Patents Examined by Abigail Fisher
  • Multiphasic bone graft substitute material
    Patent number: 9446170
    Abstract: The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, comprising i) a calcium sulfate hemihydrate powder, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 50 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; iii) a non-porous ?-tricalcium phosphate powder; and iv) a porous ?-tricalcium phosphate powder. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: September 20, 2016
    Assignee: Agnovos Healthcare, LLC
    Inventors: Jon Moseley, Jamie MacDougall, Katie Harrigan
  • Methods of ameliorating oxidative stress by increasing the efficiency of GPX and SOD activity
    Patent number: 9446072
    Abstract: Methods of ameliorating cellular oxidative stress are disclosed. The methods include contacting at least one cell with a composition comprising a mixture of reduced species (RS) and reactive oxygen species (ROS). The mixture of reduced species (RS) and reactive oxygen species (ROS) mirrors a target mixture where the target mixture is the reduced species (RS) and reactive oxygen species (ROS) found in a known biological system.
    Type: Grant
    Filed: April 5, 2013
    Date of Patent: September 20, 2016
    Assignee: Reoxcyn Discoveries Group, Inc.
    Inventors: Gary Samuelson, Verdis Norton
  • Fungicide active substance combinations
    Patent number: 9445601
    Abstract: The novel active compound combinations comprising 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione of the formula and the active compound of groups (1) to (24) listed in the description have very good fungicidal properties.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: September 20, 2016
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Stefan Dutzmann, Klaus Stenzel, Manfred Jautelat
  • Coating for a surface
    Patent number: 9447304
    Abstract: Coatings for a surface, especially a priming coating, of the present invention have been found to be durable, resistant to oxidative degradation, erosion and depolymerization, stable to sterilization and low particulating, and are easily applied to the required surface of a substrate in a surface-independent manner. Such coatings, when used as priming coatings to be coated with a subsequent coating, in at least some embodiments, form exterior coatings which are also highly durable and are stable to sterilization and aging.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: September 20, 2016
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Paul D. Drumheller, Charles D. Claude
  • Dry powder inhaler and system for drug delivery
    Patent number: 9446133
    Abstract: A breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system are provided. The dry powder inhaler can be provided with or without a unit dose cartridge for using with the inhaler. The inhaler and/or cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, peptides and proteins such as insulin and glucagon-like peptide 1 for the treatment of diabetes and/or obesity. The dry powder inhaler is compact; can be provided in various shapes and sizes, colors, and comprises a housing, a mouthpiece, a cartridge placement area, and a mechanism for opening and closing the medicament cartridge. The device is easy to manufacture, provides a pre-metered single unit dose, it is relatively easy to use, and can be reusable or disposable.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: September 20, 2016
    Assignee: MannKind Corporation
    Inventors: Chad C. Smutney, P. Spencer Kinsey, Carl R. Sahi, Benoit Adamo, John M. Polidoro, Scott McLean, Dennis Overfield, Kelly S. Kraft, Karla Somerville
  • Active agent microparticles
    Patent number: 9439870
    Abstract: The present invention concerns polymeric-enveloped microparticles including at least one HASE type acrylic copolymer, at least one solid-liquid phase change material with a phase transition temperature ranging from 20 to 90° C., and at least one active agent. In particular, the microparticles include at least one HASE type acrylic copolymer including at least one anionic monomer with a polymerizable vinyl group and a carboxyl group, at least one non-ionic hydrophobic monomer with a polymerizable vinyl group, and at least one alkoxylated associative macromonomer with a polymerizable vinyl group and a hydrophobic hydrocarbon chain.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: September 13, 2016
    Assignee: COATEX
    Inventors: Clementine Champagne, Jean-Marc Suau, Olivier Guerret
  • Coating film, and granules and tablets each utilizing same
    Patent number: 9439865
    Abstract: A coating film comprising ethyl cellulose as a component A and an (ethyl acrylate)-(methyl methacrylate) copolymer or a plasticized vinyl acetate polymer as a component B, and having a tensile elongation of 150% or more and a tensile strength of 9 N or more.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: September 13, 2016
    Assignee: ASAHI KASEI CHEMICALS CORPORATION
    Inventors: Naoya Yoshida, Kazuhiro Obae
  • Antiwrinkle composition and age reversal complex
    Patent number: 9440098
    Abstract: An alkaline anti-wrinkling composition comprising carnosine, derivative thereof, or mixture of carnosine, and derivative thereof.
