Patents Represented by Attorney Werten F. W. Bellamy
  • Patent number: 6107098
    Abstract: A uranium-containing/metal binding complex and process for the determinat of natural and depleted uranium in biological samples such as water, urine, blood serum, saliva, amniotic fluid, cerebrospinal fluid, sweat, stool extract, synovial fluid, tears, semen extract, sputum, and peritoneal fluid. The samples are mixed with a buffer, one or more masking agents, and a solubilizing compound, to form a uranium-containing metal binding complex composition, followed by the addition of a pyridylazo indicator dye to said composition. The increase in absorbance due to the uranium-dye complex is determined with a spectrophotometer or colorimeter.
    Type: Grant
    Filed: February 27, 1998
    Date of Patent: August 22, 2000
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventor: John F. Kalinich
  • Patent number: 5916224
    Abstract: A tendon repair clip implant system for placement on the dorsal side of a cerated or torn tendon to allow active range of motion post tendon repair, comprises: first and second clips. Each clip comprises:(i) two serrated sections joined by integral connecting section; the serrated sections being urgeable together to provide opposing mating teeth connection by arculate bending longitudinally around an axis of the connecting section;ii) the repair clip further comprising two relatively flat surfaces adjoining the connecting section and having openings therein through which sutures may be threaded and drawn through a lacerated tendon to assist in holding said tendon together; the openings being centered between a plurality of spikes extending from undersides of the flat surfaces to function as tendon inserts to assist in holding the lacerated tendon together.
    Type: Grant
    Filed: July 9, 1997
    Date of Patent: June 29, 1999
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventor: Vermon S. Esplin
  • Patent number: 5864855
    Abstract: A computer information processing system utilizes parallel processors for organizing and clustering a large number of documents into a large number of clusters for information analysis and retrieval. After the documents are translated into electronic digital documents, each document is converted into a vector based on weighted list of the occurence of different words and terms that appear in the document. The document vectors are grouped together into cluster vectors on different parallel processors according to similarities. New document vectors are simultaneously compared with existing cluster vectors in the different parallel processors.
    Type: Grant
    Filed: February 26, 1996
    Date of Patent: January 26, 1999
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Anthony S. Ruocco, Ophir Frieder
  • Patent number: 5762965
    Abstract: This invention relates to parenteral and mucosal vaccines against diseases aused by intracellular pathogens using antigens encapsulated within a biodegradable-biocompatible microspheres(matrix).
    Type: Grant
    Filed: February 9, 1996
    Date of Patent: June 9, 1998
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Paul R. Burnett, John E. Van Hamont, Robert H. Reid, Jean A. Setterstrom, Thomas C. Van Cott, Debrah L. Birx
  • Patent number: 5714515
    Abstract: A pharmaceutical composition comprising as an active phosphorylation poteal enhancing substance and an alpha-keto carboxylic acid or a pharmaceutically-acceptable salt thereof, its use and products containing the same.
    Type: Grant
    Filed: May 8, 1996
    Date of Patent: February 3, 1998
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventor: Rolf Bunger
  • Patent number: 5705197
    Abstract: A hybrid evaporation-extraction process for preparing microspheres of a p(DL-lactide-to-glycolide) biodegradable polymer, comprising:a. preparing a lyophilized biologically active material-sucrose matrix; adding acetonitrile solvent to biologically active material-sucrose matrix to form a solution;b. preparing a solution of a biodegradable poly (DL-lactide-co-glycolide) polymer by adding acetonitrile solvent to the polymer;c. adding the biodegradable poly (DL-lactide-co-glycolide) polymer acetonitrile solution to the biologically active material-sucrose acetonitrile solution;d. adding with stirring an oil containing lecithin to the poly (DL-lactide-co-glycolide) polymer-sucrose-biologically active material solution to evaporate acetonitrile and form an emulsion containing microspheres of poly (DL-lactide-co-glycolide) biodegradable polymers;e. adding the emulsion from step d. into a solvent selected from heptane, hexane, pentane or isopropanol; andf.
    Type: Grant
    Filed: August 16, 1996
    Date of Patent: January 6, 1998
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: John Van Hamont, Curt Thies, Robert H. Reid, Charles E. McQueen, Jean A. Setterstrom
  • Patent number: 5693343
    Abstract: In a solvent extraction process for preparing microspheres of a biodegrade polymer, the improvement comprising: preparing a homogenized antigen-sucrose matrix and adding a solvent to the sucrose-antigen matrix to form a solution; preparing a solution of a biodegradable polymer by adding a solvent to the polymer; adding the biodegradable polymer solution to the antigen-sucrose solution; adding an oil to the polymer-sucrose-antigen solution to form an emulsion having a controlled viscosity that corresponds to a predetermined average particle size of distributions of microspheres of biodegradable polymers; centrifuging the emulsion of controlled viscosity and removing the supernatant to obtain microspheres of a predetermined range of particle size distributions of from about 0.5 to about 7.0 micrometers.
