Abstract: The invention relates to a reagent station (1) for an automated analysis device, comprising a first and a second reagent container storage (2, 10) and a transfer apparatus (20) which transfers reagent containers (16) between the first and the second reagent container storage (2, 10). Furthermore, the invention relates to a method for loading an automated analysis device with reagent containers.

Abstract: A method for adjusting a transfer apparatus fastened to a robotically displaceable transfer arm and comprising a holder for a liquid vessel in an automated analysis machine, by way of measuring a first and second force effect on the holder with the aid of a sensor, wherein, if the measured force effects do not deviate from one another by more than a predetermined amount, the transfer apparatus is sufficiently adjusted in respect of a receiving position, and wherein, if the measured force effects deviate from one another by more than a predetermined amount, an adjustment of the transfer apparatus in respect of the receiving position is carried out.

Abstract: The present invention is in the field of coagulation diagnostics and relates to methods for detecting modulators of GPIb-thrombin interaction in a sample. To this end, the sample is contacted with isolated mutated GPIb? protein and thrombin, and the formation of a complex between mutated GPIb? protein and thrombin is determined.

Abstract: The present invention relates to a method for determining the position of a multiplicity of measurement locations in a measurement system of an automated analysis device, and a corresponding automated analysis device with an integrated circuit, which is configured as phase locked loop.

Abstract: The invention relates to a metering pump, for example, for a pipetting apparatus in an automated analysis machine, and to a method for checking the functionality thereof.

Abstract: The invention relates to a device and a method for the transfer of a liquid container with the aid of a clamping gripper in an automated analyzer. For this purpose, the clamping gripper has a controllable expansion device.

Abstract: The invention relates to a pipetting apparatus for an automatic analysis device, which is particularly stable and allows simple and error-proof replacement of the pipetting apparatus and, therefore, particularly reliable operation of the analysis device. To this end, an essentially frustoconical fastening body is arranged around an axial region of the needle body.

Abstract: The invention relates to a hollow needle (1) for a sample pipettor in an automated analysis instrument, which sample pipettor is suitable for withdrawing sample liquid from a sealed sample vessel by virtue of the cover or the cap of the sample vessel being pierced by the hollow needle (1). The hollow needle (1) has a substantially straight cylindrical basic shape with a tip (8) for piercing a cover and enables a removal of sample liquid, comparatively less susceptible to errors, from a sample vessel in an automated analysis instrument. In the region of the tip (8) of the hollow needle (1), a number of faces (22, 26, 28, 30) have been introduced in such a way that the radial force components resulting at the respective faces (22, 26, 28, 30) during an axial movement into an elastic material cancel one another.

Abstract: ABSTRACT The present invention lies in the field of automated analysis apparatuses and relates to a method for transferring a liquid volume from a first liquid vessel into a second liquid vessel. The method ensures increased pipetting accuracy, even from liquid vessels which have foam on the surface of the liquid.

Abstract: Described herein are method(s), kit(s), reagent(s) and the like for determining von Willebrand factor (VWF) activity in a sample in the absence of ristocetin.

Abstract: The present invention relates to a method for optically determining at least one analyte in a sample, in which a deviation from a reference value or the reference curve is evaluated as an indication that the optical determination of the at least one analyte is corrupted by measurement artifacts.

Abstract: Described herein are method(s), kit(s), reagent(s) and the like for determining von Willebrand factor (VWF) activity in a sample in the absence of ristocetin.

Abstract: The invention relates to a method for detecting contact of a pipetting needle in an in vitro diagnostic system. To this end, the pipetting needle, in an advantageous embodiment of the invention, should be cyclically charged by an electric voltage or current applied between the pipetting needle and a reference potential and discharged again by a subsequent electric connection between the pipetting needle and the reference potential. A characteristic variable for the current capacitance between the pipetting needle and the reference potential should be established from a number of measured values detected during the charging and/or discharging. A temporal curve of the characteristic variable should be monitored continuously based on a number of predetermined criteria and a contact signal should be generated if the predetermined criteria are satisfied.

Abstract: The invention relates to a pipetting device for automatic analysis instruments and a method for heating a volume of liquid in a heated pipetting needle.

Abstract: An incubation device for an automatic analysis apparatus includes an incubation unit having a number of reception positions for reaction vessels, a first transfer arm having a gripping device for one or more reaction vessels, which is configured to move the gripping device into a first access region, a second transfer arm having a gripping device for one or more reaction vessels, which is configured to move the gripping device into a second access position. This allows a larger sample throughput of the automatic analysis apparatus with, at the same time, frictionless and reliable operation. To this end, the first and the second access regions do not overlap, and the incubation unit is mounted so that it can be moved in such a way that at least one of the reception positions reaches the first and the second access regions.

Abstract: The invention relates to a pipetting device (1) for an automatic analysis appliance, wherein the pipetting device (1) comprises a pipetting needle (2) with a longitudinal axis (3), and a device (4) for moving the pipetting needle (2). The pipetting device (1) further comprises a holder (5) for the pipetting needle (2), which holder (5) is mounted on the movable device (4) and to which holder the pipetting needle (2) is releasably connected, and a vibration generator which can set at least the tip of the pipetting needle (2) in vibration, wherein the vibration generator is mounted on the movable device (4).

Abstract: The invention relates to a screening process for determining a disordered von Willebrand factor (VWF)-GPIb interaction in a patient's sample. This comprises contacting the sample with isolated GPIb.alpha. protein, with VWF protein and with a solid phase associated with an antibody specific for said isolated GPIb.alpha. protein, and determining complex formation.

Abstract: The invention lies in the area of platelet function diagnostics and relates to a method for the determination of platelet function under flow conditions as well as a device for the implementation of this method. The method is particularly suitable for the determination of the effect of clopidogrel and of other P2Y(12) antagonists with antithrombotic activity as well as the determination of P2Y(1) antagonists with antithrombotic activity.

Abstract: The invention relates to apparatus for determining the position of an automatically displaceable gauge. The apparatus comprises the gauge, a first device for displacing the gauge in the spatial X-direction, a second device for displacing the gauge in a spatial Z-direction, a sensor for identifying the abutment of the gauge on, or the approach thereof to, an article, an at least partly bordered receptacle position, into which the gauge is at least partly insertable by displacing the gauge in the spatial X- and/or Z-direction, and a movable assembly, wherein the receptacle position for the gauge is arranged on the movable assembly.