Patents Assigned to Nikkiso Company Limited
  • Patent number: 11529078
    Abstract: This fluid evaluation device is provided with an irradiation unit for irradiating a fluid with light, a light reception unit for receiving scattered light from the fluid and outputting a light reception signal, and an estimation unit for estimating at least one from among flow rate and density by mapping input points, which are on a first plane defined by flow rate and frequency and are expressed by light amount information indicating the amount of scattered light included in the light reception signal and frequency information indicating a frequency for a beat signal resulting from the Doppler shifting of the light included in the light reception signal, onto a second plane defined by fluid flow rate and fluid density.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: December 20, 2022
    Assignees: AIR WATER BIODESIGN INC., NIKKISO COMPANY LIMITED
    Inventors: Kiyoshi Tateishi, Wataru Onodera, Atsuya Ito, Tomoya Murakami, Akari Agata, Genki Adachi
  • Patent number: 11486892
    Abstract: This fluid measuring device is provided with: an irradiation unit that irradiates a fluid with light; a light receiving unit that receives light scattered by the fluid; a detecting unit that detects a backflow of the fluid on the basis of a light reception signal from the light receiving unit; and a calculating unit that calculates, on the basis of the detection result by the detection unit and the light reception signal from the light receiving unit, estimated fluid information indicating the flow rate or flow speed of the fluid. Accordingly, even when a backflow of the fluid temporarily occurs, the flow speed of the fluid can be precisely measured.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: November 1, 2022
    Assignees: AIR WATER BIODESIGN INC., NIKKISO COMPANY LIMITED
    Inventors: Kiyoshi Tateishi, Wataru Onodera, Atsuya Ito, Tomoya Murakami, Akari Agata, Genki Adachi
  • Patent number: 11480981
    Abstract: This temperature control device is provided with: an endothermic/exothermic unit that heats or cools a subject to be subjected to temperature control; a temperature detection unit that detects the first temperature of the periphery of the subject; a control unit that controls the endothermic/exothermic unit on the basis of a variable target temperature; and a variable target temperature setter that sets the variable target temperature to a first variable target temperature on the basis of the first temperature and target temperature information indicating the target temperature. With such temperature control device, since the target temperature changes to a suitable value as needed, a time needed until the temperature of the subject reaches the target temperature can be shortened.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: October 25, 2022
    Assignees: AIR WATER BIODESIGN INC., NIKKISO COMPANY LIMITED
    Inventors: Tadashi Kondo, Kiyoshi Tateishi, Tomoya Murakami, Akari Agata, Genki Adachi
  • Patent number: 11478885
    Abstract: A method of manufacturing a medical device including a case having a first and a second case portion mated together. The case having a space inside and an elastic membrane attached to the case. A first housing space covered by the first case portion and a second housing space covered by the second case portion. Fixing parts at peripheries of the first and the second case portions and at which the first and the second case portions are mated. Holding surfaces at the peripheries of the first and the second case portions. A sealing part at the periphery of the first or the second ease portions with respect to the fixing parts and that seals an entirety of the peripheral edge of the elastic membrane. Forming an air gap between the sealing part and the fixing parts by depressurization or heating the fixing parts that connect the case portions.
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: October 25, 2022
    Assignee: Nikkiso Company Limited
    Inventors: Shingo Okamoto, Hiroyuki Kawajiri, Kosei Nishida
  • Patent number: 11471574
    Abstract: A blood-purification-treatment support system is capable of making an accurate judgement of whether or not any treatment conditions for blood purification treatment should be changed. The blood-purification-treatment support system is capable of supporting blood purification treatment. The system includes a storage device that stores patient-specific patient data that are acquired on a plurality of days including at least no-treatment days on which blood purification treatment is not conducted, an estimating device that compares the patient data for the plurality of days stored in the storage device with one another and estimates a pre-treatment patient state regarding blood purification treatment, and a judging device that judges from the pre-treatment patient state estimated by the estimating device whether or not any treatment conditions for blood purification treatment should be changed.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: October 18, 2022
    Assignee: Nikkiso Company Limited
    Inventors: Hitoshi Goto, Kunihiko Akita, Masahiro Toyoda
  • Patent number: 11458238
    Abstract: A blood purification apparatus is provided that is capable of detecting an abnormal state of puncture into a blood vessel with an arterial puncture needle or a venous puncture needle.
