Abstract: Doped nitride-based semiconductor materials and methods of producing these materials are described herein.

Abstract: The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described.

Abstract: Methods and apparatuses for using the impedance inhomogeneity pattern (IIP) of a transmission line, or one or more segments thereof, to verify the identity of the transmission line and/or detect whether or not the transmission line has been altered or tampered with. Because the impedance inhomogeneity pattern of a transmission line is unique, unpredictable, and uncontrollable, it can be used as a physical unclonable function (PUF). The IIP can be obtained by a method such as frequency domain reflectometry or time domain reflectometry, and is then compared with a previously stored intrinsic IIP obtained from a transmission line (or segment(s)) prior to first use through the use of, for example, correlation or coherence functions. The method can be used on any transmission line, including electrical, optical and acoustic transmission lines.

Abstract: A water production system including a radiative cooling/heating unit comprising an oscillating heat pipe (OHP) heat spreader. The radiative cooling/heating unit lowers the temperature of the OHP heat spreader below the temperature of the ambient environment. The system additionally including a first OHP heat exchanger thermally connected to the OHP heat spreader such that the first OHP heat exchanger will acquire substantially the same temperature as the OHP heat spreader, a second OHP heat exchanger thermally connected to the OHP heat spreader such that the second OHP heat exchanger will acquire substantially the same temperature as the OHP heat spreader, and a rotatable OHP water absorption bed disposed in thermal contact with the radiative cooling/heating unit such that the OHP absorption bed will acquire substantially the same temperature as the OHP heat spreader.

Abstract: This disclosure relates to synthetic ligands for detecting PD-L1 in a sample or subject. The ligand can be labeled with a variety of detectable labels allowing of visualization and quantification. The ligand provides an alternative PD-L1 binding molecule with advantages over current antibody technologies for detecting PD-L1.

Abstract: Improved sensor compositions comprising a dye are provided. The compositions are generally characterized by at least partially immobilizing the dye on polymeric microparticles and dispersing in a dispersion medium. The dye may comprise an oxygen, humidity, carbon dioxide, temperature, or pH-responsive dye. Also provided is a sensor patch comprising a substrate and the sensor composition comprising a dye.

Abstract: The present disclosure generally relates to smart bandages comprising a dressing and pressure sensor. The pressure sensor measures at least one pressure reading at a wound area while the dressing bandages the wound area. The pressure sensor includes a force sensitive film configured to generate a pressure signal based on pressure applied thereto and is operably coupled to the dressing such that pressure applied to the wound area is coupled to the force sensitive film via the dressing. A near field communication device of the pressure sensor is operably coupled to the force sensitive film for reporting the pressure signal. The smart bandage may include a user interface that is configured to display reported signals to a user for comparing the pressure at the wound area with a threshold pressure. The disclosure further provides a method of treating the wound area by applying the smart bandage to the wound area.

Abstract: A method for forming encapsulated gold nanoparticles mixes mangiferin into a liquid medium to form a reducing agent solution. Gold salts are mixed into the reducing agent solution. Reaction of the gold salts is permitted, in the absence of any other reducing agent, to form a nanoparticle solution of stabilized, biocompatible gold nanoparticles coated with mangiferin. The gold salts can consist of AuCl4, or can consist of radioactive gold salts. A cancer therapy method injects a solution of mangiferin encapsulated gold nanoparticles directly into a solid tumor. A solution consisting of an aqueous or alcoholic medium and mangiferin encapsulated gold nanoparticles is provided. The mangiferin encapsulated gold nanoparticles can have core sizes of ˜5-20 nm and total sizes of ˜20-120 nm.

Abstract: Disclosed herein are example embodiments of a transformative sensor apparatus that is capable of detecting and quantifying the presence of a substance of interest such as a specified bacteria within a sample via changes in impedance exhibited by a detection electrode array. In an example embodiment, sensitivity is improved by including a focusing electrode array in a rampdown channel to focus a concentration of the substance of interest into a detection region. The focusing electrodes include an opposing pair of electrodes in a rampdown orientation. The focusing electrode may also include tilted thin film finger electrodes extending from the rampdown electrodes. In another example embodiment, trapping electrodes are positioned to trap a concentration of the substance of interest onto the detection electrode array.

Abstract: Described herein is the discovery of novel PSMA-specific peptides, which were identified through a novel combinatorial biopanning method. One of the novel PSMA-specific peptides discovered, GTIQPYPFSWGY (or GTI) (SEQ ID NO: 2), exhibits high binding affinity and selectivity to PSMA and PSMA-positive prostate cancer cells. It was found that GTI can mediate internalization of the apoptotic KLA peptide to PSMA-positive LNCaP cells and induce cell death. Moreover, a FAM-labeled GTI peptide shows a high and specific tumor uptake in nude mice bearing human prostate cancer xenografts. It was demonstrated that the GTI peptide can be employed as a PSMA-specific ligand for prostate cancer diagnosis and/or for targeted drug delivery to prostate cancer cells.

