Patents Assigned to William H. Rorer, Inc.
  • Amidinoureas
    Patent number: 4440949
    Abstract: A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-secretory, anti-spasmodic, anti-ulcerogenic and anti-diarrheal agents.
    Type: Grant
    Filed: December 30, 1980
    Date of Patent: April 3, 1984
    Assignee: William H. Rorer, Inc.
    Inventors: George H. Douglas, William L. Studt, Stuart A. Dodson
  • Heterocyclic amidinoureas
    Patent number: 4436911
    Abstract: This invention relates to a novel class of heterocyclic amidinourea and heterocylic amidinothiourea compounds wherein the heterocyclic substitution is at the 1-N urea nitrogen atom. These compounds exhibit pharmaceutical activity and may be incorporated into pharmaceutical preparations for producing anti-ulcerogenic, antisecretory, antispasmodic, antimotility, cardiovascular, antidiarrheal or antiparasitic action.
    Type: Grant
    Filed: May 12, 1981
    Date of Patent: March 13, 1984
    Assignee: William H. Rorer, Inc.
    Inventors: William L. Studt, Harry K. Zimmerman, George H. Douglas
  • Pyridone compounds
    Patent number: 4432979
    Abstract: Cardiotonic 5-heteroaryl-substituted-2-pyridone compounds, pharmaceutical compositions, and a method for the treatment of congestive heart failure.
    Type: Grant
    Filed: August 23, 1982
    Date of Patent: February 21, 1984
    Assignee: William H. Rorer, Inc.
    Inventor: Henry F. Campbell
  • Amidinothioureas
    Patent number: 4418209
    Abstract: This invention describes a new class of 1-amidino-3-phenylthiourea and N'-phenylamidinothiourea compounds wherein the phenyl group is ortho substituted, and processes for their preparation. The phenylamidinothiourea compounds may be incorporated into pharmaceutical preparations which are useful for producing anti-ulcerogenic, antisecretory, antispasmodic, antihypertensive, anti-arrhythmic, anesthetic, antidiarrheal and antiparasitic action.
    Type: Grant
    Filed: December 21, 1981
    Date of Patent: November 29, 1983
    Assignee: William H. Rorer, Inc.
    Inventors: George H. Douglas, Julius Diamond, William L. Studt, Stuart A. Dodson
  • 6-Aryl-4-hydrazinyl-s-triazin-2-ones
    Patent number: 4406897
    Type: Grant
    Filed: July 6, 1981
    Date of Patent: September 27, 1983
    Assignee: William H. Rorer, Inc.
    Inventors: Henry F. Campbell, Thomas H. Scholz, George H. Douglas
  • 1-Methylene-1-phenylguanidine compounds
    Patent number: 4393077
    Abstract: Compounds having the formula: ##STR1## wherein X.sub.1, X.sub.2, R, R.sub.1, R.sub.2 and R.sub.3 are as set forth hereinafter, their preparation and uses as ganglionic blocking agents are disclosed.
    Type: Grant
    Filed: July 2, 1981
    Date of Patent: July 12, 1983
    Assignee: William H. Rorer, Inc.
    Inventors: George H. Douglas, Henry F. Campbell
  • Method and composition for treating acne
    Patent number: 4388301
    Abstract: A method of treating skin conditions utilizing a deodorized composition containing soluble polysulfide compounds and the composition therefor.
    Type: Grant
    Filed: April 30, 1982
    Date of Patent: June 14, 1983
    Assignee: William H. Rorer, Inc.
    Inventor: Robert W. Klein
  • Heterocyclic alkylene triazinones
    Patent number: 4387225
    Abstract: Heterocyclic alkyl s-triazine compounds are prepared from the corresponding amidinourea and amidinothiourea compounds by reacting with an activated form of an acid amide to give respectively substituted s-triazinones and thiones of the formula ##STR1## which have pharmacological properties that render them suitable for use for a variety of medicinal purposes, including use as antidiarrheal agents, and which are also useful derivatives in analyzing for the corresponding amidinourea or amidinothiourea precursors.
    Type: Grant
    Filed: May 12, 1981
    Date of Patent: June 7, 1983
    Assignee: William H. Rorer, Inc.
    Inventors: George H. Douglas, William L. Studt, Chong M. Won, Stuart A. Dodson, Jerome J. Zalipsky
  • Ethynylbenzene compounds and derivatives thereof
    Patent number: 4365093
    Abstract: Novel ethynylbenzene compounds and their derivatives which are useful for the treatment for the relief of inflammation, pain and fever.