    Type: Grant
    Filed: January 15, 2020
    Date of Patent: October 4, 2022
    Assignee: Nikkiso Company Limited
    Inventors: Hitoshi Goto, Masahiro Toyoda, Tomoya Murakami, Kunihiko Akita
  • Patent number: 11458237
    Abstract: A blood purification apparatus that detects dislodgement of a puncture needle is provided. The apparatus includes an arterial electrode, a venous electrode, a power source capable of causing a current to flow through an arterial puncture needle and a venous puncture needle that are stuck in a patient, a body-surface electrode closely attached to a body surface of the patient, a detection device capable of acquiring a heart rate of the patient in accordance with an electrical signal detected by the body-surface electrode, a monitoring device capable of monitoring in real time the current flowing through the arterial electrode or the venous electrode and a change in an impedance in a body of the patient that is detected by the detection device, and an identifying device capable of identifying a dislodged state where the arterial puncture needle or the venous puncture needle is dislodged from the patient, in accordance with the change in the impedance that is an object of monitoring by the monitoring device.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: October 4, 2022
    Assignee: Nikkiso Company Limited
    Inventors: Hitoshi Goto, Kunihiko Akita, Masahiro Toyoda
  • Patent number: 11419963
    Abstract: A blood purification apparatus with a blood circuit that allows a patient's blood to extracorporeally circulate and a blood purifier connected to the blood circuit and that purifies the blood in extracorporeal circulation are attachable, the blood purification apparatus including a dialysate introduction line through which dialysate is introduced into the blood purifier; a dialysate drain line through which waste dialysate resulting from blood purification performed by the blood purifier is drained from the blood purifier; and a concentration-detecting unit that detects a concentration of a predetermined substance in the waste dialysate flowing through the dialysate drain line.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: August 23, 2022
    Assignee: Nikkiso Company Limited
    Inventors: Satoru Kawarabayashi, Shinya Hasegawa, Tomoya Murakami, Kunihiko Akita, Masahiro Toyoda
  • Patent number: 11413387
    Abstract: There is provided a blood purification apparatus with which the efficiency of dialysate purification can be improved and the reduction in the amount of electrolytes contained in dialysate and necessary for treatment can be suppressed. The blood purification apparatus includes a storage device capable of storing a predetermined amount of dialysate that is necessary for blood purification treatment, a dialysate circulation line through which the dialysate is allowed to circulate by introducing the dialysate in the storage device into the dialyzer and draining waste liquid from the dialyzer into the storage device, and the dialysate purification device that purifies the dialysate in the dialysate circulation line. A treatment state in which the dialysate is allowed to be introduced into the dialyzer without flowing through the dialysate purification device and a purification state in which the dialysate is allowed to be purified by the dialysate purification device are taken switchably.
