Patents Assigned to LightLab Imaging, Inc.
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Publication number: 20240163404Abstract: The disclosure relates to a modular data acquisition and processing system for obtaining intravascular data, such as image data, for a patient. The modular system includes acquisition components in a patient procedure environment in communication with a processing engine in a remote environment. The remote processing engine may be used with different types of data acquisition systems. The modular system further includes a hub in the patient procedure environment, which maintain a persistent connection with the remote processing engine while enabling fast and reliable coupling to data acquisition components.Type: ApplicationFiled: November 9, 2023Publication date: May 16, 2024Applicant: LightLab Imaging, Inc.Inventors: Tomas Russ, Steven M. Stromski, Samir Farah, Mark Hoeveler, Douglas Tatosian
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Publication number: 20240130793Abstract: In part, the disclosure relates to determining a stent deployment location and other parameters using blood vessel data. Stent deployment can be planned such that the amount of blood flow restored from stenting relative to an unstented vessel increases one or more metrics. An end user can specify one or more stent lengths, including a range of stent lengths. In turn, diagnostic tools can generate candidate virtual stents having lengths within the specified range suitable for placement relative to a vessel representation. Blood vessel distance values such as blood vessel diameter, radius, area values, chord values, or other cross-sectional, etc. its length are used to identify stent landing zones. These tools can use or supplement angiography data and/or be co-registered therewith. Optical imaging, ultrasound, angiography or other imaging modalities are used to generate the blood vessel data.Type: ApplicationFiled: December 7, 2023Publication date: April 25, 2024Applicant: LightLab Imaging, Inc.Inventor: Ajay Gopinath
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Publication number: 20240115141Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.Type: ApplicationFiled: November 30, 2023Publication date: April 11, 2024Applicant: LightLab Imaging, Inc,Inventors: Joseph M. Schmitt, Joel M. Friedman, Christopher Petroff, Amr Elbasiony
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Publication number: 20240099591Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.Type: ApplicationFiled: November 30, 2023Publication date: March 28, 2024Applicant: LightLab Imaging, Inc.Inventors: Joseph M. Schmitt, Joel M. Friedman, Christopher Petroff, Amr Elbasiony
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Publication number: 20240099590Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.Type: ApplicationFiled: November 29, 2023Publication date: March 28, 2024Applicant: LightLab Imaging, Inc.Inventors: Joseph M. Schmitt, Joel M. Friedman, Christopher Petroff, Amr Elbasiony
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Patent number: 11923067Abstract: In part, the invention relates to a method for sizing a stent for placement in a vessel. In one embodiment, the method includes the steps of: dividing the vessel into a plurality of segments, each segment being defined as the space between branches of the vessel; selecting a starting point that appears to have substantially no disease; defining the diameter at this point to be the maximum diameter; calculating the maximal diameter of the next adjacent segment according to a power law; measuring the actual diameter of the next adjacent segment; selecting either the calculated maximum diameter or the measured maximum diameter depending upon which diameter is larger; using the selected maximum diameter to find the maximum diameter of this next segment; iteratively proceeding until the entire length of the vessel is examined; and selecting a stent in response to the diameters of the end proximal and distal segments.Type: GrantFiled: March 12, 2013Date of Patent: March 5, 2024Assignee: LightLab Imaging, Inc.Inventors: Joseph M. Schmitt, Hiram Bezerra, Christopher Petroff, Ajay Gopinath
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Publication number: 20240057870Abstract: In part, the disclosure relates to method of displaying a representation of an artery. The method may include storing an intravascular image dataset in a memory device of a diagnostic imaging system, the intravascular image dataset generated in response to intravascular imaging of a segment of an artery; automatically detecting lumen boundary of the segment on a per frame basis; automatically detecting EEL and displaying a stent sizing workflow. In part, the disclosure also relates to automatically detecting one or more regions of calcium relative to lumen boundary of the segment; calculating an angular or circumferential measurement of detected calcium for one or more frames; calculating a calcium thickness of detected calcium for one or more frames; and displaying the calcium thickness and the angular or circumferential measurement of detected calcium for a first frame of the one or more frames.Type: ApplicationFiled: October 31, 2023Publication date: February 22, 2024Applicant: LightLab Imaging, Inc.Inventors: Ajay Gopinath, Mark Hoeveler
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Publication number: 20240046476Abstract: The present disclosure provides systems and methods to receiving OCT or IVUS image data frames to output one or more representations of a blood vessel segment. The image data frames may be stretched and/or aligned using various windows or bins or alignment features. Arterial features, such as the calcium burden, may be detected in each of the image data frames. The arterial features may be scored. The score may be a stent under-expansion risk. The representation may include an indication of the arterial features and their respective score. The indication may be a color coded indication.Type: ApplicationFiled: October 10, 2023Publication date: February 8, 2024Applicant: LightLab Imaging, Inc.Inventors: Gregory Patrick Amis, Ajay Gopinath, Mark Hoeveler
