Patents Assigned to Nikkiso Company Limited
  • Patent number: 10406273
    Abstract: A blood purification apparatus that is capable of performing a liquid spill prevention operation and uniformizing the amount of air introduced through an opened portion. The blood purification apparatus includes a dialysate introduction line that allows dialysate to be introduced into a dialyzer; a dialysate discharge line that allows the dialysate to be discharged from the dialyzer; coupling tools that allow free switching between a connected state which causes a closed circuit, and an opened state which causes the closed circuit to be opened to form an opened portion; and a control means that performs a liquid spill prevention operation in which external air is introduced through the opened portion. An air detection means, by which air introduced through the opened portion is detectable, is provided in the vicinity of the coupling tools, and the control means stops the liquid spill prevention operation when air is detected by the air detection means.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: September 10, 2019
    Assignee: Nikkiso Company Limited
    Inventors: Wataru Matsushita, Kentaro Kogoshi
  • Patent number: 10398836
    Abstract: A clamping device comprising: a one end portion having a locked part at a tip and an other end portion having a locking part capable of locking the locked part, wherein the one end portion or the other end portion has an interfering part, and when the one end portion is further pressed with the locked part being locked by the locking part, the interfering part interferes with an appropriate part and prevents further movement of the locked part.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: September 3, 2019
    Assignee: Nikkiso Company Limited
    Inventors: Ryo Kato, Shigeaki Funamura
  • Patent number: 10322278
    Abstract: A clamping device is provided in which an other end portion is prevented from being excessively displaced in the transition from a clamped state to an unclamped state. A clamping device includes a one end portion having a locked part at a tip, an other end portion having a locking part capable of locking the locked part, a middle portion continuous with the one end portion and with the other end portion, and an insertion hole (H1, H2) allowing a flexible tube T to be inserted therethrough. An unclamped state is established when the locked part locked is unlocked by bending the other end portion such that the other end portion is displaced from the one end portion. The clamping device is configured to clamp the flexible tube T in a clamped state where a first projection and a second projection are positioned close to each other and to intercept a flow of a fluid at a clamped position.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: June 18, 2019
    Assignee: Nikkiso Company Limited
    Inventors: Ryo Kato, Shigeaki Funamura
  • Patent number: 10315022
    Abstract: An object is to provide a co-injection member which can smoothly collect a liquid of an internal flow route, which can smoothly inject a liquid into the internal flow route, and which can reliably prevent congestion of the liquid in the internal flow route. A co-injection member includes a main body that can be connected to a blood circuit through which blood is circulated, an internal flow route that is formed inside the main body, and that can circulate the liquid of the blood circuit, an inlet flow route that is formed inside the main body, and that introduces the blood into the internal flow route, an outlet flow route that is formed inside the main body, and that can discharge the blood of the internal flow route, and a rubber member that is attached to an opening formed in the main body, and that separates the inside and the outside of the internal flow route from each other.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: June 11, 2019
    Assignee: Nikkiso Company Limited
    Inventors: Shingo Okamoto, Kazuhide Ono, Katsumi Imigi
  • Patent number: 10314961
    Abstract: A dialysate-extracting apparatus is provided in which scattering of dialysate that may occur when an opening-and-closing device is detached from a collecting port can be prevented and the cleanliness of the collecting port can be assuredly maintained. The dialysate-extracting apparatus includes a dialysate-extracting device connected to a dialysate flow route and having a collecting port from which dialysate flowing in the dialysate flow route is collectable, and an opening-and-closing device detachable from and attachable to the dialysate-extracting device in such a manner as to open and close the collecting port and including a seal portion that seals the collecting port in a closed state. When the opening-and-closing device is detached from the dialysate-extracting device, a part of the opening-and-closing device that is on an inner side with respect to the seal portion is bendable and displaceable toward the collecting port.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: June 11, 2019
    Assignee: Nikkiso Company Limited
    Inventors: Fumihiko Ishizaki, Sumiaki Matsuo, Tadashi Iwahori
  • Patent number: 10314957
    Abstract: A blood purification apparatus is provided that can easily and accurately determine before treatment whether or not blocking of liquid by a check valve is appropriate.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: June 11, 2019
    Assignee: Nikkiso Company Limited
    Inventors: Fumihiko Ishizaki, Satoshi Takeuchi
  • Patent number: 10307522
    Abstract: A blood purification apparatus is provided that allows setting work at the time of blood purification treatment or preparation for the treatment to be easily and smoothly performed.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: June 4, 2019
    Assignee: Nikkiso Company Limited
    Inventor: Hiroaki Mochizuki
  • Patent number: 10300191
    Abstract: A blood purification apparatus comprising: a blood circuit including an arterial blood circuit and a venous blood circuit and that is capable of extracorporeally circulating blood of a patient from a distal end of the arterial blood circuit to a distal end of the venous blood circuit; a blood purification device provided between the arterial and the venous blood circuit of the blood circuit and that is capable of purifying the blood flowing in the blood circuit; a dialysate introduction line for introducing dialysate into the blood purification device and a dialysate drain line for discharging drain liquid from the blood purification device; a liquid delivery pump provided to the dialysate introduction line and that is capable of causing the dialysate in the dialysate introduction line to flow; a heating device that is capable of heating the dialysate to be introduced from the dialysate introduction line into the blood purification device; a temperature-detecting device that is capable of detecting a temperat
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: May 28, 2019
    Assignee: Nikkiso Company Limited
    Inventors: Hiroaki Mochizuki, Harutoshi Okabe, Sumiaki Matsuo
  • Patent number: 10220131
    Abstract: The blood purification system includes a plurality of monitoring devices (1) with a dialyzer (5) to perform a blood purification treatment on a patient. A dialysate supplying device (2) supplies a dialysate to each of the monitoring devices (1). The plurality of monitoring devices (1) and the dialysate supplying device (2) are connected to each other by a LAN cable ?. Predetermined information can be transmitted from the dialysate supplying device (2) to a specified monitoring device (1), out of the plurality of monitoring devices (1). The specified monitoring device (1) can perform an individual operation.
