Patents Represented by Attorney Jason I. Garbell
  • Patent number: 6673763
    Abstract: The invention relates to a liquid composition comprising dispersed herein solid particles comprising a solid wax matrix, wherein an active is distributed. The invention also relates to particles in the liquid composition and the processes and uses of the composition and the particles.
    Type: Grant
    Filed: September 22, 2000
    Date of Patent: January 6, 2004
    Assignee: Novozymes A/S
    Inventors: Ole Regnar Hansen, Erik Marcussen
  • Patent number: 6663903
    Abstract: The present invention relates to methods for preparing a dough, comprising incorporating into the dough a composition comprising an effective amount of an XET which improves one or more properties of the dough or a baked product obtained from the dough. The present invention also relates to methods for preparing a baked product. The present invention also relates to compositions comprising an effective amount of an XET for improving one or more properties of a dough and/or a baked product obtained from the dough. The present invention further relates to doughs or baked products and to pre-mixes for a dough.
    Type: Grant
    Filed: October 31, 2000
    Date of Patent: December 16, 2003
    Assignee: Novozymes A/S
    Inventor: Ruby Ilum Nielsen
  • Patent number: 6642044
    Abstract: The invention relates to a variant of a parent Termamyl-like a-amylase, which variant has a-amylase activity and exhibits an alteration in at least one of the following properties relative to said parent a-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca2+ dependency and specific activity.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: November 4, 2003
    Assignee: Novozymes A/S
    Inventors: Allan Svendsen, Torben Vedel Borchert, Henrik Bisg{dot over (a)}rd-Frantzen
  • Patent number: 6630342
    Abstract: The present invention provides methods for high-temperature biopreparation of cellulosic fibers by contacting the fibers with pectin-degrading enzymes, preferably thermostable, alkaline, divalent cation-independent pectate lyases, under conditions compatible with scouring and bleaching technologies.
    Type: Grant
    Filed: February 20, 2001
    Date of Patent: October 7, 2003
    Assignee: Novozymes A/S
    Inventors: Niels Erik Krebs Lange, Lars Kongsbak, Martin Shülein, Mads Eskelund Bjørnvad, Philip Anwar Husain
  • Patent number: 6624129
    Abstract: The present invention relates to lipase variants having at least 90% identity to the wild-type lipase derived from Humicola lanuginosa strain DSM 4109 and having a certain distribution of electrically charged amino acids. The present invention also relates to detergents comprising such lipases.
    Type: Grant
    Filed: August 1, 2000
    Date of Patent: September 23, 2003
    Assignee: Novozymes A/S
    Inventors: Kim Borch, Jesper Vind, Allan Svendsen, Dorte Aaby Halkier, Shamkant Anant Patkar, Kirsten Bojsen
  • Patent number: 6602843
    Abstract: This invention relates to an enzyme containing granular composition comprising: a) an enzyme containing core and b) a protective substantially continuous layer or coating encapsulating the core comprising at least 60% of a water soluble compound, having a molecular weight below 500 grams per mole, a pH below 11 and a constant humidity at 20° C. of more than 81%. The invention provides an improved stability of enzymes upon storage.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: August 5, 2003
    Assignee: Novozymes A/S
    Inventor: Erik Kjær Markussen
  • Patent number: 6582942
    Abstract: An immobilized enzyme is prepared for use in organic mediums essentially devoid of free water. An enzyme-containing liquid medium is contacted with a particulate porous carrier which preferably has a particle size of 200-1000 &mgr;m and a surface area of 20-1000 m2/g to adsorb the enzyme on the carrier, and volatile components of the liquid medium contained by the carrier are removed. The carrier may have a hydrophilic surface, and an amount of liquid medium is used to prevent agglomeration of the carrier. Alternatively, the carrier has a hydrophobic surface, and the addition of a hygroscopic substance suppresses agglomeration of the carrier by absorbing excess liquid. The hygroscopic substance may be removed during the removal of volatile components. Contacting of the enzyme-containing liquid and carrier can be in a fluidized bed where immobilization and removing volatile components are conducted simultaneously, or contacting can be in mixer followed by removing volatile components in a fluidized bed.
