Abstract: Compositions including a quinolone component in an amount effective as an antibiotic when the composition is placed in a mammalian eye, and a carrier component in an amount effective to act as a carrier for the quinolone component are provided. The present compositions are substantially free of other components effective as preservatives. Preferably the quinolone component has fungistatic activity. In one very useful embodiment, the compositions include a NSAID component in an amount effective to reduce inflammation or pain when the composition is placed in a mammalian eye. Methods of using the present compositions, for example, to resolve microbial infections and/or to reduce inflammation and/or pain in a mammalian eye are included within the scope of the present invention.

Abstract: Methods for producing contact lenses for are provided including transferring an iris-simulating pattern to a contact lens substrate. The iris-simulating pattern is obtained from a digitized image of an iris of an eye. Contact lenses including such iris-simulating patterns are also provided.

Abstract: A tinted contact lens for insertion into an eye comprises a contact lens substrate and an iris-simulating pattern on the lens substrate. The iris simulating pattern comprises at least four distinctly colored colorants. A method for making a tinted contact lens for insertion into an eye comprises providing a plate having a surface, and lasing the plate to form at least one depression in the surface of the plate. The depression is of a shape constituting an iris portion pattern. A fluent colorant is introduced into the depression. The colorant is then transferred from the depression to a lens substrate in a manner so that the colorant colors the lens substrate in a colorant pattern of substantially the same shape as the iris portion pattern of the depression.

Abstract: A golf training device which clamps onto the shaft of a standard golf club. The device has a holding block which holds a laser pointing in a downward direction. A hinged mirror at the light emitting end of the laser causes the laser light to be reflected at roughly a ninety degree angle and thereby run parallel to the ground. An alignment strip and separate target helps the user calibrate the training device so that the laser beam is perpendicular to the flat head striking area of the golf club. The alignment strip can then be removed allowing the user to move the target to any reasonable distance. In this way a golfer can learn the proper alignment of club head to hole thereby improving his or her ability to accurately putt a golf ball towards and into the hole. The hinged mirror on the training device of the present invention can also be swung down so that the laser light is pointing straight down.

Abstract: Compositions useful for repairing osseous defects and healing of wounds and burns include particulate bioactive and biocompatible glass including 40 to 58% by weight silica, 10 to 32% by weight calcia, 10 to 32% by weight soda, 2 to 10% by weight phosphorus pentoxide and 0 to 8% by weight silver oxide. The particles have a size distribution of: less than 500 microns. Methods for repairing osseous defects, healing wounds and burns utilizing such compositions are also provided.

Abstract: Multi-purpose solutions for contact lens care provide substantial lens wearer/user comfort and/or acceptability. Such solutions include an aqueous liquid medium; an antimicrobial component, preferably a biguanide polymer present in an amount of less than about 5 ppm; a surfactant component, preferably a poly(oxyethylene)-poly(oxypropylene) block copolymer surfactant, in an effective amount; a phosphate buffer component in an effective amount; a viscosity inducing component, preferably selected from cellulosic derivatives, in an effective amount; and a tonicity component in an effective amount. Such solutions have substantial performance, comfort and-acceptability benefits, which, ultimately, lead to ocular health advantages and avoidance of problems caused by contact lens wear.

Abstract: An intraocular lens configured to be implanted in the cornea from the posterior aspect. The lens has an optic and a pair fixation members extending outward therefrom. One of the fixation members includes a single enlarged foot, while the other fixation member has two bifurcated feet. The fixation members are sized and shaped to fix within tunnels formed in the cornea. A method of the invention includes forming tunnels in the stroma layer of the cornea, and positioning the fixation members in the tunnels. The tunnels may be formed from outside or inside the cornea. The method may include inserting the folded intraocular lens into the anterior chamber, permitting the lens to unfold, inserting the fixation member with the enlarged foot in one of the tunnels, and bending the two bifurcated feet of the other fixation member together so as to fit within the other tunnel.

Abstract: Iris fixated intraocular lenses include an optic and at least one fixation member or haptic. The fixation member is joined to the optic and has a distal segment including a through-iris portion adapted to extend through an iris hole, and an anchor portion. The anchor portion has or is adapted to have an anchor structure positioned to be disposed proximate to a side of the iris so as to be a effective in fixating the intraocular lens to the iris. The anchor structure may be formed prior to inserting the intraocular lens in the eye or may be formed after the intraocular lens is inserted in the eye. Methods for inserting such intraocular lenses in the eye are also provided.

Abstract: An intraocular lens having an optic and a plurality of fixation members coupled to the optic. The fixation members are adapted to be evenly circumferentially distributed about the anterior chamber to reduce the phenomenon of malshaping the iris, for example, pupil ovalling.