    Type: Grant
    Filed: November 30, 2013
    Date of Patent: March 5, 2019
    Assignee: Nikkiso Company Limited
    Inventors: Masaru Kuchiki, Hiroaki Suzuki, Harutoshi Okabe
  • Patent number: 10195336
    Abstract: There are provided a blood purification apparatus and a priming method thereof which can reliably perform air bubble purging of a blood purification device while workability is maintained during priming. During the priming, an air purging step is performed by causing a blood pump to perform reverse rotation, and electromagnetic valves and are brought into an opened state so as to open the overflow line (L) and a priming solution supply line and so as to discharge a priming solution from an overflow line while supplying a dialysate functioning as the priming solution from the priming solution supply line.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: February 5, 2019
    Assignee: NIKKISO COMPANY LIMITED
    Inventors: Kentaro Kogoshi, Satoshi Takeuchi
  • Patent number: 10183106
    Abstract: A blood purification system includes a plurality of monitoring devices (1) each attached to a dialyzer (5) to perform a blood purification treatment on a patient. A dialysate supplying device (2) supplies a dialysate to each of the monitoring devices (1). The plurality of monitoring devices (1) and the dialysate supplying device (2) are connected to each other by a LAN cable ?. Thus, predetermined individual information relating to the plurality of monitoring devices (1) is transmitted from each of the monitoring devices (1) to the dialysate supplying device (2).
    Type: Grant
    Filed: November 30, 2013
    Date of Patent: January 22, 2019
    Assignee: Nikkiso Company Limited
    Inventors: Harutoshi Okabe, Hiroaki Suzuki, Masaru Kuchiki
  • Patent number: 10124106
    Abstract: The blood purification apparatus has a control device (19) that performs a venous returning blood process S1, an arterial returning blood process S4 and a negative pressure applying process S1a. The returning of the blood is performed by substituting a physiological saline solution for the blood in the blood circuit. The negative pressure applying process S1a releases a negative pressure after applying the negative pressure to a flow route on an upstream side from an arrangement position of a blood pump 4 in the arterial blood circuit (1). The blood pump (4) is in a normal rotation and an electromagnetic valve V3 switches over the physiological saline solution supplying line 8 from a closing state to a circulating state.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: November 13, 2018
    Assignee: Nikkiso Company Limited
    Inventors: Hiroshi Nimura, Kazumi Yokoyama, Tomohiro Furuhashi
  • Patent number: 10046104
    Abstract: A peristaltic pump includes a mounting concave section 8a on which a peristaltically-actuated tube connected to an arterial blood circuit is mountable; a roller which compresses the peristaltically-actuated tube mounted on the mounting concave section in a radial direction and causes the peristaltically-actuated tube to be peristaltically actuated in a longitudinal direction such that a liquid therein is flowable in the arterial blood circuit; a load sensor that is able to detect displacement of the peristaltically-actuated tube 1a mounted on the mounting concave section in the radial direction; and blockage detecting means that is able to detect a blockage of the arterial blood circuit based on the displacement detected by the load sensor.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: August 14, 2018
    Assignee: NIKKISO COMPANY LIMITED
    Inventors: Sumiaki Matsuo, Kunihiko Akita
  • Patent number: 9951766
    Abstract: A pressure detection device of a liquid flow route includes; displacement detecting means that detects displacement of a peristaltically-actuated tube in the radial direction; pressure calculating means that is able to calculate blood removal pressure based on the displacement of the peristaltically-actuated tube; closed flow route forming means that is able to form a closed flow route which includes a portion at which the displacement detecting means is disposed; pressure changing means that is able to arbitrarily change the pressure in the closed flow route; pressure detection means that is able to detect pressure change in the closed flow route; and calibration curve acquiring means that is able to produce and acquire a calibration curve with which the displacement detecting means and the pressure calculating means are calibrated by a relationship between the pressure change detected by the pressure detection means and a detection value of the displacement detecting means.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: April 24, 2018
    Assignee: NIKKISO COMPANY LIMITED
    Inventors: Kunihiko Akita, Sumiaki Matsuo
  • Patent number: 9925119