    Type: Grant
    Filed: August 29, 2000
    Date of Patent: June 24, 2003
    Assignee: Novozymes A/S
    Inventors: Morten Würtz Christensen, Ole Kirk, Christian Pedersen
  • Patent number: 6551636
    Abstract: The present invention provides methods for modifying whey protein preparations to improve their foaming and other functional properties utilizing limited proteolytic hydrolysis. The invention also provides modified whey protein preparations and and food products that comprise them.
    Type: Grant
    Filed: July 23, 1999
    Date of Patent: April 22, 2003
    Assignee: Novozymes A/S
    Inventor: Shengi A. Chen
  • Patent number: 6551635
    Abstract: The present invention relates to a process for producing cheese from enzyme-treated cheese milk, and the use of the resulting produced cheese as ingredient in food products. More particularly, the present invention relates to a process for producing cheese from cheese milk treated with a enzyme selected from the group of phospholipases, in particular phospholipase A1, A2 and B. Also, the present invention relates to a process for stabilizing the fat emulsion of a milk composition, e.g. cream, and the use of such stabilized milk composition, e.g. for the manufacturing of UHT-cream or cream liquor.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: April 22, 2003
    Assignee: Novozymes, A/S
    Inventor: Per Munk Nielsen
  • Patent number: 6548278
    Abstract: The present invention relates to a process for enzymatic hydrolysis of cyclic oligomers of poly(ethylene terephthalate), which process comprises subjecting the cyclic oligomer to the action of one or more lipolytic and/or biopolyester hydrolytic enzyme(s).
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: April 15, 2003
    Assignee: Novozymes A/S
    Inventors: Martin Riegels, Rainhard Koch, Lars Saaby Pedersen, Henrik Lund
  • Patent number: 6544297
    Abstract: The present invention provides methods for single-bath biopreparation and dyeing of cellulosic fibers, which are carried out by contacting the fibers simultaneously or sequentially with a bioscouring enzyme, preferably pectinase, protease, and/or lipase, and a dyeing system, under conditions that do not require emptying the bath or rinsing the fabric between biopreparation and dyeing steps.
    Type: Grant
    Filed: May 24, 2000
    Date of Patent: April 8, 2003
    Assignee: Novozymes, A/S
    Inventors: Jiyin Liu, Brian Condon, Harry Lee Showmaker, III
  • Patent number: 6541207
    Abstract: A method for in vitro construction of a library of recombined homologous polynucleotides from a number of different starting DNA templates and primers by induced template shifts during an polynucleotide synthesis is described, whereby A. extended primers are synthesized by a) denaturing the DNA templates b) annealing primers to the templates, c) extending the said primers by use of a polymerase, d) stop the synthesis, and e) separate the extended primers from the templates, B. a template shift is induced by a) isolating the extended primers from the templates and repeating steps A.b) to A.e) using the extended primers as both primers and templates, or b) repeating steps A.b) to A.e), C. this process is terminated after an appropriate number of cycles of process steps A. and B.a), A. and B.b), or combinations thereof. Optionally the polynucleotides are amplified in a standard PCR reaction with specific primers to selectively amplify homologous polynucleotides of interest.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: April 1, 2003
    Assignee: Novozymes A/S
    Inventors: Jesper Vind, Torben Vedel Borchert
  • Patent number: 6528298
    Abstract: The invention relates to a novel Termamyl-like &agr;-amylase, and Termamyl-like &agr;-amylases comprising mutations in two, three, four, five or six regions/positions. The variants have increased thermostability at acidic pH and/or at low Ca2+ concentrations (relative to the parent).