    Type: Grant
    Filed: November 23, 1976
    Date of Patent: December 21, 1982
    Assignee: William H. Rorer, Inc.
    Inventor: Julius Diamond
  • Amidinoureas
    Patent number: 4353842
    Abstract: A novel method of treating gastrointestinal, spasmolytic and ulcerogenic disorders by the administration of amidinoureas is disclosed.
    Type: Grant
    Filed: February 5, 1980
    Date of Patent: October 12, 1982
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, George H. Douglas
  • Amidinourea derivative veterinary compositions for suppression of parasitemia
    Patent number: 4340609
    Abstract: Therapeutic compositions containing an amidinourea are used in the treatment of animals infested with blood residing parasites, particularly parasitic protozoal infestations of the blood and blood-forming organs.
    Type: Grant
    Filed: January 2, 1980
    Date of Patent: July 20, 1982
    Assignee: William H. Rorer, Inc.
    Inventor: Billy J. Chou
  • Triazinones
    Patent number: 4338441
    Abstract: Novel s-triazine compounds are prepared as derivatives of the corresponding amidinourea and amidinothiourea compounds by reacting with an activated form of an acid amide to give substituted s-triazinones and thiones respectively, of the formula ##STR1## The s-triazinones and thiones are useful derivatives in analyzing for the corresponding amidinourea or amidinothiourea precursors and also have useful pharmacological properties which make them suitable for a variety of medicinal purposes including use as antidiarrheal agents.
    Type: Grant
    Filed: January 15, 1981
    Date of Patent: July 6, 1982
    Assignee: William H. Rorer, Inc.
    Inventors: George H. Douglas, William L. Studt, Chong M. Won, Stuart A. Dodson, Jerome J. Zalipsky
  • Amidinoureas
    Patent number: 4326075
    Abstract: A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-diarrheal agents.
    Type: Grant
    Filed: February 5, 1980
    Date of Patent: April 20, 1982
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, George H. Douglas
  • Amidinoureas
    Patent number: 4326074
    Abstract: A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-diarrheal agents.
    Type: Grant
    Filed: December 18, 1979
    Date of Patent: April 20, 1982
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, George H. Douglas
  • Amidinoureas
    Patent number: 4304786
    Abstract: A novel method of treating gastrointestinal, spasmolytic and ulcerogenic disorders by the administration of amidinoureas is disclosed.
    Type: Grant
    Filed: July 23, 1979
    Date of Patent: December 8, 1981
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, George H. Douglas
  • Method for blocking high frequency nerve stimulation
    Patent number: 4298608
    Abstract: 1,4-Disubstituted-1,2-dihydro-1,3,5-triazin-2-ones are used to block conduction of high frequency nerve impulses by selectively acting to substantially completely block high frequency impulses without significantly blocking conduction of a single impulse. The effect is reversible when the drug is withdrawn.
    Type: Grant
    Filed: April 11, 1980
    Date of Patent: November 3, 1981
    Assignee: William H. Rorer, Inc.
    Inventors: George A. Condouris, John Yelnosky, Richard L. Riley, Chong M. Won, George H. Douglas, William L. Studt
  • Ethynylbenzene compounds and derivatives thereof
    Patent number: 4296264
    Abstract: Novel halo substituted ethynylbenzene compounds that are useful in the treatment of inflammation.
    Type: Grant
    Filed: October 19, 1977
    Date of Patent: October 20, 1981
    Assignee: William H. Rorer, Inc.
    Inventor: Julius Diamond
  • Ethynylbenzene compounds and derivatives thereof
    Patent number: 4288457
    Abstract: Novel ethynylbenzene compounds and derivatives are described. Their use in the treatment of inflammation is also disclosed.
    Type: Grant
    Filed: May 14, 1975
    Date of Patent: September 8, 1981
    Assignee: William H. Rorer, Inc.
    Inventor: Julius Diamond
  • Method of treating scours
    Patent number: 4285972
    Abstract: Scours in animals, particularly new-born calves, lambs, piglets and foals are treated with a compound containing an effective amount of an antidiarrheal amidinourea.
    Type: Grant
    Filed: August 13, 1979
    Date of Patent: August 25, 1981
    Assignee: William H. Rorer, Inc.
    Inventors: Billy J. Chou, John Yelnosky, Richard L. Riley
  • Amidinoureas
    Patent number: 4283555
    Abstract: This invention describes novel chemical compounds which are 1-amidino-3-phenylureas. The method of preparing these compounds and their pharmaceutical uses is also disclosed.
    Type: Grant
    Filed: March 2, 1979
    Date of Patent: August 11, 1981
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, Jerome J. Zalipsky