Abstract: Herein a Bacillus exosporium antigen delivery (BEAD) system that provides a means to introduce recombinant proteins or small molecules into the exosporium of members of the B. cereus family of bacteria, i.e. B. anthracis, B. cereus, and B. thuringiensis, is disclosed. The system results in the surface display of recombinant proteins or small molecules such that they can stimulate an immune response. In addition, methods of making and using the system are described.

Abstract: An electrochemical reaction cell comprising an anode electrode, a cathode electrode, and a membrane electrode assembly (MEA). The MEA is positioned between the anode electrode and the cathode electrode. The anode electrode, the cathode electrode, and the MEA each have a corrugated shape and are contained within a recess of a housing.

Abstract: The present disclosure provides a new series of compounds exhibiting high fluorescence quantum yields in the solid state. In one embodiment, the compounds include a series of 2,3,4,5-tetraphenylgermoles with the same or different 1,1-substituents. In another embodiment, substituted germafluorenes, germa-fluoresceins/rhodamines, and germapins are described. These germanium heterocycles possess ideal photophysical and thermostability properties, which makes them excellent candidates for chemical or biological sensors, host materials for electroluminescent devices and solar cells, and emissive and/or electron-transport layer components in organic light emitting diode devices.

Abstract: The disclosure relates generally to methods and compositions of treating or preventing diabetes mellitus by administering to a subject a composition comprising an amount of stem and/or progenitor cells and at least one antigen-specific therapy.

Abstract: A resource optimization system is offered for use in managing large scale projects. The resource optimization system has a resource optimization tool configured to receive a plurality of inputs. The plurality of inputs represent at least one task associated with the large scale project and are inputted into a resource optimization tool for a data processing procedure. An optimization module is contained within the resource optimization tool and configured to perform the data processing procedure on each of the plurality of inputs as well as exogenous disturbances inputted into the optimization module. The optimization module returns an optimization result based on the data processing procedure to reflect the management and progress of the project under evaluation.

Abstract: A system and method for performing Optical Coherence Tomography on a sample utilizes collimated, phase modulated beams of light in an interferometer. At least one of the beams of light utilized exists as an Airy beam for at least a portion of the procedure, obviating any deleterious impact caused by the Gaussian beam diffraction. The system may incorporate a light source, polarization beam splitter, delay line, non-polarization beam splitters, lenses, phase masks, waveplates, and mirrors, any or all of which may be controlled by a computing element.

Abstract: A multi-cell electrochemical reaction cell structure for a flow battery or fuel cell having a plurality of cells electrically connected in series or parallel. A first housing has a pair of mating end plates assembled together, each forming a plurality of recesses in which one of the cells is received. One of the end plates has a projection along its perimeter and the other one of the end plates has a groove along its perimeter. The projection is configured to fit within the groove in a mating relationship to seal the housing when the end plates are engaged with each other. A second housing is a tubular shell in which a plurality of tubular flow cell units electrically connected in parallel are housed. Catholyte flows in the tubular flow cell units and anolyte flows in the tubular shell.

Abstract: Carbon dioxide (CO2) capture materials comprising one or more 3D-printed zeolite monoliths for the capture and or removal of CO2 from air or gases in enclosed compartments, including gases or mixtures of gases having less than about 5% CO2. Methods for preparing 3D-printed zeolite monoliths useful as CO2 capture materials and filters, as well as methods of removing CO2 from a gas or mixture of gases in an enclosed compartment using 3D-printed zeolite monoliths are provided.

Abstract: The present invention is directed to a composition that includes an amphiphile, its use in a method of preventing and/or treating cancer, and its use in a method of producing a pharmaceutical composition. In certain embodiments, the amphiphile includes a hydrophilic peptide that binds to a Plenty of SH3 domain (POSH) and inhibits or disrupts a POSH scaffold network, a hydrophobic moiety, and an aptamer. The present invention is also directed to other POSH inhibitor complex biomolecules that do not contain a hydrophobic moiety.

Abstract: High-resolution 3D optical polarization tractography (OPT) images of the internal fiber structure of a target tissue. Manipulation of dual-angle imaging data of the fiber orientation inside a target tissue leads to the determination of 3D imaging properties of the target tissue, allowing transmission of the 3D image properties of the target tissue to an OPT processor to produce high-resolution 3D images.