    Type: Grant
    Filed: March 16, 2006
    Date of Patent: September 13, 2016
    Inventor: Naina Sachdev
  • Stable bubbles via particle absorption by electrostatic interaction
    Patent number: 9433578
    Abstract: Disclosed are methods of preparing stable gas-in-solution emulsions by particle adsorption via electrostatic interaction, and stable emulsions prepared by particle adsorption via electrostatic interaction. Compositions and products comprising the emulsions are also disclosed. Emulsions may be stable over an extended period of time at room temperature.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: September 6, 2016
    Assignee: L'OREAL
    Inventors: Vance Bergeron, Jean-Thierry Simonnet, Florence Levy, Aurelie Lafuma, Stephane Santucci
  • Coatings with crystallized active agent(s) and methods
    Patent number: 9427501
    Abstract: Coatings with crystallized active agent(s) and related methods are disclosed. One method includes selecting a solvent and a polymer, selecting a concentration of an active agent of at least a certain amount of saturation, forming a coating composition having the selected concentration of the active agent, and applying the coating composition to the medical device. Also disclosed is an elution control coating which includes an active agent that is at least about 80% crystallized within one week of being disposed on a medical device. One method enhances the formation of active agent crystals within a coating layer by adjusting the concentration of the active agent in the coating solution to reach some percentage of the active agent saturation point. Another method includes increasing the rate of active agent nucleation within the coating.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: August 30, 2016
    Assignee: Surmodics, Inc.
    Inventors: Ralph A. Chappa, Kimberly K. M. Lindsoe
  • Composition and method for aiding sleep
    Patent number: 9427409
    Abstract: Described is a controlled-release formulation for treating disturbed sleep or insomnia in a subject. The formulation is formulated to release a compound or combination of compounds in sequence at multiple stages.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: August 30, 2016
    Assignee: Sequential Medicine Limited
    Inventor: Lan Bo Chen
  • Nutritional formulation
    Patent number: 9420819
    Abstract: The present invention relates to nutritional supplements that provide an adult with essential vitamins and minerals that may be lacking in the adult's diet and prevent chronic diseases, such as osteoporosis. A number of combinations of nutrients in set ratios are provided to increase the body's ability to absorb and use the nutrients. These combinations are important in helping the body reach the proper balance required for maximized function. Because adults over the age of 50 years have different nutritional needs, nutritional supplements specifically designed for them are also provided.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: August 23, 2016
    Assignee: Wyeth LLC
    Inventors: Richard Cotter, Randy Stodard
  • Pesticidal composition in the form of aqueous emulsion
    Patent number: 9420782
    Abstract: A pesticidal composition in the form of an aqueous emulsion contains: (a) an agriculturally active ingredient in which a retention rate is 50% or more after irradiation with xenon light (290 nm cutoff) at an intensity of 0.68 W/m2 at 340 nm for 8 hours, and a retention rate is 40% or more and 60% or less after irradiation for 56 hours; (b) a hydrophobic organic solvent; (c) a water-soluble polymer dispersing agent; and (d) water; wherein liquid droplets in which the agriculturally active ingredient is suspended or dissolved in the hydrophobic organic solvent are emulsified in an aqueous continuous phase. A weight ratio of the agriculturally active ingredient to the hydrophobic organic solvent is from 5:95 to 70:30. With this pesticidal composition, it is possible to inhibit photodegradation of the agriculturally active ingredient.
    Type: Grant
    Filed: June 20, 2013
    Date of Patent: August 23, 2016
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Kazuyuki Yanagisawa, Motofumi Mizutani
  • Allergen dosage form
    Patent number: 9415015
    Abstract: The invention provides allergen containing pharmaceutical products and in particular fast-dispersing solid allergen dosage forms. In particular, fast-dispersing, non-compressed solid dosage forms suitable for oromucosal administration comprising a matrix and at least one allergen are provided. Suitable matrices are gelatine, starch and mannitol. Methods for the dosage forms are also provided.
