Patents Assigned to Labrador Diagnostics LLC
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Patent number: 11899010Abstract: The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.Type: GrantFiled: May 24, 2022Date of Patent: February 13, 2024Assignee: Labrador Diagnostics LLCInventors: Tammy Burd, Ian Gibbons, Elizabeth A. Holmes, Gary Frenzel, Anthony Joseph Nugent
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Patent number: 11857966Abstract: Methods and devices are provided for sample collection and sample separation. In one embodiment, a device is provided for use with a formed component liquid sample, the device comprising at least one sample inlet for receiving said sample; at least a first outlet for outputting only a liquid portion of the formed component liquid sample; at least a second outlet for outputting the formed component liquid sample at least a first material mixed therein.Type: GrantFiled: March 15, 2018Date of Patent: January 2, 2024Assignee: Labrador Diagnostics LLCInventors: Deborah Sloan, Channing Robertson
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Patent number: 11802882Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.Type: GrantFiled: December 17, 2018Date of Patent: October 31, 2023Assignee: Labrador Diagnostics LLCInventors: Ian Gibbons, Shaunak Roy, Edmond Ku
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Patent number: 11767547Abstract: Methods and compositions for the amplification of nucleic acids and generation of concatemers are disclosed. Amplification methods provided herein may be performed under isothermal conditions. Methods and compositions may include reagents such as nucleic acid polymerases and primers.Type: GrantFiled: October 3, 2019Date of Patent: September 26, 2023Assignee: Labrador Diagnostics LLCInventors: Kamila Belhocine, Josephine Lee, Pranav Patel, Aaron Richardson, Scott Tabakman
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Patent number: 11754554Abstract: The present invention provides fluidic devices and systems that allow detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.Type: GrantFiled: January 11, 2017Date of Patent: September 12, 2023Assignee: Labrador Diagnostics LLCInventors: Shaunak Roy, Melissa Takahashi, Ian Gibbons, Edmond Ku, Thanh Dang, Tammy Burd, Adam Vollmer, Elizabeth A. Holmes
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Patent number: 11649487Abstract: Methods and compositions for the amplification of nucleic acids and generation of concatemers are disclosed. Amplification methods provided herein may be performed under isothermal conditions. Methods and compositions may include reagents such nucleic acid polymerases and primers.Type: GrantFiled: August 6, 2020Date of Patent: May 16, 2023Assignee: Labrador Diagnostics LLCInventors: Kamila Belhocine, Josephine Lee, Pranav Patel, Aaron Richardson, Scott Tabakman
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Patent number: 11644410Abstract: The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.Type: GrantFiled: December 28, 2020Date of Patent: May 9, 2023Assignee: Labrador Diagnostics LLCInventors: Anthony J. Nugent, Daniel L. Young, Elizabeth A. Holmes, Michael Siegel, Ryan Wistort
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Patent number: 11630069Abstract: This invention is in the field of medical devices. Specifically, the present invention provides fluidic systems having a plurality of reaction sites surrounded by optical barriers to reduce the amount of optical cross-talk between signals detected from various reaction sites. The invention also provides a method of manufacturing fluidic systems and methods of using the systems.Type: GrantFiled: August 29, 2017Date of Patent: April 18, 2023Assignee: Labrador Diagnostics LLCInventors: Timothy Michael Kemp, Chris Todd, Ron Oral, Shulin Zeng, John Howard, Jeff Fenton, Elizabeth A. Holmes, Ian Gibbons, Shaunak Roy
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Patent number: 11603558Abstract: Methods and compositions for the amplification of nucleic acids and generation of concatemers are disclosed. Amplification methods provided herein may be performed under isothermal conditions. Methods and compositions may include reagents such as nucleic acid polymerases and primers.Type: GrantFiled: November 14, 2018Date of Patent: March 14, 2023Assignee: Labrador Diagnostics LLCInventors: Kamila Belhocine, Josephine Lee, Pranav Patel, Aaron Richardson, Scott Tabakman
