Patents Assigned to Advanced Cardiovascular Systems, Inc.
  • COATINGS FOR DRUG DELIVERY DEVICES
    Publication number: 20130150460
    Abstract: A polymer coating for medical devices based on a polyolefin derivative. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include homo-, co-, and terpolymers having at least one olefin-derived unit and at least one unit derived from vinyl alcohol, allyl alcohol and derivatives thereof.
    Type: Application
    Filed: January 4, 2013
    Publication date: June 13, 2013
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventor: Advanced Cardiovascular Systems, Inc.
  • COATINGS FOR DRUG DELIVERY DEVICES
    Publication number: 20130150459
    Abstract: A polymer coating for medical devices based on a polyolefin derivative. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include homo-, co-, and terpolymers having at least one olefin-derived unit and at least one unit derived from vinyl alcohol, allyl alcohol and derivatives thereof.
    Type: Application
    Filed: January 4, 2013
    Publication date: June 13, 2013
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventor: Advanced Cardiovascular Systems, Inc.
  • Methods of Forming Coatings with a Crystalline or Partially Crystalline Drug for Implantable Medical Devices
    Publication number: 20130149431
    Abstract: Methods for making coatings on an implantable device such as a drug-eluting stent comprising a polymer and nano or microparticles of a drug in slow-dissolving polymorph, implantable devices produced by the methods and methods of using the coatings are provided.
    Type: Application
    Filed: December 20, 2012
    Publication date: June 13, 2013
    Applicant: ADVANCED CARDIOVASCULAR SYSTEMS, INC.
    Inventor: Advanced Cardiovascular Systems, Inc.
  • Methods of Forming Coatings with a Crystalline or Partially Crystalline Drug for Implantable Medical Devices using Sonocrystallization
    Publication number: 20130142939
    Abstract: Methods for making coatings on an implantable device such as a drug-eluting stent comprising a polymer and nano or microparticles of a drug in slow-dissolving polymorph, implantable devices produced by the methods and methods of using the coatings are provided.
    Type: Application
    Filed: December 18, 2012
    Publication date: June 6, 2013
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventor: Advanced Cardiovascular Systems, Inc.
  • Transition matching stent
    Patent number: 8454676
    Abstract: The bending flexibility profile of a stent closely matches the flexibilities of the stent delivery system on either side of the stent. In one embodiment, a stent has a longitudinal axis and at least one link attaching each ring to an adjacent ring. The links closest to the stent end rings have the greatest bending flexibility and the links closest to the center of the stent have the least bending flexibility.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: June 4, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Karim Said Osman
  • COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLY(HYDROXY-ALKANOATES) AND DIACID LINKAGES
    Publication number: 20130123422
    Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings include block-polymers comprising at least one poly(hydroxyacid) or poly(hydroxy-alkanoate) block, at least one block of a biologically compatible polymer and at least one type of linking moiety.
    Type: Application
    Filed: November 27, 2012
    Publication date: May 16, 2013
    Applicant: ADVANCED CARDIOVASCULAR SYSTEMS, INC.
    Inventor: Advanced Cardiovascular Systems, Inc.
  • Intravascular stent and method of use
    Patent number: 8439966
    Abstract: An expandable stent is implanted in a body lumen, such as a coronary artery, peripheral artery, or other body lumen for treating an area of vulnerable plaque. The invention provides for a an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. A central section is positioned between distal and proximal sections and is aligned with the area of vulnerable plaque to enhance growth of endothelial cells over the fibrous cap of the vulnerable plaque to reinforce the area and reduce the likelihood of rupture.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: May 14, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Timothy Limon
  • INTRAVASCULAR STENT AND METHOD OF USE
    Publication number: 20130116769
    Abstract: An expandable stent is implanted in a body lumen, such as a coronary artery, peripheral artery, or other body lumen for treating an area of vulnerable plaque. The invention provides for a an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. A central section is positioned between distal and proximal sections and is aligned with the area of vulnerable plaque to enhance growth of endothelial cells over the fibrous cap of the vulnerable plaque to reinforce the area and reduce the likelihood of rupture.