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Patent number: 11892291Abstract: Aspects of the disclosure relate to systems, methods, and algorithms to perform wavenumber linearization and dispersion correction in optical systems without the need for hardware modifications, empirical adjustments, precise mirror alignment, and which can be conducted at low computational costs and in real-time. A one-time calibration process can generate spectra or calibration criteria, including wavenumber-linearization criteria, dispersion correction, and spectral flattening spectra, which can be used to correct an optical coherence tomogram in real time.Type: GrantFiled: February 8, 2022Date of Patent: February 6, 2024Assignee: LightLab Imaging, Inc.Inventors: Chih-Hao Liu, Steven M. Stromski
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Publication number: 20240032894Abstract: In part, the disclosure relates to computer-based methods, devices, and systems suitable for detecting a delivery catheter using intravascular data. In one embodiment, the delivery catheter is used to position the intravascular data collection probe. The probe can collect data suitable for generating one or more representations of a blood vessel with respect to which the delivery catheter can be detected.Type: ApplicationFiled: October 5, 2023Publication date: February 1, 2024Applicant: LightLab Imaging, Inc.Inventors: James G. Peterson, Christopher E. Griffin, Sonal Ambwani
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Publication number: 20240036720Abstract: In part, the disclosure relates to intravascular data collection systems and the software-based visualization and display of intravascular data relating to detected side branches and side branch obstruction. An estimate of side branch diameter can be made based on a vessel profile or a maximum diameter of a vessel at a distal and proximal location relative to the side branch. A amount of side branch obstruction may be determined by comparing an observed side branch diameter with in the image data with the estimated side branch diameter. In addition, an amount of blood flow obstruction may also be determined.Type: ApplicationFiled: August 15, 2023Publication date: February 1, 2024Applicant: LightLab Imaging, Inc.Inventors: Ajay Gopinath, Denis Dion, Christopher E. Griffin, Desmond Adler
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Patent number: 11883107Abstract: In part, the disclosure relates to determining a stent deployment location and other parameters using blood vessel data. Stent deployment can be planned such that the amount of blood flow restored from stenting relative to an unstented vessel increases one or more metrics. An end user can specify one or more stent lengths, including a range of stent lengths. In turn, diagnostic tools can generate candidate virtual stents having lengths within the specified range suitable for placement relative to a vessel representation. Blood vessel distance values such as blood vessel diameter, radius, area values, chord values, or other cross-sectional, etc. its length are used to identify stent landing zones. These tools can use or supplement angiography data and/or be co-registered therewith. Optical imaging, ultrasound, angiography or other imaging modalities are used to generate the blood vessel data.Type: GrantFiled: September 28, 2017Date of Patent: January 30, 2024Assignee: LightLab Imaging, Inc.Inventor: Ajay Gopinath
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Publication number: 20230414176Abstract: A method and apparatus for determining properties of a tissue or tissues imaged by optical coherence tomography (OCT). In one embodiment the backscatter and attenuation of the OCT optical beam is measured and based on these measurements and indicium such as color is assigned for each portion of the image corresponding to the specific value of the backscatter and attenuation for that portion. The image is then displayed with the indicia and a user can then determine the tissue characteristics. In an alternative embodiment the tissue characteristics is classified automatically by a program given the combination of backscatter and attenuation values.Type: ApplicationFiled: September 13, 2023Publication date: December 28, 2023Applicant: LightLab Imaging, Inc.Inventors: Joseph M. Schmitt, Chenyang Xu
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Publication number: 20230414314Abstract: In one embodiment, the disclosure relates to a probe that a cylindrical marker band defining an inner surface, an outer surface, a first end and a second end and having a band length, the inner surface defining a marker band bore, the cylindrical marker band includes a radiopaque material; a molded unitary lens defining an elongate optical fiber receiving section having a fiber section length and a beam directing surface, wherein the fiber section length and the band length overlap along an overlap distance; and an optical fiber, wherein a first section of the optical fiber is disposed in the optical fiber receiving section, wherein a portion of the first section of the optical fiber is disposed within the marker band bore.Type: ApplicationFiled: September 8, 2023Publication date: December 28, 2023Applicant: LightLab Imaging, Inc.Inventors: James Booker, David Ellman, Douglas Tatosian, Charles Milne