    Abstract: A dialysate extraction device comprising a dialysate extraction means including an inlet port and an outlet port adapted to be connected to a flow path of fluid for flowing the fluid therethrough and a projected collection port for collecting the fluid flowing through the inlet and outlet port; a outer circumference wall part mounted on the dialysate extraction means so that it covers a projected end of the collection port and is projected therefrom; a connection member formed with a connection portion to be connected to the collection port and a fitting portion to be fitted into an inner circumference of the outer circumference wall part and adapted to extract the fluid through the collection port under a condition in which the connection portion is connected to the outer circumference wall part; and correction portions formed on the inner circumference of the outer circumference wall part for correcting position and attitude of the connection member relative to the collection port before a tip end of the co
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: March 27, 2018
    Assignee: NIKKISO COMPANY LIMITED
    Inventors: Masahiro Takahashi, Yusuke Nakano, Fumihiko Ishizaki, Hachiro Edamura, Hiroshi Nimura
  • Patent number: 9885348
    Abstract: A reciprocation pump has a supply liquid-side sub-pumping chamber arranged adjacent to the supply liquid-side pumping chamber at an external side. A waste liquid-side sub-pumping chamber is arranged adjacent to the waste liquid-side pumping chamber at an external side. A rod extends through the supply liquid-side sub-pumping chamber, the supply liquid-side pumping chamber, the waste liquid-side pumping chamber and the waste liquid-side sub-pumping chamber. The rod is connected to the reciprocation mechanism and the driving source to transmit a driving force of the driving source to the reciprocation mechanism. Sealing members are arranged, respectively, in walls through which the rod extends to partition the supply liquid-side pumping chamber and the supply liquid-side sub-pumping chamber as well as the waste liquid-side pumping chamber and the waste liquid-side sub-pumping chamber.
    Type: Grant
    Filed: May 24, 2012
    Date of Patent: February 6, 2018
    Assignee: Nikkiso Company Limited
    Inventor: Hiroaki Suzuki
  • Patent number: 9878083
    Abstract: A blood purification apparatus which can perform actions and operations according to the final stage of blood-return.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: January 30, 2018
    Assignee: NIKKISO COMPANY LIMITED
    Inventors: Tomohiro Furuhashi, Satoshi Takeuchi, Akira Sugioka, Masahiro Toyoda
  • Patent number: 9872951
    Abstract: The present teachings provide a blood purification apparatus and a priming method, which can reduce or dispense with dedicated components used for automated priming and which can reduce manufacturing costs of a blood circuit while achieving the automated priming. The present teachings further provide a blood purification apparatus including a liquid level adjustment device that can optionally introduce or discharge air into or from an upper portion of a venous air trap chamber, a control device that can adjust a liquid level formed inside the venous air trap chamber to have the height at any desired position by operating the liquid level adjustment device, and a priming solution supplying line that can supply a priming solution to an arterial blood circuit and a venous blood circuit.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: January 23, 2018
    Assignee: NIKKISO COMPANY LIMITED
    Inventors: Tomohiro Furuhashi, Satoshi Takeuchi, Akira Sugioka, Masahiro Toyoda
  • Patent number: 9662433
    Abstract: A pressure detection device of a liquid flow route is provided which detects a pressure of an arterial blood circuit consisting of a flexible tube, a portion of which is connected to a peristaltically-actuated tube that can cause an internal liquid to flow by being compressed in a radial direction and being peristaltically actuated in a longitudinal direction in a roller of a blood pump, and which enables a predetermined liquid to be circulated. The pressure detection device includes a load sensor that detects radial displacement of the peristaltically-actuated tube.
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: May 30, 2017
    Assignee: NIKKISO COMPANY LIMITED
    Inventors: Sumiaki Matsuo, Kazumi Yokoyama, Kunihiko Akita
  • Patent number: 9623166
    Abstract: A mixing apparatus which can reliably prevent an auxiliary liquid from being unintentionally mixed into a main unit even when a failure occurs in a switching device, and which can prevent the switching device or an auxiliary flow route from being damaged even when a pressurizing device malfunctions due to the failure. The mixing apparatus includes a pipe circulating dilution water; a pipe circulating a disinfecting solution; a pressurizing pump circulating the disinfecting solution in the pipe toward the pipe; and a check valve capable of optionally turning on and off the pipe.
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: April 18, 2017
    Assignee: NIKKISO COMPANY LIMITED
    Inventors: Hiroaki Mochizuki, Harutoshi Okabe