Abstract: A stent mounting device and a method of coating a stent using the device are provided. The mandrel is made from or is coated with a hydrophobic or hydrophilic material, depending on the type of coating composition that is employed.
Type:
Grant
Filed:
March 18, 2004
Date of Patent:
January 8, 2013
Assignee:
Advanced Cardiovascular Systems, Inc.
Inventors:
Philip S. Yip, Fuh-Wei Tang, Anthony Andreacchi
Abstract: A polymer coating for medical devices based on a polyolefin derivative. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include homo-, co-, and terpolymers having at least one olefin-derived unit and at least one unit derived from vinyl alcohol, allyl alcohol and derivatives thereof.
Abstract: An expandable stent is implanted in a body lumen, such as a coronary artery, peripheral artery, or other body lumen for treating an area of vulnerable plaque. The invention provides for a an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. A central section is positioned between distal and proximal sections and is aligned with the area of vulnerable plaque to enhance growth of endothelial cells over the fibrous cap of the vulnerable plaque to reinforce the area and reduce the likelihood of rupture.
Abstract: A drug-eluting stent delivery system has a balloon disposed about at least a portion of a catheter, the balloon having a first end and a second end and a working length therebetween, the first end and the second end each including a tapered portion, each tapered portion being attached to the catheter, the balloon being inflatable from a collapsed configuration to an inflated configuration. A drug-eluting stent has a first end and a second end, the first end and the second end each including a tapered portion, wherein the drug-eluting stent is disposed over the balloon such that at least a portion of the first end and the second end of the balloon are covered by the tapered drug-eluting stent.
Abstract: The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. The stent can be compressed or crimped onto a catheter to a very low profile since the peaks that are adjacent the curved portion of the undulating link are shorter than other peaks in the same cylindrical ring to prevent overlap yet still achieve a very low profile, tightly crimped stent onto a catheter.
Abstract: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
Type:
Grant
Filed:
March 12, 2010
Date of Patent:
December 25, 2012
Assignee:
Advanced Cardiovascular Systems, Inc.
Inventors:
Syed F. A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evgenia Mandrusov
Abstract: An improved stent design and stent delivery catheter assembly for repairing a main vessel proximal to a side branch vessel and the opening to the side branch vessel forming a bifurcation. The stent is particularly useful in treating a bifurcation where plaque is present proximal to the side branch vessel but not distal to the side branch vessel. The present invention includes a trap door stent design, a stent delivery catheter assembly, and the method for delivering and implanting the stent in a bifurcated vessel. More particularly, the invention relates to a stent having rings aligned along a common longitudinal axis and connected by links. The stent has first rings that are implanted in the main vessel proximal to the bifurcation and one or more second rings forming a trap door section to appose the opening to the side branch vessel and the main vessel.
Abstract: A method of crimping a stent on a balloon of a catheter assembly is provided. A polymeric stent is disposed over a balloon in an inflated configuration. The stent is crimped over the inflated balloon to a reduced crimped configuration so that the stent is secured onto the balloon. The balloon wall membrane is wedged or pinched between the strut elements of the stent for increasing the retention of the stent on the balloon.
Type:
Grant
Filed:
June 19, 2006
Date of Patent:
December 18, 2012
Assignee:
Advanced Cardiovascular Systems, Inc.
Inventors:
Bin Huang, David C. Gale, Daniel Castro
Abstract: A method for making a device includes providing a tubular member which will be formed into the device, masking at least a portion of the inner surface of the tubular member with a removable sacrificial material, selectively removing a portion of the tubular member and sacrificial material using a laser device, and mechanically removing the sacrificial material from the inner surface of the tubular member. Ultrasonic energy could be applied to a workpiece which is being laser cut to prevent any generated slag from welding itself to an exposed surface of the workpiece. A compressed fluid or gas, such as air, could be used to clean the surface of the laser-cut workpiece to remove slag formation which adheres to the surface of the cut workpiece.
Type:
Grant
Filed:
December 31, 2008
Date of Patent:
December 18, 2012
Assignee:
Advanced Cardiovascular Systems, Inc.
Inventors:
Michael R. Bialas, Robert P. Barbier, David Strauss, David Mackiewicz, Pius Kienzle, Mihaela Baldi
Abstract: A stent is coated by ejecting droplets of a coating substance from a reservoir containing a coating substance. A reservoir housing can have a plurality of reservoir compartments. A transducer is used to eject the coating substance from the reservoir. Energy from the transducer is focused at a meniscus or an interface between the coating substance and another coating substance in the reservoir.
Type:
Grant
Filed:
June 17, 2011
Date of Patent:
November 27, 2012
Assignee:
Advanced Cardiovascular Systems, Inc.
Inventors:
Jason Van Sciver, Yung-Ming Chen, Lothar Kleiner
Abstract: An apparatus for coating a stent comprises a coating solution reservoir, a stent support for carrying a stent adjacent the reservoir, transducers for generating waves through the coating solution, and a controller that controls timing at which the transducers are powered in order to eject a droplet of the coating solution.
Abstract: A support assembly for a stent and a method of using the same to coat a stent are provided. The support assembly provides for minimum contact between the stent and the support assembly so as to reduce or eliminate coating defects.
Type:
Grant
Filed:
July 28, 2008
Date of Patent:
November 20, 2012
Assignee:
Advanced Cardiovascular Systems, Inc.
Inventors:
Domingo S. Madriaga, Anh Tran, Arthur J. Wen
Abstract: A sleeve is positioned over a radially-expandable rod assembly and a stent is positioned over the sleeve. A mandrel is inserted into the rod assembly to thereby press the sleeve against the inner surface of the stent and expand the stent. A coating (such as a solvent, a polymer and/or a therapeutic substance) is then applied to the outer (abluminal) surfaces of the stent, by spraying, for example. The sleeve advantageously prevents the coating material from being applied to inner (luminal) surfaces of the stent and also allows the coating material to be efficiently applied to the abluminal surfaces.
Type:
Grant
Filed:
July 8, 2010
Date of Patent:
November 20, 2012
Assignee:
Advanced Cardiovascular Systems Inc.
Inventors:
Yung Ming Chen, Jeff H. Smith, Celenia Gutierrez
Abstract: A catheter which has an elongated shaft having a layer of an ultra high molecular weight polyolefin, such as a melt-extruded ultra high molecular weight polyethylene (UHMWPE). The UHMWPE, forming at least in part a surface of the shaft, facilitates sliding a blood/contrast coated device along the shaft surface, and preferably substantially prevents or inhibits agglomerations of blood and contrast from adhering to the surface of the shaft in a patient's body lumen. In a presently preferred embodiment, the layer has a lubricious coating, such that the coated surface of the UHMWPE layer significantly decreases the force produced by the blood/contrast coated device sliding along the coated surface.
Type:
Grant
Filed:
March 6, 2006
Date of Patent:
November 13, 2012
Assignee:
Advanced Cardiovascular Systems, Inc.
Inventors:
Jeong S. Lee, Kenneth L. Wantink, Roseminda White