Abstract: Disclosed are fluorescent markers that include a known number of copies of a fluorescently-labeled protein regularly interspersed along the length of the fluorescent marker. The fluorescent markers may be used to quantify fluorescently-labeled samples in fluorescent microscopy.

Abstract: Passive wireless sensors include an antenna. The antenna receives a combined signal. The combined signal includes a low frequency modulating signal modulated on a high frequency carrier wave. A demodulator receives the combined signal and extracts the modulating signal. A sensor receives the extracted modulating signal and produces an output signal with a time delay indicative of a property to be sensed. A modulator receives the output signal and the high frequency carrier wave and modulates the output signal onto the high frequency carrier wave to create a combined output signal broadcast by the antenna.

Abstract: An anchoring device for securing objects within a rack mount system using fasteners. The anchoring device has a base portion with flush and anchor faces, the anchor faces defining apertures. Hooks are provided for securing the anchoring device to the rack mount system. Each hook has a horizontal arm with base and distal ends, and a vertical arm with upper and lower ends. Each base end is coupled to the anchor face and each distal end is coupled to the upper end of one vertical arm. Hooks are receivable within openings in the rack mount system to secure the anchoring device. The apertures in the base portion align with the openings in the rack mount system when the anchoring device is secured to the rack mount system such that the object is securable to the rack mount system by engaging the fasteners with the apertures in the anchoring device.

Abstract: A device for processing a surface of a work piece. A motor is configured to produce a rotary force. A driving pulley is operatively coupled to the motor such that the rotary force produced by the motor causes rotation of the driving pulley. A belt is operatively coupled to the driving pulley such that rotation of the driving pulley causes rotation of the belt. A second pulley is also operatively coupled to the belt such that rotation of the belt causes rotation of the second pulley. Bristles are coupled to the belt and extend away from the belt. The rotary force produced by the motor causes the plurality of bristles to move relative to the motor. The surface of the work piece is processed when the bristles contacts the surface while the bristles are moving.

Abstract: An ankle prosthesis comprises a foot prosthesis. A lower ankle is pivotably secured to the foot prosthesis at an ankle joint. An upper ankle is connected to the lower ankle in a manner that permits vertical movement of the upper ankle relative to the lower ankle. A coupling spring is biased in an extended condition. The coupling spring is connected at a first end to the upper ankle. A second end of the coupling spring is movable in a first condition which is engaged to the lower ankle and in a second condition engaged to the foot prosthesis. Energy is stored in compression of the coupling spring when the coupling spring is in the first condition and energy is released from the coupling spring when the coupling spring is in the second condition.

Abstract: Passive wireless sensors include an antenna. The antenna receives a combined signal. The combined signal includes a low frequency modulating signal modulated on a high frequency carrier wave. A demodulator receives the combined signal and extracts the modulating signal. A sensor receives the extracted modulating signal and produces an output signal with a time delay indicative of a property to be sensed. A modulator receives the output signal and the high frequency carrier wave and modulates the output signal onto the high frequency carrier wave to create a combined output signal broadcast by the antenna.

Abstract: An exemplary embodiment of a method of detecting hydrocarbons in Systems and methods for sensing analytes in an aqueous solution, include pretreating a water sample to provide a test sample. A flow cell includes at least one sensor with a polymer coating having at least partial selectivity for at least one analyte. The flow cell receives a test sample and a reference sample. At least one output signal from the at least one sensor is processed with a microcontroller using a model of the sensor response and a bank of Kalman filters to estimate a concentration of at least one analyte in the aqueous solution.

Abstract: Systems and methods of diagnosing open-circuit fault in power converters receives a neutral point current value, a switching state of the power converter, and load current values. At least one fault condition is identified based upon the switching state of the power converter and the load current values. The neutral point current value current value is compared to the at least one fault condition.

Abstract: Split-crank pedaling devices and methods of operation support patient use and rehabilitation, particularly for stroke patients. A split-crank pedaling device includes first and second crank assemblies. First and second motors are operably connected to the first and second crank assemblies. A first shaft sensor produces an indication of a position of the shaft of the first crank assembly. A second shaft sensor produces an indication of a position of the shaft of the second crank assembly. A controller is communicatively connected to the first and second motors and the first and second shaft sensors and calculates a phase error between the positions of the first and second shafts and a predetermined phase relationship between the first and second shafts. The controller operates at least one of the first motor or the second motor to provide a supplemental torque to one of the first crank assembly and the second crank assembly.

Abstract: Systems and methods of fault tolerant power conversion include an inverter with a plurality of inverter phase legs. Each phase leg includes a positive switch, a negative switch, and a bi-directional midpoint switch. Redundant phase leg includes a positive redundant switch connected between the positive switches and the bi-directional midpoint switches. The redundant phase leg includes a negative redundant switch connected between the negative switches and the bi-directional midpoint switches. Upon detection of a fault condition in at least one switch of the plurality of inverted phase legs, one of the positive redundant switch and the negative redundant switch is closed to bypass at least one switch with the fault condition to maintain operation of the power converter.