    Type: Grant
    Filed: April 7, 2000
    Date of Patent: March 4, 2003
    Assignee: Novozymes, A/S
    Inventors: Allan Svendsen, Torben Vedel Borchert, Henrik Bisgard-Frantzen, Helle Outtrup, Bjarne Ronfeldt Nielsen, Vibeke Skovgaard Nielsen, Lisbeth Hedegaard
  • Patent number: 6514739
    Abstract: The inventors have isolated lysophospholipases from Aspergillus (A. niger and A. oryzae) having molecular masses of about 68 kDa and amino acid sequences of 600-604 amino acid residues. The novel lysophospholipases have only a limited homology to known amino acid sequences. The inventors also isolated genes encoding the novel enzymes and cloned them into E. coli strains.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: February 4, 2003
    Inventors: Hiroaki Udagawa, Torben Peter Frandsen, Tom Anton Busk Nielsen, Markus Sakari Kauppinen, Søren Christensen
  • Patent number: 6511837
    Abstract: The present invention relates to lipolytic enzymes and DNA sequences encoding same. More specifically, the present invention relates to the lipolytic enzyme and DNA encoding same isolated from Fusarium culmorum CBS 513.94 and analogues thereof.
    Type: Grant
    Filed: June 26, 2001
    Date of Patent: January 28, 2003
    Assignee: Novozymes A/s
    Inventor: Noriko Tsutsumi
  • Patent number: 6509182
    Abstract: The present invention relates to lipolytic enzymes and DNA sequences encoding same. More specifically, the present invention relates to the lipolytic enzyme and DNA encoding same isolated from Acremonium berkeleyanum CBS 301.38 and analogues thereof.
    Type: Grant
    Filed: June 26, 2001
    Date of Patent: January 21, 2003
    Assignee: Novozymes A/S
    Inventor: Noriko Tsutsumi
  • Patent number: 6506566
    Abstract: The invention relates to a method of identifying enzymes suitable for use in detergents, especially the selection of specific enzyme variants among a large number of such variants created through random mutagenesis.
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: January 14, 2003
    Assignee: Novozymes A/S
    Inventors: Peter Markvardsen, Mads Eskelund Bjornvad, Frank Mikkelsen, Borge Diderichsen
  • Patent number: 6506588
    Abstract: The present invention relates to lipolytic enzymes and DNA sequences encoding same. More specifically, the present invention relates to the lipolytic enzyme and DNA sequences encoding same isolated from Fusarium sulphureum and analogues thereof.
    Type: Grant
    Filed: June 26, 2001
    Date of Patent: January 14, 2003
    Assignee: Novozymes, A/S
    Inventors: Noriko Tsutsumi, Yukiko Sasaki
  • Patent number: 6495357
    Abstract: The present invention relates to a modified enzyme with lipolytic activity, a lipolytic enzime capable of removing a substantial amount of fatty matter a one cycle wash, a DNA sequence encoding said enzymes, a vector comprising said DNA sequence, a host cell harbouring said DNA sequence or said vector, and a process for producing said enzymes with lipolytic activity.
    Type: Grant
    Filed: January 14, 1998
    Date of Patent: December 17, 2002
    Assignee: Novozyme A/S
    Inventors: Claus Crone Fuglsang, Jens Sigurd Okkels, Dorte Aaby Petersen, Shamkant Anant Patkar, Marianne Thellersen, Allan Svendsen, Kim Borch, John C. Royer, Titus Kretzschmar, Torben Halkier, Jesper Vind, Steen Troels Jorgensen
  • Patent number: 6461849
    Abstract: The present invention relates to polypeptides with reduced immune response including reduced allergenicity having one or more amino acid residues being substituted with other amino acid residues and/or having coupled one or more polymeric molecules in the vicinity of the polypeptides metal binding site, a method for preparing modified polypeptides of the invention, the use of the polypeptide for reducing the immunogenicity and allergenicity and compositions comprising the polypeptide.
    Type: Grant
    Filed: October 13, 1999
    Date of Patent: October 8, 2002
    Assignee: Novozymes, A/S
    Inventors: Arne Agerlin Olsen, Claus von der Osten, Kim Vilbour Andersen, Steffen Ernst, Erwin Ludo Roggen