Abstract: At least one substrate part for is provided for coating. A first deposition is provided on the at least one support part as microstructuring of at least one first substance selected from the group consisting of rhenium, ruthenium, rhodium, palladium, silver, osmium, iridium, platinum, gold, tin, zinc, copper, cobalt, lead, nickel and alloys comprising these, from at least one first compound which provides the at least one first substance. A second deposition is provided on the at least one support part as a nano-structuring of at least one second substance chosen from a group comprising rhenium, ruthenium, rhodium, palladium, silver, osmium, iridium, platinum, gold and/or alloys thereof, of at least one second compound which provides the at least one second substance, in a solution.

Abstract: Improvements in MR spiral imaging are provided in that spiral segments (2 to 8) are reordered, in particular alternately traversed and/or permuted. Moreover, repeatedly approaching the same post-trajectory points (16) between the acquisitions of the spiral segments (2 to 8) is provided, in which the post-trajectory points (16) are located outside of the center (18) of k-space (9), preferably outside of a region (20) of the k-space (9) covered by the spiral segments (2 to 8).

Abstract: The present invention discloses an extracellular matrix comprising a modified polysaccharide consisting of repeating disaccharide units whereby in at least 11% of the disaccharide units one primary alcohol group is oxidized into a carboxylic acid.

Abstract: An electrochemical method and an electrochemical sensor for breath analysis of single or multiple analytes using a porous, preferably flexible and disposable supporting material is provided, a salt is incorporated, and which can be wetted in contact with the exhaled breath condensate. The electrochemical method acting simultaneously as sampling method, as an electrolyte and as a support for the electrode structures. In some embodiments the salt may be hygroscopic, such that the porous substrate stays wet. To ensure that the obtained signal originates from the analyte, the electrochemical sensor preferably exhibits a differential electrode design, including a sensing (analyte-sensitive) and a blank (analyte-insensitive) electrode in order to isolate and remove the background signals.

Abstract: A magnetic field probe (1) having a capsule (3), in which an MR-active substance (5) is encapsulated. Two coils (7, 9) are preferably arranged in the capsule (3). Advantageous production methods for magnetic field probes (1) are also described, as well as advantageous uses of the magnetic field probe (1) and methods in which magnetic field probes (1) of this kind and arrangements of magnetic field probes (1) are used.

Abstract: An implantable fluid pump system is disclosed for supporting or initiating flow inside a hollow organ through which fluid circulates, in particular the heart. The fluid pump system comprises an intracardiac module, which includes two separate fluid channels, each of which possesses an intracardiac fluid channel opening and, located opposite the latter, an extracardiac fluid channel opening, a fastening module, which provides a joining contour for purposes of joining onto the intracardiac module in a fluid-tight manner, and a fastening structure for purposes of intracorporeal fastening onto the hollow organ, and a pump module, which can be mounted in a releasable manner directly or indirectly onto the intracardiac module, and can be attached in a fluid-tight manner to the extracardiac fluid channel openings in order to produce a fluid-tight connection of both fluid channels.

Abstract: An electrophoretic separation device includes an anode and a cathode, a porous scaffold material, and a liquid separation medium, wherein the separation medium is located inside the porous scaffold material, is in contact with the cathode and the anode, and has been applied to the porous scaffold material in form of a custom-made geometrical shape defining a migration path for a biomolecule-containing sample, wherein the sample is enclosed by the separation medium.

Abstract: A flexible implantable electrode arrangement includes an electrically insulating carrier structure of a first polymer material, an electrically conductive layer, and an electrically insulating cover layer of a second polymer material. The electrically conductive layer includes an electrically conductive carbon fiber layer. The electrically conductive layer integrally forms an implantable electrode, a conductor track connected to the implantable electrode, and a contact pad. The electrically insulating cover layer at least partially covers the electrically conductive layer.

Abstract: The formation of compensation elements (7) on an at least partially transparent membrane (2) that provides the actuator elements (5) to compensate or neutralize unwanted deformations of the compartment (3), e.g. induced by gravity effects, and/or to generate positive (convex) deflections of a limiting membrane (14), where the plurality of actuator elements (5) and the at least one compensation element (7) are provided at a common electrode membrane (2).

Abstract: A piezoelectric actuator includes a deflectable membrane and a piezoelectric element attached to a part of the deflectable membrane for exerting a mechanical force on the deflectable membrane. The piezoelectric element is operable to perform an expansion and a contraction motion depending on an electric field applied to the piezoelectric element. The piezoelectric element leaves open a central region of the deflectable membrane and has a peripheral outline that does not coincide with an outline of the deflectable membrane.