    Type: Grant
    Filed: March 21, 2019
    Date of Patent: August 16, 2022
    Assignee: Nikkiso Company Limited
    Inventors: Satoru Kawarabayashi, Sumiaki Matsuo
  • Patent number: 11406747
    Abstract: An extracorporeal circulation apparatus including a blood circuit including an arterial blood circuit and a venous blood circuit whose proximal ends are connected to a blood purifier, the blood circuit allowing a patient's blood to extracorporeally circulate from a distal end of the arterial blood circuit to a distal end of the venous blood circuit; a discharge unit through which a priming solution supplied into the blood circuit is discharged to an outside; a negative-pressure-generating unit that generates a negative pressure in a region of the blood circuit, the region being filled with the priming solution; and a control unit that controls the negative-pressure-generating unit.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: August 9, 2022
    Assignee: Nikkiso Company Limited
    Inventors: Shunichi Koda, Shunsuke Kawamura, Shingo Okamoto
  • Patent number: 11333602
    Abstract: A fluid measuring apparatus is provided with: an irradiating device configured to irradiate a fluid with light; a light receiving device configured to receive light scattered by the fluid; a detecting device configured to detect a backflow of the fluid on the basis of a received light signal of the light receiving device; and a calculating device configured to calculate estimated concentration information indicating a concentration of the fluid, on the basis of a detection result of the detecting device and the received light signal of the light receiving device. By this, even if the backflow temporarily occurs in the fluid, the fluid concentration can be accurately measured.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: May 17, 2022
    Assignees: PIONEER CORPORATION, NIKKISO COMPANY LIMITED
    Inventors: Kiyoshi Tateishi, Wataru Onodera, Tomoya Murakami, Akari Agata, Genki Adachi
  • Patent number: 11311251
    Abstract: An exercise support apparatus is capable of supporting exercise taken by a patient during blood purification treatment and includes an estimation generating device that generates an estimation representing a circulating-blood-volume rate of change regarding a circulating blood volume that is estimated to be observed after the exercise is started, the estimation being generated after the blood purification treatment is started and from a continuous measurement of the circulating-blood-volume rate of change as regarding changes in circulating blood volume that is conducted before the exercise is started; a calculating device that calculates a difference between a measured value of the circulating-blood-volume rate of change that is acquired after the exercise during the blood purification treatment is started and a value of the estimation generated by the estimation generating device; and a first monitoring device that monitors whether the difference or ratio calculated by the first calculating device is over a
    Type: Grant
    Filed: May 22, 2019
    Date of Patent: April 26, 2022
    Assignee: Nikkiso Company Limited
    Inventors: Hitoshi Goto, Kunihiko Akita, Nobuhiko Aida
  • Publication number: 20220111134
    Abstract: A blood purification device includes a blood circuit for extracorporeally circulating blood of a patient; a liquid supply circuit for supplying a supply liquid to the blood circuit or to a blood purifier provided on the blood circuit and a waste liquid circuit for discharging the waste liquid from the blood purifier. Each of the blood circuit, the liquid supply circuit and the waste liquid circuit comprises a flexible tube. The blood purification device comprises a tube identification unit that performs a tube identification process for identifying a tube used for the blood circuit, the liquid supply circuit or the waste liquid circuit or determining whether or not there is an abnormality in the tube, based on an amount of liquid sent from a peristaltic pump provided on the blood circuit, the liquid supply circuit or the waste liquid circuit, or pressure fluctuation in the circuit, caused when driving the pump for a predetermined time.
    Type: Application
    Filed: August 29, 2019
    Publication date: April 14, 2022
    Applicant: Nikkiso Company Limited
    Inventors: Tomohiro Furuhashi, Kazuhide Ono, Hideto Maki, Ferenc Kazinczi
  • Patent number: 11278655
    Abstract: A blood purification apparatus in which whether or not the connection of a communicating line is appropriate can be determined more accurately.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: March 22, 2022
    Assignee: Nikkiso Company Limited
    Inventors: Yuta Naruse, Shinya Hasegawa, Wataru Matsushita
  • Patent number: 11209359
    Abstract: A measuring apparatus is provided with: an irradiator configured to irradiate fluid with light; a first light receiver configured to receive a forward scatter component of scattered light scattered by the fluid; a second light receiver configured to receive a backscatter component of the scattered light; a third light receiver configured to receive a side scatter component of the scattered light; and an outputting device configured to output fluid information about the fluid, which is obtained on the basis of light receiving signals of the first light receiver, the second light receiver, and the third light receiver. According to this measuring apparatus, it is possible to output accurate fluid information because of the use of the forward scatter component, the backscatter component, and the side scatter component of the scattered light.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: December 28, 2021
