Patents Represented by Attorney, Agent or Law Firm Patrick M. Ryan
  • UV-absorbers for ophthalmic lens materials
    Patent number: 8043607
    Abstract: Dihydroxybenzotriazole UV absorbing compounds that are particularly useful in ophthalmic devices are disclosed.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: October 25, 2011
    Assignee: Novartis AG
    Inventor: David L. Jinkerson
  • Method of treating ocular allergy
    Patent number: 8034839
    Abstract: The topical use of 5,6,7-trihydroxyheptanoic acid and analogs alone or in combination with histamine antagonists and/or mast cell stabilizers is disclosed for the treatment of ocular allergy.
    Type: Grant
    Filed: February 8, 2010
    Date of Patent: October 11, 2011
    Assignee: Alcon Research, Ltd.
    Inventors: Peter G. Klimko, Clay Beauregard
  • Olopatadine formulations for topical nasal administration
    Patent number: 7977376
    Abstract: Topical formulations of olopatadine for treatment of allergic or inflammatory disorders of the nose are disclosed. The aqueous formulations contain approximately 0.6% (w/v) of olopatadine.
    Type: Grant
    Filed: February 7, 2007
    Date of Patent: July 12, 2011
    Assignee: Novartis AG
    Inventors: Onkar N. Singh, G. Michael Wall, Rajni Jani, Masood A. Chowhan, Wesley Wehsin Han
  • UV-absorbers for ophthalmic lens materials
    Patent number: 7947849
    Abstract: UV absorbing monomers that are particularly useful in ophthalmic devices are disclosed.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: May 24, 2011
    Assignee: Alcon, Inc.
    Inventor: Walter R. Laredo
  • Method of treating dry eye disorders and uveitis
    Patent number: 7923471
    Abstract: The topical use of 5,6,7-trihydroxyheptanoic acid and analogs are disclosed for the treatment of dry eye disorders and uveitis.
    Type: Grant
    Filed: November 7, 2005
    Date of Patent: April 12, 2011
    Assignee: Alcon, Inc.
    Inventors: Peter G. Klimko, Mark R. Hellberg, Daniel A. Gamache
  • UV-absorbers for ophthalmic lens materials
    Patent number: 7909458
    Abstract: 1,4-disubstituted-1,2,3-triazole UV absorbing monomers are disclosed. The UV absorbers are particularly suitable for use in intraocular lens materials.
    Type: Grant
    Filed: April 29, 2008
    Date of Patent: March 22, 2011
    Assignee: Alcon, Inc.
    Inventor: Douglas C. Schlueter
  • 3,6-substituted imidazol[1,2-b]pyridazine analogs for treating allergic and inflammatory diseases
    Patent number: 7906512
    Abstract: Methods for treating an allergic or inflammatory disease or other Syk-mediated disease or Syk-mediated condition characterized by administering a composition which contains a therapeutically effective amount of a 3,6-substituted imidazol[1,2-b]pyridazine compound.
    Type: Grant
    Filed: March 10, 2010
    Date of Patent: March 15, 2011
    Assignee: Alcon, Inc.
    Inventors: Mark R. Hellberg, Steven T. Miller, Andrew Rusinko
  • Ophthalmic and otorhinolaryngological device materials
    Patent number: 7888403
    Abstract: Disclosed are soft, high refractive index, acrylic device materials. The materials comprise di-block or tri-block macromers containing hydrophilic side-chains. The materials have improved glistening resistance.
    Type: Grant
    Filed: October 3, 2008
    Date of Patent: February 15, 2011
    Assignee: Alcon, Inc.
    Inventor: Douglas C. Schlueter
  • Topical ophthalmic or otic solution formulations containing moxifloxacin hydrochloride and dexamethasone phosphate
    Patent number: 7888370
    Abstract: Topical ophthalmic and otic solution compositions of moxifloxacin and dexamethasone phosphate are disclosed.
    Type: Grant
    Filed: November 24, 2008
    Date of Patent: February 15, 2011
    Assignee: Alcon Research, Ltd.
    Inventors: Onkar N. Singh, Suresh C. Dixit, Michael Wall
  • UV-absorbers for ophthalmic lens materials
    Patent number: 7884228
    Abstract: UV absorbing monomers that are particularly useful in ophthalmic devices are disclosed.
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: February 8, 2011
    Assignee: Alcon, Inc.
    Inventor: Walter R. Laredo
  • Methacrylic materials suitable for ophthalmic and otorhinolaryngological devices
    Patent number: 7858672
    Abstract: Disclosed are soft, high refractive index, methacrylic device materials. The materials contain an ethoxylate monomer to reduce glistenings and a long-chain alkyl methacrylate monomer for softening.
    Type: Grant
    Filed: October 1, 2008
    Date of Patent: December 28, 2010
    Assignee: Alcon, Inc.
