Abstract: Exemplary embodiments of the present disclosure include apparatus and methods to identify endometrial tissue.

Abstract: Provided herein are chimeric polypeptides that may be used, e.g., for the diagnosis of or vaccination against Ehrlichia chaffeensis and/or Ehrlichia canis.

Abstract: Exemplary embodiments of the present disclosure include apparatus and methods to classify the plaque tissue present in the coronary artery using intravascular optical coherence tomography (IVOCT) images.

Abstract: A system and method to measure blood oxygenation levels and total hemoglobin on individually selected blood vessels, to provide a representation of the subject condition and of tissue perfusion that may be used for diagnosing specific tissue conditions. Reflection spectra from individual blood vessels or a collection of vessels are measured by using wide-field imaging for selecting target vessels and a narrow-field confocal detection system to enable measuring local blood oxygenation and hemoglobin. Optical fibers may be used to illuminate the target vessel and to detect light diffusively reflected therefrom. The reflection spectra may be analyzed in a spectrometer to extract the ratio of the deoxy- to oxyhemoglobin and to determine their absolute concentration for computing total hemoglobin levels. An alternative implementation uses image processing on camera images of a blood vessel, generated at an isosbestic wavelength of the deoxy- and oxyhemoglobin, and optionally also at neighboring wavelengths.

Abstract: Disclosed is a closed drift, narrow channel Hall thruster configured to operate at powers <30 W. The thruster includes a thruster body and a neutralizing cathode. The thruster body includes a magnetic circuit including a magnetic source and two magnetic poles, a metallic, annular thruster channel formed by the magnetic poles with a downstream channel width smaller than about 3 mm and an upstream channel width greater than the downstream channel width, an anode positioned at the channel's entry, and a gas distributor configured to release a propellant gas into the thruster channel. The magnetic circuit is configured to generate a magnetic field in the thruster channel for trapping electrons therein. The channel walls (the magnetic poles) are under bias potential. The anode and the cathode are configured to generate a substantially axial electric field in the thruster channel.

Abstract: A composition comprising a carbon material comprising a first channel with a width in the range of 50 nm to 1000 nm and a second channel with a width in the range of 20 nm to 200 nm, wherein the second channel comprises branches and is in fluid communication with the first channel, is provided. Further, articles comprising the composition are provided. A method for making a templated carbon material with hierarchical porosity is also provided.

Abstract: Provided herein is a porous PLA-based monolith having a microstructure templated by an external phase of a HIPE, as well as processes of manufacturing the same and uses thereof.

Abstract: Provided is a system for continuous generation of gases, the system including an electrochemical device and an active- material regeneration device.

Abstract: A monolithic solid state system comprises a ferroelectric crystal and a semiconductor crystal arranged laterally to define a nanolayer having a heterojunction between the two crystals. In some embodiments, the ferroelectric crystal exhibits in-plane polarization.

Abstract: The present invention provides methods for determining malignancy in a cyst by measuring viscosity of cyst fluid while under stain. The invention further provides devices, and computer program products for determining same.

Abstract: The present invention provides a flow-gate design that utilizes chemo-responsive colloidal particles to control the flow rate therethrough. The flow-gate operates by changing the compactness of the colloidal particles, which changes in response to changes in pH or ionic strength in the flow medium or the surrounding environment. The design also allows the flow-gate as a size-discriminating filter. The ability to control the flow rate in response to changes in the flow medium or the environment makes the presently provided flow-gate useful for a variety of applications, including those that require automatic control of the flow rate, and automatic irrigation.

Abstract: Anion exchange membrane electrode assemblies, fuel cells and electrochemical cells comprising such assemblies, which comprise an anion exchange membrane sandwiched between an anode compartment and a cathode compartment, and which are operable at a temperature of at least 100° C., are provided. Systems, devices, articles and methods that utilize such assemblies at an operating temperature of at least 100° C. are also provided.

Abstract: The present invention relates to an heparanase-binding and heparanase-neutralizing monoclonal antibody (IgG-1 mAb A54), including its epitope (HBD-II) and mode of interaction with heparanase, pharmaceutical composition comprising same, and uses thereof e.g. for inhibiting or treating a disease or disorder associated with heparanase activity, including but not limited to cancer, inflammation, viral infection, diabetes and related complications. The present invention further provides combinatorial cancer therapies, comprising the heparanase-neutralizing mAb and an additional anti-cancer treatment such as chemotherapy or radiation.

Abstract: Provided herein are methods and compositions for a suicide gene approach comprising an expression vector comprising a cell cycle-dependent promoter driving the expression of a suicide gene. Also provided herein are methods to render proliferative cells sensitive to a prodrug after transplantation but avoids expression of the suicide gene in post-mitotic cells, such as neurons.

Abstract: In some aspects, methods and probiotic compositions are provided for the treatment of bone diseases such as, e.g., ostetoporosis. In some embodiments, one or more bacteria from the warm microbiota such as, e.g., Clostridialeace-assimilate, Lactobacillus, Bifidobacteriaceae, Akkermansia, and/or Parabacteroides may be administered to a subject, such as a human subject, to treat the bone disease. In some embodiments, heat may be applied to the subject to promote the development of warm microbiota to treat the bone disease.

Abstract: The present invention is directed to a method for treating a bowel disease in a subject in need thereof, the method comprising inhibiting the activity of neurons of the insular cortex of the subject. Further provided is a system comprising a transcranial stimulation transducing coil for transcranial stimulation configured to provide a series of pulses to neurons of the insular cortex.

Abstract: An analog to digital converter comprises an input for receiving an analog input signal; a plurality of outputs for outputting parallel bits of a digital signal that represents said analog input signal; and a neural network layer providing connections between each of said outputs respectively, each connection having an adjustable weighting. The synapses of the neural networks may be memristors and training may use online gradient descent.

Abstract: Provided is a superabsorbent structure based on a covalently crosslinked copolymer having a microstructure of a HIPE, and characterized by hydrophobic and hydrophilic segments of at least five residues; the unique chemical and structural properties of the copolymer afford a polymeric superabsorbent structure that is capable of swelling in polar as well as apolar media. Also provided are processes of manufacturing the superabsorbent structure, and uses thereof.

Abstract: A method of fabricating an optical element, comprises fabricating a three-dimensional mold having a relief pattern complementary to a pattern of the optical element to be fabricated, contacting the relief pattern with a solidifiable transmissive material, and solidifying the material thereby forming a transmissive substrate having the pattern thereupon. The method also comprises contacting the transmissive substrate with one or more substances wherein a difference in refractive indices between the substance(s) and the transmissive substrate is less than about 0.1.

Abstract: Methods and compositions for diagnosing and vaccinating against Ehrlichia canis and Ehrlichia chaffeensis are provided.