Patents Assigned to Siemens Healthcare Diagnostics Products GmbH
  • Patent number: 11951469
    Abstract: A device for storing reagent containers on several planes for an automatic analysis appliance comprises a pipetting device comprising a pipetting needle for pipetting of reagents, a first device comprising a plurality of first receiving positions for reagent containers, wherein the first receiving positions are arranged on a first plane, and a second device comprising a plurality of second receiving positions for reagent containers, wherein the second receiving positions are arranged on a second plane.
    Type: Grant
    Filed: June 4, 2020
    Date of Patent: April 9, 2024
    Assignee: Siemens Healthcare Diagnostic Products GmbH
    Inventor: Thorsten Michels
  • Patent number: 11953503
    Abstract: Provided is a universal method for quantitatively determining therapeutic tumor necrosis factor (TNF)-alpha inhibitors in patient samples that is sufficiently sensitive for being able to detect all therapeutic TNF-alpha inhibitors.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: April 9, 2024
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Harald Althaus, Thorsten Keller
  • Publication number: 20230374564
    Abstract: A method and kit are provided herein for determining the ADAMTS-13 activity in a sample. The method comprises contacting the sample with a von Willebrand factor (VWF) polypeptide which has been coupled to a reporter enzyme, such as glucose-6-phosphate dehydrogenase (G6PDH).
    Type: Application
    Filed: May 15, 2023
    Publication date: November 23, 2023
    Applicant: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Herbert SCHWARZ, Frank VITZTHUM
  • Patent number: 11774461
    Abstract: The present invention pertains to the field of coagulation diagnostics and relates to a prothrombin time reagent on the basis of recombinant or native tissue factor protein and phospholipids, which reagent can be stabilized by the addition of an iron chelator from the groups of siderophores and 3,5-diphenyl-1,2,4-triazoles.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: October 3, 2023
    Assignee: Siemens Healthcare Diagnostics Products GMBH
    Inventors: Sabine Pilgrim, Thomas Wissel, Norbert Zander
  • Publication number: 20230280359
    Abstract: Embodiments of the present invention are in the field of blood coagulation diagnostics and relate to a test for establishing an individual's blood coagulation system status based on the amount of in-vitro-generated F1+2 peptide, and to a test kit for use in such a method.
    Type: Application
    Filed: March 2, 2023
    Publication date: September 7, 2023
    Applicant: Siemens Healthcare Diagnostics Products GmbH
    Inventor: Juergen PATZKE
  • Patent number: 11567097
    Abstract: The invention relates to an apparatus for optically monitoring the dosing of a liquid to be pipetted for an automatic analysis unit. The apparatus comprises a dosing device, comprising a pipetting needle for pipetting the liquid, a lighting device for illuminating a drop of the liquid adhering to the pipetting needle, a camera with a set of optics to capture an image of the drop of the liquid, and an evaluation device for characterizing the drop of liquid by means of an automatic analysis of the image of the drop of liquid.
    Type: Grant
    Filed: June 11, 2020
    Date of Patent: January 31, 2023
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Dominik Andreas Daume, Thorsten Michels
  • Patent number: 11426737
    Abstract: A waste disposal system for the disposal of consumables through a waste chute into a waste container includes a waste chute having a first opening and a second opening, wherein the first opening is situated outside the waste container and the second opening opens toward the waste container. The first opening and the second opening are arranged at a first distance from one another, wherein the waste chute includes a plurality of self-resetting lamellae for the partial or complete closure of the openings. The lamellae form at least two lamella annuli arranged at a second distance above one another, wherein at least one first lamella annulus closes the first opening and at least one second lamella annulus closes the second opening, and the second distance between the lamella annuli is at least one third, preferably at least half and particularly preferably at least three quarters of the first distance.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: August 30, 2022
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Heiko Kalbfell, Joachim Bernhard
  • Patent number: 11320439
    Abstract: The present disclosure is in the field of in vitro diagnostics and relates to an easily automatable binding assay for establishing a heparin-induced thrombocytopenia, which binding assay uses Fc?RIIa protein-coated particles.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: May 3, 2022
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Harald Althaus, Herbert Schwarz, Norbert Zander
  • Patent number: 11262357
    Abstract: The present invention relates to a functional, easily automatable assay for establishing a heparin-induced thrombocytopenia (HIT). What is measured is the secretion of PF4 (platelet factor 4) from activated thrombocytes.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: March 1, 2022
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Harald Althaus, Gerlinde Christ, Herbert Schwarz, Michaela Wicke, Norbert Zander
  • Patent number: 11072717
    Abstract: In the field of consumable materials for automatic analytical instruments, transparent plastic cuvettes having increased scratch resistance and a method for producing same includes contacting exclusively an outer surface of the transparent plastic cuvette with a liquid comprising at least one surfactant or with a triglyceride and subsequently drying the outer surface such that scattered-light optical properties of the transparent plastic are not adversely affected.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: July 27, 2021
