Patents Represented by Law Firm Millen, Raptes & White
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Patent number: 3994050Abstract: A fastening clip for mounting paintings and the like which comprises a piece of spring material, having two substantially opposing pincers which are adapted for clamping something between them, a connecting part extending from the first pincer to the second pincer and including a spring loop, which extends from the second pincer, with the feature that the spring loop is extended in a general direction substantially orthogonal to an imaginary plane in which the pincers move towards and away from each other. Preferably the spring loop is located on one side of the imaginary plane in which the pincers move and a remainder of the connecting part is located on the other side of the imaginary plane so as to lead to one pincer located with regard to the other pincer in such a way that springing open of the spring loop moves the pincers towards one another.The spring clip can be of narrow width, in which case one or more can be clipped onto each edge of a picture or the like.Type: GrantFiled: June 20, 1975Date of Patent: November 30, 1976Inventor: Hans Werner Alfred Bub
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Patent number: 3995023Abstract: Improved allergen-containing extracts are obtained by the extraction of allergy-causing materials, such as pollen and house dust, with hydrophilic aqueous extractants, by pretreating the allergen-containing material with a lipophilic, aqueous extraction liquid. Allergens extracted in the two steps can be combined and formed onto allergen preparations, which can be used both for diagnostic and therapeutic purposes.Type: GrantFiled: December 15, 1975Date of Patent: November 30, 1976Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventors: Otto Nieschulz, Gunther Rudiger, Jurgen Maass
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Patent number: 3994937Abstract: 15.alpha.,16.alpha.-METHYLENE-4-ESTREN-17.beta.-OLS OF THE Formula ##SPC1##Wherein R.sub.1 is lower alkyl, R.sub.2 is hydrogen or an acyl residue, R.sub.3 is hydrogen or a substituted or unsubstituted, saturated or unsaturated monovalent lower aliphatic hydrocarbon, and X is oxygen or the group H,OR.sub.4, wherein R.sub.4 is hydrogen or an acyl residue, have useful anabolic, androgenic, and/or gestagenic activity.Type: GrantFiled: June 28, 1974Date of Patent: November 30, 1976Assignee: Schering AktiengesellschaftInventors: Rudolf Wiechert, Hermann Steinbeck, Walter Elger
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Patent number: 3993759Abstract: 2-Benzoyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline is used as an anthelmintic against cestodes and trematodes, preferably in admixture with a pharmaceutically acceptable carrier.Type: GrantFiled: March 11, 1974Date of Patent: November 23, 1976Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventors: Rolf Pohlke, Friedrich Loebich, Herbert Thomas, Jurgen Thyssen
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Patent number: 3992891Abstract: In a process for recovering the energy from a liquefied gas by evaporation in heat exchange with a cycle medium which is simultaneously cooled, said cycle medium being thereafter compressed, heated, subjected to engine expansion and recovered in a cyclical manner, wherein the improvement comprises operating the cycle so that the cycle medium remains in the gaseous phase throughout the entire cycle.Type: GrantFiled: February 18, 1975Date of Patent: November 23, 1976Assignee: Linde AktiengesellschaftInventor: Anton Pocrnja
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Patent number: 3993760Abstract: (-)-2-Benzoyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline is prepared by benzoylation of (-)-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline, or cyclization of a compound of the formula ##SPC1##Wherein X is F, Cl, Br, I or O-tosyl and which has the optical configuration of the final product, or cyclization of a compound of the formula ##SPC2## wherein Y is OH, alkoxy, F, Cl, Br or I under HY-removing reaction conditions and which has the optical configuration of the final product, which is an anthelmintic.Type: GrantFiled: June 21, 1974Date of Patent: November 23, 1976Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventors: Rolf Pohlke, Friedrich Loebich, Jurgen Seubert, Herbert Thomas, Peter Andrews
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Patent number: 3992443Abstract: Alcohols, preferably ethoxylated alcohols, are carboxymethylated by reacting a mixture thereof and a salt of chloroacetic acid with an alkali hydroxide.Type: GrantFiled: April 15, 1975Date of Patent: November 16, 1976Assignee: Chemische Werke Huls AktiengesellschaftInventor: Hermann Springmann
