Abstract: The application of switchable tackiness coating compositions to ophthalmic implants provides the benefits of body temperature tackiness without the disadvantages of room temperature tackiness.

Abstract: Phospholipid-HETE derivatives, compositions and methods of use are disclosed. The compounds are particularly useful for treating dry eye.

Abstract: Compositions containing one or more HETE derivative(s) and an effective concentration of ethanol and methods of use for treating dry eye are disclosed.

Abstract: HETE derivatives and methods of their use for treating dry eye are disclosed.

Abstract: Topically administrable aqueous solution compositions containing tobramycin and xanthan gum are disclosed. The solution compositions contain a buffering agent and a pH-adjusting agent in an amount sufficient to achieve a pH above 7.8 in order to minimize or avoid compatibility problems between tobramycin and xanthan gum.

Abstract: 15-HETE derivatives with enhanced metabolic stability and methods of their use for treating dry eye are disclosed.

Abstract: Methods and compositions for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of systemic mastocytosis are disclosed. The compositions contain a mast cell stabilizing disulfide derivative as an active ingredient.

Abstract: Benzenoid HETE derivatives and methods of their use for treating dry eye are disclosed.

Abstract: The use of polyethoxylated castor oils to treat dry eye disorders is disclosed.

Abstract: Topically administrable anti-allergy compositions comprising olopatadine and a polymeric quaternary ammonium preservative are suitable for use by patients wearing contact lenses.

Abstract: Heteroatom-interrupted HETE derivatives and methods of their use for treating dry eye are disclosed.

Abstract: Pharmaceutical compositions containing a fluoroquinolone antibiotic drug, xanthan gum and a water-soluble calcium salt in an amount sufficient to make the fluoroquinolone antibiotic drug and xanthan gum compatible are disclosed.

Abstract: 3-heteroatom substituted and two carbon homologs of 15-HETE, and their derivatives, compositions and methods of their use for treating dry eye are disclosed.

Abstract: Solution formulations containing a corticosteroid, an antibiotic and a vitamin E tocopheryl derivative as a solubilizing agent are disclosed. The formulations are intended for topical application to the eye, ear, nose or skin.

Abstract: Omega chain modified 15-HETE derivatives and methods of their use for treating dry eye are disclosed.

Abstract: A cassette configuration, operative parts of which may be disposable or resterilizable, is configured with an adapter that may be mounted within the cassette receiving portal of a console that uses a peristaltic pump spaced apart from actuator and vent controls to engage the lower end wall of a cassette. The adapter is asymmetrically mounted in the available space, and allows a tubing loop from one side of a cassette inserted under it to be threaded through the peristaltic pump and to be seated in a bore in the adapter on the opposite side. A lower edge of the cassette fits into an interface slot in the console, and the interior tubing configuration enables clamping of irrigation and vent lines, while providing aspiration and irrigation flows to and from a handpiece. Within the cassette or in the console, flow control elements are provided to enable alternative venting of either air or fluid into the aspiration system to prevent excessive suction at the operative site.

Abstract: 15-HETE derivatives with enhanced metabolic stability and methods of their use for treating dry eye are disclosed.

Abstract: Selective AMPDA inhibitors for preventing and treating damage to the optic nerve and/or retina are disclosed.

Abstract: A peristaltic pump having a molded flow channel contained on an elastomeric sheet that is bonded or mechanically attached to a rigid substrate. The pump head rollers are mounted radially from the axis of rotation of the pump motor and compress the elastomeric flow channels against the rigid substrate.

Abstract: A microsurgical forceps having a first handle and a second handle coupled to the first handle at a hinge point is disclosed. The first handle includes a cannula for transporting surgical fluid and a first jaw with an aperture for delivering the fluid. The second handle includes a second jaw for cooperating with the first jaw. The first handle may include a second cannula for fluidly coupling to a vacuum source. The first jaw may also include a second aperture for delivering vacuum. The forceps may be used to more effectively position an intracorneal optical lens in an intracorneal pocket.