Patents Assigned to Baxter International Inc.
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Patent number: 11129537Abstract: The invention provides a sensor for measuring both impedance and ECG waveforms that is configured to be worn around a patient's neck. The sensor features 1) an ECG system that includes an analog ECG circuit, in electrical contact with at least two ECG electrodes, that generates an analog ECG waveform; and 2) an impedance system that includes an analog impedance circuit, in electrical contact with at least two (and typically four) impedance electrodes, that generates an analog impedance waveform. Also included in the neck-worn system are a digital processing system featuring a microprocessor, and an analog-to-digital converter. During a measurement, the digital processing system receives and processes the analog ECG and impedance waveforms to measure physiological information from the patient. Finally, a cable that drapes around the patient's neck connects the ECG system, impedance system, and digital processing system.Type: GrantFiled: September 30, 2019Date of Patent: September 28, 2021Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Matthew Banet, Susan Meeks Pede, Marshal Singh Dhillon, Kenneth Robert Hunt
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Patent number: 11129929Abstract: Methods and apparatuses for regenerating used dialysis fluid are described herein. In an embodiment, a regenerative dialysis fluid system includes a dialysis unit configured to generate used dialysis fluid including urea, a urea separation unit configured to separate at least a portion of the urea from the used dialysis fluid into a secondary fluid, and a urea removal unit configured to remove at least a portion of the urea from the secondary fluid and return the secondary fluid to the urea separation unit. In an embodiment, the urea separation unit includes a membrane separating a dialysis fluid chamber from a urea chamber, the membrane including at least one of: (i) a positive charge to prevent positive ions from transporting across the membrane; and (ii) a negative charge to prevent negative ions from transporting across the membrane.Type: GrantFiled: November 4, 2019Date of Patent: September 28, 2021Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Cristian Adolfo Menzel Bueno, Yuanpang Samuel Ding, Rosa Yeh
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Patent number: 11123020Abstract: The invention provides a neck-worn sensor that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate the patient's pulse pressure. And from pulse pressure and pulse transit time, a second algorithm, also employing a linear algorithm, can estimate systolic blood pressure and diastolic blood pressure. Thus, the sensor can measure all five vital signs along with hemodynamic parameters. It also includes a motion-detecting accelerometer, from which it can determine motion-related parameters such as posture, degree of motion, activity level, respiratory-induced heaving of the chest, and falls.Type: GrantFiled: December 18, 2015Date of Patent: September 21, 2021Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Matthew Banet, Marshal Singh Dhillon, Susan Meeks Pede, Kenneth Robert Hunt
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Patent number: 11123015Abstract: A stand-on physiological sensor (e.g. floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ECG waveforms. The sensor is similar in configuration to a common bathroom scale and includes electrodes that take electrical measurements from a patient's feet to generate bioimpedance waveforms, which are analyzed digitally to extract various other parameters, as well as a cuff-type blood pressure system that takes physical blood pressure measurements at one of the patient's feet. Blood pressure can also be calculated/derived from the bioimpedance waveforms. Measured parameters are transmitted wirelessly to facilitate remote monitoring of the patient for heart failure, chronic heart failure, end-stage renal disease, cardiac arrhythmias, and other degenerative diseases.Type: GrantFiled: January 28, 2019Date of Patent: September 21, 2021Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Matthew Banet, Marshal Singh Dhillon, Susan Meeks Pede, Lauren Nicole Miller Hayward, Arthur Deptala, Jonas Dean Cochran
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Patent number: 11116696Abstract: A reconstitution device includes: a piercing member having a first end and a second end, the first end of the piercing member configured to engage an administration port; a delivery member having a first end and a second end, the first end of the delivery member configured to engage a delivery site; a collar configured to engage a vial; and a cap extending from the collar and holding the piercing member and the delivery member such that the second end of the piercing member and the second end of the delivery member are disposed within the cylindrical collar.Type: GrantFiled: August 10, 2017Date of Patent: September 14, 2021Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Freddy Desbrosses, Pierpaolo Padula, Virgil Claudiu Manta, Valentin Champain
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Patent number: 11116410Abstract: The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.Type: GrantFiled: July 24, 2018Date of Patent: September 14, 2021Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Erik Tang, Matthew Banet, Marshal Dhillon, James McCanna, Mark Dhillon