    Type: Application
    Filed: December 27, 2012
    Publication date: May 9, 2013
    Applicant: ADVANCED CARDIOVASCULAR SYSTEMS, INC.
    Inventor: ADVANCED CARDIOVASCULAR SYSTEMS, INC.
  • COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLY(HYDROXY-ALKANOATES) AND DIACID LINKAGES
    Publication number: 20130116380
    Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings including block-polymers comprising at least one poly(hydroxyacid) or poly(hydroxy-alkanoate) block, at least one block of a biologically compatible polymer and at least one type of linking moiety.
    Type: Application
    Filed: November 27, 2012
    Publication date: May 9, 2013
    Applicant: ADVANCED CARDIOVASCULAR SYSTEMS, INC.
    Inventor: ADVANCED CARDIOVASCULAR SYSTEMS, INC.
  • Delivery system for a device such as a stent
    Patent number: 8435279
    Abstract: A delivery system for a medical device. The delivery system comprises an inner member, a retractable sheath disposed over the inner member and being slideable over the inner member, and a retraction member coupled to the retractable sheath and disposed at least in portion within the retractable sheath, the retraction member being slideable over the inner member. An axial movement of the retraction member retracts or actuates the retractable member.
    Type: Grant
    Filed: June 14, 2005
    Date of Patent: May 7, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Dagmar Beyerlein, Christopher Feezor, Karim Osman, Denise Horrilleno Burns, Carla Rosa Pienknagura, Barbara Stamberg
  • Stent support devices
    Patent number: 8430057
    Abstract: A collet shaped to minimize the contact area of a stent end with a surface of the collet. The collet has an end surface for contacting a stent end that includes a raised or projecting portion and a flat or relatively flat portion. The projecting, portion has at least three segments radiating from a center to the edge of the surface.
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: April 30, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Ryan E. Guerriero, Yung-Ming Chen, Celenia Gutierrez, Ian J. Coulson, Nathan Harold, Andrew Tochterman
  • METHODS FOR LASER CUTTING AND PROCESSING TUBING TO MAKE MEDICAL DEVICES
    Publication number: 20130098131
    Abstract: A method for making a device includes providing a tubular member which will be formed into the device, masking at least a portion of the inner surface of the tubular member with a removable sacrificial material, selectively removing a portion of the tubular member and sacrificial material using a laser device, and mechanically removing the sacrificial material from the inner surface of the tubular member. Ultrasonic energy could be applied to a workpiece which is being laser cut to prevent any generated slag from welding itself to an exposed surface of the workpiece. A compressed fluid or gas, such as air, could be used to clean the surface of the laser-cut workpiece to remove slag formation which adheres to the surface of the cut workpiece.
    Type: Application
    Filed: December 7, 2012
    Publication date: April 25, 2013
    Applicant: ADVANCED CARDIOVASCULAR SYSTEMS, INC.
    Inventor: ADVANCED CARDIOVASCULAR SYSTEMS, INC
  • Biobeneficial coating compositions and methods of making and using thereof
    Patent number: 8426476
    Abstract: A biobeneficial coating composition for coating an implantable device, such as a drug eluting stent, a method of coating the device with the composition, and an implantable device coated with the composition are provided.
    Type: Grant
    Filed: September 2, 2010
    Date of Patent: April 23, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Stephen D. Pacetti
  • Biodegradable stent of a polyorthoester polymer or a polyanhydride polymer
    Patent number: 8414642
    Abstract: A stent is fabricated utilizing a polymer that is selected for its tendency to degrade from the surface inwardly rather than undergo bulk erosion so as to substantially reduce the risk of large particles becoming detached and being swept downstream. Such polymer is hydrophobic yet has water-labile linkages interconnecting the monomers. Ester or imide bonds are incorporated in the polymer to render the surface degrading materials suitable for use in stent applications. The stent may be coated with such polymer or may be wholly formed therefrom.
