Abstract: A delivery system for endovascularly delivering a prosthesis along a guidewire to a curved implantation site includes a delivery device having control handle and an inner lumen slidably disposed in the handle between a retracted position and an extended position. The inner lumen has a distal end and a tip at the distal end of the inner lumen. An intermediate lumen is slidably disposed about the inner lumen and has a distal end. A relatively flexible prosthesis sheath is connected to the distal end of the intermediate lumen and a relatively stiff outer lumen is axially fixedly connected to the handle about the intermediate lumen. The outer lumen has a length only long enough to be inserted in a patient's aorta no further than the patient's celiac axis.

Abstract: A compound for use in treating polycystic kidney disease is represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating polycystic kidney disease in a subject in need thereof comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. Methods of treating in polycystic kidney disease in a subject in need thereof respectively comprise administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.

Abstract: A method and system capable of creating UML protocol state machine for classes and interfaces of a software, by instrumenting the software to obtain a call graph comprising classes and interfaces and respective values associated with class variables and interface variables; identifying particular classes and interfaces in the call graph; identifying call patterns from the call graph to generate a protocol state machine.

Abstract: An equalizer provided in a digital transmitter compensates for attenuation in a signal channel to a digital receiver. The equalizer generates signal levels as a logical function of bit history to emphasize transition signal levels relative to repeated signal levels. The preferred equalizer includes an FIR transition filter using a look-up table. Parallel circuits including FIR filters and digital-to-analog converters provide a high speed equalizer with lower speed circuitry. The equalizer is particularly suited to in-cabinet and local area network transmissions where feedback circuitry facilitates adaptive training of the equalizer.

Abstract: A compound is represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating a subject in need thereof comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. The subject has type 2 diabetes; renal hypertrophy or hyperplasia associated with diabetic nephropathy; Tay-Sachs; Gaucher's; or Fabry's disease. Methods of decreasing plasma TNF-?, lowering blood glucose levels, decreasing glycated hemoglobin levels, inhibiting glucosylceramide synthase, and lowering glycosphingolipid concentrations in a subject in need thereof respectively comprise administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.

Abstract: Updating a three-dimensional model includes generating a three-dimensional model comprised of components, modifying one of the components, determining other components having a possible changing effect on the three-dimensional model as a result of modifying the one component, and constructing a modified version of the three-dimensional model by regenerating the modified component and the other components having the possible changing effect while not regenerating remaining ones of the components not having the possible changing effect. The modified version achieves the same result as revising the three-dimensional model by regenerating each one of components.

Abstract: The present invention relates to an anchor configured for minimally-invasive implantation and sized to remain securely positioned within at least a portion of the gastrointestinal tract of an animal. The anchor includes a radial spring formed from an elongated resilient member shaped into an annular wave pattern about a central axis. The anchor defines a central lumen and provides an outward radial force, while allowing for substantial flexure about its perimeter. The anchor is generally removable, but can include fasteners, such as barbs, to further secure it to the surrounding anatomy. In some embodiments, the anchor includes a connector coupling a fixed portion to a removable portion. Further, the anchor can be used to secure a medical device within the body, such as a flexible sleeve within the intestine.

Abstract: The present invention relates generally to a method for modulating cell survival. Modulation of cell survival includes inducing, enhancing or otherwise promoting cell survival such as the survival of neural cells as well as facilitating cell death such as the death of targeted cancer cells. The modulation of cell survival is mediated by a region identified on the p75 neurotrophin receptor (p75NTR) required for death signalling. The present invention further provides genetic molecules which encode the death signalling region of p75NTR which are useful in antagonising death signal function as well as promoting cell death when expressed in targeted cells. The present invention also contemplates recombinant peptides, polypeptides and proteins as well as chemical equivalents, derivatives and homologues thereof which comprise the death signalling portion of p75NTR. Particularly useful molecules of the present invention comprise peptides corresponding to soluble forms of the death signalling portion of p75NTR.

Abstract: An Agile-Beam Laser Array Transmitter (ABLAT) uses an array of emitters and an array of lenses to project electromagnetic beams over a wide angular coverage area in the far field. Differences in the separation pitches of the two arrays allows the ABLAT to project beams to contiguous and/or overlapping positions, depending on the ratio of the separation pitches and the lens focal length. Compared to other beam steering technology, the ABLAT is a smaller, lighter, and more efficient means of projecting beams over wider angular coverage areas. Various embodiments can be used in any beam steering application, including, but not limited to: free-space optical communications; light detection and ranging (lidar); optical scanning (e.g.