Abstract: A method is used to carry out a magnetic resonance measurement with at least one echo train with n spin echoes and prospective movement correction. Movement correction data for each echo train is updated at the start of the echo train and is then updated again at most partially for the spin echoes.

Abstract: The present invention relates to a circuit arrangement and a method for reading a capacitive vibratory gyroscope with an at least primary mass and at least one secondary mass that is connected to the primary mass, wherein the primary mass is excited to a primary vibration during operation, and wherein the secondary mass is deflected out of a resting position in a direction that is transversal to the primary vibration when the vibratory gyro-scope rotates around a sensitive axis.

Abstract: A charge balancing circuit is adapted to be connected to an electrode and to a stimulation source. The charge balancing circuit has an electrode terminal for receiving an electrode voltage, an amplifier coupled to the electrode terminal and adapted to amplify and invert the electrode voltage for generating an intermediate voltage and a compensation stage. The compensation stage is adapted to generate an output current if the electrode voltage lies outside a specified safety range and to generate the output current depending on the intermediate voltage. The compensation stage is further adapted to supply the output current to the electrode terminal for driving the electrode voltage towards and/or into the safety range.

Abstract: Riboflavin for use as a medicament in the treatment of a patient with a disease of a diarthrotic, amphiarthrotic or synarthrotic joint, preferably an intervertebral disc disease is provided. The treatment occurs in situ in the patient and includes local administering of riboflavin in a collagenous tissue of the joint and subsequent irradiation with electromagnetic radiation. A method and a kit are also provided for carrying out in-situ crosslinking of a collagenous tissue in the case of a disease of a diarthrotic, amphiarthrotic or synarthrotic joint, preferably an intervertebral disc.

Abstract: A transparent multi-layer assembly includes a transparent carrier structure comprising a polymer material and an electrically conductive transparent layer comprising an electrically conductive oxide. A silicon carbide layer is arranged as an adhesion promoter between the transparent carrier structure and the electrically conductive transparent layer.

Abstract: A polyolefin composition made from or containing (a) a polyolefin and (b) a gibbsite nano platelet treated with a compound of formula (ORa)3Si—Rb or of formula Rc—COOH wherein Ra is a C1-C10 alkyl radical; Rb is a C5-C30 alkyl radical and Rc is a C5-C30 hydrocarbon radical.

Abstract: The present invention relates to a neural implant comprising a biomaterial having an outer surface with a stochastic nanoroughness (Rq), and the application of said stochastic nanoroughness in the diagnosis and/or treatment of a neurological disorder, such as, for example, Parkinson's disease, Alzheimer's disease, glioblastoma and/or for disrupting and/or preventing glial scars in the context of mammalian mechanosensing ion channels selected from the family of PIEZO-1 and PIEZO-2 ion channels.

Abstract: The present invention relates to a neural implant comprising a biomaterial having an outer surface with a stochastic nanoroughness (Rq), and the application of said stochastic nanoroughness in the diagnosis and/or treatment of a neurological disorder, such as, for example, Parkinson's disease, Alzheimer's disease, glioblastoma and/or for disrupting, and/or preventing glial scars in the context of mammalian mechanosensing ion channels selected from the family of PIEZO-1 and PIEZO-2 ion channels.

Abstract: A fluid pump for pumping a fluid from an inlet toward an outlet comprises a pump body, a pump diaphragm, and a valve seat. The pump body has a first opening and a second opening. The pump diaphragm is attached to the pump body and forms a pump chamber between the pump body and the pump diaphragm. The pump chamber is fluidly connected to the inlet by the first opening and to the outlet by the second opening. The valve seat is disposed inside the pump chamber and around the second opening. The valve seat protrudes with an undeformed height from the second opening into the pump chamber in a direction toward the pump diaphragm. The valve seat has an elastic body and a gasket with a sealing surface. The pump diaphragm is deflectable and is adapted to open and close a fluidic pathway of the outlet by moving into and out of contact with the valve seat.

Abstract: The present invention relates to a method for identifying ?T-cell (or ?T-cell) receptors chains or parts thereof that mediate an anti-tumor or anti-infection response by identifying amino acid sequences comprising ?T-cells (or ?T-cell) receptors chains or parts thereof that are shared between different donors.