    Assignees: PIONEER CORPORATION, NIKKISO COMPANY LIMITED
    Inventors: Ikuya Kikuchi, Atsuya Ito, Ryohei Kagawa, Tomoya Murakami, Akari Agata, Genki Adachi
  • Patent number: 11179507
    Abstract: A blood purification apparatus to which a blood circuit that allows a patient's blood to extracorporeally circulate and a blood purifier connected to the blood circuit and that purifies the blood in extracorporeal circulation are attachable, the blood purification apparatus including a dialysate introduction line through which dialysate is introduced into the blood purifier; a dialysate drain line through which waste dialysate resulting from blood purification performed by the blood purifier is drained from the blood purifier; and a concentration-detecting unit that detects a concentration of a predetermined substance in the waste dialysate resulting from the blood purification by the blood purifier and flowing through the dialysate drain line.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: November 23, 2021
    Assignee: Nikkiso Company Limited
    Inventors: Satoru Kawarabayashi, Shinya Hasegawa, Tomoya Murakami, Kunihiko Akita, Masahiro Toyoda
  • Patent number: 11123463
    Abstract: A blood purification apparatus in which the error in the amount of discharge from a blood pump that is caused by the change in the suction pressure of the blood pump is reduced. A blood purification apparatus includes a blood circuit through which blood of a patient is extracorporeally circulated; a dialyzer connected to proximal ends of an arterial blood circuit and a venous blood circuit and that purifies the blood extracorporeally circulating through the blood circuit; a squeezable tube connected to the arterial blood circuit; a blood pump allowing liquid in the squeezable tube to flow by squeezing the squeezable tube in a lengthwise direction while compressing the squeezable tube in a radial direction; and a pressure-detecting device attached to a predetermined position of the arterial blood circuit that is nearer to a distal end than a position where the blood pump is provided, the pressure-detecting device being capable of detecting a suction pressure of the blood pump.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: September 21, 2021
    Assignee: Nikkiso Company Limited
    Inventors: Makoto Tokunaga, Kunihiko Akita
  • Patent number: 11090419
    Abstract: Provided is a blood purification apparatus which can continue to accurately monitor a blood purification treatment state even if treatment conditions are changed during blood purification treatment. The blood purification apparatus can perform real-time monitoring on the blood purification treatment state, based on a concentration change in a discharge solution which is obtained by an arithmetic device. The blood purification apparatus includes a treatment condition change device that sets or changes treatment conditions as requested, and that causes a discharge solution concentration sensor to previously detect concentration of the discharge solution under the respective treatment conditions, and a storage device that stores the concentration of the discharge solution under the respective treatment conditions which is detected by the discharge solution concentration sensor in the treatment condition change device, as a first predetermined value corresponding to the respective treatment conditions.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: August 17, 2021
    Assignee: Nikkiso Company Limited
    Inventors: Tomoya Murakami, Kunihiko Akita, Masahiro Toyoda
  • Patent number: 11080119
    Abstract: An information processing device is provided with: a first processing unit that generates first information by performing first processing with respect to sensor information acquired from a sensor; a second processing unit that generates second information by performing, with respect to the first information, second processing that is different from the first processing; and a third processing unit, which generates third information by performing, with respect to the first information, third processing, i.e., processing that corresponds to at least a part of the second processing, and which acquires the second information, and outputs the second information and the third information.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: August 3, 2021
    Assignees: PIONEER CORPORATION, NIKKISO COMPANY LIMITED
    Inventors: Tadashi Kondo, Wataru Onodera, Tomoya Murakami, Akari Agata, Genki Adachi
  • Patent number: 11013903
    Abstract: A clamping device that is always capable of clamping a flexible tube in a good manner and assuredly closing the flexible tube without a large clamping force. A clamping device includes a holding member that holds a flexible tube in which a fluid is allowed to flow, and a clamping member that clamps and closes a clamping portion of the flexible tube that is held by the holding member. The clamping device further includes a heating device that heats the clamping portion of the flexible tube.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: May 25, 2021
    Assignee: Nikkiso Company Limited
    Inventor: Hiroshi Miyaji