Patents Represented by Law Firm Millen, Raptes & White
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Patent number: 3985881Abstract: Novel isoquinoline derivatives of the formula ##SPC1##Wherein R.sub.1 is H or, together with R.sub.2, a C--N bond; R.sub.2 is H, R.sub.8 or, together with R.sub.1, a C--N bond; R.sub.3 is H, methyl or ethyl; R.sub.4 and R.sub.5 each are H or collectively a C--C bond; and R.sub.6 and R.sub.7 each are H or methoxy; R.sub.8 being acyl of 1-10 carbon atoms or alkyl of 1-17 carbon atoms optionally mono- or polysubstituted by phenyl, OH, ArCOO--, ArCONH--, piperidino, 3,4-dehydropiperidino, morpholino, carboxy, carbomethoxy and/or carbethoxy, Ar being 3,4,5-trimethoxyphenyl; and the physiologically acceptable acid addition salts and quaternary ammonium salts thereof, have cardiovascular activity and can be prepared by acylating a corresponding primary amine lacking the COAr group with 3,4,5-trimethoxybenzoic acid or a functional derivative thereof.Type: GrantFiled: December 9, 1974Date of Patent: October 12, 1976Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventors: Werner Mehrhof, Rolf Pohlke, Karl Heinz Becker, Hans-Jochen Schliep
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Patent number: 3985711Abstract: A dicarboxylic compound complying with one of the general formulae: ##SPC1##In which R is a divalent radical selected from the aliphatic, alicyclic and aromatic radicals, the aliphatic containing 1-20 carbon atoms and the other containing from 5 to 20 carbon atoms, R.sup.1 is selected from the hydrogen atom and the alkyl and cycloalkyl groups containing from 1 to 10 carbon atoms and R.sup.2 is selected from the alkyl and cycloalkyl groups containing from 1 to 10 carbon atoms, the polyester resins derived therefrom being usable as enamelling composition, particularly for coating metal wires.Type: GrantFiled: March 5, 1975Date of Patent: October 12, 1976Assignee: Institut Francais du Petrole, des Carburants et Lubrifiants et Entreprise de Recherches et d'Activities Petrolieres ElfInventors: Choua Cohen, Bruno Durif-Varambon, Robert Salle, Bernard Sillion
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Patent number: 3984014Abstract: A platform is mounted in the doorway of a van so that it can be rotated from an upstanding stored position to a horizontal loading position level with the vehicle floor. From this point, it can be lowered to the ground. A particular linkage and cable-and-drum combination is disclosed which is very compact in the stored position. The unit is fully automated in that: (1)a switch, internal of the vehicle, can be actuated to mechanically open the vehicle doors and rotate the platform from the storage to the loading position or vice-versa; (2)a switch, accessible from the platform, can be actuated to lower or raise the platform between the loading and ground positions; and (3)a switch, external of the vehicle, can be actuated to open the doors and move the platform from the stored to the ground positions or vice-versa.Type: GrantFiled: June 24, 1974Date of Patent: October 5, 1976Inventor: Leo Pohl
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Patent number: 3984454Abstract: Prostanoic acid esters of the formulaPG -- CH.sub.2 -- X -- Ywherein PG is the prostanoyloxy radical of a prostaglandin, X is a carbon-carbon single bond, carbonyl or carbonyloxy, and Y is substituted phenyl are easily crystallized compounds at least as active as the unesterified prostanoic acid and useful for the purification of the parent prostaglandin are prepared by reacting, in the presence of an agent which splits off hydrogen halide, the unesterified prostaglandin with a halide of the formula Hal--CH.sub.2 --X--Y, wherein Hal is a halogen atom and X and Y have the values given above.Type: GrantFiled: May 2, 1974Date of Patent: October 5, 1976Assignee: Schering AktiengesellschaftInventors: Werner Skuballa, Bernd Raduchel, Helmut Vorbruggen, Walter Elger, Olaf Loge, Wolfgang Losert