    Inventor: Walter R. Laredo
  • Ophthalmic and otorhinolaryngological device materials containing phenylene-siloxane macromers
    Patent number: 7847046
    Abstract: Disclosed are soft, high refractive index, acrylic device materials having improved strength. The materials contain a phenylene-siloxane macromer.
    Type: Grant
    Filed: April 29, 2008
    Date of Patent: December 7, 2010
    Assignee: Alcon, Inc.
    Inventors: Douglas C. Schlueter, David L. Jinkerson
  • Topical nepafenac formulations
    Patent number: 7834059
    Abstract: Topical suspension compositions of nepafenac are disclosed. The compositions are especially suitable for topical ophthalmic administration.
    Type: Grant
    Filed: December 2, 2005
    Date of Patent: November 16, 2010
    Assignee: Alcon, Inc.
    Inventor: Warren Wong
  • UV-absorbers for ophthalmic lens materials
    Patent number: 7803359
    Abstract: UV absorbing compounds that are particularly useful in ophthalmic devices are disclosed.
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: September 28, 2010
    Assignee: Alcon, Inc.
    Inventors: David L. Jinkerson, Joseph I. Weinschenk, III, W. Dennis Dean
  • 5-substituted 2-aminopyridine analogs for treating allergic and inflammatory diseases
    Patent number: 7799778
    Abstract: Methods for treating an allergic or inflammatory disease or other Syk-mediated disease or Syk-mediated condition characterized by administering a composition which contains a therapeutically effective amount of a 5-substituted 2-aminopyridine compound.
    Type: Grant
    Filed: January 12, 2006
    Date of Patent: September 21, 2010
    Assignee: Alcon, Inc.
    Inventors: Mark R. Hellberg, Steven T. Miller, Andrew Rusinko
  • Ophthalmic and otorhinolaryngological device materials
    Patent number: 7799845
    Abstract: Disclosed are soft, high refractive index, acrylic device materials. The materials comprise di-block or tri-block macromers containing a hydrophilic block in the polymer backbone. The materials have improved glistening resistance.
    Type: Grant
    Filed: October 3, 2008
    Date of Patent: September 21, 2010
    Assignee: Alcon, Inc.
    Inventor: Douglas C. Schlueter
  • 1-alkyl-3-aminoindazoles
    Patent number: 7799930
    Abstract: Methods of making 1-alkylindazoles are described. The methods involve reacting a 2-alkylaminobenzonitrile with a nitrosating agent followed by reduction-cyclization of the resulting nitrosamine to form a 1-alkyl-3-aminoindazole. The 1-alkyl-3-aminoindazole can be deaminated to form a 1-alkylindazole which ultimately can be used to form desired indazoles which are preferably pharmaceutically active products. The process of the present invention further permits the formation of enantiomerically enriched or pure indazoles such as aminoalkyl indazoles.
    Type: Grant
    Filed: February 10, 2009
    Date of Patent: September 21, 2010
    Assignee: Alcon, Inc.
    Inventors: Pete Delgado, Raymond E. Conrow, W. Dennis Dean
  • High refractive index ophthalmic device materials
    Patent number: 7790825
    Abstract: High refractive index copolymers suitable for use in ophthalmic devices are disclosed. The copolymers comprise a single aryl hydrophobic monomer as a device forming monomer. In addition, the copolymers comprise a non-polymerizable block copolymer surfactant. The copolymers have a reduced tendency to form glistenings when stored in water at physiological temperatures.
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: September 7, 2010
    Assignee: Alcon, Inc.
    Inventors: Chance Lehman, Charles Freeman
  • High refractive index ophthalmic device materials
    Patent number: 7790824
    Abstract: High refractive index copolymers suitable for use in ophthalmic devices are disclosed. The copolymers comprise two or more aryl hydrophobic monomers and a non-polymerizable propylene oxide-ethylene oxide-propylene oxide block copolymer surfactant having a molecular weight of approximately 3600 and approximately 40% ethylene oxide units by weight. The copolymers have a reduced tendency to form glistenings when stored in water at physiological temperatures compared to similar copolymers lacking the non-polymerizable surfactant.
    Type: Grant
    Filed: July 24, 2008
    Date of Patent: September 7, 2010
    Assignee: Alcon, Inc.
    Inventor: Charles Freeman
  • Ophthalmic lens materials containing chromophores that absorb both UV and short wavelength visible light
    Patent number: 7781571
    Abstract: Chromophores that absorb both UV and short wavelength visible light are disclosed. The chromophores are particularly suitable for use in intraocular lens materials.
    Type: Grant
    Filed: August 7, 2008
    Date of Patent: August 24, 2010
    Assignee: Alcon, Inc.
    Inventors: Joseph I. Weinschenk, III, Douglas C. Schlueter, David L. Jinkerson