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Patent number: 3991579Abstract: A self-advancing chock for supporting the roof of the gallery of a mine near the working face utilizing one or more lever arms articulated to the forward portion of a base (nearer the working face) and to the rear portion of a roof-supporting cap. The cap has sufficient area to cover the other elements of the chock in all positions of the lever arms and may have a slightly concave upper surface. If two lever arms are used they may be rigidly or flexibly interconnected and the cap may be in two sections for use with sloping or irregular roof areas. The base element may also be in two sections.Type: GrantFiled: December 2, 1974Date of Patent: November 16, 1976Assignee: Mines de Potasse d'Alsace S.A.Inventor: Pierre Deffontaine
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Patent number: 3992386Abstract: Phenoxyacetic acids of the formula ##SPC1##Wherein R.sub.1 is H or alkyl of 1-4 carbon atoms; R.sub.2 is H, or when R.sub.4 is Q, also alkyl of 1-4 carbon atoms; R.sub.3 is methyl, phenyl or chlorophenyl; and R.sub.4 is piperidino, isoindolino, 1,2,3,4-tetrahydroquinolino, 1-R.sub.5 -1,2,3,4-tetrahydro-4-quinolyl, 4-piperidinophenyl, 4-piperidinophenoxy, 1-pyrryl, or Q, wherein R.sub.5 is H or alkyl of 1-4 carbon atoms; and Q is 4-oxo-1,2,3,4-tetrahydroquinolino, 4-hydroxy-1,2,3,4-tetrahydroquinolino, 4-chromanyl, 4-thiochromanyl or 1-phenyl-1,2,3,4-tetrahydro-4-quinolyl; and the salts thereof, possess cholesterol level-lowering activity.Type: GrantFiled: March 8, 1974Date of Patent: November 16, 1976Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventors: Erich Schacht, Werner Mehrhof, Herbert Nowak, Zdenek Simane, Detlev Kayser
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Patent number: 3992468Abstract: Process for hydrodealkylating alkylaromatic hydrocarbons using a catalyst comprising at least two metals deposited on a carrier, a first of these two metals being selected either from the group consisting of cobalt, ruthenium, osmium, palladium, rhodium, iridium and platinum or from the group consisting of chromium, molybdenum, tungsten and manganese, and the second of these two metals being selected from zinc, cadmium, gallium, indium, thallium, manganese, copper, silver, gold, yttrium, titanium, niobium, tentalum, chromium, molybdenum, tungsten, rhenium, germanium, tin and lead.Type: GrantFiled: February 24, 1975Date of Patent: November 16, 1976Assignee: Institut Francais du Petrole, des Carburants et Lubrifiants et Entreprise de Recherches et d'Activities Petrolieres ElfInventors: Jean Cosyns, Bernard Juguin, Jean-Francois Le Page, Jean Miquel
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Patent number: 3992465Abstract: Process for producing aromatic hydrocarbons, particularly benzene and/or toluene from a feed charge containing saturated and unsaturated hydrocarbons, by catalytic treatment of said charge with hydrogen, fractionation of the resulting product to separate a fraction containing benzene and/or toluene, extractive distillation of at least one aromatic hydrocarbon in a column, by means of an extraction solvent from which said hydrocarbon is subsequently separated, and recycling to the reaction zone of at least one portion of the products recovered at the top of said extractive distillation column and containing essentially C.sub.6 and C.sub.7 saturated hydrocarbons.Type: GrantFiled: January 2, 1974Date of Patent: November 16, 1976Assignee: Institut Francais du Petrole, des Carburants et Lubrifiants et Entreprise de Recherches et d'Activities Petrolieres ElfInventors: Bernard Juguin, Georges Cohen, Paul Mikitenko
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Patent number: 3992374Abstract: Amino-substituted nitroimidazolyl-methyleneaminoimidazolidinones of the formula ##SPC1##Wherein --NR.sub.2 R.sub.3 is dialkylamino or heterocyclic amino, and the physiologically acceptable salts thereof, possess antitrichomonial activity.Type: GrantFiled: June 28, 1974Date of Patent: November 16, 1976Assignee: Schering AktiengesellschaftInventors: Clemens Rufer, Hans-Joachim Kessler
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Patent number: 3990963Abstract: Used lubricating oils are first heated to 200.degree.-500.degree. C, optionally with added steam, and then filtered through a membrane such as an ultra-filtration membrane. The latter has preferably a cut range of from 5,000 to 300,000.Type: GrantFiled: February 28, 1975Date of Patent: November 9, 1976Assignee: Institut Francais du Petrole, des Carburants et Lubrifiants et Entreprise de Recherches et d'Activities Petrollieres ElfInventors: Francois Audibert, Maurice Born, Daniel Defives, Xavier Marze
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Patent number: 3990956Abstract: A process for the preparation of keto steroids by electrochemical reduction, comprising electrolyzing a .alpha.,.beta.-unsaturated keto steroid in a nonaqueous nitrogen-containing solvent containing an electrolyte which is at least one of:A. a quaternary ammonium salt of the general formula NR.sub.1 R.sub.2 R.sub.3 R.sub.4 X, wherein R.sub.1.sub.+4 represent an alkyl, aryl, or aralkyl residue, orB. an alkali or alkaline earth salt of X, wherein X is sufficient anion for charge equalization and represents halogen, tetrafluoborate, sulfate, perchlorate, alcoholate, arylsulfonate or alkylsulfonate.Type: GrantFiled: January 14, 1975Date of Patent: November 9, 1976Assignee: Schering AktiengesellschaftInventor: Klaus Junghans