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Patent number: 11850089Abstract: In part, the disclosure relates to computer-based methods, devices, and systems suitable for detecting a delivery catheter using intravascular data. In one embodiment, the delivery catheter is used to position the intravascular data collection probe. The probe can collect data suitable for generating one or more representations of a blood vessel with respect to which the delivery catheter can be detected.Type: GrantFiled: May 8, 2020Date of Patent: December 26, 2023Assignee: LightLab Imaging, Inc.Inventors: James G. Peterson, Christopher E. Griffin, Sonal Ambwani
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Publication number: 20230389799Abstract: In part, the disclosure relates to method of displaying a representation of an artery. The method may include storing an intravascular image dataset in a memory device of a diagnostic imaging system, the intravascular image dataset generated in response to intravascular imaging of a segment of an artery; automatically detecting lumen boundary of the segment on a per frame basis; automatically detecting EEL and displaying a stent sizing workflow. In part, the disclosure also relates to automatically detecting one or more regions of calcium relative to lumen boundary of the segment; calculating an angular or circumferential measurement of detected calcium for one or more frames; calculating a calcium thickness of detected calcium for one or more frames; and displaying the calcium thickness and the angular or circumferential measurement of detected calcium for a first frame of the one or more frames.Type: ApplicationFiled: August 24, 2023Publication date: December 7, 2023Applicant: LightLab Imaging, Inc.Inventors: Ajay Gopinath, Mark Hoeveler
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Patent number: 11819309Abstract: In part, the disclosure relates to method of displaying a representation of an artery. The method may include storing an intravascular image dataset in a memory device of a diagnostic imaging system, the intravascular image dataset generated in response to intravascular imaging of a segment of an artery; automatically detecting lumen boundary of the segment on a per frame basis; automatically detecting EEL and displaying a stent sizing workflow. In part, the disclosure also relates to automatically detecting one or more regions of calcium relative to lumen boundary of the segment; calculating an angular or circumferential measurement of detected calcium for one or more frames; calculating a calcium thickness of detected calcium for one or more frames; and displaying the calcium thickness and the angular or circumferential measurement of detected calcium for a first frame of the one or more frames.Type: GrantFiled: March 17, 2020Date of Patent: November 21, 2023Assignee: LightLab Imaging, Inc.Inventors: Ajay Gopinath, Mark Hoeveler
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Patent number: 11793462Abstract: A method and apparatus for determining properties of a tissue or tissues imaged by optical coherence tomography (OCT). In one embodiment the backscatter and attenuation of the OCT optical beam is measured and based on these measurements and indicium such as color is assigned for each portion of the image corresponding to the specific value of the backscatter and attenuation for that portion. The image is then displayed with the indicia and a user can then determine the tissue characteristics. In an alternative embodiment the tissue characteristics is classified automatically by a program given the combination of backscatter and attenuation values.Type: GrantFiled: March 6, 2018Date of Patent: October 24, 2023Assignee: LightLab Imaging, Inc.Inventors: Joseph M. Schmitt, Chenyang Xu
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Publication number: 20230326032Abstract: In part, the disclosure relates to methods, and systems suitable for evaluating image data from a patient on a real time or substantially real time basis using machine learning (ML) methods and systems. Systems and methods for improving diagnostic tools for end users such as cardiologists and imaging specialists using machine learning techniques applied to specific problems associated with intravascular images that have polar representations. Further, given the use of rotating probes to obtain image data for OCT, IVUS, and other imaging data, dealing with the two coordinate systems associated therewith creates challenges. The present disclosure addresses these and numerous other challenges relating to solving the problem of quickly imaging and diagnosis a patient such that stenting and other procedures may be applied during a single session in the cath lab.Type: ApplicationFiled: June 1, 2023Publication date: October 12, 2023Applicant: LightLab Imaging, Inc.Inventors: Shimin Li, Ajay Gopinath, Kyle Savidge
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Publication number: 20230306620Abstract: The disclosure relates to methods of providing live x-ray images such as fluoroscopic images in combination with reference information co-registered angiography frames that are motion corrected in real time. In part, the disclosure describes an improvement on the existing workflow where the user must remember where the vessel features from OCT are and use a reference frame to estimate the location of desired stent placement. Disclosed herein are methods to correlate the live imaging feed and the reference angiography image such that the user may dynamically zoom and pan the live imaging feed and the reference angiography image.Type: ApplicationFiled: March 23, 2023Publication date: September 28, 2023Applicant: LightLab Imaging, Inc.Inventors: Angela Zhang, Shimin Li, Robert Steinbrecher, Jack Fince, Paul Gervasio