Patents Assigned to Advanced Cardiovascular Systems, Inc.
  • Patent number: 8349388
    Abstract: A stent mounting device and a method of coating a stent using the device are provided. The mandrel is made from or is coated with a hydrophobic or hydrophilic material, depending on the type of coating composition that is employed.
    Type: Grant
    Filed: March 18, 2004
    Date of Patent: January 8, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Philip S. Yip, Fuh-Wei Tang, Anthony Andreacchi
  • Patent number: 8349389
    Abstract: A stent fixture for supporting a stent during the application of a coating substance is provided.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: January 8, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Nathan Harold, Antonio Garcia, Andrew Tochterman
  • Patent number: 8349350
    Abstract: A polymer coating for medical devices based on a polyolefin derivative. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include homo-, co-, and terpolymers having at least one olefin-derived unit and at least one unit derived from vinyl alcohol, allyl alcohol and derivatives thereof.
    Type: Grant
    Filed: July 29, 2009
    Date of Patent: January 8, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Stephen Dirk Pacetti
  • Patent number: 8343568
    Abstract: A stent fixture for supporting a stent during formation of a coating is provided.
    Type: Grant
    Filed: September 24, 2010
    Date of Patent: January 1, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Yung-Ming Chen, Allan Bradshaw, Philip C. Foreman, Greg Teaby
  • Patent number: 8343209
    Abstract: An expandable stent is implanted in a body lumen, such as a coronary artery, peripheral artery, or other body lumen for treating an area of vulnerable plaque. The invention provides for a an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. A central section is positioned between distal and proximal sections and is aligned with the area of vulnerable plaque to enhance growth of endothelial cells over the fibrous cap of the vulnerable plaque to reinforce the area and reduce the likelihood of rupture.
    Type: Grant
    Filed: June 26, 2012
    Date of Patent: January 1, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Timothy Limon
  • Patent number: 8343206
    Abstract: A drug-eluting stent delivery system has a balloon disposed about at least a portion of a catheter, the balloon having a first end and a second end and a working length therebetween, the first end and the second end each including a tapered portion, each tapered portion being attached to the catheter, the balloon being inflatable from a collapsed configuration to an inflated configuration. A drug-eluting stent has a first end and a second end, the first end and the second end each including a tapered portion, wherein the drug-eluting stent is disposed over the balloon such that at least a portion of the first end and the second end of the balloon are covered by the tapered drug-eluting stent.
    Type: Grant
    Filed: October 31, 2011
    Date of Patent: January 1, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Stephen Dirk Pacetti
  • Publication number: 20120330403
    Abstract: The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. The stent can be compressed or crimped onto a catheter to a very low profile since the peaks that are adjacent the curved portion of the undulating link are shorter than other peaks in the same cylindrical ring to prevent overlap yet still achieve a very low profile, tightly crimped stent onto a catheter.
    Type: Application
    Filed: August 31, 2012
    Publication date: December 27, 2012
    Applicant: ADVANCED CARDIOVASCULAR SYSTEMS, INC.
    Inventors: Andreina P. Gomez, Diem Uyen Ta
  • Patent number: 8337874
    Abstract: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: December 25, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evgenia Mandrusov
  • Patent number: 8337540
    Abstract: An improved stent design and stent delivery catheter assembly for repairing a main vessel proximal to a side branch vessel and the opening to the side branch vessel forming a bifurcation. The stent is particularly useful in treating a bifurcation where plaque is present proximal to the side branch vessel but not distal to the side branch vessel. The present invention includes a trap door stent design, a stent delivery catheter assembly, and the method for delivering and implanting the stent in a bifurcated vessel. More particularly, the invention relates to a stent having rings aligned along a common longitudinal axis and connected by links. The stent has first rings that are implanted in the main vessel proximal to the bifurcation and one or more second rings forming a trap door section to appose the opening to the side branch vessel and the main vessel.
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: December 25, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Joseph R. Callol, W. Stan Wilson
  • Patent number: 8333000
    Abstract: A method of crimping a stent on a balloon of a catheter assembly is provided. A polymeric stent is disposed over a balloon in an inflated configuration. The stent is crimped over the inflated balloon to a reduced crimped configuration so that the stent is secured onto the balloon. The balloon wall membrane is wedged or pinched between the strut elements of the stent for increasing the retention of the stent on the balloon.