Abstract: An intraocular lens implantable in an eye includes an optic for placement in the capsular bag of the eye and for directing light toward the retina of the eye. The optic has a central optical axis, an anterior face, an opposing posterior face and a peripheral edge between the faces. The peripheral edge has one or more curved or angled surfaces that reduce glare within the IOL. For instance, a rounded transition surface on the anterior side of the peripheral edge diffuses the intensity of reflected light, or a particular arrangement of straight edge surfaces refracts the light so as not to reflect, or does not reflect at all. The intersection of the peripheral edge and at least one of the anterior face and the posterior face, preferably both of such faces, forms a peripheral corner located at a discontinuity between the peripheral edge and the intersecting face or faces.

Abstract: A contact lens having a rotational stabilization mechanism thereon, such as prism ballast, and a thickness profile that reduces the torque imparted on the lens by the action of the eyelids, especially for stabilizing toric lenses. The prism ballast is provided on one or more portions of the anterior face of the lens such that the lens body has a uniform thickness of within 10% along horizontal cross-sections. The anterior face of the lens may be segregated into a peripheral zone, an inner zone circumscribed by the peripheral zone, and a central optic zone. The prism ballast portion is provided within the inner zone, which may be further subdivided into a superior portion, an intermediate portion proximate the optic zone, and an inferior portion. The ballast portion increases in thickness along a superior-inferior line parallel to a vertical meridian, and has a substantially uniform thickness perpendicular thereto. The peripheral zone may be tapered, and have a rounded edge.

Abstract: A therapeutic system comprising an orthotic device adapted to extend the range of angular movement between adjacent first and second skeletal body parts which have been drawn to and involuntarily held in a limited angular range of motion position relative to one another by contraction of muscle fibers and connective tissue due to immobility of one or both of said skeletal body parts and an electrode component positioned to be effective to conduct an electrical current to at least one of said body parts.

Abstract: A supplemental intraocular lenses may be attached to conventional primary intraocular lenses using annular wrap-around clamps or adhesive. New primary intraocular lens configurations have pockets for accommodating relatively small, supplemental intraocular lenses therein.

Abstract: Compositions which have substantial weatherability and impact resistance include a substantially uniform blend of an acrylonitrile/styrene/acrylic polymeric material and a wood component in an amount effective as a filler in the composition. Methods for making such compositions include forming a substantially uniform physical mixture of such polymeric material and wood component.

Abstract: Compositions which have substantial weatherability and impact resistance include a substantially uniform blend of an acrylonitrile/styrene/acrylic polymeric material and a component selected from (A) polymeric materials including units derived from ethylene, carbon monoxide and copolymerizable ethylenically unsaturated organic compounds, (B) graft polymer components including ethylene-propylene-non-conjugated diene terpolymers grafted with styrene and acrylonitrile monomers, and mixtures thereof. Methods for making such compositions include forming a substantially uniform physical mixture of such polymeric material and component.

Abstract: An IOL insertion apparatus including a cartridge with an IOL-receiving chamber, a handpiece into which the cartridge is loaded, and a plunger rod that extends through a lumen in the cartridge to reliably engage the IOL therein. The chamber has a recess in one wall that creates a space adjacent the proximal edge of the IOL positioned therein. A lip or projection on the plunger rod is aligned with the space to extend underneath the proximal edge of the IOL. The plunger rod may define a forked end with a groove into which the proximal edge of the IOL is captured. The cartridge may be of the type that folds the IOL therein. The recess may continue the entire length of the cartridge to guide the plunger rod therethrough. The cartridge lumen may converge so that the IOL is further compressed therealong. An inwardly-directed wall portion in the cartridge may help guide the lip of the plunger rod into the recess.

Abstract: Ophthalmic lenses, for example, intraocular lenses, contact lenses, corneal implant lenses and the like, have multifocal characteristics which provide beneficial reductions in at least the perception of one or more night time visual symptoms such as “halos”, and “glare or flare”.

Abstract: Nipples, for example, useful in joining a spoke to the rim of a bicycle wheel, are provided. Such nipples include an enlarged head, and an elongated shank joined to and extending from the enlarged head and having an outer peripheral surface; and a passageway including an inlet defined by the elongated shank. The passageway is at least partially defined by an interior surface of the elongated shank and by a threaded surface. The outer peripheral surface of the elongated shank includes at least one spline, preferably a plurality of splines, each of which extends generally longitudinally. The inclusion of such spline or splines has been found to allow the nipple to be turned so as to effectively tighten the spoke to the rim with a reduced risk of damaging the nipple. Apparatus useful for turning such nipples and spoked wheels including such nipples are also within the scope of the present invention.