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Patent number: 3983104Abstract: Novel N.sup.6 -substituted adenosines and a novel process for the preparation of N.sup.6 -substituted adenosines from 6-trialkylsiloxypurine derivatives. The derivatives are reacted in the presence of a tertiary base or a Lewis acid with ammonia or an amine of the formula HNR.sub.1 R.sub.2, wherein R.sub.1 and R.sub.2 are the same or different represent hydrogen, alkyl of 1-6 carbon atoms, aralkyl or 7 to 10 carbon atoms unsubstituted or substituted with hydroxy or alkoxy with 1-4 carbon atoms, aryl unsubstituted or substituted with hydroxy or alkoxy with 1 to 4 carbon atoms, a heterocyclic ring of 4 to 7 members, containing a total of 1-3 hetero atoms which can be nitrogen, oxygen or sulfur; or when R.sub.1 is hydrogen R.sub.Type: GrantFiled: October 6, 1972Date of Patent: September 28, 1976Assignee: Schering AktiengesellschaftInventor: Helmut Vorbruggen
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Patent number: 3982747Abstract: The invention relates to a ski pole and handle comprising a handstrap releasible from the handle to prevent injury to a skier. The handstrap comprises plate means adapted to be inserted in slot means of the handle. The plate means are retained in the handle by a pressure adjustable release means. The release means can comprise spring-biased ball means engaging a hole in the plate means. Biasing pressure of the spring means is adjustable by means of an element engaging said spring means and which is threaded and adjustable in the handle.Type: GrantFiled: April 11, 1975Date of Patent: September 28, 1976Assignee: Joseph Stamm KGInventor: Hubert Schweinsberg
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Patent number: 3983183Abstract: Low molecular weight polybutadiene, polyisoprene and other hydrocarbon polymers having a high vinyl and a low 1,4-trans-double bond content, which are useful in varnishes and impregnating compositions, are produced employing as catalyst system (a) a cobalt compound; (b) a halogen-containing organoaluminum compound; and (c) an organic phosphite of the formula PR.sub.1, R.sub.2, R.sub.3 wherein R.sub.1, R.sub.2 and R.sub.3 are alkoxy, alkenyloxy or monocyclic aryloxy; and optionally (d) an H-acidic compound, e.g., water.Type: GrantFiled: December 9, 1974Date of Patent: September 28, 1976Assignee: Chemische Werke Huls AktiengesellschaftInventor: Wolfgang Kampf
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Patent number: 3981849Abstract: High molecular weight, low density copolymers of ethylene and propylene and/or butene-1 are prepared by a low pressure liquid phase polymerization process using a titanium halide - organoaluminum catalyst in a polymerization solvent containing butene-2. Consistently comparable ethylene copolymers can be obtained from monomer mixtures of varying composition.Type: GrantFiled: October 2, 1974Date of Patent: September 21, 1976Assignee: Chemische Werke Huls AktiengesellschaftInventors: Albert Frese, Fritz Baxmann, Walter Dittmann
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Patent number: 3981887Abstract: Sulfoxides and sulfones of the formula ##SPC1##Wherein R.sub.1 is COOH, COOR.sub.4, CH.sub.2 OH, or CH.sub.2 OR.sub.5 ; R.sub.2 is CH.sub.3 or C.sub.2 H.sub.5 ; R.sub.3 is H, F, Cl, or Br; R.sub.4 is alkyl of 1-8 carbon atoms; R.sub.5 is alkanoyl of 2-4 carbon atoms; one of the Y groups is SO or SO.sub.2 and the other Y group is CH.sub.2, O, S, SO, or SO.sub.2 ; and the physiologically acceptable salts thereof, which compounds possess anti-inflammatory activity, can be produced by converting in a compound of the formula ##SPC2##Wherein X is a group convertible into the group --CHR.sub.1 R.sub.2 wherein R.sub.1, R.sub.2, R.sub.3, and Y have the values given above, the group X into the group --CHR.sub.1 R.sub.3.Type: GrantFiled: July 31, 1974Date of Patent: September 21, 1976Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventors: Joachim Gante, Hans-Adolf Kurmeier, Werner Mehrhof, Albrecht Wild
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Patent number: 3981398Abstract: The apparatus for use especially in treatment of emergency medical conditions. The apparatus comprises a briefcase or the like containing a holder, preferably a tray-like receptacle with recesses containing a drug or instrument or other article in each recess, in combination with preferably a plurality of masks. Each mask is adapted to mask the holder and its contents except for openings in the mask which expose same, but not all of the articles in the holder, the exposed articles being appropriate to a particular mode of treatment of the person, the mask being marked to indicate that particular treatment at least. Preferably, the mask also carried step-by-step instructions to confirm diagnosis and carry out appropriate treatment, with the articles located in sequential order related to the next.Type: GrantFiled: January 29, 1975Date of Patent: September 21, 1976Assignee: Hendrik Lukas PienaarInventor: Pieter Nico Sinclair Boshoff