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: December 18, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, David C. Gale, Daniel Castro
  • Patent number: 8333897
    Abstract: A method for making a device includes providing a tubular member which will be formed into the device, masking at least a portion of the inner surface of the tubular member with a removable sacrificial material, selectively removing a portion of the tubular member and sacrificial material using a laser device, and mechanically removing the sacrificial material from the inner surface of the tubular member. Ultrasonic energy could be applied to a workpiece which is being laser cut to prevent any generated slag from welding itself to an exposed surface of the workpiece. A compressed fluid or gas, such as air, could be used to clean the surface of the laser-cut workpiece to remove slag formation which adheres to the surface of the cut workpiece.
    Type: Grant
    Filed: December 31, 2008
    Date of Patent: December 18, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Michael R. Bialas, Robert P. Barbier, David Strauss, David Mackiewicz, Pius Kienzle, Mihaela Baldi
  • Patent number: 8329158
    Abstract: Embodiments of the present invention provides medical devices comprising poly(hydroxyalkanoates) and agents.
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: December 11, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Stephen D. Pacetti
  • Patent number: 8329157
    Abstract: Compositions comprising poly(hydroxyalkanoates) and agents for use with medical articles are described.
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: December 11, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Stephen D. Pacetti
  • Patent number: 8323329
    Abstract: Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed.
    Type: Grant
    Filed: May 3, 2010
    Date of Patent: December 4, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: David C. Gale, Bin Huang, Timothy Limon, Vincent J. Gueriguian
  • Patent number: 8318236
    Abstract: A stent is coated by ejecting droplets of a coating substance from a reservoir containing a coating substance. A reservoir housing can have a plurality of reservoir compartments. A transducer is used to eject the coating substance from the reservoir. Energy from the transducer is focused at a meniscus or an interface between the coating substance and another coating substance in the reservoir.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: November 27, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jason Van Sciver, Yung-Ming Chen, Lothar Kleiner
  • Publication number: 20120291703
    Abstract: An apparatus for coating a stent comprises a coating solution reservoir, a stent support for carrying a stent adjacent the reservoir, transducers for generating waves through the coating solution, and a controller that controls timing at which the transducers are powered in order to eject a droplet of the coating solution.
    Type: Application
    Filed: August 6, 2012
    Publication date: November 22, 2012
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventor: Yung Ming Chen
  • Patent number: 8312837
    Abstract: A support assembly for a stent and a method of using the same to coat a stent are provided. The support assembly provides for minimum contact between the stent and the support assembly so as to reduce or eliminate coating defects.
    Type: Grant
    Filed: July 28, 2008
    Date of Patent: November 20, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Domingo S. Madriaga, Anh Tran, Arthur J. Wen
  • Patent number: 8312838
    Abstract: A sleeve is positioned over a radially-expandable rod assembly and a stent is positioned over the sleeve. A mandrel is inserted into the rod assembly to thereby press the sleeve against the inner surface of the stent and expand the stent. A coating (such as a solvent, a polymer and/or a therapeutic substance) is then applied to the outer (abluminal) surfaces of the stent, by spraying, for example. The sleeve advantageously prevents the coating material from being applied to inner (luminal) surfaces of the stent and also allows the coating material to be efficiently applied to the abluminal surfaces.
    Type: Grant
    Filed: July 8, 2010
    Date of Patent: November 20, 2012
    Assignee: Advanced Cardiovascular Systems Inc.
    Inventors: Yung Ming Chen, Jeff H. Smith, Celenia Gutierrez
  • Patent number: 8309114
    Abstract: Methods and devices relating to polymer-bioceramic composite implantable medical devices are disclosed.
    Type: Grant
    Filed: May 5, 2011
    Date of Patent: November 13, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: David C. Gale, Yunbing Wang, Syed Faiyaz Ahmed Hossainy, Bin Huang, Garth L. Wilkes, Vincent J. Gueriguian
  • Patent number: 8308711
    Abstract: A catheter which has an elongated shaft having a layer of an ultra high molecular weight polyolefin, such as a melt-extruded ultra high molecular weight polyethylene (UHMWPE). The UHMWPE, forming at least in part a surface of the shaft, facilitates sliding a blood/contrast coated device along the shaft surface, and preferably substantially prevents or inhibits agglomerations of blood and contrast from adhering to the surface of the shaft in a patient's body lumen. In a presently preferred embodiment, the layer has a lubricious coating, such that the coated surface of the UHMWPE layer significantly decreases the force produced by the blood/contrast coated device sliding along the coated surface.
    Type: Grant
    Filed: March 6, 2006
    Date of Patent: November 13, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jeong S. Lee, Kenneth L. Wantink, Roseminda White