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Patent number: 3989833Abstract: Adenine derivatives of the formula ##SPC1##Wherein R is phenyl or thienyl, and the physiologically acceptable acid addition salts thereof, possess, with good compatibility, cardio-active properties and are produced by the reaction of a purine derivative of the formula ##SPC2##Wherein X is F, Cl, Br, I, SR.sub.1, SOR.sub.1, SO.sub.2 R.sub.1 or OSi(CH.sub.3).sub.3, R.sub.1 being alkyl of 1-4 carbon atoms, phenyl or benzyl, with an amine of the formula ##SPC3##Wherein R has the values given above, or a salt thereof.Type: GrantFiled: November 4, 1974Date of Patent: November 2, 1976Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventors: Rochus Jonas, Werner Mehrhof, Karl Heinz Becker, Hans-Jochen Schliep
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Patent number: 3989818Abstract: Influenza virus is purified, fractionated or concentrated in an aqueous medium, using a linear filamentary non-charged polymer, preferably polyethylene glycol, as an insolubilising agent, at a concentration not exceeding 5% by weight. Impurities and large virus particles can be fractionated off at PEG concentrations of say up to 1%. Phase separation is achieved most readily when assisted by ultra-centrifugation at low temperature between 0.degree. and 6.degree. C. Precipitation of the virus from dispersions of comparatively high concentration (say 600 HA units or more per ml.) results in intimately aggregated virus particles, which are easier to further purify, and which result in an improved vaccine. Novel concenrates of globular influenza virus are also described.Type: GrantFiled: October 4, 1974Date of Patent: November 2, 1976Assignee: South African Inventions Development CorporationInventor: Alfred Polson
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Patent number: 3988468Abstract: 7-Methoxy-6-thiatetracyclines of the formula ##SPC1##Wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 each are H or alkyl of 1 to 4 carbon atoms, and the physiologically acceptable acid addition salts thereof.Type: GrantFiled: July 30, 1975Date of Patent: October 26, 1976Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventors: Werner Rogalski, Richard Kirchlechner, Juergen Seubert, Rudolf Gottschlich, Walter Hameister, Rolf Bergmann, Helmut Wahlig
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Patent number: 3986841Abstract: Apparatus for the continuous production of saturated aliphatic dicarboxylic acids by the catalyzed nitric acid oxidation of the corresponding cycloalkanols and cycloalkanones with recirculation of the reaction sludge and the reaction gases, which comprises cooling the reaction sludge by passing it through the tubes of a multiple tube heat exchanger, separating the reaction gases downstream of the heat exchanger, and dispersing the recycled portion of the reaction gases in the reaction sludge upstream of the heat exchanger, in a volume amount 0.1 to 2.0 times the volume of the reaction sludge circulating per unit time and in a pressure ratio of initial gas pressure to pressure in the circulation reactor at the gas feed point of (x + 0.25) : x to (x + 1.5) : x, wherein x is the pressure at the gas feed point, to form a homogeneously dispersed three-phase mixture of the recycled reaction gases in the reaction sludge in the tubes of the heat exchanger.Type: GrantFiled: January 29, 1975Date of Patent: October 19, 1976Assignee: Chemische Werke Huls AktiengesellschaftInventors: Gerhard Hellemanns, Hermann Rohl, Peter Hegenberg, Werner Eversmann
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Patent number: 3987099Abstract: A process for the catalytic hydrogenation of dodecanedioic acid dinitrile to the corresponding primary amine employing a hydrogenation catalyst which comprises 5-35% by weight of at least one of catalytically active cobalt and nickel as the active component supported on one or more oxides of aluminum, silicon, titanium and iron, wherein the specific surface area of the support material is 0.01-1.2m.sup.2 /g., the pore volume is 0.05-0.4 ml./g., the annealing loss is less than 0.1% and the extractable alkalinity of the support is 0.08-20% by weight of the support. Sufficient alkali is present in the hydrogenation diluent to ensure that the desired alkali concentration remains on the catalyst surface, thereby extending the useful life of the catalyst.Type: GrantFiled: October 22, 1974Date of Patent: October 19, 1976Assignee: Chemische Werke Huls AktiengesellschaftInventors: Gunter Hockele, Gerhard Ludwig
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Patent number: 3987159Abstract: Stable preparations of sensitized erythrocytes are provided by simultaneously admixing washed erythrocytes in a buffered aqueous solution of glutaraldehyde, antigen or antigen-protein conjugate and formaldehyde. After washing, the separated sensitized erythrocytes can be lyophilized and thereby become stable at room temperature.Type: GrantFiled: March 1, 1974Date of Patent: October 19, 1976Assignee: Schering AktiengesellschaftInventors: Jurgen Spona, Michael Topert