    Type: Grant
    Filed: April 4, 2008
    Date of Patent: August 16, 2016
    Assignees: ALK-Abello A/S, R.P. Scherer Technologies, LLC
    Inventors: Henrik Hugo Jacobi, Annette Roemmelmayer Lundegaard, Christian Gauguin Houghton, Stig Aasmul-Olsen, Lise Lund Maerkedahl, Jan Sondergaard Andersen, Kerry Mallindine, Owen James Murray, Susan Gerrard Banbury, Desmond Yik Teng Wong, Lisa Marie Garrett, Michael Hall
  • Allergen dosage form
    Patent number: 9408805
    Abstract: The invention provides allergen containing pharmaceutical products and in particular fast-dispersing solid allergen dosage forms. In particular, fast-dispersing, non-compressed solid dosage forms suitable for oromucosal administration comprising a matrix and at least one allergen are provided. Suitable matrices are gelatine, starch and mannitol. Methods for the dosage forms are also provided.
    Type: Grant
    Filed: May 27, 2014
    Date of Patent: August 9, 2016
    Assignees: ALK-Abello A/S, R.P. Scherer Technologies, LLC
    Inventors: Henrik Hugo Jacobi, Annette Roemmelmayer Lundegaard, Christian Gauguin Houghton, Stig Aasmul-Olsen, Lise Lund Maerkedahl, Jan Sondergaard Andersen, Kerry Mallindine, Owen James Murray, Susan Gerrard Banbury, Desmond Yik Teng Wong, Lisa Marie Garrett, Michael Hall
  • Zeolites for delivery of nitric oxide
    Patent number: 9402862
    Abstract: There is described zeolites containing releasably adsorbed nitric oxide, methods of preparing the zeolites, methods of releasing the nitric oxide into a solution or into air and uses of the zeolites in therapy.
    Type: Grant
    Filed: September 2, 2010
    Date of Patent: August 2, 2016
    Assignee: University Court of the University of St Andrews
    Inventors: Russell Edward Morris, Paul Stewart Wheatley, Anthony Robert Butler
  • Zinc oxide powder, dispersion, paint, and cosmetic material
    Patent number: 9403691
    Abstract: Zinc oxide powder of the present invention has a specific surface area which is in a range of 1.5 m2/g to 65 m2/g, a conductivity which is 150 ?S/cm or less and a bulk specific volume which is in a range of 0.5 mL/g to 10 mL/g.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: August 2, 2016
    Assignee: Sumitomo Osaka Cement Co., Ltd.
    Inventors: Tadashi Neya, Tetsuro Itagaki, Syunsuke Suma
  • Mosquito attractant compositions and methods
    Patent number: 9392788
    Abstract: Provided are compositions for attracting and/or stimulating oviposition. The compositions comprise a suitable carrier and a bacterium capable of producing nonanoic acid, tetradecanoic acid, or methyl tetradecanoate; Bacillus thuringiensis; Lactococcus lactis; Klebsiella oxytoca; Shigella dysenteriae; Brevundimonas vesicularis; a supernatant of a culture of any of the these bacteria; nonanoic acid; tetradecanoic acid; or methyl tetradecanoate, or any combination thereof, at a concentration effective to attract the mosquito to a target. The compositions may be comprised within a kit or trap. Also provided are methods of attracting mosquitoes to a target.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: July 19, 2016
    Assignee: North Carolina State University
    Inventors: Loganathan Ponnusamy, Ning Xu, Coby Schal, Charles S. Apperson, Dawn Wesson
  • Compositions of dibromomalonamide and their use as biocides
    Patent number: 9392789
    Abstract: The application describes synergistic microbicidal compositions comprising: 2,2-dibromomalonamide and an oxidizing biocide selected from the group consisting of: monochloramine, bromochlorodimethylhydantoin, hypobromite ion or hypobromous acid, hydrogen peroxide, dichloroisocyanurate, trichloroisocyanurate and chlorine dioxide and a method for controlling microorganism growth in an aqueous or water-containing system.
    Type: Grant
    Filed: September 27, 2010
    Date of Patent: July 19, 2016
    Assignee: Dow Global Technologies LLC
    Inventors: Freddie L. Singleton, Bei Yin, Janardhanan S. Rajan
  • Application of mixotrophic chlorella for the improved yield and quality of solanaceae plants
    Patent number: 9386774
    Abstract: Methods of improving the yield and quality of plants in the Solanaceae family by administering an effective amount of a mixotrophic Chlorella based liquid composition in low concentration and low frequency applications are disclosed. The administration may comprise soil or foliar applications of the composition.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: July 12, 2016
    Assignee: Heliae Development, LLC
    Inventors: Sandip Shinde, Nicholas Donowitz, Michael Clint Rohlfsen