Abstract: The present invention provides methods for determination of parameters in lithographic devices and applications by diffraction signature difference analysis, including determination of center of focus in lithography devices and applications.

Abstract: A threaded steel coupling with an exterior coating and interior case and threads, wherein the coupling body consists primarily of bainite and the interior case and threads consist primarily of a mixture of martensite and bainite. Also provided is a method of fabrication, including selective carburization of the interior threaded portion of the steel coupling forming the case and austempering.

Abstract: A combustor dome for use in a combustor has an igniter mounted in a central bore. Moving outward from the bore is a concentric pilot fuel passageway. Concentric about the pilot fuel passageway is an air passageway. Lastly, concentric about the air passageway is a premix passageway. The outlets of the pilot fuel passageway, the air passageway, and the premix passageway are generally coplanar.

Abstract: The present invention provides an anti-thrombogenic and cellular-adhesion coating composition for blood-contacting surfaces. The coating comprises a covalent complex of from 1 to 30 hydrophobic silyl moieties of Formula I: wherein R1 is an C1-18 alkyl or C6-32 aryl group, each R2 is independently selected from the group consisting of C1-18 alkyl and C6-32 aryl, R3 is N or O, n is a number from 1 to 10, directly bound to a heparin molecule via covalent bonding, with an adhesive molecule directly bound to the heparin molecule. In one embodiment, the coating comprises benzyl-(1,2 dimethyl)disilyl heparin, wherein an adhesive molecule, such as fibronectin, is bound to the heparin.

Abstract: A metallo-construct, which may be a peptide, is provided for use as a biological, therapeutic, diagnostic imaging, or radiotherapeutic agent, and for use in library or combinatorial chemistry methods. The construct has a conformationally constrained global secondary structure obtained upon complexing with a metal ion. The peptide constructs are of the general formula: R1—X—R2 where X is a plurality of amino acids and includes a complexing backbone for complexing metal ions, so that substantially all of the valences of the metal ion are satisfied upon complexation of the metal ion with X, resulting in a specific regional secondary structure forming a part of the global secondary structure; and where R1 and R2 each include from 0 to about 20 amino acids, the amino acids being selected so that upon complexing the metal ion with X at least a portion of either R1 or R2 or both have a structure forming the balance of the conformationally constrained global secondary structure.

Abstract: The present invention discloses an organic compound which assists in minimizing the appearance of or removing unwanted skin growths and discolorations without damaging or scarring the skin. The organic compound of the present invention include a mineral from the family of pyrophyllite and organic apple cider vinegar. The ratio of the bentonite to the vinegar is between about 1:1 to 1:1.5, by weight (grams) to by volume (milliliters). The mineral is preferably bentonite or montmorillonite. A method for making and applying the organic compound is also presently disclosed This method includes a first step of providing a mineral from the family of pyrophyllite. In a second step, organic apple cider vinegar is provided. The mineral is then mixed with the vinegar to form a paste. The paste is then applied to areas of the skin upon which there are growths. Preferably, between about 0.18 to about 0.21 grams of the paste should be applied to about every 0.5 cm of the growth.

Abstract: The invention relates to transgenic mammals characterized by 5-HT3 receptor over-expression in the central nervous system (CNS) . The mammals have particular utility as models for studying the role of 5-HT3 receptors in the CNS, especially for the study of reward pathways for alcohol and other substances of abuse.

Abstract: The invention provides segments of HSV-1 and HSV-2 glycoprotein B which include antigenic epitopes in the gB amino-proximal region that react with human antibodies in a type-specific manner, and epitopes in the gB carboxy-proximal region that cross-react with HSV-1 and HSV-2 antibodies.

Abstract: A metallo-construct, which may be a peptide, is provided for use as a biological, therapeutic, diagnostic imaging, or radiotherapeutic agent, and for use in library or combinatorial chemistry methods. The construct has a conformationally constrained global secondary structure obtained upon complexing with a metal ion. The peptide constructs are of the general formula:R.sub.1 --X--R.sub.2where X is a plurality of amino acids and includes a complexing backbone for complexing metal ions, so that substantially all of the valences of the metal ion are satisfied upon complexation of the metal ion with X, resulting in a specific regional secondary structure forming a part of the global secondary structure; and where R.sub.1 and R.sub.2 each include from 0 to about 20 amino acids, the amino acids being selected so that upon complexing the metal ion with X at least a portion of either R.sub.1 or R.sub.2 or both have a structure forming the balance of the conformationally constrained global secondary structure.