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Patent number: 3981967Abstract: An improved process for the recovery of mercury from exhausted mercury-containing catalyst by heating the inactive catalyst at 270.degree.-600.degree.C. while passing a carrier gas therethrough, which comprises pretreating the exhausted catalyst with chlorine.Type: GrantFiled: November 3, 1971Date of Patent: September 21, 1976Assignee: Chemische Werke Huls AktiengesellschaftInventors: Heinz Maiwald, Gunter Hockele, Hermann Sauer
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Patent number: 3981453Abstract: A method for segregating bark and/or foliage from wood chips and/or twigs in a mixture of such components is provided. The method includes three essential steps. The first step comprises conditioning a pile of such mixture by periodically sprinkling the pile with water during storage. The second step comprises vigorously agitating the conditioned mixture with sufficient water, and for sufficient time to break bonded bark from the wood chips and the twigs and to comminute the bark. The third step comprises wet screening the agitated mixture thereby separating effluent bark and foliage from the wood chips and/or twigs in the mixture. An additional step includes dewatering the effluent bark and foliage, thereby to recover screened out solids materials. This method can be operated successfully on either a batch or a continuous basis without any serious effect on the reduction of pulp quality.Type: GrantFiled: November 29, 1974Date of Patent: September 21, 1976Assignee: Pulp and Paper Research Institute of CanadaInventors: Robin Wilfrid Berlyn, James David Hutchinson
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Patent number: 3980795Abstract: Pyrazolidinones of the formula ##SPC1##Wherein R is a phenyl, phenoxy or a corresponding group monosubstituted or polysubstituted by one or more of F, Cl and Br possess anti-inflammatory activity.Type: GrantFiled: November 5, 1975Date of Patent: September 14, 1976Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventors: Joachim Gante, Hans-Adolf Kurmeier, Erich Schacht, Werner Mehrhof, Albrecht Wild
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Patent number: 3980448Abstract: This invention relates to gasoline compositions containing additives which are reaction products of a maleic anhydride of the formula ##EQU1## with a linear polyamine of the formulaH.sub.2 N--(CH.sub.2).sub.n -- NH].sub.m R'in which R.sub.1 and R.sub.2 are selected from the group consisting of a hydrogen atom and a monovalent hydrocarbon radical of 1 - 30 carbon atoms, R' is a monovalent aliphatic hydrocarbon radical having 6 - 30 carbon atoms, n is an integer from 3 to 10 and m is an integer from 1 to 10.Type: GrantFiled: May 2, 1973Date of Patent: September 14, 1976Assignee: Institut Francais du Petrole, des Carburants et Lubrifiants et Entreprise de Recherches et d'Activities Petrolieres ElfInventors: Bernard Haemmerle, Bernard Sillion, Gabriel De Gaudemaris
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Patent number: 3980727Abstract: Toluene and poly-methyl benzene hydrocarbons are reacted in the presence of an improved catalyst containing a group VIII noble metal. The catalyst is obtained by admixing a catalyst carrier with a Group VIII noble metal or compound thereof and with a hydrocarbyl aluminum halide. Sulfur may be present. The yield and selectivity are substantially improved as compared to conventional catalysts.Type: GrantFiled: March 19, 1975Date of Patent: September 14, 1976Assignee: Institut Francais du Petrole, des Carburants et Lubrifiants et Entreprise de Recherches et d'Activities Petrolieres ElfInventors: Christian Marcilly, Germain Martino, Jean-Pierre Franck