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Patent number: 11116895Abstract: An infusion pump is provided for pumping fluid through an administrative set at a desired flow rate over a specified duration, and includes a pumping mechanism for releasably receiving and for exerting a pulsing force on the administrative set, thus pressurizing a portion of the set for creating a flow of fluid from a set outlet. A controller is connected to and is configured for operating the pumping mechanism, the controller determines a pulse frequency based on a volume of fluid infused over a portion of the specified duration and the desired flow rate, outputs a control signal to the pumping mechanism for operating the pumping mechanism based on the determined pulse frequency, determines a first pulse frequency based on the desired flow rate; and adjusts the first pulse frequency based on the volume of fluid infused to provide a second pulse frequency being different from the first pulse frequency.Type: GrantFiled: February 8, 2018Date of Patent: September 14, 2021Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A.Inventors: Patrick Michael Hopkins, Harry John Weber, Haonan Sun
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Publication number: 20210275470Abstract: A packaged, sealed container system for stable storage of a formulation of an oxygen-sensitive pharmaceutical compound, the packaged, sealed container system comprising a primary container including therein a formulation of an oxygen-sensitive pharmaceutical compound, a secondary outer container comprising a first flexible sheet layer, an opposing second flexible sheet layer, and a seal disposed along a common peripheral edge of the first and second flexible sheet layers, such that the primary container is disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. An oxygen scavenger is also disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. The oxygen scavenger is in fluid communication with the contents of the primary container.Type: ApplicationFiled: March 8, 2021Publication date: September 9, 2021Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Steven M. Cope, Allan E. Titus
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Patent number: 11096590Abstract: The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.Type: GrantFiled: July 24, 2018Date of Patent: August 24, 2021Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Erik Tang, Matthew Banet, Marshal Dhillon, James McCanna, Mark Dhillon
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Patent number: 11097041Abstract: Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. The nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The montmorillonite, the bentonite, and the other clays may be used in wearable systems, in which a dialysis fluid is circulated through a filter with the nanoclay sorbents. Waste products are absorbed by the montmorillonite, the bentonite, and the other clays and the dialysis fluid is recycled to a patient's peritoneum. Using an ion-exchange capability of the montmorillonite, the bentonite, and the other clays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate. The nanoclay sorbents are also useful for refreshing a dialysis fluid used in hemodialysis and thus reducing a quantity of the dialysis fluid needed for the hemodialysis.Type: GrantFiled: May 15, 2019Date of Patent: August 24, 2021Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Rosa H. Yeh, Wei Xie, Hsinjin E. Yang, Michael T. K. Ling, Ying-Cheng Lo
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Patent number: 11090421Abstract: Methods, sorbent cartridges and cleaning devices are disclosed for refurbishing sorbent materials. In one implementation among multiple implementations, a medical fluid delivery method includes: providing a sorbent cartridge including H+ZP within a casing for a treatment; and after the treatment, refurbishing the H+ZP while maintained within the casing via (i) regenerating the non-disinfected H+ZP by flowing an acid solution through the casing, (ii) rinsing the regenerated H+ZP while maintained within the casing, (iii) disinfecting the regenerated and rinsed H+ZP by flowing a disinfecting agent through the casing, and (iv) rinsing the regenerated and disinfected H+ZP while maintained within the casing. Multiple batch sorbent refubishing implementations are also disclosed.Type: GrantFiled: November 28, 2018Date of Patent: August 17, 2021Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Yuanpang Samuel Ding, Rosa Hung-Chen Yeh, Cristian Adolfo Menzel Bueno, Ieng Kin Lao
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Patent number: 11092604Abstract: The present invention provides a glucose sensor having a glucose receptor containing a binding site of formula (I): wherein X, n, m and R1 are defined herein. Also provided is a glucose sensor molecule for use in such a glucose sensor, the glucose sensor molecule containing the binding site of formula (I). The binding site has been found to have particularly good selectivity for glucose.Type: GrantFiled: November 19, 2015Date of Patent: August 17, 2021Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Nicholas Paul Barwell, Tony James