Abstract: Devices for controlling movement of aerial buckets via hydraulic systems. Each hydraulic system has valves that control movement of the aerial bucket. A control head of the device has a joystick that is moveable and encoders that detect movement of the joystick. A valve actuator manifold of the device is coupled between the control head and the hydraulic system and supports valve actuators moveably coupled to the valves. Servo drive systems supported by the valve actuator manifold are coupled to the valve actuators and are controllable to move the valve actuators. A processor module of the device is in communication with the encoders and the servo drive systems. The processor module controls the servo drive systems based on input from the encoders such that moving the joystick controls movement of the aerial bucket.

Abstract: Disclosed are substituted (4?-hydroxylphenyl)cycloalkane compounds and there use as selective agonists of the estrogen receptor beta isoform (ER?). The disclosed compounds may be formulated as pharmaceutical compositions and administered to treat diseases associated with ER activity, such as proliferative diseases and disorders and/or psychiatric diseases or disorders.

Abstract: Split-crank pedaling devices and methods of operation support patient use and rehabilitation, particularly for stroke patients. A split-crank pedaling device includes first and second crank assemblies. First and second motors are operably connected to the first and second crank assemblies. A first shaft sensor produces an indication of a position of the shaft of the first crank assembly. A second shaft sensor produces an indication of a position of the shaft of the second crank assembly. A controller is communicatively connected to the first and second motors and the first and second shaft sensors and calculates a phase error between the positions of the first and second shafts and a predetermined phase relationship between the first and second shafts. The controller operates at least one of the first motor or the second motor to provide a supplemental torque to one of the first crank assembly and the second crank assembly.

Abstract: Disclosed herein is a prosthesis that may be used to replace standard prosthetic material used in osteo-odonto-keratoprosthesis (OOKP) surgery. The disclosed prosthesis is not prepared from tissue removed from a patient's tooth and jaw bone, but rather is a synthetic prosthesis. The synthetic prosthesis typically includes a solid part for supporting an optical cylinder and a porous part that facilitates bio-integration of the implanted prosthesis into the patient's eye.

Abstract: Disclosed are systems and methods of sensor fusion for exemplary use with robotic navigation control. Systems and methods include providing local estimates of a target location from a plurality of expert modules that process sensor data. The local estimates are weighted based upon a Mahalanobis distance from an expected estimated value and based upon a Euclidean distance between the local estimates. The local estimates are fused in a Bayesian fusion center based upon the weight given to each of the local estimates.

Abstract: Indoline sulfonamide compounds that can inhibit DapE and/or bacterial metallo-?-lactamases (MBLs), such as NDM-1, are disclosed. Also disclosed are methods of treating an individual suffering from a bacterial infection using the indoline sulfonamide compounds disclosed herein.

Abstract: An ankle prosthesis comprises a foot prosthesis. A lower ankle is pivotably secured to the foot prosthesis at an ankle joint. An upper ankle is connected to the lower ankle in a manner that permits vertical movement of the upper ankle relative to the lower ankle. A coupling spring is biased in an extended condition. The coupling spring is connected at a first end to the upper ankle. A second end of the coupling spring is movable in a first condition which is engaged to the lower ankle and in a second condition engaged to the foot prosthesis. Energy is stored in compression of the coupling spring when the coupling spring is in the first condition and energy is released from the coupling spring when the coupling spring is in the second condition.

Abstract: Scaffolds for use in bone tissue engineering include a skeleton and a host component. Methods of preparation of scaffolds include identification of biodegradation properties for the skeleton and the host component. The skeleton is constructed to form a three-dimensional shape. The skeleton is constructed of a first material and has a first rate of biodegradation. The host component fills the three-dimensional shape formed by the skeleton. The host component is constructed of a second material and has a second rate of biodegradation. The first rate of biodegradation is slower than the second rate of biodegradation.

Abstract: Disclosed herein are composite materials, ionic liquid compositions for preparing the composite materials, and methods for using the composite materials prepared from the ionic liquid compositions. The composite materials typically include structural polysaccharides, structural proteins, and optionally including metal or metal oxide particles. The composite materials may be prepared from ionic liquid compositions comprising the structural polysaccharides, structural proteins, and the optional metal or metal oxide particles, where the ionic liquid is removed from the ionic liquid compositions to obtain the composite materials.

Abstract: Methods and systems for rating fiduciaries that govern assets. Governance variables relating to governing the assets that the impact performance of the assets are collected. Control variables that also impact the performance are assigned. A collection of actual test values are compiled for the governance variables, the control variables, and the performance for test assets within the assets. A weight factor indicating the impacts on the performance by each of the governance variables and the control variables is assigned. A rating model incorporating the governance variables and the control variables and each respective weight factor is constructed. Actual asset values for the governance variables and the control variables for a given asset within the assets are collected. A given fiduciary within the fiduciaries that governs the given asset is rated using the rating model with the actual asset values collected.