Abstract: A microbicidal disinfecting composition and a method of preparing the same include the use of an acidifying agent that comprises at least one of an alkali metal bisulfate, ammonium bisulfate, or a combination thereof. The composition has broad-spectrum microbicidal properties and does not demonstrate cloudiness or precipitation when prepared, diluted, or otherwise exposed to hard water.
Abstract: Porous resin particles are disclosed that comprise a polymer of a monomer mixture. The monomer mixture includes: a mono(meth)acrylate-based monomer in an amount of 3 wt % to 40 wt % containing: an ethylenic unsaturated group only in a (meth)acrylic acid residue; and a hydroxyl group and at least either an ether group or an ester group in an alcohol residue; another monofunctional vinyl-based monomer in an amount of 10 wt % to 69 wt % containing a single ethylenic unsaturated group; and a polyfunctional vinyl-based monomer in an amount of 30 wt % to 70 wt % containing two or more ethylenic unsaturated groups.
Abstract: The present invention relates to a method of treating hepatitis in a patient, which includes administering a pharmaceutical composition that includes carbon monoxide to the patient.
Type:
Grant
Filed:
December 2, 2013
Date of Patent:
December 20, 2016
Assignees:
University of Pittsburgh—Of the Commonwealth System of Higher Education, Yale University
Inventors:
Leo E. Otterbein, Augustine M. K. Choi, Brian Scott Zuckerbraun
Abstract: The invention relates to particles including, relative in each case to the particle weight, 30 to 90 wt. % of polyalphaolefin wax(es) and 10 to 70 wt. % of one or more cosmetic active agents, selected from fragrances, cooling active agents and mixtures of fragrances and cooling active agents, as well as to cosmetic compositions containing water and 0.01 to 10 wt. %, relative to the weight of the cosmetic composition, of one or more of the aforementioned particles.
Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral pharmaceutical compositions comprising fumarate esters are described.
Type:
Grant
Filed:
March 18, 2016
Date of Patent:
December 13, 2016
Assignee:
Banner Life Sciences LLC
Inventors:
Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
Abstract: Disclosed are water-based cosmetic compositions comprising a synthetic non-associative thickening polymer, a synthetic associative thickening polymer, an emulsifier, a film forming polymer, and a liquid fatty substance. The ratio of the synthetic non-associative thickening polymer to the synthetic associative thickening polymer is greater than 1:1, or alternatively, said ratio is less than or equal to 1:1.
Type:
Grant
Filed:
March 21, 2014
Date of Patent:
December 13, 2016
Assignee:
L'OREAL
Inventors:
Christine Marie Crane, Angeles Fonolla-Moreno
Abstract: The present disclosure is directed to an implantable repository including a housing comprising at least one bioactive agent and at least one attachment member coupled to the housing, the at least one attachment member configured to couple the implantable repository to at least one of a medical device and a tissue surface.
Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral pharmaceutical compositions comprising fumarate esters are described.
Type:
Grant
Filed:
March 18, 2016
Date of Patent:
December 6, 2016
Assignee:
Banner Life Sciences LLC
Inventors:
Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
Abstract: A polymeric composition comprising a copolymer of ethylene with at least another monomer comprising at least a heteroatom, a tackifier, less than 10% of a compatible plasticizer or blend of plasticizers and a volatile material. The compositions are able to deliver effectively the volatile material incorporated for a long time and also have good adhesion properties on most substrates.
Abstract: Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced stability for the bioactive material. Compositions containing the bioactive materials may be produced by a method that includes (a) combining the bioactive material with other ingredients in an aqueous solvent to form a viscous slurry; (b) snap-freezing the slurry in liquid nitrogen to form solid frozen particles, beads, droplets or strings; (c) primary drying by water removal under vacuum of the product of step (b) while maintaining it at a temperature above its freezing temperature; and (d) secondary drying of the product of step (c) at maximum vacuum and a temperature of 20° C. or higher for a time sufficient to reduce the water activity to below 0.3 Aw.
Type:
Grant
Filed:
March 25, 2013
Date of Patent:
November 29, 2016
Assignee:
ADVANCED BIONUTRITION CORPORATION
Inventors:
Moti Harel, Qiong Tang, Trisha Rice, Kimberly Jennings, Brian Carpenter, Roger Drewes, Elizabeth Raditsis, January Scarbrough
Abstract: An edible animal medicine container for delivering medicine or other ingestible material, contained therein, to an animal, includes first and second edible housing shells. The first shell includes a first peripheral ledge, surrounding a first central hollow, and a first interlocking feature extending therefrom. The second shell includes a second peripheral ledge, surrounding a second central hollow, and a second interlocking feature extending into, and at least partially defined by, the second peripheral ledge. The second shell is positionable relative to, and connectable to, the first shell to define an interior in which the ingestible material may be disposed. In such connected state the first interlocking feature is seated and frictionally held within the second interlocking feature of the second edible housing shell so as to retain the first and second shells together and thereby retain the ingestible material within the interior until ingested by an animal.
