Patents Assigned to The Governing Council of the University of Toronto
  • Semiconductor nanocrystal particle and production methods thereof
    Patent number: 11312904
    Abstract: A semiconductor nanocrystal particle represented by Chemical Formula 1 and having a full width at half maximum (FWHM) of less than or equal to about 30 nanometers (nm) in the emission wavelength spectrum is provided: AxA?(3+??x)D(2+?)E(9+?).??Chemical Formula 1 In Chemical Formula 1, A is a first metal including Rb, Cs, or a combination thereof, A? is an organic substance derived from an ammonium salt, an organic material derived from an organic ligand, or an organic material including a combination thereof, D is a second metal including Sb, Bi, or a combination thereof E is Cl, Br, I, or a combination thereof, 1<x?3, ?1<?<1, 3+??x>0, ?1<?<1, and ?1<?<1.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: April 26, 2022
    Assignees: SAMSUNG ELECTRONICS CO., LTD., THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Jihyun Min, Eun Joo Jang, Edward H. Sargent, Hyo Sook Jang, Makhsud I. Saidaminov, Sjoerd Hoogland, Ankit Jain, Andrew Johnston, Oleksandr Voznyy
  • Boronic esters and methods for making the same
    Patent number: 11312731
    Abstract: There is provide herein a compound of Formula (1): wherein R1, R2, R3, R4, and R5 are each independently H or an organic group.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: April 26, 2022
    Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Andrei K. Yudin, Aleksandra Holownia
  • Contact passivation for perovskite optoelectronics
    Patent number: 11309138
    Abstract: Disclosed herein are perovskite based optoelectronic devices made entirely via solution-processing at low temperatures (<150° C.) which provide for simple manufacturing, compatibility with flexible substrates, and perovskite-based tandem devices. These perovskite based optoelectronic devices are produced using an electron transport layer on which the perovskite layer is formed which is passivated using a ligand selected to reduce electron-hole recombination at the interface between the electron transport layer and the perovskite layer.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: April 19, 2022
    Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Hairen Tan, Xinzheng Lan, Zhenyu Yang, Sjoerd Hoogland, Edward Sargent
  • Compositions and methods for detecting and treating insulin resistance
    Patent number: 11299735
    Abstract: A miR-1983 inhibitor comprising an anti-miR-1983 oligonucleotide that is complementary to at least part of CTCACCTGGAGCATGTTTTCT (SEQ ID NO: 1), the part comprising at least nucleotides 2 to 8 of CTCACCTGGAGCATGTTTTCT (SEQ ID NO: 1).
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: April 12, 2022
    Assignee: The Governing Council of the University of Toronto
    Inventors: Denise Belsham, Jennifer Chalmers
  • Hemoglobin based oxygen carrier and method of preparation
    Patent number: 11298407
    Abstract: The disclosure concerns a class of hemoglobin based oxygen carriers (HBOCs) comprising a first hemoglobin protein cross-linked by a chemical reaction that is followed by a strain-promoted alkyne-azide cycloaddition (SPAAC) reaction or by a strain-promoted alkyne-nitrone cycloaddition (SPANC) in the absence of added copper salts to a second modified cross-linked hemoglobin protein. The resulting construct is an HBOC that is capable of binding oxygen and releasing same in a useful manner upon addition in an appropriate solution to the circulatory system of a patient. The disclosure also concerns a method of production of the HBOC where a first and second hemoglobin protein are produced by covalently linking hemoglobin to an angle strained cycloalkyne moiety.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: April 12, 2022
    Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Ronald Henry Kluger, Serena Singh, Ina Dubinsky-Davidchik
  • Surfactant additives for digital microfluidic devices for high protein content droplets transport
    Patent number: 11292002
    Abstract: Disclosed herein is a surfactant additive, ethylenediamine tetrakis(ethoxylate-block-propoxylate) tetrol with 16 ethylene oxide repeat units and 18 propylene oxide repeat units (known by its trade name as Tetronic 90R4) used as a droplet-additive, or to coat DMF driving electrode surfaces which dramatically improves the capability to work with high-protein-content liquids (e.g., whole blood) on digital microfluidic chips. This surfactant prevents protein adsorption and fouling of DMF electrode surfaces to an extent that was heretofore impossible. Specifically, this surfactant allows for the manipulation of droplets of undiluted whole blood for >1 hour per electrode (>1 50 times better than what is possible for any known additive). This improvement in handling high protein content media will revolutionize blood-based diagnostics on digital microfluidic platforms.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: April 5, 2022
    Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Ryan Fobel, Alphonsus Hon-Chung Ng, Aaron Ray Wheeler, Man Ho Stephen Ho
  • Mobile device for grasping and active release of objects
    Patent number: 11285599
    Abstract: A three-dimensional (3D) untethered mobile actuator having the following parts: (a) a substrate having two or more magnetized panels, and (b) a frame that connects the magnetized panels, the magnetized panels being made of a polymer with embedded permanent magnetic particles, each magnetized panel of the 3D untethered mobile actuator having a magnetic moment in a different direction than a next neighboring panel, and the 3D untethered mobile actuator having a structural configuration that changes between a substantially flat structural configuration in the absence of a magnetic field, and an actuated structural configuration when under influence of a magnetic field. Methods of manufacturing and using the 3D mobile actuator and a system that includes the 3D mobile actuator are provided.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: March 29, 2022
    Assignee: The Governing Council of the University of Toronto
    Inventors: Eric Diller, Jiachen Zhang
  • Multi-port converter structure for DC/DC power conversion
    Patent number: 11289906
    Abstract: A module for interconnecting a pair of DC sources or a pair of DC loads into a DC bus includes: a first port for each source or load; a switching cell for each first port, each cell having a pair of terminals and a switching node; a second port operatively connected to the DC bus and having a pair of terminals, one of the pair of terminals of the second port being connected to one of the terminals of one of the cells and the other of the pair of terminals of the second port being connected to one of the terminals of the other of the cells; and a filter inductor connected between the switching nodes of the cells. Systems including the module and methods utilizing the system are also disclosed.