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Patent number: 11545241Abstract: Systems, methods, and devices are provided for clinical laboratory testing using less than 1 mL of sample collected from a subject. Some embodiments collect between 1 mL and about 10 uL of sample from a subject. A method is also provided for analyte testing, wherein a mobile computing device may be used for laboratory test requests and for handling of the analyte testing process.Type: GrantFiled: September 8, 2014Date of Patent: January 3, 2023Assignee: Labrador Diagnostics LLCInventors: Elizabeth A. Holmes, Sunny Balwani, Daniel Young
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Patent number: 11524299Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.Type: GrantFiled: December 12, 2019Date of Patent: December 13, 2022Assignee: Labrador Diagnostics LLCInventors: Elizabeth A. Holmes, Joy Roy, John Kent Frankovich, Daniel L. Young, Timothy Smith, Chinmay Pangarkar, Samartha Anekal
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Patent number: 11442061Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications. In particular, the medical device reduces interference with an optical signal which is indicative of the presence of an analyte in a bodily sample.Type: GrantFiled: April 12, 2018Date of Patent: September 13, 2022Assignee: Labrador Diagnostics LLCInventors: Ian Gibbons, Michael O'Connell
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Publication number: 20220252503Abstract: The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.Type: ApplicationFiled: December 13, 2021Publication date: August 11, 2022Applicant: Labrador Diagnostics LLCInventors: Ian GIBBONS, Anthony NUGENT, Anthony DELACRUZ, Daniel YOUNG, Elizabeth A. HOLMES, Andrew DRAKE, Timothy Michael KEMP, Sunny BALWANI, Chinmay PANGARKAR
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Patent number: 11385252Abstract: In one embodiment, a method is provided comprising analyte testing on one or more types of samples.Type: GrantFiled: August 15, 2019Date of Patent: July 12, 2022Assignee: Labrador Diagnostics LLCInventors: Elizabeth A. Holmes, Timothy Smith, Alexander Loo, Daniel Young
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Publication number: 20220196639Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications. In particular, the medical device reduces interference with an optical signal which is indicative of the presence of an analyte in a bodily sample.Type: ApplicationFiled: January 3, 2022Publication date: June 23, 2022Applicant: Labrador Diagnostics LLCInventors: Ian Gibbons, Michael O'Connell
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Publication number: 20220196657Abstract: The present invention provides system and methods for detecting an analyte indicative of an influenza viral infection in a sample of bodily fluid. The present invention also provides for systems and method for detection a plurality of analytes, at least two of which are indicative of an influenza viral infection in a sample of bodily fluid.Type: ApplicationFiled: November 1, 2021Publication date: June 23, 2022Applicant: Labrador Diagnostics LLCInventors: Elizabeth A. Holmes, Ian Gibbons
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Patent number: 11366106Abstract: The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.Type: GrantFiled: March 14, 2016Date of Patent: June 21, 2022Assignee: LABRADOR DIAGNOSTICS LLCInventors: Tammy Burd, Ian Gibbons, Elizabeth A. Holmes, Gary Frenzel, Anthony Joseph Nugent
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Patent number: 11360107Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.Type: GrantFiled: February 25, 2015Date of Patent: June 14, 2022Assignee: Labrador Diagnostics LLCInventors: Daniel Young, Samartha Anekal, Elizabeth A. Holmes, Timothy Smith, Chinmay Pangarkar, James R. Wasson
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Patent number: 11320355Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.Type: GrantFiled: January 28, 2019Date of Patent: May 3, 2022Assignee: Labrador Diagnostics LLCInventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
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Patent number: 11323345Abstract: Methods and systems are provided for connecting an electronic device to a network. In some situations, the electronic device connects to a first network provider and pings a first server having a static internet protocol address and a second server having a dedicated uniform resource locator. If the electronic device receives a response from the first and second server, the electronic device maintains its connection to the first network provider. Otherwise, the electronic device connects to a second network provider and pings the first and second servers.Type: GrantFiled: September 5, 2019Date of Patent: May 3, 2022Assignee: Labrador Diagnostics LLCInventor: Sunny Balwani