignee: Novozymes A/S
    Inventors: Martin Riegels, Rainhard Koch, Lars Saaby Pedersen, Henrik Lund
  • Patent number: 7090876
    Abstract: The present invention relates to a method for producing a fermented dairy product including the use of an oxidase for the conversion of lactose to lactobionic acid. Moreover, it refers to a method for affecting firmness and/or sourness of a fermented dairy product. Hereby is produced a fermented dairy product having improved functional and/or organoleptic properties.
    Type: Grant
    Filed: October 29, 2002
    Date of Patent: August 15, 2006
    Assignee: Novozymes A/S
    Inventor: Gitte Budolfsen Lynglev
  • Patent number: 7078213
    Abstract: The present invention relates to amylases having improved washing performance in an alkaline detergent solution at low temperature. More specifically, the present invention provides novel ?-amylases from Bacillus sp. with improved performance in alkaline solutions, especially in alkaline detergent solutions at pH around 9–11.
    Type: Grant
    Filed: August 24, 1999
    Date of Patent: July 18, 2006
    Assignee: Novozymes A/S
    Inventors: Helle Outtrup, Bjarne Rønfeldt Nielsen, Lisbeth Hedegaard, Jens Toenne Andersen
  • Patent number: 7041488
    Abstract: An enzyme exhibiting endo-beta-1,4-glucanase activity (EC 3.2.1.4), which is selected from one of a) a polypeptide encoded by the DNA sequence of positions 1 to 2322 of SEQ ID NO:1,b) a polypeptide produced by culturing a cell comprising the sequence of SEQ ID NO:1 under conditions wherein the DNA sequence is expressed; c) an endo-beta-1,4-glucanase enzyme having a sequence of at least 97% identity to the amino acid sequence of position 1 to position 773 of SEQ ID NO:2, and fragments thereof exhibitng endo-beta-1,4-glucanase activity, and d) a polypeptide having endo-beta-1,4-glucanase activity that is encoded by a polynucleo-tide that hybridizes with the nucleotide sequence shown in positions 1-2322 of SEQ ID NO:1, is useful for detergent and textile applications.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: May 9, 2006
    Assignee: Novozymes A/S
    Inventors: Helle Outtrup, Torben Henriksen, Mads Eskelund Bjørnvad, Martin Schülein
  • Patent number: 6940002
    Abstract: A transgenic plant cell expressing a maltogenic amylase (such as Novamyl®) or a beta-amylase; a transgenic plant regenerated from said cell; seeds generated from such plant where said seeds comprise a maltogenic amylase or a beta-amylase and the use of said seeds, optionally in ground form, for catalyzing an industrial process, such as e.g. in baking. The maltogenic amylase providing an anti staling effect in bread produced from the seeds in question.
    Type: Grant
    Filed: November 12, 1999
    Date of Patent: September 6, 2005
    Assignee: Novozymes A/S
    Inventors: Jack Bech Nielsen, Søren Kjærulff
  • Patent number: 6933141
    Abstract: The invention relates to an enzyme-containing granule comprising a core unit and a shell unit, wherein the core unit comprises the enzyme and is enclosed in a shell unit which is substantially enzyme-free, the ratio between the diameter of the granule and the diameter of the core unit being at least 1.1. Also processes for producing such granules and use of the granules are disclosed.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: August 23, 2005
    Assignee: Novozymes A/S
    Inventor: Poul Bach
  • Patent number: 6924133
    Abstract: The invention relates to a particle comprising an enzyme and a biomass, to a process for preparing a particle comprising spray drying an enzyme and biomass containing fermentation broth starting material, to obtain a solid particle comprising an enzyme and a biomass and to a process for preparing an enzyme containing particle comprising spray drying an aqueous enzyme containing liquid starting material to obtain a spray dried first enzyme containing particle and subsequently subjecting the first dry particle to a process selected from granulation and coating and combinations thereof to obtain a second dry enzyme containing particle.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: August 2, 2005
    Assignee: Novozymes A/S
    Inventors: Jørgen Topp Jørgensen, Carsten Jacobsen, Kim Uhre Hansen, Anders Jørgensen, Dan Oftelund, Poul Bach, Gustav Borup Søndergaard