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Josef Meindl, Oksana Pryshchepna
  • Patent number: 10822636
    Abstract: The invention relates to the field of blood clotting diagnosis and relates to a kinetic method for determining the fibrinogen concentration in a human plasma sample according to the Clauss method.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: November 3, 2020
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Dirk Greis, Norbert Zander
  • Patent number: 10788505
    Abstract: A measuring system for measuring a sample in an automated analysis machine comprises a measuring device for recording measurement values of a measured variable and a first controller and a second controller for processing the measurement values and a sliding contact system with sliding contacts, wherein the measurement values are transferred from the measuring device to the first controller and wherein the measurement values are transferred from the first controller to the second controller via the sliding contacts. The measuring system comprises an error counter which captures the errors occurring during the transfer of the measurement values from the first controller to the second controller via the sliding contacts.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: September 29, 2020
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Wolfgang Steinebach, Christian Verhalen
  • Patent number: 10739363
    Abstract: The present invention lies in the field of automated analyzers and relates to a method for mixing liquids in liquid containers. The arrangement for automated mixing comprises a shaking device and a gripper which is connected by way of a flexible connecting element to a transfer arm and which serves for receiving a liquid container. The coupling of gripper and shaking device is realized by way of an eccentrically movable coupling pin and a coupling hole provided for this purpose.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: August 11, 2020
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Joachim Bernhard, Christian Verhalen
  • Patent number: 10591490
    Abstract: Described herein are method(s), kit(s), reagent(s) and the like for determining von Willebrand factor (VWF) activity in a sample in the absence of ristocetin.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: March 17, 2020
    Assignee: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH
    Inventors: Harald Althaus, Tobias Obser, Juergen Patzke, Reinhard Schneppenheim
  • Patent number: 10514387
    Abstract: The present invention lies in the field of automated analysis devices and relates to a method for monitoring the functionality of a wash station (1) for pipetting needles (2).
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: December 24, 2019
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Ayoub Bouteffah-Touiki, Thorsten Michels
  • Patent number: 10466263
    Abstract: The invention is in the field of automatic analysis devices and relates to a heatable pipetting device for an automatic analysis device and a method for providing a reaction mixture. The pipetting device comprises a pipetting needle having two temperature sensors at different distances to the tip of the pipetting needle.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: November 5, 2019
    Assignee: Siemens Healthcare Diagnostics Products Gmbh
    Inventor: Christian Verhalen
  • Patent number: 10442939
    Abstract: In the field of consumable materials for automatic analytical instruments, a method for producing transparent plastic cuvettes with increased scratch resistance includes contacting exclusively an outer surface of the transparent plastic cuvette with a liquid comprising at least one surfactant or with a triglyceride and subsequently drying the outer surface such that scattered-light optical properties of the transparent plastic are not adversely affected.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: October 15, 2019
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Josef Meindl, Oksana Pryshchepna
  • Patent number: 10401275
    Abstract: The invention relates to an analysis method for supporting classification, a determination method for determining analysis parameters Ys, Ei, Ii, ?i for the analysis method, a computer program product, and an optical analysis system for supporting classification, with which system analysis parameters Ys, Ei, Ii, ?i can be defined on the basis of first and second calibration data. The parameters provide classification support according to the discriminant analysis and on the basis of measured values Pi of optical characteristics i, in particular of organic dispersions, and the information content thereof for classification, in particular the diagnosis of disease; and permit a classification proposal or a diagnosis proposal in comparison with a threshold Ys.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: September 3, 2019
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Barbara Kavsek, Peter Lederer, Peter Taal, Jan van den Boogaart
  • Patent number: 10365291
    Abstract: The present invention is in the field of automated analyzers and relates to a method for transferring a liquid volume in an analyzer. This involves the tip of a pipetting needle touching a wall of a tilted reaction vessel during the dispensing of liquid.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: July 30, 2019
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventor: Thorsten Michels
  • Patent number: 10359438
    Abstract: The present invention lies in the field of automated analyzers and relates to an automated warning system for potentially erroneous measurement results, which may be caused by the loss of a liquid container during a transport process.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: July 23, 2019
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Daniel Heppner, David Solbach, Christian Verhalen