    Type: Grant
    Filed: December 1, 2008
    Date of Patent: April 9, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Debashis Dutta
  • Drug delivery after biodegradation of the stent scaffolding
    Patent number: 8398706
    Abstract: Disclosed herein is a stent comprising: a bioabsorbable polymeric scaffolding; and a coating comprising a bioabsorbable material on at least a portion of the scaffolding, wherein the degradation rate of all or substantially all of the bioabsorbable polymer of the scaffolding is faster than the degradation rate of all or substantially all of the bioabsorbable material of the coating.
    Type: Grant
    Filed: April 13, 2011
    Date of Patent: March 19, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: David C. Gale, Bin Huang
  • Method and Apparatus for Coating a Stent
    Publication number: 20130064966
    Abstract: A method of coating a stent comprises contacting a first axial portion of a stent with a support element, such that a second axial portion does not contact the support element or any other support element, applying a coating material to the second axial portion, and inhibiting or preventing application of the coating material on the first axial portion. A shuttle sheath can be used to push the stent off the support element.
    Type: Application
    Filed: November 5, 2012
    Publication date: March 14, 2013
    Applicant: Advanced Cardiovascular System, Inc.
    Inventor: Advanced Cardiovascular System, Inc.
  • Abluminal stent coating apparatus and method using a brush assembly
    Patent number: 8394447
    Abstract: The apparatus and method use an optical feedback system to align a brush assembly with a stent strut. Once alignment is achieved, a coating is dispensed onto the stent strut via the brush assembly and the brush assembly is moved along the stent strut to coat the stent strut.
    Type: Grant
    Filed: July 27, 2009
    Date of Patent: March 12, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Grayson Morris, Svava Maria Atladottir, Carla Pienknagura
  • Stents with profiles for gripping a balloon catheter and molds for fabricating stents
    Patent number: 8393887
    Abstract: Embodiments of stents having profiles that improve gripping of the stent on a stent delivery system are provided. Additionally, embodiments of molds for fabricating the stents are provided. A radially expandable stent can comprise a proximal section tapering inward to a proximal end of the stent and a distal section tapering inward to a distal end of the stent. The tapered sections can be adapted to improve the attachment of the stent to the delivery system and to facilitate the delivery of the mounted device into and through a bodily lumen.
    Type: Grant
    Filed: May 3, 2010
    Date of Patent: March 12, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Daniel Gene Brown, Hector Onello Torres, Mark Harris, Chris Andrews
  • Coating abluminal surfaces of stents and other implantable medical devices
    Patent number: 8387553
    Abstract: A sleeve is positioned over a radially-expandable rod assembly and a stent is positioned over the sleeve. A mandrel is inserted into the rod assembly to thereby press the sleeve against the inner surface of the stent and expand the stent. A coating (such as a solvent, a polymer and/or a therapeutic substance) is then applied to the outer (abluminal) surfaces of the stent, by spraying, for example. The sleeve advantageously prevents the coating material from being applied to inner (luminal) surfaces of the stent and also allows the coating material to be efficiently applied to the abluminal surfaces.
    Type: Grant
    Filed: July 8, 2010
    Date of Patent: March 5, 2013
    Assignee: Advanced Cardiovascular Systems Inc.
    Inventors: Yung Ming Chen, Jeff H. Smith, Celenia Gutierrez
  • Low profile stent with flexible link
    Patent number: 8388675
    Abstract: The invention provides an improved stent design for repairing vasculature, the stent having rings including struts defining first peaks and second peaks, selected second peaks of adjacent rings being connected by links. The stent design incorporates non-linear links with undulating portions extending generally perpendicular to or circumferentially with respect to a longitudinal axis of the stent and adjacent first peaks with different longitudinal lengths such that stent flexibility is increased without sacrificing stent compression for delivery.
    Type: Grant
    Filed: March 9, 2009
    Date of Patent: March 5, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Ainsworth, Andreina P. Gomez