Type:
Grant
Filed:
September 30, 2014
Date of Patent:
November 22, 2016
Assignee:
Make Ideas, LLC
Inventors:
Keith Alan Mullin, William Bradley Allen
Abstract: Formulations, kits, and methods for rebuilding the disulfide bonds in keratin found in hair, skin, or nails. Hair that is damaged due to a hair coloring treatment and/or other reducing treatment, such as during a permanent wave, can be treated with the formulations containing one or more active agents. The formulations may be applied subsequent to a hair coloring treatment or simultaneously with a hair coloring treatment. Use of the active agent formulations during a permanent wave treatment prevents the reversion of the hair to its previous state, for at least one week, preferably at least three months, more preferably at least one year, most preferably greater than one year, after one or more than one application of the formulation. Application of the active agent formulation to skin or nails can help repair damaged disulfide bonds due to natural wear and tear or natural aging.
Abstract: Methods of using oxidative reduction potential (ORP) water solution that is stable for at least twenty-four hours in dental applications are provided. The ORP water solution can be administered to patients for the routine disinfection of the oral cavity as part of an on-going program of oral hygiene. The ORP water solution can further be used to irrigate and/or disinfect oral tissues and surfaces during dental procedures, oral surgery, or maxillo-facial surgery. Also, the ORP water solution can be administered to treat patients with damage to the oral tissues caused by disease or surgery.
Abstract: Prostamide-containing intraocular implants that biodegrade in the eye and that are effective for reducing intraocular pressure in an eye for a sustained period. The implants generally contain a prostamide, such as bimatoprost, and at least three distinct biodegradable polymers selected from polylactide and poly(lactide-co-glycolide) polymers and are optimized for placement in and compatibility with the anterior chamber of the eye, particularly the anterior chamber angle. Methods for making and using the implants to reduce ocular hypertension and intraocular pressure in a patient are described.
Type:
Grant
Filed:
October 31, 2014
Date of Patent:
November 15, 2016
Assignee:
Allergan, Inc.
Inventors:
Alazar N. Ghebremeskel, Michael R. Robinson
Abstract: The present invention provides a composition comprising an active ingredient with a maximum solubility in water at 20° C. of 10 g/l, and a hyperbranched polyester which is joined to a polar polymer which comprises a polycondensate or a polymer comprising ethylenically unsaturated monomers. The invention further relates to the hyperbranched polyester mentioned and to a process for preparation thereof. It further relates to the use of the hyperbranched polyester for solubilizing the active ingredient in aqueous compositions.
Type:
Grant
Filed:
December 15, 2010
Date of Patent:
November 15, 2016
Assignee:
BASF SE
Inventors:
Holger Türk, Monika Haberecht, Hiroe Yamada, Bernd Bruchmann, Daniel Schönfelder, Michael Ishaque, Joachim Clauss
Abstract: An oil in water microemulsion or sub-micron emulsion composition for dermal delivery of desonide is provided, along with a method of medical or cosmetic treatment of a dermal condition using the composition. The composition includes desonide; an oil phase dispersed throughout a water phase, the oil phase including at least one member selected from the group consisting of an animal oil, a mineral oil, a vegetable oil, a silane member, a siloxane, an ester, a fatty acid, a fat, a halogen compound, and an alkoxylated alcohol; and at least one lipophilic surfactant, the water phase including at least one hydrophilic surfactant and water; and a non-surfactant amphiphilic compound that is miscible in the water phase and added to the composition after formation of the microemulsion or sub-micron emulsion; wherein the desonide is in the water phase or both the water phase and the oil phase.
Type:
Grant
Filed:
February 24, 2015
Date of Patent:
November 15, 2016
Assignee:
STIEFEL WEST COAST LLC
Inventors:
Maria Graziella Larm, Ronald Harding, Michael Johnston, Albert Zorko Abram, Prema Viyayakumar, Phoebe Sun
Abstract: The invention relates to an alcohol-free cosmetic or pharmaceutical foam composition comprising water, a hydrophobic solvent, a surface-active agent, a gelling agent, an active component selected from the group of urea, hydroxy acid and a therapeutic enhancer and a propellant. The foam further comprises active agents and excipients with therapeutic properties having enhanced skin penetration.
Type:
Grant
Filed:
April 22, 2014
Date of Patent:
November 15, 2016
Assignee:
Foamix Pharmaceuticals Ltd.
Inventors:
Dov Tamarkin, Doron Friedman, Meir Eini
Abstract: The present invention relates to an insecticide-containing fabric containing at least one embedded insecticidally active ingredient in the polymeric matrix and having excellent wash resistance, and also to the products produced from this fabric and to their use for protecting humans, animals and plants against arthropods, particularly for controlling insects.
Type:
Grant
Filed:
October 14, 2014
Date of Patent:
November 8, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Rainer Sonneck, Thomas Böcker, Karin Horn, Guenther Nentwig, Maren Heinemann, Thomas König
Abstract: A method of effecting at least one biological process in a plant is disclosed. The method comprises contacting a part of a seed, a plant, or the locus thereof with a mixture comprising an agriculturally acceptable mixture of (i) complex polymeric polyhydroxy acids and (ii) a phytotoxic amount of one or more alkali (earth) salts and/or a synergistic amount of at least one source of an agriculturally acceptable transition metal ions.
Type:
Grant
Filed:
January 11, 2013
Date of Patent:
November 8, 2016
Assignee:
FBSCIENCES HOLDINGS, INC.
Inventors:
Terry J. Hanson, Kenneth Scott Day, Johan Peter Stromberg