    Type: Grant
    Filed: May 16, 1994
    Date of Patent: December 2, 1997
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Robert H. Reid, John E. van Hamont, William R. Brown, Egar C. Boedeker, Curt Thies
  • Patent number: 5585453
    Abstract: Polycyclic spiroorthoester which undergo expansion on polymerization to f resins, rather than shrinkage on polymerization, are employed in fabrication of composite, filament-reinforced, interceptor motor cases. The advantages which accrue to such use of the specified resins relate to the imparting of unique characteristics to the interceptor motor case such as increased structural strength, a reduction in the number of microcracks and voids, and improved bonding between resin and reinforcement. These unique characteristics impart benefits where needed since composite motor cases are fabricated from high strength filaments or tapes such as fiberglass, graphite, poly-p-phenyleneterephthalamide (Kevlar), in a polymeric matrix, and the primary mode of failure is due either to poor adhesion between the matrix and the filament or tapes or because of the development of microcracks or voids in the matrix.The spiroorthoester, 1,4,6-trioxaspiro [4.
    Type: Grant
    Filed: July 14, 1982
    Date of Patent: December 17, 1996
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventor: David C. Sayles
  • Patent number: 5536751
    Abstract: A pharmaceutical composition comprising as an active phophorylation potenl enhancing substance and an alpha-keto carboxylic acid or a pharmaceutically-acceptable salt thereof, its use and products containing the same.
    Type: Grant
    Filed: May 9, 1994
    Date of Patent: July 16, 1996
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventor: Rolf Bunger
  • Patent number: 5417986
    Abstract: This invention is directed to oral parenteral and intestinal vaccines and eir use against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres.
    Type: Grant
    Filed: April 10, 1992
    Date of Patent: May 23, 1995
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Robert H. Reid, Edgar C. Boedeker, John E. van Hamont, Jean A. Setterstrom
  • Patent number: 5399158
    Abstract: This invention relates to the prevention and treatment of thrombi using pminogen activators, including t-PA, urokinases, and streptokinases, in conjunction with intermittent (pulsed mode) ultrasound. A preferred modality interposes liquid-containing interface between the skin of the patient and the transducer of the ultrasound generator.
    Type: Grant
    Filed: January 27, 1993
    Date of Patent: March 21, 1995
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Carl G. Lauer, Barbara Alving
  • Patent number: 5375276
    Abstract: The present invention relates to a surgical table capable of supporting a litary litter. The table, comprising a base and at least one cross member, is made of lightweight, durable material, is portable, and is relatively easy to assemble, disassemble, and package for transport. The cross member may be positioned such that the patient's head or feet are elevated or lowered relative to the table's base. The fabric of the litter is used as the direct support for the patient while the patient receives medical attention.
    Type: Grant
    Filed: February 5, 1993
    Date of Patent: December 27, 1994
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: James H. Nelson, Leo W. Jenkins, Mark W. Brown
  • Patent number: 5350798
    Abstract: Tissue adhesive compositions are disclosed which comprise at least one 2-noacrylate ester of the general formula (I) ##STR1## in admixture with from about 2 percent to about 25 percent of at least one oxalic acid polymer of the general formula (II) ##STR2##
    Type: Grant
    Filed: August 17, 1993
    Date of Patent: September 27, 1994
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Charles L. Linden, Shalaby W. Shalaby
  • Patent number: 5331010
    Abstract: The compounds belong to the class of non-narcotic, non-opiate derivatives the 1-phenylalkanecarboxylic acid basic structure useful as anticonvulsant and neuroprotective agents. The compounds include novel derivatives as well as previously published species. Methods for controlling convulsions in a variety of pharmaceutical formulations and modalities are also provided.