    Type: Grant
    Filed: August 15, 2020
    Date of Patent: March 29, 2022
    Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Peter Waldemar Lehn, Mike Kavian Ranjram, Sebastian Rivera Iunnissi, Yuanzheng Han
  • Systems and methods for sustainability and social interaction analysis in building information modeling
    Patent number: 11270036
    Abstract: Described herein are systems and methods for building information modeling. An embodiment of the method includes: receiving a BIM; and transforming the BIM to flatten solid-volume geometry for space bounding elements into thin-walled boundaries of the thermal zones by: determining wall volumes from the BIM; collapsing the wall volumes to provide single surface walls; determining wall center surfaces and end points from the single surface walls; aligning, and trimming or extending, the single surface walls using the wall end points to create closed spaces; connecting the closed spaces vertically to generate a single water tight volume for the closed spaces; and creating interfaces between the single water tight volume for the closed spaces to generate thermal zones.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: March 8, 2022
    Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Tamar El-Diraby, Emmanouil Papangelis, Thomas Krijnen
  • Core/shell-vacancy engineering (CSVE) of catalysts for electrochemical COreduction
    Patent number: 11268199
    Abstract: The invention relates to a catalyst system for electrocatalyzing conversion of CO2 into multi-carbon hydrocarbons and/or alcohols, and to the method to produce it. The catalyst comprises a core-shell structure comprising a core that is composed of metal sulphide and a shell that is composed of a metal with vacancies.
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: March 8, 2022
    Assignees: TOTAL SE, THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Edward Sargent, Tao-Tao Zhuang, Zhi-Qin Liang, Alexander Ip
  • SEMANTIC INPUT SAMPLING FOR EXPLANATION (SISE) OF CONVOLUTIONAL NEURAL NETWORKS
    Publication number: 20220058431
    Abstract: Embodiments of the present disclosure relate to generating explanation maps for explaining convolutional neural networks through attribution-based input sampling and block-wise feature aggregation. An example of a disclosed method for generating an explanation map for a convolutional neural network (CNN) includes obtaining an input image resulting in an output determination of the CNN, selecting a plurality of feature maps extracted from a plurality of pooling layers of the CNN, generating a plurality of attribution masks based on the plurality of feature maps, applying the generated attribution masks to the input image to obtain a plurality of visualization maps, and generating an explanation map of the output determination of the CNN based on the plurality of visualization maps.
    Type: Application
    Filed: August 18, 2021
    Publication date: February 24, 2022
    Applicants: LG ELECTRONICS INC., The Governing Council of the University of Toronto
    Inventors: Jongseong Jang, Hyunwoo Kim, YeonJeong Jeong, SangMin Lee, Sam Sattarzadeh, Mahesh Sudhakar, Shervin Mehryar, Anthony Lem, Konstantinos Plataniotis
  • Synthetic antibodies against VEGF and their uses
    Patent number: 11254738
    Abstract: The invention provides novel synthetic antibodies directed against VEGF and uses thereof.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: February 22, 2022
    Assignees: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO BANTING INSTITUTE, SAKSIN LIFESCIENCES PVT. LTD.