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Patent number: 11083827Abstract: A medical fluid delivery system includes: a medical fluid delivery machine including a component having at least one of associated output data or associated test data; at least one of a (i) component output replacement limit and a component output soft limit for the component or (ii) a component testing replacement limit or a component testing soft limit for the component; and a computer programmed to store at least one of (i) or (ii), and for (i) analyze the output data to provide a first indication of how well the component is performing relative to the component output replacement limit and the component output soft limit, and for (ii) analyze the test data to provide a second indication of how well the at least one component is testing relative to the component testing replacement limit and the component testing soft limit.Type: GrantFiled: August 28, 2017Date of Patent: August 10, 2021Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Shawn Collin Oppegard, Marc Alexander Barten
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Patent number: 11071479Abstract: A handheld device measures all vital signs and some hemodynamic parameters from the human body and transmits measured information wirelessly to a web-based system, where the information can be analyzed by a clinician to help diagnose a patient. The system utilizes our discovery that bio-impedance signals used to determine vital signs and hemodynamic parameters can be measured over a conduction pathway extending from the patient's wrist to a location on their thoracic cavity, e.g. their chest or navel. The device's form factor can include re-usable electrode materials to reduce costs. Measurements made by the handheld device, which use the belly button as a ‘fiducial’ marker, facilitate consistent, daily measurements, thereby reducing positioning errors that reduce accuracy of standard impedance measurements. In this and other ways, the handheld device provides an effective tool for characterizing patients with chronic diseases, such as heart failure, renal disease, and hypertension.Type: GrantFiled: October 8, 2018Date of Patent: July 27, 2021Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Matthew Banet, Marshal Singh Dhillon, Susan Meeks Pede, Lauren Nicole Miller Hayward, Arthur Deptala, Jonas Dean Cochran
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Patent number: 11071804Abstract: The present invention provides a hemostatic composite sponge comprising oxidized cellulose and an essentially gelatin-free bioadhesive material stably associated with said sponge and present in an organized pattern on said sponge.Type: GrantFiled: December 15, 2017Date of Patent: July 27, 2021Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Hans Christian Hedrich, Joris Hoefinghoff, Woonza M. Rhee, Atsushi Edward Osawa
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Patent number: 11064918Abstract: The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.Type: GrantFiled: July 24, 2018Date of Patent: July 20, 2021Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Erik Tang, Matthew Banet, Marshal Dhillon, James McCanna
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Patent number: 11058809Abstract: A handheld personal communication apparatus for dialysis includes a reader to (i) read a marking displayed on a dialysis fluid container to acquire data concerning at least one of a dialysis fluid type or a dialysis fluid volume from the marking, and/or (ii) receive a patient weight signal from a weight scale; a processor using at least one of the dialysis fluid type, dialysis fluid volume, or patient weight to determine a dialysis dwell time for at least one cycle of a dialysis therapy, the dialysis dwell time being a time to achieve, over the at least one cycle, at least one of (a) a specified ultrafiltrate level, (b) a urea removal level, or (c) a creatinine removal level; and an output interface providing an indication to the patient of a completion of the dialysis dwell time.Type: GrantFiled: October 21, 2019Date of Patent: July 13, 2021Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Bijan Elahi, Ying-Cheng Lo, Vikram Prabhakar Mehendale
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Patent number: 11058340Abstract: The invention provides a neck-worn sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The neck-worn sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.Type: GrantFiled: July 24, 2018Date of Patent: July 13, 2021Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Erik Tang, Matthew Banet, Marshal Dhillon, James McCanna, Mark Dhillon
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Patent number: 11052183Abstract: The present disclosure provides devices and methods of using same for cleansing a solution (e.g., a salt or used dialysis solution) of urea via electrooxidation, and more specifically to cleansing a renal therapy solution/dialysis solution of urea via electrooxidation so that the renal therapy solution/dialysis solution can be used or reused for treatment of a patient. In an embodiment, a device for the removal of urea from a fluid having urea to produce a cleansed fluid includes a urea decomposition unit and an electrodialysis unit.Type: GrantFiled: August 26, 2019Date of Patent: July 6, 2021Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Yuanpang Samuel Ding, Cristian Adolfo Menzel Bueno, Rosa Yeh
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Patent number: D924157Type: GrantFiled: January 29, 2020Date of Patent: July 6, 2021Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Yochay Kaplan, Baruch Levy, Eliezer Schusman, Mordechai Dinour