    Type: Grant
    Filed: June 5, 1991
    Date of Patent: July 19, 1994
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Amy H. Newman, Silvia N. Calderon, Frank C. Tortella
  • Patent number: 5320069
    Abstract: An improved small animal restraint device is provided which enables an inidual to conduct ocular examinations of a small animal. The device minimizes manipulation of the eyes of the animal and eliminates recovery time associated with anesthetics, while also reducing examination time. The restraint device comprises a cylinder having a longitudinal slot in the wall thereof. A conical member which is attached to one end of the cylinder includes a pair of eye openings in the upper wall thereof and a nose opening at the apex thereof. A plunger placed in the cylinder at the other end thereof assists in holding the animal in place. A set screw, which extends through the slot in the wall of the cylinder, secures the plunger in place.
    Type: Grant
    Filed: April 28, 1992
    Date of Patent: June 14, 1994
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: George W. Anderson, Jr., Wade B. Lawrence, Jae-Ouk Lee, Michael J. Young
  • Patent number: 5308114
    Abstract: A wire cutter for electrically cutting a path through wires to allow a land ehicle to pass therethrough is provided. The wire cutter does not use the forward motion of the vehicle to provide the actual cutting and in general can cut any thickness of wire located in front of the vehicle. The wire cutter device includes first and second conductive rods mounted in spaced relationship and connected to voltages of different values, e.g., to the positive and negative terminals of a power supply. A wire catcher device, comprising a pair of arms which are arranged in a U-shaped configuration and on which the rods are mounted, is provided for capturing wires located in the path of the vehicle and for guiding wires so captured to the rods so as to complete an electrical circuit through the rods and thus provide melting of wires so captured.
    Type: Grant
    Filed: December 8, 1992
    Date of Patent: May 3, 1994
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Robert C. Williams, Stephen W. Bachinski
  • Patent number: 5298423
    Abstract: Nucleotide sequences coding for Hantaan virus nucleocapsid protein and glproteins G1 and G2 can be used to produce these proteins for vaccine and diagnostic applications.
    Type: Grant
    Filed: November 14, 1991
    Date of Patent: March 29, 1994
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Joel M. Dalrymple, Connie S. Schmaljohn
  • Patent number: 5290553
    Abstract: A method of preparing substantially purified alkaloids from seeds, stems, uit-rind and bark of a plant selected from Picralima nitida, Gongronema latifolia, Dorstenia multiradiata, Cola attiensis, Rothmania withfieldii and Desmodium gangeticum, for use in the treatment of protozoal diseases, comprising:pulverizing said plant;a first solvent, drying the extracted material and re-extracting the dried material with a different solvent;extracting a fresh sample of said plant with boiling water;filtering and concentrating the boiling water solvent extracts under reduced pressure;concentrating the dried extract to a gum and re-extracting said gum with an aqueous acidic HCl solution;filtering the acidic extract and making it alkaline to a pH of about 9 with a concentration NaOH solution;extracting the alkaline solution with dichloromethane;concentrating organic layers of the extracted alkaline solution to dryness under reduced pressure to obtain an alkaloid fraction; andseparating the alkaloid fraction by liquid chr
    Type: Grant
    Filed: July 22, 1991
    Date of Patent: March 1, 1994
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Maurice M. Iwu, Daniel L. Klayman, Joan E. Jackson, John D. Tally, Steven L. Andersen
  • Patent number: 5281597
    Abstract: This invention is directed to heterocyclic and aromatic thiosemicarbazones seful in the treatment of filariasis and in an animal, including humans.
    Type: Grant
    Filed: November 8, 1991
    Date of Patent: January 25, 1994
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: John W. McCall, Daniel L. Klayman, Ai Jeng Lin, Kenneth E. Kinnamon, Max Grogl
  • Patent number: 5264290
    Abstract: A highly improved elastomeric composition, process, and articles made thef, wherein the novel composition is characterized by greatly increased wear longevity, thermomechanical stability, highly improved tear and tensile strength at high temperature usage, in addition to high resistance to burning in open flame, as well as high resistance to cutting, chipping, cracking and crack propagation particularly in product use for tank track pads and other related track system elastomeric component products; wherein the improved composition is a unique combination of its respective polymer, filler, curing and antidegradant system, in which the polymer system either consists of about 100 parts by weight of highly saturated nitrile polymer or of various novel blends of the highly saturated usually in majority amounts together with minority amounts of carboxylated nitrile, with or without additional minority or near equal parts of nitrile rubber; and wherein the curing system may include various blends of from between ab
    Type: Grant
    Filed: March 4, 1992
    Date of Patent: November 23, 1993
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Paul Touchet, Gumersindo Rodriguez, Paul E. Gatza, D. Patrick Butler, Dawn M. Crawford, Alan R. Teets, Henry O. Feuer, David P. Flanagan