    Inventors: Frederic Fellouse, Jason Moffat, Sachdev Sidhu, Cn Ramchand, Ravikant Harit, Reena Arora, Aju Antony, Santhi Vinodh
  • Amplification of nanoparticle based assay
    Patent number: 11248255
    Abstract: An automated multiplex detector system includes: (a) a nucleic acid amplification compartment for amplifying nucleic acid of one or more targets in a sample, and (b) an analysis compartment in fluid communication with the amplification compartment, the analysis compartment housing a nanoparticle-based multiplex detector capable of using the amplified nucleic acid of the amplification compartment and producing a signal that correlates with the presence of the one or more targets in the sample.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: February 15, 2022
    Assignee: The Governing Council of the University of Toronto
    Inventors: Warren C. W. Chan, Jisung Kim, Kyrylo Zagorovsky
  • Method for dissociating cell aggregates
    Patent number: 11242503
    Abstract: A method for dissociating cell aggregates in an agitated reactor. The method comprises providing a cell culture comprising cell aggregates in the agitated reactor, contacting the cell aggregates with a dissociation reagent, generating a dissociation force in the agitated reactor and exposing the contacted cell aggregates to the generated dissociation force under conditions sufficient to dissociate the contacted cell aggregates. The method may be used in a process for passaging cells and/or generating dissociated differentiated cells from stem and/or progenitor cells.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: February 8, 2022
    Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Nicholas Timmins, Lesley Chan
  • Homogeneously dispersed multimetal oxy-hydroxide catalysts
    Patent number: 11230774
    Abstract: The present disclosure provides substantially homogeneously dispersed multimetal oxy-hydroxide catalyst comprising at least two metals, at least one metal being a transition metal, and at least a second metal which is structurally dissimilar to at least one metal, such that the multimetal oxy-hydroxide is characterized by being substantially homogeneously dispersed and generally not crystalline. A key feature of the present materials is that the presence of the structurally dissimilar metal results in sufficient strain produced in the final multimetal oxy-hydroxide material to prevent crystallization from occurring. The resulting materials are specifically not annealed at temperatures that would induce crystallization in order to avoid the expected phase segregation that would occur during crystallization.
    Type: Grant
    Filed: January 30, 2017
    Date of Patent: January 25, 2022
    Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Bo Zhang, Xueli Zheng, Oleksandr Voznyy, Sjoerd Hoogland, Jixian Xu, Min Liu, Cao-Thang Dinh, Edward Sargent
  • CD133-binding agents and uses thereof
    Patent number: 11220551
    Abstract: This disclosure is directed to novel CD133-binding agents. The disclosure is also directed to uses of novel CD133-binding agents for detecting CD133-expressing cells and/or quantitating levels of cellular CD133 expression, for targeting CD133-expressing cells, for decreasing levels of CD133 in CD133-expressing cells and for treating or preventing cancer.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: January 11, 2022
    Assignees: The Governing Council of the University of Toronto, McMaster University
    Inventors: Jason Moffat, Jarrett Adams, Guohua Pan, Sachdev Sidhu, Rashida Williams, Xiaoyu Zhang, Sheila K. Singh, Parvez Vora, Chitra Venugopal
  • On-board bidirectional AC fast charger for electric vehicles
    Patent number: 11217996
    Abstract: An electric vehicle fast charger and methods thereof are described, adapted for re-use of magnetic components of an electric vehicle having traction converters when the electric vehicle is stationary and connected to a power grid. A switching stage provided by one or more sets of switches is controlled complementarily with the switches of the traction converters to (i) provide inversion of a grid voltage and (ii) shape current of the grid current between the electric vehicle and the power grid to track a waveshape of the grid voltage. A single switching stage and a dual switching stage circuit are contemplated, along with switch controller circuits, and instruction sets for switch control. Variants provide for energy transfer to accommodate for energy imbalances between storage devices.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: January 4, 2022
    Assignees: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO, ELEAPPOWER LTD.
    Inventors: Peter Lehn, Theodore Soong, Philippe Gray, Sepehr Semsar
  • DEEP-LEARNING FOR DISTRIBUTED CHANNEL FEEDBACK AND PRECODING
    Publication number: 20210410135
    Abstract: Some embodiments of the present disclosure provide a deep-learning-based framework for designing components of a downlink precoding system. The components of such a system include downlink training pilots and channel estimation based on receipt of the downlink training pilots. Another component involves channel measurement and feedback strategy at the user equipment. The components include a precoding scheme designed at the base station based on the feedback from the user equipment.
    Type: Application
    Filed: June 26, 2020
    Publication date: December 30, 2021
    Applicants: HUAWEI TECHNOLOGIES CANADA CO., LTD., THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: WEI YU, FOAD SOHRABI, KAREEM ATTIAH ALBORAIE, MOHAMMADHADI BALIGH
  • Computational imaging of the electric grid
    Patent number: 11212459
    Abstract: Systems and methods for imaging scenes illuminated by light sources that are powered by alternating current. Data concerning these light sources are extracted from the imagery. Systems comprising a rolling shutter imaging sensor and configured to de-flicker images with spatial flicker are also provided.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: December 28, 2021
    Assignees: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED, THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Mark Sheinin, Yoav Schechner, Kiriakos Neoklis Kutulakos, Yoash Levron
  • Bio-inspired polyflavin electrodes for energy storage devices
    Patent number: 11211608
    Abstract: The present disclosure provides the use of a biomolecule, flavin, appended to a polymerizable unit that can then be polymerized to form an electroactive active polymer. The polymer and the flavin unit are comprised of an organic material containing C, H, N, and O atoms. The electroactive functionality is related to the double bonds that are present in the flavin unit that are appended to a non-electroactive backbone. This appended unit is rendered insoluble in the electrolyte of the discussed secondary battery unit. Several different molecular structures are disclosed exhibiting efficacy as energy storage medium in energy storage devices. Compounds have also been synthesized from which these different energy storage molecular structures are produced.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: December 28, 2021
    Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Dwight Seferos, Tyler Brian Schon, Colin Richard Bridges