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Patent number: 3980797Abstract: Hexahydro-diazepino-indoles of the formula ##SPC1##Wherein R.sup.1 is H, F, Cl, CF.sub.3, alkyl or alkoxy each of 1 to 3 carbon atoms; R.sup.2 is H, alkyl or cycloalkyl or alkenyl each of up to 6 carbon atoms, or alkyl of up to 6 carbon atoms substituted by oxo oxygen and/or amino or alkylated amino of 2 to 6 carbon atoms and/or aryl of 6 to 8 carbon atoms; and Z is 0 or (H,H), and physiologically acceptable acid addition salts thereof, possess CNS depressant activity.Type: GrantFiled: June 13, 1975Date of Patent: September 14, 1976Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventors: Rochus Jonas, Helmut Muller-Calgan, Hans-Jochen Schliep
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Patent number: 3980721Abstract: New catalyst, particularly suitable for dehydrogenating saturated hydrocarbons, which contains alumina, at least one metal selected from molybdenum, tungsten and rhenium and at least one metal selected from gallium, indium, thallium, germanium, tin, lead, antimony and bismuth, said catalyst having a specific surface from 20 to 150 m.sup.2 /g and a neutralization heat by ammonia absorption at 320.degree.C under 300 mm Hg lower than 10 calories per gram.Type: GrantFiled: April 3, 1975Date of Patent: September 14, 1976Assignee: Institut Francaise du Petrole, des Carburants et Lubrifiants et Entreprise de Recherches et d'Activites Petrolieres ElfInventors: Bernard Juguin, Jean-Francois Le Page
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Patent number: 3980730Abstract: Organic compounds of the formula:[(H.sub.3.sub.-n X.sub.n)C - CO.sub.2 M (CO).sub.m (R).sub.p (L).sub.q ].sub.rin which X is a halogen atom, at least one X being fluorine, M is molybdenum or tungsten, R is a hydride ion or a hydrocarbon group, L is a Lewis base and m, n, p, q and r are integers, are manufactured from fluoracetic esters and molybdenum or tungsten carbonyl compounds. They are useful as catalysts for polymerizing or co-polymerizing unsaturated compounds such as butadiene.Type: GrantFiled: January 9, 1975Date of Patent: September 14, 1976Assignee: Institut Francais du Petrole, des Carburants et Lubrifiants et Entreprise de Recherches et d'Activities Petrolieres ElfInventors: Francois Dawans, Emmanuel Goldenberg
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Patent number: 3976701Abstract: 6,9-Oxido-9,10-seco-1,3,5(10),6,8,14-estrahexaenes, useful as intermediates in the total synthesis of steroids, of the formula ##SPC1##Wherein n is 1 or 2, R.sub.1 is lower-alkyl, R.sub.2, R.sub. 3 and R.sub.4 are H, alkoxy or acyloxy, X is a free or ketalized keto or free, esterified or etherified hydroxymethylene, are produced by the cyclization, with an acid catalyst, of a 9,10-secoestrane of the formula ##SPC2##Wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, X and n have the values given above, and Q is carbonyl or dialkoxymethylene. Hydrogenation produces the corresponding 6,9-oxido-9,10-seco-1,3,5(10)-estratrienes and 9-oxy-9,10-seco-1,3,5(10)-estratrienes.Type: GrantFiled: October 24, 1973Date of Patent: August 24, 1976Assignee: Schering AktiengesellschaftInventors: Ulrich Eder, Gregor Haffer, Jurgen Ruppert, Gerhard Sauer, Rudolf Wiechert
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Patent number: 3976626Abstract: Binders for coating compositions are produced by an elevated temperature, aqueous phase polymerization, in the presence of an anionic emulsifier, polyethylene oxide and peroxydisulfate, of a monomer mixture consisting by weight of 10-85% vinyl aromatic component, which may be partially replaced by 0-20% of acrylonitrile, 15-90% by weight of diolefin component and up to 6% each of .beta.-unsaturated carboxylic acid or an amide thereof or a mixture thereof, characterized by employing a starting reaction mixture containing 0.05-0.5% of an anionic sulfonate or sulfate emulsifier; 0.5-5% of a polyethylene oxide having an average molecular weight of between 300 and 4,000; and 0.5-2% of a water-soluble peroxydisulfate; and, after a monomer conversion of between 15 and 35% by weight, adding to the reaction mixture another 0.2-1.5% of an anionic sulfonate or sulfate emulsifier.Type: GrantFiled: March 28, 1975Date of Patent: August 24, 1976Assignee: Chemische Werke Huls AktiengesellschaftInventor: Ulrich Turck