Abstract: A method of and apparatus for allowing a user to access an electronic device by entering a password from a first device having alphabetic letter keys and numerical digit keys and a second device having primarily numerical digit keys comprising creating an alphabetic letter conversion relationship between the alphabetic letter keys of the first device with the numerical digit keys of the second device, creating a numerical digit conversion relationship between the numerical digit keys of the first device with the numerical digit keys of the second device, receiving a first password entered from the first device having alphabetic letter keys and numerical digit keys, converting the first password to a second password that can be entered from the second device having primarily numerical digit keys by using the alphabetic letter conversion relationship and the numerical digit conversion relationship, and allowing a user to access the electronic device if the user enters the first password or the second password.

Abstract: A computer-readable instruction is described for traversing deterministic finite automata (DFA) graphs to perform a pattern search in the in-coming packet data in real-time. The instruction includes one or more pre-defined fields. One of the fields includes a DFA graph identifier for identifying one of several previously-stored DFA graphs. Another one of the fields includes an input reference for identifying input data to be processed using the identified DFA graphs. Yet another one of the fields includes an output reference for storing results generated responsive to the processed input data. The instructions are forwarded to a DFA engine adapted to process the input data using the identified DFA graph and to provide results as instructed by the output reference.

Abstract: A product lifecycle management system cannot interact with 3D models and data representing a product or process that lacks information for creating a three-dimensional model in a seamless and uniform manner. Such incompatible data includes legacy and conceptual data. Accordingly, a method and corresponding apparatus according to an embodiment of the present invention are provided to create from such data, an intermediary representation that is compatible with the three-dimensional model domain but differs from a three-dimensional model that has real-world geometry of the product or process. The intermediary structure is formed in a manner that enables the product lifecycle management system to interact with the intermediary representation and three-dimensional models in a seamless and uniform manner, and is capable of being updated with real-world geometry of the product or process.

Abstract: The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.

Abstract: The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.

Abstract: An objective of the present invention is to provide intestinal absorptive antitumor agents with an excellent intestinal absorptive effect by using injectable antitumor agents. In the intestinal absorptive pharmaceutical agents of the present invention, antitumor components that can be used only as injections are supported by hydroxyapatite particles.

Abstract: A vascular repair device includes a tubular graft body and a structural framework having at least two stents connected to the graft body. Stents of the structural framework can each be respectively connected to graft body adjacent the proximal and ends and the support member is shorter than the separation distance therebetween to form a gimbal at least at one end. A first stent is connected along an entirety thereof and a second stent is connected at distal apices thereof. Distal apices of the second stent have radii of curvature smaller than proximal apices. A curved longitudinal support member can be connected to the graft body, the support member being substantially symmetrical with respect to the centerline. The support member can be connected to the graft body independent of the structural framework. At least one of the ends of the support member can have a curved longitudinal extremity.

Abstract: A constrained non-linear approximator for empirical process control is disclosed. The approximator constrains the behavior of the derivative of a subject empirical model without adversely affecting the ability of the model to represent generic non-linear relationships. There are three stages to developing the constrained non-linear approximator. The first stage is the specification of the general shape of the gain trajectory or base non-linear function which is specified graphically, algebraically or generically and is used as the basis for transfer functions used in the second stage. The second stage of the invention is the interconnection of the transfer functions to allow non-linear approximation. The final stage of the invention is the constrained optimization of the model coefficients such that the general shape of the input/output mappings (and their corresponding derivatives) are conserved.

Abstract: A block repair device is used in a Dynamic Random Access Memory (DRAM) having a primary array with a defective cell and a redundant array with a redundant row. The block repair device stores a block repair configuration that determines the dimensions (e.g., the number of rows and columns spanned) of a repair block. Routing circuitry is configured by the stored block repair configuration to output some row and column address bits from received row and column addresses in a selected ratio. Comparison circuitry compares the row and column address bits output by the routing circuitry with the address of the defective cell that defines the repair block. When a match occurs, the comparison circuitry implements a block repair by activating the redundant row and by causing data to be written to or read from the activated redundant row instead of the primary array.

Abstract: The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.

Abstract: A computer method and apparatus control virtual environment cameras based on context. Current context is detected in a subject virtual environment. As a function of detected context, a set of predefined camera views is provided and displayed for user selection. Upon user selection of a camera view from the provided and displayed set of predefined camera views, a camera of the subject virtual environment is updated. The camera view is changed to the user selected camera view. There is ongoing detection of context and indicating of candidate camera views based on context, for user selection and update of the camera view.